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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Pax1_Pax9

Z-value: 0.92

Motif logo

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Transcription factors associated with Pax1_Pax9

Gene Symbol Gene ID Gene Info
Pax1
ENSMUSG00000037034.9 paired box 1
Pax9
ENSMUSG00000001497.12 paired box 9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_147379046_147379216Pax1108490.163052-0.768.2e-02Click!
chr12_56695474_56695637Pax9840.9596010.721.0e-01Click!
chr12_56689847_56690002Pax918430.264032-0.374.7e-01Click!
chr12_56681655_56681817Pax9100310.1383470.216.9e-01Click!

Activity of the Pax1_Pax9 motif across conditions

Conditions sorted by the z-value of the Pax1_Pax9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr4_138510025_138510190 1.30 Camk2n1
 calcium/calmodulin-dependent protein kinase II inhibitor 1
 55793
 0.09
chr3_95652051_95652202 1.16 Mcl1
 myeloid cell leukemia sequence 1
 6662
 0.1
chr10_61160789_61160964 1.01 Tbata
 thymus, brain and testes associated
 11078
 0.15
chr11_94347313_94347820 0.89 Abcc3
 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
 3620
 0.18
chr2_158225371_158225751 0.77 D630003M21Rik
 RIKEN cDNA D630003M21 gene
 3661
 0.17
chr12_83375040_83375279 0.73 Dpf3
 D4, zinc and double PHD fingers, family 3
 24264
 0.22
chr9_43744780_43745133 0.70 Nectin1
 nectin cell adhesion molecule 1
 312
 0.63
chr6_128519043_128519655 0.67 Pzp
 PZP, alpha-2-macroglobulin like
 7354
 0.09
chr4_150544312_150544715 0.64 Gm13091
 predicted gene 13091
 24031
 0.18
chr5_120125413_120125579 0.62 Rbm19
 RNA binding motif protein 19
 6900
 0.2
chr2_25431594_25431764 0.61 Abca2
 ATP-binding cassette, sub-family A (ABC1), member 2
 2976
 0.1
chr2_90547180_90547349 0.60 Ptprj
 protein tyrosine phosphatase, receptor type, J
 33383
 0.16
chr12_3861728_3861888 0.56 Dnmt3aos
 DNA methyltransferase 3A, opposite strand
 436
 0.65
chr6_72637356_72637527 0.56 Gm37969
 predicted gene, 37969
 1114
 0.24
chr2_84386945_84387393 0.55 Calcrl
 calcitonin receptor-like
 11811
 0.2
chr9_120743578_120743729 0.55 Gm47064
 predicted gene, 47064
 7490
 0.13
chr8_94838256_94838419 0.54 Coq9
 coenzyme Q9
 16
 0.49
chr9_95573382_95573533 0.53 Paqr9
 progestin and adipoQ receptor family member IX
 13800
 0.12
chr19_24159844_24160184 0.52 Gm50308
 predicted gene, 50308
 5944
 0.18
chr10_78447521_78447672 0.51 Pdxk
 pyridoxal (pyridoxine, vitamin B6) kinase
 650
 0.43
chr5_22345406_22345583 0.48 Reln
 reelin
 792
 0.56
chr9_116947417_116947569 0.48 Gm18489
 predicted gene, 18489
 111665
 0.07
chr5_62622955_62623325 0.48 Gm43237
 predicted gene 43237
 9682
 0.2
chr2_33468229_33468380 0.47 Zbtb43
 zinc finger and BTB domain containing 43
 201
 0.93
chr6_92316933_92317084 0.46 Gm44024
 predicted gene, 44024
 35615
 0.15
chr4_140630998_140631188 0.46 Arhgef10l
 Rho guanine nucleotide exchange factor (GEF) 10-like
 14028
 0.17
chr15_78796259_78796421 0.46 Card10
 caspase recruitment domain family, member 10
 5825
 0.12
chr8_69822995_69823178 0.43 Lpar2
 lysophosphatidic acid receptor 2
 502
 0.65
chr12_75846819_75846970 0.41 Syne2
 spectrin repeat containing, nuclear envelope 2
 5836
 0.27
chr13_54562670_54563000 0.41 4833439L19Rik
 RIKEN cDNA 4833439L19 gene
 2456
 0.16
chr18_34328570_34328733 0.40 Srp19
 signal recognition particle 19
 2196
 0.29
chr17_80833916_80834067 0.40 C230072F16Rik
 RIKEN cDNA C230072F16 gene
 62802
 0.11
chr15_73511980_73512328 0.39 Dennd3
 DENN/MADD domain containing 3
 406
 0.84
chr11_94328339_94328510 0.38 Ankrd40
 ankyrin repeat domain 40
 170
 0.93
chr4_60154082_60154314 0.38 Mup2
 major urinary protein 2
 91
 0.94
chr17_87312523_87312681 0.37 Ttc7
 tetratricopeptide repeat domain 7
 3270
 0.19
chr4_106577621_106577846 0.37 Gm12744
 predicted gene 12744
 11375
 0.11
chr16_36711893_36712056 0.36 Ildr1
 immunoglobulin-like domain containing receptor 1
 3564
 0.17
chr6_141610892_141611057 0.36 Slco1b2
 solute carrier organic anion transporter family, member 1b2
 18544
 0.24
chr11_87442907_87443064 0.35 Rnu3b1
 U3B small nuclear RNA 1
 252
 0.8
chr6_35303511_35303677 0.35 Slc13a4
 solute carrier family 13 (sodium/sulfate symporters), member 4
 4535
 0.18
chr5_65421020_65421518 0.35 Ugdh
 UDP-glucose dehydrogenase
 1537
 0.22
chr4_135801615_135801933 0.35 Myom3
 myomesin family, member 3
 1130
 0.41
chr12_3858258_3858439 0.35 Dnmt3a
 DNA methyltransferase 3A
 2673
 0.24
chr8_120538771_120538958 0.34 Mir7687
 microRNA 7687
 168
 0.87
chr1_82281771_82282153 0.34 Irs1
 insulin receptor substrate 1
 9454
 0.19
chr10_28081351_28081686 0.34 Ptprk
 protein tyrosine phosphatase, receptor type, K
 6508
 0.24
chr6_90763367_90763528 0.34 Iqsec1
 IQ motif and Sec7 domain 1
 694
 0.67
chr1_59202432_59202591 0.32 Als2
 alsin Rho guanine nucleotide exchange factor
 16615
 0.14
chr12_17750620_17750832 0.32 Hpcal1
 hippocalcin-like 1
 22500
 0.2
chr16_4029500_4029663 0.32 Dnase1
 deoxyribonuclease I
 7361
 0.1
chr2_155546997_155547269 0.31 Gm20637
 predicted gene 20637
 748
 0.41
chr3_131327635_131327824 0.31 Sgms2
 sphingomyelin synthase 2
 17204
 0.13
chr14_121129398_121129725 0.30 Farp1
 FERM, RhoGEF (Arhgef) and pleckstrin domain protein 1 (chondrocyte-derived)
 27482
 0.23
chr2_163345083_163345234 0.30 Tox2
 TOX high mobility group box family member 2
 24780
 0.15
chr2_59884229_59884405 0.29 Wdsub1
 WD repeat, SAM and U-box domain containing 1
 1726
 0.39
chr5_92369721_92369887 0.29 Cxcl11
 chemokine (C-X-C motif) ligand 11
 4319
 0.12
chr5_66114850_66115151 0.29 Rbm47
 RNA binding motif protein 47
 16809
 0.11
chr2_33361310_33361488 0.29 Gm25998
 predicted gene, 25998
 1647
 0.33
chr8_121326131_121326500 0.28 Gm26815
 predicted gene, 26815
 30521
 0.17
chr15_67062566_67062733 0.28 Gm31342
 predicted gene, 31342
 22591
 0.2
chr9_46126472_46126634 0.28 Sik3
 SIK family kinase 3
 3316
 0.24
chr6_119669877_119670185 0.28 Erc1
 ELKS/RAB6-interacting/CAST family member 1
 47926
 0.16
chr3_85022833_85023030 0.28 Fbxw7
 F-box and WD-40 domain protein 7
 70785
 0.12
chr11_87448290_87448449 0.28 Rnu3b3
 U3B small nuclear RNA 3
 258
 0.81
chr4_35082276_35082489 0.27 Ifnk
 interferon kappa
 69674
 0.09
chr3_118478170_118478340 0.27 Gm26871
 predicted gene, 26871
 20596
 0.14
chr12_84161882_84162074 0.27 Elmsan1
 ELM2 and Myb/SANT-like domain containing 1
 1840
 0.21
chr18_64661052_64661203 0.26 Atp8b1
 ATPase, class I, type 8B, member 1
 140
 0.95
chr8_27197023_27197181 0.26 Got1l1
 glutamic-oxaloacetic transaminase 1-like 1
 1615
 0.23
chr8_46540344_46540495 0.25 Acsl1
 acyl-CoA synthetase long-chain family member 1
 9355
 0.15
chr4_61451087_61451318 0.25 Mup-ps12
 major urinary protein, pseudogene 12
 1042
 0.53
chr4_55014920_55015072 0.25 Zfp462
 zinc finger protein 462
 3516
 0.32
chr9_61370295_61371248 0.25 Gm10655
 predicted gene 10655
 856
 0.53
chr9_66511801_66511983 0.25 Fbxl22
 F-box and leucine-rich repeat protein 22
 2717
 0.23
chr18_53460193_53460360 0.25 Prdm6
 PR domain containing 6
 3307
 0.33
chr10_96374728_96374886 0.25 Gm48428
 predicted gene, 48428
 28983
 0.15
chr10_85193452_85193650 0.25 Cry1
 cryptochrome 1 (photolyase-like)
 8487
 0.2
chr17_3121877_3122042 0.24 Gm49798
 predicted gene, 49798
 2842
 0.14
chr5_32441483_32441679 0.24 Ppp1cb
 protein phosphatase 1 catalytic subunit beta
 17262
 0.11
chr13_80893348_80893872 0.24 Arrdc3
 arrestin domain containing 3
 3092
 0.22
chr2_152396769_152396934 0.24 Sox12
 SRY (sex determining region Y)-box 12
 1195
 0.26
chr9_20862237_20862476 0.24 Shfl
 shiftless antiviral inhibitor of ribosomal frameshifting
 6286
 0.09
chr2_152792514_152792820 0.24 Gm23802
 predicted gene, 23802
 19778
 0.11
chr9_104140474_104140634 0.23 Dnajc13
 DnaJ heat shock protein family (Hsp40) member C13
 12942
 0.11
chr13_42829016_42829414 0.23 Phactr1
 phosphatase and actin regulator 1
 37032
 0.15
chr5_135674436_135674608 0.23 Por
 P450 (cytochrome) oxidoreductase
 59
 0.94
chr5_127633759_127633922 0.23 Slc15a4
 solute carrier family 15, member 4
 943
 0.47
chr1_180161827_180161978 0.22 Cdc42bpa
 CDC42 binding protein kinase alpha
 895
 0.53
chr3_41101300_41101479 0.22 Pgrmc2
 progesterone receptor membrane component 2
 18343
 0.18
chr1_64787740_64787910 0.22 Plekhm3
 pleckstrin homology domain containing, family M, member 3
 48939
 0.1
chr13_81323663_81323834 0.22 Adgrv1
 adhesion G protein-coupled receptor V1
 19088
 0.24
chr2_90474865_90475228 0.22 Ptprj
 protein tyrosine phosphatase, receptor type, J
 3710
 0.21
chr18_64633009_64633171 0.22 Gm6978
 predicted gene 6978
 19991
 0.13
chr15_74921417_74921675 0.22 Gm6610
 predicted gene 6610
 2898
 0.13
chr5_66000185_66000354 0.21 9130230L23Rik
 RIKEN cDNA 9130230L23 gene
 51
 0.96
chr7_44748389_44748555 0.21 Vrk3
 vaccinia related kinase 3
 13
 0.55
chr4_130120889_130121053 0.21 Pef1
 penta-EF hand domain containing 1
 13415
 0.14
chr7_37961383_37961554 0.21 Uri1
 URI1, prefoldin-like chaperone
 1060
 0.6
chr1_58718073_58718224 0.20 Cflar
 CASP8 and FADD-like apoptosis regulator
 4262
 0.15
chr4_40143379_40143566 0.20 Aco1
 aconitase 1
 391
 0.86
chr15_10901895_10902215 0.20 Gm29742
 predicted gene, 29742
 15382
 0.17
chr13_62884266_62884452 0.20 Fbp1
 fructose bisphosphatase 1
 3768
 0.17
chr3_87982848_87983167 0.19 Bcan
 brevican
 11448
 0.09
chr14_30570457_30570647 0.19 Tkt
 transketolase
 847
 0.47
chr6_54792866_54793180 0.19 Znrf2
 zinc and ring finger 2
 23893
 0.19
chr2_32983682_32983870 0.19 Slc2a8
 solute carrier family 2, (facilitated glucose transporter), member 8
 1693
 0.23
chr2_103811926_103812077 0.19 Gm13878
 predicted gene 13878
 384
 0.68
chr1_134566100_134566265 0.19 Kdm5b
 lysine (K)-specific demethylase 5B
 5975
 0.14
chr4_60755643_60755889 0.19 Mup-ps8
 major urinary protein, pseudogene 8
 1046
 0.52
chr12_76927037_76927196 0.19 Max
 Max protein
 12878
 0.15
chr2_132110806_132111002 0.18 Slc23a2
 solute carrier family 23 (nucleobase transporters), member 2
 544
 0.75
chr19_47067586_47067748 0.18 Taf5
 TATA-box binding protein associated factor 5
 79
 0.94
chr11_113722506_113722673 0.18 Cpsf4l
 cleavage and polyadenylation specific factor 4-like
 12572
 0.13
chr10_13553038_13553200 0.18 Pex3
 peroxisomal biogenesis factor 3
 1
 0.75
chr13_41341555_41341714 0.18 Nedd9
 neural precursor cell expressed, developmentally down-regulated gene 9
 17613
 0.13
chr3_122293242_122293417 0.18 Gm40190
 predicted gene, 40190
 110
 0.55
chr13_90963501_90963652 0.18 Rps23
 ribosomal protein S23
 39391
 0.17
chr1_21240367_21240700 0.18 Gsta3
 glutathione S-transferase, alpha 3
 56
 0.96
chr5_146793134_146793310 0.18 Usp12
 ubiquitin specific peptidase 12
 1784
 0.25
chr5_138857853_138858235 0.17 Gm5294
 predicted gene 5294
 37964
 0.15
chr2_160871410_160871577 0.17 Zhx3
 zinc fingers and homeoboxes 3
 1079
 0.41
chr5_102483708_102483875 0.17 1700013M08Rik
 RIKEN cDNA 1700013M08 gene
 502
 0.8
chr18_20749064_20749237 0.17 B4galt6
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
 2746
 0.29
chr9_50845710_50845905 0.17 Ppp2r1b
 protein phosphatase 2, regulatory subunit A, beta
 506
 0.74
chr13_66986541_66986692 0.17 Ptdss1
 phosphatidylserine synthase 1
 6852
 0.12
chr11_50022246_50022426 0.17 Rnf130
 ring finger protein 130
 3010
 0.24
chr2_51056109_51056315 0.17 Rnd3
 Rho family GTPase 3
 92882
 0.08
chr9_96258590_96258741 0.17 Tfdp2
 transcription factor Dp 2
 40
 0.97
chr12_111547368_111547748 0.17 Eif5
 eukaryotic translation initiation factor 5
 4727
 0.12
chr11_94576436_94576618 0.16 Acsf2
 acyl-CoA synthetase family member 2
 5749
 0.12
chr16_87524872_87525038 0.16 Gm24891
 predicted gene, 24891
 3210
 0.17
chrX_168779160_168779328 0.16 Gm15233
 predicted gene 15233
 3988
 0.27
chr13_96460531_96460839 0.16 Ankdd1b
 ankyrin repeat and death domain containing 1B
 10426
 0.14
chr2_119898379_119898542 0.16 Mga
 MAX gene associated
 1155
 0.44
chr11_43992113_43992279 0.16 Gm12153
 predicted gene 12153
 33107
 0.21
chr12_8379850_8380024 0.16 Gm48075
 predicted gene, 48075
 14272
 0.16
chr1_131092973_131093137 0.15 Gm37084
 predicted gene, 37084
 906
 0.48
chr2_25224743_25224915 0.15 Tubb4b
 tubulin, beta 4B class IVB
 127
 0.85
chr17_64668680_64668845 0.15 Man2a1
 mannosidase 2, alpha 1
 44658
 0.16
chr12_86793995_86794154 0.15 Gm10095
 predicted gene 10095
 52393
 0.1
chr8_123727062_123727236 0.15 6030466F02Rik
 RIKEN cDNA 6030466F02 gene
 6809
 0.08
chrX_11574471_11574649 0.15 Gm14515
 predicted gene 14515
 26794
 0.22
chr11_83753876_83754040 0.15 Heatr6
 HEAT repeat containing 6
 71
 0.94
chr13_69577241_69577408 0.15 Srd5a1
 steroid 5 alpha-reductase 1
 17505
 0.12
chr2_167888871_167889131 0.15 Gm14319
 predicted gene 14319
 30416
 0.13
chr5_138979896_138980396 0.15 Pdgfa
 platelet derived growth factor, alpha
 14135
 0.17
chr12_21426260_21426445 0.14 Gm4419
 predicted gene 4419
 5593
 0.17
chr6_90475971_90476128 0.14 Gm44421
 predicted gene, 44421
 2417
 0.16
chr8_85493343_85493503 0.14 Gpt2
 glutamic pyruvate transaminase (alanine aminotransferase) 2
 814
 0.6
chr5_138823785_138824155 0.14 Gm5294
 predicted gene 5294
 3890
 0.23
chr2_70475906_70476144 0.13 Sp5
 trans-acting transcription factor 5
 1102
 0.41
chr19_53076271_53076445 0.13 1700054A03Rik
 RIKEN cDNA 1700054A03 gene
 106
 0.96
chr5_99526510_99527092 0.13 Gm16227
 predicted gene 16227
 16119
 0.19
chr12_3959908_3960075 0.13 Pomc
 pro-opiomelanocortin-alpha
 5021
 0.16
chr15_22046405_22046937 0.13 Gm49187
 predicted gene, 49187
 88239
 0.1
chr7_79466451_79467019 0.13 Gm10616
 predicted gene 10616
 326
 0.49
chr11_98935186_98935341 0.13 Rara
 retinoic acid receptor, alpha
 2435
 0.17
chr16_23996527_23996692 0.13 Bcl6
 B cell leukemia/lymphoma 6
 7757
 0.17
chr18_46804511_46804701 0.13 Gm49972
 predicted gene, 49972
 33281
 0.1
chr6_97278036_97278202 0.13 Frmd4b
 FERM domain containing 4B
 13142
 0.18
chr12_26401660_26402061 0.13 Rnf144a
 ring finger protein 144A
 4587
 0.18
chr2_172961302_172961478 0.13 Spo11
 SPO11 meiotic protein covalently bound to DSB
 16310
 0.15
chr10_76576688_76577047 0.13 Ftcd
 formiminotransferase cyclodeaminase
 1215
 0.33
chr11_109545590_109545763 0.13 Arsg
 arylsulfatase G
 1922
 0.3
chr2_77515804_77515970 0.13 Zfp385b
 zinc finger protein 385B
 3648
 0.32
chr6_143100150_143100314 0.13 C2cd5
 C2 calcium-dependent domain containing 5
 91
 0.96
chr15_59046761_59047065 0.12 Mtss1
 MTSS I-BAR domain containing 1
 6316
 0.23
chr5_122518398_122518573 0.12 Gm22965
 predicted gene, 22965
 11696
 0.1
chr8_120275994_120276315 0.12 Gse1
 genetic suppressor element 1, coiled-coil protein
 47698
 0.12
chr15_64195944_64196287 0.12 Asap1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain1
 12376
 0.24
chr1_36536444_36536641 0.12 Ankrd23
 ankyrin repeat domain 23
 21
 0.94
chr16_24223745_24224269 0.12 Gm31814
 predicted gene, 31814
 7483
 0.23
chr4_37093076_37093227 0.12 Taf9-ps
 TATA-box binding protein associated factor 9, pseudogene
 46723
 0.17
chr5_90464660_90465223 0.12 Alb
 albumin
 2241
 0.25
chr5_122802424_122802664 0.12 Anapc5
 anaphase-promoting complex subunit 5
 78
 0.96
chr7_83892128_83892320 0.12 Gm49493
 predicted gene, 49493
 38
 0.57
chr9_32540170_32540338 0.12 Fli1
 Friend leukemia integration 1
 1341
 0.31
chr18_34117842_34118226 0.12 Gm5238
 predicted gene 5238
 7683
 0.17
chr8_69399199_69399538 0.12 Gm25661
 predicted gene, 25661
 357
 0.82
chr2_83648966_83649145 0.11 Zc3h15
 zinc finger CCCH-type containing 15
 4432
 0.24
chr1_69634071_69634222 0.11 Gm28112
 predicted gene 28112
 27915
 0.17
chr12_112586365_112586574 0.11 Inf2
 inverted formin, FH2 and WH2 domain containing
 2315
 0.23
chr10_111795867_111796218 0.11 Gm47865
 predicted gene, 47865
 3709
 0.16
chr11_72940971_72941129 0.11 Gm44467
 predicted gene, 44467
 12057
 0.13
chr3_39944706_39944868 0.11 Gm42785
 predicted gene 42785
 121210
 0.06
chr10_75789893_75790050 0.11 Gstt1
 glutathione S-transferase, theta 1
 7598
 0.09
chr4_100377331_100377511 0.11 Gm12706
 predicted gene 12706
 15362
 0.26
chr19_47511131_47511282 0.11 Gm19557
 predicted gene, 19557
 1776
 0.29
chr13_24049473_24049634 0.11 Carmil1
 capping protein regulator and myosin 1 linker 1
 9766
 0.17
chr9_77768228_77768406 0.11 Gclc
 glutamate-cysteine ligase, catalytic subunit
 2175
 0.24
chr14_11591449_11591619 0.11 Ptprg
 protein tyrosine phosphatase, receptor type, G
 37953
 0.17
chr5_129019617_129019788 0.11 Ran
 RAN, member RAS oncogene family
 367
 0.88
chr17_46725800_46726019 0.11 Gnmt
 glycine N-methyltransferase
 793
 0.43
chr11_45178287_45178504 0.10 Gm38087
 predicted gene, 38087
 11477
 0.2
chr5_117380230_117380381 0.10 Rfc5
 replication factor C (activator 1) 5
 89
 0.95
chr19_41277479_41277665 0.10 Tm9sf3
 transmembrane 9 superfamily member 3
 13575
 0.24
chr4_60516308_60516518 0.10 Mup-ps6
 major urinary protein, pseudogene 6
 1048
 0.41
chr19_6340387_6340875 0.10 Map4k2
 mitogen-activated protein kinase kinase kinase kinase 2
 504
 0.46
chr19_41332343_41332496 0.10 Pik3ap1
 phosphoinositide-3-kinase adaptor protein 1
 52677
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Pax1_Pax9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.1 0.3 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.1 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.1 0.2 GO:0015817 histidine transport(GO:0015817)
0.1 0.2 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.1 0.2 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.5 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:1903011 negative regulation of bone development(GO:1903011)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.2 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0052041 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.1 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.1 GO:1902570 protein localization to nucleolus(GO:1902570)
0.0 0.3 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.1 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0 0.0 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.0 GO:2000591 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.2 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.2 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.0 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.0 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.0 0.2 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.1 GO:0009226 nucleotide-sugar biosynthetic process(GO:0009226)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.0 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0 0.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.0 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0006857 oligopeptide transport(GO:0006857)
0.0 0.0 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0048500 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.2 GO:0071565 nBAF complex(GO:0071565)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.2 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.0 GO:0097413 Lewy body(GO:0097413)
0.0 0.0 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.0 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.2 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 0.3 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.4 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0004802 transketolase activity(GO:0004802)
0.0 0.1 GO:0090482 vitamin transmembrane transporter activity(GO:0090482)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0008312 7S RNA binding(GO:0008312)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0030955 potassium ion binding(GO:0030955)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.0 GO:0034548 N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.3 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0031432 titin binding(GO:0031432)
0.0 0.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.0 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.1 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.0 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.2 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation