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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Nr4a3

Z-value: 2.30

Motif logo

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Transcription factors associated with Nr4a3

Gene Symbol Gene ID Gene Info
Nr4a3
ENSMUSG00000028341.3 nuclear receptor subfamily 4, group A, member 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_48042684_48042844Nr4a323890.3387260.946.0e-03Click!
chr4_48046634_48046887Nr4a315290.4566510.882.1e-02Click!
chr4_48044008_48044162Nr4a310680.5833450.853.2e-02Click!
chr4_48045019_48045175Nr4a3560.9807030.805.6e-02Click!
chr4_48045892_48046043Nr4a37360.7214130.731.0e-01Click!

Activity of the Nr4a3 motif across conditions

Conditions sorted by the z-value of the Nr4a3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_125976536_125976742 2.25 Kcnk1
 potassium channel, subfamily K, member 1
 18531
 0.19
chr15_25435984_25436493 2.10 Gm48956
 predicted gene, 48956
 9402
 0.16
chr10_99600138_99600289 1.28 Gm20110
 predicted gene, 20110
 8958
 0.19
chr8_45691473_45691656 1.14 Sorbs2
 sorbin and SH3 domain containing 2
 3227
 0.28
chr8_123978504_123978907 1.09 Abcb10
 ATP-binding cassette, sub-family B (MDR/TAP), member 10
 4417
 0.12
chr6_119487729_119487894 1.05 Fbxl14
 F-box and leucine-rich repeat protein 14
 8143
 0.21
chr8_24506282_24506451 1.02 9130214F15Rik
 RIKEN cDNA 9130214F15 gene
 64
 0.97
chr5_93296317_93296483 1.02 Ccng2
 cyclin G2
 27692
 0.16
chr17_81389463_81389664 1.01 Gm50044
 predicted gene, 50044
 18730
 0.23
chr4_129191808_129191992 1.00 Yars
 tyrosyl-tRNA synthetase
 1998
 0.2
chr1_187313973_187314152 0.99 Gm38155
 predicted gene, 38155
 63407
 0.1
chr19_3650560_3650722 0.98 Lrp5
 low density lipoprotein receptor-related protein 5
 34849
 0.1
chr1_79466047_79466371 0.96 Scg2
 secretogranin II
 26089
 0.18
chr13_54583316_54583476 0.95 Arl10
 ADP-ribosylation factor-like 10
 4584
 0.11
chr9_122018172_122018323 0.94 Gm47117
 predicted gene, 47117
 6107
 0.11
chr3_100536474_100536643 0.94 Gm42868
 predicted gene 42868
 39129
 0.11
chr3_52646413_52646568 0.88 Gm10293
 predicted pseudogene 10293
 33655
 0.18
chr16_34746212_34746363 0.82 Mylk
 myosin, light polypeptide kinase
 1077
 0.6
chr12_26387378_26387859 0.82 Rnf144a
 ring finger protein 144A
 18829
 0.15
chr5_145864595_145865130 0.81 Cyp3a11
 cytochrome P450, family 3, subfamily a, polypeptide 11
 11829
 0.16
chr4_134722177_134722332 0.81 Man1c1
 mannosidase, alpha, class 1C, member 1
 17964
 0.18
chr14_51289185_51289366 0.81 Gm49245
 predicted gene, 49245
 11673
 0.1
chr8_117637336_117637505 0.81 Sdr42e1
 short chain dehydrogenase/reductase family 42E, member 1
 34127
 0.12
chr6_6183421_6183599 0.80 Slc25a13
 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
 7809
 0.26
chr9_65191450_65191617 0.80 Parp16
 poly (ADP-ribose) polymerase family, member 16
 3820
 0.14
chr2_167877367_167877523 0.80 Gm14319
 predicted gene 14319
 18860
 0.16
chr1_179632334_179632515 0.78 Sccpdh
 saccharopine dehydrogenase (putative)
 35786
 0.14
chr8_127515714_127515885 0.76 Gm6921
 predicted pseudogene 6921
 45636
 0.17
chr2_163598624_163598794 0.76 Ttpal
 tocopherol (alpha) transfer protein-like
 3605
 0.18
chrX_85053601_85053753 0.75 Dmd
 dystrophin, muscular dystrophy
 5264
 0.33
chr10_75033725_75033908 0.74 Gm40692
 predicted gene, 40692
 529
 0.63
chr3_85273227_85273668 0.73 1700036G14Rik
 RIKEN cDNA 1700036G14 gene
 44072
 0.16
chr5_56910070_56910250 0.73 Gm23896
 predicted gene, 23896
 174070
 0.03
chr18_20936854_20937178 0.73 Rnf125
 ring finger protein 125
 7609
 0.22
chr10_42194110_42194261 0.72 Foxo3
 forkhead box O3
 64181
 0.12
chr16_79059250_79059443 0.72 Tmprss15
 transmembrane protease, serine 15
 31746
 0.22
chr12_29257874_29258025 0.72 Gm6989
 predicted gene 6989
 59619
 0.14
chr6_62934342_62934493 0.72 Gm5001
 predicted gene 5001
 5271
 0.31
chr7_24504957_24505109 0.71 Zfp428
 zinc finger protein 428
 1973
 0.15
chr4_145279031_145279214 0.71 Tnfrsf1b
 tumor necrosis factor receptor superfamily, member 1b
 32252
 0.14
chr2_163616887_163617081 0.70 Ttpal
 tocopherol (alpha) transfer protein-like
 5464
 0.15
chr10_60733446_60733765 0.69 Slc29a3
 solute carrier family 29 (nucleoside transporters), member 3
 9289
 0.21
chr14_19710131_19710282 0.69 Gm49341
 predicted gene, 49341
 12997
 0.13
chr4_135746130_135746372 0.69 Gm12988
 predicted gene 12988
 10444
 0.12
chr1_36525855_36526032 0.69 Gm38033
 predicted gene, 38033
 2294
 0.14
chr10_84907603_84907783 0.69 Ric8b
 RIC8 guanine nucleotide exchange factor B
 9923
 0.24
chr14_66521966_66522122 0.68 Gm23899
 predicted gene, 23899
 69651
 0.11
chr10_79616142_79616293 0.68 C2cd4c
 C2 calcium-dependent domain containing 4C
 2192
 0.15
chr1_51996762_51997232 0.68 Stat4
 signal transducer and activator of transcription 4
 9849
 0.17
chr5_90894238_90894431 0.67 Gm22816
 predicted gene, 22816
 954
 0.41
chr14_25295396_25295547 0.67 Gm26660
 predicted gene, 26660
 83164
 0.08
chr19_30171407_30171581 0.67 Gldc
 glycine decarboxylase
 3935
 0.23
chr18_15330500_15330684 0.65 E430002N23Rik
 RIKEN cDNA E430002N23 gene
 17893
 0.18
chr2_166637694_166637887 0.65 Prex1
 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
 1178
 0.52
chr17_45322333_45322491 0.64 Cdc5l
 cell division cycle 5-like (S. pombe)
 93272
 0.06
chr8_25819139_25819316 0.64 Ash2l
 ASH2 like histone lysine methyltransferase complex subunit
 4348
 0.13
chr5_76297411_76297591 0.64 Gm43658
 predicted gene 43658
 4274
 0.14
chr2_33369566_33369732 0.64 Ralgps1
 Ral GEF with PH domain and SH3 binding motif 1
 1780
 0.3
chr19_5880801_5880961 0.64 Slc25a45
 solute carrier family 25, member 45
 2225
 0.13
chr3_18463182_18463725 0.63 Gm30667
 predicted gene, 30667
 2199
 0.33
chr1_133933859_133934320 0.62 Prelp
 proline arginine-rich end leucine-rich repeat
 12675
 0.13
chr15_102177030_102177199 0.62 Csad
 cysteine sulfinic acid decarboxylase
 1905
 0.2
chr10_28166717_28166892 0.61 Gm22370
 predicted gene, 22370
 47317
 0.17
chr8_103417794_103417953 0.61 1600027J07Rik
 RIKEN cDNA 1600027J07 gene
 70339
 0.12
chr13_114974629_114975014 0.61 Gm47776
 predicted gene, 47776
 39753
 0.15
chr13_56477354_56477672 0.60 Il9
 interleukin 9
 4733
 0.19
chr6_136469608_136469798 0.60 Gm6728
 predicted gene 6728
 17483
 0.12
chr11_5917118_5917412 0.60 Gm11967
 predicted gene 11967
 1950
 0.2
chr1_134293960_134294142 0.60 Myog
 myogenin
 4062
 0.15
chr1_155158041_155158192 0.60 Stx6
 syntaxin 6
 599
 0.68
chr15_96031527_96031698 0.59 D030018L15Rik
 RIKEN cDNA D030018L15 gene
 23213
 0.19
chr16_91833643_91834213 0.59 Itsn1
 intersectin 1 (SH3 domain protein 1A)
 5771
 0.19
chr12_41208691_41208865 0.59 Gm47376
 predicted gene, 47376
 139312
 0.04
chr19_4700355_4700506 0.59 Gm960
 predicted gene 960
 1762
 0.22
chr16_95673938_95674224 0.58 Ets2
 E26 avian leukemia oncogene 2, 3' domain
 27994
 0.19
chr7_109599227_109599378 0.58 Denn2b
 DENN domain containing 2B
 3363
 0.22
chr10_81417531_81417694 0.57 Mir1191b
 microRNA 1191b
 1315
 0.18
chr1_130763367_130763536 0.57 Gm28856
 predicted gene 28856
 2933
 0.14
chr8_84069298_84069478 0.57 C330011M18Rik
 RIKEN cDNA C330011M18 gene
 2101
 0.12
chr5_92134368_92134534 0.56 Uso1
 USO1 vesicle docking factor
 3487
 0.15
chr19_5567308_5567477 0.56 Ap5b1
 adaptor-related protein complex 5, beta 1 subunit
 633
 0.46
chr18_31966444_31966632 0.56 Lims2
 LIM and senescent cell antigen like domains 2
 10205
 0.13
chr2_118883051_118883401 0.55 Ivd
 isovaleryl coenzyme A dehydrogenase
 6793
 0.14
chr9_77847197_77847348 0.55 Gm19572
 predicted gene, 19572
 4436
 0.16
chr11_26592820_26593046 0.54 Gm6899
 predicted gene 6899
 293
 0.76
chr2_167799424_167799897 0.54 9230111E07Rik
 RIKEN cDNA 9230111E07 gene
 17607
 0.14
chr1_73901414_73901565 0.54 Tns1
 tensin 1
 26728
 0.15
chr1_156074597_156074881 0.54 Tor1aip2
 torsin A interacting protein 2
 11526
 0.17
chr13_14191910_14192117 0.54 Arid4b
 AT rich interactive domain 4B (RBP1-like)
 836
 0.59
chr5_115475861_115476388 0.54 Sirt4
 sirtuin 4
 3814
 0.1
chr8_25750561_25750717 0.54 Ddhd2
 DDHD domain containing 2
 789
 0.44
chr12_59191626_59191786 0.53 Mia2
 MIA SH3 domain ER export factor 2
 12193
 0.14
chr5_140171802_140172150 0.53 Mad1l1
 MAD1 mitotic arrest deficient 1-like 1
 2683
 0.24
chr11_97836691_97836945 0.53 Lasp1
 LIM and SH3 protein 1
 3394
 0.12
chr13_43252482_43252652 0.53 Gfod1
 glucose-fructose oxidoreductase domain containing 1
 50838
 0.13
chr4_124737570_124737747 0.52 Gm24721
 predicted gene, 24721
 1819
 0.16
chr10_43487752_43488061 0.52 Bend3
 BEN domain containing 3
 2672
 0.19
chr11_117780625_117780787 0.52 Tmc6
 transmembrane channel-like gene family 6
 48
 0.93
chr4_150732960_150733140 0.52 Gm16079
 predicted gene 16079
 54258
 0.11
chr19_6251158_6251334 0.52 Atg2a
 autophagy related 2A
 242
 0.81
chr1_62709908_62710059 0.52 Nrp2
 neuropilin 2
 6281
 0.18
chr13_54439539_54439690 0.52 Thoc3
 THO complex 3
 29174
 0.12
chr18_35256811_35256978 0.51 Ctnna1
 catenin (cadherin associated protein), alpha 1
 4573
 0.19
chr9_111440393_111440743 0.51 Dclk3
 doublecortin-like kinase 3
 1487
 0.42
chr16_3843876_3844135 0.51 Zfp174
 zinc finger protein 174
 3263
 0.13
chr11_83850528_83850683 0.51 Hnf1b
 HNF1 homeobox B
 250
 0.85
chr2_160805166_160805505 0.51 Gm11447
 predicted gene 11447
 40278
 0.11
chr11_78972853_78973033 0.51 Lgals9
 lectin, galactose binding, soluble 9
 2613
 0.27
chr1_153307781_153308161 0.50 Gm8818
 predicted pseudogene 8818
 2539
 0.25
chr2_25708935_25709097 0.49 A230005M16Rik
 RIKEN cDNA A230005M16 gene
 700
 0.42
chr4_144957863_144958036 0.49 Gm38074
 predicted gene, 38074
 899
 0.6
chr19_33098081_33098289 0.49 Gm29946
 predicted gene, 29946
 24462
 0.18
chr19_40218990_40219184 0.49 Pdlim1
 PDZ and LIM domain 1 (elfin)
 4269
 0.17
chr2_43513507_43513674 0.48 Gm13464
 predicted gene 13464
 5808
 0.3
chr6_39796421_39796591 0.48 Mrps33
 mitochondrial ribosomal protein S33
 9536
 0.17
chr2_166678201_166678352 0.48 Gm23152
 predicted gene, 23152
 23134
 0.17
chr10_84477716_84477877 0.48 4930463O16Rik
 RIKEN cDNA 4930463O16 gene
 10497
 0.12
chr19_38709785_38709951 0.47 Gm8717
 predicted gene 8717
 5544
 0.21
chr11_88574733_88574900 0.47 Msi2
 musashi RNA-binding protein 2
 15331
 0.24
chrX_160424988_160425139 0.47 Adgrg2
 adhesion G protein-coupled receptor G2
 2229
 0.34
chr17_26702508_26702992 0.47 Crebrf
 CREB3 regulatory factor
 12900
 0.14
chr3_52469938_52470147 0.47 Gm38098
 predicted gene, 38098
 44634
 0.14
chr3_69543290_69543467 0.47 Ppm1l
 protein phosphatase 1 (formerly 2C)-like
 946
 0.58
chr18_4956609_4956805 0.47 Svil
 supervillin
 34981
 0.22
chr14_100224229_100224566 0.46 Gm16260
 predicted gene 16260
 4911
 0.22
chr4_154247269_154247441 0.46 Megf6
 multiple EGF-like-domains 6
 1941
 0.28
chr1_121321522_121321673 0.46 Insig2
 insulin induced gene 2
 1594
 0.33
chr1_157084475_157084641 0.46 Tex35
 testis expressed 35
 23830
 0.14
chr6_71989276_71989427 0.46 Gm26628
 predicted gene, 26628
 25576
 0.11
chr13_46161900_46162051 0.46 Gm10113
 predicted gene 10113
 29071
 0.21
chr3_10282975_10283159 0.45 Fabp12
 fatty acid binding protein 12
 18107
 0.09
chr3_104568490_104568648 0.45 Gm26091
 predicted gene, 26091
 32670
 0.1
chr1_118448989_118449484 0.45 Gm26080
 predicted gene, 26080
 4249
 0.15
chr2_34486208_34486368 0.45 Mapkap1
 mitogen-activated protein kinase associated protein 1
 41941
 0.13
chr1_91899152_91899309 0.45 Gm37600
 predicted gene, 37600
 17030
 0.18
chr1_91095685_91095922 0.45 Lrrfip1
 leucine rich repeat (in FLII) interacting protein 1
 15411
 0.18
chr1_20618287_20618471 0.45 Pkhd1
 polycystic kidney and hepatic disease 1
 315
 0.9
chr2_173162438_173162602 0.44 Pck1
 phosphoenolpyruvate carboxykinase 1, cytosolic
 9438
 0.17
chr7_102132512_102132682 0.44 Chrna10
 cholinergic receptor, nicotinic, alpha polypeptide 10
 15769
 0.1
chr12_80126455_80126626 0.44 2310015A10Rik
 RIKEN cDNA 2310015A10 gene
 5401
 0.14
chr4_15327477_15327645 0.44 Gm24317
 predicted gene, 24317
 55587
 0.13
chr19_10041963_10042141 0.44 Fads3
 fatty acid desaturase 3
 320
 0.83
chr6_119681588_119681760 0.43 Erc1
 ELKS/RAB6-interacting/CAST family member 1
 59569
 0.13
chr6_72604103_72604254 0.43 Retsat
 retinol saturase (all trans retinol 13,14 reductase)
 195
 0.84
chr11_46084943_46085145 0.43 Mir8100
 microRNA 8100
 17226
 0.12
chr16_10981270_10981624 0.43 Litaf
 LPS-induced TN factor
 5868
 0.12
chr7_134192391_134192592 0.43 Adam12
 a disintegrin and metallopeptidase domain 12 (meltrin alpha)
 19547
 0.21
chr17_68285429_68285617 0.43 L3mbtl4
 L3MBTL4 histone methyl-lysine binding protein
 11726
 0.26
chr17_65931229_65931442 0.43 Twsg1
 twisted gastrulation BMP signaling modulator 1
 4926
 0.15
chr3_100189024_100189191 0.43 Gdap2
 ganglioside-induced differentiation-associated-protein 2
 5473
 0.23
chr9_108858778_108859092 0.43 Slc26a6
 solute carrier family 26, member 6
 3273
 0.12
chr1_59157472_59157626 0.43 Mpp4
 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
 1112
 0.34
chr1_182125404_182125574 0.43 Srp9
 signal recognition particle 9
 708
 0.61
chr6_99666342_99666493 0.43 Eif4e3
 eukaryotic translation initiation factor 4E member 3
 354
 0.48
chr3_145561026_145561180 0.42 Znhit6
 zinc finger, HIT type 6
 15102
 0.19
chr4_136018964_136019115 0.42 Gm24362
 predicted gene, 24362
 553
 0.57
chr7_100077379_100077530 0.42 Pold3
 polymerase (DNA-directed), delta 3, accessory subunit
 12583
 0.16
chr18_57029725_57029909 0.42 C330018D20Rik
 RIKEN cDNA C330018D20 gene
 54449
 0.12
chr5_140107803_140107986 0.41 Gm16121
 predicted gene 16121
 6695
 0.16
chr4_89526966_89527117 0.41 Gm12608
 predicted gene 12608
 82397
 0.09
chr11_94158519_94158921 0.41 B230206L02Rik
 RIKEN cDNA B230206L02 gene
 23060
 0.17
chr10_59784742_59784904 0.41 Gm17059
 predicted gene 17059
 15431
 0.14
chr3_130692655_130693111 0.41 Ostc
 oligosaccharyltransferase complex subunit (non-catalytic)
 3739
 0.17
chr7_45973330_45973912 0.41 Abcc6
 ATP-binding cassette, sub-family C (CFTR/MRP), member 6
 302
 0.76
chr2_169075125_169075304 0.40 Gm26469
 predicted gene, 26469
 14094
 0.19
chr15_88830094_88830418 0.40 Gm23144
 predicted gene, 23144
 5044
 0.15
chr12_29136516_29136667 0.40 Gm31333
 predicted gene, 31333
 2576
 0.33
chr4_145054462_145054637 0.40 Vps13d
 vacuolar protein sorting 13D
 406
 0.89
chr6_17469322_17469539 0.40 Met
 met proto-oncogene
 5323
 0.23
chr9_46238922_46239117 0.40 Apoa4
 apolipoprotein A-IV
 1677
 0.17
chr10_99207689_99207863 0.40 Poc1b
 POC1 centriolar protein B
 14884
 0.11
chr17_11752805_11752972 0.40 Gm10513
 predicted gene 10513
 20543
 0.26
chr15_81337946_81338137 0.40 Slc25a17
 solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
 6116
 0.16
chr7_136883017_136883173 0.40 Mgmt
 O-6-methylguanine-DNA methyltransferase
 11519
 0.23
chr9_88355859_88356010 0.40 Nt5e
 5' nucleotidase, ecto
 247
 0.9
chr6_37592493_37592657 0.40 Gm7463
 predicted gene 7463
 51161
 0.14
chrX_7766214_7766424 0.39 Tfe3
 transcription factor E3
 1667
 0.18
chr8_10914649_10914809 0.39 3930402G23Rik
 RIKEN cDNA 3930402G23 gene
 13715
 0.09
chr15_82165521_82165825 0.39 Srebf2
 sterol regulatory element binding factor 2
 17648
 0.09
chr16_23108839_23109021 0.39 Snord2
 small nucleolar RNA, C/D box 2
 23
 0.76
chr3_87030981_87031137 0.39 Gm8869
 predicted gene 8869
 7176
 0.14
chr7_143498695_143498856 0.38 Phlda2
 pleckstrin homology like domain, family A, member 2
 3766
 0.14
chr5_73264643_73264803 0.38 Gm34411
 predicted gene, 34411
 1294
 0.28
chr18_65097598_65097767 0.38 Nedd4l
 neural precursor cell expressed, developmentally down-regulated gene 4-like
 14628
 0.23
chr19_46714979_46715130 0.38 As3mt
 arsenic (+3 oxidation state) methyltransferase
 3082
 0.19
chr5_53078478_53078847 0.38 Slc34a2
 solute carrier family 34 (sodium phosphate), member 2
 29309
 0.14
chr4_58546190_58546357 0.38 Lpar1
 lysophosphatidic acid receptor 1
 2128
 0.33
chr9_63668708_63668859 0.38 Smad3
 SMAD family member 3
 2236
 0.33
chr7_14425285_14425519 0.38 Sult2a8
 sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8
 11045
 0.16
chr6_99271808_99271987 0.38 Foxp1
 forkhead box P1
 5365
 0.31
chr3_37634750_37634916 0.38 Spry1
 sprouty RTK signaling antagonist 1
 5114
 0.12
chr15_27525366_27525772 0.38 B230362B09Rik
 RIKEN cDNA B230362B09 gene
 21657
 0.15
chr1_190156610_190156822 0.38 Gm28172
 predicted gene 28172
 11954
 0.18
chr5_96458803_96458986 0.38 Gm33050
 predicted gene, 33050
 1151
 0.56
chr2_44920626_44920948 0.37 Gtdc1
 glycosyltransferase-like domain containing 1
 6362
 0.29
chr8_126723593_126723744 0.37 Gm45805
 predicted gene 45805
 34666
 0.19
chr6_128333409_128333573 0.37 Tulp3
 tubby-like protein 3
 7944
 0.07
chr11_109478088_109478523 0.37 Slc16a6
 solute carrier family 16 (monocarboxylic acid transporters), member 6
 4707
 0.13
chr18_75891950_75892137 0.37 Zbtb7c
 zinc finger and BTB domain containing 7C
 71828
 0.11
chr14_54723804_54723977 0.37 Cebpe
 CCAAT/enhancer binding protein (C/EBP), epsilon
 11716
 0.09

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0035865 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1 0.4 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.4 GO:0072180 mesonephric duct morphogenesis(GO:0072180)
0.1 0.4 GO:0009169 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.1 0.4 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.1 0.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.2 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.2 GO:0043465 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.1 0.4 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.1 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.2 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.0 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.1 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.2 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.3 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0052422 modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.4 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.2 GO:0060297 regulation of sarcomere organization(GO:0060297)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0 0.1 GO:0014735 regulation of muscle atrophy(GO:0014735)
0.0 0.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.2 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.1 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0001996 positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.1 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0 0.1 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.1 GO:1990791 dorsal root ganglion development(GO:1990791)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.1 GO:0071680 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.0 GO:2001046 positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.0 0.0 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.0 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.2 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.6 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0 0.0 GO:0032484 Ral protein signal transduction(GO:0032484)
0.0 0.0 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0009629 response to gravity(GO:0009629)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.0 0.1 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0036295 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.0 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.0 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.2 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 0.3 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.0 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0042045 epithelial fluid transport(GO:0042045)
0.0 0.2 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.1 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.2 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.0 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.0 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0 0.1 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.0 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0042574 retinal metabolic process(GO:0042574)
0.0 0.1 GO:0036089 cleavage furrow formation(GO:0036089)
0.0 0.0 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.0 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0006007 glucose catabolic process(GO:0006007)
0.0 0.2 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0051352 negative regulation of ligase activity(GO:0051352)
0.0 0.0 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.0 GO:0033505 floor plate morphogenesis(GO:0033505)
0.0 0.3 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.1 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.1 GO:0021999 neural plate anterior/posterior regionalization(GO:0021999)
0.0 0.4 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.0 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.0 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.2 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.0 GO:0042628 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.0 0.0 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.0 GO:0010288 response to lead ion(GO:0010288)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.0 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.1 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.0 GO:0015888 thiamine transport(GO:0015888)
0.0 0.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.0 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.0 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:0014858 positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0 0.1 GO:0033127 regulation of histone phosphorylation(GO:0033127)
0.0 0.0 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.0 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.0 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.0 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.0 0.1 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.0 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.1 GO:0098814 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.0 GO:0030202 heparin metabolic process(GO:0030202)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.0 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.2 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.0 GO:0046077 dUDP biosynthetic process(GO:0006227) dTTP biosynthetic process(GO:0006235) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075) dUDP metabolic process(GO:0046077)
0.0 0.1 GO:0016572 histone phosphorylation(GO:0016572)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0036336 dendritic cell migration(GO:0036336)
0.0 0.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.0 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.0 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.2 GO:0033622 integrin activation(GO:0033622)
0.0 0.1 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.0 GO:0001757 somite specification(GO:0001757)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.0 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.0 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0050957 equilibrioception(GO:0050957)
0.0 0.0 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.0 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.2 GO:0052696 flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.0 0.1 GO:0015846 polyamine transport(GO:0015846) polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.0 0.0 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.0 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.0 0.0 GO:0070384 Harderian gland development(GO:0070384)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0046691 intracellular canaliculus(GO:0046691)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.1 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.1 GO:0001939 female pronucleus(GO:0001939)
0.0 0.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.4 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.0 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.0 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0031430 M band(GO:0031430)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.1 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.3 GO:0002134 UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.2 GO:0004083 bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.2 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.1 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0038100 nodal binding(GO:0038100)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.4 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.5 GO:0022842 leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.2 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634)
0.0 0.1 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.3 GO:0097506 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.0 GO:0034416 bisphosphoglycerate phosphatase activity(GO:0034416)
0.0 0.1 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.1 GO:0005347 ATP transmembrane transporter activity(GO:0005347)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.3 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.1 GO:0034618 arginine binding(GO:0034618)
0.0 0.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.0 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.1 GO:0015254 glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.0 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.0 GO:0009041 uridylate kinase activity(GO:0009041)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.1 GO:0035671 enone reductase activity(GO:0035671)
0.0 0.1 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.0 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.2 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.0 GO:0032558 adenyl deoxyribonucleotide binding(GO:0032558)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0004739 pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.7 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.0 GO:0004487 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.3 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.1 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID AURORA B PATHWAY Aurora B signaling
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.0 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.2 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID GLYPICAN 1PATHWAY Glypican 1 network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.5 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.9 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.2 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.1 REACTOME LIPOPROTEIN METABOLISM Genes involved in Lipoprotein metabolism
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels