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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Pou3f4

Z-value: 1.18

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Transcription factors associated with Pou3f4

Gene Symbol	Gene ID	Gene Info
Pou3f4 Ensembl NCBI MGI UniProt	ENSMUSG00000056854.3	Pou3f4

Activity of the Pou3f4 motif across conditions

Conditions sorted by the z-value of the Pou3f4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_145775927_145776137	1.43	Ddah1	dimethylarginine dimethylaminohydrolase 1	15284	0.2
chr2_177500562_177500734	1.26	Gm14403	predicted gene 14403	2333	0.26
chr11_11946176_11946345	1.16	Grb10	growth factor receptor bound protein 10	70	0.98
chr19_40153747_40153898	1.08	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	33464	0.13
chr19_40159590_40159741	1.02	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	27621	0.14
chr8_105104839_105104994	0.95	Gm8804	predicted gene 8804	5708	0.11
chr12_104343910_104344587	0.94	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	5762	0.12
chr11_111269853_111270023	0.90	Gm11675	predicted gene 11675	6162	0.34
chr2_73628966_73629117	0.87	Chn1	chimerin 1	3301	0.21
chr11_5905326_5905477	0.80	Gck	glucokinase	3314	0.14
chr10_24362809_24362960	0.78	Gm15271	predicted gene 15271	84606	0.08
chr13_82200374_82200525	0.76	Gm48155	predicted gene, 48155	110692	0.07
chr9_74893793_74894014	0.76	Onecut1	one cut domain, family member 1	27419	0.13
chr18_38370754_38370932	0.70	Gm4949	predicted gene 4949	10305	0.12
chr10_87880307_87880601	0.67	Igf1os	insulin-like growth factor 1, opposite strand	17073	0.18
chr8_93183570_93183871	0.66	Gm45909	predicted gene 45909	7638	0.14
chr7_35748679_35748830	0.62	Dpy19l3	dpy-19-like 3 (C. elegans)	5601	0.2
chr8_84761164_84761339	0.61	Nfix	nuclear factor I/X	12145	0.11
chr4_108093158_108093452	0.61	Podn	podocan	3140	0.19
chr12_57317079_57317230	0.61	Mipol1	mirror-image polydactyly 1	11071	0.22
chr6_149147053_149147326	0.59	Etfbkmt	electron transfer flavoprotein beta subunit lysine methyltransferase	5543	0.14
chr1_162987951_162988105	0.58	Fmo3	flavin containing monooxygenase 3	3500	0.2
chr19_40165767_40165918	0.57	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	21444	0.14
chr15_62744471_62744634	0.56	Gm22521	predicted gene, 22521	48649	0.17
chr10_24362567_24362800	0.55	Gm15271	predicted gene 15271	84807	0.08
chr12_32766682_32766844	0.55	Nampt	nicotinamide phosphoribosyltransferase	52782	0.12
chr7_26817080_26817232	0.55	Cyp2g1	cytochrome P450, family 2, subfamily g, polypeptide 1	861	0.56
chr13_112331091_112331250	0.54	Ankrd55	ankyrin repeat domain 55	12716	0.17
chr12_86515829_86515996	0.54	Esrrb	estrogen related receptor, beta	11503	0.25
chr5_107123329_107123511	0.54	Tgfbr3	transforming growth factor, beta receptor III	9503	0.17
chr8_93164567_93164980	0.53	Ces1d	carboxylesterase 1D	5202	0.15
chr1_102517902_102518283	0.52	Gm20281	predicted gene, 20281	59170	0.14
chr5_3492308_3492470	0.52	Gm42435	predicted gene 42435	7683	0.13
chr4_135221446_135221961	0.52	Clic4	chloride intracellular channel 4 (mitochondrial)	51111	0.09
chr11_16865620_16865819	0.52	Egfr	epidermal growth factor receptor	12431	0.2
chr12_99858543_99858709	0.51	Efcab11	EF-hand calcium binding domain 11	24231	0.11
chr5_125522690_125522841	0.50	Aacs	acetoacetyl-CoA synthetase	7522	0.16
chr2_58777467_58777618	0.50	Upp2	uridine phosphorylase 2	12217	0.2
chr8_93165222_93165456	0.50	Ces1d	carboxylesterase 1D	4636	0.15
chr5_87570105_87570260	0.50	Sult1d1	sulfotransferase family 1D, member 1	1155	0.34
chr7_114356842_114356993	0.48	4933406I18Rik	RIKEN cDNA 4933406I18 gene	58104	0.11
chr12_104083020_104083260	0.48	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	2491	0.16
chr9_70446864_70447026	0.48	Rnf111	ring finger 111	6901	0.16
chr12_45069728_45070323	0.47	Stxbp6	syntaxin binding protein 6 (amisyn)	4087	0.24
chr10_127702413_127702583	0.47	Myo1a	myosin IA	2672	0.12
chr2_73491256_73491419	0.47	Wipf1	WAS/WASL interacting protein family, member 1	4868	0.19
chr19_53781327_53781513	0.47	Rbm20	RNA binding motif protein 20	11888	0.17
chr19_26823641_26823967	0.46	4931403E22Rik	RIKEN cDNA 4931403E22 gene	103	0.97
chr5_87589802_87589979	0.46	Sult1e1	sulfotransferase family 1E, member 1	1704	0.22
chr19_44399803_44399962	0.45	Scd1	stearoyl-Coenzyme A desaturase 1	6808	0.15
chr1_151124767_151124929	0.45	Gm8941	predicted gene 8941	11659	0.12
chr1_58945674_58946262	0.45	Trak2	trafficking protein, kinesin binding 2	369	0.84
chr9_106727325_106727482	0.45	Rad54l2	RAD54 like 2 (S. cerevisiae)	4532	0.19
chr2_72160606_72160802	0.45	Rapgef4os1	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 1	11908	0.19
chr3_41138122_41138276	0.45	Gm40038	predicted gene, 40038	34464	0.16
chr16_90199102_90199289	0.44	Gm49704	predicted gene, 49704	1047	0.47
chr6_114877506_114877696	0.44	Vgll4	vestigial like family member 4	2494	0.3
chr16_18187141_18187312	0.44	Mir6366	microRNA 6366	22056	0.08
chr2_58783629_58783834	0.44	Upp2	uridine phosphorylase 2	18406	0.19
chr11_28696545_28697113	0.43	2810471M01Rik	RIKEN cDNA 2810471M01 gene	15265	0.17
chr16_37902225_37902391	0.43	Gpr156	G protein-coupled receptor 156	14188	0.14
chr1_151121601_151121803	0.42	Gm19087	predicted gene, 19087	13787	0.12
chr10_76531927_76532170	0.42	Lss	lanosterol synthase	366	0.79
chr1_21261382_21261702	0.42	Gsta3	glutathione S-transferase, alpha 3	8021	0.11
chr1_151720665_151721037	0.41	2810414N06Rik	RIKEN cDNA 2810414N06 gene	34167	0.14
chr4_76468484_76468676	0.41	Gm42303	predicted gene, 42303	17349	0.21
chr3_51185131_51185304	0.41	Noct	nocturnin	39230	0.12
chr4_35916085_35916245	0.41	Lingo2	leucine rich repeat and Ig domain containing 2	70961	0.13
chr17_28428613_28428954	0.40	Fkbp5	FK506 binding protein 5	154	0.91
chr2_8124301_8124468	0.40	Gm13254	predicted gene 13254	23481	0.29
chr4_15023934_15024314	0.40	Gm11844	predicted gene 11844	1542	0.5
chr15_59056231_59056593	0.40	Mtss1	MTSS I-BAR domain containing 1	948	0.63
chr4_3373115_3373279	0.40	Gm11784	predicted gene 11784	13649	0.2
chr7_4814980_4815131	0.40	Ube2s	ubiquitin-conjugating enzyme E2S	2465	0.12
chr9_74326904_74327074	0.40	Gm24141	predicted gene, 24141	35621	0.16
chr1_21266470_21266781	0.40	Gm28836	predicted gene 28836	4968	0.12
chr3_18137155_18137306	0.40	Gm23686	predicted gene, 23686	40395	0.15
chr3_89896247_89896398	0.40	Gm42809	predicted gene 42809	16594	0.11
chr6_85810872_85811030	0.40	Nat8f6	N-acetyltransferase 8 (GCN5-related) family member 6	1088	0.31
chr1_164435834_164435997	0.39	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	7804	0.15
chr5_150918259_150918412	0.39	Kl	klotho	34272	0.15
chr4_35533897_35534048	0.39	Gm12365	predicted gene 12365	97758	0.08
chr15_62533627_62533818	0.39	Gm41333	predicted gene, 41333	34253	0.23
chr3_116302483_116302634	0.39	Gm29151	predicted gene 29151	47545	0.11
chr16_37874612_37874787	0.39	Lrrc58	leucine rich repeat containing 58	6310	0.14
chr2_58782728_58782879	0.39	Upp2	uridine phosphorylase 2	17478	0.19
chr7_119957531_119957709	0.39	Dnah3	dynein, axonemal, heavy chain 3	5463	0.17
chr11_111998446_111998808	0.39	Gm11679	predicted gene 11679	44951	0.19
chr4_109801705_109801878	0.39	Faf1	Fas-associated factor 1	38994	0.16
chr11_120804691_120805015	0.38	Fasn	fatty acid synthase	3752	0.1
chr5_122017137_122017617	0.38	Gm3970	predicted gene 3970	7953	0.16
chr1_67181891_67182275	0.38	Cps1	carbamoyl-phosphate synthetase 1	59057	0.11
chr19_12700970_12701121	0.38	Keg1	kidney expressed gene 1	5231	0.11
chr15_3511597_3511812	0.38	Ghr	growth hormone receptor	40060	0.19
chr13_62893171_62893343	0.38	Fbp1	fructose bisphosphatase 1	4975	0.16
chr3_14832193_14832481	0.37	Car1	carbonic anhydrase 1	23969	0.15
chr9_74328635_74328791	0.37	Gm24141	predicted gene, 24141	33897	0.17
chr4_48261059_48261322	0.37	Erp44	endoplasmic reticulum protein 44	16716	0.18
chr4_123990393_123990580	0.37	Gm12902	predicted gene 12902	64252	0.08
chr3_141967234_141967427	0.37	Bmpr1b	bone morphogenetic protein receptor, type 1B	14934	0.29
chr1_159269464_159269648	0.37	Cop1	COP1, E3 ubiquitin ligase	2822	0.24
chr19_40164076_40164449	0.37	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	23024	0.14
chr19_17311642_17311793	0.37	Gcnt1	glucosaminyl (N-acetyl) transferase 1, core 2	23719	0.17
chr5_142614394_142614571	0.36	Mmd2	monocyte to macrophage differentiation-associated 2	5682	0.16
chr4_134837028_134837206	0.36	Maco1	macoilin 1	16032	0.17
chr12_98524945_98525096	0.36	Gm40893	predicted gene, 40893	1176	0.44
chr8_26078485_26078636	0.36	Hook3	hook microtubule tethering protein 3	817	0.46
chr12_103937089_103937240	0.36	Gm17198	predicted gene 17198	10873	0.1
chr10_4605236_4605428	0.36	Esr1	estrogen receptor 1 (alpha)	6261	0.23
chr8_80982761_80982912	0.35	Gm9725	predicted gene 9725	30740	0.13
chr3_18148711_18148862	0.35	Gm23686	predicted gene, 23686	28839	0.19
chr2_58773911_58774203	0.35	Upp2	uridine phosphorylase 2	8732	0.21
chr4_100790971_100791127	0.35	Cachd1	cache domain containing 1	14374	0.28
chr10_69208679_69208830	0.35	Rhobtb1	Rho-related BTB domain containing 1	202	0.94
chr2_17326719_17326870	0.34	Nebl	nebulette	34292	0.22
chr5_96738098_96738279	0.34	Gm42604	predicted gene 42604	1176	0.5
chr16_77416854_77417005	0.34	Gm38071	predicted gene, 38071	305	0.82
chr3_148832133_148832284	0.34	Adgrl2	adhesion G protein-coupled receptor L2	1720	0.51
chr14_57826803_57826983	0.34	Mrpl57	mitochondrial ribosomal protein L57	463	0.54
chr4_53154081_53154232	0.33	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	5739	0.24
chr12_32678889_32679054	0.33	Gm47937	predicted gene, 47937	5677	0.25
chr3_58519897_58520081	0.33	Eif2a	eukaryotic translation initiation factor 2A	5832	0.16
chr19_17761720_17761899	0.33	Gm17819	predicted gene, 17819	69046	0.1
chr14_116240919_116241084	0.33	Gm20713	predicted gene 20713	369723	0.01
chr18_76254679_76254860	0.33	Smad2	SMAD family member 2	6352	0.2
chr11_16862337_16862489	0.33	Egfr	epidermal growth factor receptor	15737	0.19
chr4_47366562_47366857	0.33	Tgfbr1	transforming growth factor, beta receptor I	13099	0.22
chr10_67192820_67193057	0.33	Jmjd1c	jumonji domain containing 1C	7185	0.22
chr6_119739379_119739563	0.33	Erc1	ELKS/RAB6-interacting/CAST family member 1	3973	0.32
chr6_116079297_116079457	0.33	Tmcc1	transmembrane and coiled coil domains 1	6221	0.18
chr16_42908040_42908286	0.33	Zbtb20	zinc finger and BTB domain containing 20	511	0.78
chr11_120241116_120241542	0.33	Bahcc1	BAH domain and coiled-coil containing 1	4630	0.11
chr10_78618331_78618509	0.32	Olfr1357	olfactory receptor 1357	346	0.74
chr6_51695749_51695900	0.32	Gm38811	predicted gene, 38811	15257	0.23
chr17_56573047_56573233	0.32	Safb2	scaffold attachment factor B2	642	0.57
chr10_8642632_8642823	0.32	Gm24374	predicted gene, 24374	207	0.96
chr2_72222188_72222339	0.32	Rapgef4os2	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 2	10039	0.17
chr4_134899949_134900100	0.32	Tmem50a	transmembrane protein 50A	14991	0.14
chr6_114812242_114812393	0.32	Gm44331	predicted gene, 44331	22927	0.16
chr5_28465358_28465587	0.32	9530036O11Rik	RIKEN cDNA 9530036O11Rik	1512	0.34
chr6_85763479_85763641	0.32	Nat8f3	N-acetyltransferase 8 (GCN5-related) family member 3	1080	0.33
chr16_37630277_37630428	0.32	Hgd	homogentisate 1, 2-dioxygenase	8503	0.16
chr15_3496511_3496663	0.32	Ghr	growth hormone receptor	24943	0.24
chr11_16696870_16697220	0.32	Gm25698	predicted gene, 25698	35666	0.13
chr8_25256630_25256805	0.31	Tacc1	transforming, acidic coiled-coil containing protein 1	129	0.97
chr2_122158054_122158205	0.31	Trim69	tripartite motif-containing 69	2571	0.17
chr4_108096711_108097042	0.31	Podn	podocan	431	0.78
chr16_24449611_24449762	0.31	Lpp	LIM domain containing preferred translocation partner in lipoma	1595	0.42
chr2_122263270_122263421	0.31	Duox2	dual oxidase 2	22224	0.09
chr5_114177314_114177465	0.31	Acacb	acetyl-Coenzyme A carboxylase beta	1483	0.33
chr2_109684188_109684342	0.31	Bdnf	brain derived neurotrophic factor	7233	0.19
chr6_141854319_141854470	0.31	Slco1a4	solute carrier organic anion transporter family, member 1a4	712	0.71
chr18_33435778_33435929	0.31	Nrep	neuronal regeneration related protein	27582	0.18
chr11_72830025_72830176	0.31	Gm6733	predicted gene 6733	3361	0.19
chr14_73382429_73382580	0.31	Itm2b	integral membrane protein 2B	2694	0.29
chr4_90082681_90082858	0.30	Gm12629	predicted gene 12629	102758	0.08
chr11_119048222_119048411	0.30	Cbx8	chromobox 8	7347	0.16
chr18_61565305_61565485	0.30	Csnk1a1	casein kinase 1, alpha 1	9706	0.15
chr6_15930296_15930597	0.30	Gm43990	predicted gene, 43990	94357	0.08
chr6_144708083_144708633	0.30	Sox5os4	SRY (sex determining region Y)-box 5, opposite strand 4	12553	0.16
chr16_57130407_57130558	0.30	Tomm70a	translocase of outer mitochondrial membrane 70A	7016	0.17
chrX_151491088_151491256	0.30	Gm15148	predicted gene 15148	2097	0.3
chr18_35458247_35458406	0.30	Gm50145	predicted gene, 50145	30778	0.1
chr6_50091657_50091996	0.30	Mpp6	membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)	18415	0.22
chr4_97100282_97100474	0.30	Gm27521	predicted gene, 27521	183358	0.03
chr18_8933337_8933488	0.30	Gm37148	predicted gene, 37148	5177	0.27
chr13_52819486_52819637	0.29	BB123696	expressed sequence BB123696	62356	0.13
chr3_18107731_18107882	0.29	Gm23726	predicted gene, 23726	38480	0.15
chr5_65999373_65999558	0.29	9130230L23Rik	RIKEN cDNA 9130230L23 gene	753	0.52
chr5_100424142_100424293	0.29	5430416N02Rik	RIKEN cDNA 5430416N02 gene	5158	0.15
chr10_14012990_14013158	0.29	Hivep2	human immunodeficiency virus type I enhancer binding protein 2	46050	0.14
chr3_105773852_105774003	0.29	Gm43329	predicted gene 43329	3730	0.13
chr9_24502048_24502199	0.29	Dpy19l1	dpy-19-like 1 (C. elegans)	1017	0.45
chr1_105176971_105177328	0.29	Gm29012	predicted gene 29012	60695	0.12
chr8_93165469_93165620	0.29	Ces1d	carboxylesterase 1D	4431	0.16
chr10_50623725_50623913	0.29	Ascc3	activating signal cointegrator 1 complex subunit 3	18623	0.22
chr16_56714341_56714503	0.29	Tfg	Trk-fused gene	1446	0.47
chr5_107832772_107832923	0.29	Ube2d2b	ubiquitin-conjugating enzyme E2D 2B	2748	0.16
chr9_74872523_74872674	0.29	Onecut1	one cut domain, family member 1	6114	0.16
chr7_88307523_88307674	0.29	Gm44751	predicted gene 44751	3880	0.23
chr8_22873332_22873513	0.29	Gm45555	predicted gene 45555	167	0.94
chr1_69685147_69685314	0.29	Ikzf2	IKAROS family zinc finger 2	70	0.98
chr1_56623913_56624064	0.28	Hsfy2	heat shock transcription factor, Y-linked 2	13447	0.28
chr15_3397234_3397385	0.28	Ghr	growth hormone receptor	74335	0.1
chr5_98992026_98992185	0.28	Prkg2	protein kinase, cGMP-dependent, type II	25349	0.2
chr17_71222209_71222384	0.28	Lpin2	lipin 2	9137	0.17
chr7_46746742_46746969	0.28	Saa1	serum amyloid A 1	3875	0.1
chr17_80022007_80022158	0.28	Gm22215	predicted gene, 22215	11432	0.14
chr19_57872901_57873092	0.28	Mir5623	microRNA 5623	178171	0.03
chr1_67133525_67134193	0.28	Cps1	carbamoyl-phosphate synthetase 1	10833	0.24
chr11_28694849_28695038	0.28	2810471M01Rik	RIKEN cDNA 2810471M01 gene	13379	0.17
chr12_16875027_16875348	0.28	Rock2	Rho-associated coiled-coil containing protein kinase 2	19708	0.13
chr14_117938790_117938941	0.28	Mir6239	microRNA 6239	14982	0.25
chr5_87147107_87147418	0.28	Ugt2b5	UDP glucuronosyltransferase 2 family, polypeptide B5	6944	0.13
chr11_28685236_28685405	0.28	2810471M01Rik	RIKEN cDNA 2810471M01 gene	3756	0.24
chr3_31993839_31993990	0.28	Gm37834	predicted gene, 37834	39150	0.2
chr3_149240098_149240249	0.28	Gm10287	predicted gene 10287	14428	0.2
chr2_148027677_148027828	0.28	9030622O22Rik	RIKEN cDNA 9030622O22 gene	10518	0.17
chr11_84185943_84186094	0.28	Gm37391	predicted gene, 37391	3575	0.21
chr10_89472531_89472682	0.27	Gas2l3	growth arrest-specific 2 like 3	28639	0.18

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou3f4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.3	0.8	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	1.2	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.2	0.7	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.5	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.3	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1	0.6	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.3	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.4	GO:0001834	trophectodermal cell proliferation(GO:0001834)
0.1	0.2	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.2	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.2	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	0.5	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.3	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.2	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	1.8	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.1	0.5	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	0.1	GO:0061317	canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:0061317)
0.1	0.2	GO:0006083	acetate metabolic process(GO:0006083)
0.1	0.3	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.1	0.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.2	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1	0.2	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.1	0.2	GO:0072592	oxygen metabolic process(GO:0072592)
0.1	0.1	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1	0.3	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.3	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.0	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.1	GO:2001245	regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.2	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.2	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.1	GO:0061535	glutamate secretion, neurotransmission(GO:0061535)
0.0	0.3	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.3	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.2	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.2	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.2	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0006971	hypotonic response(GO:0006971)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.0	GO:0061346	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.2	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.2	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.1	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:1904690	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0	0.1	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.8	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:0019740	nitrogen utilization(GO:0019740)
0.0	0.1	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.0	GO:1900094	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.7	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.3	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.1	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0043553	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.3	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.2	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.2	GO:0045176	apical protein localization(GO:0045176)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.0	GO:0048382	mesendoderm development(GO:0048382)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.0	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.1	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.2	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.1	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:1903286	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.3	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.1	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.1	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.0	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.1	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.1	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.2	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.2	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.1	GO:2000172	regulation of branching morphogenesis of a nerve(GO:2000172)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.1	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.0	0.1	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0035799	ureter maturation(GO:0035799)
0.0	0.0	GO:2001025	positive regulation of response to drug(GO:2001025)
0.0	0.1	GO:0015822	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.1	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.1	GO:0009312	oligosaccharide biosynthetic process(GO:0009312)
0.0	0.0	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.0	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.1	GO:1902177	positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902177)
0.0	0.0	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:1902222	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.2	GO:0048172	regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0	0.1	GO:0030206	chondroitin sulfate biosynthetic process(GO:0030206)
0.0	0.1	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.0	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.0	0.0	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.0	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0010807	regulation of synaptic vesicle priming(GO:0010807)
0.0	0.0	GO:1902065	response to L-glutamate(GO:1902065)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.0	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.0	GO:0060161	positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.0	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.1	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.0	GO:0036394	amylase secretion(GO:0036394)
0.0	0.0	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.0	0.4	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.0	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.0	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.2	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.0	0.2	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:0046104	thymidine metabolic process(GO:0046104) pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0060352	cell adhesion molecule production(GO:0060352)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.0	GO:0035627	ceramide transport(GO:0035627)
0.0	0.0	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0060394	negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0	0.5	GO:1904893	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0021707	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.2	GO:0055070	copper ion homeostasis(GO:0055070)
0.0	0.4	GO:0048536	spleen development(GO:0048536)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0045213	neurotransmitter receptor metabolic process(GO:0045213)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.1	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.0	0.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.2	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0030579	ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0	0.0	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.0	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.0	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.0	GO:0097240	meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.0	GO:0032439	endosome localization(GO:0032439)
0.0	0.0	GO:0090154	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0031053	primary miRNA processing(GO:0031053)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.3	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.3	GO:0097433	dense body(GO:0097433)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0070695	FHF complex(GO:0070695)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.2	GO:0051286	cell tip(GO:0051286)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	1.1	GO:0005811	lipid particle(GO:0005811)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.1	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0098536	deuterosome(GO:0098536)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.0	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.2	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.0	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.0	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.0	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.0	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.6	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.4	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.4	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.8	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.3	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.3	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.4	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.2	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.2	GO:0038181	bile acid receptor activity(GO:0038181)
0.1	1.1	GO:0001784	phosphotyrosine binding(GO:0001784)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.2	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.3	GO:0031559	oxidosqualene cyclase activity(GO:0031559)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.7	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	1.4	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:0045545	syndecan binding(GO:0045545)
0.0	0.9	GO:0034892	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.8	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.3	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.3	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.3	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.3	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.5	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.1	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.1	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.0	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.3	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.3	GO:0016709	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0	1.4	GO:0005496	steroid binding(GO:0005496)
0.0	0.1	GO:0070728	leucine binding(GO:0070728)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.0	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.0	GO:0004946	bombesin receptor activity(GO:0004946)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.4	GO:0001540	beta-amyloid binding(GO:0001540)
0.0	0.3	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.0	GO:0002046	opsin binding(GO:0002046)
0.0	0.2	GO:0004659	prenyltransferase activity(GO:0004659)
0.0	0.0	GO:0005219	ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.0	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.2	GO:0005328	neurotransmitter:sodium symporter activity(GO:0005328)
0.0	0.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0032183	SUMO binding(GO:0032183)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.0	GO:0097001	ceramide binding(GO:0097001)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.1	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.0	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.0	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0008097	5S rRNA binding(GO:0008097)
0.0	0.1	GO:0008454	alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0	0.0	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.0	GO:0019203	carbohydrate phosphatase activity(GO:0019203)
0.0	0.0	GO:0016015	morphogen activity(GO:0016015)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.0	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.3	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.3	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.4	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.5	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.7	PID HES HEY PATHWAY	Notch-mediated HES/HEY network
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.5	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.0	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.4	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.2	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.0	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	1.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.5	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.7	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.4	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.5	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.1	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0	0.1	REACTOME BIOLOGICAL OXIDATIONS	Genes involved in Biological oxidations
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.0	REACTOME RNA POL I TRANSCRIPTION	Genes involved in RNA Polymerase I Transcription
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling