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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Prop1

Z-value: 1.29

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Transcription factors associated with Prop1

Gene Symbol Gene ID Gene Info
ENSMUSG00000044542.3 Prop1

Activity of the Prop1 motif across conditions

Conditions sorted by the z-value of the Prop1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr10_124590350_124590536 1.85 4930503E24Rik
RIKEN cDNA 4930503E24 gene
67005
0.14
chr10_87040962_87041138 1.46 1700113H08Rik
RIKEN cDNA 1700113H08 gene
16995
0.16
chr16_43169836_43170008 1.26 Gm15712
predicted gene 15712
14651
0.21
chr17_79018863_79019084 1.18 Prkd3
protein kinase D3
1804
0.3
chr19_12613616_12613767 1.12 Gm4952
predicted gene 4952
13675
0.09
chr5_86919547_86919811 1.12 Gm25211
predicted gene, 25211
3357
0.13
chr8_110644559_110644860 1.11 Vac14
Vac14 homolog (S. cerevisiae)
871
0.63
chr17_80022007_80022158 0.99 Gm22215
predicted gene, 22215
11432
0.14
chr9_74672657_74672818 0.98 Gm27233
predicted gene 27233
36525
0.18
chr8_76152735_76152886 0.98 Gm45742
predicted gene 45742
35783
0.19
chr6_24610042_24610446 0.97 Lmod2
leiomodin 2 (cardiac)
12482
0.14
chr1_100298746_100298897 0.95 Gm29667
predicted gene 29667
16030
0.18
chr16_79086922_79087073 0.94 Tmprss15
transmembrane protease, serine 15
4095
0.35
chr7_97411671_97412103 0.93 Thrsp
thyroid hormone responsive
5632
0.13
chr3_95879412_95879563 0.92 Ciart
circadian associated repressor of transcription
1759
0.16
chr9_74885383_74885534 0.91 Onecut1
one cut domain, family member 1
18974
0.14
chr4_76942367_76942518 0.90 Gm11246
predicted gene 11246
15131
0.21
chr4_47366562_47366857 0.90 Tgfbr1
transforming growth factor, beta receptor I
13099
0.22
chr1_140421414_140421565 0.85 Kcnt2
potassium channel, subfamily T, member 2
21447
0.27
chr10_87868820_87868971 0.85 Igf1os
insulin-like growth factor 1, opposite strand
5514
0.22
chr1_21259850_21260251 0.85 Gsta3
glutathione S-transferase, alpha 3
6529
0.11
chr3_76637152_76637321 0.84 Fstl5
follistatin-like 5
43686
0.19
chr5_100369426_100369577 0.83 Sec31a
Sec31 homolog A (S. cerevisiae)
3983
0.2
chr15_38049613_38049764 0.83 Gm22353
predicted gene, 22353
8597
0.16
chr8_109981175_109981347 0.82 Gm45795
predicted gene 45795
6909
0.13
chr10_4617695_4617851 0.81 Esr1
estrogen receptor 1 (alpha)
5752
0.25
chr13_115653702_115653853 0.80 Gm47892
predicted gene, 47892
65722
0.13
chr12_51274477_51274668 0.79 Rps11-ps4
ribosomal protein S11, pseudogene 4
22915
0.22
chrX_49489499_49489695 0.79 Arhgap36
Rho GTPase activating protein 36
3922
0.27
chr4_121078016_121078199 0.79 Zmpste24
zinc metallopeptidase, STE24
369
0.74
chr9_74881714_74881880 0.78 Onecut1
one cut domain, family member 1
15313
0.15
chr2_18435403_18435565 0.77 Dnajc1
DnaJ heat shock protein family (Hsp40) member C1
42654
0.16
chr2_64059065_64059258 0.77 Fign
fidgetin
38827
0.23
chr10_87936931_87937082 0.76 Tyms-ps
thymidylate synthase, pseudogene
29841
0.15
chr4_101198122_101198415 0.74 Gm24468
predicted gene, 24468
11504
0.14
chr12_105824675_105824843 0.74 Papola
poly (A) polymerase alpha
4308
0.21
chr2_121507198_121507349 0.72 Wdr76
WD repeat domain 76
490
0.46
chr2_177468355_177468573 0.72 Zfp970
zinc finger protein 970
3618
0.19
chr5_87589802_87589979 0.72 Sult1e1
sulfotransferase family 1E, member 1
1704
0.22
chr2_38823684_38823849 0.72 Nr6a1os
nuclear receptor subfamily 6, group A, member 1, opposite strand
425
0.74
chr2_31499430_31499808 0.71 Ass1
argininosuccinate synthetase 1
1107
0.5
chr2_31519719_31520357 0.69 Ass1
argininosuccinate synthetase 1
1548
0.36
chr1_124069161_124069328 0.69 Dpp10
dipeptidylpeptidase 10
23685
0.27
chr18_53860444_53860644 0.68 Csnk1g3
casein kinase 1, gamma 3
1578
0.52
chr8_76147788_76147939 0.68 Gm45742
predicted gene 45742
30836
0.21
chr5_90899182_90899382 0.68 Cxcl2
chemokine (C-X-C motif) ligand 2
4589
0.13
chr13_63113927_63114104 0.67 Aopep
aminopeptidase O
6493
0.16
chr9_106245058_106245282 0.66 Alas1
aminolevulinic acid synthase 1
1536
0.23
chr3_18137155_18137306 0.66 Gm23686
predicted gene, 23686
40395
0.15
chr3_144109828_144110050 0.66 Gm34078
predicted gene, 34078
25815
0.2
chr8_93245968_93246147 0.66 Gm45727
predicted gene 45727
5118
0.15
chr10_87032560_87032752 0.65 Stab2
stabilin 2
24631
0.14
chr4_90082681_90082858 0.65 Gm12629
predicted gene 12629
102758
0.08
chr2_53178520_53178671 0.64 Prpf40a
pre-mRNA processing factor 40A
11505
0.23
chr11_16888258_16888409 0.64 Egfr
epidermal growth factor receptor
10183
0.2
chr10_93196295_93196461 0.64 Cdk17
cyclin-dependent kinase 17
10609
0.2
chr6_146271566_146271772 0.64 Gm44086
predicted gene, 44086
689
0.74
chr11_120238015_120238347 0.63 Bahcc1
BAH domain and coiled-coil containing 1
1482
0.22
chr6_122571659_122571823 0.63 Gm16556
predicted gene 16556
892
0.4
chr2_77543027_77543190 0.63 Zfp385b
zinc finger protein 385B
18872
0.25
chr3_60099135_60099299 0.63 Sucnr1
succinate receptor 1
17315
0.18
chr13_69640079_69640317 0.62 Nsun2
NOL1/NOP2/Sun domain family member 2
9458
0.1
chr8_104787437_104787637 0.62 Gm45782
predicted gene 45782
1709
0.21
chr14_34316954_34317105 0.62 Glud1
glutamate dehydrogenase 1
6302
0.11
chr8_93183570_93183871 0.62 Gm45909
predicted gene 45909
7638
0.14
chr11_28696253_28696446 0.61 2810471M01Rik
RIKEN cDNA 2810471M01 gene
14785
0.17
chr9_24922429_24922589 0.61 Gm48255
predicted gene, 48255
30464
0.13
chr2_134708873_134709037 0.61 Gm14037
predicted gene 14037
22152
0.2
chr1_67150788_67150939 0.61 Cps1
carbamoyl-phosphate synthetase 1
27837
0.2
chr5_99976807_99976958 0.61 Hnrnpd
heterogeneous nuclear ribonucleoprotein D
331
0.73
chr4_148615928_148616079 0.61 Tardbp
TAR DNA binding protein
135
0.93
chr2_65212598_65212873 0.60 Cobll1
Cobl-like 1
23260
0.17
chr6_71999696_71999905 0.60 Gm26628
predicted gene, 26628
36025
0.1
chr9_109966945_109967106 0.60 Map4
microtubule-associated protein 4
1992
0.21
chr3_94710144_94710297 0.60 Selenbp2
selenium binding protein 2
16561
0.1
chr11_16834846_16835011 0.59 Egfros
epidermal growth factor receptor, opposite strand
4226
0.25
chr1_67222842_67222998 0.59 Gm15668
predicted gene 15668
26280
0.19
chr6_119681087_119681251 0.59 Erc1
ELKS/RAB6-interacting/CAST family member 1
59064
0.13
chr16_26702287_26702472 0.59 Il1rap
interleukin 1 receptor accessory protein
20055
0.24
chr3_94717786_94717937 0.58 Gm43711
predicted gene 43711
19482
0.1
chr5_72948525_72948751 0.58 Slain2
SLAIN motif family, member 2
139
0.94
chrX_109145684_109145835 0.57 Gm14869
predicted gene 14869
24075
0.17
chr11_16798476_16798627 0.57 Egfros
epidermal growth factor receptor, opposite strand
32151
0.16
chr19_37507552_37507703 0.57 Exoc6
exocyst complex component 6
13252
0.16
chr5_33465811_33466048 0.57 Gm43851
predicted gene 43851
28465
0.15
chr7_67658992_67659201 0.57 Ttc23
tetratricopeptide repeat domain 23
3649
0.17
chr2_141998050_141998201 0.57 Fau-ps1
Finkel-Biskis-Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived), pseudogene 1
159336
0.04
chr16_43234125_43234650 0.57 Zbtb20
zinc finger and BTB domain containing 20
1493
0.45
chr6_100267052_100267222 0.56 Gm44044
predicted gene, 44044
6561
0.17
chr18_75498893_75499229 0.56 Gm10532
predicted gene 10532
15584
0.25
chr2_8123996_8124147 0.55 Gm13254
predicted gene 13254
23794
0.29
chr6_55171107_55171477 0.55 Inmt
indolethylamine N-methyltransferase
3722
0.2
chr8_93235526_93235686 0.55 Ces1e
carboxylesterase 1E
5987
0.14
chr3_133725023_133725174 0.55 Gm40153
predicted gene, 40153
61707
0.1
chr9_55277952_55278103 0.55 Nrg4
neuregulin 4
5545
0.2
chr4_151043729_151043930 0.55 Per3
period circadian clock 3
836
0.56
chr6_108454056_108454259 0.55 Itpr1
inositol 1,4,5-trisphosphate receptor 1
4546
0.21
chr13_112500544_112500748 0.54 Il6st
interleukin 6 signal transducer
25600
0.14
chrX_61144273_61144442 0.54 Gm24396
predicted gene, 24396
1005
0.5
chr1_162891903_162892071 0.54 Fmo2
flavin containing monooxygenase 2
5472
0.19
chr2_146546861_146547083 0.54 4933406D12Rik
RIKEN cDNA 4933406D12 gene
4041
0.3
chr19_14226869_14227031 0.54 Gm26993
predicted gene, 26993
208579
0.02
chr16_37873974_37874125 0.54 Lrrc58
leucine rich repeat containing 58
5660
0.14
chr14_47294893_47295081 0.54 Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
3279
0.11
chr6_50561677_50561828 0.53 Cycs
cytochrome c, somatic
4197
0.12
chr1_160280517_160280905 0.53 Rabgap1l
RAB GTPase activating protein 1-like
6627
0.14
chr13_42723821_42724025 0.53 Phactr1
phosphatase and actin regulator 1
14342
0.24
chr1_4829620_4829787 0.53 Lypla1
lysophospholipase 1
7202
0.13
chr5_130227356_130227532 0.53 Gm42467
predicted gene 42467
1228
0.28
chr16_6366127_6366312 0.53 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
17081
0.31
chr5_52147484_52147676 0.53 Gm43176
predicted gene 43176
5007
0.13
chr17_89653592_89653743 0.53 Gm50061
predicted gene, 50061
98859
0.09
chr2_84379041_84379217 0.52 Calcrl
calcitonin receptor-like
3771
0.25
chr19_12652059_12652547 0.52 Glyat
glycine-N-acyltransferase
12811
0.09
chr15_38105734_38106027 0.52 Gm49312
predicted gene, 49312
26778
0.13
chr1_21242443_21242594 0.51 Gsta3
glutathione S-transferase, alpha 3
1889
0.22
chr8_109995374_109995556 0.51 Tat
tyrosine aminotransferase
4959
0.13
chr18_42685880_42686031 0.51 C030004G16Rik
RIKEN cDNA C030004G16 gene
63496
0.1
chr1_67169083_67169234 0.51 Cps1
carbamoyl-phosphate synthetase 1
46132
0.15
chr10_86690190_86690443 0.51 Gm15344
predicted gene 15344
2779
0.1
chr9_44940562_44940729 0.51 Gm19121
predicted gene, 19121
15070
0.08
chr10_87921071_87921222 0.51 Tyms-ps
thymidylate synthase, pseudogene
45701
0.12
chr5_90364825_90365036 0.50 Ankrd17
ankyrin repeat domain 17
1255
0.37
chr3_158035265_158035416 0.50 Gm43362
predicted gene 43362
1069
0.28
chr15_58983651_58983950 0.50 4930544F09Rik
RIKEN cDNA 4930544F09 gene
336
0.87
chr17_64676171_64676533 0.50 Man2a1
mannosidase 2, alpha 1
37068
0.18
chr7_100610040_100610203 0.50 Mrpl48
mitochondrial ribosomal protein L48
1820
0.19
chr2_84996201_84996436 0.49 Prg3
proteoglycan 3
8103
0.12
chr8_5099240_5099445 0.49 Slc10a2
solute carrier family 10, member 2
6009
0.18
chrY_90792564_90792728 0.49 Gm47283
predicted gene, 47283
2195
0.29
chr6_17478662_17478867 0.49 Met
met proto-oncogene
12477
0.21
chr4_100290333_100290484 0.49 Gm12706
predicted gene 12706
71651
0.11
chr2_146325477_146325645 0.49 Gm14117
predicted gene 14117
20014
0.21
chr5_107123329_107123511 0.49 Tgfbr3
transforming growth factor, beta receptor III
9503
0.17
chr18_85490238_85490398 0.49 Gm7612
predicted gene 7612
226407
0.02
chr5_151246921_151247115 0.48 5430435K18Rik
RIKEN cDNA 5430435K18 gene
5287
0.21
chr5_150270318_150270506 0.48 Fry
FRY microtubule binding protein
10645
0.18
chr2_75698638_75698789 0.48 Nfe2l2
nuclear factor, erythroid derived 2, like 2
5776
0.13
chr8_93165469_93165620 0.48 Ces1d
carboxylesterase 1D
4431
0.16
chr11_38774641_38774792 0.48 Gm23520
predicted gene, 23520
23561
0.29
chr4_108060521_108060686 0.47 Scp2
sterol carrier protein 2, liver
10760
0.13
chr4_121164131_121164282 0.47 Rlf
rearranged L-myc fusion sequence
24328
0.11
chrY_90800880_90801048 0.47 Gm47283
predicted gene, 47283
10513
0.18
chr10_69208679_69208830 0.47 Rhobtb1
Rho-related BTB domain containing 1
202
0.94
chr19_39287276_39287531 0.47 Cyp2c29
cytochrome P450, family 2, subfamily c, polypeptide 29
329
0.91
chr1_60098880_60099160 0.47 Wdr12
WD repeat domain 12
375
0.68
chr4_6225587_6225787 0.46 Ubxn2b
UBX domain protein 2B
34589
0.15
chr11_51777861_51778012 0.46 Sar1b
secretion associated Ras related GTPase 1B
14242
0.15
chr1_162862241_162862422 0.46 Fmo1
flavin containing monooxygenase 1
2362
0.27
chr10_19452656_19452840 0.46 Gm33104
predicted gene, 33104
33967
0.17
chr1_67208435_67208586 0.46 Gm15668
predicted gene 15668
40690
0.16
chr6_29571610_29572022 0.46 Tnpo3
transportin 3
297
0.87
chr5_3554493_3554644 0.46 Fam133b
family with sequence similarity 133, member B
5094
0.1
chr12_72476829_72477076 0.45 Lrrc9
leucine rich repeat containing 9
878
0.43
chr16_77405236_77405411 0.45 Gm21816
predicted gene, 21816
4476
0.13
chr11_16883025_16883203 0.45 Egfr
epidermal growth factor receptor
4964
0.23
chr4_122960236_122960415 0.45 Mfsd2a
major facilitator superfamily domain containing 2A
335
0.76
chr10_4781737_4781912 0.45 Esr1
estrogen receptor 1 (alpha)
69173
0.13
chr8_108895943_108896094 0.45 Gm20686
predicted gene 20686
25856
0.18
chr13_96673388_96673576 0.45 Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
2546
0.22
chr1_162891657_162891835 0.45 Fmo2
flavin containing monooxygenase 2
5231
0.19
chr2_58773576_58773851 0.45 Upp2
uridine phosphorylase 2
8388
0.21
chr15_25715533_25715684 0.45 Myo10
myosin X
1737
0.4
chr4_95809182_95809353 0.45 Fggy
FGGY carbohydrate kinase domain containing
12711
0.27
chr3_145775927_145776137 0.44 Ddah1
dimethylarginine dimethylaminohydrolase 1
15284
0.2
chr5_30185873_30186127 0.44 Hadhb
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta
5768
0.13
chr2_77155937_77156088 0.44 Ccdc141
coiled-coil domain containing 141
14564
0.21
chr3_79341737_79342019 0.44 Gm17359
predicted gene, 17359
3498
0.27
chr7_70514791_70515356 0.44 Gm44811
predicted gene 44811
16149
0.13
chr14_14070835_14071085 0.44 Atxn7
ataxin 7
16509
0.17
chr6_49217272_49217620 0.44 Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
2489
0.23
chr1_67200520_67200671 0.44 Gm15668
predicted gene 15668
48605
0.14
chr3_138263327_138263478 0.44 Adh1
alcohol dehydrogenase 1 (class I)
2411
0.19
chr12_32766682_32766844 0.44 Nampt
nicotinamide phosphoribosyltransferase
52782
0.12
chr1_75213471_75213622 0.44 Stk16
serine/threonine kinase 16
485
0.51
chr8_40903804_40903955 0.44 Slc7a2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
5441
0.18
chr18_75384388_75384763 0.44 Smad7
SMAD family member 7
9661
0.21
chr4_148616552_148616759 0.44 Tardbp
TAR DNA binding protein
325
0.81
chr14_21261451_21261651 0.44 Adk
adenosine kinase
56574
0.15
chr9_78290015_78290178 0.43 Gm10639
predicted gene 10639
168
0.9
chr17_88462554_88462727 0.43 Foxn2
forkhead box N2
21865
0.17
chr17_17375369_17375534 0.43 Riok2
RIO kinase 2
861
0.43
chr6_14787570_14787752 0.43 Ppp1r3a
protein phosphatase 1, regulatory subunit 3A
32387
0.24
chr4_6260711_6260862 0.43 Gm11798
predicted gene 11798
179
0.95
chr16_52417351_52417533 0.43 Alcam
activated leukocyte cell adhesion molecule
35023
0.23
chr5_96970232_96970383 0.43 Gm9484
predicted gene 9484
27057
0.09
chr17_12941646_12941826 0.43 Acat3
acetyl-Coenzyme A acetyltransferase 3
1136
0.27
chr7_115858420_115858571 0.43 Sox6
SRY (sex determining region Y)-box 6
1357
0.57
chr16_42908893_42909236 0.43 Zbtb20
zinc finger and BTB domain containing 20
1412
0.39
chr17_81174915_81175073 0.43 Gm50042
predicted gene, 50042
71744
0.11
chr14_31069071_31069222 0.43 Gm5459
predicted gene 5459
8289
0.1
chrX_170017951_170018104 0.42 Erdr1
erythroid differentiation regulator 1
7283
0.18
chr6_47814528_47814732 0.42 Rpl35a-ps7
ribosomal protein L35A, pseudogene 7
1002
0.31
chr16_34051044_34051195 0.42 Kalrn
kalirin, RhoGEF kinase
34625
0.16
chr15_78512853_78513047 0.42 C1qtnf6
C1q and tumor necrosis factor related protein 6
16642
0.09
chr1_172700535_172700739 0.42 Crp
C-reactive protein, pentraxin-related
2581
0.25
chr11_16843001_16843162 0.42 Egfros
epidermal growth factor receptor, opposite strand
12379
0.2
chr7_115733182_115733333 0.42 Sox6
SRY (sex determining region Y)-box 6
70892
0.13
chr11_107405500_107405698 0.42 Gm11713
predicted gene 11713
4791
0.15
chr8_114151087_114151399 0.41 Nudt7
nudix (nucleoside diphosphate linked moiety X)-type motif 7
17601
0.25

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Prop1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.3 0.9 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.2 1.4 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 0.6 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.2 0.6 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.2 0.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.2 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.4 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.5 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.5 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.3 GO:0010963 regulation of L-arginine import(GO:0010963)
0.1 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1 0.4 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.1 0.3 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.5 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 0.4 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.1 1.0 GO:0009404 toxin metabolic process(GO:0009404)
0.1 0.2 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.1 0.2 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.2 GO:2000302 positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.1 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.1 0.2 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 0.2 GO:0032383 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.1 0.2 GO:0039689 negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.2 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.1 0.1 GO:0034310 primary alcohol catabolic process(GO:0034310)
0.1 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.1 0.2 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.4 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.1 0.2 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.4 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.1 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.2 GO:0018879 biphenyl metabolic process(GO:0018879)
0.1 0.2 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.1 0.4 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.1 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.2 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:1903334 positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.1 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0035696 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)
0.0 0.1 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.2 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:2000324 positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.1 GO:1900045 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 0.1 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.3 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.1 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0 0.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.1 GO:0046149 heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.3 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.4 GO:0060856 establishment of blood-brain barrier(GO:0060856)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.3 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0075509 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0 0.1 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:2000780 negative regulation of DNA repair(GO:0045738) negative regulation of double-strand break repair(GO:2000780)
0.0 0.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.0 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.5 GO:0031116 positive regulation of microtubule polymerization(GO:0031116)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.3 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.1 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.1 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.0 0.1 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.0 0.3 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.1 GO:0071280 cellular response to copper ion(GO:0071280)
0.0 0.1 GO:0072093 metanephric renal vesicle formation(GO:0072093)
0.0 0.1 GO:0009169 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.1 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.2 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.1 GO:0090148 membrane fission(GO:0090148)
0.0 0.4 GO:0009109 coenzyme catabolic process(GO:0009109)
0.0 0.0 GO:0009074 aromatic amino acid family catabolic process(GO:0009074)
0.0 0.1 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.6 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.2 GO:0015074 DNA integration(GO:0015074)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.3 GO:0006743 ubiquinone metabolic process(GO:0006743)
0.0 0.3 GO:0008105 asymmetric protein localization(GO:0008105)
0.0 0.1 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.0 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.0 GO:1902730 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.1 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0061370 testosterone biosynthetic process(GO:0061370)
0.0 0.0 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.0 0.1 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.6 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.0 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0048143 astrocyte activation(GO:0048143)
0.0 0.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.2 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.0 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0015871 choline transport(GO:0015871)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:0032621 interleukin-18 production(GO:0032621)
0.0 0.1 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.3 GO:0051923 sulfation(GO:0051923)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.0 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.0 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.0 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0014854 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.0 GO:0070827 chromatin maintenance(GO:0070827)
0.0 0.1 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.1 GO:1902075 cellular response to salt(GO:1902075)
0.0 0.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0019896 axonal transport of mitochondrion(GO:0019896)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.1 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0 0.0 GO:0006901 vesicle coating(GO:0006901)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0045416 positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.1 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.0 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.1 GO:0060373 regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373)
0.0 0.0 GO:0014873 response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0 0.1 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.0 GO:0038095 Fc-epsilon receptor signaling pathway(GO:0038095)
0.0 0.0 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.0 GO:0071688 skeletal muscle myosin thick filament assembly(GO:0030241) striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0007135 meiosis II(GO:0007135)
0.0 0.0 GO:0072025 distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0 0.2 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.0 0.0 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.0 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 0.0 GO:0006570 tyrosine metabolic process(GO:0006570)
0.0 0.1 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.1 GO:0048852 diencephalon morphogenesis(GO:0048852)
0.0 0.0 GO:0071455 cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0 0.1 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.0 0.0 GO:0002155 regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0 0.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.0 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0 0.0 GO:1903238 positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0 0.1 GO:0060431 primary lung bud formation(GO:0060431)
0.0 0.3 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.5 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.0 GO:0051657 maintenance of organelle location(GO:0051657)
0.0 0.0 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.3 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.1 GO:0006047 UDP-N-acetylglucosamine metabolic process(GO:0006047)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0090188 negative regulation of pancreatic juice secretion(GO:0090188)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.0 GO:0046655 folic acid metabolic process(GO:0046655)
0.0 0.0 GO:0010519 negative regulation of phospholipase activity(GO:0010519)
0.0 0.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.0 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 0.0 GO:0000237 leptotene(GO:0000237)
0.0 0.1 GO:0002536 respiratory burst involved in inflammatory response(GO:0002536)
0.0 0.0 GO:0048550 negative regulation of pinocytosis(GO:0048550)
0.0 0.1 GO:0032060 bleb assembly(GO:0032060)
0.0 0.0 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0071033 nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:0009629 response to gravity(GO:0009629)
0.0 0.0 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0045986 negative regulation of smooth muscle contraction(GO:0045986)
0.0 0.0 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.2 GO:0014733 regulation of skeletal muscle adaptation(GO:0014733)
0.0 0.0 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.0 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:1904293 negative regulation of ERAD pathway(GO:1904293)
0.0 0.0 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:0031440 regulation of mRNA 3'-end processing(GO:0031440)
0.0 0.1 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.0 GO:0061724 lipophagy(GO:0061724)
0.0 0.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.0 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.0 0.0 GO:2000054 negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.0 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0048548 regulation of pinocytosis(GO:0048548) positive regulation of pinocytosis(GO:0048549)
0.0 0.0 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.0 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0006590 thyroid hormone generation(GO:0006590)
0.0 0.0 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0046416 D-amino acid metabolic process(GO:0046416)
0.0 0.0 GO:0007468 regulation of rhodopsin gene expression(GO:0007468)
0.0 0.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.1 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.0 GO:0015755 fructose transport(GO:0015755)
0.0 0.0 GO:0030421 defecation(GO:0030421)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:1904684 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.1 GO:0046831 regulation of RNA export from nucleus(GO:0046831)
0.0 0.0 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.0 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.0 GO:0098535 de novo centriole assembly(GO:0098535)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.0 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.0 0.2 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 0.1 GO:0015791 polyol transport(GO:0015791)
0.0 0.0 GO:0072131 kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0 0.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.0 GO:0051665 membrane raft localization(GO:0051665)
0.0 0.0 GO:0014721 voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.1 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.0 GO:1902369 negative regulation of RNA catabolic process(GO:1902369)
0.0 0.1 GO:0035457 cellular response to interferon-alpha(GO:0035457)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.4 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.3 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.3 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.2 GO:0097413 Lewy body(GO:0097413)
0.1 0.8 GO:0070852 cell body fiber(GO:0070852)
0.1 0.4 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.6 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 0.2 GO:0008091 spectrin(GO:0008091)
0.1 0.2 GO:0070939 Dsl1p complex(GO:0070939)
0.1 0.2 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.7 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.3 GO:0016342 catenin complex(GO:0016342)
0.0 0.1 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.0 0.2 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0045293 mRNA editing complex(GO:0045293)
0.0 0.3 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.0 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.9 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.2 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0031430 M band(GO:0031430)
0.0 0.1 GO:0031010 ISWI-type complex(GO:0031010)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.0 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.0 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.1 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.2 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.0 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.1 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.1 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.0 GO:0009279 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.0 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.1 GO:0005685 U1 snRNP(GO:0005685)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.0 GO:1903349 omegasome membrane(GO:1903349)
0.0 0.2 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.0 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.6 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.5 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.3 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.2 0.7 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0009374 biotin binding(GO:0009374)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.2 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.1 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 0.3 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.6 GO:0051787 misfolded protein binding(GO:0051787)
0.1 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 0.2 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0034875 oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0 0.3 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.5 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.3 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0031782 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.2 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 1.0 GO:0052768 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.9 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0035671 enone reductase activity(GO:0035671)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.7 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.0 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.0 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.1 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.6 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.0 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.4 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.4 GO:0015924 mannosyl-oligosaccharide mannosidase activity(GO:0015924)
0.0 0.1 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.0 0.1 GO:0005167 neurotrophin TRK receptor binding(GO:0005167)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.1 GO:0019976 interleukin-2 binding(GO:0019976)
0.0 0.1 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0016884 carbon-nitrogen ligase activity, with glutamine as amido-N-donor(GO:0016884)
0.0 0.0 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.0 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.0 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.0 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.0 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0000104 succinate dehydrogenase activity(GO:0000104)
0.0 0.1 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0 0.1 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0 0.1 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.0 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.2 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.0 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.0 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.0 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.0 GO:0010861 thyroid hormone receptor activator activity(GO:0010861)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.0 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)
0.0 0.1 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.2 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.0 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.2 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.6 GO:0017022 myosin binding(GO:0017022)
0.0 0.0 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.0 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 0.3 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.0 GO:0016303 1-phosphatidylinositol-3-kinase activity(GO:0016303)
0.0 0.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.1 GO:0052760 4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.2 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.0 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 0.1 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.0 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.2 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.3 PID MYC PATHWAY C-MYC pathway
0.0 0.0 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.1 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.1 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.1 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.4 PID BMP PATHWAY BMP receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.5 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.0 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.3 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.2 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.0 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.0 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 2.3 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.2 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.1 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.2 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification