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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Pbx1_Pbx3

Z-value: 2.64

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Transcription factors associated with Pbx1_Pbx3

Gene Symbol	Gene ID	Gene Info
Pbx1 Ensembl NCBI MGI UniProt	ENSMUSG00000052534.9	pre B cell leukemia homeobox 1
Pbx3 Ensembl NCBI MGI UniProt	ENSMUSG00000038718.9	pre B cell leukemia homeobox 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr1_168432437_168432592	Pbx1	244	0.948903	0.87	2.3e-02	Click!
chr1_168431789_168431974	Pbx1	16	0.985092	-0.70	1.2e-01	Click!
chr1_168459622_168459790	Pbx1	27436	0.198212	0.67	1.4e-01	Click!
chr1_168243189_168243345	Pbx1	78605	0.102027	0.64	1.7e-01	Click!
chr1_168242978_168243129	Pbx1	78391	0.102431	-0.60	2.0e-01	Click!
chr2_34371764_34371916	Pbx3	48	0.976597	0.76	8.2e-02	Click!
chr2_34372642_34372966	Pbx3	338	0.885178	0.71	1.1e-01	Click!
chr2_34373141_34373311	Pbx3	84	0.972022	0.70	1.2e-01	Click!
chr2_34373406_34373602	Pbx3	362	0.872757	-0.53	2.8e-01	Click!
chr2_34289834_34289999	Pbx3	1064	0.502800	-0.48	3.3e-01	Click!

Activity of the Pbx1_Pbx3 motif across conditions

Conditions sorted by the z-value of the Pbx1_Pbx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_36731141_36731447	2.33	Ppp1r3c	protein phosphatase 1, regulatory subunit 3C	5359	0.23
chr19_45745506_45745808	2.32	Fgf8	fibroblast growth factor 8	2742	0.18
chr5_117245335_117245486	2.24	Taok3	TAO kinase 3	4950	0.16
chr13_65240528_65240714	2.23	Gm36445	predicted gene, 36445	1132	0.26
chr5_120643717_120643868	2.10	Gm42657	predicted gene 42657	2171	0.14
chr17_37995732_37995883	2.02	Gm20541	predicted gene 20541	13840	0.1
chr3_8891989_8892146	1.92	Gm15466	predicted gene 15466	9497	0.17
chr10_66305359_66305513	1.79	1700023F02Rik	RIKEN cDNA 1700023F02 gene	51213	0.17
chr2_153660708_153660867	1.61	Dnmt3b	DNA methyltransferase 3B	5015	0.17
chr18_46336206_46336490	1.58	4930415P13Rik	RIKEN cDNA 4930415P13 gene	4081	0.17
chr4_26470101_26470279	1.48	Gm11903	predicted gene 11903	27729	0.19
chr8_91134020_91134367	1.46	Aktip	thymoma viral proto-oncogene 1 interacting protein	166	0.92
chr11_113725569_113725747	1.40	Cdc42ep4	CDC42 effector protein (Rho GTPase binding) 4	13664	0.13
chr8_126847749_126848310	1.38	A630001O12Rik	RIKEN cDNA A630001O12 gene	8796	0.2
chr12_21168361_21168533	1.38	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	56493	0.1
chr9_43593249_43593421	1.36	Gm29909	predicted gene, 29909	14849	0.18
chr8_119417830_119417981	1.31	Osgin1	oxidative stress induced growth inhibitor 1	16219	0.14
chr1_181002507_181002700	1.30	Ephx1	epoxide hydrolase 1, microsomal	6433	0.1
chr16_23964206_23964416	1.29	Bcl6	B cell leukemia/lymphoma 6	8069	0.17
chr15_89227137_89227295	1.28	Ppp6r2	protein phosphatase 6, regulatory subunit 2	15615	0.1
chr12_109993740_109993939	1.24	Gm34667	predicted gene, 34667	30034	0.1
chr19_12488282_12488454	1.19	Dtx4	deltex 4, E3 ubiquitin ligase	13086	0.1
chr1_9584205_9584668	1.17	Gm6161	predicted gene 6161	9888	0.13
chr12_110219862_110220027	1.17	Gm40576	predicted gene, 40576	16418	0.11
chr15_82147771_82148080	1.17	Srebf2	sterol regulatory element binding factor 2	88	0.94
chr10_8195740_8196032	1.15	Gm30906	predicted gene, 30906	19755	0.25
chr10_93519889_93520065	1.14	Hal	histidine ammonia lyase	18852	0.12
chr13_93627456_93627944	1.08	Gm15622	predicted gene 15622	2318	0.25
chr19_43769806_43769959	1.06	Cutc	cutC copper transporter	5009	0.15
chr2_60947339_60947519	1.05	Rbms1	RNA binding motif, single stranded interacting protein 1	15763	0.22
chr4_148060264_148060415	1.04	Mthfr	methylenetetrahydrofolate reductase	7661	0.09
chr3_107943742_107943913	1.04	Gstm6	glutathione S-transferase, mu 6	78	0.92
chr8_12719084_12719404	1.03	Gm15348	predicted gene 15348	117	0.96
chr12_88472970_88473131	1.00	Gm48642	predicted gene, 48642	30718	0.1
chr1_35878619_35878782	0.99	1110002O04Rik	RIKEN cDNA 1110002O04 gene	1145	0.54
chr10_79877307_79877478	0.99	Prtn3	proteinase 3	2222	0.09
chr12_73300604_73300762	0.98	Slc38a6	solute carrier family 38, member 6	13623	0.17
chr19_23060777_23060935	0.96	Gm50136	predicted gene, 50136	598	0.75
chr7_132555520_132555801	0.96	Oat	ornithine aminotransferase	20058	0.15
chr17_45585371_45585529	0.95	Gm17080	predicted gene 17080	670	0.48
chr10_81555544_81555695	0.95	Tle5	TLE family member 5, transcriptional modulator	3869	0.09
chr10_95440765_95440927	0.95	Gm47600	predicted gene, 47600	14120	0.11
chr16_23026654_23026981	0.95	Kng2	kininogen 2	2192	0.15
chr8_69463588_69463766	0.95	Gm45850	predicted gene 45850	6392	0.13
chr10_61278018_61278535	0.93	Adamts14	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14	4838	0.17
chr2_170209557_170209769	0.93	Zfp217	zinc finger protein 217	61560	0.12
chr1_88975960_88976113	0.93	1700067G17Rik	RIKEN cDNA 1700067G17 gene	40077	0.14
chr11_109486119_109486495	0.90	Arsg	arylsulfatase G	701	0.57
chr5_8985691_8985842	0.89	Crot	carnitine O-octanoyltransferase	3622	0.15
chr4_149793786_149793938	0.89	Gm13065	predicted gene 13065	443	0.69
chr11_72243451_72243602	0.87	1700051A21Rik	RIKEN cDNA 1700051A21 gene	22895	0.09
chr17_31564751_31564906	0.87	Pknox1	Pbx/knotted 1 homeobox	12	0.7
chr8_33793351_33793524	0.86	Rbpms	RNA binding protein gene with multiple splicing	3777	0.18
chr6_83121491_83121654	0.86	Wbp1	WW domain binding protein 1	13	0.89
chr5_73490776_73490935	0.86	Dcun1d4	DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)	170	0.94
chr3_108680974_108681157	0.85	Clcc1	chloride channel CLIC-like 1	13214	0.12
chr10_61340373_61340533	0.84	Pald1	phosphatase domain containing, paladin 1	1874	0.24
chr19_36702220_36702413	0.84	Hectd2os	Hectd2, opposite strand	3325	0.28
chr19_43971247_43971535	0.83	Cpn1	carboxypeptidase N, polypeptide 1	2698	0.21
chr12_76710114_76710283	0.83	Sptb	spectrin beta, erythrocytic	175	0.95
chr15_53316381_53316532	0.82	Ext1	exostosin glycosyltransferase 1	29203	0.23
chr13_73034720_73034871	0.81	Rpl31-ps2	ribosomal protein L31, pseudogene 2	198600	0.02
chr5_113207031_113207205	0.81	2900026A02Rik	RIKEN cDNA 2900026A02 gene	14118	0.13
chr4_118499414_118499578	0.81	Gm12859	predicted gene 12859	1854	0.2
chr17_35251426_35251588	0.80	Mir8094	microRNA 8094	218	0.76
chr14_17863991_17864161	0.80	Gm48320	predicted gene, 48320	92954	0.08
chr8_69533176_69533363	0.80	Rps7-ps1	ribosomal protein S7, pseudogene 1	7688	0.14
chr15_78174169_78174404	0.80	Gm49694	predicted gene, 49694	175	0.49
chr2_145703456_145703623	0.79	Gm11763	predicted gene 11763	1814	0.34
chr3_37902815_37902966	0.79	Gm20755	predicted gene, 20755	4077	0.21
chr8_124750214_124750687	0.78	Fam89a	family with sequence similarity 89, member A	1382	0.3
chr10_83326919_83327146	0.78	Slc41a2	solute carrier family 41, member 2	4149	0.19
chr14_61037704_61037855	0.78	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	112	0.6
chr15_63616648_63616825	0.78	Gm5473	predicted pseudogene 5473	14961	0.21
chr10_75079699_75079850	0.77	Bcr	BCR activator of RhoGEF and GTPase	19182	0.16
chr9_69306275_69306692	0.77	Rora	RAR-related orphan receptor alpha	16801	0.21
chr10_8448053_8448204	0.76	Ust	uronyl-2-sulfotransferase	70697	0.12
chr3_57344959_57345117	0.76	Gm5276	predicted gene 5276	17350	0.19
chr7_30353715_30354115	0.76	4930479H17Rik	RIKEN cDNA 4930479H17 gene	594	0.46
chr17_34603624_34603938	0.75	Rnf5	ring finger protein 5	91	0.8
chr7_141475336_141475516	0.75	Tspan4	tetraspanin 4	84	0.73
chr10_18401012_18401316	0.75	Nhsl1	NHS-like 1	6474	0.25
chr15_100659267_100659476	0.74	Bin2	bridging integrator 2	7711	0.09
chr7_35146051_35146625	0.73	Gm35665	predicted gene, 35665	4889	0.12
chr11_96830023_96830181	0.73	Nfe2l1	nuclear factor, erythroid derived 2,-like 1	134	0.92
chr8_18217240_18217405	0.73	Gm25665	predicted gene, 25665	57499	0.16
chr2_122765578_122765773	0.72	Sqor	sulfide quinone oxidoreductase	266	0.9
chr8_119426736_119426920	0.72	Osgin1	oxidative stress induced growth inhibitor 1	7296	0.15
chr2_32752327_32752485	0.72	Tor2a	torsin family 2, member A	4828	0.08
chr17_55891942_55892103	0.71	Zfp959	zinc finger protein 959	71	0.95
chr16_91146000_91146151	0.71	Gm49612	predicted gene, 49612	10599	0.1
chr12_109989506_109989657	0.71	Gm34667	predicted gene, 34667	34292	0.1
chr2_25472663_25472828	0.70	Ptgds	prostaglandin D2 synthase (brain)	2699	0.1
chr8_69749926_69750089	0.70	Zfp963	zinc finger protein 963	37	0.96
chr18_46717220_46717635	0.70	Cdo1	cysteine dioxygenase 1, cytosolic	10602	0.13
chr10_82354132_82354306	0.69	Gm4924	predicted gene 4924	36	0.98
chr2_158302944_158303106	0.69	Lbp	lipopolysaccharide binding protein	3468	0.15
chr11_78886844_78887001	0.69	Nos2	nitric oxide synthase 2, inducible	33865	0.14
chr2_116065184_116065343	0.69	Meis2	Meis homeobox 2	216	0.9
chr17_28280110_28280287	0.69	Ppard	peroxisome proliferator activator receptor delta	8079	0.11
chr17_48002012_48002364	0.68	Gm14871	predicted gene 14871	1384	0.35
chr19_41981401_41981614	0.68	Ubtd1	ubiquitin domain containing 1	256	0.57
chr13_48871990_48872151	0.68	Phf2	PHD finger protein 2	951	0.4
chr8_48729447_48729608	0.68	Tenm3	teneurin transmembrane protein 3	54837	0.15
chr6_145679594_145679775	0.68	Tuba3b	tubulin, alpha 3B	63927	0.09
chr9_41852406_41852580	0.67	AC160966.1	novel transcript	23058	0.14
chr1_7397892_7398056	0.67	Gm26901	predicted gene, 26901	105	0.97
chr8_116287814_116287976	0.67	1700018P08Rik	RIKEN cDNA 1700018P08 gene	69166	0.12
chr6_100452431_100452603	0.67	Gm23234	predicted gene, 23234	42297	0.14
chr2_165824935_165825092	0.67	Zmynd8	zinc finger, MYND-type containing 8	27109	0.14
chr4_135265584_135265749	0.67	Clic4	chloride intracellular channel 4 (mitochondrial)	7148	0.15
chr8_20024505_20024705	0.66	Gm45754	predicted gene 45754	5194	0.19
chr1_64792479_64792657	0.66	Plekhm3	pleckstrin homology domain containing, family M, member 3	44196	0.12
chr14_16365010_16365174	0.66	Top2b	topoisomerase (DNA) II beta	87	0.95
chr15_83464652_83464817	0.66	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	128	0.95
chr12_76269373_76269531	0.66	Gm47526	predicted gene, 47526	8264	0.12
chr19_37534231_37534391	0.66	Exoc6	exocyst complex component 6	13432	0.19
chr3_88339093_88339486	0.66	Smg5	Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)	1431	0.18
chr11_117310974_117311216	0.65	Septin9	septin 9	2941	0.27
chr11_114989903_114990054	0.65	Cd300ld	CD300 molecule like family member d	56	0.95
chr1_119217442_119217613	0.65	Gm3508	predicted gene 3508	25226	0.19
chr19_5816088_5816252	0.65	Gm27702	predicted gene, 27702	8537	0.07
chr17_22867078_22867262	0.65	Zfp945	zinc finger protein 945	36	0.97
chr1_194610747_194610948	0.65	Plxna2	plexin A2	7371	0.21
chr4_34964989_34965150	0.65	Gm12364	predicted gene 12364	2849	0.23
chr9_63702505_63702656	0.65	Smad3	SMAD family member 3	9389	0.23
chr13_96432101_96432337	0.64	Ankdd1b	ankyrin repeat and death domain containing 1B	3733	0.19
chrX_56606636_56606787	0.64	Slc9a6	solute carrier family 9 (sodium/hydrogen exchanger), member 6	3046	0.2
chr15_100121547_100121719	0.64	4930478M13Rik	RIKEN cDNA 4930478M13 gene	13472	0.14
chr10_68435870_68436036	0.64	Cabcoco1	ciliary associated calcium binding coiled-coil 1	89814	0.08
chr17_50508799_50508969	0.64	Plcl2	phospholipase C-like 2	519	0.87
chr14_57089246_57089418	0.63	Gjb2	gap junction protein, beta 2	15370	0.14
chr1_93146606_93146776	0.63	Agxt	alanine-glyoxylate aminotransferase	6812	0.13
chr10_80260010_80260177	0.63	Gamt	guanidinoacetate methyltransferase	804	0.32
chr4_151044647_151045045	0.62	Per3	period circadian clock 3	181	0.94
chr10_86069565_86069729	0.62	Syn3	synapsin III	2804	0.18
chr1_136700890_136701078	0.61	Gm24086	predicted gene, 24086	3610	0.16
chr17_24443544_24443715	0.61	Dnase1l2	deoxyribonuclease 1-like 2	524	0.46
chr4_141742037_141742199	0.61	Agmat	agmatine ureohydrolase (agmatinase)	4554	0.14
chr11_94281536_94281687	0.61	Gm21885	predicted gene, 21885	262	0.9
chr10_34136560_34136736	0.61	Calhm6	calcium homeostasis modulator family member 6	8664	0.13
chr12_80598944_80599110	0.60	Galnt16	polypeptide N-acetylgalactosaminyltransferase 16	924	0.35
chr4_53315243_53315405	0.60	Gm12495	predicted gene 12495	7098	0.21
chr3_81034660_81034949	0.60	Pdgfc	platelet-derived growth factor, C polypeptide	1612	0.29
chr4_46988359_46988517	0.59	Gabbr2	gamma-aminobutyric acid (GABA) B receptor, 2	3435	0.22
chr11_80209518_80209681	0.59	Rhot1	ras homolog family member T1	452	0.79
chr8_20604704_20604862	0.58	Gm21112	predicted gene, 21112	7742	0.17
chr7_6838397_6838557	0.58	Gm44584	predicted gene 44584	29476	0.1
chr6_16506632_16506807	0.58	Gm36406	predicted gene, 36406	36769	0.19
chr8_46386589_46386784	0.58	Gm45253	predicted gene 45253	798	0.57
chr15_70451376_70451558	0.58	Gm18155	predicted gene, 18155	306586	0.01
chr3_108778882_108779033	0.58	Aknad1	AKNA domain containing 1	18743	0.13
chr14_22800645_22800832	0.58	Gm7473	predicted gene 7473	25494	0.25
chr7_6728225_6728524	0.58	Peg3	paternally expressed 3	2045	0.16
chr13_45906518_45907031	0.57	4930453C13Rik	RIKEN cDNA 4930453C13 gene	29266	0.18
chr12_82324664_82324830	0.57	Sipa1l1	signal-induced proliferation-associated 1 like 1	13398	0.27
chr10_81863776_81863946	0.57	Gm32687	predicted gene, 32687	73	0.94
chr5_137076213_137076385	0.57	Serpine1	serine (or cysteine) peptidase inhibitor, clade E, member 1	4031	0.13
chr10_81996886_81997052	0.57	Gm8158	predicted gene 8158	10567	0.09
chr10_81704670_81704836	0.57	Zfp433	zinc finger protein 433	72	0.93
chr7_39449322_39449487	0.57	Zfp939	zinc finger protein 939	114	0.59
chr17_13711329_13711480	0.57	Tcte2	t-complex-associated testis expressed 2	21494	0.13
chr15_78424614_78424801	0.57	Gm36644	predicted gene, 36644	514	0.62
chr1_55363742_55363908	0.57	Boll	boule homolog, RNA binding protein	356	0.82
chr2_120978246_120978599	0.56	Gm44325	predicted gene, 44325	695	0.38
chr17_4941398_4941549	0.56	Gm41517	predicted gene, 41517	5341	0.24
chr10_84060915_84061106	0.56	Gm37908	predicted gene, 37908	748	0.67
chr3_104762311_104762636	0.56	Gm6485	predicted gene 6485	9308	0.09
chr19_55266477_55266642	0.56	Acsl5	acyl-CoA synthetase long-chain family member 5	6311	0.18
chr12_54192050_54192209	0.56	Egln3	egl-9 family hypoxia-inducible factor 3	11731	0.17
chr10_93623829_93624021	0.56	Gm47156	predicted gene, 47156	5063	0.14
chr17_60509248_60509418	0.55	Gm4512	predicted gene 4512	18791	0.22
chr5_52916317_52916477	0.55	Gm43664	predicted gene 43664	2812	0.25
chr6_136467177_136467328	0.55	Gm6728	predicted gene 6728	19934	0.11
chr17_3557456_3557629	0.55	Tfb1m	transcription factor B1, mitochondrial	192	0.61
chr13_34719995_34720155	0.55	Gm47152	predicted gene, 47152	607	0.42
chr16_10976237_10976411	0.55	Litaf	LPS-induced TN factor	745	0.51
chr4_103387600_103387901	0.55	Gm12718	predicted gene 12718	5229	0.23
chr12_80707277_80707456	0.55	Plekhd1	pleckstrin homology domain containing, family D (with coiled-coil domains) member 1	520	0.67
chr15_25945393_25945754	0.54	Mir7212	microRNA 7212	2654	0.25
chr3_96600934_96601103	0.54	Lix1l	Lix1-like	131	0.88
chr8_126595451_126595638	0.54	Irf2bp2	interferon regulatory factor 2 binding protein 2	1558	0.45
chr2_177032448_177032667	0.54	Gm14402	predicted gene 14402	98	0.95
chr12_54671337_54671527	0.54	Gm24971	predicted gene, 24971	4646	0.08
chr5_112134275_112134433	0.54	1700016B01Rik	RIKEN cDNA 1700016B01 gene	21883	0.18
chr13_41226845_41227201	0.54	Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	6618	0.12
chr15_77746128_77746463	0.54	Gm49410	predicted gene, 49410	5534	0.11
chr2_34905239_34905414	0.54	Phf19	PHD finger protein 19	419	0.73
chr4_44994891_44995176	0.54	Grhpr	glyoxylate reductase/hydroxypyruvate reductase	13533	0.1
chr17_15564352_15564514	0.54	Prdm9	PR domain containing 9	79	0.94
chr10_82127891_82128053	0.54	AU041133	expressed sequence AU041133	41	0.96
chr5_64459913_64460081	0.54	1700027F09Rik	RIKEN cDNA 1700027F09 gene	7946	0.13
chr13_95675299_95675472	0.54	Iqgap2	IQ motif containing GTPase activating protein 2	3866	0.17
chr11_117880814_117880965	0.54	Tha1	threonine aldolase 1	7408	0.1
chr16_22436162_22436319	0.53	Etv5	ets variant 5	274	0.91
chr2_6213212_6213379	0.53	Echdc3	enoyl Coenzyme A hydratase domain containing 3	262	0.91
chr2_32727484_32727647	0.53	Sh2d3c	SH2 domain containing 3C	141	0.88
chr8_76902033_76902222	0.53	Nr3c2	nuclear receptor subfamily 3, group C, member 2	161	0.94
chr9_31354138_31354577	0.53	Nfrkb	nuclear factor related to kappa B binding protein	31835	0.13
chr15_100414144_100414311	0.53	Gm5475	predicted gene 5475	7920	0.11

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pbx1_Pbx3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.2	0.7	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.2	0.5	GO:0010520	regulation of reciprocal meiotic recombination(GO:0010520)
0.2	0.5	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.2	0.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2	0.5	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.2	0.5	GO:0060700	regulation of ribonuclease activity(GO:0060700)
0.2	0.5	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.4	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.1	0.4	GO:0048382	mesendoderm development(GO:0048382)
0.1	0.7	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.6	GO:0070836	caveola assembly(GO:0070836)
0.1	0.4	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.1	0.4	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.6	GO:0071712	ER-associated misfolded protein catabolic process(GO:0071712)
0.1	0.5	GO:0010529	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1	0.1	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	0.3	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.1	0.8	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	0.3	GO:0045163	clustering of voltage-gated potassium channels(GO:0045163)
0.1	0.6	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1	0.2	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.6	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.3	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.1	0.6	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.2	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.5	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	0.3	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.5	GO:0001842	neural fold formation(GO:0001842)
0.1	0.3	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.3	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1	0.6	GO:0061087	positive regulation of histone H3-K27 methylation(GO:0061087)
0.1	0.3	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.1	0.2	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.3	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.1	0.2	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.1	0.3	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.7	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.1	0.7	GO:0032909	transforming growth factor beta2 production(GO:0032906) regulation of transforming growth factor beta2 production(GO:0032909)
0.1	0.2	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.1	0.4	GO:0008295	spermidine biosynthetic process(GO:0008295)
0.1	0.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.5	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.2	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.3	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.1	0.3	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.1	0.5	GO:0031033	myosin filament organization(GO:0031033)
0.1	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.1	0.3	GO:0009756	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.1	0.3	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.1	0.2	GO:0001543	ovarian follicle rupture(GO:0001543)
0.1	0.3	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.3	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.1	0.2	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.1	0.2	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.1	0.1	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.1	0.8	GO:0045116	protein neddylation(GO:0045116)
0.1	0.6	GO:0070269	pyroptosis(GO:0070269)
0.1	0.3	GO:0080009	mRNA methylation(GO:0080009)
0.1	0.2	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.1	0.2	GO:0034214	protein hexamerization(GO:0034214)
0.1	0.2	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.1	0.2	GO:0015744	succinate transport(GO:0015744)
0.1	0.3	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.1	0.1	GO:0033058	directional locomotion(GO:0033058)
0.1	0.1	GO:0032439	endosome localization(GO:0032439)
0.1	0.2	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.1	1.8	GO:0007032	endosome organization(GO:0007032)
0.1	0.5	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.1	0.2	GO:2000327	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1	0.2	GO:0061092	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.2	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.4	GO:0047497	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.1	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.1	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.1	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.3	GO:0015825	L-serine transport(GO:0015825)
0.0	0.2	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.4	GO:0023035	CD40 signaling pathway(GO:0023035)
0.0	0.1	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.2	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.3	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.3	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.3	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:1902896	terminal web assembly(GO:1902896)
0.0	0.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.2	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.0	GO:2000389	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.2	GO:1900864	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.1	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.0	0.2	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.3	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.2	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.4	GO:0070828	heterochromatin organization(GO:0070828)
0.0	0.0	GO:0090009	primitive streak formation(GO:0090009)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.5	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.2	GO:0045630	positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0	0.1	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.2	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.3	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.2	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.2	GO:0051918	negative regulation of fibrinolysis(GO:0051918)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0010760	negative regulation of macrophage chemotaxis(GO:0010760)
0.0	0.1	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.2	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.3	GO:1903624	regulation of apoptotic DNA fragmentation(GO:1902510) regulation of DNA catabolic process(GO:1903624)
0.0	0.1	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.1	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.5	GO:0009303	rRNA transcription(GO:0009303)
0.0	0.2	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.3	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.4	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.2	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0003166	bundle of His development(GO:0003166)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:1904431	positive regulation of t-circle formation(GO:1904431)
0.0	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.4	GO:0032525	somite rostral/caudal axis specification(GO:0032525)
0.0	0.1	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.4	GO:0040023	establishment of nucleus localization(GO:0040023)
0.0	0.1	GO:2001184	positive regulation of interleukin-12 secretion(GO:2001184)
0.0	0.1	GO:0002572	pro-T cell differentiation(GO:0002572)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.2	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.0	GO:0021785	branchiomotor neuron axon guidance(GO:0021785)
0.0	0.1	GO:1903998	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.0	0.4	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.1	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.0	GO:0072674	multinuclear osteoclast differentiation(GO:0072674)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.8	GO:0051693	actin filament capping(GO:0051693)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115)
0.0	0.1	GO:0070428	regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070428)
0.0	0.2	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.4	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0071233	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.1	GO:0006235	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.1	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.1	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0090232	positive regulation of spindle checkpoint(GO:0090232)
0.0	0.4	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.4	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	0.1	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.3	GO:0046697	decidualization(GO:0046697)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.4	GO:0043171	peptide catabolic process(GO:0043171)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.0	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.3	GO:0051205	protein insertion into membrane(GO:0051205)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.0	GO:0003180	aortic valve development(GO:0003176) aortic valve morphogenesis(GO:0003180)
0.0	0.0	GO:1903679	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0	0.0	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.3	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.0	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0044793	negative regulation by host of viral process(GO:0044793)
0.0	0.2	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.3	GO:0016226	iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0	0.2	GO:0070970	interleukin-2 secretion(GO:0070970)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.2	GO:0072539	T-helper 17 cell differentiation(GO:0072539)
0.0	0.2	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.0	GO:0045654	positive regulation of megakaryocyte differentiation(GO:0045654)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.0	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.1	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:0046125	pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.1	GO:0014831	gastro-intestinal system smooth muscle contraction(GO:0014831)
0.0	0.0	GO:0050705	regulation of interleukin-1 alpha secretion(GO:0050705)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.0	GO:1905206	positive regulation of response to reactive oxygen species(GO:1901033) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.4	GO:0043552	positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0	0.1	GO:0014824	artery smooth muscle contraction(GO:0014824)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0061101	neuroendocrine cell differentiation(GO:0061101)
0.0	0.1	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0036394	amylase secretion(GO:0036394)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.0	GO:0042117	monocyte activation(GO:0042117)
0.0	0.5	GO:0050802	circadian sleep/wake cycle, sleep(GO:0050802)
0.0	0.1	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0032736	positive regulation of interleukin-13 production(GO:0032736)
0.0	0.1	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.0	0.0	GO:1902302	regulation of potassium ion export(GO:1902302)
0.0	0.3	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.1	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.0	GO:0035740	CD8-positive, alpha-beta T cell proliferation(GO:0035740)
0.0	0.3	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.0	GO:0046881	positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:0010991	regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.3	GO:0007413	axonal fasciculation(GO:0007413)
0.0	0.0	GO:0032829	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0	0.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.2	GO:0016973	poly(A)+ mRNA export from nucleus(GO:0016973)
0.0	0.1	GO:0002693	positive regulation of cellular extravasation(GO:0002693)
0.0	0.2	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.1	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:2000110	negative regulation of macrophage apoptotic process(GO:2000110)
0.0	0.1	GO:0060024	rhythmic synaptic transmission(GO:0060024)
0.0	0.0	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0071351	cellular response to interleukin-18(GO:0071351)
0.0	0.1	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.3	GO:0006308	DNA catabolic process(GO:0006308)
0.0	0.0	GO:0070384	Harderian gland development(GO:0070384)
0.0	0.0	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.0	0.2	GO:0016322	neuron remodeling(GO:0016322)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.0	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.2	GO:0008340	determination of adult lifespan(GO:0008340)
0.0	0.5	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.1	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.3	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.3	GO:0000154	rRNA modification(GO:0000154)
0.0	0.0	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.0	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0	0.0	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.4	GO:0018279	protein N-linked glycosylation via asparagine(GO:0018279)
0.0	0.3	GO:0033522	histone H2A ubiquitination(GO:0033522)
0.0	0.0	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.0	GO:1903116	positive regulation of actin filament-based movement(GO:1903116)
0.0	0.0	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0010898	positive regulation of triglyceride catabolic process(GO:0010898)
0.0	0.1	GO:0006054	N-acetylneuraminate metabolic process(GO:0006054)
0.0	0.1	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.1	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.3	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0000098	sulfur amino acid catabolic process(GO:0000098)
0.0	0.1	GO:1905208	negative regulation of cardiocyte differentiation(GO:1905208)
0.0	0.0	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.2	GO:0090026	positive regulation of monocyte chemotaxis(GO:0090026)
0.0	0.1	GO:0060213	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0	0.0	GO:0045820	negative regulation of glycolytic process(GO:0045820)
0.0	0.1	GO:1903392	negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0	0.1	GO:0030432	peristalsis(GO:0030432)
0.0	0.1	GO:0002031	G-protein coupled receptor internalization(GO:0002031)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:2000035	regulation of stem cell division(GO:2000035)
0.0	1.1	GO:0030218	erythrocyte differentiation(GO:0030218)
0.0	0.0	GO:0002361	CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0	0.0	GO:0090343	positive regulation of cell aging(GO:0090343)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.2	GO:0097352	autophagosome maturation(GO:0097352) vacuole fusion(GO:0097576)
0.0	0.0	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.0	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.0	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.0	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.0	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0045955	negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0	0.1	GO:0072321	chaperone-mediated protein transport(GO:0072321)
0.0	0.1	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.7	GO:0031338	regulation of vesicle fusion(GO:0031338)
0.0	0.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.0	GO:0033602	negative regulation of dopamine secretion(GO:0033602)
0.0	0.0	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.0	GO:0072173	metanephric tubule morphogenesis(GO:0072173)
0.0	0.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.0	GO:0060160	negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.0	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.0	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0035162	embryonic hemopoiesis(GO:0035162)
0.0	0.0	GO:0007060	male meiosis chromosome segregation(GO:0007060)
0.0	0.0	GO:0090168	Golgi reassembly(GO:0090168)
0.0	0.1	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.2	GO:0045974	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.0	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.1	GO:0019336	phenol-containing compound catabolic process(GO:0019336)
0.0	0.0	GO:0032351	negative regulation of hormone metabolic process(GO:0032351) negative regulation of hormone biosynthetic process(GO:0032353)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.4	GO:0000462	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0	0.1	GO:0030220	platelet formation(GO:0030220)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.3	GO:0090102	cochlea development(GO:0090102)
0.0	0.1	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.5	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.0	GO:0061046	regulation of branching involved in lung morphogenesis(GO:0061046)
0.0	0.0	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.1	GO:0051900	mitochondrial depolarization(GO:0051882) regulation of mitochondrial depolarization(GO:0051900)
0.0	0.0	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.0	GO:1905214	regulation of mRNA binding(GO:1902415) positive regulation of mRNA binding(GO:1902416) regulation of RNA binding(GO:1905214) positive regulation of RNA binding(GO:1905216)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.0	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.1	GO:0010388	protein deneddylation(GO:0000338) cullin deneddylation(GO:0010388)
0.0	0.0	GO:0061550	cranial ganglion development(GO:0061550) trigeminal ganglion development(GO:0061551) regulation of ureteric bud formation(GO:0072106) positive regulation of ureteric bud formation(GO:0072107)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0008535	respiratory chain complex IV assembly(GO:0008535)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.0	GO:2001135	regulation of endocytic recycling(GO:2001135)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.4	GO:0008542	visual learning(GO:0008542)
0.0	0.0	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.0	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.2	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.0	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.0	GO:0071169	establishment of protein localization to chromatin(GO:0071169)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.1	GO:0072348	sulfur compound transport(GO:0072348)
0.0	0.1	GO:1902287	semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0	0.1	GO:0071420	cellular response to histamine(GO:0071420)
0.0	0.0	GO:1900094	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.0	GO:0090656	t-circle formation(GO:0090656)
0.0	0.0	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.0	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.0	GO:0071639	positive regulation of monocyte chemotactic protein-1 production(GO:0071639)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.0	GO:2000551	regulation of T-helper 2 cell cytokine production(GO:2000551)
0.0	0.1	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0009086	methionine biosynthetic process(GO:0009086)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.0	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133) pyrimidine nucleoside catabolic process(GO:0046135)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.3	1.3	GO:0070695	FHF complex(GO:0070695)
0.2	0.8	GO:0008091	spectrin(GO:0008091)
0.1	0.4	GO:0005945	6-phosphofructokinase complex(GO:0005945)
0.1	0.5	GO:0097169	AIM2 inflammasome complex(GO:0097169)
0.1	0.5	GO:1990246	uniplex complex(GO:1990246)
0.1	0.4	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	0.4	GO:0031262	Ndc80 complex(GO:0031262)
0.1	0.2	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.1	0.3	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.2	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.7	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.1	0.5	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0033503	HULC complex(GO:0033503)
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.1	0.2	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1	0.7	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.1	0.4	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.2	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.3	GO:0000796	condensin complex(GO:0000796)
0.0	0.2	GO:0071817	MMXD complex(GO:0071817)
0.0	0.2	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.3	GO:0042382	paraspeckles(GO:0042382)
0.0	0.2	GO:0033063	Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0	0.4	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.1	GO:0030897	HOPS complex(GO:0030897)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.3	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.5	GO:0090568	NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.9	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.1	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.2	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.3	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.8	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.3	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.3	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.4	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.3	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.2	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.4	GO:0097225	sperm midpiece(GO:0097225)
0.0	0.4	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.0	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.5	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.3	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.0	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.2	GO:0042589	zymogen granule membrane(GO:0042589)
0.0	0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.0	GO:0000792	heterochromatin(GO:0000792)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0008274	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.0	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0032133	chromosome passenger complex(GO:0032133)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0000145	exocyst(GO:0000145)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0097346	INO80-type complex(GO:0097346)
0.0	0.2	GO:0005922	connexon complex(GO:0005922)
0.0	0.7	GO:0031594	neuromuscular junction(GO:0031594)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.4	GO:0010494	cytoplasmic stress granule(GO:0010494)
0.0	0.0	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.0	GO:0036195	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.3	GO:0032040	small-subunit processome(GO:0032040)
0.0	0.5	GO:0005776	autophagosome(GO:0005776)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.0	GO:0000015	phosphopyruvate hydratase complex(GO:0000015)
0.0	0.1	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0016514	SWI/SNF complex(GO:0016514)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2	0.5	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1	0.4	GO:0003872	6-phosphofructokinase activity(GO:0003872)
0.1	0.4	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.4	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	0.6	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1	0.4	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1	0.3	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.4	GO:0005250	A-type (transient outward) potassium channel activity(GO:0005250)
0.1	0.5	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1	0.2	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.1	0.5	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1	0.8	GO:0097602	cullin family protein binding(GO:0097602)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.5	GO:0008494	translation activator activity(GO:0008494)
0.1	0.2	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.6	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1	0.2	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	0.2	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.3	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.5	GO:0043522	leucine zipper domain binding(GO:0043522)
0.1	0.2	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.1	0.2	GO:0019808	polyamine binding(GO:0019808)
0.1	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.2	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.2	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.1	0.2	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.1	0.3	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.4	GO:0008046	axon guidance receptor activity(GO:0008046)
0.1	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.1	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.2	GO:0032767	copper-dependent protein binding(GO:0032767)
0.1	0.2	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.1	0.7	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.1	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.8	GO:0008143	poly(A) binding(GO:0008143)
0.0	1.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.4	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.4	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.3	GO:0018471	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.2	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.3	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.3	GO:0000014	single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.3	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.4	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.5	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0070095	fructose-6-phosphate binding(GO:0070095)
0.0	0.3	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.3	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.0	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.3	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0031433	telethonin binding(GO:0031433)
0.0	0.3	GO:0022889	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.5	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.2	GO:0000150	recombinase activity(GO:0000150)
0.0	0.1	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.9	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.4	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.5	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0008147	structural constituent of bone(GO:0008147)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.3	GO:0004549	tRNA-specific ribonuclease activity(GO:0004549)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.2	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0034739	histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.1	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.5	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.2	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.5	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.1	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.2	GO:0003996	acyl-CoA ligase activity(GO:0003996)
0.0	0.1	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.3	GO:0032452	histone demethylase activity(GO:0032452)
0.0	0.3	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.3	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.0	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0015272	ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.3	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.2	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:1990381	ubiquitin-specific protease binding(GO:1990381)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.2	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.2	GO:0016493	C-C chemokine receptor activity(GO:0016493)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.2	GO:0004861	cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0	0.8	GO:0070491	repressing transcription factor binding(GO:0070491)
0.0	0.0	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.0	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.1	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.4	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.0	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.7	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	0.0	GO:0019212	phosphatase inhibitor activity(GO:0019212)
0.0	0.8	GO:0019003	GDP binding(GO:0019003)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.6	GO:0035064	methylated histone binding(GO:0035064)
0.0	0.1	GO:0030250	cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.2	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451)
0.0	1.1	GO:0042826	histone deacetylase binding(GO:0042826)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.1	GO:0030169	low-density lipoprotein particle binding(GO:0030169)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.1	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.3	GO:0016701	oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701)
0.0	0.1	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.1	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.0	GO:0004385	guanylate kinase activity(GO:0004385)
0.0	0.1	GO:0008486	diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.4	GO:0033613	activating transcription factor binding(GO:0033613)
0.0	0.0	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0016668	oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668)
0.0	0.3	GO:0005487	nucleocytoplasmic transporter activity(GO:0005487)
0.0	0.7	GO:0008013	beta-catenin binding(GO:0008013)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.2	GO:0017091	AU-rich element binding(GO:0017091)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.2	GO:0031683	G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0017154	semaphorin receptor activity(GO:0017154)
0.0	0.0	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.0	GO:0019958	C-X-C chemokine binding(GO:0019958)
0.0	1.0	GO:0030165	PDZ domain binding(GO:0030165)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.0	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.1	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.1	0.2	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.3	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.6	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.8	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0	0.7	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.5	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.2	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.0	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.3	PID CD40 PATHWAY	CD40/CD40L signaling
0.0	0.7	PID ARF6 TRAFFICKING PATHWAY	Arf6 trafficking events
0.0	0.4	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.3	PID EPHB FWD PATHWAY	EPHB forward signaling
0.0	0.1	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.7	PID HDAC CLASSI PATHWAY	Signaling events mediated by HDAC Class I
0.0	0.7	PID E2F PATHWAY	E2F transcription factor network
0.0	0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	0.0	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.4	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.6	PID NOTCH PATHWAY	Notch signaling pathway
0.0	0.4	PID AP1 PATHWAY	AP-1 transcription factor network
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.5	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.3	PID ATF2 PATHWAY	ATF-2 transcription factor network
0.0	0.4	PID PLK1 PATHWAY	PLK1 signaling events
0.0	0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.3	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.2	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.1	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID RHOA PATHWAY	RhoA signaling pathway
0.0	0.1	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.2	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.1	0.6	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	0.8	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	0.5	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	0.4	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.1	0.7	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.5	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.4	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.8	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.4	REACTOME SIGNALING BY NOTCH4	Genes involved in Signaling by NOTCH4
0.0	0.4	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.4	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.4	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.4	REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS	Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.6	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER	Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0	0.0	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.4	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0	0.2	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.2	REACTOME OPSINS	Genes involved in Opsins
0.0	0.3	REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION	Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0	0.0	REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN	Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein
0.0	0.8	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME CHONDROITIN SULFATE DERMATAN SULFATE METABOLISM	Genes involved in Chondroitin sulfate/dermatan sulfate metabolism
0.0	0.1	REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS	Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.4	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	0.4	REACTOME MEIOTIC RECOMBINATION	Genes involved in Meiotic Recombination
0.0	0.0	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.2	REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS	Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0	0.1	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.2	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.2	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.3	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.2	REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B	Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0	0.0	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.3	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.2	REACTOME GAP JUNCTION TRAFFICKING	Genes involved in Gap junction trafficking
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME MICRORNA MIRNA BIOGENESIS	Genes involved in MicroRNA (miRNA) Biogenesis
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.3	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.0	REACTOME TRAF6 MEDIATED NFKB ACTIVATION	Genes involved in TRAF6 mediated NF-kB activation
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.3	REACTOME MEIOSIS	Genes involved in Meiosis
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex

Results for Pbx1_Pbx3

Z-value: 2.64

Motif logo

Transcription factors associated with Pbx1_Pbx3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Pbx1_Pbx3 motif across conditions

Conditions sorted by the z-value of the Pbx1_Pbx3 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pbx1_Pbx3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: