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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Prop1

Z-value: 1.29

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Transcription factors associated with Prop1

Gene Symbol	Gene ID	Gene Info
Prop1 Ensembl NCBI MGI UniProt	ENSMUSG00000044542.3	paired like homeodomain factor 1

Activity of the Prop1 motif across conditions

Conditions sorted by the z-value of the Prop1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_124590350_124590536	1.85	4930503E24Rik	RIKEN cDNA 4930503E24 gene	67005	0.14
chr10_87040962_87041138	1.46	1700113H08Rik	RIKEN cDNA 1700113H08 gene	16995	0.16
chr16_43169836_43170008	1.26	Gm15712	predicted gene 15712	14651	0.21
chr17_79018863_79019084	1.18	Prkd3	protein kinase D3	1804	0.3
chr19_12613616_12613767	1.12	Gm4952	predicted gene 4952	13675	0.09
chr5_86919547_86919811	1.12	Gm25211	predicted gene, 25211	3357	0.13
chr8_110644559_110644860	1.11	Vac14	Vac14 homolog (S. cerevisiae)	871	0.63
chr17_80022007_80022158	0.99	Gm22215	predicted gene, 22215	11432	0.14
chr9_74672657_74672818	0.98	Gm27233	predicted gene 27233	36525	0.18
chr8_76152735_76152886	0.98	Gm45742	predicted gene 45742	35783	0.19
chr6_24610042_24610446	0.97	Lmod2	leiomodin 2 (cardiac)	12482	0.14
chr1_100298746_100298897	0.95	Gm29667	predicted gene 29667	16030	0.18
chr16_79086922_79087073	0.94	Tmprss15	transmembrane protease, serine 15	4095	0.35
chr7_97411671_97412103	0.93	Thrsp	thyroid hormone responsive	5632	0.13
chr3_95879412_95879563	0.92	Ciart	circadian associated repressor of transcription	1759	0.16
chr9_74885383_74885534	0.91	Onecut1	one cut domain, family member 1	18974	0.14
chr4_76942367_76942518	0.90	Gm11246	predicted gene 11246	15131	0.21
chr4_47366562_47366857	0.90	Tgfbr1	transforming growth factor, beta receptor I	13099	0.22
chr1_140421414_140421565	0.85	Kcnt2	potassium channel, subfamily T, member 2	21447	0.27
chr10_87868820_87868971	0.85	Igf1os	insulin-like growth factor 1, opposite strand	5514	0.22
chr1_21259850_21260251	0.85	Gsta3	glutathione S-transferase, alpha 3	6529	0.11
chr3_76637152_76637321	0.84	Fstl5	follistatin-like 5	43686	0.19
chr5_100369426_100369577	0.83	Sec31a	Sec31 homolog A (S. cerevisiae)	3983	0.2
chr15_38049613_38049764	0.83	Gm22353	predicted gene, 22353	8597	0.16
chr8_109981175_109981347	0.82	Gm45795	predicted gene 45795	6909	0.13
chr10_4617695_4617851	0.81	Esr1	estrogen receptor 1 (alpha)	5752	0.25
chr13_115653702_115653853	0.80	Gm47892	predicted gene, 47892	65722	0.13
chr12_51274477_51274668	0.79	Rps11-ps4	ribosomal protein S11, pseudogene 4	22915	0.22
chrX_49489499_49489695	0.79	Arhgap36	Rho GTPase activating protein 36	3922	0.27
chr4_121078016_121078199	0.79	Zmpste24	zinc metallopeptidase, STE24	369	0.74
chr9_74881714_74881880	0.78	Onecut1	one cut domain, family member 1	15313	0.15
chr2_18435403_18435565	0.77	Dnajc1	DnaJ heat shock protein family (Hsp40) member C1	42654	0.16
chr2_64059065_64059258	0.77	Fign	fidgetin	38827	0.23
chr10_87936931_87937082	0.76	Tyms-ps	thymidylate synthase, pseudogene	29841	0.15
chr4_101198122_101198415	0.74	Gm24468	predicted gene, 24468	11504	0.14
chr12_105824675_105824843	0.74	Papola	poly (A) polymerase alpha	4308	0.21
chr2_121507198_121507349	0.72	Wdr76	WD repeat domain 76	490	0.46
chr2_177468355_177468573	0.72	Zfp970	zinc finger protein 970	3618	0.19
chr5_87589802_87589979	0.72	Sult1e1	sulfotransferase family 1E, member 1	1704	0.22
chr2_38823684_38823849	0.72	Nr6a1os	nuclear receptor subfamily 6, group A, member 1, opposite strand	425	0.74
chr2_31499430_31499808	0.71	Ass1	argininosuccinate synthetase 1	1107	0.5
chr2_31519719_31520357	0.69	Ass1	argininosuccinate synthetase 1	1548	0.36
chr1_124069161_124069328	0.69	Dpp10	dipeptidylpeptidase 10	23685	0.27
chr18_53860444_53860644	0.68	Csnk1g3	casein kinase 1, gamma 3	1578	0.52
chr8_76147788_76147939	0.68	Gm45742	predicted gene 45742	30836	0.21
chr5_90899182_90899382	0.68	Cxcl2	chemokine (C-X-C motif) ligand 2	4589	0.13
chr13_63113927_63114104	0.67	Aopep	aminopeptidase O	6493	0.16
chr9_106245058_106245282	0.66	Alas1	aminolevulinic acid synthase 1	1536	0.23
chr3_18137155_18137306	0.66	Gm23686	predicted gene, 23686	40395	0.15
chr3_144109828_144110050	0.66	Gm34078	predicted gene, 34078	25815	0.2
chr8_93245968_93246147	0.66	Gm45727	predicted gene 45727	5118	0.15
chr10_87032560_87032752	0.65	Stab2	stabilin 2	24631	0.14
chr4_90082681_90082858	0.65	Gm12629	predicted gene 12629	102758	0.08
chr2_53178520_53178671	0.64	Prpf40a	pre-mRNA processing factor 40A	11505	0.23
chr11_16888258_16888409	0.64	Egfr	epidermal growth factor receptor	10183	0.2
chr10_93196295_93196461	0.64	Cdk17	cyclin-dependent kinase 17	10609	0.2
chr6_146271566_146271772	0.64	Gm44086	predicted gene, 44086	689	0.74
chr11_120238015_120238347	0.63	Bahcc1	BAH domain and coiled-coil containing 1	1482	0.22
chr6_122571659_122571823	0.63	Gm16556	predicted gene 16556	892	0.4
chr2_77543027_77543190	0.63	Zfp385b	zinc finger protein 385B	18872	0.25
chr3_60099135_60099299	0.63	Sucnr1	succinate receptor 1	17315	0.18
chr13_69640079_69640317	0.62	Nsun2	NOL1/NOP2/Sun domain family member 2	9458	0.1
chr8_104787437_104787637	0.62	Gm45782	predicted gene 45782	1709	0.21
chr14_34316954_34317105	0.62	Glud1	glutamate dehydrogenase 1	6302	0.11
chr8_93183570_93183871	0.62	Gm45909	predicted gene 45909	7638	0.14
chr11_28696253_28696446	0.61	2810471M01Rik	RIKEN cDNA 2810471M01 gene	14785	0.17
chr9_24922429_24922589	0.61	Gm48255	predicted gene, 48255	30464	0.13
chr2_134708873_134709037	0.61	Gm14037	predicted gene 14037	22152	0.2
chr1_67150788_67150939	0.61	Cps1	carbamoyl-phosphate synthetase 1	27837	0.2
chr5_99976807_99976958	0.61	Hnrnpd	heterogeneous nuclear ribonucleoprotein D	331	0.73
chr4_148615928_148616079	0.61	Tardbp	TAR DNA binding protein	135	0.93
chr2_65212598_65212873	0.60	Cobll1	Cobl-like 1	23260	0.17
chr6_71999696_71999905	0.60	Gm26628	predicted gene, 26628	36025	0.1
chr9_109966945_109967106	0.60	Map4	microtubule-associated protein 4	1992	0.21
chr3_94710144_94710297	0.60	Selenbp2	selenium binding protein 2	16561	0.1
chr11_16834846_16835011	0.59	Egfros	epidermal growth factor receptor, opposite strand	4226	0.25
chr1_67222842_67222998	0.59	Gm15668	predicted gene 15668	26280	0.19
chr6_119681087_119681251	0.59	Erc1	ELKS/RAB6-interacting/CAST family member 1	59064	0.13
chr16_26702287_26702472	0.59	Il1rap	interleukin 1 receptor accessory protein	20055	0.24
chr3_94717786_94717937	0.58	Gm43711	predicted gene 43711	19482	0.1
chr5_72948525_72948751	0.58	Slain2	SLAIN motif family, member 2	139	0.94
chrX_109145684_109145835	0.57	Gm14869	predicted gene 14869	24075	0.17
chr11_16798476_16798627	0.57	Egfros	epidermal growth factor receptor, opposite strand	32151	0.16
chr19_37507552_37507703	0.57	Exoc6	exocyst complex component 6	13252	0.16
chr5_33465811_33466048	0.57	Gm43851	predicted gene 43851	28465	0.15
chr7_67658992_67659201	0.57	Ttc23	tetratricopeptide repeat domain 23	3649	0.17
chr2_141998050_141998201	0.57	Fau-ps1	Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), pseudogene 1	159336	0.04
chr16_43234125_43234650	0.57	Zbtb20	zinc finger and BTB domain containing 20	1493	0.45
chr6_100267052_100267222	0.56	Gm44044	predicted gene, 44044	6561	0.17
chr18_75498893_75499229	0.56	Gm10532	predicted gene 10532	15584	0.25
chr2_8123996_8124147	0.55	Gm13254	predicted gene 13254	23794	0.29
chr6_55171107_55171477	0.55	Inmt	indolethylamine N-methyltransferase	3722	0.2
chr8_93235526_93235686	0.55	Ces1e	carboxylesterase 1E	5987	0.14
chr3_133725023_133725174	0.55	Gm40153	predicted gene, 40153	61707	0.1
chr9_55277952_55278103	0.55	Nrg4	neuregulin 4	5545	0.2
chr4_151043729_151043930	0.55	Per3	period circadian clock 3	836	0.56
chr6_108454056_108454259	0.55	Itpr1	inositol 1,4,5-trisphosphate receptor 1	4546	0.21
chr13_112500544_112500748	0.54	Il6st	interleukin 6 signal transducer	25600	0.14
chrX_61144273_61144442	0.54	Gm24396	predicted gene, 24396	1005	0.5
chr1_162891903_162892071	0.54	Fmo2	flavin containing monooxygenase 2	5472	0.19
chr2_146546861_146547083	0.54	4933406D12Rik	RIKEN cDNA 4933406D12 gene	4041	0.3
chr19_14226869_14227031	0.54	Gm26993	predicted gene, 26993	208579	0.02
chr16_37873974_37874125	0.54	Lrrc58	leucine rich repeat containing 58	5660	0.14
chr14_47294893_47295081	0.54	Mapk1ip1l	mitogen-activated protein kinase 1 interacting protein 1-like	3279	0.11
chr6_50561677_50561828	0.53	Cycs	cytochrome c, somatic	4197	0.12
chr1_160280517_160280905	0.53	Rabgap1l	RAB GTPase activating protein 1-like	6627	0.14
chr13_42723821_42724025	0.53	Phactr1	phosphatase and actin regulator 1	14342	0.24
chr1_4829620_4829787	0.53	Lypla1	lysophospholipase 1	7202	0.13
chr5_130227356_130227532	0.53	Gm42467	predicted gene 42467	1228	0.28
chr16_6366127_6366312	0.53	Rbfox1	RNA binding protein, fox-1 homolog (C. elegans) 1	17081	0.31
chr5_52147484_52147676	0.53	Gm43176	predicted gene 43176	5007	0.13
chr17_89653592_89653743	0.53	Gm50061	predicted gene, 50061	98859	0.09
chr2_84379041_84379217	0.52	Calcrl	calcitonin receptor-like	3771	0.25
chr19_12652059_12652547	0.52	Glyat	glycine-N-acyltransferase	12811	0.09
chr15_38105734_38106027	0.52	Gm49312	predicted gene, 49312	26778	0.13
chr1_21242443_21242594	0.51	Gsta3	glutathione S-transferase, alpha 3	1889	0.22
chr8_109995374_109995556	0.51	Tat	tyrosine aminotransferase	4959	0.13
chr18_42685880_42686031	0.51	C030004G16Rik	RIKEN cDNA C030004G16 gene	63496	0.1
chr1_67169083_67169234	0.51	Cps1	carbamoyl-phosphate synthetase 1	46132	0.15
chr10_86690190_86690443	0.51	Gm15344	predicted gene 15344	2779	0.1
chr9_44940562_44940729	0.51	Gm19121	predicted gene, 19121	15070	0.08
chr10_87921071_87921222	0.51	Tyms-ps	thymidylate synthase, pseudogene	45701	0.12
chr5_90364825_90365036	0.50	Ankrd17	ankyrin repeat domain 17	1255	0.37
chr3_158035265_158035416	0.50	Gm43362	predicted gene 43362	1069	0.28
chr15_58983651_58983950	0.50	4930544F09Rik	RIKEN cDNA 4930544F09 gene	336	0.87
chr17_64676171_64676533	0.50	Man2a1	mannosidase 2, alpha 1	37068	0.18
chr7_100610040_100610203	0.50	Mrpl48	mitochondrial ribosomal protein L48	1820	0.19
chr2_84996201_84996436	0.49	Prg3	proteoglycan 3	8103	0.12
chr8_5099240_5099445	0.49	Slc10a2	solute carrier family 10, member 2	6009	0.18
chrY_90792564_90792728	0.49	Gm47283	predicted gene, 47283	2195	0.29
chr6_17478662_17478867	0.49	Met	met proto-oncogene	12477	0.21
chr4_100290333_100290484	0.49	Gm12706	predicted gene 12706	71651	0.11
chr2_146325477_146325645	0.49	Gm14117	predicted gene 14117	20014	0.21
chr5_107123329_107123511	0.49	Tgfbr3	transforming growth factor, beta receptor III	9503	0.17
chr18_85490238_85490398	0.49	Gm7612	predicted gene 7612	226407	0.02
chr5_151246921_151247115	0.48	5430435K18Rik	RIKEN cDNA 5430435K18 gene	5287	0.21
chr5_150270318_150270506	0.48	Fry	FRY microtubule binding protein	10645	0.18
chr2_75698638_75698789	0.48	Nfe2l2	nuclear factor, erythroid derived 2, like 2	5776	0.13
chr8_93165469_93165620	0.48	Ces1d	carboxylesterase 1D	4431	0.16
chr11_38774641_38774792	0.48	Gm23520	predicted gene, 23520	23561	0.29
chr4_108060521_108060686	0.47	Scp2	sterol carrier protein 2, liver	10760	0.13
chr4_121164131_121164282	0.47	Rlf	rearranged L-myc fusion sequence	24328	0.11
chrY_90800880_90801048	0.47	Gm47283	predicted gene, 47283	10513	0.18
chr10_69208679_69208830	0.47	Rhobtb1	Rho-related BTB domain containing 1	202	0.94
chr19_39287276_39287531	0.47	Cyp2c29	cytochrome P450, family 2, subfamily c, polypeptide 29	329	0.91
chr1_60098880_60099160	0.47	Wdr12	WD repeat domain 12	375	0.68
chr4_6225587_6225787	0.46	Ubxn2b	UBX domain protein 2B	34589	0.15
chr11_51777861_51778012	0.46	Sar1b	secretion associated Ras related GTPase 1B	14242	0.15
chr1_162862241_162862422	0.46	Fmo1	flavin containing monooxygenase 1	2362	0.27
chr10_19452656_19452840	0.46	Gm33104	predicted gene, 33104	33967	0.17
chr1_67208435_67208586	0.46	Gm15668	predicted gene 15668	40690	0.16
chr6_29571610_29572022	0.46	Tnpo3	transportin 3	297	0.87
chr5_3554493_3554644	0.46	Fam133b	family with sequence similarity 133, member B	5094	0.1
chr12_72476829_72477076	0.45	Lrrc9	leucine rich repeat containing 9	878	0.43
chr16_77405236_77405411	0.45	Gm21816	predicted gene, 21816	4476	0.13
chr11_16883025_16883203	0.45	Egfr	epidermal growth factor receptor	4964	0.23
chr4_122960236_122960415	0.45	Mfsd2a	major facilitator superfamily domain containing 2A	335	0.76
chr10_4781737_4781912	0.45	Esr1	estrogen receptor 1 (alpha)	69173	0.13
chr8_108895943_108896094	0.45	Gm20686	predicted gene 20686	25856	0.18
chr13_96673388_96673576	0.45	Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	2546	0.22
chr1_162891657_162891835	0.45	Fmo2	flavin containing monooxygenase 2	5231	0.19
chr2_58773576_58773851	0.45	Upp2	uridine phosphorylase 2	8388	0.21
chr15_25715533_25715684	0.45	Myo10	myosin X	1737	0.4
chr4_95809182_95809353	0.45	Fggy	FGGY carbohydrate kinase domain containing	12711	0.27
chr3_145775927_145776137	0.44	Ddah1	dimethylarginine dimethylaminohydrolase 1	15284	0.2
chr5_30185873_30186127	0.44	Hadhb	hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta	5768	0.13
chr2_77155937_77156088	0.44	Ccdc141	coiled-coil domain containing 141	14564	0.21
chr3_79341737_79342019	0.44	Gm17359	predicted gene, 17359	3498	0.27
chr7_70514791_70515356	0.44	Gm44811	predicted gene 44811	16149	0.13
chr14_14070835_14071085	0.44	Atxn7	ataxin 7	16509	0.17
chr6_49217272_49217620	0.44	Igf2bp3	insulin-like growth factor 2 mRNA binding protein 3	2489	0.23
chr1_67200520_67200671	0.44	Gm15668	predicted gene 15668	48605	0.14
chr3_138263327_138263478	0.44	Adh1	alcohol dehydrogenase 1 (class I)	2411	0.19
chr12_32766682_32766844	0.44	Nampt	nicotinamide phosphoribosyltransferase	52782	0.12
chr1_75213471_75213622	0.44	Stk16	serine/threonine kinase 16	485	0.51
chr8_40903804_40903955	0.44	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	5441	0.18
chr18_75384388_75384763	0.44	Smad7	SMAD family member 7	9661	0.21
chr4_148616552_148616759	0.44	Tardbp	TAR DNA binding protein	325	0.81
chr14_21261451_21261651	0.44	Adk	adenosine kinase	56574	0.15
chr9_78290015_78290178	0.43	Gm10639	predicted gene 10639	168	0.9
chr17_88462554_88462727	0.43	Foxn2	forkhead box N2	21865	0.17
chr17_17375369_17375534	0.43	Riok2	RIO kinase 2	861	0.43
chr6_14787570_14787752	0.43	Ppp1r3a	protein phosphatase 1, regulatory subunit 3A	32387	0.24
chr4_6260711_6260862	0.43	Gm11798	predicted gene 11798	179	0.95
chr16_52417351_52417533	0.43	Alcam	activated leukocyte cell adhesion molecule	35023	0.23
chr5_96970232_96970383	0.43	Gm9484	predicted gene 9484	27057	0.09
chr17_12941646_12941826	0.43	Acat3	acetyl-Coenzyme A acetyltransferase 3	1136	0.27
chr7_115858420_115858571	0.43	Sox6	SRY (sex determining region Y)-box 6	1357	0.57
chr16_42908893_42909236	0.43	Zbtb20	zinc finger and BTB domain containing 20	1412	0.39
chr17_81174915_81175073	0.43	Gm50042	predicted gene, 50042	71744	0.11
chr14_31069071_31069222	0.43	Gm5459	predicted gene 5459	8289	0.1
chrX_170017951_170018104	0.42	Erdr1	erythroid differentiation regulator 1	7283	0.18
chr6_47814528_47814732	0.42	Rpl35a-ps7	ribosomal protein L35A, pseudogene 7	1002	0.31
chr16_34051044_34051195	0.42	Kalrn	kalirin, RhoGEF kinase	34625	0.16
chr15_78512853_78513047	0.42	C1qtnf6	C1q and tumor necrosis factor related protein 6	16642	0.09
chr1_172700535_172700739	0.42	Crp	C-reactive protein, pentraxin-related	2581	0.25
chr11_16843001_16843162	0.42	Egfros	epidermal growth factor receptor, opposite strand	12379	0.2
chr7_115733182_115733333	0.42	Sox6	SRY (sex determining region Y)-box 6	70892	0.13
chr11_107405500_107405698	0.42	Gm11713	predicted gene 11713	4791	0.15
chr8_114151087_114151399	0.41	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	17601	0.25

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Prop1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3	0.9	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	1.4	GO:0006526	arginine biosynthetic process(GO:0006526)
0.2	0.6	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.2	0.6	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2	0.5	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.2	0.5	GO:0097167	circadian regulation of translation(GO:0097167)
0.1	0.8	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.4	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.1	0.5	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.5	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.3	GO:0010963	regulation of L-arginine import(GO:0010963)
0.1	0.3	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1	0.4	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.1	0.3	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.4	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	1.0	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.2	GO:0072061	inner medullary collecting duct development(GO:0072061)
0.1	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.2	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1	0.2	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1	0.3	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.3	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.2	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.1	0.3	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.1	0.2	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1	0.2	GO:0032383	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1	0.2	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.2	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.1	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.1	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.1	0.2	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1	0.4	GO:0042977	activation of JAK2 kinase activity(GO:0042977)
0.1	0.2	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1	0.4	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.1	0.2	GO:0051684	maintenance of Golgi location(GO:0051684)
0.1	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.1	0.2	GO:0018879	biphenyl metabolic process(GO:0018879)
0.1	0.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.4	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.2	GO:0016554	cytidine to uridine editing(GO:0016554)
0.1	0.3	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.1	0.2	GO:0006177	GMP biosynthetic process(GO:0006177)
0.1	0.2	GO:0048478	replication fork protection(GO:0048478)
0.0	0.2	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.2	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.2	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.2	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.3	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:1904380	endoplasmic reticulum mannose trimming(GO:1904380)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.3	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.2	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.1	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0	0.1	GO:1902023	L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.2	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.2	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.2	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.1	GO:2000324	positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0	0.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.2	GO:0060017	parathyroid gland development(GO:0060017)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.1	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.1	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.3	GO:0000463	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0	0.1	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.1	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.0	0.1	GO:0046149	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.3	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.4	GO:0060856	establishment of blood-brain barrier(GO:0060856)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.3	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.2	GO:0007252	I-kappaB phosphorylation(GO:0007252)
0.0	0.2	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.1	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.2	GO:0019441	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:2000780	negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0	0.9	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0042373	vitamin K metabolic process(GO:0042373)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.5	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.0	0.3	GO:0048304	positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.0	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.1	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.3	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.2	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.1	GO:0071280	cellular response to copper ion(GO:0071280)
0.0	0.1	GO:0072093	metanephric renal vesicle formation(GO:0072093)
0.0	0.1	GO:0009169	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.1	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.2	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:0090148	membrane fission(GO:0090148)
0.0	0.4	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0009074	aromatic amino acid family catabolic process(GO:0009074)
0.0	0.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.6	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.2	GO:0015074	DNA integration(GO:0015074)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.3	GO:0001780	neutrophil homeostasis(GO:0001780)
0.0	0.3	GO:0007398	ectoderm development(GO:0007398)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.3	GO:0006743	ubiquinone metabolic process(GO:0006743)
0.0	0.3	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.1	GO:0008228	opsonization(GO:0008228)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.0	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.0	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.0	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0	0.1	GO:1903999	negative regulation of eating behavior(GO:1903999)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.0	GO:0000720	pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0	0.1	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0009173	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.6	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.0	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.6	GO:0019432	triglyceride biosynthetic process(GO:0019432)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.1	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.2	GO:0071044	histone mRNA catabolic process(GO:0071044)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.0	GO:1903984	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.0	GO:0032621	interleukin-18 production(GO:0032621)
0.0	0.1	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.3	GO:0051923	sulfation(GO:0051923)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.2	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.1	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0	0.0	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.1	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.3	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.0	GO:0051142	regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0014854	response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0	0.0	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0019896	axonal transport of mitochondrion(GO:0019896)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.2	GO:0006388	tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.2	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0006901	vesicle coating(GO:0006901)
0.0	0.1	GO:0098870	neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0	0.1	GO:0045416	positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0	0.1	GO:0009435	NAD biosynthetic process(GO:0009435)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.2	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0060373	regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0	0.0	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0033563	dorsal/ventral axon guidance(GO:0033563)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	0.0	GO:0033092	positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.0	GO:0071688	skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.1	GO:0007135	meiosis II(GO:0007135)
0.0	0.0	GO:0072025	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.2	GO:0032958	inositol phosphate biosynthetic process(GO:0032958)
0.0	0.0	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.0	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.0	GO:0006570	tyrosine metabolic process(GO:0006570)
0.0	0.1	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.1	GO:0048852	diencephalon morphogenesis(GO:0048852)
0.0	0.0	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0006002	fructose 6-phosphate metabolic process(GO:0006002)
0.0	0.1	GO:0030311	poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0	0.0	GO:0002155	regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.0	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0	0.0	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0	0.1	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.3	GO:0045187	regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0	0.5	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.0	GO:0051657	maintenance of organelle location(GO:0051657)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.3	GO:0045070	positive regulation of viral genome replication(GO:0045070)
0.0	0.1	GO:0043985	histone H4-R3 methylation(GO:0043985)
0.0	0.1	GO:0006047	UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.0	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.1	GO:0045653	negative regulation of megakaryocyte differentiation(GO:0045653)
0.0	0.0	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.0	GO:0048677	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0	0.0	GO:0051561	positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0	0.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.0	GO:0000237	leptotene(GO:0000237)
0.0	0.1	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536)
0.0	0.0	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.3	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.0	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.0	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.0	GO:0009629	response to gravity(GO:0009629)
0.0	0.0	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.2	GO:0045986	negative regulation of smooth muscle contraction(GO:0045986)
0.0	0.0	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.2	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.0	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.1	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.3	GO:0031440	regulation of mRNA 3'-end processing(GO:0031440)
0.0	0.1	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.0	GO:0061724	lipophagy(GO:0061724)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.0	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.1	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.0	GO:0072488	ammonium transmembrane transport(GO:0072488)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0048548	regulation of pinocytosis(GO:0048548) positive regulation of pinocytosis(GO:0048549)
0.0	0.0	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.0	GO:1904192	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.1	GO:0046416	D-amino acid metabolic process(GO:0046416)
0.0	0.0	GO:0007468	regulation of rhodopsin gene expression(GO:0007468)
0.0	0.2	GO:1902230	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0	0.1	GO:0043116	negative regulation of vascular permeability(GO:0043116)
0.0	0.0	GO:0015755	fructose transport(GO:0015755)
0.0	0.0	GO:0030421	defecation(GO:0030421)
0.0	0.0	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.0	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0046831	regulation of RNA export from nucleus(GO:0046831)
0.0	0.0	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.0	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.0	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:0007597	blood coagulation, intrinsic pathway(GO:0007597)
0.0	0.0	GO:0098535	de novo centriole assembly(GO:0098535)
0.0	0.1	GO:0045198	establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0	0.0	GO:0032957	inositol trisphosphate metabolic process(GO:0032957)
0.0	0.2	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.1	GO:0015791	polyol transport(GO:0015791)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.2	GO:0060218	hematopoietic stem cell differentiation(GO:0060218)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.0	GO:0014721	voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0	0.1	GO:0048681	negative regulation of axon regeneration(GO:0048681)
0.0	0.0	GO:1902369	negative regulation of RNA catabolic process(GO:1902369)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.4	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	0.3	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.1	0.3	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.3	GO:0097454	Schwann cell microvillus(GO:0097454)
0.1	0.2	GO:0097413	Lewy body(GO:0097413)
0.1	0.8	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1	0.6	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.1	0.2	GO:0008091	spectrin(GO:0008091)
0.1	0.2	GO:0070939	Dsl1p complex(GO:0070939)
0.1	0.2	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.2	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.5	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.7	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.2	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0002177	manchette(GO:0002177)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.2	GO:0016589	NURF complex(GO:0016589)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0005608	laminin-3 complex(GO:0005608)
0.0	0.5	GO:0030134	ER to Golgi transport vesicle(GO:0030134)
0.0	0.2	GO:0005687	U4 snRNP(GO:0005687)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.2	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.0	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0045293	mRNA editing complex(GO:0045293)
0.0	0.3	GO:0001527	microfibril(GO:0001527)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.0	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.3	GO:0031430	M band(GO:0031430)
0.0	0.1	GO:0031010	ISWI-type complex(GO:0031010)
0.0	0.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0000813	ESCRT I complex(GO:0000813)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.2	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.0	GO:0005606	laminin-1 complex(GO:0005606)
0.0	0.0	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0034709	methylosome(GO:0034709)
0.0	0.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.2	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.2	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.0	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.0	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.1	GO:0005685	U1 snRNP(GO:0005685)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.0	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.0	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.6	GO:0005811	lipid particle(GO:0005811)
0.0	0.2	GO:0000242	pericentriolar material(GO:0000242)
0.0	0.1	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.5	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.3	GO:0008023	transcription elongation factor complex(GO:0008023)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.3	GO:0048786	presynaptic active zone(GO:0048786)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.7	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.4	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.9	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.3	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1	0.3	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.4	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.1	0.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.6	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.1	0.4	GO:0003680	AT DNA binding(GO:0003680)
0.1	0.2	GO:0030621	U4 snRNA binding(GO:0030621)
0.1	0.2	GO:0050692	DBD domain binding(GO:0050692)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0052724	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1	0.6	GO:0051787	misfolded protein binding(GO:0051787)
0.1	0.3	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.1	0.2	GO:0070573	metallodipeptidase activity(GO:0070573)
0.1	0.2	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.3	GO:0034875	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.3	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.3	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.2	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.4	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.1	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.0	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.5	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.3	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.4	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.4	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	1.0	GO:0052768	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0008430	selenium binding(GO:0008430)
0.0	0.9	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.2	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.2	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0004090	carbonyl reductase (NADPH) activity(GO:0004090)
0.0	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.7	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.0	GO:0004723	calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.1	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.6	GO:0015347	sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.0	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0000339	RNA cap binding(GO:0000339)
0.0	0.4	GO:0015924	mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0046974	histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0	0.1	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0003846	2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0	0.2	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0070324	thyroid hormone binding(GO:0070324)
0.0	0.1	GO:0008121	ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0	0.1	GO:0016884	carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.2	GO:0045236	CXCR chemokine receptor binding(GO:0045236)
0.0	0.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.3	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.2	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.0	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.4	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.2	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.0	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:2001069	glycogen binding(GO:2001069)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)
0.0	0.1	GO:0044020	histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0061505	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.0	GO:0010861	thyroid hormone receptor activator activity(GO:0010861)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0043559	insulin binding(GO:0043559)
0.0	0.1	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.0	GO:0000702	oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)
0.0	0.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.2	GO:0030506	ankyrin binding(GO:0030506)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.0	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)
0.0	0.0	GO:0003923	GPI-anchor transamidase activity(GO:0003923)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0034951	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.3	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.0	GO:0016303	1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0052760	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.1	PID IL6 7 PATHWAY	IL6-mediated signaling events
0.0	0.2	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.6	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.1	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.0	1.0	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.5	ST MYOCYTE AD PATHWAY	Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0	0.2	SA PTEN PATHWAY	PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0	1.0	PID ERA GENOMIC PATHWAY	Validated nuclear estrogen receptor alpha network
0.0	0.3	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.0	0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.3	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.1	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.4	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.1	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	0.4	PID BMP PATHWAY	BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0	Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1	0.8	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.8	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.4	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.5	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.0	REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G	Genes involved in Vif-mediated degradation of APOBEC3G
0.0	0.0	REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1	Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0	0.3	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.3	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.3	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.4	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.1	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.3	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.2	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.2	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.3	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.3	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.4	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.5	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.6	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.1	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME PROSTANOID LIGAND RECEPTORS	Genes involved in Prostanoid ligand receptors
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.2	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.2	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.3	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.0	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	2.3	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.2	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.1	REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX	Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0	0.2	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.2	REACTOME NUCLEAR SIGNALING BY ERBB4	Genes involved in Nuclear signaling by ERBB4
0.0	0.1	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.2	REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION	Genes involved in Transport to the Golgi and subsequent modification

Results for Prop1

Z-value: 1.29

Motif logo

Transcription factors associated with Prop1

Activity of the Prop1 motif across conditions

Conditions sorted by the z-value of the Prop1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Prop1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: