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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Pou3f3

Z-value: 1.00

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Transcription factors associated with Pou3f3

Gene Symbol Gene ID Gene Info
Pou3f3
ENSMUSG00000045515.2 POU domain, class 3, transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_42699734_42699893Pou3f340450.1551670.853.0e-02Click!

Activity of the Pou3f3 motif across conditions

Conditions sorted by the z-value of the Pou3f3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_3046150_3046544 1.29 Gm44634
 predicted gene 44634
 9947
 0.2
chr3_51255928_51256079 1.10 Elf2
 E74-like factor 2
 4238
 0.15
chr10_89492629_89492900 1.03 Nr1h4
 nuclear receptor subfamily 1, group H, member 4
 13885
 0.21
chr3_97649987_97650151 1.01 Prkab2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
 8124
 0.13
chr13_43549369_43549520 0.91 Mcur1
 mitochondrial calcium uniporter regulator 1
 3324
 0.2
chr3_144109828_144110050 0.89 Gm34078
 predicted gene, 34078
 25815
 0.2
chr15_3470264_3470480 0.84 Ghr
 growth hormone receptor
 1272
 0.6
chr8_93183570_93183871 0.84 Gm45909
 predicted gene 45909
 7638
 0.14
chr16_37902225_37902391 0.74 Gpr156
 G protein-coupled receptor 156
 14188
 0.14
chr8_93164567_93164980 0.73 Ces1d
 carboxylesterase 1D
 5202
 0.15
chr8_93185812_93185963 0.72 Gm45909
 predicted gene 45909
 5471
 0.15
chr9_70446864_70447026 0.71 Rnf111
 ring finger 111
 6901
 0.16
chr15_36280810_36280963 0.70 Rnf19a
 ring finger protein 19A
 2212
 0.2
chr1_67181891_67182275 0.70 Cps1
 carbamoyl-phosphate synthetase 1
 59057
 0.11
chr1_67183580_67183935 0.68 Cps1
 carbamoyl-phosphate synthetase 1
 60731
 0.11
chr11_11931538_11931698 0.65 Grb10
 growth factor receptor bound protein 10
 6998
 0.19
chr8_93165222_93165456 0.65 Ces1d
 carboxylesterase 1D
 4636
 0.15
chr1_31097093_31097258 0.63 4931428L18Rik
 RIKEN cDNA 4931428L18 gene
 721
 0.62
chr17_64676171_64676533 0.62 Man2a1
 mannosidase 2, alpha 1
 37068
 0.18
chr1_71723212_71723548 0.59 Gm5256
 predicted gene 5256
 8456
 0.19
chr2_58773911_58774203 0.57 Upp2
 uridine phosphorylase 2
 8732
 0.21
chr4_150866491_150867250 0.57 Errfi1
 ERBB receptor feedback inhibitor 1
 11797
 0.13
chr12_16633839_16633990 0.56 Lpin1
 lipin 1
 13052
 0.17
chr2_134947281_134947437 0.55 Gm14036
 predicted gene 14036
 143410
 0.04
chr6_13654409_13654594 0.52 Bmt2
 base methyltransferase of 25S rRNA 2
 23437
 0.21
chr11_31675803_31675997 0.52 Bod1
 biorientation of chromosomes in cell division 1
 4015
 0.27
chr1_106630171_106630322 0.51 Gm37053
 predicted gene, 37053
 23376
 0.19
chr5_8842744_8842895 0.49 Abcb1b
 ATP-binding cassette, sub-family B (MDR/TAP), member 1B
 2458
 0.24
chr11_5347339_5347533 0.48 Znrf3
 zinc and ring finger 3
 34304
 0.15
chr2_67977965_67978321 0.48 Gm37964
 predicted gene, 37964
 79547
 0.1
chr10_76531927_76532170 0.48 Lss
 lanosterol synthase
 366
 0.79
chr17_13821264_13821648 0.48 Afdn
 afadin, adherens junction formation factor
 29506
 0.14
chr6_6206187_6206411 0.47 Slc25a13
 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
 10819
 0.23
chr8_93258499_93258650 0.47 Ces1f
 carboxylesterase 1F
 165
 0.94
chr6_138152720_138152908 0.47 Mgst1
 microsomal glutathione S-transferase 1
 9960
 0.28
chr1_13670589_13670740 0.47 Xkr9
 X-linked Kx blood group related 9
 1893
 0.32
chr11_103696519_103696670 0.47 Gosr2
 golgi SNAP receptor complex member 2
 1100
 0.31
chr4_35533897_35534048 0.47 Gm12365
 predicted gene 12365
 97758
 0.08
chr8_101350931_101351097 0.46 Gm22223
 predicted gene, 22223
 188694
 0.03
chr4_108085090_108085394 0.45 Mir6397
 microRNA 6397
 2115
 0.24
chr16_43286493_43286831 0.45 Gm37946
 predicted gene, 37946
 21619
 0.16
chr5_147726852_147727014 0.45 Flt1
 FMS-like tyrosine kinase 1
 922
 0.61
chr6_95652369_95652586 0.44 Suclg2
 succinate-Coenzyme A ligase, GDP-forming, beta subunit
 4991
 0.35
chr3_60097884_60098081 0.44 Sucnr1
 succinate receptor 1
 16080
 0.18
chr1_162892140_162892544 0.43 Fmo2
 flavin containing monooxygenase 2
 5827
 0.19
chr2_112284742_112285127 0.42 Slc12a6
 solute carrier family 12, member 6
 357
 0.81
chr16_42910018_42910191 0.42 Gm19522
 predicted gene, 19522
 1961
 0.29
chr19_17506726_17506895 0.42 Rfk
 riboflavin kinase
 109373
 0.07
chr16_56714341_56714503 0.42 Tfg
 Trk-fused gene
 1446
 0.47
chr3_151831850_151832001 0.41 Ptgfr
 prostaglandin F receptor
 2230
 0.27
chr19_40512528_40512992 0.39 Sorbs1
 sorbin and SH3 domain containing 1
 913
 0.57
chr9_95558523_95558904 0.39 Paqr9
 progestin and adipoQ receptor family member IX
 944
 0.41
chr13_102570134_102570306 0.39 Gm29927
 predicted gene, 29927
 20065
 0.22
chr5_147747897_147748048 0.38 Gm43156
 predicted gene 43156
 2456
 0.3
chr5_17964323_17964474 0.38 Gnat3
 guanine nucleotide binding protein, alpha transducing 3
 1849
 0.49
chr19_58049317_58049501 0.36 Mir5623
 microRNA 5623
 1758
 0.46
chr17_13825284_13825458 0.36 Afdn
 afadin, adherens junction formation factor
 25591
 0.15
chr8_20561636_20561787 0.36 Gm21182
 predicted gene, 21182
 4225
 0.2
chr8_25750286_25750467 0.35 Ddhd2
 DDHD domain containing 2
 526
 0.61
chr6_43643507_43643672 0.35 Tpk1
 thiamine pyrophosphokinase
 17623
 0.25
chr12_4455371_4455763 0.34 Ncoa1
 nuclear receptor coactivator 1
 21615
 0.16
chr7_25422600_25422802 0.34 Gm20949
 predicted gene, 20949
 91
 0.93
chr7_26817080_26817232 0.34 Cyp2g1
 cytochrome P450, family 2, subfamily g, polypeptide 1
 861
 0.56
chr4_48225504_48225656 0.34 Mir1958
 microRNA 1958
 12365
 0.19
chr2_105949709_105950077 0.33 Gm22002
 predicted gene, 22002
 42864
 0.1
chr6_100858577_100858772 0.33 Ppp4r2
 protein phosphatase 4, regulatory subunit 2
 6097
 0.23
chr18_38370754_38370932 0.33 Gm4949
 predicted gene 4949
 10305
 0.12
chr11_54003633_54003801 0.33 Slc22a4
 solute carrier family 22 (organic cation transporter), member 4
 4247
 0.16
chr11_16780614_16780813 0.32 Egfr
 epidermal growth factor receptor
 28483
 0.16
chr13_7307728_7307879 0.31 Gm8725
 predicted gene 8725
 1
 0.99
chr5_90899182_90899382 0.31 Cxcl2
 chemokine (C-X-C motif) ligand 2
 4589
 0.13
chr17_26702508_26702992 0.30 Crebrf
 CREB3 regulatory factor
 12900
 0.14
chr3_60111256_60111413 0.30 Gm24382
 predicted gene, 24382
 16413
 0.19
chr10_4736776_4736976 0.30 Esr1
 estrogen receptor 1 (alpha)
 24225
 0.25
chr2_4999219_4999388 0.30 Mcm10
 minichromosome maintenance 10 replication initiation factor
 2255
 0.21
chr1_3515265_3515420 0.30 Gm37329
 predicted gene, 37329
 835
 0.6
chr2_147905769_147905939 0.29 Gm25516
 predicted gene, 25516
 30976
 0.2
chr3_118606217_118606485 0.29 Dpyd
 dihydropyrimidine dehydrogenase
 44165
 0.15
chr18_66004765_66005080 0.28 Lman1
 lectin, mannose-binding, 1
 2283
 0.22
chr6_24610468_24610637 0.28 Lmod2
 leiomodin 2 (cardiac)
 12790
 0.14
chr4_94555776_94555981 0.28 Caap1
 caspase activity and apoptosis inhibitor 1
 888
 0.53
chr8_20817807_20818117 0.28 Gm20946
 predicted gene, 20946
 10391
 0.15
chr2_160848002_160848255 0.28 Gm11447
 predicted gene 11447
 2515
 0.22
chr4_108096711_108097042 0.27 Podn
 podocan
 431
 0.78
chr19_12684439_12684625 0.27 Gm49772
 predicted gene, 49772
 2761
 0.13
chr3_116302483_116302634 0.27 Gm29151
 predicted gene 29151
 47545
 0.11
chr2_11427432_11427583 0.27 Gm13296
 predicted gene 13296
 7283
 0.12
chr4_97900129_97900314 0.27 Nfia
 nuclear factor I/A
 10812
 0.29
chr3_152478706_152478877 0.27 Ak5
 adenylate kinase 5
 276
 0.91
chrY_90810953_90811113 0.26 Gm47283
 predicted gene, 47283
 20582
 0.16
chr4_136145338_136145489 0.26 Id3
 inhibitor of DNA binding 3
 439
 0.76
chr2_152830017_152830168 0.26 Bcl2l1
 BCL2-like 1
 218
 0.9
chr17_35815959_35816154 0.26 Ier3
 immediate early response 3
 5628
 0.08
chr6_149010896_149011065 0.26 Dennd5b
 DENN/MADD domain containing 5B
 6208
 0.11
chr9_94017367_94017557 0.25 Gm5369
 predicted gene 5369
 122000
 0.06
chr11_111998446_111998808 0.25 Gm11679
 predicted gene 11679
 44951
 0.19
chr1_15616194_15616345 0.25 Gm37138
 predicted gene, 37138
 60020
 0.12
chr6_137754996_137755471 0.25 Dera
 deoxyribose-phosphate aldolase (putative)
 618
 0.77
chr2_17326719_17326870 0.25 Nebl
 nebulette
 34292
 0.22
chr5_96304997_96305161 0.24 Fras1
 Fraser extracellular matrix complex subunit 1
 68876
 0.11
chr5_25496952_25497103 0.24 Kmt2c
 lysine (K)-specific methyltransferase 2C
 1675
 0.26
chr9_49485368_49485519 0.24 Ttc12
 tetratricopeptide repeat domain 12
 772
 0.68
chr1_162815471_162815637 0.24 Fmo4
 flavin containing monooxygenase 4
 1582
 0.37
chr16_37874612_37874787 0.24 Lrrc58
 leucine rich repeat containing 58
 6310
 0.14
chr2_164823177_164823502 0.24 Zswim1
 zinc finger SWIM-type containing 1
 326
 0.72
chrX_170020041_170020212 0.24 Erdr1
 erythroid differentiation regulator 1
 9382
 0.18
chr5_124424178_124424509 0.24 Gm37415
 predicted gene, 37415
 354
 0.67
chr10_4618857_4619069 0.24 Esr1
 estrogen receptor 1 (alpha)
 6942
 0.24
chr6_144170659_144171019 0.23 Sox5
 SRY (sex determining region Y)-box 5
 33218
 0.23
chr9_96952383_96952534 0.23 Spsb4
 splA/ryanodine receptor domain and SOCS box containing 4
 19517
 0.15
chr17_53650070_53650394 0.23 Kat2b
 K(lysine) acetyltransferase 2B
 5535
 0.15
chr16_43247311_43247635 0.23 Zbtb20
 zinc finger and BTB domain containing 20
 189
 0.95
chr10_89450844_89451017 0.23 Gas2l3
 growth arrest-specific 2 like 3
 6963
 0.25
chr1_131287169_131287361 0.22 Ikbke
 inhibitor of kappaB kinase epsilon
 7659
 0.12
chr4_115411935_115412583 0.22 Cyp4a12b
 cytochrome P450, family 4, subfamily a, polypeptide 12B
 635
 0.62
chr2_164447965_164448116 0.22 Sdc4
 syndecan 4
 4153
 0.1
chr18_33352007_33352191 0.22 Gm5503
 predicted gene 5503
 32856
 0.21
chr4_55352435_55352713 0.22 Rad23b
 RAD23 homolog B, nucleotide excision repair protein
 2484
 0.24
chr6_149147053_149147326 0.22 Etfbkmt
 electron transfer flavoprotein beta subunit lysine methyltransferase
 5543
 0.14
chr17_80772516_80772751 0.22 Map4k3
 mitogen-activated protein kinase kinase kinase kinase 3
 44148
 0.15
chr8_20289022_20289260 0.21 6820431F20Rik
 RIKEN cDNA 6820431F20 gene
 5875
 0.25
chr3_105773852_105774003 0.21 Gm43329
 predicted gene 43329
 3730
 0.13
chr4_136246535_136246839 0.21 Tcea3
 transcription elongation factor A (SII), 3
 1042
 0.46
chr5_51537712_51537892 0.21 Ppargc1a
 peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
 16069
 0.16
chr9_95540268_95540439 0.21 Gm32281
 predicted gene, 32281
 14144
 0.13
chr9_62087393_62087544 0.21 Glce
 glucuronyl C5-epimerase
 16628
 0.19
chr4_57122143_57122466 0.21 Epb41l4b
 erythrocyte membrane protein band 4.1 like 4b
 2244
 0.35
chr5_87457817_87457968 0.21 Ugt2a2
 UDP glucuronosyltransferase 2 family, polypeptide A2
 24366
 0.1
chr16_58662034_58662449 0.21 Gm49701
 predicted gene, 49701
 6997
 0.13
chr1_71807937_71808302 0.21 Gm37217
 predicted gene, 37217
 38491
 0.15
chr5_90519183_90519413 0.20 Afm
 afamin
 349
 0.81
chr12_32768098_32768327 0.20 Nampt
 nicotinamide phosphoribosyltransferase
 51333
 0.12
chr6_24964522_24964682 0.20 Tmem229a
 transmembrane protein 229A
 8305
 0.22
chr3_97653684_97653893 0.20 Prkab2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
 4405
 0.15
chr8_127463314_127463465 0.20 Pard3
 par-3 family cell polarity regulator
 15643
 0.28
chr10_115386783_115386953 0.20 Zfc3h1
 zinc finger, C3H1-type containing
 1909
 0.24
chr1_67133525_67134193 0.20 Cps1
 carbamoyl-phosphate synthetase 1
 10833
 0.24
chr2_77173287_77173438 0.20 Ccdc141
 coiled-coil domain containing 141
 2726
 0.29
chr2_58782728_58782879 0.20 Upp2
 uridine phosphorylase 2
 17478
 0.19
chr3_144255924_144256075 0.20 Gm43446
 predicted gene 43446
 27812
 0.16
chr18_60243095_60243283 0.20 Gm5970
 predicted gene 5970
 22346
 0.13
chr9_66600725_66600966 0.19 Usp3
 ubiquitin specific peptidase 3
 7703
 0.2
chr5_86942001_86942153 0.19 Gm24121
 predicted gene, 24121
 13069
 0.09
chr1_170608002_170608165 0.19 Nos1ap
 nitric oxide synthase 1 (neuronal) adaptor protein
 18222
 0.17
chr2_109684188_109684342 0.19 Bdnf
 brain derived neurotrophic factor
 7233
 0.19
chr2_81270788_81270939 0.19 Gm23900
 predicted gene, 23900
 272479
 0.01
chrY_90794490_90794856 0.19 Gm47283
 predicted gene, 47283
 4222
 0.21
chr19_34868908_34869317 0.19 Pank1
 pantothenate kinase 1
 8737
 0.17
chr9_67845546_67845728 0.19 Vps13c
 vacuolar protein sorting 13C
 5225
 0.21
chr4_105179161_105179312 0.19 Plpp3
 phospholipid phosphatase 3
 21889
 0.24
chr1_182959595_182959833 0.19 Tlr5
 toll-like receptor 5
 4886
 0.22
chr6_140199181_140199332 0.19 Gm24174
 predicted gene, 24174
 32611
 0.16
chr11_119048222_119048411 0.19 Cbx8
 chromobox 8
 7347
 0.16
chr11_30773137_30773288 0.19 Psme4
 proteasome (prosome, macropain) activator subunit 4
 891
 0.53
chr6_72431165_72431316 0.18 Mat2a
 methionine adenosyltransferase II, alpha
 3751
 0.13
chrX_170022175_170022352 0.18 Erdr1
 erythroid differentiation regulator 1
 11519
 0.18
chr6_143513821_143514027 0.18 4930579D09Rik
 RIKEN cDNA 4930579D09 gene
 21584
 0.23
chr9_74326904_74327074 0.18 Gm24141
 predicted gene, 24141
 35621
 0.16
chr18_35499140_35499327 0.18 Sil1
 endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
 304
 0.64
chr5_137778433_137778610 0.18 Ppp1r35
 protein phosphatase 1, regulatory subunit 35
 328
 0.76
chr1_65156847_65157132 0.18 Idh1
 isocitrate dehydrogenase 1 (NADP+), soluble
 18575
 0.11
chr17_70661451_70661755 0.17 5031415H12Rik
 RIKEN cDNA 5031415H12 gene
 93979
 0.07
chr1_131990500_131990816 0.17 Slc45a3
 solute carrier family 45, member 3
 11694
 0.12
chr1_21299385_21299536 0.17 Gm4956
 predicted gene 4956
 1148
 0.32
chr8_77100242_77100465 0.17 Nr3c2
 nuclear receptor subfamily 3, group C, member 2
 27660
 0.19
chr5_90696399_90696550 0.17 Gm43090
 predicted gene 43090
 54051
 0.08
chr15_103307817_103307990 0.17 Gpr84
 G protein-coupled receptor 84
 2709
 0.14
chr7_119960819_119960970 0.17 Dnah3
 dynein, axonemal, heavy chain 3
 6948
 0.16
chr3_51917272_51917733 0.17 Gm10728
 predicted gene 10728
 8686
 0.13
chr3_106496243_106496679 0.17 Dennd2d
 DENN/MADD domain containing 2D
 3286
 0.17
chr9_82938706_82938857 0.17 Phip
 pleckstrin homology domain interacting protein
 5749
 0.26
chr17_25447727_25447880 0.17 Tekt4
 tektin 4
 6812
 0.12
chr2_23090654_23090815 0.16 Acbd5
 acyl-Coenzyme A binding domain containing 5
 3467
 0.23
chr14_76800394_76800719 0.16 Gm30246
 predicted gene, 30246
 19729
 0.17
chr8_89207204_89207384 0.16 Gm5356
 predicted pseudogene 5356
 19734
 0.24
chr10_24362809_24362960 0.16 Gm15271
 predicted gene 15271
 84606
 0.08
chr3_37687682_37687873 0.16 Gm43414
 predicted gene 43414
 20244
 0.1
chr16_44149582_44149733 0.16 Naa50
 N(alpha)-acetyltransferase 50, NatE catalytic subunit
 9765
 0.17
chr6_13676526_13676747 0.16 Bmt2
 base methyltransferase of 25S rRNA 2
 1302
 0.55
chr5_146330559_146330717 0.16 Cdk8
 cyclin-dependent kinase 8
 34273
 0.13
chr16_6901477_6901805 0.16 Rbfox1
 RNA binding protein, fox-1 homolog (C. elegans) 1
 92419
 0.1
chr8_68008523_68008836 0.16 Gm22018
 predicted gene, 22018
 1661
 0.43
chr13_23849104_23849255 0.16 Slc17a3
 solute carrier family 17 (sodium phosphate), member 3
 9589
 0.08
chr9_106727325_106727482 0.16 Rad54l2
 RAD54 like 2 (S. cerevisiae)
 4532
 0.19
chrX_109011797_109011968 0.16 Hmgn5
 high-mobility group nucleosome binding domain 5
 1522
 0.29
chr9_22467234_22467805 0.16 Rp9
 retinitis pigmentosa 9 (human)
 651
 0.58
chr9_108797332_108797857 0.16 Ip6k2
 inositol hexaphosphate kinase 2
 593
 0.53
chr8_44937447_44937668 0.16 Fat1
 FAT atypical cadherin 1
 2110
 0.3
chr15_77929755_77929928 0.15 Txn2
 thioredoxin 2
 835
 0.54
chr12_91731624_91731976 0.15 Ston2
 stonin 2
 12055
 0.17
chr15_27461169_27461365 0.15 Gm36899
 predicted gene, 36899
 2182
 0.26
chr3_121778871_121779078 0.15 4633401B06Rik
 RIKEN cDNA 4633401B06 gene
 9598
 0.11
chr8_119925715_119925866 0.15 Usp10
 ubiquitin specific peptidase 10
 11892
 0.16
chr11_74648732_74649171 0.15 Cluh
 clustered mitochondria (cluA/CLU1) homolog
 544
 0.74
chr5_142614394_142614571 0.15 Mmd2
 monocyte to macrophage differentiation-associated 2
 5682
 0.16
chr4_36131854_36132041 0.15 Lingo2
 leucine rich repeat and Ig domain containing 2
 4516
 0.35
chrY_90796785_90796987 0.15 Gm47283
 predicted gene, 47283
 6435
 0.19
chr4_149989662_149989976 0.15 H6pd
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 11446
 0.15
chr10_71177574_71177846 0.15 1700113B09Rik
 RIKEN cDNA 1700113B09 gene
 3326
 0.15
chr6_37705705_37706037 0.15 Ybx1-ps2
 Y box protein 1, pseudogene 2
 18676
 0.24

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.5 GO:0006549 isoleucine metabolic process(GO:0006549)
0.1 0.3 GO:0006808 regulation of nitrogen utilization(GO:0006808)
0.1 0.2 GO:0052041 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.1 0.3 GO:0071476 cellular hypotonic response(GO:0071476)
0.1 0.3 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.2 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0015842 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0 0.1 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.1 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:1904017 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0070948 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0070346 positive regulation of fat cell proliferation(GO:0070346)
0.0 0.1 GO:0000103 sulfate assimilation(GO:0000103)
0.0 0.0 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0 0.2 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.0 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:2001180 negative regulation of interleukin-10 secretion(GO:2001180)
0.0 0.1 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.0 GO:0048294 negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0 0.0 GO:0003340 negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0 0.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.0 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.0 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.1 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.0 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0 0.0 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 1.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.1 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.2 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.0 GO:0005879 axonemal microtubule(GO:0005879)
0.0 0.0 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.2 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.2 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.4 GO:0031559 oxidosqualene cyclase activity(GO:0031559)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 1.3 GO:0080032 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0042392 sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0 0.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.4 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.0 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.3 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.0 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation