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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Pou2f2_Pou3f1

Z-value: 2.68

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Transcription factors associated with Pou2f2_Pou3f1

Gene Symbol	Gene ID	Gene Info
Pou2f2 Ensembl NCBI MGI UniProt	ENSMUSG00000008496.12	POU domain, class 2, transcription factor 2
Pou3f1 Ensembl NCBI MGI UniProt	ENSMUSG00000090125.2	POU domain, class 3, transcription factor 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_25120549_25120733	Pou2f2	217	0.890170	0.90	1.3e-02	Click!
chr7_25197796_25197968	Pou2f2	18156	0.076202	0.78	6.9e-02	Click!
chr7_25187772_25187940	Pou2f2	8130	0.093934	-0.67	1.5e-01	Click!
chr7_25133196_25133360	Pou2f2	766	0.508775	-0.30	5.6e-01	Click!
chr7_25129649_25129800	Pou2f2	2753	0.164735	-0.30	5.6e-01	Click!
chr4_124646730_124646881	Pou3f1	10002	0.118702	0.67	1.5e-01	Click!
chr4_124630137_124630316	Pou3f1	26581	0.108354	0.55	2.6e-01	Click!
chr4_124630436_124630602	Pou3f1	26288	0.108655	0.54	2.7e-01	Click!
chr4_124634694_124634849	Pou3f1	22036	0.112116	0.43	3.9e-01	Click!

Activity of the Pou2f2_Pou3f1 motif across conditions

Conditions sorted by the z-value of the Pou2f2_Pou3f1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr5_109557797_109558252	8.03	Crlf2	cytokine receptor-like factor 2	912	0.5
chr5_109558445_109558806	4.80	Crlf2	cytokine receptor-like factor 2	311	0.86
chr12_3236109_3236269	4.78	Rab10os	RAB10, member RAS oncogene family, opposite strand	274	0.89
chr1_189006324_189006498	3.67	Kctd3	potassium channel tetramerisation domain containing 3	1417	0.48
chr18_34864196_34864456	2.98	Egr1	early growth response 1	3119	0.18
chr13_23683913_23684244	2.71	H2bc4	H2B clustered histone 4	121	0.45
chr12_8003138_8004354	2.40	Apob	apolipoprotein B	8613	0.24
chr1_191924602_191924813	2.39	1700034H15Rik	RIKEN cDNA 1700034H15 gene	17180	0.13
chr15_95796824_95796987	2.21	Ano6	anoctamin 6	3817	0.14
chr11_58954509_58954669	2.20	H2bu1-ps	H2B.U histone 1, pseudogene	77	0.34
chr13_107616531_107616706	2.08	Gm32090	predicted gene, 32090	3769	0.28
chr6_136518661_136518819	2.02	Atf7ip	activating transcription factor 7 interacting protein	62	0.78
chr11_103102697_103103091	2.00	Acbd4	acyl-Coenzyme A binding domain containing 4	127	0.92
chr13_23746567_23746739	1.93	H2bc3	H2B clustered histone 3	81	0.52
chr14_67715796_67716014	1.84	Kctd9	potassium channel tetramerisation domain containing 9	32	0.52
chr2_109917459_109917628	1.83	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	104	0.97
chrX_7878095_7878259	1.80	Pim2	proviral integration site 2	85	0.92
chr2_158228733_158228893	1.80	D630003M21Rik	RIKEN cDNA D630003M21 gene	409	0.79
chr6_67037310_67037615	1.78	Gadd45a	growth arrest and DNA-damage-inducible 45 alpha	5	0.93
chr8_79392797_79393002	1.76	Smad1	SMAD family member 1	6619	0.19
chr9_102639370_102639523	1.74	Anapc13	anaphase promoting complex subunit 13	10934	0.13
chr3_122073686_122073843	1.72	Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	690	0.69
chr10_116287055_116287225	1.68	Gm47625	predicted gene, 47625	2591	0.27
chr10_79984935_79985317	1.67	Gm26243	predicted gene, 26243	380	0.56
chr16_30776361_30776512	1.66	Gm49754	predicted gene, 49754	16819	0.18
chr13_62880235_62880431	1.65	Fbp1	fructose bisphosphatase 1	7575	0.14
chr11_63093700_63093851	1.65	Tekt3	tektin 3	32121	0.15
chr6_145355079_145355230	1.64	Gm23498	predicted gene, 23498	11704	0.13
chr17_35164874_35165221	1.64	Gm17705	predicted gene, 17705	72	0.57
chr1_83959916_83960067	1.63	Gm24555	predicted gene, 24555	38073	0.17
chr7_27167002_27167378	1.61	Egln2	egl-9 family hypoxia-inducible factor 2	388	0.65
chr11_115641190_115641341	1.54	Slc25a19	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19	12970	0.09
chr7_73478544_73478710	1.52	Chd2	chromodomain helicase DNA binding protein 2	201	0.91
chr12_82225847_82226035	1.48	Sipa1l1	signal-induced proliferation-associated 1 like 1	30644	0.19
chr10_17549353_17549511	1.47	Gm47770	predicted gene, 47770	22518	0.17
chr10_79908872_79909048	1.46	Med16	mediator complex subunit 16	37	0.71
chr10_43927870_43928038	1.45	Rtn4ip1	reticulon 4 interacting protein 1	6919	0.19
chr19_55065799_55065977	1.44	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	33563	0.17
chr2_91109349_91109508	1.41	Mybpc3	myosin binding protein C, cardiac	8716	0.11
chr3_96220833_96221176	1.41	H2bc21	H2B clustered histone 21	115	0.42
chr15_37518986_37519177	1.40	Gm3267	predicted gene 3267	26325	0.14
chr10_28649859_28650024	1.40	Themis	thymocyte selection associated	18419	0.24
chr19_46484470_46484829	1.38	Sufu	SUFU negative regulator of hedgehog signaling	1552	0.33
chr11_101483861_101484050	1.37	Gm11625	predicted gene 11625	7729	0.08
chr18_53136034_53136196	1.36	Snx2	sorting nexin 2	40201	0.18
chr9_35050174_35050386	1.32	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	5514	0.2
chr17_35165511_35165752	1.30	Gm17705	predicted gene, 17705	512	0.34
chr1_174742197_174742666	1.29	Fmn2	formin 2	28105	0.24
chr7_134709304_134709497	1.28	Dock1	dedicator of cytokinesis 1	38278	0.18
chr1_118459451_118459613	1.27	Clasp1	CLIP associating protein 1	56	0.63
chr3_96269525_96269702	1.27	Gm42743	predicted gene 42743	108	0.48
chr11_35970865_35971211	1.26	Wwc1	WW, C2 and coiled-coil domain containing 1	9489	0.23
chr18_69591870_69592031	1.26	Tcf4	transcription factor 4	1038	0.64
chr9_102502360_102502529	1.23	Ky	kyphoscoliosis peptidase	3306	0.18
chr4_139964484_139964679	1.22	Mir2139	microRNA 2139	3039	0.2
chr12_71430131_71430651	1.19	1700083H02Rik	RIKEN cDNA 1700083H02 gene	46183	0.12
chr3_87164183_87164365	1.14	Gm37855	predicted gene, 37855	6581	0.17
chr4_53412087_53412238	1.14	Gm12496	predicted gene 12496	8132	0.22
chr4_57298104_57298290	1.13	Gm12536	predicted gene 12536	1899	0.29
chr10_23712810_23712979	1.13	Snora33	small nucleolar RNA, H/ACA box 33	72581	0.07
chr5_73360002_73360284	1.12	Ociad2	OCIA domain containing 2	19115	0.1
chr10_43244698_43244863	1.11	Pdss2	prenyl (solanesyl) diphosphate synthase, subunit 2	23044	0.16
chr3_96497489_96497655	1.11	Gm22614	predicted gene, 22614	8843	0.07
chr10_68735798_68735949	1.11	Tmem26	transmembrane protein 26	12049	0.25
chr17_29437327_29437486	1.10	Gm36486	predicted gene, 36486	42	0.96
chr17_86616279_86616430	1.10	Gm18832	predicted gene, 18832	69142	0.1
chrX_12089989_12090141	1.09	Bcor	BCL6 interacting corepressor	9512	0.27
chr2_103566159_103566321	1.09	Abtb2	ankyrin repeat and BTB (POZ) domain containing 2	70	0.97
chr3_69186136_69186307	1.09	Arl14	ADP-ribosylation factor-like 14	36198	0.12
chr18_61384223_61384382	1.07	Gm25301	predicted gene, 25301	13511	0.13
chr9_63698782_63698955	1.06	Smad3	SMAD family member 3	13101	0.22
chr2_63802996_63803147	1.06	Fign	fidgetin	294917	0.01
chr16_94632045_94632207	1.06	Gm15971	predicted gene 15971	11749	0.2
chr2_154609281_154609723	1.05	Zfp341	zinc finger protein 341	3795	0.12
chr12_52603467_52603629	1.05	Gm24859	predicted gene, 24859	240	0.8
chr4_142024660_142024842	1.04	4930455G09Rik	RIKEN cDNA 4930455G09 gene	6853	0.13
chr4_104211674_104212013	1.04	Dab1	disabled 1	155270	0.04
chr8_3221074_3221253	1.04	Insr	insulin receptor	28446	0.16
chr2_114788365_114788533	1.04	Gm13974	predicted gene 13974	65644	0.12
chr8_68880349_68880614	1.04	Lpl	lipoprotein lipase	10	0.98
chr11_43385156_43385341	1.03	Gm12148	predicted gene 12148	234	0.91
chr15_67469080_67469242	1.03	1700012I11Rik	RIKEN cDNA 1700012I11 gene	242392	0.02
chr13_21721884_21722046	1.02	H2bc14	H2B clustered histone 14	79	0.55
chr4_132794847_132795000	1.01	Themis2	thymocyte selection associated family member 2	1464	0.27
chr3_79378110_79378408	1.01	Gm17359	predicted gene, 17359	32880	0.17
chr9_123851204_123851402	1.00	Fyco1	FYVE and coiled-coil domain containing 1	358	0.82
chr1_171503359_171503541	1.00	Alyref2	Aly/REF export factor 2	28	0.75
chr9_122395930_122396300	0.99	A730085K08Rik	RIKEN cDNA A730085K08 gene	2686	0.2
chr12_76404035_76404198	0.98	Hspa2	heat shock protein 2	60	0.59
chr4_132270340_132270505	0.97	Rnu11	U11 small nuclear RNA	209	0.61
chr9_64774970_64775135	0.96	Dennd4a	DENN/MADD domain containing 4A	36288	0.13
chr6_136803797_136803969	0.96	H4f16	H4 histone 16	532	0.46
chr2_60864682_60865120	0.96	Rbms1	RNA binding motif, single stranded interacting protein 1	16537	0.26
chr2_178687049_178687253	0.95	Cdh26	cadherin-like 26	226521	0.02
chrX_11630744_11630906	0.95	Gm14515	predicted gene 14515	29471	0.2
chr5_147055875_147056177	0.95	Lnx2	ligand of numb-protein X 2	20560	0.15
chr16_33745461_33745732	0.95	Heg1	heart development protein with EGF-like domains 1	7560	0.2
chr2_173147902_173148417	0.94	Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	4889	0.18
chr3_98254262_98254424	0.93	Gm42821	predicted gene 42821	5744	0.16
chr6_38827530_38827757	0.93	Hipk2	homeodomain interacting protein kinase 2	9297	0.23
chr5_134330248_134330413	0.93	Mir3965	microRNA 3965	3876	0.16
chr8_125559051_125559202	0.93	Sipa1l2	signal-induced proliferation-associated 1 like 2	10577	0.23
chr2_5035353_5035529	0.92	Optn	optineurin	462	0.73
chr12_80947275_80947910	0.92	Srsf5	serine and arginine-rich splicing factor 5	1216	0.34
chr9_21936861_21937033	0.91	Plppr2	phospholipid phosphatase related 2	86	0.93
chr4_133569782_133569942	0.91	Gpatch3	G patch domain containing 3	4883	0.11
chr1_134221184_134221335	0.90	Adora1	adenosine A1 receptor	13319	0.13
chr5_145873496_145873886	0.90	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	3000	0.22
chr2_48441753_48441904	0.90	Gm13481	predicted gene 13481	15417	0.23
chr7_134022581_134022762	0.89	Adam12	a disintegrin and metallopeptidase domain 12 (meltrin alpha)	61406	0.12
chr5_100044741_100044892	0.89	Enoph1	enolase-phosphatase 1	4748	0.15
chr5_75320369_75320658	0.88	Gm18345	predicted gene, 18345	21930	0.17
chr6_128518176_128518418	0.88	Pzp	PZP, alpha-2-macroglobulin like	8406	0.09
chr11_96822735_96822898	0.87	Nfe2l1	nuclear factor, erythroid derived 2,-like 1	91	0.94
chr3_11357506_11357684	0.87	Gm22547	predicted gene, 22547	203258	0.03
chr12_21321297_21321467	0.87	Iah1	isoamyl acetate-hydrolyzing esterase 1 homolog	4946	0.13
chr3_19962880_19963390	0.86	Cp	ceruloplasmin	5851	0.19
chr9_124425147_124425308	0.85	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	1073	0.46
chr14_60655077_60655501	0.85	Spata13	spermatogenesis associated 13	20534	0.21
chr3_122235922_122236082	0.85	Gm22903	predicted gene, 22903	3366	0.12
chr8_122062883_122063072	0.84	Banp	BTG3 associated nuclear protein	62130	0.09
chr1_74401050_74401201	0.84	Mir26b	microRNA 26b	6815	0.11
chr7_141221710_141221874	0.83	Mir210	microRNA 210	299	0.74
chr4_105460170_105460436	0.83	Gm12723	predicted gene 12723	50929	0.16
chr9_58275190_58275612	0.82	Stoml1	stomatin-like 1	15174	0.13
chr16_33828590_33828758	0.82	Itgb5	integrin beta 5	991	0.5
chr2_155382110_155382266	0.82	Trp53inp2	transformation related protein 53 inducible nuclear protein 2	14	0.97
chr2_129338251_129338402	0.81	Gm25703	predicted gene, 25703	22847	0.09
chr18_4980453_4980617	0.81	Svil	supervillin	13278	0.29
chr11_90019278_90019441	0.81	Tmem100	transmembrane protein 100	10989	0.22
chr7_28372870_28373038	0.81	Plekhg2	pleckstrin homology domain containing, family G (with RhoGef domain) member 2	355	0.69
chr15_95887268_95887746	0.80	Gm25070	predicted gene, 25070	7690	0.19
chr11_16920982_16921140	0.80	Egfr	epidermal growth factor receptor	15876	0.16
chr10_46108907_46109077	0.79	Gm35430	predicted gene, 35430	119647	0.06
chr7_4812669_4813000	0.79	Ube2s	ubiquitin-conjugating enzyme E2S	244	0.81
chr4_118499414_118499578	0.79	Gm12859	predicted gene 12859	1854	0.2
chr16_35888329_35888480	0.79	Gm41467	predicted gene, 41467	3010	0.15
chr13_93619794_93619945	0.79	Gm15622	predicted gene 15622	5513	0.18
chr13_23571200_23571368	0.78	H2ac8	H2A clustered histone 8	64	0.51
chr4_120599080_120599244	0.78	Gm8439	predicted gene 8439	10416	0.14
chr17_10408924_10409260	0.78	A230009B12Rik	RIKEN cDNA A230009B12 gene	47124	0.15
chr10_125490636_125490927	0.77	Gm9102	predicted gene 9102	21750	0.25
chr9_51274775_51274960	0.76	2010007H06Rik	RIKEN cDNA 2010007H06 gene	3646	0.19
chr1_135258531_135258692	0.76	Elf3	E74-like factor 3	43	0.96
chr7_19572974_19573173	0.76	Gemin7	gem nuclear organelle associated protein 7	16	0.95
chr3_88149158_88149546	0.75	Mef2d	myocyte enhancer factor 2D	6778	0.11
chr16_3743869_3744203	0.75	Zfp263	zinc finger protein 263	57	0.96
chr5_65096928_65097079	0.74	Tmem156	transmembrane protein 156	4871	0.18
chr19_36731141_36731447	0.74	Ppp1r3c	protein phosphatase 1, regulatory subunit 3C	5359	0.23
chr2_26100418_26100578	0.73	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing	8321	0.14
chr2_146444142_146444488	0.73	Ralgapa2	Ral GTPase activating protein, alpha subunit 2 (catalytic)	2977	0.36
chrX_97377194_97377367	0.72	Eda2r	ectodysplasin A2 receptor	64	0.99
chr7_46029960_46030118	0.72	Abcc6	ATP-binding cassette, sub-family C (CFTR/MRP), member 6	263	0.86
chrX_10714805_10714993	0.72	Mid1ip1	Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))	114	0.96
chr8_103203752_103204163	0.72	Gm45391	predicted gene 45391	59011	0.14
chr2_173162056_173162207	0.72	Pck1	phosphoenolpyruvate carboxykinase 1, cytosolic	9049	0.17
chr19_30158286_30158444	0.72	Rpl31-ps20	ribosomal protein L31, pseudogene 20	2255	0.3
chr10_63158291_63158452	0.71	Mypn	myopalladin	35687	0.1
chr13_22035648_22035811	0.71	H2bc12	H2B clustered histone 12	141	0.46
chr4_149780302_149780453	0.71	Gm13073	predicted gene 13073	337	0.77
chr17_24355260_24355582	0.70	Abca3	ATP-binding cassette, sub-family A (ABC1), member 3	3319	0.12
chr5_87091073_87091224	0.70	Ugt2b36	UDP glucuronosyltransferase 2 family, polypeptide B36	9	0.96
chr2_25180576_25180750	0.70	Nrarp	Notch-regulated ankyrin repeat protein	95	0.9
chr8_11557968_11558143	0.70	Ing1	inhibitor of growth family, member 1	141	0.94
chr6_91104887_91105054	0.69	Nup210	nucleoporin 210	6348	0.17
chr2_24048425_24048585	0.69	Hnmt	histamine N-methyltransferase	361	0.89
chr11_100839662_100839847	0.69	Stat5b	signal transducer and activator of transcription 5B	10784	0.13
chr12_25092894_25093391	0.69	Id2	inhibitor of DNA binding 2	2945	0.22
chr6_145326227_145326383	0.68	Gm15707	predicted gene 15707	9697	0.12
chr4_97776996_97777177	0.68	Nfia	nuclear factor I/A	522	0.65
chr10_80930764_80930916	0.68	Gadd45b	growth arrest and DNA-damage-inducible 45 beta	28	0.95
chr8_82678823_82678982	0.67	Gm9655	predicted gene 9655	68714	0.11
chr5_146007397_146007568	0.67	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	2116	0.22
chr17_24139636_24139851	0.67	Pdpk1	3-phosphoinositide dependent protein kinase 1	1064	0.31
chr6_124730275_124730440	0.67	Ptpn6	protein tyrosine phosphatase, non-receptor type 6	1649	0.12
chr10_87895472_87895642	0.66	Igf1os	insulin-like growth factor 1, opposite strand	32176	0.15
chr19_20601861_20602027	0.66	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	17	0.98
chr3_14687354_14687539	0.66	Gm5843	predicted gene 5843	34970	0.13
chr3_145766447_145766648	0.66	Ddah1	dimethylarginine dimethylaminohydrolase 1	5799	0.22
chr10_68541223_68541548	0.66	Cabcoco1	ciliary associated calcium binding coiled-coil 1	511	0.83
chr7_45017710_45017888	0.65	Rras	related RAS viral (r-ras) oncogene	162	0.82
chr15_80799146_80799297	0.65	Tnrc6b	trinucleotide repeat containing 6b	506	0.82
chr15_82146982_82147172	0.65	Srebf2	sterol regulatory element binding factor 2	104	0.94
chr4_154964009_154964172	0.65	Pank4	pantothenate kinase 4	33	0.95
chr7_19876833_19877030	0.65	Gm44659	predicted gene 44659	5493	0.08
chr15_5195037_5195202	0.65	Ttc33	tetratricopeptide repeat domain 33	7765	0.13
chr3_27863421_27863589	0.65	Gm26040	predicted gene, 26040	4608	0.27
chr13_95783032_95783205	0.65	Iqgap2	IQ motif containing GTPase activating protein 2	18721	0.18
chr16_77434703_77434862	0.65	9430053O09Rik	RIKEN cDNA 9430053O09 gene	12962	0.11
chr8_11305954_11306113	0.64	Col4a1	collagen, type IV, alpha 1	6656	0.17
chr6_57544936_57545297	0.64	Ppm1k	protein phosphatase 1K (PP2C domain containing)	9648	0.15
chr10_117708756_117709505	0.64	Mdm2	transformed mouse 3T3 cell double minute 2	892	0.51
chr17_47588648_47588815	0.63	Ccnd3	cyclin D3	4705	0.12
chr7_100937600_100937760	0.63	Arhgef17	Rho guanine nucleotide exchange factor (GEF) 17	5573	0.15
chr5_135106619_135106914	0.63	Mlxipl	MLX interacting protein-like	125	0.92
chr7_75470307_75470471	0.62	Gm44834	predicted gene 44834	11610	0.16
chr5_125180096_125180482	0.62	Ncor2	nuclear receptor co-repressor 2	1070	0.57
chr12_52604765_52604949	0.62	Gm23296	predicted gene, 23296	266	0.81
chr15_67222145_67222401	0.61	1700012I11Rik	RIKEN cDNA 1700012I11 gene	4496	0.3
chr14_64850321_64850478	0.61	Gm37183	predicted gene, 37183	11140	0.16

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f2_Pou3f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.8	8.4	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.4	1.8	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.3	2.2	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.3	2.3	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.3	0.8	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.2	0.5	GO:1900211	mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.2	0.9	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.2	0.7	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.2	1.2	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.2	0.6	GO:0072223	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.2	0.6	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2	0.7	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.2	0.7	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.2	0.5	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2	0.6	GO:0009757	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.1	0.4	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.1	0.6	GO:0015822	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.1	0.6	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.1	0.6	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.1	0.4	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1	0.1	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.1	0.4	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.9	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1	0.5	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.1	0.5	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.1	0.3	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.3	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.1	0.3	GO:0009826	unidimensional cell growth(GO:0009826)
0.1	0.5	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.1	0.7	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.3	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.1	0.3	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1	0.2	GO:0060300	regulation of cytokine activity(GO:0060300)
0.1	0.3	GO:0060178	regulation of exocyst localization(GO:0060178)
0.1	0.2	GO:0060435	bronchiole development(GO:0060435)
0.1	0.3	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.1	0.3	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1	0.2	GO:0072718	response to cisplatin(GO:0072718)
0.1	0.1	GO:0070460	thyroid-stimulating hormone secretion(GO:0070460)
0.1	0.2	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1	0.9	GO:0060211	regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.1	0.9	GO:0060056	mammary gland involution(GO:0060056)
0.1	0.2	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.8	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.1	0.3	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.1	0.4	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.2	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.2	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1	0.7	GO:0002043	blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:0002043)
0.1	0.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.4	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.1	0.2	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1	0.2	GO:0036258	multivesicular body assembly(GO:0036258)
0.1	0.4	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.2	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.1	0.9	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1	0.7	GO:0015937	coenzyme A biosynthetic process(GO:0015937)
0.1	0.5	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.1	1.0	GO:0097237	cellular response to toxic substance(GO:0097237)
0.1	0.3	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1	0.3	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	0.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.3	GO:0032596	protein transport into membrane raft(GO:0032596)
0.1	0.2	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1	0.3	GO:2001012	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1	0.3	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.1	0.2	GO:0003166	bundle of His development(GO:0003166)
0.1	0.2	GO:0045472	response to ether(GO:0045472)
0.1	0.4	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.1	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.1	0.2	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.1	0.4	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.1	0.1	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.1	0.6	GO:0006527	arginine catabolic process(GO:0006527)
0.1	0.2	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.1	0.3	GO:0002051	osteoblast fate commitment(GO:0002051)
0.1	0.3	GO:0051045	negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.1	0.2	GO:0042732	D-xylose metabolic process(GO:0042732)
0.1	0.2	GO:0032898	neurotrophin production(GO:0032898)
0.1	0.2	GO:1902475	L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.1	0.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.3	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.1	0.3	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.1	0.5	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.1	0.2	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1	0.4	GO:1902306	negative regulation of sodium ion transmembrane transport(GO:1902306)
0.0	0.2	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.2	GO:0061072	iris morphogenesis(GO:0061072)
0.0	2.0	GO:0016239	positive regulation of macroautophagy(GO:0016239)
0.0	1.2	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.6	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:1903011	negative regulation of bone development(GO:1903011)
0.0	0.0	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.3	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.2	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.0	0.1	GO:0021986	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.2	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.1	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.0	0.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.2	GO:0021636	trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.0	0.5	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.0	GO:0014900	regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.0	0.1	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.5	GO:0043383	negative T cell selection(GO:0043383)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.1	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.1	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.3	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.3	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.2	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.3	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.0	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.2	GO:0010764	negative regulation of fibroblast migration(GO:0010764)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.2	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.9	GO:0035307	positive regulation of protein dephosphorylation(GO:0035307)
0.0	0.2	GO:0010310	regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0	0.1	GO:0060842	arterial endothelial cell differentiation(GO:0060842)
0.0	0.8	GO:0010508	positive regulation of autophagy(GO:0010508)
0.0	0.4	GO:0042573	retinoic acid metabolic process(GO:0042573)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.2	GO:0009115	xanthine catabolic process(GO:0009115)
0.0	0.1	GO:0000087	mitotic M phase(GO:0000087)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0046016	positive regulation of transcription by glucose(GO:0046016)
0.0	0.3	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.2	GO:0002076	osteoblast development(GO:0002076)
0.0	0.1	GO:1902896	terminal web assembly(GO:1902896)
0.0	1.1	GO:0045494	photoreceptor cell maintenance(GO:0045494)
0.0	0.1	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.1	GO:0009838	abscission(GO:0009838)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.3	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.2	GO:0045084	positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0	0.2	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.2	GO:0034244	negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.2	GO:0046473	phosphatidic acid biosynthetic process(GO:0006654) phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.2	GO:0090220	chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0	0.0	GO:2000416	regulation of eosinophil migration(GO:2000416)
0.0	0.0	GO:0048370	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.0	GO:0034384	high-density lipoprotein particle clearance(GO:0034384)
0.0	0.1	GO:0032687	negative regulation of interferon-alpha production(GO:0032687)
0.0	0.2	GO:0010826	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.0	GO:0061428	negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0	0.1	GO:0090611	ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0	0.1	GO:1904424	regulation of GTP binding(GO:1904424)
0.0	0.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.1	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.0	0.0	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.1	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.0	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.5	GO:0016180	snRNA processing(GO:0016180)
0.0	0.0	GO:0032661	regulation of interleukin-18 production(GO:0032661)
0.0	0.1	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.0	GO:0003164	His-Purkinje system development(GO:0003164)
0.0	0.2	GO:1904294	positive regulation of ERAD pathway(GO:1904294)
0.0	0.2	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.2	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:0015760	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0009093	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.6	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.3	GO:0034122	negative regulation of toll-like receptor signaling pathway(GO:0034122)
0.0	0.1	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.0	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.2	GO:0032060	bleb assembly(GO:0032060)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.0	GO:0010936	negative regulation of macrophage cytokine production(GO:0010936)
0.0	0.3	GO:0006353	DNA-templated transcription, termination(GO:0006353)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.0	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.1	GO:0031034	myosin filament assembly(GO:0031034)
0.0	0.7	GO:0006367	transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0	0.0	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0	0.0	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.5	GO:2001222	regulation of neuron migration(GO:2001222)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.0	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.1	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0021546	rhombomere development(GO:0021546)
0.0	0.0	GO:0061439	renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439)
0.0	0.0	GO:0071608	macrophage inflammatory protein-1 alpha production(GO:0071608)
0.0	0.0	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.2	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:0032485	Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.0	0.0	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.1	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999) neural plate regionalization(GO:0060897)
0.0	0.0	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.3	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.1	GO:2000665	interleukin-5 secretion(GO:0072603) interleukin-13 secretion(GO:0072611) regulation of interleukin-5 secretion(GO:2000662) regulation of interleukin-13 secretion(GO:2000665)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.0	GO:0010897	negative regulation of triglyceride catabolic process(GO:0010897)
0.0	0.2	GO:2000400	positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0	0.2	GO:0046339	diacylglycerol metabolic process(GO:0046339)
0.0	0.1	GO:0010990	regulation of SMAD protein complex assembly(GO:0010990)
0.0	0.0	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.0	0.1	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.3	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0	0.6	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.2	GO:0045723	positive regulation of fatty acid biosynthetic process(GO:0045723)
0.0	0.1	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.0	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.0	GO:1902430	negative regulation of beta-amyloid formation(GO:1902430)
0.0	0.0	GO:0002674	negative regulation of acute inflammatory response(GO:0002674)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.0	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.0	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.1	GO:0045063	T-helper 1 cell differentiation(GO:0045063)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.3	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0097051	establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0	0.1	GO:0043970	histone H3-K9 acetylation(GO:0043970)
0.0	0.6	GO:0072332	intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.0	0.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.1	GO:0010388	cullin deneddylation(GO:0010388)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:1901979	regulation of inward rectifier potassium channel activity(GO:1901979)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0006450	regulation of translational fidelity(GO:0006450)
0.0	0.2	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0048619	hindgut morphogenesis(GO:0007442) embryonic hindgut morphogenesis(GO:0048619)
0.0	0.0	GO:0002461	tolerance induction dependent upon immune response(GO:0002461)
0.0	0.0	GO:0051683	establishment of Golgi localization(GO:0051683)
0.0	0.2	GO:0006825	copper ion transport(GO:0006825)
0.0	0.0	GO:0098763	mitotic cell cycle phase(GO:0098763)
0.0	0.1	GO:0043653	mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0	0.0	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.0	GO:0061205	paramesonephric duct development(GO:0061205)
0.0	0.9	GO:1903749	positive regulation of establishment of protein localization to mitochondrion(GO:1903749)
0.0	0.1	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0015838	amino-acid betaine transport(GO:0015838)
0.0	0.0	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.1	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.6	GO:0045576	mast cell activation(GO:0045576)
0.0	0.0	GO:0002017	regulation of blood volume by renal aldosterone(GO:0002017)
0.0	0.2	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.0	0.0	GO:1904956	regulation of midbrain dopaminergic neuron differentiation(GO:1904956)
0.0	0.0	GO:1902093	positive regulation of sperm motility(GO:1902093)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0051031	tRNA transport(GO:0051031)
0.0	0.3	GO:0048873	homeostasis of number of cells within a tissue(GO:0048873)
0.0	0.3	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.1	GO:0035970	peptidyl-threonine dephosphorylation(GO:0035970)
0.0	0.0	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:0048539	bone marrow development(GO:0048539)
0.0	0.0	GO:0051573	negative regulation of histone H3-K9 methylation(GO:0051573)
0.0	0.0	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.2	GO:0032981	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0045974	negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0	0.1	GO:1901072	glucosamine-containing compound catabolic process(GO:1901072)
0.0	0.0	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.0	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.0	GO:0045196	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.0	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	0.4	GO:0097194	execution phase of apoptosis(GO:0097194)
0.0	0.0	GO:0001803	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0	0.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.0	GO:0060332	positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0	0.0	GO:0060235	lens induction in camera-type eye(GO:0060235)
0.0	0.1	GO:0048664	neuron fate determination(GO:0048664)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.0	GO:0009298	GDP-mannose biosynthetic process(GO:0009298)
0.0	0.1	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:0021554	optic nerve development(GO:0021554)
0.0	0.1	GO:0002585	positive regulation of antigen processing and presentation of peptide antigen(GO:0002585) positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591)
0.0	0.0	GO:0098910	regulation of atrial cardiac muscle cell action potential(GO:0098910)
0.0	0.0	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.0	GO:0097029	mature conventional dendritic cell differentiation(GO:0097029)
0.0	0.0	GO:0032713	negative regulation of interleukin-4 production(GO:0032713)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.0	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.1	GO:0042984	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0	0.0	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.1	GO:0048857	neural nucleus development(GO:0048857)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.0	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.0	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.0	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.0	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.1	GO:0006983	ER overload response(GO:0006983)
0.0	0.0	GO:0033058	directional locomotion(GO:0033058)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.2	0.6	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.6	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	1.1	GO:0042627	chylomicron(GO:0042627)
0.1	0.8	GO:0072687	meiotic spindle(GO:0072687)
0.1	0.2	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.1	0.5	GO:0000788	nuclear nucleosome(GO:0000788)
0.1	0.6	GO:0061700	GATOR2 complex(GO:0061700)
0.1	0.3	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	0.2	GO:1990462	omegasome(GO:1990462)
0.1	0.2	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.1	0.6	GO:0032797	SMN complex(GO:0032797)
0.1	0.2	GO:0032021	NELF complex(GO:0032021)
0.1	0.2	GO:0097513	myosin II filament(GO:0097513)
0.1	0.4	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0000235	astral microtubule(GO:0000235)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.3	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.5	GO:0098636	integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0	0.3	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.4	GO:0032039	integrator complex(GO:0032039)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	1.5	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	8.5	GO:0009897	external side of plasma membrane(GO:0009897)
0.0	0.2	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.2	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.3	GO:0031143	pseudopodium(GO:0031143)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0043020	NADPH oxidase complex(GO:0043020)
0.0	0.0	GO:0034365	discoidal high-density lipoprotein particle(GO:0034365)
0.0	0.4	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0	1.2	GO:0005776	autophagosome(GO:0005776)
0.0	0.8	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.2	GO:0017059	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0030670	phagocytic vesicle membrane(GO:0030670)
0.0	1.3	GO:0001750	photoreceptor outer segment(GO:0001750)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.4	GO:0005839	proteasome core complex(GO:0005839)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.5	GO:0008180	COP9 signalosome(GO:0008180)
0.0	0.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.0	0.4	GO:0005680	anaphase-promoting complex(GO:0005680)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.1	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.2	GO:0032433	filopodium tip(GO:0032433)
0.0	0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.3	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.1	GO:0090543	Flemming body(GO:0090543)
0.0	0.0	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.7	GO:0042734	presynaptic membrane(GO:0042734)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.6	GO:0032587	ruffle membrane(GO:0032587)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.2	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0002080	acrosomal membrane(GO:0002080)
0.0	0.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.0	GO:0005956	protein kinase CK2 complex(GO:0005956)
0.0	0.1	GO:0000407	pre-autophagosomal structure(GO:0000407)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.2	GO:0097610	cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0	0.2	GO:0046658	anchored component of plasma membrane(GO:0046658)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.3	GO:0030687	preribosome, large subunit precursor(GO:0030687)
0.0	0.1	GO:0000812	Swr1 complex(GO:0000812)
0.0	0.0	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.6	GO:0000118	histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2	1.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.2	0.7	GO:0043515	kinetochore binding(GO:0043515)
0.2	0.5	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.2	0.7	GO:0070878	primary miRNA binding(GO:0070878)
0.2	0.5	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.2	0.6	GO:0004594	pantothenate kinase activity(GO:0004594)
0.2	1.2	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1	0.7	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.1	0.5	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	0.6	GO:0015181	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.1	0.6	GO:0030274	LIM domain binding(GO:0030274)
0.1	1.6	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.1	0.3	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.1	0.3	GO:1990460	leptin receptor binding(GO:1990460)
0.1	0.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.6	GO:0035473	lipase binding(GO:0035473)
0.1	1.4	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.1	0.2	GO:0043426	MRF binding(GO:0043426)
0.1	0.7	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.1	0.8	GO:0042577	lipid phosphatase activity(GO:0042577)
0.1	0.2	GO:0070840	dynein complex binding(GO:0070840)
0.1	0.4	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.3	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.1	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.1	0.3	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.3	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.2	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0030984	kininogen binding(GO:0030984)
0.1	0.2	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1	0.2	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.1	0.8	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	0.2	GO:0015057	thrombin receptor activity(GO:0015057)
0.1	0.8	GO:0034185	apolipoprotein binding(GO:0034185)
0.1	0.3	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.2	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.1	0.2	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.1	0.3	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1	0.2	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.5	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.2	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.3	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.1	GO:0005502	11-cis retinal binding(GO:0005502)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	1.2	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	8.2	GO:0005125	cytokine activity(GO:0005125)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.6	GO:0051861	glycolipid binding(GO:0051861)
0.0	0.3	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.2	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.8	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.4	GO:0005247	voltage-gated chloride channel activity(GO:0005247)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.5	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.4	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.2	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.2	GO:0004854	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.1	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.2	GO:0043121	neurotrophin binding(GO:0043121)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.7	GO:0035035	histone acetyltransferase binding(GO:0035035)
0.0	0.1	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.4	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.2	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.2	GO:0000983	transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0	0.2	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.1	GO:0061133	endopeptidase activator activity(GO:0061133)
0.0	0.2	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.2	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	1.5	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.4	GO:0004298	threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0	0.4	GO:0031492	nucleosomal DNA binding(GO:0031492)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.2	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.0	GO:0019002	GMP binding(GO:0019002)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.1	GO:0003691	double-stranded telomeric DNA binding(GO:0003691)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0004305	ethanolamine kinase activity(GO:0004305)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.0	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.1	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.2	GO:0031210	phosphatidylcholine binding(GO:0031210)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.0	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.2	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.0	GO:0001226	RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.2	GO:0043422	protein kinase B binding(GO:0043422)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	1.9	GO:0003714	transcription corepressor activity(GO:0003714)
0.0	0.3	GO:0033558	protein deacetylase activity(GO:0033558)
0.0	0.2	GO:0016594	glycine binding(GO:0016594)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.1	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.0	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	1.5	GO:0042393	histone binding(GO:0042393)
0.0	0.3	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0031005	filamin binding(GO:0031005)
0.0	0.0	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.0	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.3	GO:0045182	translation regulator activity(GO:0045182)
0.0	0.1	GO:0004568	chitinase activity(GO:0004568)
0.0	0.2	GO:0001221	transcription cofactor binding(GO:0001221)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.7	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.2	GO:0019865	immunoglobulin binding(GO:0019865)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.0	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1	2.1	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.1	1.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	0.3	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0	1.9	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.6	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.6	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.4	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	1.0	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	1.1	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.0	0.5	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.5	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	0.1	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.8	PID RAS PATHWAY	Regulation of Ras family activation
0.0	1.2	PID AR PATHWAY	Coregulation of Androgen receptor activity
0.0	0.3	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	0.3	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.5	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.4	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.7	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.0	0.2	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway
0.0	0.2	ST G ALPHA S PATHWAY	G alpha s Pathway
0.0	0.1	PID CXCR4 PATHWAY	CXCR4-mediated signaling events
0.0	0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.3	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.6	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.0	0.1	SIG PIP3 SIGNALING IN CARDIAC MYOCTES	Genes related to PIP3 signaling in cardiac myocytes
0.0	0.2	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.1	PID EPO PATHWAY	EPO signaling pathway
0.0	0.0	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.5	SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES	Genes related to regulation of the actin cytoskeleton
0.0	0.1	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.0	0.3	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.2	PID NEPHRIN NEPH1 PATHWAY	Nephrin/Neph1 signaling in the kidney podocyte
0.0	0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases
0.0	0.4	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.0	0.5	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.0	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	0.3	PID IL4 2PATHWAY	IL4-mediated signaling events
0.0	0.2	PID MYC PATHWAY	C-MYC pathway
0.0	0.2	PID CDC42 PATHWAY	CDC42 signaling events
0.0	0.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.1	1.6	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.1	1.3	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1	0.5	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.1	0.6	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.1	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.1	1.0	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	0.7	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.1	1.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.1	0.7	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.5	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.3	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.1	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.0	0.2	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	1.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.3	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.8	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.9	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.1	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.3	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.7	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.5	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.4	REACTOME SIGNALING BY HIPPO	Genes involved in Signaling by Hippo
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.1	REACTOME ACTIVATION OF NF KAPPAB IN B CELLS	Genes involved in Activation of NF-kappaB in B Cells
0.0	0.5	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.7	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.2	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.0	0.4	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.6	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.2	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.5	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.0	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.5	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.2	REACTOME REGULATION OF KIT SIGNALING	Genes involved in Regulation of KIT signaling
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	1.1	REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION	Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.3	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.7	REACTOME METABOLISM OF NON CODING RNA	Genes involved in Metabolism of non-coding RNA
0.0	0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.1	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0	0.0	REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION	Genes involved in Pre-NOTCH Transcription and Translation
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.0	REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS	Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0	0.2	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.1	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.1	REACTOME BASIGIN INTERACTIONS	Genes involved in Basigin interactions

Results for Pou2f2_Pou3f1

Z-value: 2.68

Motif logo

Transcription factors associated with Pou2f2_Pou3f1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Pou2f2_Pou3f1 motif across conditions

Conditions sorted by the z-value of the Pou2f2_Pou3f1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f2_Pou3f1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: