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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Rfx3_Rfx1_Rfx4

Z-value: 4.74

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Transcription factors associated with Rfx3_Rfx1_Rfx4

Gene Symbol	Gene ID	Gene Info
Rfx3 Ensembl NCBI MGI UniProt	ENSMUSG00000040929.10	regulatory factor X, 3 (influences HLA class II expression)
Rfx1 Ensembl NCBI MGI UniProt	ENSMUSG00000031706.6	regulatory factor X, 1 (influences HLA class II expression)
Rfx4 Ensembl NCBI MGI UniProt	ENSMUSG00000020037.9	regulatory factor X, 4 (influences HLA class II expression)

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr8_84066504_84066866	Rfx1	149	0.785304	0.71	1.2e-01	Click!
chr8_84066228_84066423	Rfx1	509	0.434141	-0.23	6.6e-01	Click!
chr19_28011047_28011201	Rfx3	16	0.978136	0.91	1.3e-02	Click!
chr19_27780112_27780288	Rfx3	56646	0.132323	-0.80	5.6e-02	Click!
chr19_28011850_28012051	Rfx3	784	0.644606	-0.73	9.6e-02	Click!
chr19_28010182_28010333	Rfx3	533	0.779462	-0.62	1.9e-01	Click!
chr19_28011552_28011713	Rfx3	466	0.816498	0.54	2.7e-01	Click!
chr10_84707367_84707588	Rfx4	48585	0.117999	0.85	3.2e-02	Click!
chr10_84872038_84872201	Rfx4	33971	0.162241	0.77	7.5e-02	Click!
chr10_84757574_84757782	Rfx4	1616	0.434985	0.76	8.2e-02	Click!
chr10_84701256_84701556	Rfx4	54656	0.103014	0.75	8.5e-02	Click!
chr10_84707165_84707334	Rfx4	48813	0.117411	0.72	1.0e-01	Click!

Activity of the Rfx3_Rfx1_Rfx4 motif across conditions

Conditions sorted by the z-value of the Rfx3_Rfx1_Rfx4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_100265981_100266134	4.72	Gm10432	predicted gene 10432	10552	0.16
chr11_67549406_67549557	4.27	Gas7	growth arrest specific 7	2028	0.38
chr1_74807002_74807292	4.08	Wnt10a	wingless-type MMTV integration site family, member 10A	13784	0.11
chr11_70562367_70562529	3.04	Mink1	misshapen-like kinase 1 (zebrafish)	433	0.62
chr13_119599160_119599326	2.68	Tmem267	transmembrane protein 267	7407	0.14
chr6_34901958_34902109	2.64	Wdr91	WD repeat domain 91	8530	0.13
chr19_53852730_53852886	2.61	Rbm20	RNA binding motif protein 20	9598	0.15
chr16_43979287_43979438	2.60	Zdhhc23	zinc finger, DHHC domain containing 23	200	0.93
chr18_46337024_46337197	2.51	4930415P13Rik	RIKEN cDNA 4930415P13 gene	3319	0.19
chr10_79767495_79767669	2.50	Rnf126	ring finger protein 126	630	0.45
chr2_10276297_10276461	2.46	Sfmbt2	Scm-like with four mbt domains 2	94131	0.02
chr10_93525725_93526217	2.36	Amdhd1	amidohydrolase domain containing 1	14062	0.13
chr6_91488990_91489149	2.33	Tmem43	transmembrane protein 43	12469	0.1
chr12_8447841_8448015	2.32	Gm48076	predicted gene, 48076	6990	0.17
chr12_36207522_36207673	2.26	Lrrc72	leucine rich repeat containing 72	10605	0.14
chr14_20969178_20969340	2.18	Vcl	vinculin	39861	0.15
chr3_131471046_131471225	2.16	Sgms2	sphingomyelin synthase 2	19344	0.22
chr12_100186576_100186727	2.16	Gm48296	predicted gene, 48296	360	0.76
chr6_86193078_86193250	2.13	Tgfa	transforming growth factor alpha	2059	0.28
chr2_30658504_30658675	2.13	Gm14486	predicted gene 14486	11319	0.15
chr5_135674889_135675201	2.00	Por	P450 (cytochrome) oxidoreductase	460	0.66
chr14_20208430_20208743	1.99	Gm48395	predicted gene, 48395	6916	0.12
chr1_177531902_177532053	1.91	Gm37280	predicted gene, 37280	62545	0.09
chr14_62880064_62880380	1.86	n-R5s47	nuclear encoded rRNA 5S 47	10508	0.13
chr1_52456624_52456777	1.81	Nab1	Ngfi-A binding protein 1	10357	0.16
chr11_116103998_116104299	1.79	Trim47	tripartite motif-containing 47	2935	0.13
chr8_113125682_113125850	1.78	Gm10280	predicted gene 10280	58504	0.16
chr4_152108300_152108506	1.77	Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	674	0.57
chr13_119597573_119597724	1.76	Tmem267	transmembrane protein 267	9002	0.14
chr2_102944085_102944371	1.75	Cd44	CD44 antigen	42563	0.15
chr1_53823867_53824094	1.73	Hecw2	HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2	17191	0.16
chr18_38190654_38190820	1.73	Pcdh1	protocadherin 1	12426	0.13
chr5_107413821_107414114	1.73	Ephx4	epoxide hydrolase 4	8182	0.1
chr19_8788660_8788811	1.72	Gm50131	predicted gene, 50131	1729	0.1
chr2_135259291_135259442	1.69	Plcb1	phospholipase C, beta 1	10193	0.27
chr4_43031709_43031892	1.67	Stoml2	stomatin (Epb7.2)-like 2	90	0.94
chr11_105944162_105944330	1.67	Cyb561	cytochrome b-561	107	0.86
chr15_31536046_31536238	1.64	Marchf6	membrane associated ring-CH-type finger 6	5089	0.14
chr11_121741582_121741733	1.62	Metrnl	meteorin, glial cell differentiation regulator-like	38894	0.12
chr12_103827767_103827951	1.62	Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	2514	0.15
chrX_170005299_170005472	1.62	Erdr1	erythroid differentiation regulator 1	4274	0.18
chr7_80187076_80187238	1.61	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	279	0.84
chr17_5139034_5139215	1.60	Gm15599	predicted gene 15599	27014	0.23
chr2_168198397_168198914	1.59	Adnp	activity-dependent neuroprotective protein	8054	0.11
chr13_119601172_119601469	1.59	Tmem267	transmembrane protein 267	5330	0.15
chr13_93234760_93234922	1.59	Tent2	terminal nucleotidyltransferase 2	42456	0.12
chr10_25621100_25621500	1.58	Gm36908	predicted gene, 36908	263	0.92
chrY_90777171_90777322	1.58	Gm47283	predicted gene, 47283	7492	0.18
chr18_3839883_3840055	1.57	Rpl7a-ps6	ribosomal protein L7A, pseudogene 6	18611	0.24
chrX_74645728_74645904	1.57	Gm5640	predicted gene 5640	181	0.89
chr2_85050098_85050267	1.57	Tnks1bp1	tankyrase 1 binding protein 1	278	0.85
chr5_139797862_139798025	1.56	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	429	0.75
chrX_100700542_100700698	1.55	Kif4	kinesin family member 4	11507	0.14
chr7_68748458_68748624	1.55	Arrdc4	arrestin domain containing 4	647	0.76
chr18_25645966_25646123	1.52	Gm3227	predicted gene 3227	48554	0.16
chr9_4372230_4372403	1.51	Gm23992	predicted gene, 23992	981	0.54
chr2_115036372_115036535	1.51	Gm13973	predicted gene 13973	859	0.72
chr6_118955876_118956042	1.51	Gm25905	predicted gene, 25905	121059	0.06
chr10_20285755_20285929	1.51	Gm48249	predicted gene, 48249	784	0.5
chr3_141411390_141411562	1.50	Unc5c	unc-5 netrin receptor C	53740	0.15
chrX_170002838_170002989	1.50	Erdr1	erythroid differentiation regulator 1	6746	0.16
chr11_119834463_119834628	1.50	Rptoros	regulatory associated protein of MTOR, complex 1, opposite strand	180	0.94
chr7_49422973_49423142	1.50	Nav2	neuron navigator 2	27703	0.2
chr3_95653729_95653883	1.47	Mcl1	myeloid cell leukemia sequence 1	4982	0.11
chr15_6390774_6390944	1.47	Dab2	disabled 2, mitogen-responsive phosphoprotein	739	0.72
chr17_33555343_33555494	1.46	Myo1f	myosin IF	289	0.87
chr2_174858524_174858697	1.44	Gm14616	predicted gene 14616	2321	0.26
chr2_170287488_170287839	1.44	Gm14270	predicted gene 14270	2628	0.33
chr7_35086664_35086854	1.44	Gm35611	predicted gene, 35611	77	0.93
chr11_109559331_109559545	1.43	Arsg	arylsulfatase G	15684	0.15
chr10_59466713_59466931	1.42	Mcu	mitochondrial calcium uniporter	8662	0.2
chrY_90775817_90775968	1.41	Gm47283	predicted gene, 47283	8846	0.18
chr8_117097600_117097751	1.41	Bco1	beta-carotene oxygenase 1	1677	0.32
chr19_61054678_61054829	1.41	Gm22520	predicted gene, 22520	41208	0.13
chr6_91972206_91972611	1.41	Fgd5	FYVE, RhoGEF and PH domain containing 5	6470	0.15
chr10_39133860_39134019	1.40	Fam229b	family with sequence similarity 229, member B	25	0.5
chr3_90084119_90084300	1.40	Tpm3	tropomyosin 3, gamma	2162	0.14
chr4_86436431_86436595	1.40	Gm12550	predicted gene 12550	5828	0.26
chr10_99263084_99263251	1.39	Dusp6	dual specificity phosphatase 6	64	0.95
chr6_62889290_62889455	1.39	Gm5001	predicted gene 5001	39774	0.18
chr2_25568780_25568931	1.38	Mamdc4	MAM domain containing 4	260	0.76
chrX_43495267_43495434	1.35	Gm14588	predicted gene 14588	21396	0.21
chr11_51832537_51832709	1.32	Jade2	jade family PHD finger 2	24502	0.15
chr8_84198463_84198651	1.32	Gm26887	predicted gene, 26887	890	0.27
chr13_52847569_52847745	1.31	Auh	AU RNA binding protein/enoyl-coenzyme A hydratase	65289	0.12
chr1_138136532_138136713	1.31	Ptprc	protein tyrosine phosphatase, receptor type, C	15902	0.15
chr13_60110561_60110731	1.30	A530065N20Rik	RIKEN cDNA A530046M15 gene	1531	0.37
chr19_4181960_4182117	1.28	Tbc1d10c	TBC1 domain family, member 10c	3494	0.06
chr6_99500973_99501141	1.28	Gm22328	predicted gene, 22328	16355	0.19
chr8_94962283_94962456	1.27	Gm10286	predicted gene 10286	7385	0.12
chr4_148837167_148837337	1.27	Casz1	castor zinc finger 1	32787	0.16
chr12_111726240_111726395	1.26	Gm15995	predicted gene 15995	75	0.94
chr13_34076543_34076696	1.25	Tubb2a	tubulin, beta 2A class IIA	1388	0.27
chr4_128635594_128635931	1.25	Gm12958	predicted gene 12958	1709	0.31
chr8_22124586_22124925	1.25	Nek5	NIMA (never in mitosis gene a)-related expressed kinase 5	283	0.87
chr3_122476787_122476946	1.24	Bcar3	breast cancer anti-estrogen resistance 3	6857	0.15
chr13_37514323_37514524	1.24	Gm29590	predicted gene 29590	4705	0.12
chr10_75037046_75037206	1.23	Rab36	RAB36, member RAS oncogene family	37	0.97
chr5_139365138_139365294	1.23	Mir339	microRNA 339	4529	0.13
chr7_130683570_130683742	1.23	Tacc2	transforming, acidic coiled-coil containing protein 2	8900	0.19
chr10_25621562_25621727	1.23	Gm36908	predicted gene, 36908	81	0.97
chr4_82291564_82291726	1.22	n-R5s188	nuclear encoded rRNA 5S 188	147765	0.04
chr7_13054687_13054851	1.22	Mzf1	myeloid zinc finger 1	5	0.94
chr8_120292212_120292567	1.21	Gse1	genetic suppressor element 1, coiled-coil protein	63933	0.09
chr5_77372890_77373045	1.21	Gm34648	predicted gene, 34648	13632	0.14
chr11_70104007_70104224	1.21	Asgr2	asialoglycoprotein receptor 2	6423	0.1
chr3_37769304_37769512	1.20	Gm42921	predicted gene 42921	8371	0.13
chr15_73561237_73561449	1.20	Dennd3	DENN/MADD domain containing 3	3519	0.23
chr2_30693310_30693464	1.19	Gm14486	predicted gene 14486	15376	0.14
chrX_38217072_38217230	1.19	Mir3110	microRNA 3110	6710	0.15
chr4_55047383_55047553	1.18	Zfp462	zinc finger protein 462	35988	0.17
chr4_137377515_137377675	1.17	2810405F17Rik	RIKEN cDNA 2810405F17 gene	10787	0.12
chr7_130648140_130648330	1.17	Tacc2	transforming, acidic coiled-coil containing protein 2	1992	0.31
chr2_163502322_163502499	1.16	Hnf4a	hepatic nuclear factor 4, alpha	4398	0.13
chr17_86900977_86901140	1.16	Tmem247	transmembrane protein 247	16290	0.14
chr4_155371101_155371373	1.16	Prkcz	protein kinase C, zeta	9876	0.13
chr2_145748022_145748197	1.16	Rin2	Ras and Rab interactor 2	36625	0.17
chr4_55042640_55042808	1.15	Zfp462	zinc finger protein 462	31244	0.19
chr8_123212852_123213049	1.15	Spata33	spermatogenesis associated 33	52	0.66
chr1_152556618_152556802	1.14	Rgl1	ral guanine nucleotide dissociation stimulator,-like 1	3666	0.31
chr8_71569528_71569691	1.14	Slc27a1	solute carrier family 27 (fatty acid transporter), member 1	70	0.92
chr2_28699654_28699805	1.14	Spaca9	sperm acrosome associated 9	2	0.88
chr8_84979994_84980199	1.14	Junb	jun B proto-oncogene	1378	0.16
chr12_25098846_25099021	1.13	Id2	inhibitor of DNA binding 2	1793	0.31
chr9_124424078_124424238	1.13	Ppp2r3d	protein phosphatase 2 (formerly 2A), regulatory subunit B'', delta	4	0.97
chr7_14536045_14536258	1.13	Obox4-ps2	oocyte specific homeobox 4, pseudogene 2	6085	0.12
chr9_123509919_123510093	1.12	Limd1	LIM domains containing 1	58	0.97
chr19_57197050_57197386	1.12	Ablim1	actin-binding LIM protein 1	173	0.97
chr8_106133706_106133886	1.12	Esrp2	epithelial splicing regulatory protein 2	332	0.78
chr9_64050138_64050305	1.12	Gm25606	predicted gene, 25606	1725	0.26
chr12_103737885_103738489	1.12	Serpina1b	serine (or cysteine) preptidase inhibitor, clade A, member 1B	29	0.96
chr14_118923057_118923208	1.10	Dzip1	DAZ interacting protein 1	35	0.97
chr13_100602341_100602503	1.10	Gm24261	predicted gene, 24261	1937	0.21
chr9_50617423_50617584	1.10	Pih1d2	PIH1 domain containing 2	18	0.5
chr15_102018061_102018244	1.09	Krt18	keratin 18	10028	0.11
chr16_94724040_94724246	1.09	Gm41505	predicted gene, 41505	2249	0.31
chr11_75999819_75999990	1.09	1700016K19Rik	RIKEN cDNA 1700016K19 gene	8	0.98
chr12_76131007_76131193	1.09	Gm7862	predicted gene 7862	21527	0.16
chr9_24503167_24503347	1.08	Dpy19l1	dpy-19-like 1 (C. elegans)	117	0.61
chr18_63708540_63708704	1.08	Wdr7	WD repeat domain 7	63	0.56
chr5_122264387_122264543	1.07	Tctn1	tectonic family member 1	5	0.96
chr4_144873015_144873176	1.07	Dhrs3	dehydrogenase/reductase (SDR family) member 3	19732	0.19
chr3_106001456_106001626	1.07	Gm42722	predicted gene 42722	20	0.5
chr19_41330558_41330729	1.07	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	54453	0.13
chr17_30948483_30948657	1.06	Gm41562	predicted gene, 41562	2677	0.14
chr4_141790772_141790934	1.05	Dnajc16	DnaJ heat shock protein family (Hsp40) member C16	38	0.96
chr10_59503935_59504118	1.05	Mcu	mitochondrial calcium uniporter	45866	0.13
chr17_35979499_35979656	1.04	Prr3	proline-rich polypeptide 3	51	0.74
chr16_97793022_97793199	1.03	Prdm15	PR domain containing 15	4809	0.19
chr18_20974383_20974578	1.03	Rnf125	ring finger protein 125	13008	0.2
chr7_78290316_78290467	1.03	Ntrk3	neurotrophic tyrosine kinase, receptor, type 3	28504	0.19
chr2_168726086_168726249	1.03	Atp9a	ATPase, class II, type 9A	8172	0.2
chr8_72221581_72221755	1.03	Fam32a	family with sequence similarity 32, member A	1904	0.18
chr14_30921562_30921713	1.02	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	1912	0.21
chr7_75910102_75910261	1.02	Klhl25	kelch-like 25	61740	0.12
chr2_93992385_93992562	1.01	Gm27027	predicted gene, 27027	3881	0.17
chr11_72361855_72362025	1.01	Tekt1	tektin 1	67	0.96
chr14_21369173_21369452	1.00	Adk	adenosine kinase	242	0.95
chr3_98198346_98198505	1.00	Gm9771	predicted gene 9771	7323	0.16
chr2_30796583_30796739	1.00	1700001O22Rik	RIKEN cDNA 1700001O22 gene	3	0.96
chr15_67469080_67469242	1.00	1700012I11Rik	RIKEN cDNA 1700012I11 gene	242392	0.02
chr3_57425221_57425383	1.00	Tm4sf4	transmembrane 4 superfamily member 4	12	0.98
chr1_24743279_24743468	1.00	Lmbrd1	LMBR1 domain containing 1	1500	0.46
chr15_76207439_76207714	0.99	Plec	plectin	677	0.46
chr16_23292038_23292189	0.99	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	1643	0.36
chr11_3963349_3963513	0.99	Pes1	pescadillo ribosomal biogenesis factor 1	544	0.61
chr15_64043505_64043715	0.98	Fam49b	family with sequence similarity 49, member B	16720	0.16
chr1_194978169_194978329	0.98	Gm16897	predicted gene, 16897	1289	0.26
chr12_82169230_82169390	0.98	Sipa1l1	signal-induced proliferation-associated 1 like 1	10	0.73
chr5_88929617_88929827	0.98	Slc4a4	solute carrier family 4 (anion exchanger), member 4	4810	0.28
chr13_109880549_109880700	0.98	Pde4d	phosphodiesterase 4D, cAMP specific	22478	0.22
chr11_31941447_31941609	0.97	4930524B15Rik	RIKEN cDNA 4930524B15 gene	24064	0.18
chr5_35609639_35609801	0.96	Acox3	acyl-Coenzyme A oxidase 3, pristanoyl	379	0.82
chr18_46631846_46631997	0.96	Gm3734	predicted gene 3734	1114	0.44
chr5_122799187_122799344	0.96	Anapc5	anaphase-promoting complex subunit 5	465	0.74
chr11_108424915_108425231	0.95	Cep112	centrosomal protein 112	119	0.95
chr1_180237680_180237869	0.95	Psen2	presenilin 2	1448	0.33
chr7_16504987_16505147	0.95	Gm17826	predicted gene, 17826	6335	0.12
chr6_89286854_89287025	0.95	4930512J16Rik	RIKEN cDNA 4930512J16 gene	1214	0.37
chr8_34699073_34699233	0.94	Gm45627	predicted gene 45627	39784	0.15
chr5_134740472_134740630	0.94	Gm30003	predicted gene, 30003	6491	0.15
chr16_23033709_23034045	0.94	Gm8128	predicted gene 8128	155	0.89
chr16_94569602_94569765	0.93	Dyrk1a	dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1a	327	0.89
chr15_97798220_97798573	0.93	Hdac7	histone deacetylase 7	3951	0.16
chr16_4881522_4881711	0.93	Ubald1	UBA-like domain containing 1	1301	0.32
chr13_34265679_34265842	0.93	Gm47086	predicted gene, 47086	53048	0.11
chr11_21549139_21549315	0.92	Mdh1	malate dehydrogenase 1, NAD (soluble)	10502	0.14
chr1_121315889_121316040	0.92	Insig2	insulin induced gene 2	3550	0.2
chr12_111353498_111353831	0.92	Cdc42bpb	CDC42 binding protein kinase beta	23955	0.13
chr4_45483751_45483930	0.92	Shb	src homology 2 domain-containing transforming protein B	1038	0.49
chr18_33552716_33552894	0.92	Gm50392	predicted gene, 50392	23663	0.22
chr8_70610224_70610388	0.92	Gm45546	predicted gene 45546	119	0.9
chr3_89227389_89227544	0.92	Mir92b	microRNA 92b	268	0.5
chr11_83882667_83882848	0.91	Hnf1b	HNF1 homeobox B	29797	0.12
chr9_71062436_71062594	0.91	Gm47268	predicted gene, 47268	64327	0.11
chr15_3281726_3282076	0.90	Selenop	selenoprotein P	9816	0.21
chr7_28442822_28442993	0.90	Gmfg	glia maturation factor, gamma	200	0.86
chr10_33904910_33905080	0.89	Rsph4a	radial spoke head 4 homolog A (Chlamydomonas)	116	0.94
chr11_79039552_79039742	0.89	Gm11201	predicted gene 11201	16050	0.17
chr18_6434248_6434399	0.89	Epc1	enhancer of polycomb homolog 1	7571	0.19

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rfx3_Rfx1_Rfx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:0042126	nitrate metabolic process(GO:0042126)
0.5	1.5	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
0.4	1.1	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.4	1.5	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.3	1.4	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.3	1.4	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.2	0.9	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2	0.7	GO:0031087	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.2	0.6	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.2	2.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.2	1.0	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.2	0.6	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.2	0.8	GO:0090427	activation of meiosis(GO:0090427)
0.2	0.7	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.2	0.5	GO:2000834	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.2	0.7	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.2	0.7	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.2	0.5	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.2	0.2	GO:0035511	oxidative DNA demethylation(GO:0035511)
0.2	1.3	GO:0043312	neutrophil degranulation(GO:0043312)
0.2	1.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.7	GO:1902866	regulation of retina development in camera-type eye(GO:1902866)
0.1	0.6	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1	0.4	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.5	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.1	0.4	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.1	0.5	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.1	0.4	GO:0097503	sialylation(GO:0097503)
0.1	0.6	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.1	0.5	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.1	0.9	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.1	0.8	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.1	0.4	GO:0009080	alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.1	0.6	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.7	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1	1.2	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.1	0.3	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.1	0.3	GO:0033505	floor plate morphogenesis(GO:0033505)
0.1	0.6	GO:0030953	astral microtubule organization(GO:0030953)
0.1	0.3	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1	0.2	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.1	0.3	GO:0021564	vagus nerve development(GO:0021564)
0.1	0.2	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1	2.3	GO:0018345	protein palmitoylation(GO:0018345)
0.1	1.1	GO:0097120	receptor localization to synapse(GO:0097120)
0.1	0.5	GO:0060684	epithelial-mesenchymal cell signaling(GO:0060684)
0.1	0.3	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1	0.3	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.1	0.4	GO:0033483	gas homeostasis(GO:0033483)
0.1	0.6	GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.1	0.8	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.1	0.6	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.1	0.3	GO:0046469	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.1	0.4	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	1.1	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.1	0.4	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.1	0.3	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.1	0.6	GO:0007000	nucleolus organization(GO:0007000)
0.1	0.2	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1	0.3	GO:0002432	granuloma formation(GO:0002432)
0.1	0.9	GO:0003351	epithelial cilium movement(GO:0003351)
0.1	0.3	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1	0.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.2	GO:0052200	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.1	0.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.1	0.4	GO:0061635	regulation of protein complex stability(GO:0061635)
0.1	0.2	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1	0.2	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.1	0.2	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.4	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.1	0.2	GO:0021586	pons maturation(GO:0021586)
0.1	0.2	GO:0051788	response to misfolded protein(GO:0051788)
0.1	0.2	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.1	0.4	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.1	0.4	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.4	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.1	0.2	GO:0033058	directional locomotion(GO:0033058)
0.1	0.7	GO:0033327	Leydig cell differentiation(GO:0033327)
0.1	0.2	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.1	0.4	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.1	0.2	GO:0048682	axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.1	0.3	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.2	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.1	0.6	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.1	0.6	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.1	1.3	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1	0.2	GO:2000507	positive regulation of energy homeostasis(GO:2000507)
0.1	0.2	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1	0.2	GO:2001181	positive regulation of interleukin-10 secretion(GO:2001181)
0.1	0.2	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1	0.4	GO:0044351	macropinocytosis(GO:0044351)
0.1	0.2	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.1	0.1	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.1	0.2	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1	0.3	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.1	0.6	GO:0000103	sulfate assimilation(GO:0000103)
0.1	1.1	GO:0060445	branching involved in salivary gland morphogenesis(GO:0060445)
0.1	0.2	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.1	0.5	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.1	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1	0.6	GO:0045741	positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.1	1.0	GO:0035767	endothelial cell chemotaxis(GO:0035767)
0.1	0.2	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1	0.2	GO:0015819	lysine transport(GO:0015819)
0.1	0.2	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.1	0.2	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	0.2	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.1	0.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.1	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1	0.2	GO:0046909	intermembrane transport(GO:0046909)
0.1	1.5	GO:0048843	negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1	0.1	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	0.4	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.1	0.3	GO:0051189	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1	0.2	GO:0009757	carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.1	0.1	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.2	GO:0090500	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) endocardial cushion to mesenchymal transition(GO:0090500)
0.1	0.5	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.1	0.2	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.1	0.1	GO:0044340	canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.1	0.6	GO:0043248	proteasome assembly(GO:0043248)
0.1	2.1	GO:0006953	acute-phase response(GO:0006953)
0.1	0.2	GO:0003195	tricuspid valve morphogenesis(GO:0003186) tricuspid valve formation(GO:0003195)
0.1	0.1	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.1	0.2	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.1	0.3	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1	0.2	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.1	0.2	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1	0.2	GO:0035995	detection of muscle stretch(GO:0035995)
0.1	0.1	GO:0003104	positive regulation of glomerular filtration(GO:0003104)
0.1	0.2	GO:0090168	Golgi reassembly(GO:0090168)
0.1	0.3	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1	0.2	GO:1902774	late endosome to lysosome transport(GO:1902774)
0.1	0.2	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.1	0.2	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.0	GO:0042023	DNA endoreduplication(GO:0042023)
0.0	0.2	GO:0009115	xanthine catabolic process(GO:0009115)
0.0	0.1	GO:1903726	negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553) negative regulation of phospholipid metabolic process(GO:1903726)
0.0	0.2	GO:0007196	adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0	0.0	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.1	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.0	GO:0090325	regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.1	GO:2000048	negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	1.0	GO:0006301	postreplication repair(GO:0006301)
0.0	0.4	GO:0035269	protein O-linked mannosylation(GO:0035269)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.3	GO:0031937	positive regulation of chromatin silencing(GO:0031937)
0.0	0.1	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	1.5	GO:0035082	axoneme assembly(GO:0035082)
0.0	0.0	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.3	GO:0060159	regulation of dopamine receptor signaling pathway(GO:0060159)
0.0	0.1	GO:0044849	estrous cycle(GO:0044849)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.0	GO:0071611	macrophage colony-stimulating factor production(GO:0036301) granulocyte colony-stimulating factor production(GO:0071611) regulation of granulocyte colony-stimulating factor production(GO:0071655) regulation of macrophage colony-stimulating factor production(GO:1901256)
0.0	0.3	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.6	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.1	GO:0003347	epicardial cell to mesenchymal cell transition(GO:0003347)
0.0	0.2	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.0	GO:1900094	determination of left/right asymmetry in lateral mesoderm(GO:0003140) nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.4	GO:0001675	acrosome assembly(GO:0001675)
0.0	0.2	GO:0031659	positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.2	GO:0072553	terminal button organization(GO:0072553)
0.0	0.1	GO:0071896	protein localization to adherens junction(GO:0071896)
0.0	0.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.2	GO:2001166	regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0	0.1	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0	0.5	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.6	GO:0010575	positive regulation of vascular endothelial growth factor production(GO:0010575)
0.0	0.1	GO:0000479	endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0	0.2	GO:0006685	sphingomyelin catabolic process(GO:0006685)
0.0	0.1	GO:0022009	central nervous system vasculogenesis(GO:0022009)
0.0	0.1	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.6	GO:0007263	nitric oxide mediated signal transduction(GO:0007263)
0.0	0.2	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.0	0.1	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	1.6	GO:0046847	filopodium assembly(GO:0046847)
0.0	0.1	GO:0048012	hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.4	GO:0030517	negative regulation of axon extension(GO:0030517)
0.0	0.5	GO:0001937	negative regulation of endothelial cell proliferation(GO:0001937)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.5	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.4	GO:0006020	inositol metabolic process(GO:0006020)
0.0	1.0	GO:0007032	endosome organization(GO:0007032)
0.0	0.2	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.1	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.5	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.4	GO:0042574	retinal metabolic process(GO:0042574)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.2	GO:1903608	protein localization to cytoplasmic stress granule(GO:1903608)
0.0	0.2	GO:0043562	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.4	GO:0043586	tongue development(GO:0043586)
0.0	0.1	GO:1903121	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.3	GO:0042407	cristae formation(GO:0042407)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.1	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.0	0.1	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.0	GO:0051890	regulation of cardioblast differentiation(GO:0051890)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.2	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.6	GO:0051443	positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0	0.2	GO:0006004	fucose metabolic process(GO:0006004)
0.0	0.3	GO:0008105	asymmetric protein localization(GO:0008105)
0.0	0.2	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.3	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0060648	mammary gland bud morphogenesis(GO:0060648)
0.0	0.1	GO:0034144	negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.0	0.8	GO:0000387	spliceosomal snRNP assembly(GO:0000387)
0.0	0.2	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.4	GO:0072520	seminiferous tubule development(GO:0072520)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	0.0	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	1.2	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0	0.1	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536)
0.0	0.3	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.1	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.2	GO:0032119	sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0	0.0	GO:0043634	polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0	0.1	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.2	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.3	GO:0046697	decidualization(GO:0046697)
0.0	0.2	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0060083	smooth muscle contraction involved in micturition(GO:0060083)
0.0	0.1	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.0	0.1	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.1	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.4	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.1	GO:0001768	establishment of lymphocyte polarity(GO:0001767) establishment of T cell polarity(GO:0001768)
0.0	0.1	GO:1901421	positive regulation of response to alcohol(GO:1901421)
0.0	0.2	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.2	GO:0048875	chemical homeostasis within a tissue(GO:0048875)
0.0	0.1	GO:2000823	regulation of androgen receptor activity(GO:2000823)
0.0	0.2	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
0.0	0.1	GO:0090598	male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0	0.2	GO:0021683	cerebellar granular layer morphogenesis(GO:0021683)
0.0	0.2	GO:0070417	cellular response to cold(GO:0070417)
0.0	1.2	GO:0022900	electron transport chain(GO:0022900)
0.0	1.0	GO:0051155	positive regulation of striated muscle cell differentiation(GO:0051155)
0.0	0.0	GO:2000611	positive regulation of thyroid hormone generation(GO:2000611)
0.0	0.0	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.0	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.1	GO:0003164	His-Purkinje system development(GO:0003164)
0.0	0.0	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0045629	negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0	0.0	GO:0007195	adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0	0.1	GO:2000491	positive regulation of hepatic stellate cell activation(GO:2000491)
0.0	0.3	GO:0051601	exocyst localization(GO:0051601)
0.0	0.2	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.1	GO:0051464	positive regulation of cortisol secretion(GO:0051464)
0.0	0.0	GO:0014826	vein smooth muscle contraction(GO:0014826)
0.0	0.0	GO:0035330	regulation of hippo signaling(GO:0035330)
0.0	0.6	GO:0051220	cytoplasmic sequestering of protein(GO:0051220)
0.0	0.1	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.0	0.0	GO:1901857	positive regulation of cellular respiration(GO:1901857)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.0	GO:0071609	chemokine (C-C motif) ligand 5 production(GO:0071609) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.3	GO:0007064	mitotic sister chromatid cohesion(GO:0007064)
0.0	0.1	GO:0042525	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.1	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.1	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	0.1	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.2	GO:0031987	locomotion involved in locomotory behavior(GO:0031987)
0.0	0.2	GO:0016127	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.2	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.1	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.0	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0	0.1	GO:0021942	radial glia guided migration of Purkinje cell(GO:0021942)
0.0	0.0	GO:0009642	response to light intensity(GO:0009642)
0.0	0.7	GO:1902850	mitotic spindle assembly(GO:0090307) microtubule cytoskeleton organization involved in mitosis(GO:1902850)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.1	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:2000850	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.3	GO:0022617	extracellular matrix disassembly(GO:0022617)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.4	GO:1900087	positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0	0.1	GO:0090166	Golgi disassembly(GO:0090166)
0.0	0.0	GO:0033031	positive regulation of neutrophil apoptotic process(GO:0033031)
0.0	0.4	GO:0046854	phosphatidylinositol phosphorylation(GO:0046854)
0.0	0.0	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.1	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0090273	regulation of somatostatin secretion(GO:0090273)
0.0	0.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.4	GO:0031365	N-terminal protein amino acid modification(GO:0031365)
0.0	0.1	GO:0035988	chondrocyte proliferation(GO:0035988)
0.0	0.1	GO:0060385	axonogenesis involved in innervation(GO:0060385)
0.0	0.0	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.0	GO:0000189	MAPK import into nucleus(GO:0000189)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.2	GO:0032703	negative regulation of interleukin-2 production(GO:0032703)
0.0	0.0	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.0	GO:0035787	cell migration involved in kidney development(GO:0035787)
0.0	0.0	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
0.0	0.0	GO:0006808	regulation of nitrogen utilization(GO:0006808) apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.2	GO:0043306	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.8	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0090244	Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0009071	serine family amino acid catabolic process(GO:0009071)
0.0	0.1	GO:2001198	regulation of dendritic cell differentiation(GO:2001198) negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.2	GO:0019370	leukotriene biosynthetic process(GO:0019370)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.0	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.0	0.1	GO:0046684	response to pyrethroid(GO:0046684)
0.0	0.2	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0060355	positive regulation of cell adhesion molecule production(GO:0060355)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.1	GO:0021940	positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.0	0.1	GO:0001771	immunological synapse formation(GO:0001771)
0.0	0.0	GO:0051917	regulation of fibrinolysis(GO:0051917)
0.0	0.1	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.0	0.2	GO:0006144	purine nucleobase metabolic process(GO:0006144)
0.0	0.1	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:1990000	amyloid fibril formation(GO:1990000)
0.0	0.1	GO:0001732	formation of cytoplasmic translation initiation complex(GO:0001732)
0.0	0.4	GO:0043392	negative regulation of DNA binding(GO:0043392)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:0060421	positive regulation of heart growth(GO:0060421)
0.0	0.0	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.0	GO:0001781	neutrophil apoptotic process(GO:0001781)
0.0	0.1	GO:0019471	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) 4-hydroxyproline metabolic process(GO:0019471)
0.0	0.1	GO:0000291	nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.1	GO:1900264	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.0	GO:1900107	regulation of nodal signaling pathway(GO:1900107)
0.0	0.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.0	GO:0043504	mitochondrial DNA repair(GO:0043504)
0.0	0.0	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.1	GO:0035871	protein K11-linked deubiquitination(GO:0035871)
0.0	0.0	GO:0090027	negative regulation of monocyte chemotaxis(GO:0090027)
0.0	0.0	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0	0.0	GO:2000510	positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0	0.1	GO:0045410	positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.0	0.0	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.2	GO:0002089	lens morphogenesis in camera-type eye(GO:0002089)
0.0	0.0	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.0	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.0	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.0	GO:0043309	regulation of eosinophil degranulation(GO:0043309)
0.0	0.0	GO:0043380	regulation of memory T cell differentiation(GO:0043380)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.4	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.6	GO:0030032	lamellipodium assembly(GO:0030032)
0.0	0.0	GO:0060979	vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0	0.2	GO:2000404	regulation of T cell migration(GO:2000404)
0.0	0.6	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0	0.1	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.0	0.0	GO:0043133	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.0	GO:0002892	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.0	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.4	GO:0007339	binding of sperm to zona pellucida(GO:0007339)
0.0	0.1	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.0	0.2	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.1	GO:0010886	positive regulation of cholesterol storage(GO:0010886)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:0060137	maternal process involved in parturition(GO:0060137) positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.0	GO:0031117	positive regulation of microtubule depolymerization(GO:0031117)
0.0	0.1	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1902035	positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0	0.1	GO:0051351	positive regulation of ligase activity(GO:0051351)
0.0	0.0	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.1	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.0	GO:0018343	protein farnesylation(GO:0018343)
0.0	0.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.0	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.2	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0071545	inositol phosphate catabolic process(GO:0071545)
0.0	0.1	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.0	GO:0014878	response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0	0.3	GO:0007602	phototransduction(GO:0007602)
0.0	0.0	GO:0070458	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:0036015	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.5	GO:0018107	peptidyl-threonine phosphorylation(GO:0018107)
0.0	0.0	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.1	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0032347	regulation of aldosterone biosynthetic process(GO:0032347)
0.0	0.0	GO:0031642	negative regulation of myelination(GO:0031642)
0.0	0.0	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.2	GO:0097028	dendritic cell differentiation(GO:0097028)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.0	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0000338	protein deneddylation(GO:0000338)
0.0	0.0	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.0	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.0	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.0	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0	0.0	GO:0010818	T cell chemotaxis(GO:0010818)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:2001268	negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0	0.0	GO:0072674	multinuclear osteoclast differentiation(GO:0072674)
0.0	0.0	GO:0046598	positive regulation of viral entry into host cell(GO:0046598)
0.0	0.0	GO:0070126	mitochondrial translational termination(GO:0070126)
0.0	0.0	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:2001015	negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0	0.0	GO:0002767	immune response-inhibiting signal transduction(GO:0002765) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0	0.2	GO:0008045	motor neuron axon guidance(GO:0008045)
0.0	0.0	GO:1903748	negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.0	0.1	GO:0016180	snRNA processing(GO:0016180)
0.0	0.1	GO:0043485	endosome to melanosome transport(GO:0035646) cellular pigment accumulation(GO:0043482) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.0	0.1	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.0	GO:0071898	regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:2000781	positive regulation of double-strand break repair(GO:2000781)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.1	GO:0099517	anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0	0.2	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.2	GO:0019835	cytolysis(GO:0019835)
0.0	0.1	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0035934	corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0	0.0	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.0	0.1	GO:0051340	regulation of ligase activity(GO:0051340)
0.0	0.1	GO:0070269	pyroptosis(GO:0070269)
0.0	0.1	GO:0006390	transcription from mitochondrial promoter(GO:0006390)
0.0	0.0	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0002554	serotonin secretion by platelet(GO:0002554)
0.0	0.0	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0071220	response to bacterial lipopeptide(GO:0070339) cellular response to bacterial lipoprotein(GO:0071220) cellular response to bacterial lipopeptide(GO:0071221) response to diacyl bacterial lipopeptide(GO:0071724) cellular response to diacyl bacterial lipopeptide(GO:0071726)
0.0	0.0	GO:0098763	mitotic cell cycle phase(GO:0098763)
0.0	0.1	GO:0007520	myoblast fusion(GO:0007520)
0.0	0.1	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.8	GO:0030915	Smc5-Smc6 complex(GO:0030915)
0.1	0.7	GO:0000235	astral microtubule(GO:0000235)
0.1	0.5	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.1	0.5	GO:1990246	uniplex complex(GO:1990246)
0.1	1.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.1	0.6	GO:0061617	MICOS complex(GO:0061617)
0.1	1.9	GO:0042101	T cell receptor complex(GO:0042101)
0.1	0.5	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1	0.4	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.1	0.5	GO:0005683	U7 snRNP(GO:0005683)
0.1	0.4	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	1.4	GO:0030014	CCR4-NOT complex(GO:0030014)
0.1	1.0	GO:0031332	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.1	0.4	GO:0042825	TAP complex(GO:0042825)
0.1	1.2	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.1	0.4	GO:0070695	FHF complex(GO:0070695)
0.1	0.3	GO:1990357	terminal web(GO:1990357)
0.1	0.2	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1	0.2	GO:0070765	gamma-secretase complex(GO:0070765)
0.1	0.3	GO:1990716	axonemal central apparatus(GO:1990716)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.3	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.2	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.1	0.2	GO:0071942	XPC complex(GO:0071942)
0.1	0.5	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.1	0.4	GO:0031931	TORC1 complex(GO:0031931)
0.1	1.9	GO:0031941	filamentous actin(GO:0031941)
0.1	1.6	GO:0035869	ciliary transition zone(GO:0035869)
0.1	0.7	GO:0005640	nuclear outer membrane(GO:0005640)
0.1	1.1	GO:0060077	inhibitory synapse(GO:0060077)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.7	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1	0.6	GO:0032797	SMN complex(GO:0032797)
0.1	0.3	GO:0002177	manchette(GO:0002177)
0.1	0.3	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.1	0.2	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.2	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.2	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.6	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.8	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0045251	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.1	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.4	GO:0042555	MCM complex(GO:0042555)
0.0	0.3	GO:0097542	ciliary tip(GO:0097542)
0.0	0.2	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.2	GO:0071439	clathrin complex(GO:0071439)
0.0	0.2	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0071953	elastic fiber(GO:0071953)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	1.6	GO:0000932	cytoplasmic mRNA processing body(GO:0000932)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.6	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.3	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.3	GO:0002102	podosome(GO:0002102)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0045240	dihydrolipoyl dehydrogenase complex(GO:0045240)
0.0	0.1	GO:0033503	HULC complex(GO:0033503)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.6	GO:0045120	pronucleus(GO:0045120)
0.0	0.3	GO:0000815	ESCRT III complex(GO:0000815)
0.0	1.3	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0045261	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.3	GO:0031527	filopodium membrane(GO:0031527)
0.0	3.0	GO:0001726	ruffle(GO:0001726)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.3	GO:0030140	trans-Golgi network transport vesicle(GO:0030140)
0.0	0.1	GO:0005663	DNA replication factor C complex(GO:0005663)
0.0	0.6	GO:0030686	90S preribosome(GO:0030686)
0.0	0.2	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.3	GO:0005797	Golgi medial cisterna(GO:0005797)
0.0	0.2	GO:0005869	dynactin complex(GO:0005869)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.2	GO:0090665	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.2	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.5	GO:0016235	aggresome(GO:0016235)
0.0	0.1	GO:0034991	nuclear meiotic cohesin complex(GO:0034991)
0.0	1.8	GO:0016607	nuclear speck(GO:0016607)
0.0	0.1	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.3	GO:0005614	interstitial matrix(GO:0005614)
0.0	0.3	GO:0000145	exocyst(GO:0000145)
0.0	0.9	GO:0000502	proteasome complex(GO:0000502)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	3.4	GO:0045211	postsynaptic membrane(GO:0045211)
0.0	0.1	GO:0008275	gamma-tubulin small complex(GO:0008275)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0030677	nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0072588	box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0005927	muscle tendon junction(GO:0005927)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.1	GO:0033178	proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0	0.1	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.9	GO:0031463	Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0	0.0	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.0	GO:0030478	actin cap(GO:0030478)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.0	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.0	0.0	GO:0005818	aster(GO:0005818)
0.0	0.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	1.4	GO:0001669	acrosomal vesicle(GO:0001669)
0.0	0.1	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.0	0.1	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.0	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.0	0.8	GO:0005901	caveola(GO:0005901)
0.0	1.1	GO:0000784	nuclear chromosome, telomeric region(GO:0000784)
0.0	0.1	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.1	GO:0005861	troponin complex(GO:0005861)
0.0	0.1	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.0	0.3	GO:0051233	spindle midzone(GO:0051233)
0.0	0.2	GO:0030057	desmosome(GO:0030057)
0.0	0.2	GO:0032590	dendrite membrane(GO:0032590)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	1.2	GO:0005802	trans-Golgi network(GO:0005802)
0.0	0.0	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.7	GO:0022625	cytosolic large ribosomal subunit(GO:0022625)
0.0	0.2	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.4	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.8	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.1	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.0	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0000800	lateral element(GO:0000800)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.6	1.7	GO:1901612	cardiolipin binding(GO:1901612)
0.4	1.2	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.4	1.5	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.3	1.7	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.3	1.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.2	1.3	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.2	0.6	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	0.5	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.2	0.2	GO:0009041	uridylate kinase activity(GO:0009041)
0.2	0.2	GO:0035514	DNA demethylase activity(GO:0035514)
0.2	0.5	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1	0.4	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.4	GO:0071209	U7 snRNA binding(GO:0071209)
0.1	1.1	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1	0.4	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.1	0.4	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1	0.3	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.1	0.8	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.1	1.2	GO:0048156	tau protein binding(GO:0048156)
0.1	0.1	GO:0015440	peptide-transporting ATPase activity(GO:0015440)
0.1	1.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.1	1.2	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1	2.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1	0.4	GO:0051434	BH3 domain binding(GO:0051434)
0.1	0.3	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.1	0.4	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.1	0.3	GO:0008142	oxysterol binding(GO:0008142)
0.1	0.5	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.3	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.1	0.4	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.7	GO:0019206	nucleoside kinase activity(GO:0019206)
0.1	0.5	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1	0.4	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1	0.3	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1	1.4	GO:0030215	semaphorin receptor binding(GO:0030215)
0.1	0.2	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.1	0.3	GO:0016361	activin receptor activity, type I(GO:0016361)
0.1	0.5	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.1	0.3	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.1	0.6	GO:0034582	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.1	0.2	GO:0008506	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	2.0	GO:0005154	epidermal growth factor receptor binding(GO:0005154)
0.1	0.2	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.1	0.2	GO:0004582	dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1	0.3	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.1	0.2	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.3	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.1	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.1	1.1	GO:0017025	TBP-class protein binding(GO:0017025)
0.1	0.4	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.1	0.1	GO:0004127	cytidylate kinase activity(GO:0004127)
0.1	0.3	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1	0.3	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	0.4	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.6	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0001642	group III metabotropic glutamate receptor activity(GO:0001642)
0.0	0.2	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.2	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	1.0	GO:0071889	14-3-3 protein binding(GO:0071889)
0.0	0.0	GO:0000701	purine-specific mismatch base pair DNA N-glycosylase activity(GO:0000701)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.2	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.2	GO:0043842	Kdo transferase activity(GO:0043842)
0.0	0.2	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.6	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.3	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.4	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.4	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.0	0.2	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.3	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
0.0	0.2	GO:0050733	RS domain binding(GO:0050733)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.4	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.5	GO:0008574	ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0	0.5	GO:0048018	receptor agonist activity(GO:0048018)
0.0	0.2	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.5	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.6	GO:0016671	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.0	0.8	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.2	GO:0019911	structural constituent of myelin sheath(GO:0019911)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	1.0	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	1.3	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.1	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.5	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.5	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0008381	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0	0.4	GO:0031005	filamin binding(GO:0031005)
0.0	0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.6	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	1.0	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.4	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.5	GO:0009931	calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.2	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.5	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.4	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.1	GO:0034604	pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.9	GO:0052693	N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693)
0.0	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.3	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.5	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.0	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	1.4	GO:0005089	Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0	0.6	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.8	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.3	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.5	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.2	GO:0033170	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.5	GO:0008373	sialyltransferase activity(GO:0008373)
0.0	0.2	GO:0046933	proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0	0.2	GO:0098632	protein binding involved in cell-cell adhesion(GO:0098632)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.7	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.7	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.0	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.1	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.1	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0070051	fibrinogen binding(GO:0070051)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0031014	troponin T binding(GO:0031014)
0.0	0.7	GO:0005109	frizzled binding(GO:0005109)
0.0	0.3	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.0	0.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.1	GO:1904680	peptide transmembrane transporter activity(GO:1904680)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0016728	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0	0.0	GO:0010857	calcium-dependent protein kinase activity(GO:0010857)
0.0	0.2	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.1	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.4	GO:0019825	oxygen binding(GO:0019825)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.7	GO:0008009	chemokine activity(GO:0008009)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.3	GO:0097506	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.2	GO:0032296	ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.1	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.2	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.4	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.1	GO:0004711	ribosomal protein S6 kinase activity(GO:0004711)
0.0	0.0	GO:0004854	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0	0.1	GO:0017089	glycolipid transporter activity(GO:0017089)
0.0	0.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.2	GO:0046961	ATPase activity, coupled to transmembrane movement of ions, rotational mechanism(GO:0044769) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.9	GO:0048306	calcium-dependent protein binding(GO:0048306)
0.0	0.1	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.1	GO:0008379	thioredoxin peroxidase activity(GO:0008379)
0.0	0.1	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0016783	sulfurtransferase activity(GO:0016783)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.5	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.1	GO:0031685	adenosine receptor binding(GO:0031685)
0.0	0.2	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.8	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.7	GO:0003684	damaged DNA binding(GO:0003684)
0.0	0.0	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0	0.0	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.0	GO:0050693	LBD domain binding(GO:0050693)
0.0	1.2	GO:0004702	receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.0	GO:0047623	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.1	GO:0017099	very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0	0.5	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0097001	ceramide binding(GO:0097001)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.1	GO:0003933	GTP cyclohydrolase activity(GO:0003933)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.0	GO:0008900	hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0	0.5	GO:0097110	scaffold protein binding(GO:0097110)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.4	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.0	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.0	GO:0043199	sulfate binding(GO:0043199)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.0	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0004931	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0034450	ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.4	GO:0005164	tumor necrosis factor receptor binding(GO:0005164)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.8	GO:0003697	single-stranded DNA binding(GO:0003697)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.0	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.2	GO:0050681	androgen receptor binding(GO:0050681)
0.0	0.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.2	GO:0001871	pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0	0.4	GO:0031593	polyubiquitin binding(GO:0031593)
0.0	0.0	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.0	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.0	0.0	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0005223	intracellular cGMP activated cation channel activity(GO:0005223)
0.0	0.1	GO:0008273	calcium, potassium:sodium antiporter activity(GO:0008273)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.2	GO:0005385	zinc ion transmembrane transporter activity(GO:0005385)
0.0	0.2	GO:0043274	phospholipase binding(GO:0043274)
0.0	0.0	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.0	0.0	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.0	GO:0032557	pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.0	GO:0071253	connexin binding(GO:0071253)
0.0	1.1	GO:0003729	mRNA binding(GO:0003729)
0.0	0.1	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.0	GO:0051380	norepinephrine binding(GO:0051380)
0.0	0.1	GO:0016624	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0	0.0	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0005534	galactose binding(GO:0005534)
0.0	0.2	GO:0000175	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0008332	low voltage-gated calcium channel activity(GO:0008332)
0.0	0.0	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.0	GO:0043394	proteoglycan binding(GO:0043394)
0.0	0.3	GO:0004812	aminoacyl-tRNA ligase activity(GO:0004812)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.2	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
1.3	PID NETRIN PATHWAY	Netrin-mediated signaling events
0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.7	PID IGF1 PATHWAY	IGF1 pathway
2.1	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.4	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.7	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.6	PID ARF 3PATHWAY	Arf1 pathway
0.7	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.7	PID ARF6 PATHWAY	Arf6 signaling events
0.3	PID ALK1 PATHWAY	ALK1 signaling events
0.4	PID IL3 PATHWAY	IL3-mediated signaling events
0.4	PID ERBB2 ERBB3 PATHWAY	ErbB2/ErbB3 signaling events
0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.0	PID GMCSF PATHWAY	GMCSF-mediated signaling events
0.6	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.4	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.7	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.6	PID ATR PATHWAY	ATR signaling pathway
0.6	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.8	PID MYC REPRESS PATHWAY	Validated targets of C-MYC transcriptional repression
0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.5	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.1	PID FOXO PATHWAY	FoxO family signaling
0.1	PID LYMPH ANGIOGENESIS PATHWAY	VEGFR3 signaling in lymphatic endothelium
0.2	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.2	PID PI3KCI PATHWAY	Class I PI3K signaling events
0.0	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.2	PID PTP1B PATHWAY	Signaling events mediated by PTP1B
0.1	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	PID ENDOTHELIN PATHWAY	Endothelins
0.3	PID BMP PATHWAY	BMP receptor signaling
0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.1	PID IL1 PATHWAY	IL1-mediated signaling events
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.1	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	PID REELIN PATHWAY	Reelin signaling pathway
1.4	NABA ECM AFFILIATED	Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.1	1.2	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.1	1.0	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.1	1.0	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	1.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.1	0.9	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1	0.1	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.1	0.5	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.1	0.5	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.1	1.0	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.1	1.2	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.1	0.5	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	1.7	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.8	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.5	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.0	0.2	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY KSRP	Genes involved in Destabilization of mRNA by KSRP
0.0	0.4	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.1	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0	0.9	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.6	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	1.2	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.6	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.7	REACTOME MITOCHONDRIAL TRNA AMINOACYLATION	Genes involved in Mitochondrial tRNA aminoacylation
0.0	0.7	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.4	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.4	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.3	REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS	Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0	0.8	REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA	Genes involved in Circadian Repression of Expression by REV-ERBA
0.0	0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	0.5	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.5	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.3	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.5	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.2	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.0	0.5	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.0	0.2	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	1.1	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.3	REACTOME G ALPHA I SIGNALLING EVENTS	Genes involved in G alpha (i) signalling events
0.0	0.3	REACTOME FGFR1 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR1 ligand binding and activation
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.6	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	0.0	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.3	REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS	Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0	0.9	REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS	Genes involved in Golgi Associated Vesicle Biogenesis
0.0	0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	0.2	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	0.3	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.3	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.3	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.4	REACTOME CHONDROITIN SULFATE BIOSYNTHESIS	Genes involved in Chondroitin sulfate biosynthesis
0.0	0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0	0.1	REACTOME G ALPHA Q SIGNALLING EVENTS	Genes involved in G alpha (q) signalling events
0.0	0.3	REACTOME MRNA SPLICING MINOR PATHWAY	Genes involved in mRNA Splicing - Minor Pathway
0.0	0.2	REACTOME SIGNALING BY FGFR1 MUTANTS	Genes involved in Signaling by FGFR1 mutants
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.1	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.4	REACTOME MEIOTIC SYNAPSIS	Genes involved in Meiotic Synapsis
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.6	REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S	Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME SIGNALING BY ROBO RECEPTOR	Genes involved in Signaling by Robo receptor
0.0	0.6	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.1	REACTOME OPSINS	Genes involved in Opsins
0.0	0.4	REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS	Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0	0.1	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.0	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.0	1.2	REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION	Genes involved in Factors involved in megakaryocyte development and platelet production
0.0	0.2	REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS	Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0	0.0	REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS	Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0	0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.2	REACTOME INFLAMMASOMES	Genes involved in Inflammasomes
0.0	0.4	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.0	0.5	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.2	REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER	Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0	0.3	REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS	Genes involved in Activation of ATR in response to replication stress
0.0	0.1	REACTOME RNA POL III CHAIN ELONGATION	Genes involved in RNA Polymerase III Chain Elongation
0.0	0.1	REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX	Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0	0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.5	REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C	Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0	0.0	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.3	REACTOME MHC CLASS II ANTIGEN PRESENTATION	Genes involved in MHC class II antigen presentation
0.0	0.1	REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.0	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels

Results for Rfx3_Rfx1_Rfx4

Z-value: 4.74

Motif logo

Transcription factors associated with Rfx3_Rfx1_Rfx4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Rfx3_Rfx1_Rfx4 motif across conditions

Conditions sorted by the z-value of the Rfx3_Rfx1_Rfx4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rfx3_Rfx1_Rfx4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: