Project

ENCSR904DTN: DNase-seq of mouse liver in constant darkness

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Nr4a2

Z-value: 0.91

Motif logo

Transcription factors associated with Nr4a2

Gene Symbol	Gene ID	Gene Info
Nr4a2 Ensembl NCBI MGI UniProt	ENSMUSG00000026826.7	Nr4a2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Nr4a2	chr2_57117256_57117410	2295	0.311454	-0.73	1.0e-01	Click!
Nr4a2	chr2_57117046_57117226	2098	0.330338	-0.72	1.0e-01	Click!
Nr4a2	chr2_57127889_57128053	3968	0.231728	-0.53	2.8e-01	Click!
Nr4a2	chr2_57127237_57127406	3318	0.249139	0.50	3.1e-01	Click!
Nr4a2	chr2_57117679_57117833	2718	0.281748	0.43	3.9e-01	Click!

Activity of the Nr4a2 motif across conditions

Conditions sorted by the z-value of the Nr4a2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_110381296_110381622	1.12	Gm47195	predicted gene, 47195	56074	0.08
chr8_33950546_33950701	0.84	Rbpms	RNA binding protein gene with multiple splicing	20760	0.14
chr7_143519506_143519688	0.58	Nap1l4	nucleosome assembly protein 1-like 4	5063	0.12
chr8_112575848_112576026	0.50	Cntnap4	contactin associated protein-like 4	5882	0.26
chr6_11309873_11310042	0.48	AA545190	EST AA545190	330319	0.01
chr2_167351419_167351615	0.44	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	2334	0.3
chr13_91771771_91771922	0.44	Acot12	acyl-CoA thioesterase 12	7482	0.16
chr9_119405710_119405861	0.43	Gm47320	predicted gene, 47320	3231	0.15
chr12_86817069_86817235	0.42	Gm10095	predicted gene 10095	29315	0.15
chr9_69026149_69026327	0.41	Rora	RAR-related orphan receptor alpha	169303	0.04
chr15_26779223_26779382	0.41	Gm49266	predicted gene, 49266	33165	0.17
chr15_62137137_62137308	0.40	Pvt1	Pvt1 oncogene	38193	0.2
chr15_10330728_10330879	0.39	Gm21973	predicted gene 21973	5423	0.21
chr7_14438643_14438794	0.37	Sult2a8	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8	157	0.95
chr15_73153357_73153508	0.37	Ago2	argonaute RISC catalytic subunit 2	24415	0.17
chr3_11357506_11357684	0.37	Gm22547	predicted gene, 22547	203258	0.03
chr9_70138613_70138777	0.37	Fam81a	family with sequence similarity 81, member A	2883	0.24
chr5_77434274_77434480	0.36	Gm34728	predicted gene, 34728	343	0.85
chr1_140381210_140381379	0.35	Kcnt2	potassium channel, subfamily T, member 2	61642	0.14
chr2_49720215_49720366	0.35	Kif5c	kinesin family member 5C	2277	0.35
chr5_124076616_124076822	0.35	Abcb9	ATP-binding cassette, sub-family B (MDR/TAP), member 9	2412	0.16
chr15_84922812_84923048	0.34	Nup50	nucleoporin 50	481	0.69
chr17_77349186_77349376	0.34	Rpsa-ps8	ribosomal protein SA, pseudogene 8	13929	0.31
chr3_101617088_101617258	0.34	Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	12489	0.17
chr11_90224957_90225225	0.34	Mmd	monocyte to macrophage differentiation-associated	24365	0.15
chr1_67027218_67027385	0.34	Lancl1	LanC (bacterial lantibiotic synthetase component C)-like 1	5083	0.22
chr11_89991744_89991895	0.32	Pctp	phosphatidylcholine transfer protein	11075	0.24
chrX_155248406_155248561	0.32	Gm15159	predicted gene 15159	10985	0.13
chr1_140415820_140415994	0.32	Kcnt2	potassium channel, subfamily T, member 2	27029	0.25
chr12_71429918_71430089	0.31	1700083H02Rik	RIKEN cDNA 1700083H02 gene	45795	0.12
chr8_81634705_81634856	0.31	4930579O11Rik	RIKEN cDNA 4930579O11 gene	32292	0.22
chr11_40694837_40695013	0.31	Mat2b	methionine adenosyltransferase II, beta	62	0.97
chr18_52479162_52479313	0.31	Srfbp1	serum response factor binding protein 1	3858	0.22
chr13_23592766_23592917	0.31	H4c4	H4 clustered histone 4	11243	0.05
chrX_116629798_116629984	0.31	H2ab2	H2A.B variant histone 2	51287	0.17
chr2_72156547_72156849	0.30	Rapgef4os1	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 1	7902	0.2
chr12_112517104_112517266	0.30	Tmem179	transmembrane protein 179	438	0.8
chr13_69380527_69380680	0.29	Gm35514	predicted gene, 35514	14980	0.17
chr8_56443820_56444020	0.29	Gm7419	predicted gene 7419	9595	0.2
chr8_81366726_81366902	0.29	Inpp4b	inositol polyphosphate-4-phosphatase, type II	24252	0.21
chr11_43631833_43631984	0.29	Gm12149	predicted gene 12149	15579	0.14
chr2_122240654_122240966	0.28	Sord	sorbitol dehydrogenase	6061	0.11
chr11_31778535_31778713	0.28	D630024D03Rik	RIKEN cDNA D630024D03 gene	45849	0.13
chr5_72763116_72763280	0.27	Txk	TXK tyrosine kinase	10421	0.15
chr13_101929962_101930142	0.27	Gm17832	predicted gene, 17832	9632	0.26
chr2_169115164_169115359	0.27	Gm14258	predicted gene 14258	8808	0.23
chr18_66478212_66478424	0.27	Gm50156	predicted gene, 50156	13553	0.11
chr10_67185588_67186325	0.27	Jmjd1c	jumonji domain containing 1C	203	0.95
chr16_43343299_43343463	0.26	Zbtb20	zinc finger and BTB domain containing 20	19667	0.15
chr14_12201682_12201851	0.26	Ptprg	protein tyrosine phosphatase, receptor type, G	11823	0.2
chr3_149182211_149182384	0.26	Gm42647	predicted gene 42647	27974	0.19
chr11_16863303_16863761	0.26	Egfr	epidermal growth factor receptor	14618	0.19
chr1_136443150_136443310	0.26	Ddx59	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59	10828	0.14
chr4_150716478_150716631	0.26	Gm16079	predicted gene 16079	37762	0.15
chr2_48442189_48442365	0.25	Gm13481	predicted gene 13481	14968	0.23
chr13_109536856_109537007	0.25	Pde4d	phosphodiesterase 4D, cAMP specific	44474	0.21
chr10_110952952_110953127	0.25	Zdhhc17	zinc finger, DHHC domain containing 17	5342	0.19
chr10_19491378_19491765	0.25	Gm33104	predicted gene, 33104	3072	0.28
chr4_62723878_62724188	0.25	Gm11211	predicted gene 11211	3504	0.21
chr12_102711766_102711920	0.25	Itpk1	inositol 1,3,4-triphosphate 5/6 kinase	6913	0.1
chr13_31180346_31180513	0.25	Gm11372	predicted gene 11372	18657	0.21
chr4_137810112_137810287	0.24	Alpl	alkaline phosphatase, liver/bone/kidney	13815	0.19
chr11_58618424_58618625	0.24	2210407C18Rik	RIKEN cDNA 2210407C18 gene	2449	0.12
chrX_60348841_60349189	0.24	Mir505	microRNA 505	45477	0.14
chr19_29068353_29068504	0.24	Gm9895	predicted gene 9895	1081	0.38
chr10_17299753_17299932	0.23	Gm47761	predicted gene, 47761	21769	0.21
chr6_59072204_59072363	0.23	Gm22367	predicted gene, 22367	26970	0.15
chr10_116753155_116753338	0.23	4930579P08Rik	RIKEN cDNA 4930579P08 gene	23993	0.15
chr9_109964878_109965056	0.23	Map4	microtubule-associated protein 4	4050	0.14
chr15_41724355_41724527	0.23	Oxr1	oxidation resistance 1	13837	0.26
chr19_55251681_55251990	0.23	Acsl5	acyl-CoA synthetase long-chain family member 5	103	0.96
chr17_14168923_14169074	0.23	Gm34510	predicted gene, 34510	34730	0.12
chr8_18770899_18771050	0.23	Angpt2	angiopoietin 2	29412	0.16
chr10_67097331_67097523	0.23	Reep3	receptor accessory protein 3	482	0.67
chr1_51467935_51468124	0.23	Nabp1	nucleic acid binding protein 1	5367	0.2
chr17_35165511_35165752	0.23	Gm17705	predicted gene, 17705	512	0.34
chr3_12228257_12228414	0.23	Gm37996	predicted gene, 37996	156274	0.04
chr1_105921979_105922139	0.23	Gm26214	predicted gene, 26214	23495	0.14
chr5_111473915_111474088	0.22	Gm43119	predicted gene 43119	50412	0.12
chr1_156838356_156838519	0.22	Angptl1	angiopoietin-like 1	125	0.84
chr11_70845882_70846051	0.22	Rabep1	rabaptin, RAB GTPase binding effector protein 1	991	0.39
chr12_69517687_69517891	0.22	5830428M24Rik	RIKEN cDNA 5830428M24 gene	42239	0.1
chr9_98423674_98423967	0.22	Rbp1	retinol binding protein 1, cellular	859	0.64
chr1_23481107_23481287	0.22	Gm7784	predicted gene 7784	1658	0.46
chr8_115983569_115983746	0.22	Gm45733	predicted gene 45733	11586	0.31
chr17_31303465_31303616	0.21	Slc37a1	solute carrier family 37 (glycerol-3-phosphate transporter), member 1	2003	0.24
chr17_11092974_11093138	0.21	Gm28505	predicted gene 28505	3588	0.3
chr3_38360332_38360515	0.21	Gm42920	predicted gene 42920	8975	0.21
chr12_70459656_70459821	0.21	Tmx1	thioredoxin-related transmembrane protein 1	103	0.97
chr1_91104292_91104494	0.21	Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	6821	0.19
chr2_132638397_132638559	0.21	AU019990	expressed sequence AU019990	7403	0.13
chr12_79762583_79762777	0.20	9430078K24Rik	RIKEN cDNA 9430078K24 gene	162053	0.03
chr15_7160536_7160705	0.20	Lifr	LIF receptor alpha	6267	0.29
chr10_41805911_41806072	0.20	Cep57l1	centrosomal protein 57-like 1	3616	0.19
chr9_44639744_44640069	0.20	Gm47234	predicted gene, 47234	5711	0.08
chr15_67903084_67903264	0.20	Gm49408	predicted gene, 49408	29346	0.21
chr9_66733466_66733631	0.20	Car12	carbonic anhydrase 12	14162	0.17
chr1_73188866_73189036	0.19	Gm38106	predicted gene, 38106	20472	0.23
chr18_38777833_38778448	0.19	Gm8302	predicted gene 8302	5793	0.22
chr17_26087144_26087303	0.19	Decr2	2-4-dienoyl-Coenzyme A reductase 2, peroxisomal	1449	0.21
chr13_89791634_89791792	0.19	Vcan	versican	49204	0.15
chr8_91657490_91657652	0.19	Gm45295	predicted gene 45295	14326	0.12
chr10_107964145_107964306	0.19	Gm29685	predicted gene, 29685	17580	0.24
chr1_82168515_82168674	0.19	Mir6344	microRNA 6344	36678	0.16
chr12_79352651_79352859	0.19	Rad51b	RAD51 paralog B	25402	0.2
chr6_38737313_38737464	0.19	Hipk2	homeodomain interacting protein kinase 2	5872	0.25
chr4_35113350_35113823	0.19	Ifnk	interferon kappa	38470	0.14
chr4_152981027_152981202	0.18	Gm25779	predicted gene, 25779	32470	0.23
chr13_93177685_93177846	0.18	Tent2	terminal nucleotidyltransferase 2	9336	0.2
chr10_117703668_117703856	0.18	Mdm2	transformed mouse 3T3 cell double minute 2	6260	0.15
chr1_192392344_192392537	0.18	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	42300	0.19
chr6_28767893_28768066	0.18	Snd1	staphylococcal nuclease and tudor domain containing 1	3289	0.27
chr7_99156266_99156601	0.18	Dgat2	diacylglycerol O-acyltransferase 2	13673	0.12
chr10_99313401_99313555	0.18	B530045E10Rik	RIKEN cDNA B530045E10 gene	14312	0.14
chr6_129225478_129225648	0.18	2310001H17Rik	RIKEN cDNA 2310001H17 gene	8411	0.12
chr9_79467625_79467910	0.18	Gm10635	predicted gene 10635	51535	0.11
chr12_111603941_111604126	0.18	Mark3	MAP/microtubule affinity regulating kinase 3	478	0.7
chr6_93324004_93324164	0.18	Gm25094	predicted gene, 25094	11504	0.26
chr10_99257610_99257773	0.18	Dusp6	dual specificity phosphatase 6	5540	0.12
chr4_135859060_135859235	0.17	Srsf10	serine and arginine-rich splicing factor 10	2641	0.16
chr3_41154447_41154774	0.17	Gm40038	predicted gene, 40038	18053	0.21
chr5_67347155_67347319	0.17	Gm43698	predicted gene 43698	13150	0.16
chr16_71445241_71445456	0.17	4930567J20Rik	RIKEN cDNA 4930567J20 gene	195464	0.03
chr2_104813243_104813434	0.17	Qser1	glutamine and serine rich 1	3358	0.19
chr6_88744911_88745283	0.17	Gm43999	predicted gene, 43999	2370	0.19
chr2_119593833_119594019	0.17	Oip5os1	Opa interacting protein 5, opposite strand 1	371	0.78
chr19_37442522_37442707	0.17	Hhex	hematopoietically expressed homeobox	5875	0.13
chr3_121696912_121697098	0.17	Gm43608	predicted gene 43608	13241	0.11
chr7_87371467_87371654	0.17	Tyr	tyrosinase	121832	0.05
chr3_58659939_58660116	0.17	AU022133	expressed sequence AU022133	6539	0.13
chr8_40573020_40573204	0.17	Mtmr7	myotubularin related protein 7	17402	0.16
chr17_81703423_81703574	0.17	Slc8a1	solute carrier family 8 (sodium/calcium exchanger), member 1	33311	0.22
chr4_105149185_105149336	0.17	Plpp3	phospholipid phosphatase 3	8087	0.26
chr4_118437515_118437694	0.17	Cdc20	cell division cycle 20	252	0.84
chr17_86236900_86237066	0.17	2010106C02Rik	RIKEN cDNA 2010106C02 gene	50195	0.14
chr3_69354794_69354993	0.17	Gm17212	predicted gene 17212	19133	0.17
chr5_13345770_13345921	0.17	Sema3a	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A	50939	0.16
chr11_3397834_3397998	0.17	Limk2	LIM motif-containing protein kinase 2	11258	0.12
chr13_41112373_41112548	0.17	Gcm2	glial cells missing homolog 2	1425	0.28
chr3_157105884_157106045	0.17	Gm43526	predicted gene 43526	34220	0.18
chr3_138256816_138256967	0.17	Adh1	alcohol dehydrogenase 1 (class I)	4100	0.14
chr1_93439433_93439589	0.17	Hdlbp	high density lipoprotein (HDL) binding protein	1281	0.34
chr10_68120874_68121044	0.17	Arid5b	AT rich interactive domain 5B (MRF1-like)	15667	0.23
chr3_101805513_101805698	0.16	Mab21l3	mab-21-like 3	30618	0.17
chr4_82291564_82291726	0.16	n-R5s188	nuclear encoded rRNA 5S 188	147765	0.04
chr8_89234098_89234358	0.16	Gm5356	predicted pseudogene 5356	46668	0.18
chr3_81573214_81573380	0.16	Gm4857	predicted gene 4857	16472	0.28
chr10_91261452_91261622	0.16	Gm18705	predicted gene, 18705	2193	0.29
chr3_81289863_81290037	0.16	Gm37300	predicted gene, 37300	115622	0.06
chr10_18067829_18067983	0.16	Reps1	RalBP1 associated Eps domain containing protein	11902	0.2
chr1_91893698_91893865	0.16	Gm37600	predicted gene, 37600	22479	0.17
chr2_30409569_30409727	0.16	Crat	carnitine acetyltransferase	2969	0.13
chr15_27913676_27913865	0.16	Trio	triple functional domain (PTPRF interacting)	5501	0.24
chr15_81915764_81916002	0.16	Polr3h	polymerase (RNA) III (DNA directed) polypeptide H	754	0.45
chr8_45432180_45432331	0.16	Tlr3	toll-like receptor 3	21175	0.15
chr7_25450039_25450206	0.16	Gm15495	predicted gene 15495	6659	0.11
chr1_171212888_171213039	0.16	Nr1i3	nuclear receptor subfamily 1, group I, member 3	1007	0.29
chr10_17667448_17667608	0.16	Gm47771	predicted gene, 47771	9015	0.23
chr11_68540853_68541004	0.16	Pik3r6	phosphoinositide-3-kinase regulatory subunit 5	4728	0.19
chr15_6882256_6882435	0.16	Osmr	oncostatin M receptor	7376	0.29
chr3_89436835_89437052	0.16	Pbxip1	pre B cell leukemia transcription factor interacting protein 1	187	0.87
chrX_129167854_129168016	0.16	Gm26029	predicted gene, 26029	11050	0.3
chr19_53889732_53889907	0.15	Pdcd4	programmed cell death 4	2412	0.23
chr2_4941693_4941844	0.15	Gm13194	predicted gene 13194	406	0.76
chr15_31251286_31251565	0.15	Dap	death-associated protein	16911	0.15
chr6_87805806_87806031	0.15	9930120I10Rik	RIKEN cDNA 9930120I10 gene	418	0.64
chr6_49210657_49210827	0.15	Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3	3419	0.2
chr7_16046893_16047053	0.15	Bicra	BRD4 interacting chromatin remodeling complex associated protein	948	0.46
chr2_24183784_24184156	0.15	Il1f9	interleukin 1 family, member 9	2506	0.2
chr2_92943609_92943778	0.15	Syt13	synaptotagmin XIII	28595	0.15
chr4_132655416_132655575	0.15	Eya3	EYA transcriptional coactivator and phosphatase 3	1205	0.44
chr4_107388361_107388798	0.15	Ndc1	NDC1 transmembrane nucleoporin	7117	0.15
chr14_27679797_27679980	0.15	Erc2	ELKS/RAB6-interacting/CAST family member 2	27061	0.19
chr4_108066732_108066892	0.15	Scp2	sterol carrier protein 2, liver	4551	0.16
chr2_5219339_5219504	0.15	Gm23118	predicted gene, 23118	40694	0.14
chr10_128921362_128921572	0.15	Rdh5	retinol dehydrogenase 5	1421	0.19
chr4_124670340_124670505	0.15	Gm2164	predicted gene 2164	13253	0.09
chr16_97497728_97497915	0.15	Gm24777	predicted gene, 24777	1201	0.36
chr5_114122907_114123086	0.15	Alkbh2	alkB homolog 2, alpha-ketoglutarate-dependent dioxygenase	5180	0.11
chr6_120589309_120589479	0.15	Gm44124	predicted gene, 44124	9218	0.14
chr8_46404315_46404484	0.15	Gm45253	predicted gene 45253	18511	0.13
chr6_87427046_87427210	0.15	Bmp10	bone morphogenetic protein 10	1866	0.27
chr16_10347675_10347844	0.15	Gm1600	predicted gene 1600	168	0.94
chr6_94550970_94551136	0.15	Slc25a26	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26	16913	0.19
chr14_48072185_48072471	0.15	Gm6055	predicted gene 6055	7424	0.16
chr18_56974912_56975237	0.15	C330018D20Rik	RIKEN cDNA C330018D20 gene	172	0.96
chr15_34477411_34477563	0.15	Gm49188	predicted gene, 49188	4220	0.13
chr8_89097725_89097891	0.15	Gm6625	predicted gene 6625	49250	0.14
chr6_5223673_5223834	0.15	Gm44250	predicted gene, 44250	3267	0.22
chr5_25054101_25054285	0.15	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	46449	0.11
chr6_108435674_108435848	0.15	Itpr1	inositol 1,4,5-trisphosphate receptor 1	17884	0.19
chr4_44776736_44776900	0.15	Zcchc7	zinc finger, CCHC domain containing 7	16374	0.16
chr10_18370393_18370778	0.15	Nhsl1	NHS-like 1	19737	0.19
chr4_148602965_148603132	0.14	Masp2	mannan-binding lectin serine peptidase 2	473	0.67
chr13_108719037_108719229	0.14	Rps3a3	ribosomal protein S3A3	48530	0.17
chr6_142894834_142895115	0.14	St8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1	11934	0.19
chr10_87704249_87704407	0.14	Gm48195	predicted gene, 48195	15750	0.25
chr6_120190995_120191345	0.14	Ninj2	ninjurin 2	2653	0.29
chr10_61303355_61303525	0.14	Prf1	perforin 1 (pore forming protein)	3639	0.17
chr1_128158652_128158822	0.14	Gm37407	predicted gene, 37407	4477	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.3	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.2	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.2	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.1	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.1	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.1	GO:2000821	regulation of grooming behavior(GO:2000821)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0031915	positive regulation of synaptic plasticity(GO:0031915)
0.0	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.1	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0	0.1	GO:0072310	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0060837	blood vessel endothelial cell differentiation(GO:0060837)
0.0	0.0	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.1	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.0	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.0	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.0	GO:0006848	pyruvate transport(GO:0006848)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.0	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.0	0.0	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.0	GO:0060335	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.0	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.0	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.0	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.1	GO:0097427	microtubule bundle(GO:0097427)
0.1	GO:0097443	sorting endosome(GO:0097443)
0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	GO:0070876	SOSS complex(GO:0070876)
0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.1	GO:0019862	IgA binding(GO:0019862)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.3	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.1	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0	0.1	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.0	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0035276	ethanol binding(GO:0035276)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.0	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.0	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.0	GO:2001070	starch binding(GO:2001070)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.0	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport