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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Ovol1

Z-value: 1.98

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Transcription factors associated with Ovol1

Gene Symbol	Gene ID	Gene Info
Ovol1 Ensembl NCBI MGI UniProt	ENSMUSG00000024922.1	ovo like zinc finger 1

Activity of the Ovol1 motif across conditions

Conditions sorted by the z-value of the Ovol1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_186325767_186325937	2.30	Gm37491	predicted gene, 37491	21463	0.24
chr14_114864274_114864425	1.68	Gm49010	predicted gene, 49010	12161	0.18
chr16_43348317_43348468	1.54	Zbtb20	zinc finger and BTB domain containing 20	14656	0.16
chr8_105095287_105095438	1.43	Ces3b	carboxylesterase 3B	6743	0.11
chr9_74331100_74331251	1.35	Gm24141	predicted gene, 24141	31435	0.18
chr9_85551927_85552078	1.18	Gm48834	predicted gene, 48834	1763	0.42
chr10_99656891_99657084	1.13	Gm35101	predicted gene, 35101	12527	0.16
chr10_113290132_113290294	1.10	Gm47532	predicted gene, 47532	133971	0.05
chr12_8081681_8081832	1.04	Apob	apolipoprotein B	69397	0.1
chr11_51753632_51753825	0.99	Sec24a	Sec24 related gene family, member A (S. cerevisiae)	2483	0.22
chr1_64920991_64921142	0.95	Plekhm3	pleckstrin homology domain containing, family M, member 3	7031	0.17
chr14_51255648_51255799	0.93	Rnase2a	ribonuclease, RNase A family, 2A (liver, eosinophil-derived neurotoxin)	389	0.76
chr1_21245441_21245592	0.93	Gsta3	glutathione S-transferase, alpha 3	4887	0.13
chr9_74881714_74881880	0.92	Onecut1	one cut domain, family member 1	15313	0.15
chr16_43287089_43287284	0.90	Gm37946	predicted gene, 37946	21095	0.17
chr14_62909739_62909890	0.87	n-R5s47	nuclear encoded rRNA 5S 47	40100	0.09
chr12_32707578_32707729	0.87	Gm18726	predicted gene, 18726	2508	0.33
chr8_93183570_93183871	0.84	Gm45909	predicted gene 45909	7638	0.14
chr18_65989569_65989860	0.83	Lman1	lectin, mannose-binding, 1	3946	0.15
chr5_89352355_89352713	0.80	Gc	vitamin D binding protein	83094	0.1
chr17_84650132_84650304	0.78	Dync2li1	dynein cytoplasmic 2 light intermediate chain 1	943	0.47
chr3_62404931_62405082	0.77	Arhgef26	Rho guanine nucleotide exchange factor (GEF) 26	14662	0.25
chr2_172975275_172975541	0.72	Spo11	SPO11 meiotic protein covalently bound to DSB	2292	0.24
chr9_74892937_74893252	0.72	Onecut1	one cut domain, family member 1	26610	0.14
chr15_6891349_6891647	0.71	Osmr	oncostatin M receptor	16529	0.26
chr12_40574426_40574700	0.71	Dock4	dedicator of cytokinesis 4	128227	0.05
chr4_109785016_109785167	0.70	Gm12808	predicted gene 12808	30274	0.18
chr16_45970303_45970469	0.69	Phldb2	pleckstrin homology like domain, family B, member 2	16788	0.15
chr7_80174092_80174243	0.69	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	12674	0.1
chr15_7199123_7199469	0.68	Egflam	EGF-like, fibronectin type III and laminin G domains	23773	0.22
chr5_62037819_62037970	0.68	Gm42430	predicted gene 42430	33674	0.23
chr1_67227779_67227978	0.68	Gm15668	predicted gene 15668	21322	0.2
chr11_16818044_16818409	0.67	Egfros	epidermal growth factor receptor, opposite strand	12476	0.22
chr2_146974639_146974805	0.66	Kiz	kizuna centrosomal protein	21839	0.2
chr10_117435719_117435921	0.66	Gm9002	predicted gene 9002	6202	0.15
chr5_123020545_123020720	0.63	Orai1	ORAI calcium release-activated calcium modulator 1	5294	0.09
chr18_7657709_7657860	0.62	Mpp7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	30918	0.17
chr17_28982482_28982633	0.61	Stk38	serine/threonine kinase 38	371	0.72
chr3_27360140_27360291	0.60	Ghsr	growth hormone secretagogue receptor	11136	0.21
chr13_62909790_62909949	0.59	Fbp1	fructose bisphosphatase 1	21587	0.13
chr7_93588215_93588366	0.59	Gm45039	predicted gene 45039	20026	0.19
chr9_57711329_57711506	0.59	Edc3	enhancer of mRNA decapping 3	2850	0.18
chr2_121428399_121428550	0.59	Pdia3	protein disulfide isomerase associated 3	3844	0.09
chr11_16836119_16836554	0.59	Egfros	epidermal growth factor receptor, opposite strand	5634	0.23
chr14_25577605_25577757	0.57	Zmiz1	zinc finger, MIZ-type containing 1	29676	0.15
chr11_16818941_16819203	0.57	Egfros	epidermal growth factor receptor, opposite strand	11630	0.22
chr8_3048117_3048282	0.57	Gm44634	predicted gene 44634	8095	0.2
chr16_37902046_37902197	0.57	Gpr156	G protein-coupled receptor 156	14375	0.14
chr3_129535291_129535442	0.57	Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	2639	0.2
chr10_121796142_121796293	0.56	Srgap1	SLIT-ROBO Rho GTPase activating protein 1	10887	0.19
chr3_60141611_60141822	0.54	Gm24382	predicted gene, 24382	13969	0.22
chr8_126932350_126932537	0.54	Gm26397	predicted gene, 26397	12537	0.14
chr16_87713148_87713314	0.53	Bach1	BTB and CNC homology 1, basic leucine zipper transcription factor 1	14227	0.2
chr7_107574446_107574681	0.53	Olfml1	olfactomedin-like 1	6797	0.16
chr6_54033623_54033822	0.52	Chn2	chimerin 2	5832	0.22
chr14_34328663_34328894	0.51	Glud1	glutamate dehydrogenase 1	116	0.93
chr10_40512569_40512723	0.50	Gm18671	predicted gene, 18671	36246	0.14
chr2_154868249_154868417	0.50	Eif2s2	eukaryotic translation initiation factor 2, subunit 2 (beta)	24449	0.17
chr13_44291297_44291488	0.50	Gm29676	predicted gene, 29676	10943	0.21
chr15_3107457_3107608	0.50	Gm49222	predicted gene, 49222	8077	0.21
chr5_90474479_90475042	0.50	Alb	albumin	12060	0.14
chr8_80263585_80263752	0.50	Gm45430	predicted gene 45430	68469	0.12
chr4_3319048_3319257	0.49	Gm11786	predicted gene 11786	8023	0.21
chr13_52191366_52191526	0.48	Gm48199	predicted gene, 48199	11035	0.27
chr15_99038783_99039270	0.48	Tuba1c	tubulin, alpha 1C	8705	0.09
chr4_135649660_135649811	0.48	1700029M20Rik	RIKEN cDNA 1700029M20 gene	22482	0.13
chr12_51274262_51274425	0.47	Rps11-ps4	ribosomal protein S11, pseudogene 4	23144	0.22
chr18_34937071_34937222	0.47	Hspa9	heat shock protein 9	2164	0.19
chr7_97411671_97412103	0.47	Thrsp	thyroid hormone responsive	5632	0.13
chr10_88784083_88784275	0.47	Utp20	UTP20 small subunit processome component	1513	0.36
chr1_67213400_67213609	0.46	Gm15668	predicted gene 15668	35696	0.17
chr9_106230886_106231037	0.46	Alas1	aminolevulinic acid synthase 1	6123	0.1
chr3_51254730_51254881	0.46	Elf2	E74-like factor 2	5436	0.14
chr15_59447953_59448104	0.45	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	73741	0.09
chr6_121171179_121171645	0.44	Pex26	peroxisomal biogenesis factor 26	12255	0.13
chr2_81270139_81270299	0.44	Gm23900	predicted gene, 23900	273123	0.01
chr19_12717960_12718111	0.44	Gm15962	predicted gene 15962	3168	0.14
chr6_54465003_54465192	0.44	Wipf3	WAS/WASL interacting protein family, member 3	6905	0.17
chr1_48564270_48564440	0.44	Gm28830	predicted gene 28830	36716	0.21
chr17_12453269_12453430	0.44	C030013G03Rik	RIKEN cDNA C030013G03 gene	13495	0.19
chr3_69656373_69656571	0.44	Gm37380	predicted gene, 37380	5294	0.19
chr3_95864904_95865315	0.43	Mrps21	mitochondrial ribosomal protein S21	1802	0.16
chr8_36753814_36753974	0.43	Dlc1	deleted in liver cancer 1	20840	0.26
chr11_120815765_120815980	0.43	Fasn	fatty acid synthase	417	0.69
chr11_22846775_22846926	0.43	Gm23772	predicted gene, 23772	18	0.96
chr9_19690640_19690851	0.43	Gm7769	predicted gene 7769	126	0.94
chr4_117997840_117998088	0.43	9530034E10Rik	RIKEN cDNA 9530034E10 gene	22928	0.14
chr15_81481395_81481613	0.43	Gm49406	predicted gene, 49406	4877	0.14
chr5_113127021_113127172	0.43	F830115B05Rik	RIKEN cDNA F830115B05 gene	7632	0.11
chr6_52606460_52606970	0.43	Gm44434	predicted gene, 44434	3470	0.19
chr10_34131764_34131915	0.42	Calhm6	calcium homeostasis modulator family member 6	3855	0.16
chr6_119359922_119360073	0.42	Cacna2d4	calcium channel, voltage-dependent, alpha 2/delta subunit 4	27435	0.15
chr11_16756467_16757088	0.42	Egfr	epidermal growth factor receptor	4547	0.23
chr15_55043149_55043337	0.41	Taf2	TATA-box binding protein associated factor 2	2923	0.22
chr2_34779244_34779475	0.41	Hspa5	heat shock protein 5	4512	0.15
chr1_63112731_63113827	0.41	Ino80dos	INO80 complex subunit D, opposite strand	201	0.84
chr1_59687623_59687774	0.41	Nop58	NOP58 ribonucleoprotein	2481	0.14
chr5_4076458_4076777	0.41	Gm43031	predicted gene 43031	3046	0.24
chr5_23562685_23562882	0.41	Srpk2	serine/arginine-rich protein specific kinase 2	13413	0.19
chr9_21838672_21838867	0.41	Angptl8	angiopoietin-like 8	3259	0.14
chr13_112118684_112118873	0.41	Gm31104	predicted gene, 31104	19338	0.19
chr10_31501811_31501962	0.41	Gm47687	predicted gene, 47687	49804	0.09
chr14_76409148_76409302	0.41	Tsc22d1	TSC22 domain family, member 1	5736	0.29
chr19_44393983_44394181	0.41	Scd1	stearoyl-Coenzyme A desaturase 1	12608	0.14
chr15_7162840_7163002	0.40	Lifr	LIF receptor alpha	8568	0.27
chr2_20921163_20921333	0.40	Arhgap21	Rho GTPase activating protein 21	6554	0.21
chr3_46391803_46391994	0.40	Gm18843	predicted gene, 18843	21504	0.24
chr3_52648763_52649088	0.40	Gm10293	predicted pseudogene 10293	36090	0.17
chr3_31408324_31408475	0.39	Gm38025	predicted gene, 38025	67387	0.12
chr16_42998828_42999221	0.39	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	43393	0.16
chr12_54362251_54362402	0.39	Gm7550	predicted gene 7550	28992	0.13
chr15_58980885_58981061	0.39	4930544F09Rik	RIKEN cDNA 4930544F09 gene	3163	0.21
chr12_30372879_30373073	0.39	Sntg2	syntrophin, gamma 2	289	0.93
chr11_16817302_16817617	0.38	Egfros	epidermal growth factor receptor, opposite strand	13243	0.21
chr13_56571965_56572403	0.38	2010203P06Rik	RIKEN cDNA 2010203P06 gene	23353	0.14
chr18_12744753_12744936	0.38	Gm7599	predicted gene 7599	1585	0.28
chr8_77046087_77046238	0.38	Nr3c2	nuclear receptor subfamily 3, group C, member 2	81851	0.09
chr14_116350280_116350464	0.37	Gm38045	predicted gene, 38045	399843	0.01
chr2_79919674_79919842	0.37	Pde1a	phosphodiesterase 1A, calmodulin-dependent	8033	0.3
chr2_4941693_4941844	0.37	Gm13194	predicted gene 13194	406	0.76
chr6_28779093_28779393	0.37	Snd1	staphylococcal nuclease and tudor domain containing 1	2695	0.29
chr7_128623495_128623646	0.37	Inpp5f	inositol polyphosphate-5-phosphatase F	12210	0.12
chr10_24396476_24396638	0.37	Gm15271	predicted gene 15271	50933	0.14
chr10_30825158_30825321	0.37	Hey2	hairy/enhancer-of-split related with YRPW motif 2	16776	0.15
chr7_67649875_67650106	0.37	Ttc23	tetratricopeptide repeat domain 23	840	0.51
chr12_79453000_79453184	0.36	Rad51b	RAD51 paralog B	125739	0.05
chr6_24609749_24609900	0.36	Lmod2	leiomodin 2 (cardiac)	12062	0.14
chr9_32718921_32719093	0.36	Gm27240	predicted gene 27240	7836	0.2
chr2_160361611_160362000	0.36	Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	5260	0.27
chr13_86111453_86111688	0.36	Cox7c	cytochrome c oxidase subunit 7C	64666	0.12
chr17_28241245_28241399	0.36	Ppard	peroxisome proliferator activator receptor delta	8515	0.11
chr19_46624218_46624386	0.36	Wbp1l	WW domain binding protein 1 like	901	0.49
chr15_64195944_64196287	0.35	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	12376	0.24
chr5_53202803_53202991	0.35	Sel1l3	sel-1 suppressor of lin-12-like 3 (C. elegans)	10418	0.2
chr3_9521650_9521991	0.35	Gm38001	predicted gene, 38001	25652	0.2
chr4_121189641_121189792	0.35	Rlf	rearranged L-myc fusion sequence	1182	0.42
chr3_144446211_144446394	0.35	Gm5857	predicted gene 5857	18630	0.18
chr19_31968064_31968231	0.34	9130016M20Rik	RIKEN cDNA 9130016M20 gene	18063	0.21
chr19_47646596_47646802	0.34	Col17a1	collagen, type XVII, alpha 1	2896	0.17
chr15_38570240_38570408	0.34	Gm29697	predicted gene, 29697	3672	0.15
chr2_84995821_84996178	0.34	Prg3	proteoglycan 3	7784	0.12
chr1_59371411_59371704	0.34	Gm29016	predicted gene 29016	7373	0.21
chr6_129216337_129216553	0.33	2310001H17Rik	RIKEN cDNA 2310001H17 gene	17529	0.1
chr3_152762447_152762598	0.33	Pigk	phosphatidylinositol glycan anchor biosynthesis, class K	859	0.63
chr14_121072919_121073071	0.32	Farp1	FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)	29084	0.23
chr15_81253437_81253614	0.32	8430426J06Rik	RIKEN cDNA 8430426J06 gene	1663	0.31
chr14_69626550_69626701	0.32	Gm37513	predicted gene, 37513	10579	0.11
chr16_18073808_18074007	0.32	Dgcr6	DiGeorge syndrome critical region gene 6	4427	0.15
chr15_35876385_35876551	0.32	Vps13b	vacuolar protein sorting 13B	4746	0.19
chr12_104025874_104026200	0.32	Gm37496	predicted gene, 37496	1610	0.23
chr14_18232288_18232439	0.32	Nr1d2	nuclear receptor subfamily 1, group D, member 2	6648	0.15
chr19_57258075_57258251	0.32	4930449E18Rik	RIKEN cDNA 4930449E18 gene	15797	0.18
chr15_7198099_7198411	0.31	Egflam	EGF-like, fibronectin type III and laminin G domains	24814	0.22
chr9_30936768_30936954	0.31	Adamts8	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 8	5701	0.21
chr7_120184451_120184607	0.31	Anks4b	ankyrin repeat and sterile alpha motif domain containing 4B	10671	0.13
chr2_134931319_134931796	0.31	Gm14036	predicted gene 14036	127608	0.05
chr11_16782319_16782716	0.31	Egfr	epidermal growth factor receptor	30287	0.16
chr18_3276237_3276415	0.31	Crem	cAMP responsive element modulator	4752	0.25
chr8_56292003_56292154	0.31	Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	2507	0.34
chr2_31487515_31488471	0.31	Ass1	argininosuccinate synthetase 1	9779	0.18
chr1_193926856_193927030	0.31	Gm21362	predicted gene, 21362	59934	0.16
chr17_24868993_24869535	0.30	Igfals	insulin-like growth factor binding protein, acid labile subunit	3267	0.1
chr19_45843362_45843693	0.30	Gm50196	predicted gene, 50196	90	0.96
chr12_69695612_69695763	0.30	Sos2	SOS Ras/Rho guanine nucleotide exchange factor 2	13835	0.14
chr3_81149765_81149938	0.30	Gm16000	predicted gene 16000	109414	0.06
chr5_96437978_96438159	0.30	Gm33050	predicted gene, 33050	19675	0.21
chr9_98434324_98434475	0.30	Rbp1	retinol binding protein 1, cellular	11438	0.2
chr3_130694798_130695032	0.30	Ostc	oligosaccharyltransferase complex subunit (non-catalytic)	1707	0.27
chr1_74807738_74808135	0.30	Wnt10a	wingless-type MMTV integration site family, member 10A	14573	0.11
chr8_46477705_46478047	0.30	Gm45244	predicted gene 45244	4286	0.17
chr1_140267910_140268090	0.30	Gm37777	predicted gene, 37777	1513	0.46
chr10_91261198_91261441	0.30	Gm18705	predicted gene, 18705	1975	0.31
chr2_17192790_17192972	0.30	Gm13322	predicted gene 13322	7394	0.26
chr8_93107061_93107411	0.30	Ces1c	carboxylesterase 1C	17293	0.14
chr7_39841504_39841670	0.30	4930558N11Rik	RIKEN cDNA 4930558N11 gene	43845	0.11
chr3_127009818_127009969	0.30	Gm43750	predicted gene 43750	908	0.45
chr16_42962415_42962640	0.30	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	6896	0.24
chr5_145793363_145793514	0.29	Cyp3a44	cytochrome P450, family 3, subfamily a, polypeptide 44	12436	0.15
chr12_38115305_38115462	0.29	Gm35755	predicted gene, 35755	25481	0.21
chr18_79022725_79022904	0.29	Setbp1	SET binding protein 1	86577	0.1
chr11_75173089_75173918	0.29	Mir212	microRNA 212	115	0.56
chr14_19823120_19823271	0.29	Rtraf	RNA transcription, translation and transport factor	140	0.95
chr11_16809967_16810165	0.29	Egfros	epidermal growth factor receptor, opposite strand	20636	0.2
chr6_121221807_121221966	0.29	Gm15856	predicted gene 15856	4267	0.14
chr4_106767670_106767831	0.29	Acot11	acyl-CoA thioesterase 11	3806	0.18
chr15_7135727_7135925	0.29	Lifr	LIF receptor alpha	4716	0.31
chr7_98352590_98353259	0.29	Tsku	tsukushi, small leucine rich proteoglycan	7155	0.18
chr15_54578033_54578470	0.29	Mal2	mal, T cell differentiation protein 2	7059	0.27
chr2_105233444_105233738	0.29	Them7	thioesterase superfamily member 7	9249	0.24
chr19_32809166_32809317	0.28	Pten	phosphatase and tensin homolog	1984	0.43
chr8_18621633_18621799	0.28	Mcph1	microcephaly, primary autosomal recessive 1	3847	0.2
chr17_26885855_26886147	0.28	Gm17382	predicted gene, 17382	174	0.88
chr8_28267111_28267301	0.28	Gm8100	predicted gene 8100	81366	0.1
chr13_74023512_74023688	0.28	Gm6263	predicted gene 6263	3466	0.15
chr14_61695272_61695482	0.28	Gm37820	predicted gene, 37820	11867	0.11
chr4_101436475_101436672	0.28	Ak4	adenylate kinase 4	10650	0.16
chr6_53603997_53604187	0.28	Creb5	cAMP responsive element binding protein 5	30716	0.2
chr5_67299892_67300051	0.28	Slc30a9	solute carrier family 30 (zinc transporter), member 9	6984	0.18
chr9_44096490_44096809	0.28	Usp2	ubiquitin specific peptidase 2	3975	0.08
chr9_64251105_64251328	0.28	Map2k1	mitogen-activated protein kinase kinase 1	2415	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ovol1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.5	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.3	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.1	0.3	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.4	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.3	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.3	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	0.2	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.1	0.2	GO:0061144	alveolar secondary septum development(GO:0061144)
0.1	0.3	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.2	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.1	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.2	GO:0003096	renal sodium ion transport(GO:0003096)
0.1	0.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.2	GO:0045914	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.3	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.2	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.3	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.2	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.2	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.1	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.3	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.2	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.3	GO:0045713	low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.2	GO:0000237	leptotene(GO:0000237)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.7	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.2	GO:0042996	regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.3	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.3	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.1	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.1	GO:0015074	DNA integration(GO:0015074)
0.0	0.1	GO:0046533	negative regulation of photoreceptor cell differentiation(GO:0046533)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.1	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.0	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.0	0.1	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.1	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0048370	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.1	GO:0035437	maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0006370	7-methylguanosine mRNA capping(GO:0006370)
0.0	0.2	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.2	GO:0061418	regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061418)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.1	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.2	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.1	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.0	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:1902996	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.1	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.1	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.0	0.1	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.0	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.1	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.2	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0	0.0	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.0	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0031442	positive regulation of mRNA 3'-end processing(GO:0031442)
0.0	0.0	GO:0072050	S-shaped body morphogenesis(GO:0072050)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:2000739	regulation of mesenchymal stem cell differentiation(GO:2000739)
0.0	0.0	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.0	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:1903899	positive regulation of PERK-mediated unfolded protein response(GO:1903899)
0.0	0.1	GO:1902222	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.3	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.0	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.0	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.0	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.0	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
0.0	0.0	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.0	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.0	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.2	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.0	GO:0006562	proline catabolic process(GO:0006562)
0.0	0.1	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:1904751	regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751)
0.0	0.1	GO:0032495	response to muramyl dipeptide(GO:0032495)
0.0	0.0	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.0	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0006207	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.0	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0010459	negative regulation of heart rate(GO:0010459)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:0002176	male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0	0.1	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.0	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0000972	transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0	0.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.0	GO:0034755	iron ion transmembrane transport(GO:0034755)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0071305	cellular response to vitamin D(GO:0071305)
0.0	0.0	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.0	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.0	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.2	GO:0046852	positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.0	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.0	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.0	GO:0002175	protein localization to paranode region of axon(GO:0002175)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.0	0.1	GO:0042940	D-amino acid transport(GO:0042940)
0.0	0.1	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.0	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041)
0.0	0.0	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.0	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.0	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0070688	MLL5-L complex(GO:0070688)
0.1	0.2	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.2	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.2	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.2	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.4	GO:0031512	motile primary cilium(GO:0031512)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:0045254	pyruvate dehydrogenase complex(GO:0045254)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.2	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.2	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.1	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.1	GO:0000347	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.2	GO:0030686	90S preribosome(GO:0030686)
0.0	0.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.3	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0036128	CatSper complex(GO:0036128)
0.0	0.0	GO:0031094	platelet dense tubular network(GO:0031094)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.1	0.4	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.4	GO:0045504	dynein heavy chain binding(GO:0045504)
0.1	0.4	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.3	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.1	0.3	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.5	GO:0070728	leucine binding(GO:0070728)
0.1	0.3	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.3	GO:0032564	dATP binding(GO:0032564)
0.1	0.3	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.1	0.2	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.1	0.1	GO:0002134	UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551)
0.0	0.3	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.1	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.4	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0031698	beta-2 adrenergic receptor binding(GO:0031698)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.0	0.2	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0031781	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.4	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.2	GO:0019534	toxin transporter activity(GO:0019534)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.0	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.3	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0043910	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.5	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.1	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.0	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0017127	cholesterol transporter activity(GO:0017127)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0032558	adenyl deoxyribonucleotide binding(GO:0032558)
0.0	0.1	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.0	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.3	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.0	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.0	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.0	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.0	GO:0004645	phosphorylase activity(GO:0004645)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.4	GO:0034892	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.0	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.0	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.0	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.0	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.3	GO:0016645	oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.0	0.0	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.0	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.1	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0044466	2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.0	0.0	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.0	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0016918	retinal binding(GO:0016918)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.0	PID INSULIN PATHWAY	Insulin Pathway
0.0	0.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.0	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	0.0	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.0	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.0	0.7	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.5	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.3	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.2	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.0	REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS	Genes involved in Post NMDA receptor activation events
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.0	REACTOME APC C CDC20 MEDIATED DEGRADATION OF MITOTIC PROTEINS	Genes involved in APC/C:Cdc20 mediated degradation of mitotic proteins
0.0	0.6	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.2	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.4	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.1	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.2	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.1	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.1	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols

Results for Ovol1

Z-value: 1.98

Motif logo

Transcription factors associated with Ovol1

Activity of the Ovol1 motif across conditions

Conditions sorted by the z-value of the Ovol1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Ovol1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: