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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Rbpj

Z-value: 1.61

Motif logo

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Transcription factors associated with Rbpj

Gene Symbol Gene ID Gene Info
Rbpj
ENSMUSG00000039191.6 recombination signal binding protein for immunoglobulin kappa J region

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_53656339_53656508Rbpj106850.2368670.853.4e-02Click!
chr5_53590620_53590774Rbpj2260.9461870.834.2e-02Click!
chr5_53469500_53469671Rbpj34330.2553260.758.8e-02Click!
chr5_53589239_53589555Rbpj8170.6789830.711.1e-01Click!
chr5_53444100_53444263Rbpj219710.1658800.701.2e-01Click!

Activity of the Rbpj motif across conditions

Conditions sorted by the z-value of the Rbpj motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_20989972_20990130 1.02 Rnf138
 ring finger protein 138
 11290
 0.2
chr19_23044990_23045152 0.62 Gm50136
 predicted gene, 50136
 16383
 0.2
chr13_111937084_111937265 0.62 Gm9025
 predicted gene 9025
 52997
 0.09
chr8_123657838_123658224 0.55 Rhou
 ras homolog family member U
 4102
 0.05
chr10_61337817_61337968 0.53 Pald1
 phosphatase domain containing, paladin 1
 4435
 0.15
chr8_117700284_117700470 0.50 Hsd17b2
 hydroxysteroid (17-beta) dehydrogenase 2
 1527
 0.3
chr6_144492068_144492244 0.50 Sox5os2
 SRY (sex determining region Y)-box 5, opposite strand 2
 10931
 0.29
chr4_123427592_123427944 0.49 Gm12924
 predicted gene 12924
 7849
 0.18
chr6_28929316_28929468 0.49 Snd1
 staphylococcal nuclease and tudor domain containing 1
 49349
 0.12
chr1_21305444_21305801 0.49 Gm4956
 predicted gene 4956
 7310
 0.1
chr17_27556354_27556505 0.48 Hmga1
 high mobility group AT-hook 1
 68
 0.51
chr11_58006609_58006789 0.47 Larp1
 La ribonucleoprotein domain family, member 1
 2365
 0.25
chr7_19326476_19326637 0.47 Gm44698
 predicted gene 44698
 6573
 0.07
chr1_136937150_136937320 0.47 Nr5a2
 nuclear receptor subfamily 5, group A, member 2
 3348
 0.29
chr8_36491389_36491571 0.46 Trmt9b
 tRNA methyltransferase 9B
 2289
 0.34
chr2_91264224_91264426 0.44 Arfgap2
 ADP-ribosylation factor GTPase activating protein 2
 649
 0.5
chr1_190076180_190076366 0.44 Gm28172
 predicted gene 28172
 92397
 0.07
chr11_103021982_103022133 0.42 Dcakd
 dephospho-CoA kinase domain containing
 4889
 0.13
chr3_98295816_98295967 0.42 Gm43189
 predicted gene 43189
 8903
 0.15
chr7_6696462_6696626 0.41 Zim1
 zinc finger, imprinted 1
 94
 0.95
chr12_102453656_102453840 0.41 Gm30198
 predicted gene, 30198
 6420
 0.17
chr13_92609818_92609992 0.41 Serinc5
 serine incorporator 5
 1186
 0.52
chr2_128731575_128731758 0.40 Gm14011
 predicted gene 14011
 22039
 0.13
chr10_11615264_11615424 0.39 Gm9797
 predicted pseudogene 9797
 6046
 0.22
chr15_100666435_100666616 0.39 Bin2
 bridging integrator 2
 2980
 0.13
chr6_142708472_142708687 0.39 Abcc9
 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
 6264
 0.22
chr11_70585533_70585714 0.38 Mink1
 misshapen-like kinase 1 (zebrafish)
 13365
 0.07
chr17_31871058_31871230 0.38 Sik1
 salt inducible kinase 1
 15340
 0.14
chr8_70219826_70219982 0.38 Armc6
 armadillo repeat containing 6
 2386
 0.16
chr19_42601924_42602199 0.37 Loxl4
 lysyl oxidase-like 4
 1260
 0.45
chr1_106189902_106190053 0.37 Phlpp1
 PH domain and leucine rich repeat protein phosphatase 1
 18225
 0.16
chr1_193270900_193271248 0.36 G0s2
 G0/G1 switch gene 2
 2143
 0.16
chr4_54874667_54875024 0.36 Gm12479
 predicted gene 12479
 21717
 0.23
chr7_100908136_100908439 0.36 Arhgef17
 Rho guanine nucleotide exchange factor (GEF) 17
 13597
 0.13
chr1_157012797_157012985 0.36 Gm10531
 predicted gene 10531
 30656
 0.14
chr2_154613231_154613406 0.36 Zfp341
 zinc finger protein 341
 21
 0.6
chr9_102864196_102864634 0.36 Ryk
 receptor-like tyrosine kinase
 4651
 0.18
chr4_86664611_86664778 0.36 Plin2
 perilipin 2
 1031
 0.52
chr9_21032221_21032372 0.35 Mir1900
 microRNA 1900
 32
 0.44
chr8_120244102_120244267 0.35 Gse1
 genetic suppressor element 1, coiled-coil protein
 15728
 0.17
chr2_31135715_31135955 0.35 Fnbp1
 formin binding protein 1
 5967
 0.16
chr17_80061203_80061420 0.35 Hnrnpll
 heterogeneous nuclear ribonucleoprotein L-like
 824
 0.55
chr2_38379077_38379228 0.35 Gm13584
 predicted gene 13584
 15172
 0.14
chr8_11002584_11002773 0.35 9530052E02Rik
 RIKEN cDNA 9530052E02 gene
 5172
 0.14
chr8_83582345_83582520 0.34 Gm45823
 predicted gene 45823
 3093
 0.12
chr6_36280777_36280955 0.34 9330158H04Rik
 RIKEN cDNA 9330158H04 gene
 6510
 0.29
chr5_112294789_112294953 0.34 Tpst2
 protein-tyrosine sulfotransferase 2
 6109
 0.12
chr8_117357893_117358044 0.34 Cmip
 c-Maf inducing protein
 8798
 0.25
chr8_93959067_93959388 0.34 Gnao1
 guanine nucleotide binding protein, alpha O
 3617
 0.19
chr15_102181335_102181499 0.34 Csad
 cysteine sulfinic acid decarboxylase
 1556
 0.24
chr16_37431973_37432137 0.34 Stxbp5l
 syntaxin binding protein 5-like
 47093
 0.13
chr4_148147807_148147968 0.34 Mir7022
 microRNA 7022
 891
 0.36
chr8_13038384_13038564 0.33 F10
 coagulation factor X
 636
 0.54
chr9_65036564_65036722 0.33 Dpp8
 dipeptidylpeptidase 8
 3865
 0.18
chr18_69690243_69690422 0.33 Tcf4
 transcription factor 4
 7952
 0.3
chr13_63929441_63929609 0.33 Gm7695
 predicted gene 7695
 16996
 0.18
chr4_7143814_7143981 0.32 Gm11804
 predicted gene 11804
 104383
 0.08
chr2_44114387_44114618 0.32 Arhgap15os
 Rho GTPase activating protein 15, opposite strand
 49178
 0.17
chr14_79514360_79514523 0.32 Elf1
 E74-like factor 1
 1233
 0.43
chr7_68606375_68606542 0.32 Gm44887
 predicted gene 44887
 7604
 0.22
chr5_121400646_121400949 0.32 Gm43420
 predicted gene 43420
 1861
 0.18
chr18_80237311_80237611 0.31 Hsbp1l1
 heat shock factor binding protein 1-like 1
 628
 0.57
chr13_38086772_38086930 0.31 Gm27387
 predicted gene, 27387
 649
 0.69
chr5_142440070_142440526 0.31 Ap5z1
 adaptor-related protein complex 5, zeta 1 subunit
 23646
 0.17
chr1_51909329_51909480 0.31 Myo1b
 myosin IB
 2088
 0.24
chr15_25942169_25942359 0.31 Retreg1
 reticulophagy regulator 1
 415
 0.85
chr5_126954306_126954487 0.31 Gm42955
 predicted gene 42955
 65831
 0.11
chr6_28896982_28897268 0.31 Snd1
 staphylococcal nuclease and tudor domain containing 1
 17082
 0.2
chr8_83582597_83582758 0.30 Gm45823
 predicted gene 45823
 2848
 0.13
chr9_123492299_123492489 0.30 Limd1
 LIM domains containing 1
 11784
 0.17
chr3_145592253_145592420 0.30 Znhit6
 zinc finger, HIT type 6
 3532
 0.25
chr11_45877552_45877727 0.30 Clint1
 clathrin interactor 1
 4758
 0.18
chr11_114867107_114867285 0.30 Gprc5c
 G protein-coupled receptor, family C, group 5, member C
 2704
 0.19
chr2_61474961_61475340 0.30 Gm22338
 predicted gene, 22338
 17616
 0.26
chr5_72763116_72763280 0.29 Txk
 TXK tyrosine kinase
 10421
 0.15
chr17_5295996_5296161 0.29 Gm29050
 predicted gene 29050
 92685
 0.08
chr15_7070249_7070660 0.29 Lifr
 LIF receptor alpha
 20160
 0.25
chr17_27817796_27817959 0.29 Ilrun
 inflammation and lipid regulator with UBA-like and NBR1-like domains
 2575
 0.18
chr7_16047828_16047993 0.28 Bicra
 BRD4 interacting chromatin remodeling complex associated protein
 11
 0.97
chr6_31263686_31264023 0.28 2210408F21Rik
 RIKEN cDNA 2210408F21 gene
 13994
 0.16
chr8_93332780_93333003 0.28 Ces1g
 carboxylesterase 1G
 4417
 0.17
chr7_6343656_6343820 0.28 Gm3854
 predicted gene 3854
 21
 0.77
chr11_4661332_4661649 0.28 Ascc2
 activating signal cointegrator 1 complex subunit 2
 23743
 0.12
chr6_114866683_114866890 0.28 Vgll4
 vestigial like family member 4
 2029
 0.33
chr15_100625350_100625569 0.28 Dazap2
 DAZ associated protein 2
 9127
 0.08
chr18_36713491_36713783 0.28 Cd14
 CD14 antigen
 13101
 0.07
chr19_4719341_4719664 0.27 Sptbn2
 spectrin beta, non-erythrocytic 2
 1577
 0.24
chr5_93250297_93250457 0.27 Ccng2
 cyclin G2
 16880
 0.14
chr7_127967101_127967258 0.27 Fus
 fused in sarcoma
 278
 0.77
chr2_133552164_133552315 0.27 Bmp2
 bone morphogenetic protein 2
 80
 0.97
chr2_93775482_93775671 0.27 Gm13818
 predicted gene 13818
 18994
 0.17
chr19_6991850_6992452 0.27 Dnajc4
 DnaJ heat shock protein family (Hsp40) member C4
 121
 0.89
chr7_112237962_112238160 0.27 Mical2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 12171
 0.27
chr9_115481085_115481255 0.27 Gm5921
 predicted gene 5921
 42589
 0.13
chr4_134488308_134488479 0.26 Gm13250
 predicted gene 13250
 4829
 0.11
chr11_29613290_29613486 0.26 Gm12091
 predicted gene 12091
 10775
 0.13
chr17_86539829_86540339 0.26 Gm10309
 predicted gene 10309
 34852
 0.18
chr5_146974799_146974984 0.26 Mtif3
 mitochondrial translational initiation factor 3
 11091
 0.17
chr6_124694855_124695031 0.26 Lpcat3
 lysophosphatidylcholine acyltransferase 3
 6476
 0.07
chr5_65349405_65349570 0.26 Klb
 klotho beta
 1079
 0.38
chr14_100284919_100285099 0.26 Klf12
 Kruppel-like factor 12
 330
 0.83
chrX_37085164_37085323 0.26 Rpl39
 ribosomal protein L39
 77
 0.94
chr12_111443408_111443817 0.26 Tnfaip2
 tumor necrosis factor, alpha-induced protein 2
 712
 0.55
chr11_7536835_7536986 0.26 Gm11986
 predicted gene 11986
 246536
 0.02
chr2_90503158_90503454 0.26 4933423P22Rik
 RIKEN cDNA 4933423P22 gene
 24056
 0.16
chr9_10340859_10341010 0.25 Gm25086
 predicted gene, 25086
 45778
 0.15
chr10_66933753_66933946 0.25 Gm26576
 predicted gene, 26576
 13547
 0.16
chr14_30906121_30906307 0.25 Itih4
 inter alpha-trypsin inhibitor, heavy chain 4
 7053
 0.11
chr19_7090027_7090210 0.25 AC109619.1
 novel transcript, antisense to Macrod1
 1697
 0.24
chr19_21914078_21914469 0.25 Ldhb-ps
 lactate dehydrogenase B, pseudogene
 23107
 0.18
chr5_117985838_117985989 0.25 Fbxo21
 F-box protein 21
 6589
 0.15
chr17_34586879_34587070 0.25 Notch4
 notch 4
 29
 0.91
chr1_164435096_164435776 0.25 Atp1b1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 8283
 0.15
chr16_77360217_77360390 0.25 Gm37466
 predicted gene, 37466
 21647
 0.13
chr10_93161593_93161779 0.25 Cdk17
 cyclin-dependent kinase 17
 796
 0.5
chrX_16815855_16816045 0.25 Maob
 monoamine oxidase B
 1325
 0.59
chr12_85785184_85785363 0.24 Flvcr2
 feline leukemia virus subgroup C cellular receptor 2
 10443
 0.16
chr5_35751138_35751297 0.24 Ablim2
 actin-binding LIM protein 2
 6663
 0.18
chr5_130256839_130256998 0.24 Tyw1
 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
 117
 0.93
chr16_90143819_90143995 0.24 Tiam1
 T cell lymphoma invasion and metastasis 1
 138
 0.96
chr14_59505972_59506134 0.24 Cab39l
 calcium binding protein 39-like
 27237
 0.17
chr7_25238448_25238634 0.24 Gsk3a
 glycogen synthase kinase 3 alpha
 690
 0.45
chr11_63851241_63851480 0.24 Hmgb1-ps3
 high mobility group box 1, pseudogene 3
 4542
 0.26
chr10_62216958_62217109 0.24 Tspan15
 tetraspanin 15
 14218
 0.15
chr7_131556667_131556855 0.24 Hmx2
 H6 homeobox 2
 2700
 0.19
chr4_109140391_109140554 0.24 Osbpl9
 oxysterol binding protein-like 9
 16138
 0.21
chr17_46995065_46995238 0.24 Ubr2
 ubiquitin protein ligase E3 component n-recognin 2
 15328
 0.16
chr9_66795028_66795465 0.24 Aph1b
 aph1 homolog B, gamma secretase subunit
 130
 0.93
chr8_88863392_88863746 0.24 Gm45504
 predicted gene 45504
 495
 0.85
chr19_36834098_36834270 0.24 Tnks2
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
 48
 0.98
chr9_88438974_88439140 0.24 Snx14
 sorting nexin 14
 99
 0.95
chr7_44670891_44671049 0.24 Myh14
 myosin, heavy polypeptide 14
 127
 0.92
chr1_119661376_119661532 0.24 Epb41l5
 erythrocyte membrane protein band 4.1 like 5
 12454
 0.16
chr8_126736201_126736366 0.24 Gm45805
 predicted gene 45805
 22051
 0.23
chr1_21232096_21232271 0.23 Gm38224
 predicted gene, 38224
 2539
 0.18
chr10_125354951_125355118 0.23 Slc16a7
 solute carrier family 16 (monocarboxylic acid transporters), member 7
 12855
 0.22
chr19_53140710_53140861 0.23 Add3
 adducin 3 (gamma)
 268
 0.88
chr8_60890550_60890715 0.23 Hpf1
 histone PARylation factor 1
 143
 0.96
chr11_113725569_113725747 0.23 Cdc42ep4
 CDC42 effector protein (Rho GTPase binding) 4
 13664
 0.13
chr16_23978554_23978740 0.23 Bcl6
 B cell leukemia/lymphoma 6
 6267
 0.18
chr6_88743999_88744163 0.23 Gm43999
 predicted gene, 43999
 1354
 0.31
chr5_122526542_122526845 0.23 Gm22965
 predicted gene, 22965
 19904
 0.09
chr11_28584268_28584419 0.23 Ccdc85a
 coiled-coil domain containing 85A
 19
 0.99
chr8_8994570_8994800 0.23 Gm44515
 predicted gene 44515
 61986
 0.12
chr9_77753424_77753607 0.23 Gclc
 glutamate-cysteine ligase, catalytic subunit
 1020
 0.45
chr11_86916528_86916698 0.23 Ypel2
 yippee like 2
 55411
 0.11
chr19_10073210_10073809 0.23 Fads2
 fatty acid desaturase 2
 2322
 0.22
chr8_25793840_25794009 0.23 Lsm1
 LSM1 homolog, mRNA degradation associated
 8337
 0.1
chr2_12148001_12148165 0.22 Itga8
 integrin alpha 8
 15531
 0.2
chr14_76152803_76153117 0.22 Nufip1
 nuclear fragile X mental retardation protein interacting protein 1
 42069
 0.14
chr15_10248990_10249545 0.22 Prlr
 prolactin receptor
 293
 0.94
chr10_59475055_59475224 0.22 Mcu
 mitochondrial calcium uniporter
 16979
 0.18
chr2_164785184_164785412 0.22 Snx21
 sorting nexin family member 21
 525
 0.53
chr9_69323922_69324079 0.22 Rora
 RAR-related orphan receptor alpha
 34318
 0.15
chr10_20104280_20104431 0.22 Map3k5
 mitogen-activated protein kinase kinase kinase 5
 4830
 0.24
chr16_30065187_30065349 0.22 Hes1
 hes family bHLH transcription factor 1
 72
 0.97
chrX_12135920_12136079 0.22 Bcor
 BCL6 interacting corepressor
 7599
 0.26
chr2_59726132_59726380 0.22 Tanc1
 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
 16546
 0.26
chr5_144333150_144333429 0.22 Dmrt1i
 Dmrt1 interacting ncRNA
 24634
 0.13
chr19_40464469_40464658 0.22 Sorbs1
 sorbin and SH3 domain containing 1
 13173
 0.21
chr4_11861590_11861758 0.22 Gm25002
 predicted gene, 25002
 87213
 0.07
chr6_35253418_35253775 0.22 1810058I24Rik
 RIKEN cDNA 1810058I24 gene
 864
 0.54
chr11_17258171_17258606 0.22 C1d
 C1D nuclear receptor co-repressor
 700
 0.69
chr4_95141392_95141560 0.21 Gm28096
 predicted gene 28096
 10264
 0.16
chr11_109485510_109486095 0.21 Arsg
 arylsulfatase G
 196
 0.91
chr11_115824988_115825141 0.21 Llgl2
 LLGL2 scribble cell polarity complex component
 1006
 0.35
chr5_43869261_43869583 0.21 Cd38
 CD38 antigen
 562
 0.61
chr10_25595963_25596295 0.21 Gm36908
 predicted gene, 36908
 25434
 0.15
chr6_57506758_57506926 0.21 Ppm1k
 protein phosphatase 1K (PP2C domain containing)
 8765
 0.14
chr19_47337853_47338021 0.21 Sh3pxd2a
 SH3 and PX domains 2A
 23186
 0.17
chr12_28623362_28623536 0.21 Colec11
 collectin sub-family member 11
 72
 0.96
chr8_119417171_119417322 0.21 Osgin1
 oxidative stress induced growth inhibitor 1
 16878
 0.13
chr4_126181292_126181458 0.21 Thrap3
 thyroid hormone receptor associated protein 3
 1228
 0.32
chr8_82689441_82689600 0.21 Gm9655
 predicted gene 9655
 58096
 0.13
chr4_82406927_82407107 0.21 n-R5s188
 nuclear encoded rRNA 5S 188
 32393
 0.21
chr2_126373873_126374024 0.21 Atp8b4
 ATPase, class I, type 8B, member 4
 117605
 0.05
chr15_78450182_78450345 0.21 Tmprss6
 transmembrane serine protease 6
 5884
 0.11
chr16_33062247_33062405 0.21 Lmln
 leishmanolysin-like (metallopeptidase M8 family)
 195
 0.9
chr4_125065950_125066101 0.21 Dnali1
 dynein, axonemal, light intermediate polypeptide 1
 322
 0.66
chr4_128621016_128621181 0.21 Tlr12
 toll-like receptor 12
 2479
 0.24
chr10_81326957_81327144 0.21 Tbxa2r
 thromboxane A2 receptor
 1681
 0.13
chr13_74166717_74166944 0.21 Exoc3
 exocyst complex component 3
 7617
 0.19
chr11_75190453_75190617 0.21 Dph1
 diphthamide biosynthesis 1
 16
 0.95
chr1_73188866_73189036 0.21 Gm38106
 predicted gene, 38106
 20472
 0.23
chr11_58914378_58914796 0.21 Btnl10
 butyrophilin-like 10
 3321
 0.09
chr10_99215027_99215178 0.20 Gm34574
 predicted gene, 34574
 7964
 0.12
chr7_112353137_112353298 0.20 Mical2
 microtubule associated monooxygenase, calponin and LIM domain containing 2
 3823
 0.33
chr17_10237978_10238400 0.20 Qk
 quaking
 24615
 0.24
chr5_8961694_8961940 0.20 Abcb4
 ATP-binding cassette, sub-family B (MDR/TAP), member 4
 3265
 0.17
chr6_13871418_13871584 0.20 2610001J05Rik
 RIKEN cDNA 2610001J05 gene
 17
 0.5
chr5_150195920_150196236 0.20 Fry
 FRY microtubule binding protein
 388
 0.88
chr11_19920515_19920734 0.20 Spred2
 sprouty-related EVH1 domain containing 2
 3751
 0.33
chr17_12415417_12415751 0.20 Plg
 plasminogen
 36925
 0.12
chr17_85037271_85037422 0.20 Slc3a1
 solute carrier family 3, member 1
 8970
 0.19
chr3_115635601_115635754 0.20 S1pr1
 sphingosine-1-phosphate receptor 1
 79395
 0.09
chr2_34154899_34155111 0.20 Gm38389
 predicted gene, 38389
 43561
 0.15
chr15_76722928_76723137 0.20 C030006K11Rik
 RIKEN cDNA C030006K11 gene
 353
 0.62
chr19_40630689_40630866 0.20 Gm8783
 predicted pseudogene 8783
 8317
 0.12
chr17_12402018_12402192 0.20 Plg
 plasminogen
 23446
 0.15
chr1_52113713_52114086 0.20 Gm31812
 predicted gene, 31812
 148
 0.93

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Rbpj

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.1 0.3 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.2 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 0.2 GO:1990791 dorsal root ganglion development(GO:1990791)
0.1 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.2 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.2 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.2 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.2 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.2 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.2 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0045472 response to ether(GO:0045472)
0.0 0.1 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.1 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.2 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.2 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:1901679 nucleotide transmembrane transport(GO:1901679)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.1 GO:0009240 isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.1 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.2 GO:0019673 GDP-mannose metabolic process(GO:0019673)
0.0 0.2 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.2 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.2 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.1 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.1 GO:0043133 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0 0.1 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.0 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.0 GO:2001198 regulation of dendritic cell differentiation(GO:2001198)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.0 0.1 GO:0061643 chemorepulsion of axon(GO:0061643)
0.0 0.0 GO:0033668 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.1 GO:0071225 cellular response to muramyl dipeptide(GO:0071225)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.0 0.1 GO:0060066 oviduct development(GO:0060066)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.3 GO:0033194 response to hydroperoxide(GO:0033194)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0070584 mitochondrion morphogenesis(GO:0070584)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.0 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:2001286 regulation of caveolin-mediated endocytosis(GO:2001286)
0.0 0.2 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.2 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.0 0.1 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.0 0.0 GO:0043307 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil activation(GO:0043307) eosinophil degranulation(GO:0043308)
0.0 0.1 GO:0003241 growth involved in heart morphogenesis(GO:0003241)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.0 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.0 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.0 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0 0.0 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.0 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.0 GO:0007227 signal transduction downstream of smoothened(GO:0007227)
0.0 0.1 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.0 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.0 GO:0010748 negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0 0.0 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.0 0.1 GO:0052405 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.0 GO:0010911 regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0 0.1 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.0 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.0 0.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.0 GO:0060375 regulation of mast cell differentiation(GO:0060375)
0.0 0.0 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0006787 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0 0.0 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.0 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.0 0.0 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.0 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.0 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.1 GO:0016199 axon midline choice point recognition(GO:0016199)
0.0 0.0 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.0 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.2 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.0 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.1 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:0071332 response to fructose(GO:0009750) cellular response to fructose stimulus(GO:0071332)
0.0 0.0 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.0 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.0 0.1 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.0 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0071404 cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0 0.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.0 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.1 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.0 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 0.1 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.0 GO:0071394 cellular response to testosterone stimulus(GO:0071394)
0.0 0.0 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.0 GO:0009106 lipoate metabolic process(GO:0009106)
0.0 0.0 GO:0086023 adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.0 0.2 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.1 GO:0008054 negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0 0.0 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.0 GO:1904714 regulation of chaperone-mediated autophagy(GO:1904714)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.1 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0 0.0 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.2 GO:0097513 myosin II filament(GO:0097513)
0.1 0.2 GO:0097443 sorting endosome(GO:0097443)
0.1 0.2 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0035838 growing cell tip(GO:0035838)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.3 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.2 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.0 GO:0005608 laminin-3 complex(GO:0005608)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 0.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.1 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.0 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.0 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.1 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.0 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.0 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.0 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.0 GO:0031428 box C/D snoRNP complex(GO:0031428)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.2 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.2 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.1 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0034889 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.0 GO:0003996 acyl-CoA ligase activity(GO:0003996)
0.0 0.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.1 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0070538 oleic acid binding(GO:0070538)
0.0 0.1 GO:0051733 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.1 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0034791 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.0 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.0 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.0 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.2 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.0 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.0 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.0 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.0 0.0 GO:0034235 GPI anchor binding(GO:0034235)
0.0 0.0 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.0 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:1990381 ubiquitin-specific protease binding(GO:1990381)
0.0 0.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.0 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.0 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.0 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.3 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.3 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.1 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.1 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME SIGNALING BY NOTCH4 Genes involved in Signaling by NOTCH4
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.0 REACTOME PI3K AKT ACTIVATION Genes involved in PI3K/AKT activation
0.0 0.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins