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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Otx1

Z-value: 1.85

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Transcription factors associated with Otx1

Gene Symbol	Gene ID	Gene Info
Otx1 Ensembl NCBI MGI UniProt	ENSMUSG00000005917.9	orthodenticle homeobox 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr11_21994002_21994316	Otx1	7456	0.251437	0.75	8.3e-02	Click!
chr11_22003047_22003450	Otx1	351	0.912755	0.73	9.6e-02	Click!
chr11_21993820_21993971	Otx1	7720	0.249976	0.68	1.4e-01	Click!

Activity of the Otx1 motif across conditions

Conditions sorted by the z-value of the Otx1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_21250942_21251436	2.00	Gsta3	glutathione S-transferase, alpha 3	2332	0.18
chr1_102517902_102518283	1.26	Gm20281	predicted gene, 20281	59170	0.14
chr1_51770461_51770858	1.19	Myo1b	myosin IB	220	0.94
chr1_140421414_140421565	1.14	Kcnt2	potassium channel, subfamily T, member 2	21447	0.27
chr2_167353709_167353860	1.13	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	4601	0.22
chr14_29030075_29030239	1.02	Lrtm1	leucine-rich repeats and transmembrane domains 1	9285	0.2
chr15_3500848_3501048	1.02	Ghr	growth hormone receptor	29304	0.23
chr9_69174629_69175249	0.95	Rora	RAR-related orphan receptor alpha	20602	0.27
chr7_30600397_30600564	0.82	Zbtb32	zinc finger and BTB domain containing 32	1571	0.14
chr11_61355295_61355921	0.82	Slc47a1	solute carrier family 47, member 1	10044	0.13
chr3_121440956_121441107	0.81	Cnn3	calponin 3, acidic	8735	0.14
chr4_136249531_136249688	0.78	Tcea3	transcription elongation factor A (SII), 3	1636	0.31
chr18_36656725_36657021	0.75	Ankhd1	ankyrin repeat and KH domain containing 1	1363	0.23
chr12_57281727_57281906	0.72	Mipol1	mirror-image polydactyly 1	357	0.88
chr14_58167012_58167201	0.70	Gm17109	predicted gene 17109	60977	0.11
chr5_72948525_72948751	0.68	Slain2	SLAIN motif family, member 2	139	0.94
chr3_115822314_115822536	0.68	Dph5	diphthamide biosynthesis 5	65412	0.08
chr16_79086922_79087073	0.68	Tmprss15	transmembrane protease, serine 15	4095	0.35
chr5_122938223_122938374	0.67	Kdm2b	lysine (K)-specific demethylase 2B	9696	0.13
chr18_38370754_38370932	0.66	Gm4949	predicted gene 4949	10305	0.12
chr13_95810879_95811051	0.65	Iqgap2	IQ motif containing GTPase activating protein 2	46568	0.13
chr5_132547259_132547410	0.65	Gm42626	predicted gene 42626	1278	0.33
chr10_4737716_4737877	0.65	Esr1	estrogen receptor 1 (alpha)	25145	0.25
chr10_68125559_68125710	0.63	Arid5b	AT rich interactive domain 5B (MRF1-like)	10992	0.25
chr15_35876710_35876861	0.63	Vps13b	vacuolar protein sorting 13B	5063	0.18
chr1_160280517_160280905	0.62	Rabgap1l	RAB GTPase activating protein 1-like	6627	0.14
chr5_100377737_100377909	0.62	Sec31a	Sec31 homolog A (S. cerevisiae)	1090	0.47
chr8_93190132_93190283	0.62	Gm45909	predicted gene 45909	1151	0.39
chr3_119995869_119996026	0.61	Gm18384	predicted gene, 18384	27216	0.24
chr3_135450666_135450817	0.61	Ube2d3	ubiquitin-conjugating enzyme E2D 3	3885	0.13
chr2_94044517_94044668	0.60	Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	21877	0.15
chr1_66816824_66817235	0.60	Kansl1l	KAT8 regulatory NSL complex subunit 1-like	517	0.58
chr13_102570134_102570306	0.59	Gm29927	predicted gene, 29927	20065	0.22
chr9_101114305_101114456	0.59	Gm37962	predicted gene, 37962	575	0.6
chr3_98644806_98645013	0.59	Hsd3b5	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5	14657	0.13
chr11_28694681_28694832	0.58	2810471M01Rik	RIKEN cDNA 2810471M01 gene	13192	0.17
chr18_16807706_16808293	0.58	Cdh2	cadherin 2	463	0.83
chr1_172861920_172862092	0.58	9430083B18Rik	RIKEN cDNA 9430083B18 gene	11545	0.15
chr19_47168542_47168771	0.58	H1f11-ps	H1.11 linker histone, pseudogene	2478	0.15
chr11_120238015_120238347	0.57	Bahcc1	BAH domain and coiled-coil containing 1	1482	0.22
chr10_69211873_69212406	0.56	Rhobtb1	Rho-related BTB domain containing 1	495	0.66
chr4_59006947_59007116	0.56	Gm20503	predicted gene 20503	3821	0.16
chr8_67495712_67495876	0.56	Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	846	0.56
chr1_58624556_58624707	0.56	Gm29389	predicted gene 29389	934	0.42
chr4_6225587_6225787	0.55	Ubxn2b	UBX domain protein 2B	34589	0.15
chr2_38823122_38823325	0.54	Nr6a1os	nuclear receptor subfamily 6, group A, member 1, opposite strand	34	0.96
chr4_97789633_97790009	0.54	E130114P18Rik	RIKEN cDNA E130114P18 gene	11743	0.2
chr1_131917786_131918076	0.54	Gm38067	predicted gene, 38067	3402	0.14
chr6_90499813_90499975	0.53	Gm44236	predicted gene, 44236	13408	0.1
chr16_76330855_76331006	0.53	Nrip1	nuclear receptor interacting protein 1	7272	0.24
chr15_59044746_59044952	0.53	Mtss1	MTSS I-BAR domain containing 1	4252	0.26
chr13_63665698_63665976	0.53	Gm47387	predicted gene, 47387	4040	0.18
chr13_42276666_42276839	0.52	Edn1	endothelin 1	24724	0.2
chr9_9145311_9145549	0.52	Gm16833	predicted gene, 16833	90858	0.08
chr2_52615496_52615707	0.51	Bloc1s2-ps	biogenesis of lysosomal organelles complex-1, subunit 2, pseudogene	4153	0.26
chr4_126967080_126967454	0.51	Zmym4	zinc finger, MYM-type 4	632	0.66
chr18_9781858_9782042	0.51	Gm23350	predicted gene, 23350	18688	0.12
chr4_6272645_6273060	0.50	Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	2779	0.27
chr18_60735828_60736023	0.50	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	2775	0.22
chr18_36725667_36726187	0.50	Cd14	CD14 antigen	811	0.38
chr17_25861995_25862180	0.50	Wdr90	WD repeat domain 90	586	0.4
chr19_44294561_44294712	0.50	Scd2	stearoyl-Coenzyme A desaturase 2	560	0.63
chr14_73524341_73524492	0.50	Nudt15	nudix (nucleoside diphosphate linked moiety X)-type motif 15	795	0.42
chr4_97783948_97784158	0.50	E130114P18Rik	RIKEN cDNA E130114P18 gene	5975	0.21
chr2_13371545_13371696	0.49	Cubn	cubilin (intrinsic factor-cobalamin receptor)	84007	0.08
chr4_76942079_76942249	0.49	Gm11246	predicted gene 11246	14853	0.22
chr11_45864290_45864443	0.49	Clint1	clathrin interactor 1	12402	0.15
chr12_59194644_59194808	0.49	Fbxo33	F-box protein 33	9710	0.14
chr9_122353524_122353735	0.49	Abhd5	abhydrolase domain containing 5	1840	0.27
chr4_130721540_130721691	0.48	Snord85	small nucleolar RNA, C/D box 85	28019	0.12
chr3_31970158_31970309	0.48	Gm37834	predicted gene, 37834	15469	0.27
chr2_148018621_148018772	0.48	9030622O22Rik	RIKEN cDNA 9030622O22 gene	19574	0.17
chr8_105122450_105122610	0.48	Ces4a	carboxylesterase 4A	9270	0.1
chr4_137925966_137926138	0.48	Ece1	endothelin converting enzyme 1	12370	0.21
chr9_53351302_53351453	0.47	Exph5	exophilin 5	10188	0.17
chr7_67658992_67659201	0.47	Ttc23	tetratricopeptide repeat domain 23	3649	0.17
chr13_44735230_44735426	0.47	Jarid2	jumonji, AT rich interactive domain 2	1288	0.56
chr4_134993702_134994076	0.47	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	62879	0.09
chr16_38096839_38096998	0.47	Gsk3b	glycogen synthase kinase 3 beta	6630	0.23
chr8_80982572_80982735	0.46	Gm9725	predicted gene 9725	30923	0.13
chr3_136048376_136048532	0.46	Gm5281	predicted gene 5281	3234	0.26
chr15_55043394_55043818	0.46	Taf2	TATA-box binding protein associated factor 2	2560	0.24
chr10_77587179_77587612	0.46	Pttg1ip	pituitary tumor-transforming 1 interacting protein	1999	0.18
chr2_78656286_78656827	0.46	Gm14463	predicted gene 14463	873	0.71
chr3_84258598_84259173	0.46	Trim2	tripartite motif-containing 2	484	0.86
chr9_66589937_66590103	0.45	Usp3	ubiquitin specific peptidase 3	2938	0.26
chr18_61841168_61841343	0.45	Afap1l1	actin filament associated protein 1-like 1	54553	0.1
chr6_149170663_149170967	0.45	Amn1	antagonist of mitotic exit network 1	2556	0.21
chrX_166475448_166475748	0.45	Rab9	RAB9, member RAS oncogene family	163	0.93
chr2_81270139_81270299	0.45	Gm23900	predicted gene, 23900	273123	0.01
chr15_33327562_33327727	0.44	1700084J12Rik	RIKEN cDNA 1700084J12 gene	78295	0.11
chr2_160805916_160806220	0.44	Gm11447	predicted gene 11447	39545	0.11
chr2_77541490_77541687	0.44	Zfp385b	zinc finger protein 385B	20392	0.25
chr19_55260197_55260377	0.44	Acsl5	acyl-CoA synthetase long-chain family member 5	6918	0.18
chr10_14977642_14977816	0.44	Gm23892	predicted gene, 23892	6941	0.26
chr6_108098759_108098943	0.44	Sumf1	sulfatase modifying factor 1	28212	0.17
chr12_75566070_75566284	0.44	Gm47689	predicted gene, 47689	13688	0.18
chr4_62505920_62506071	0.44	Hdhd3	haloacid dehalogenase-like hydrolase domain containing 3	2528	0.17
chr6_24207508_24207678	0.44	Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	39501	0.17
chr7_99102056_99102229	0.44	Uvrag	UV radiation resistance associated gene	2715	0.21
chr9_58558152_58558318	0.44	Cd276	CD276 antigen	2798	0.22
chr1_151135112_151135579	0.44	Gm8941	predicted gene 8941	1162	0.35
chr13_120027109_120027394	0.44	Gm36079	predicted gene, 36079	240	0.84
chr13_58274234_58274655	0.43	Gkap1	G kinase anchoring protein 1	256	0.86
chr8_36265736_36265923	0.43	Lonrf1	LON peptidase N-terminal domain and ring finger 1	16313	0.2
chr16_30027841_30027992	0.43	9030404E10Rik	RIKEN cDNA 9030404E10 gene	11563	0.15
chr9_96727521_96727672	0.43	Zbtb38	zinc finger and BTB domain containing 38	1440	0.37
chr6_22351338_22351531	0.43	Fam3c	family with sequence similarity 3, member C	4639	0.3
chr10_24832460_24832775	0.42	Enpp3	ectonucleotide pyrophosphatase/phosphodiesterase 3	811	0.63
chr17_10315275_10315426	0.42	Qk	quaking	4011	0.27
chr10_128069634_128069785	0.42	Ptges3	prostaglandin E synthase 3	437	0.63
chr3_51159032_51159226	0.42	Gm38246	predicted gene, 38246	55469	0.09
chr1_91465224_91465404	0.42	Gm28381	predicted gene 28381	4784	0.12
chr19_17599285_17599457	0.42	Gm17819	predicted gene, 17819	93392	0.08
chr12_70011836_70012241	0.42	Nin	ninein	14789	0.11
chr12_16535033_16535184	0.42	Lpin1	lipin 1	26930	0.22
chr19_60569243_60569459	0.41	Gm25238	predicted gene, 25238	11178	0.18
chr4_123425945_123426170	0.41	Gm12924	predicted gene 12924	9560	0.17
chr10_45070700_45070964	0.41	Prep	prolyl endopeptidase	3629	0.22
chr12_117728238_117728544	0.41	Gm18955	predicted gene, 18955	4419	0.24
chr2_114384654_114385010	0.41	Gm29234	predicted gene 29234	111397	0.06
chr11_120804691_120805015	0.41	Fasn	fatty acid synthase	3752	0.1
chr11_4048460_4048709	0.41	Sec14l4	SEC14-like lipid binding 4	6847	0.11
chr5_123033680_123033835	0.41	Gm43412	predicted gene 43412	2243	0.14
chr1_75217546_75217722	0.41	Tuba4a	tubulin, alpha 4A	200	0.81
chr5_124194760_124194955	0.41	Pitpnm2os2	phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 2	50	0.96
chr7_101084310_101084461	0.40	Fchsd2	FCH and double SH3 domains 2	8478	0.17
chr15_60921264_60921780	0.40	A1bg	alpha-1-B glycoprotein	256	0.91
chr1_23237656_23237879	0.40	Gm29506	predicted gene 29506	2094	0.23
chr9_102836112_102836267	0.40	Ryk	receptor-like tyrosine kinase	1207	0.4
chr8_45341558_45341748	0.40	Cyp4v3	cytochrome P450, family 4, subfamily v, polypeptide 3	8437	0.15
chr9_14061834_14061992	0.40	1700019J19Rik	RIKEN cDNA 1700019J19 gene	27707	0.17
chr17_87672860_87673165	0.39	Msh2	mutS homolog 2	403	0.86
chr1_55092544_55092728	0.39	Hspe1	heat shock protein 1 (chaperonin 10)	4322	0.12
chr8_44962712_44962905	0.39	Fat1	FAT atypical cadherin 1	12594	0.2
chr7_45487703_45488224	0.39	Dhdh	dihydrodiol dehydrogenase (dimeric)	561	0.38
chr16_23967660_23967916	0.39	Bcl6	B cell leukemia/lymphoma 6	4592	0.19
chr7_129592251_129592602	0.39	Wdr11	WD repeat domain 11	508	0.85
chr16_42968234_42968386	0.39	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	12679	0.22
chr13_24325258_24325614	0.39	Cmah	cytidine monophospho-N-acetylneuraminic acid hydroxylase	1968	0.19
chr16_6776618_6776797	0.39	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	32515	0.26
chr13_9493955_9494714	0.39	Gm48871	predicted gene, 48871	48434	0.12
chr3_102384557_102384708	0.39	Gm43245	predicted gene 43245	5375	0.21
chr15_85761461_85761612	0.39	Ppara	peroxisome proliferator activated receptor alpha	10678	0.15
chr13_9058526_9058733	0.39	Gm36264	predicted gene, 36264	17822	0.13
chr2_130841256_130841407	0.38	4930402H24Rik	RIKEN cDNA 4930402H24 gene	1186	0.43
chr4_92376164_92376339	0.38	Gm12638	predicted gene 12638	2903	0.4
chr2_51038958_51039119	0.38	Rnd3	Rho family GTPase 3	110056	0.06
chr11_84866076_84866227	0.38	Ggnbp2	gametogenetin binding protein 2	4051	0.13
chr1_187215201_187215623	0.38	Spata17	spermatogenesis associated 17	9	0.58
chr9_106236583_106237078	0.38	Alas1	aminolevulinic acid synthase 1	254	0.85
chr19_14596702_14596877	0.38	Tle4	transducin-like enhancer of split 4	1250	0.59
chr6_87850155_87850511	0.38	Cnbp	cellular nucleic acid binding protein	689	0.36
chr3_108571833_108572174	0.38	Taf13	TATA-box binding protein associated factor 13	292	0.78
chr2_67898259_67898744	0.38	Gm37964	predicted gene, 37964	95	0.98
chr3_62458537_62458746	0.38	Dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36	13946	0.24
chr13_36731949_36732177	0.38	Nrn1	neuritin 1	317	0.87
chr2_160797467_160797706	0.38	Plcg1	phospholipase C, gamma 1	37468	0.11
chr3_149437041_149437628	0.37	Gm30382	predicted gene, 30382	7942	0.29
chr2_134708873_134709037	0.37	Gm14037	predicted gene 14037	22152	0.2
chr7_132950275_132950525	0.37	Zranb1	zinc finger, RAN-binding domain containing 1	816	0.56
chr14_40032830_40033131	0.37	Gm25012	predicted gene, 25012	23078	0.21
chr6_139587785_139588001	0.37	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	656	0.72
chr14_121779984_121780147	0.37	Dock9	dedicator of cytokinesis 9	17772	0.2
chr5_9114274_9114428	0.37	Tmem243	transmembrane protein 243, mitochondrial	1103	0.47
chr6_17542198_17542379	0.37	Met	met proto-oncogene	4685	0.27
chr14_20930671_20931107	0.37	Vcl	vinculin	1491	0.44
chr16_24933416_24933784	0.37	Gm22672	predicted gene, 22672	49427	0.16
chr4_133816308_133816669	0.37	Gm12974	predicted gene 12974	68	0.96
chr6_139577371_139577524	0.36	4930443G03Rik	RIKEN cDNA 4930443G03 gene	242	0.93
chr2_77508562_77509023	0.36	Zfp385b	zinc finger protein 385B	10743	0.25
chr6_17747909_17748076	0.36	Gm42852	predicted gene 42852	908	0.41
chr1_108024783_108024954	0.36	Gm28282	predicted gene 28282	61561	0.12
chr1_39433880_39434250	0.36	Gm37265	predicted gene, 37265	14133	0.16
chr6_115646455_115646777	0.36	Gm14335	predicted gene 14335	7557	0.12
chr4_101245751_101246055	0.35	Jak1	Janus kinase 1	19320	0.12
chr5_108065271_108065446	0.35	Mtf2	metal response element binding transcription factor 2	316	0.86
chr8_119699356_119699536	0.35	Atp2c2	ATPase, Ca++ transporting, type 2C, member 2	563	0.67
chr4_150393280_150393601	0.35	Rere	arginine glutamic acid dipeptide (RE) repeats	12954	0.22
chr9_70930366_70930582	0.35	Gm32017	predicted gene, 32017	14	0.98
chr3_46391803_46391994	0.35	Gm18843	predicted gene, 18843	21504	0.24
chr13_46735806_46736396	0.35	Nup153	nucleoporin 153	8161	0.17
chr9_122126128_122126308	0.35	4632418H02Rik	RIKEN cDNA 4632418H02 gene	1076	0.38
chr1_155896484_155896645	0.35	Cep350	centrosomal protein 350	1967	0.24
chr4_141859104_141859255	0.35	Ctrc	chymotrypsin C (caldecrin)	12820	0.1
chr1_153740478_153741329	0.35	Rgs16	regulator of G-protein signaling 16	554	0.59
chr2_18103156_18103497	0.35	Mllt10	myeloid/lymphoid or mixed-lineage leukemia; translocated to, 10	20383	0.12
chr10_128097775_128098188	0.34	Baz2a	bromodomain adjacent to zinc finger domain, 2A	1601	0.18
chr16_17550267_17550511	0.34	Lrrc74b	leucine rich repeat containing 74B	4043	0.11
chr8_26088168_26088328	0.34	Hook3	hook microtubule tethering protein 3	4034	0.13
chr19_36453244_36453431	0.34	F530104D19Rik	RIKEN cDNA F530104D19 gene	2180	0.28
chr6_134243786_134243942	0.34	Gm17089	predicted gene 17089	153	0.94
chr9_63590587_63590762	0.34	Iqch	IQ motif containing H	11743	0.18
chr5_23562685_23562882	0.34	Srpk2	serine/arginine-rich protein specific kinase 2	13413	0.19
chr17_34857042_34857488	0.34	Mir6972	microRNA 6972	367	0.53
chr2_31499430_31499808	0.34	Ass1	argininosuccinate synthetase 1	1107	0.5
chr3_98763242_98763403	0.34	Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	195	0.92
chr4_123665270_123665565	0.34	Gm12925	predicted gene 12925	464	0.55
chr11_100485778_100486208	0.34	Acly	ATP citrate lyase	6482	0.09
chr7_132959402_132959558	0.34	Zranb1	zinc finger, RAN-binding domain containing 1	9896	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Otx1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.2	0.5	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.6	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.5	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1	0.4	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.3	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.1	0.3	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.1	0.3	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.1	0.3	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.1	0.4	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.3	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.1	0.2	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.4	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.2	GO:0071725	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1	0.4	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.3	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.2	GO:0006203	dGTP catabolic process(GO:0006203)
0.1	0.2	GO:0006553	lysine metabolic process(GO:0006553)
0.1	0.2	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.2	GO:0016237	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.1	0.3	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1	0.2	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1	0.2	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.2	GO:0036022	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.1	0.4	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	0.2	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.2	GO:0042732	D-xylose metabolic process(GO:0042732)
0.1	0.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.2	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.2	GO:0030091	protein repair(GO:0030091)
0.1	0.3	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1	0.2	GO:0061511	centriole elongation(GO:0061511)
0.0	0.2	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.4	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0000432	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0	0.1	GO:0060584	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.2	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0	0.2	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.2	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.1	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.2	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:0035022	positive regulation of Rac protein signal transduction(GO:0035022)
0.0	0.2	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.4	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.3	GO:0090161	Golgi ribbon formation(GO:0090161)
0.0	0.1	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:1902065	response to L-glutamate(GO:1902065)
0.0	0.7	GO:0007020	microtubule nucleation(GO:0007020)
0.0	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.0	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.0	0.1	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.3	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.1	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.2	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.1	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0	0.3	GO:2000671	regulation of motor neuron apoptotic process(GO:2000671)
0.0	0.4	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.2	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.2	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.3	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0019747	regulation of isoprenoid metabolic process(GO:0019747)
0.0	0.2	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.1	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0000189	MAPK import into nucleus(GO:0000189)
0.0	0.2	GO:0045916	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.2	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.0	GO:0002371	dendritic cell cytokine production(GO:0002371) regulation of dendritic cell cytokine production(GO:0002730)
0.0	0.1	GO:0035793	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.1	GO:1902894	negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0	0.1	GO:0070295	renal water absorption(GO:0070295)
0.0	0.2	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.3	GO:0006103	2-oxoglutarate metabolic process(GO:0006103)
0.0	0.1	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.3	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.4	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.0	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.0	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.1	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.0	GO:0002085	inhibition of neuroepithelial cell differentiation(GO:0002085)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.1	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.0	0.2	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.1	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.0	0.0	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
0.0	0.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.1	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.0	0.2	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	1.2	GO:0006892	post-Golgi vesicle-mediated transport(GO:0006892)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.2	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:1900165	negative regulation of interleukin-6 secretion(GO:1900165)
0.0	0.1	GO:0006678	glucosylceramide metabolic process(GO:0006678)
0.0	0.1	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.2	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.2	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.1	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.2	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.1	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.0	0.0	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.0	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0039533	regulation of MDA-5 signaling pathway(GO:0039533)
0.0	0.1	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.2	GO:0035873	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.1	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:0003284	septum primum development(GO:0003284)
0.0	0.3	GO:0072661	protein targeting to plasma membrane(GO:0072661)
0.0	0.0	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.0	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0046078	dUMP metabolic process(GO:0046078)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0032365	intracellular lipid transport(GO:0032365)
0.0	0.1	GO:0002002	regulation of angiotensin levels in blood(GO:0002002)
0.0	0.0	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.0	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.1	GO:0045542	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.1	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.0	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.1	GO:0097340	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.3	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.1	GO:0042347	negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0	0.0	GO:1903059	regulation of protein lipidation(GO:1903059) positive regulation of protein lipidation(GO:1903061)
0.0	0.0	GO:0060278	regulation of ovulation(GO:0060278)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.0	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.0	GO:0009642	response to light intensity(GO:0009642)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.2	GO:0061462	protein localization to lysosome(GO:0061462)
0.0	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.0	GO:0046208	spermine catabolic process(GO:0046208)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.0	GO:0031443	fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0030854	positive regulation of granulocyte differentiation(GO:0030854)
0.0	0.1	GO:0055119	relaxation of cardiac muscle(GO:0055119)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.0	GO:0090148	membrane fission(GO:0090148)
0.0	0.0	GO:0072592	oxygen metabolic process(GO:0072592)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.0	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.1	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.0	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0061157	mRNA destabilization(GO:0061157)
0.0	0.0	GO:0060965	negative regulation of gene silencing by miRNA(GO:0060965)
0.0	0.1	GO:1900037	regulation of cellular response to hypoxia(GO:1900037)
0.0	0.1	GO:0045792	negative regulation of cell size(GO:0045792)
0.0	0.1	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.1	GO:0006020	inositol metabolic process(GO:0006020)
0.0	0.1	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:1902254	negative regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902254)
0.0	0.0	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.0	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.2	GO:0031297	replication fork processing(GO:0031297)
0.0	0.0	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.0	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.0	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.0	GO:0021550	medulla oblongata development(GO:0021550)
0.0	0.1	GO:0043486	histone exchange(GO:0043486)
0.0	0.0	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.0	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.0	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.0	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.0	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.0	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.0	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.1	GO:0045947	negative regulation of translational initiation(GO:0045947)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.1	GO:0021932	hindbrain radial glia guided cell migration(GO:0021932)
0.0	0.0	GO:0036394	amylase secretion(GO:0036394)
0.0	0.0	GO:2001182	regulation of interleukin-12 secretion(GO:2001182)
0.0	0.2	GO:0006783	heme biosynthetic process(GO:0006783)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.5	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.1	1.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.1	0.6	GO:0016342	catenin complex(GO:0016342)
0.1	0.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.2	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.2	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.3	GO:0005869	dynactin complex(GO:0005869)
0.0	0.6	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.0	0.6	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.4	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.2	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0051286	cell tip(GO:0051286)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0036449	microtubule minus-end(GO:0036449)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.0	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.3	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.6	GO:0045335	phagocytic vesicle(GO:0045335)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.0	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0000176	nuclear exosome (RNase complex)(GO:0000176)
0.0	0.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.0	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0008142	oxysterol binding(GO:0008142)
0.1	1.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.3	GO:0032142	single guanine insertion binding(GO:0032142)
0.1	0.4	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.4	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.4	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.2	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.1	0.6	GO:0045294	alpha-catenin binding(GO:0045294)
0.1	0.2	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.2	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.1	0.3	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1	0.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.3	GO:0035256	G-protein coupled glutamate receptor binding(GO:0035256)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.3	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.3	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.3	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.2	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.1	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0019002	GMP binding(GO:0019002)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.2	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.0	GO:0034211	GTP-dependent protein kinase activity(GO:0034211)
0.0	0.3	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.6	GO:0004119	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.2	GO:0052849	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.4	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	0.3	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0030519	snoRNP binding(GO:0030519)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.3	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.3	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.3	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.3	GO:0016864	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.2	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.3	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.0	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.3	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.2	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0005527	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.0	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.0	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.0	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0	0.2	GO:0016860	intramolecular oxidoreductase activity(GO:0016860)
0.0	0.1	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.0	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.0	GO:0004677	DNA-dependent protein kinase activity(GO:0004677)
0.0	0.5	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.3	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.1	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.0	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.1	GO:0001163	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.0	GO:0047756	chondroitin 4-sulfotransferase activity(GO:0047756)
0.0	0.0	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.2	GO:0030515	snoRNA binding(GO:0030515)
0.0	0.1	GO:0031005	filamin binding(GO:0031005)
0.0	0.2	GO:0016755	transferase activity, transferring amino-acyl groups(GO:0016755)
0.0	0.2	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0015271	outward rectifier potassium channel activity(GO:0015271)
0.0	0.1	GO:0070742	C2H2 zinc finger domain binding(GO:0070742)
0.0	0.0	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0015254	glycerol transmembrane transporter activity(GO:0015168) glycerol channel activity(GO:0015254)
0.0	0.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.0	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.0	GO:0071253	connexin binding(GO:0071253)
0.0	0.2	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.2	GO:0080025	phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.2	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.4	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.2	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.7	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.2	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.4	ST G ALPHA I PATHWAY	G alpha i Pathway
0.6	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.2	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	PID NETRIN PATHWAY	Netrin-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.5	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.7	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.3	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.4	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.2	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.5	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.3	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.3	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.3	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.2	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.1	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.1	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.2	REACTOME VIRAL MESSENGER RNA SYNTHESIS	Genes involved in Viral Messenger RNA Synthesis
0.3	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.1	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.5	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.7	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.2	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.1	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification
0.4	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.3	REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT	Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.1	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors

Results for Otx1

Z-value: 1.85

Motif logo

Transcription factors associated with Otx1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Otx1 motif across conditions

Conditions sorted by the z-value of the Otx1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Otx1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: