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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Rara

Z-value: 1.16

Motif logo

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Transcription factors associated with Rara

Gene Symbol Gene ID Gene Info
Rara
ENSMUSG00000037992.10 retinoic acid receptor, alpha

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_98971402_98971560Rara110690.098839-0.954.0e-03Click!
chr11_98941866_98942032Rara22370.1756880.882.1e-02Click!
chr11_98942156_98942339Rara25350.1597940.882.1e-02Click!
chr11_98937139_98937314Rara4720.6890950.862.8e-02Click!
chr11_98964767_98965121Rara45320.1196970.862.9e-02Click!

Activity of the Rara motif across conditions

Conditions sorted by the z-value of the Rara motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr8_115831765_115832080 0.80 Maf
 avian musculoaponeurotic fibrosarcoma oncogene homolog
 124128
 0.06
chr3_145834049_145834216 0.74 Ddah1
 dimethylarginine dimethylaminohydrolase 1
 23653
 0.18
chr6_126404787_126404969 0.72 Gm44431
 predicted gene, 44431
 68011
 0.1
chr7_140948066_140948469 0.66 Ifitm5
 interferon induced transmembrane protein 5
 2024
 0.12
chr11_53872113_53872322 0.66 Slc22a5
 solute carrier family 22 (organic cation transporter), member 5
 540
 0.66
chr4_138440154_138440340 0.62 Mul1
 mitochondrial ubiquitin ligase activator of NFKB 1
 5524
 0.14
chr5_135738165_135738332 0.61 Tmem120a
 transmembrane protein 120A
 1012
 0.35
chr1_191663564_191663926 0.58 Lpgat1
 lysophosphatidylglycerol acyltransferase 1
 54089
 0.09
chr8_4193425_4193618 0.57 Evi5l
 ecotropic viral integration site 5 like
 2229
 0.17
chr5_66200133_66200302 0.56 Gm15794
 predicted gene 15794
 1109
 0.34
chr8_84131316_84131478 0.53 Podnl1
 podocan-like 1
 3579
 0.09
chr6_82753132_82753283 0.52 Gm17034
 predicted gene 17034
 11075
 0.14
chr4_6539560_6539735 0.52 Gm11801
 predicted gene 11801
 86
 0.98
chr1_58475799_58475950 0.52 Orc2
 origin recognition complex, subunit 2
 5575
 0.13
chr7_126260333_126260533 0.51 Sbk1
 SH3-binding kinase 1
 11571
 0.11
chr2_12197838_12198004 0.50 Itga8
 integrin alpha 8
 4609
 0.27
chr18_36527710_36528079 0.50 Slc4a9
 solute carrier family 4, sodium bicarbonate cotransporter, member 9
 253
 0.88
chr4_131918798_131918960 0.50 Gm12992
 predicted gene 12992
 1150
 0.29
chr1_170501557_170501869 0.50 Nos1ap
 nitric oxide synthase 1 (neuronal) adaptor protein
 46799
 0.15
chr5_134571935_134572111 0.50 Mir7228
 microRNA 7228
 53
 0.95
chr11_115303297_115303464 0.49 Otop2
 otopetrin 2
 3783
 0.11
chr9_98429903_98430078 0.49 Rbp1
 retinol binding protein 1, cellular
 7029
 0.21
chr6_94998536_94998699 0.48 4930511E03Rik
 RIKEN cDNA 4930511E03 gene
 54783
 0.13
chr5_103783262_103783453 0.48 Aff1
 AF4/FMR2 family, member 1
 1002
 0.59
chr15_97059709_97059903 0.47 Slc38a4
 solute carrier family 38, member 4
 3850
 0.33
chr15_16566506_16566694 0.46 Gm2611
 predicted gene 2611
 33962
 0.19
chr15_10335815_10335966 0.45 Gm21973
 predicted gene 21973
 10510
 0.19
chr13_97453178_97453337 0.45 Gm8756
 predicted gene 8756
 5820
 0.18
chr1_140183261_140183634 0.44 Cfh
 complement component factor h
 36
 0.98
chr7_19965081_19965263 0.44 Ceacam20
 carcinoembryonic antigen-related cell adhesion molecule 20
 240
 0.83
chr15_79434871_79435022 0.44 Csnk1e
 casein kinase 1, epsilon
 1820
 0.21
chr11_120500689_120500856 0.43 Slc25a10
 solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10
 3047
 0.09
chr8_10531058_10531225 0.43 5330413D20Rik
 RIKEN cDNA 5330413D20 gene
 145772
 0.04
chr7_19865343_19865508 0.43 Ceacam16
 carcinoembryonic antigen-related cell adhesion molecule 16
 4126
 0.08
chr11_70585533_70585714 0.41 Mink1
 misshapen-like kinase 1 (zebrafish)
 13365
 0.07
chr4_118366670_118366829 0.41 Szt2
 SZT2 subunit of KICSTOR complex
 1683
 0.28
chrX_11574219_11574397 0.41 Gm14515
 predicted gene 14515
 27046
 0.22
chr13_52060383_52060534 0.41 Gm48190
 predicted gene, 48190
 36184
 0.14
chr9_44579542_44579697 0.41 Gm47230
 predicted gene, 47230
 8
 0.94
chr6_128481760_128482446 0.40 Pzp
 PZP, alpha-2-macroglobulin like
 5752
 0.09
chr7_68692846_68692997 0.40 Gm44692
 predicted gene 44692
 33546
 0.17
chr15_10338082_10338258 0.40 Gm21973
 predicted gene 21973
 12790
 0.18
chr14_65299395_65299546 0.40 Gm48433
 predicted gene, 48433
 26861
 0.13
chr11_120215894_120216125 0.39 Gm11770
 predicted gene 11770
 984
 0.37
chr2_158783086_158783239 0.39 Fam83d
 family with sequence similarity 83, member D
 1754
 0.34
chr3_118478170_118478340 0.39 Gm26871
 predicted gene, 26871
 20596
 0.14
chr5_64840100_64840327 0.39 Klf3
 Kruppel-like factor 3 (basic)
 13404
 0.15
chr8_91706641_91706804 0.39 Gm36325
 predicted gene, 36325
 7691
 0.14
chr11_86917162_86917343 0.39 Ypel2
 yippee like 2
 54772
 0.11
chr18_20989972_20990130 0.39 Rnf138
 ring finger protein 138
 11290
 0.2
chr8_79498769_79498920 0.39 Gm8077
 predicted gene 8077
 666
 0.57
chr8_85064057_85064246 0.39 Fbxw9
 F-box and WD-40 domain protein 9
 444
 0.52
chr6_115730698_115730849 0.38 Tmem40
 transmembrane protein 40
 4178
 0.13
chr19_42891636_42891940 0.38 Hps1
 HPS1, biogenesis of lysosomal organelles complex 3 subunit 1
 111810
 0.06
chr2_153493974_153494180 0.38 4930404H24Rik
 RIKEN cDNA 4930404H24 gene
 1287
 0.36
chr19_8567498_8567799 0.38 Gm6425
 predicted pseudogene 6425
 21548
 0.11
chr8_119419822_119419973 0.37 Osgin1
 oxidative stress induced growth inhibitor 1
 14227
 0.14
chr1_62821658_62821837 0.37 Gm4208
 predicted gene 4208
 10623
 0.19
chr10_105404051_105404220 0.37 Gm48203
 predicted gene, 48203
 9849
 0.19
chr2_132740163_132740333 0.37 Gm22245
 predicted gene, 22245
 23142
 0.11
chr5_66458954_66459109 0.36 Gm43794
 predicted gene 43794
 14608
 0.15
chr15_78925213_78925506 0.36 Lgals1
 lectin, galactose binding, soluble 1
 1366
 0.2
chr10_107383971_107384142 0.35 Gm38117
 predicted gene, 38117
 53303
 0.13
chr9_96379613_96379768 0.35 Atp1b3
 ATPase, Na+/K+ transporting, beta 3 polypeptide
 15248
 0.17
chr16_34965483_34965646 0.35 E130310I04Rik
 RIKEN cDNA E130310I04 gene
 6570
 0.17
chr17_14570462_14570613 0.35 Thbs2
 thrombospondin 2
 100329
 0.06
chr10_81102537_81102688 0.35 Mir5615-2
 microRNA 5615-2
 2004
 0.12
chr4_139978730_139978900 0.34 Klhdc7a
 kelch domain containing 7A
 10789
 0.16
chr3_88339093_88339486 0.34 Smg5
 Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)
 1431
 0.18
chr11_117203569_117203863 0.34 Septin9
 septin 9
 4055
 0.2
chr11_82858816_82858975 0.34 Rffl
 ring finger and FYVE like domain containing protein
 11849
 0.1
chr5_63969602_63969775 0.34 Rell1
 RELT-like 1
 791
 0.59
chr10_8912248_8912575 0.34 Gm48727
 predicted gene, 48727
 8430
 0.16
chr11_113725344_113725520 0.34 Cdc42ep4
 CDC42 effector protein (Rho GTPase binding) 4
 13890
 0.12
chr7_29251255_29251571 0.34 2200002D01Rik
 RIKEN cDNA 2200002D01 gene
 2947
 0.13
chr1_183790757_183790934 0.33 Gm34068
 predicted gene, 34068
 41868
 0.18
chr2_166467245_166467396 0.33 5031425F14Rik
 RIKEN cDNA 5031425F14 gene
 19869
 0.19
chr1_71634492_71634670 0.33 Fn1
 fibronectin 1
 6707
 0.2
chr19_4436418_4436609 0.33 A930001C03Rik
 RIKEN cDNA A930001C03 gene
 2490
 0.17
chr7_98572441_98572789 0.33 A630091E08Rik
 RIKEN cDNA A630091E08 gene
 9625
 0.16
chr10_61929391_61929572 0.32 Gm5750
 predicted gene 5750
 30143
 0.16
chr15_99792342_99792511 0.32 Lima1
 LIM domain and actin binding 1
 8453
 0.08
chr2_70421553_70421719 0.32 Rpl9-ps7
 ribosomal protein L9, pseudogene 7
 37346
 0.14
chr14_97847704_97847876 0.32 Gm25831
 predicted gene, 25831
 120201
 0.06
chr5_134629599_134629763 0.32 Eif4h
 eukaryotic translation initiation factor 4H
 9621
 0.11
chr5_32155495_32155671 0.32 Fosl2
 fos-like antigen 2
 9062
 0.15
chrX_43495267_43495434 0.32 Gm14588
 predicted gene 14588
 21396
 0.21
chr6_31100129_31100294 0.31 Gm13833
 predicted gene 13833
 2635
 0.17
chr13_59832569_59832762 0.31 Gm34961
 predicted gene, 34961
 9399
 0.11
chr11_96324315_96324468 0.31 Hoxb3
 homeobox B3
 1065
 0.25
chr3_37642128_37642470 0.31 Gm42922
 predicted gene 42922
 1643
 0.21
chr6_42221324_42221475 0.31 Tas2r144
 taste receptor, type 2, member 144
 6071
 0.14
chr19_54834637_54834803 0.31 Gm50191
 predicted gene, 50191
 102004
 0.08
chr15_82374486_82374674 0.31 Cyp2d22
 cytochrome P450, family 2, subfamily d, polypeptide 22
 742
 0.37
chr7_16287899_16288054 0.31 Ccdc9
 coiled-coil domain containing 9
 1181
 0.32
chr4_44994891_44995176 0.31 Grhpr
 glyoxylate reductase/hydroxypyruvate reductase
 13533
 0.1
chr3_67551330_67551501 0.30 Gm35299
 predicted gene, 35299
 2010
 0.23
chr1_152032225_152032416 0.30 1700025G04Rik
 RIKEN cDNA 1700025G04 gene
 22972
 0.23
chr3_142707130_142707285 0.30 Kyat3
 kynurenine aminotransferase 3
 6113
 0.15
chr11_100855277_100855460 0.30 Stat5a
 signal transducer and activator of transcription 5A
 3983
 0.16
chr11_109559331_109559545 0.30 Arsg
 arylsulfatase G
 15684
 0.15
chr10_80136261_80136428 0.30 Cbarp
 calcium channel, voltage-dependent, beta subunit associated regulatory protein
 756
 0.4
chr12_109512584_109512771 0.30 Gm34081
 predicted gene, 34081
 4063
 0.07
chr13_94063212_94063363 0.29 Lhfpl2
 lipoma HMGIC fusion partner-like 2
 5455
 0.2
chr14_16575472_16575639 0.29 Rarb
 retinoic acid receptor, beta
 12
 0.52
chr9_61164927_61165078 0.29 I730028E13Rik
 RIKEN cDNA I730028E13 gene
 26487
 0.14
chr1_174748737_174748905 0.29 Fmn2
 formin 2
 34495
 0.22
chr1_9645605_9645800 0.29 Gm29520
 predicted gene 29520
 5120
 0.16
chr4_128648691_128648859 0.29 Phc2
 polyhomeotic 2
 5927
 0.17
chrX_11630030_11630183 0.29 Gm14515
 predicted gene 14515
 28752
 0.21
chr2_104663420_104663722 0.29 Cstf3
 cleavage stimulation factor, 3' pre-RNA, subunit 3
 95
 0.96
chr2_105235818_105235986 0.28 Them7
 thioesterase superfamily member 7
 11560
 0.24
chr11_51619305_51619469 0.28 Nhp2
 NHP2 ribonucleoprotein
 348
 0.8
chr10_8071988_8072183 0.28 Gm48614
 predicted gene, 48614
 50793
 0.15
chr16_38286019_38286177 0.28 Nr1i2
 nuclear receptor subfamily 1, group I, member 2
 8726
 0.15
chr18_34927551_34927712 0.28 Etf1
 eukaryotic translation termination factor 1
 4376
 0.14
chr11_110032630_110032781 0.28 Abca8a
 ATP-binding cassette, sub-family A (ABC1), member 8a
 2624
 0.32
chr8_115968249_115968411 0.28 Gm45733
 predicted gene 45733
 3741
 0.37
chr12_83087732_83087912 0.27 Gm29530
 predicted gene 29530
 11052
 0.17
chr9_118655096_118655280 0.27 Itga9
 integrin alpha 9
 30647
 0.17
chr10_97387218_97387458 0.27 Mir3966
 microRNA 3966
 36140
 0.19
chr9_109090535_109090842 0.27 Plxnb1
 plexin B1
 4701
 0.1
chr16_18715486_18715659 0.27 Rps2-ps7
 ribosomal protein S2, pseudogene 7
 33356
 0.12
chr14_46419483_46419645 0.27 Gm15221
 predicted gene 15221
 17291
 0.12
chr17_8305079_8305235 0.27 4930506C21Rik
 RIKEN cDNA 4930506C21 gene
 5895
 0.12
chr4_118233934_118234146 0.27 Ptprf
 protein tyrosine phosphatase, receptor type, F
 1976
 0.29
chr12_25132357_25132520 0.27 Gm17746
 predicted gene, 17746
 3264
 0.21
chr3_148935992_148936150 0.27 Adgrl2
 adhesion G protein-coupled receptor L2
 18564
 0.22
chr11_16920982_16921140 0.27 Egfr
 epidermal growth factor receptor
 15876
 0.16
chr4_41524935_41525096 0.27 Fam219a
 family with sequence similarity 219, member A
 245
 0.85
chr3_122513095_122513259 0.27 Bcar3
 breast cancer anti-estrogen resistance 3
 955
 0.47
chr7_111020937_111021103 0.27 Ctr9
 CTR9 homolog, Paf1/RNA polymerase II complex component
 7931
 0.17
chr14_26557730_26557942 0.27 Gm18215
 predicted gene, 18215
 5240
 0.13
chr8_104375235_104375402 0.27 Gm45877
 predicted gene 45877
 11650
 0.09
chr9_70827748_70828187 0.27 Gm3436
 predicted pseudogene 3436
 24609
 0.16
chr15_77072900_77073074 0.26 Gm24753
 predicted gene, 24753
 5196
 0.12
chr6_91111481_91112156 0.26 Nup210
 nucleoporin 210
 4978
 0.17
chr6_128549526_128549695 0.26 A2ml1
 alpha-2-macroglobulin like 1
 3668
 0.12
chr1_183414419_183414590 0.26 Gm37986
 predicted gene, 37986
 38
 0.96
chr12_110219862_110220027 0.26 Gm40576
 predicted gene, 40576
 16418
 0.11
chr7_110060209_110060360 0.26 Zfp143
 zinc finger protein 143
 933
 0.32
chr11_100318043_100318206 0.26 Eif1
 eukaryotic translation initiation factor 1
 1761
 0.17
chr10_28422676_28422859 0.26 Ptprk
 protein tyrosine phosphatase, receptor type, K
 137384
 0.05
chr10_120384864_120385074 0.26 9230105E05Rik
 RIKEN cDNA 9230105E05 gene
 4554
 0.2
chrX_163768401_163768583 0.26 Rnf138rt1
 ring finger protein 138, retrogene 1
 7163
 0.23
chr15_68255673_68255836 0.26 Zfat
 zinc finger and AT hook domain containing
 3033
 0.26
chr1_165679726_165679916 0.26 Gm44458
 predicted gene, 44458
 14944
 0.1
chr5_105239714_105239885 0.26 Gbp10
 guanylate-binding protein 10
 266
 0.92
chr4_35134107_35134262 0.26 Ifnk
 interferon kappa
 17872
 0.17
chr14_70207050_70207221 0.26 Sorbs3
 sorbin and SH3 domain containing 3
 502
 0.48
chr6_49150440_49150597 0.26 Gm18010
 predicted gene, 18010
 22241
 0.13
chr1_191449557_191449745 0.26 Gm32200
 predicted gene, 32200
 15397
 0.13
chr2_133495524_133495962 0.25 Gm14100
 predicted gene 14100
 32625
 0.16
chr11_94589492_94589674 0.25 Acsf2
 acyl-CoA synthetase family member 2
 12186
 0.11
chr6_144759587_144759981 0.25 Sox5
 SRY (sex determining region Y)-box 5
 22135
 0.15
chr10_99555138_99555310 0.25 Gm48085
 predicted gene, 48085
 17155
 0.18
chr7_16830530_16830865 0.25 Strn4
 striatin, calmodulin binding protein 4
 402
 0.73
chr13_68226599_68226750 0.25 AA414992
 expressed sequence AA414992
 45380
 0.16
chr7_45711383_45711838 0.25 Sphk2
 sphingosine kinase 2
 1833
 0.12
chr8_66579826_66579979 0.25 Gm16330
 predicted gene 16330
 9106
 0.22
chr10_92081958_92082460 0.25 Rmst
 rhabdomyosarcoma 2 associated transcript (non-coding RNA)
 6580
 0.22
chr11_86921503_86921665 0.25 Ypel2
 yippee like 2
 50440
 0.12
chr16_20674169_20674320 0.25 Eif4g1
 eukaryotic translation initiation factor 4, gamma 1
 133
 0.89
chr10_28167171_28167473 0.25 Gm22370
 predicted gene, 22370
 46799
 0.17
chr3_133534210_133534372 0.24 Tet2
 tet methylcytosine dioxygenase 2
 9995
 0.17
chr9_108913748_108913914 0.24 Tmem89
 transmembrane protein 89
 788
 0.4
chr14_69392700_69392874 0.24 Gm21451
 predicted gene, 21451
 1933
 0.21
chr18_5186924_5187075 0.24 Gm26682
 predicted gene, 26682
 21268
 0.24
chr11_75462092_75462507 0.24 Tlcd2
 TLC domain containing 2
 584
 0.35
chr1_55053215_55053405 0.24 E330011M16Rik
 RIKEN cDNA E330011M16 gene
 198
 0.72
chr1_36080918_36081086 0.24 Hs6st1
 heparan sulfate 6-O-sulfotransferase 1
 12602
 0.14
chr16_22900205_22900497 0.24 Ahsg
 alpha-2-HS-glycoprotein
 5487
 0.13
chr8_22637028_22637191 0.24 Dkk4
 dickkopf WNT signaling pathway inhibitor 4
 13066
 0.13
chr19_32543108_32543270 0.24 Gm36419
 predicted gene, 36419
 159
 0.96
chr11_7196610_7196788 0.24 Igfbp1
 insulin-like growth factor binding protein 1
 1083
 0.48
chr8_69887766_69887933 0.24 Cilp2
 cartilage intermediate layer protein 2
 162
 0.69
chr11_16742202_16742481 0.24 Gm25698
 predicted gene, 25698
 9630
 0.19
chr4_139383343_139383534 0.24 Ubr4
 ubiquitin protein ligase E3 component n-recognin 4
 2769
 0.16
chr9_74931997_74932158 0.23 Fam214a
 family with sequence similarity 214, member A
 20807
 0.17
chr2_128179604_128179779 0.23 Gm14009
 predicted gene 14009
 10296
 0.22
chr5_122882739_122882908 0.23 Kdm2b
 lysine (K)-specific demethylase 2B
 590
 0.67
chr2_5600300_5600460 0.23 Gm13216
 predicted gene 13216
 3191
 0.34
chr19_60828743_60828894 0.23 Fam45a
 family with sequence similarity 45, member A
 1734
 0.25
chr9_25570473_25570647 0.23 Gm25346
 predicted gene, 25346
 755
 0.7
chr12_105784205_105784562 0.23 Papola
 poly (A) polymerase alpha
 311
 0.9
chr3_38589085_38589252 0.23 Gm43538
 predicted gene 43538
 25079
 0.16
chr11_120543038_120543310 0.23 Mcrip1
 MAPK regulated corepressor interacting protein 1
 6527
 0.06
chr8_70552951_70553110 0.23 Ell
 elongation factor RNA polymerase II
 13342
 0.08
chr13_74769953_74770127 0.23 Cast
 calpastatin
 550
 0.67
chr2_148443567_148443727 0.23 Cd93
 CD93 antigen
 84
 0.97
chr6_31323903_31324093 0.23 2210408F21Rik
 RIKEN cDNA 2210408F21 gene
 2027
 0.28
chr11_106967758_106967936 0.23 Gm11707
 predicted gene 11707
 5243
 0.15
chr6_115480476_115480638 0.23 Gm44079
 predicted gene, 44079
 15567
 0.16
chr4_140770556_140770730 0.23 Padi4
 peptidyl arginine deiminase, type IV
 3593
 0.16
chr4_106564660_106564819 0.23 Dhcr24
 24-dehydrocholesterol reductase
 3701
 0.14
chr15_80720254_80720552 0.23 Gm49512
 predicted gene, 49512
 8132
 0.15
chr4_60424050_60424352 0.23 Mup9
 major urinary protein 9
 2249
 0.23
chr4_148085280_148085458 0.23 Agtrap
 angiotensin II, type I receptor-associated protein
 593
 0.56
chr13_93177685_93177846 0.23 Tent2
 terminal nucleotidyltransferase 2
 9336
 0.2
chr1_10099708_10099862 0.22 Cspp1
 centrosome and spindle pole associated protein 1
 3921
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Rara

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0042891 antibiotic transport(GO:0042891)
0.1 0.2 GO:0040031 snRNA modification(GO:0040031)
0.1 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.2 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.2 GO:0006524 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.2 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0 0.1 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.0 0.2 GO:1901628 positive regulation of postsynaptic membrane organization(GO:1901628)
0.0 0.2 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0009157 deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 0.1 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.2 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.1 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:1990169 detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.0 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
0.0 0.1 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.2 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.0 GO:0097195 pilomotor reflex(GO:0097195)
0.0 0.1 GO:0006598 polyamine catabolic process(GO:0006598)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.0 0.0 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.1 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.4 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0071286 cellular response to magnesium ion(GO:0071286)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.0 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.0 GO:0003133 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.0 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.0 GO:0046645 positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0 0.0 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.1 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.0 GO:0060916 mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0 0.0 GO:0015744 succinate transport(GO:0015744)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.1 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.0 GO:0060112 generation of ovulation cycle rhythm(GO:0060112)
0.0 0.0 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0035740 CD8-positive, alpha-beta T cell proliferation(GO:0035740)
0.0 0.1 GO:0006056 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.1 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.0 GO:0045586 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0 0.0 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.0 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.0 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:0044004 killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:2000611 positive regulation of thyroid hormone generation(GO:2000611)
0.0 0.0 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.0 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.1 GO:0090049 regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.0 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.0 GO:0070340 detection of bacterial lipopeptide(GO:0070340)
0.0 0.0 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.1 GO:0006555 methionine metabolic process(GO:0006555)
0.0 0.0 GO:2000173 negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0 0.0 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.0 0.1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.0 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.2 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0045116 protein neddylation(GO:0045116)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:2000598 regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0 0.1 GO:1900044 regulation of protein K63-linked ubiquitination(GO:1900044)
0.0 0.0 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.0 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0046697 decidualization(GO:0046697)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.2 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.0 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.1 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0046133 pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0 0.0 GO:0009169 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.0 GO:0060789 hair follicle placode formation(GO:0060789)
0.0 0.0 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.1 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.1 GO:0030313 cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0 0.1 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.0 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0 0.1 GO:0005767 secondary lysosome(GO:0005767)
0.0 0.0 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.0 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.0 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.2 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0016882 cyclo-ligase activity(GO:0016882)
0.0 0.4 GO:0001846 opsonin binding(GO:0001846)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.1 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.1 GO:0048030 disaccharide binding(GO:0048030)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0018568 2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0 0.1 GO:0018586 mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.1 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0032552 deoxyribonucleotide binding(GO:0032552)
0.0 0.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.4 GO:0015301 anion:anion antiporter activity(GO:0015301)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.0 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.0 0.0 GO:0015141 succinate transmembrane transporter activity(GO:0015141)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.0 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.0 GO:0004942 anaphylatoxin receptor activity(GO:0004942)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.1 GO:0019841 retinol binding(GO:0019841)
0.0 0.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.0 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0015198 oligopeptide transporter activity(GO:0015198)
0.0 0.1 GO:0034902 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.2 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.0 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.0 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.0 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.2 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.0 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.3 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.0 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline