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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Rara

Z-value: 1.16

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Transcription factors associated with Rara

Gene Symbol	Gene ID	Gene Info
Rara Ensembl NCBI MGI UniProt	ENSMUSG00000037992.10	Rara

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Rara	chr11_98971402_98971560	11069	0.098839	-0.95	4.0e-03	Click!
Rara	chr11_98941866_98942032	2237	0.175688	0.88	2.1e-02	Click!
Rara	chr11_98942156_98942339	2535	0.159794	0.88	2.1e-02	Click!
Rara	chr11_98937139_98937314	472	0.689095	0.86	2.8e-02	Click!
Rara	chr11_98964767_98965121	4532	0.119697	0.86	2.9e-02	Click!

Activity of the Rara motif across conditions

Conditions sorted by the z-value of the Rara motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr8_115831765_115832080	0.80	Maf	avian musculoaponeurotic fibrosarcoma oncogene homolog	124128	0.06
chr3_145834049_145834216	0.74	Ddah1	dimethylarginine dimethylaminohydrolase 1	23653	0.18
chr6_126404787_126404969	0.72	Gm44431	predicted gene, 44431	68011	0.1
chr7_140948066_140948469	0.66	Ifitm5	interferon induced transmembrane protein 5	2024	0.12
chr11_53872113_53872322	0.66	Slc22a5	solute carrier family 22 (organic cation transporter), member 5	540	0.66
chr4_138440154_138440340	0.62	Mul1	mitochondrial ubiquitin ligase activator of NFKB 1	5524	0.14
chr5_135738165_135738332	0.61	Tmem120a	transmembrane protein 120A	1012	0.35
chr1_191663564_191663926	0.58	Lpgat1	lysophosphatidylglycerol acyltransferase 1	54089	0.09
chr8_4193425_4193618	0.57	Evi5l	ecotropic viral integration site 5 like	2229	0.17
chr5_66200133_66200302	0.56	Gm15794	predicted gene 15794	1109	0.34
chr8_84131316_84131478	0.53	Podnl1	podocan-like 1	3579	0.09
chr6_82753132_82753283	0.52	Gm17034	predicted gene 17034	11075	0.14
chr4_6539560_6539735	0.52	Gm11801	predicted gene 11801	86	0.98
chr1_58475799_58475950	0.52	Orc2	origin recognition complex, subunit 2	5575	0.13
chr7_126260333_126260533	0.51	Sbk1	SH3-binding kinase 1	11571	0.11
chr2_12197838_12198004	0.50	Itga8	integrin alpha 8	4609	0.27
chr18_36527710_36528079	0.50	Slc4a9	solute carrier family 4, sodium bicarbonate cotransporter, member 9	253	0.88
chr4_131918798_131918960	0.50	Gm12992	predicted gene 12992	1150	0.29
chr1_170501557_170501869	0.50	Nos1ap	nitric oxide synthase 1 (neuronal) adaptor protein	46799	0.15
chr5_134571935_134572111	0.50	Mir7228	microRNA 7228	53	0.95
chr11_115303297_115303464	0.49	Otop2	otopetrin 2	3783	0.11
chr9_98429903_98430078	0.49	Rbp1	retinol binding protein 1, cellular	7029	0.21
chr6_94998536_94998699	0.48	4930511E03Rik	RIKEN cDNA 4930511E03 gene	54783	0.13
chr5_103783262_103783453	0.48	Aff1	AF4/FMR2 family, member 1	1002	0.59
chr15_97059709_97059903	0.47	Slc38a4	solute carrier family 38, member 4	3850	0.33
chr15_16566506_16566694	0.46	Gm2611	predicted gene 2611	33962	0.19
chr15_10335815_10335966	0.45	Gm21973	predicted gene 21973	10510	0.19
chr13_97453178_97453337	0.45	Gm8756	predicted gene 8756	5820	0.18
chr1_140183261_140183634	0.44	Cfh	complement component factor h	36	0.98
chr7_19965081_19965263	0.44	Ceacam20	carcinoembryonic antigen-related cell adhesion molecule 20	240	0.83
chr15_79434871_79435022	0.44	Csnk1e	casein kinase 1, epsilon	1820	0.21
chr11_120500689_120500856	0.43	Slc25a10	solute carrier family 25 (mitochondrial carrier, dicarboxylate transporter), member 10	3047	0.09
chr8_10531058_10531225	0.43	5330413D20Rik	RIKEN cDNA 5330413D20 gene	145772	0.04
chr7_19865343_19865508	0.43	Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	4126	0.08
chr11_70585533_70585714	0.41	Mink1	misshapen-like kinase 1 (zebrafish)	13365	0.07
chr4_118366670_118366829	0.41	Szt2	SZT2 subunit of KICSTOR complex	1683	0.28
chrX_11574219_11574397	0.41	Gm14515	predicted gene 14515	27046	0.22
chr13_52060383_52060534	0.41	Gm48190	predicted gene, 48190	36184	0.14
chr9_44579542_44579697	0.41	Gm47230	predicted gene, 47230	8	0.94
chr6_128481760_128482446	0.40	Pzp	PZP, alpha-2-macroglobulin like	5752	0.09
chr7_68692846_68692997	0.40	Gm44692	predicted gene 44692	33546	0.17
chr15_10338082_10338258	0.40	Gm21973	predicted gene 21973	12790	0.18
chr14_65299395_65299546	0.40	Gm48433	predicted gene, 48433	26861	0.13
chr11_120215894_120216125	0.39	Gm11770	predicted gene 11770	984	0.37
chr2_158783086_158783239	0.39	Fam83d	family with sequence similarity 83, member D	1754	0.34
chr3_118478170_118478340	0.39	Gm26871	predicted gene, 26871	20596	0.14
chr5_64840100_64840327	0.39	Klf3	Kruppel-like factor 3 (basic)	13404	0.15
chr8_91706641_91706804	0.39	Gm36325	predicted gene, 36325	7691	0.14
chr11_86917162_86917343	0.39	Ypel2	yippee like 2	54772	0.11
chr18_20989972_20990130	0.39	Rnf138	ring finger protein 138	11290	0.2
chr8_79498769_79498920	0.39	Gm8077	predicted gene 8077	666	0.57
chr8_85064057_85064246	0.39	Fbxw9	F-box and WD-40 domain protein 9	444	0.52
chr6_115730698_115730849	0.38	Tmem40	transmembrane protein 40	4178	0.13
chr19_42891636_42891940	0.38	Hps1	HPS1, biogenesis of lysosomal organelles complex 3 subunit 1	111810	0.06
chr2_153493974_153494180	0.38	4930404H24Rik	RIKEN cDNA 4930404H24 gene	1287	0.36
chr19_8567498_8567799	0.38	Gm6425	predicted pseudogene 6425	21548	0.11
chr8_119419822_119419973	0.37	Osgin1	oxidative stress induced growth inhibitor 1	14227	0.14
chr1_62821658_62821837	0.37	Gm4208	predicted gene 4208	10623	0.19
chr10_105404051_105404220	0.37	Gm48203	predicted gene, 48203	9849	0.19
chr2_132740163_132740333	0.37	Gm22245	predicted gene, 22245	23142	0.11
chr5_66458954_66459109	0.36	Gm43794	predicted gene 43794	14608	0.15
chr15_78925213_78925506	0.36	Lgals1	lectin, galactose binding, soluble 1	1366	0.2
chr10_107383971_107384142	0.35	Gm38117	predicted gene, 38117	53303	0.13
chr9_96379613_96379768	0.35	Atp1b3	ATPase, Na+/K+ transporting, beta 3 polypeptide	15248	0.17
chr16_34965483_34965646	0.35	E130310I04Rik	RIKEN cDNA E130310I04 gene	6570	0.17
chr17_14570462_14570613	0.35	Thbs2	thrombospondin 2	100329	0.06
chr10_81102537_81102688	0.35	Mir5615-2	microRNA 5615-2	2004	0.12
chr4_139978730_139978900	0.34	Klhdc7a	kelch domain containing 7A	10789	0.16
chr3_88339093_88339486	0.34	Smg5	Smg-5 homolog, nonsense mediated mRNA decay factor (C. elegans)	1431	0.18
chr11_117203569_117203863	0.34	Septin9	septin 9	4055	0.2
chr11_82858816_82858975	0.34	Rffl	ring finger and FYVE like domain containing protein	11849	0.1
chr5_63969602_63969775	0.34	Rell1	RELT-like 1	791	0.59
chr10_8912248_8912575	0.34	Gm48727	predicted gene, 48727	8430	0.16
chr11_113725344_113725520	0.34	Cdc42ep4	CDC42 effector protein (Rho GTPase binding) 4	13890	0.12
chr7_29251255_29251571	0.34	2200002D01Rik	RIKEN cDNA 2200002D01 gene	2947	0.13
chr1_183790757_183790934	0.33	Gm34068	predicted gene, 34068	41868	0.18
chr2_166467245_166467396	0.33	5031425F14Rik	RIKEN cDNA 5031425F14 gene	19869	0.19
chr1_71634492_71634670	0.33	Fn1	fibronectin 1	6707	0.2
chr19_4436418_4436609	0.33	A930001C03Rik	RIKEN cDNA A930001C03 gene	2490	0.17
chr7_98572441_98572789	0.33	A630091E08Rik	RIKEN cDNA A630091E08 gene	9625	0.16
chr10_61929391_61929572	0.32	Gm5750	predicted gene 5750	30143	0.16
chr15_99792342_99792511	0.32	Lima1	LIM domain and actin binding 1	8453	0.08
chr2_70421553_70421719	0.32	Rpl9-ps7	ribosomal protein L9, pseudogene 7	37346	0.14
chr14_97847704_97847876	0.32	Gm25831	predicted gene, 25831	120201	0.06
chr5_134629599_134629763	0.32	Eif4h	eukaryotic translation initiation factor 4H	9621	0.11
chr5_32155495_32155671	0.32	Fosl2	fos-like antigen 2	9062	0.15
chrX_43495267_43495434	0.32	Gm14588	predicted gene 14588	21396	0.21
chr6_31100129_31100294	0.31	Gm13833	predicted gene 13833	2635	0.17
chr13_59832569_59832762	0.31	Gm34961	predicted gene, 34961	9399	0.11
chr11_96324315_96324468	0.31	Hoxb3	homeobox B3	1065	0.25
chr3_37642128_37642470	0.31	Gm42922	predicted gene 42922	1643	0.21
chr6_42221324_42221475	0.31	Tas2r144	taste receptor, type 2, member 144	6071	0.14
chr19_54834637_54834803	0.31	Gm50191	predicted gene, 50191	102004	0.08
chr15_82374486_82374674	0.31	Cyp2d22	cytochrome P450, family 2, subfamily d, polypeptide 22	742	0.37
chr7_16287899_16288054	0.31	Ccdc9	coiled-coil domain containing 9	1181	0.32
chr4_44994891_44995176	0.31	Grhpr	glyoxylate reductase/hydroxypyruvate reductase	13533	0.1
chr3_67551330_67551501	0.30	Gm35299	predicted gene, 35299	2010	0.23
chr1_152032225_152032416	0.30	1700025G04Rik	RIKEN cDNA 1700025G04 gene	22972	0.23
chr3_142707130_142707285	0.30	Kyat3	kynurenine aminotransferase 3	6113	0.15
chr11_100855277_100855460	0.30	Stat5a	signal transducer and activator of transcription 5A	3983	0.16
chr11_109559331_109559545	0.30	Arsg	arylsulfatase G	15684	0.15
chr10_80136261_80136428	0.30	Cbarp	calcium channel, voltage-dependent, beta subunit associated regulatory protein	756	0.4
chr12_109512584_109512771	0.30	Gm34081	predicted gene, 34081	4063	0.07
chr13_94063212_94063363	0.29	Lhfpl2	lipoma HMGIC fusion partner-like 2	5455	0.2
chr14_16575472_16575639	0.29	Rarb	retinoic acid receptor, beta	12	0.52
chr9_61164927_61165078	0.29	I730028E13Rik	RIKEN cDNA I730028E13 gene	26487	0.14
chr1_174748737_174748905	0.29	Fmn2	formin 2	34495	0.22
chr1_9645605_9645800	0.29	Gm29520	predicted gene 29520	5120	0.16
chr4_128648691_128648859	0.29	Phc2	polyhomeotic 2	5927	0.17
chrX_11630030_11630183	0.29	Gm14515	predicted gene 14515	28752	0.21
chr2_104663420_104663722	0.29	Cstf3	cleavage stimulation factor, 3' pre-RNA, subunit 3	95	0.96
chr2_105235818_105235986	0.28	Them7	thioesterase superfamily member 7	11560	0.24
chr11_51619305_51619469	0.28	Nhp2	NHP2 ribonucleoprotein	348	0.8
chr10_8071988_8072183	0.28	Gm48614	predicted gene, 48614	50793	0.15
chr16_38286019_38286177	0.28	Nr1i2	nuclear receptor subfamily 1, group I, member 2	8726	0.15
chr18_34927551_34927712	0.28	Etf1	eukaryotic translation termination factor 1	4376	0.14
chr11_110032630_110032781	0.28	Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a	2624	0.32
chr8_115968249_115968411	0.28	Gm45733	predicted gene 45733	3741	0.37
chr12_83087732_83087912	0.27	Gm29530	predicted gene 29530	11052	0.17
chr9_118655096_118655280	0.27	Itga9	integrin alpha 9	30647	0.17
chr10_97387218_97387458	0.27	Mir3966	microRNA 3966	36140	0.19
chr9_109090535_109090842	0.27	Plxnb1	plexin B1	4701	0.1
chr16_18715486_18715659	0.27	Rps2-ps7	ribosomal protein S2, pseudogene 7	33356	0.12
chr14_46419483_46419645	0.27	Gm15221	predicted gene 15221	17291	0.12
chr17_8305079_8305235	0.27	4930506C21Rik	RIKEN cDNA 4930506C21 gene	5895	0.12
chr4_118233934_118234146	0.27	Ptprf	protein tyrosine phosphatase, receptor type, F	1976	0.29
chr12_25132357_25132520	0.27	Gm17746	predicted gene, 17746	3264	0.21
chr3_148935992_148936150	0.27	Adgrl2	adhesion G protein-coupled receptor L2	18564	0.22
chr11_16920982_16921140	0.27	Egfr	epidermal growth factor receptor	15876	0.16
chr4_41524935_41525096	0.27	Fam219a	family with sequence similarity 219, member A	245	0.85
chr3_122513095_122513259	0.27	Bcar3	breast cancer anti-estrogen resistance 3	955	0.47
chr7_111020937_111021103	0.27	Ctr9	CTR9 homolog, Paf1/RNA polymerase II complex component	7931	0.17
chr14_26557730_26557942	0.27	Gm18215	predicted gene, 18215	5240	0.13
chr8_104375235_104375402	0.27	Gm45877	predicted gene 45877	11650	0.09
chr9_70827748_70828187	0.27	Gm3436	predicted pseudogene 3436	24609	0.16
chr15_77072900_77073074	0.26	Gm24753	predicted gene, 24753	5196	0.12
chr6_91111481_91112156	0.26	Nup210	nucleoporin 210	4978	0.17
chr6_128549526_128549695	0.26	A2ml1	alpha-2-macroglobulin like 1	3668	0.12
chr1_183414419_183414590	0.26	Gm37986	predicted gene, 37986	38	0.96
chr12_110219862_110220027	0.26	Gm40576	predicted gene, 40576	16418	0.11
chr7_110060209_110060360	0.26	Zfp143	zinc finger protein 143	933	0.32
chr11_100318043_100318206	0.26	Eif1	eukaryotic translation initiation factor 1	1761	0.17
chr10_28422676_28422859	0.26	Ptprk	protein tyrosine phosphatase, receptor type, K	137384	0.05
chr10_120384864_120385074	0.26	9230105E05Rik	RIKEN cDNA 9230105E05 gene	4554	0.2
chrX_163768401_163768583	0.26	Rnf138rt1	ring finger protein 138, retrogene 1	7163	0.23
chr15_68255673_68255836	0.26	Zfat	zinc finger and AT hook domain containing	3033	0.26
chr1_165679726_165679916	0.26	Gm44458	predicted gene, 44458	14944	0.1
chr5_105239714_105239885	0.26	Gbp10	guanylate-binding protein 10	266	0.92
chr4_35134107_35134262	0.26	Ifnk	interferon kappa	17872	0.17
chr14_70207050_70207221	0.26	Sorbs3	sorbin and SH3 domain containing 3	502	0.48
chr6_49150440_49150597	0.26	Gm18010	predicted gene, 18010	22241	0.13
chr1_191449557_191449745	0.26	Gm32200	predicted gene, 32200	15397	0.13
chr2_133495524_133495962	0.25	Gm14100	predicted gene 14100	32625	0.16
chr11_94589492_94589674	0.25	Acsf2	acyl-CoA synthetase family member 2	12186	0.11
chr6_144759587_144759981	0.25	Sox5	SRY (sex determining region Y)-box 5	22135	0.15
chr10_99555138_99555310	0.25	Gm48085	predicted gene, 48085	17155	0.18
chr7_16830530_16830865	0.25	Strn4	striatin, calmodulin binding protein 4	402	0.73
chr13_68226599_68226750	0.25	AA414992	expressed sequence AA414992	45380	0.16
chr7_45711383_45711838	0.25	Sphk2	sphingosine kinase 2	1833	0.12
chr8_66579826_66579979	0.25	Gm16330	predicted gene 16330	9106	0.22
chr10_92081958_92082460	0.25	Rmst	rhabdomyosarcoma 2 associated transcript (non-coding RNA)	6580	0.22
chr11_86921503_86921665	0.25	Ypel2	yippee like 2	50440	0.12
chr16_20674169_20674320	0.25	Eif4g1	eukaryotic translation initiation factor 4, gamma 1	133	0.89
chr10_28167171_28167473	0.25	Gm22370	predicted gene, 22370	46799	0.17
chr3_133534210_133534372	0.24	Tet2	tet methylcytosine dioxygenase 2	9995	0.17
chr9_108913748_108913914	0.24	Tmem89	transmembrane protein 89	788	0.4
chr14_69392700_69392874	0.24	Gm21451	predicted gene, 21451	1933	0.21
chr18_5186924_5187075	0.24	Gm26682	predicted gene, 26682	21268	0.24
chr11_75462092_75462507	0.24	Tlcd2	TLC domain containing 2	584	0.35
chr1_55053215_55053405	0.24	E330011M16Rik	RIKEN cDNA E330011M16 gene	198	0.72
chr1_36080918_36081086	0.24	Hs6st1	heparan sulfate 6-O-sulfotransferase 1	12602	0.14
chr16_22900205_22900497	0.24	Ahsg	alpha-2-HS-glycoprotein	5487	0.13
chr8_22637028_22637191	0.24	Dkk4	dickkopf WNT signaling pathway inhibitor 4	13066	0.13
chr19_32543108_32543270	0.24	Gm36419	predicted gene, 36419	159	0.96
chr11_7196610_7196788	0.24	Igfbp1	insulin-like growth factor binding protein 1	1083	0.48
chr8_69887766_69887933	0.24	Cilp2	cartilage intermediate layer protein 2	162	0.69
chr11_16742202_16742481	0.24	Gm25698	predicted gene, 25698	9630	0.19
chr4_139383343_139383534	0.24	Ubr4	ubiquitin protein ligase E3 component n-recognin 4	2769	0.16
chr9_74931997_74932158	0.23	Fam214a	family with sequence similarity 214, member A	20807	0.17
chr2_128179604_128179779	0.23	Gm14009	predicted gene 14009	10296	0.22
chr5_122882739_122882908	0.23	Kdm2b	lysine (K)-specific demethylase 2B	590	0.67
chr2_5600300_5600460	0.23	Gm13216	predicted gene 13216	3191	0.34
chr19_60828743_60828894	0.23	Fam45a	family with sequence similarity 45, member A	1734	0.25
chr9_25570473_25570647	0.23	Gm25346	predicted gene, 25346	755	0.7
chr12_105784205_105784562	0.23	Papola	poly (A) polymerase alpha	311	0.9
chr3_38589085_38589252	0.23	Gm43538	predicted gene 43538	25079	0.16
chr11_120543038_120543310	0.23	Mcrip1	MAPK regulated corepressor interacting protein 1	6527	0.06
chr8_70552951_70553110	0.23	Ell	elongation factor RNA polymerase II	13342	0.08
chr13_74769953_74770127	0.23	Cast	calpastatin	550	0.67
chr2_148443567_148443727	0.23	Cd93	CD93 antigen	84	0.97
chr6_31323903_31324093	0.23	2210408F21Rik	RIKEN cDNA 2210408F21 gene	2027	0.28
chr11_106967758_106967936	0.23	Gm11707	predicted gene 11707	5243	0.15
chr6_115480476_115480638	0.23	Gm44079	predicted gene, 44079	15567	0.16
chr4_140770556_140770730	0.23	Padi4	peptidyl arginine deiminase, type IV	3593	0.16
chr4_106564660_106564819	0.23	Dhcr24	24-dehydrocholesterol reductase	3701	0.14
chr15_80720254_80720552	0.23	Gm49512	predicted gene, 49512	8132	0.15
chr4_60424050_60424352	0.23	Mup9	major urinary protein 9	2249	0.23
chr4_148085280_148085458	0.23	Agtrap	angiotensin II, type I receptor-associated protein	593	0.56
chr13_93177685_93177846	0.23	Tent2	terminal nucleotidyltransferase 2	9336	0.2
chr1_10099708_10099862	0.22	Cspp1	centrosome and spindle pole associated protein 1	3921	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rara

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0042891	antibiotic transport(GO:0042891)
0.1	0.2	GO:0040031	snRNA modification(GO:0040031)
0.1	0.2	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.3	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.2	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1	0.2	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	0.2	GO:0006524	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0	0.1	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0	0.2	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.4	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.2	GO:1901628	positive regulation of postsynaptic membrane organization(GO:1901628)
0.0	0.2	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.1	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.1	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:0009157	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.2	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:2000195	negative regulation of female gonad development(GO:2000195)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.1	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.0	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.0	0.1	GO:0015691	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.2	GO:0045618	positive regulation of keratinocyte differentiation(GO:0045618)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:1902004	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0070268	cornification(GO:0070268)
0.0	0.1	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.0	0.0	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:0006598	polyamine catabolic process(GO:0006598)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0061484	hematopoietic stem cell homeostasis(GO:0061484)
0.0	0.0	GO:0009794	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.1	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.0	0.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.4	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0032907	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.3	GO:0045648	positive regulation of erythrocyte differentiation(GO:0045648)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.0	GO:0060164	regulation of timing of neuron differentiation(GO:0060164)
0.0	0.0	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0061198	fungiform papilla formation(GO:0061198)
0.0	0.0	GO:0003133	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0	0.1	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.3	GO:0006379	mRNA cleavage(GO:0006379)
0.0	0.1	GO:1901386	negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0	0.0	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.0	GO:0046645	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.0	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	0.1	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.0	GO:0034635	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0	0.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.1	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0009396	folic acid-containing compound biosynthetic process(GO:0009396)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.0	GO:0015744	succinate transport(GO:0015744)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.0	0.0	GO:0060112	generation of ovulation cycle rhythm(GO:0060112)
0.0	0.0	GO:0051106	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0035740	CD8-positive, alpha-beta T cell proliferation(GO:0035740)
0.0	0.1	GO:0006056	cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0015919	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.3	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0018094	protein polyglycylation(GO:0018094)
0.0	0.1	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.0	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.0	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.0	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.0	GO:0005984	disaccharide metabolic process(GO:0005984)
0.0	0.1	GO:0021615	glossopharyngeal nerve morphogenesis(GO:0021615)
0.0	0.0	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.0	GO:0045626	negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.0	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.0	GO:0002540	leukotriene production involved in inflammatory response(GO:0002540)
0.0	0.1	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.0	0.1	GO:0090049	regulation of cell migration involved in sprouting angiogenesis(GO:0090049)
0.0	0.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.0	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.0	0.0	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.0	0.0	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.1	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.0	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.0	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.1	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.1	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:0038166	angiotensin-activated signaling pathway(GO:0038166)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.2	GO:0002710	negative regulation of T cell mediated immunity(GO:0002710)
0.0	0.1	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:2000598	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.1	GO:1900044	regulation of protein K63-linked ubiquitination(GO:1900044)
0.0	0.0	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:0042536	negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0	0.1	GO:0046697	decidualization(GO:0046697)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.2	GO:0006471	protein ADP-ribosylation(GO:0006471)
0.0	0.1	GO:0034227	tRNA thio-modification(GO:0034227)
0.0	0.0	GO:0060931	sinoatrial node cell development(GO:0060931)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0098903	regulation of membrane repolarization during action potential(GO:0098903)
0.0	0.1	GO:0046133	pyrimidine ribonucleoside catabolic process(GO:0046133)
0.0	0.0	GO:0009169	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.0	GO:0060789	hair follicle placode formation(GO:0060789)
0.0	0.0	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.0	GO:1901491	negative regulation of lymphangiogenesis(GO:1901491)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.1	0.2	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.3	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.2	GO:0070876	SOSS complex(GO:0070876)
0.0	0.2	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0031983	vesicle lumen(GO:0031983)
0.0	0.1	GO:1990393	3M complex(GO:1990393)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.1	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0016593	Cdc73/Paf1 complex(GO:0016593)
0.0	0.1	GO:0031502	dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0	0.0	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.1	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.0	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0	0.0	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0042895	antibiotic transporter activity(GO:0042895)
0.1	0.2	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.2	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.2	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.2	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0016882	cyclo-ligase activity(GO:0016882)
0.0	0.4	GO:0001846	opsonin binding(GO:0001846)
0.0	0.1	GO:0051434	BH3 domain binding(GO:0051434)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.1	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0004720	protein-lysine 6-oxidase activity(GO:0004720)
0.0	0.1	GO:0004945	angiotensin type II receptor activity(GO:0004945)
0.0	0.1	GO:0048030	disaccharide binding(GO:0048030)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0018568	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.1	GO:0018586	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0047498	calcium-dependent phospholipase A2 activity(GO:0047498)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.4	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.0	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.2	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.2	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0008865	fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0	0.1	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.0	GO:0004942	anaphylatoxin receptor activity(GO:0004942)
0.0	0.1	GO:0036137	kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.0	GO:0016715	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0	0.1	GO:0005391	sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0	0.1	GO:0031404	chloride ion binding(GO:0031404)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.1	GO:0019841	retinol binding(GO:0019841)
0.0	0.0	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.0	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0034902	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.2	GO:0022841	potassium ion leak channel activity(GO:0022841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.0	PID NFKAPPAB ATYPICAL PATHWAY	Atypical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.1	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.2	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.2	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.2	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.3	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE	Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline