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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Rreb1

Z-value: 2.10

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Transcription factors associated with Rreb1

Gene Symbol	Gene ID	Gene Info
Rreb1 Ensembl NCBI MGI UniProt	ENSMUSG00000039087.10	ras responsive element binding protein 1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr13_37779207_37779426	Rreb1	916	0.514807	0.92	1.0e-02	Click!
chr13_37912095_37912275	Rreb1	23314	0.185962	-0.88	2.2e-02	Click!
chr13_37845722_37845913	Rreb1	12117	0.192690	-0.86	3.0e-02	Click!
chr13_37866047_37866235	Rreb1	8207	0.215890	0.83	4.0e-02	Click!
chr13_37827559_37827750	Rreb1	261	0.917719	0.83	4.3e-02	Click!

Activity of the Rreb1 motif across conditions

Conditions sorted by the z-value of the Rreb1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr13_93630535_93630727	1.64	Gm15622	predicted gene 15622	5249	0.17
chr1_39192284_39192607	1.16	Npas2	neuronal PAS domain protein 2	1286	0.45
chr17_31872001_31872152	0.93	Sik1	salt inducible kinase 1	16272	0.13
chr10_59786684_59786837	0.89	Gm17059	predicted gene 17059	13494	0.14
chr1_72827270_72827421	0.88	Igfbp2	insulin-like growth factor binding protein 2	2023	0.37
chr19_46133855_46134398	0.88	Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	2229	0.19
chr4_141276769_141276920	0.78	Gm13056	predicted gene 13056	1595	0.24
chr8_126707171_126707322	0.74	Gm45805	predicted gene 45805	51088	0.15
chr13_60479839_60480430	0.72	Gm48500	predicted gene, 48500	1164	0.45
chr10_85186626_85186777	0.69	Cry1	cryptochrome 1 (photolyase-like)	1637	0.39
chr5_150227882_150228033	0.68	Gm36378	predicted gene, 36378	15906	0.19
chr3_85859423_85859574	0.68	Gm37240	predicted gene, 37240	27870	0.1
chr9_121906088_121906239	0.65	Ackr2	atypical chemokine receptor 2	1	0.95
chrX_87238307_87238458	0.62	Gm8855	predicted gene 8855	435487	0.01
chr2_31492850_31493284	0.62	Ass1	argininosuccinate synthetase 1	4705	0.21
chr6_91707022_91707254	0.62	Gm45828	predicted gene 45828	2268	0.2
chr11_33931902_33932233	0.61	Kcnmb1	potassium large conductance calcium-activated channel, subfamily M, beta member 1	30946	0.19
chr17_84896257_84896408	0.57	Gm49982	predicted gene, 49982	6237	0.19
chr4_62780734_62780897	0.56	Gm24117	predicted gene, 24117	31613	0.15
chr16_37867529_37867680	0.56	Lrrc58	leucine rich repeat containing 58	785	0.54
chr12_21141056_21141213	0.55	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	29180	0.17
chr4_148712874_148713025	0.54	Gm13203	predicted gene 13203	754	0.66
chr4_137874478_137874749	0.53	Gm13012	predicted gene 13012	8799	0.2
chr6_125486009_125486160	0.53	Gm28809	predicted gene 28809	4140	0.17
chr8_3393831_3393982	0.52	Arhgef18	rho/rac guanine nucleotide exchange factor (GEF) 18	833	0.6
chr1_120118168_120118368	0.52	Dbi	diazepam binding inhibitor	1870	0.3
chr12_108837829_108837980	0.52	Slc25a47	solute carrier family 25, member 47	840	0.31
chr12_59194921_59195102	0.52	Fbxo33	F-box protein 33	9425	0.15
chr7_31053117_31053317	0.51	Fxyd1	FXYD domain-containing ion transport regulator 1	95	0.91
chr2_60863337_60863488	0.51	Rbms1	RNA binding motif, single stranded interacting protein 1	18026	0.26
chr3_97655610_97655761	0.51	Prkab2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	2508	0.2
chr6_23392505_23392811	0.50	Cadps2	Ca2+-dependent activator protein for secretion 2	36739	0.19
chr2_157571407_157571591	0.50	Blcap	bladder cancer associated protein	225	0.89
chr15_88820456_88820732	0.50	Creld2	cysteine-rich with EGF-like domains 2	948	0.39
chr8_123812047_123812213	0.49	Rab4a	RAB4A, member RAS oncogene family	6062	0.1
chr19_30171407_30171581	0.49	Gldc	glycine decarboxylase	3935	0.23
chr17_34955918_34956069	0.49	Gm8696	predicted gene 8696	1281	0.14
chr15_85716911_85717062	0.49	Mirlet7b	microRNA let7b	9667	0.13
chr9_121912346_121912498	0.48	Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	3883	0.1
chr11_101668758_101669043	0.47	Arl4d	ADP-ribosylation factor-like 4D	3359	0.12
chr13_45963217_45963398	0.47	Atxn1	ataxin 1	1650	0.33
chr1_191946290_191946441	0.46	Rd3	retinal degeneration 3	31005	0.1
chr15_103364813_103364984	0.46	Itga5	integrin alpha 5 (fibronectin receptor alpha)	1850	0.21
chr13_60607775_60607969	0.46	Dapk1	death associated protein kinase 1	5640	0.18
chr7_63896677_63896828	0.46	Gm27252	predicted gene 27252	219	0.91
chr2_103850440_103850628	0.46	Gm13879	predicted gene 13879	6878	0.09
chr14_73630476_73630939	0.45	Gm21750	predicted gene, 21750	30518	0.15
chr10_43742623_43743061	0.44	Gm40634	predicted gene, 40634	245	0.89
chr9_63550824_63550989	0.44	Gm16759	predicted gene, 16759	19554	0.18
chr3_89271513_89271664	0.42	Slc50a1	solute carrier family 50 (sugar transporter), member 1	1018	0.25
chr7_112300238_112300389	0.42	Mical2	microtubule associated monooxygenase, calponin and LIM domain containing 2	15716	0.27
chr3_84258598_84259173	0.42	Trim2	tripartite motif-containing 2	484	0.86
chr2_60383459_60383659	0.42	Ly75	lymphocyte antigen 75	256	0.91
chr10_94159643_94159802	0.42	Nr2c1	nuclear receptor subfamily 2, group C, member 1	3436	0.18
chr10_95780270_95780625	0.42	4732465J04Rik	RIKEN cDNA 4732465J04 gene	1530	0.29
chr16_38246497_38246731	0.42	Gsk3b	glycogen synthase kinase 3 beta	38576	0.11
chr3_51255928_51256079	0.42	Elf2	E74-like factor 2	4238	0.15
chr4_135326152_135326330	0.41	Srrm1	serine/arginine repetitive matrix 1	982	0.41
chr4_144908630_144908793	0.41	Dhrs3	dehydrogenase/reductase (SDR family) member 3	10168	0.21
chr2_163750130_163750300	0.41	Ada	adenosine deaminase	24	0.98
chr10_99222701_99222877	0.41	Gm34574	predicted gene, 34574	277	0.85
chr3_52258108_52258303	0.40	Foxo1	forkhead box O1	10131	0.12
chr11_102142277_102142428	0.40	Nags	N-acetylglutamate synthase	3161	0.11
chr15_7070249_7070660	0.40	Lifr	LIF receptor alpha	20160	0.25
chr14_30891050_30891367	0.40	Itih4	inter alpha-trypsin inhibitor, heavy chain 4	4687	0.13
chr19_46714530_46714681	0.40	As3mt	arsenic (+3 oxidation state) methyltransferase	2633	0.2
chr11_4115460_4115726	0.40	Sec14l2	SEC14-like lipid binding 2	3103	0.12
chr17_12682270_12682463	0.39	Slc22a1	solute carrier family 22 (organic cation transporter), member 1	6537	0.17
chr12_76554293_76554484	0.39	AI463170	expressed sequence AI463170	6445	0.14
chr1_131275281_131275570	0.39	Ikbke	inhibitor of kappaB kinase epsilon	1288	0.32
chr5_125313647_125313811	0.39	Scarb1	scavenger receptor class B, member 1	2903	0.2
chr18_54969498_54969696	0.39	Zfp608	zinc finger protein 608	12840	0.2
chr8_44972192_44972436	0.39	Fat1	FAT atypical cadherin 1	22100	0.17
chr5_122520868_122521019	0.38	Gm22965	predicted gene, 22965	14154	0.09
chr10_42764114_42764349	0.38	Sec63	SEC63-like (S. cerevisiae)	2425	0.25
chr2_31505484_31505674	0.38	Ass1	argininosuccinate synthetase 1	4853	0.2
chr12_76289294_76289480	0.38	Mthfd1	methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase	3678	0.14
chr17_34398487_34398638	0.38	BC051142	cDNA sequence BC051142	258	0.59
chr9_78192592_78192962	0.38	Gsta4	glutathione S-transferase, alpha 4	830	0.46
chr8_123757273_123757470	0.38	4732419C18Rik	RIKEN cDNA 4732419C18 gene	2645	0.11
chr4_133184820_133185010	0.37	Wasf2	WAS protein family, member 2	4103	0.15
chr6_122595445_122595623	0.37	Apobec1	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1	4593	0.12
chr13_93633844_93634026	0.37	Bhmt	betaine-homocysteine methyltransferase	3631	0.19
chr12_54967535_54967800	0.37	Gm27014	predicted gene, 27014	4603	0.15
chr2_103867069_103867263	0.37	Gm13876	predicted gene 13876	21158	0.08
chr3_66035020_66035198	0.37	Gm6546	predicted gene 6546	3590	0.17
chr11_109651940_109652143	0.37	Prkar1a	protein kinase, cAMP dependent regulatory, type I, alpha	1120	0.46
chr17_80325457_80325860	0.37	Arhgef33	Rho guanine nucleotide exchange factor (GEF) 33	18233	0.15
chr9_30897343_30897518	0.37	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	12227	0.22
chr12_8507138_8507301	0.36	5033421B08Rik	RIKEN cDNA 5033421B08 gene	3982	0.18
chr10_84907603_84907783	0.36	Ric8b	RIC8 guanine nucleotide exchange factor B	9923	0.24
chr18_38856344_38856590	0.36	Fgf1	fibroblast growth factor 1	2281	0.33
chr7_28595870_28596035	0.36	Pak4	p21 (RAC1) activated kinase 4	2134	0.15
chr10_18395038_18395462	0.36	Nhsl1	NHS-like 1	4928	0.26
chr19_3895426_3895581	0.36	Tcirg1	T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3	1727	0.17
chr2_170405048_170405199	0.36	Bcas1os1	breast carcinoma amplified sequence 1, opposite strand 1	58	0.96
chr5_124425906_124426318	0.35	Sbno1	strawberry notch 1	111	0.73
chr5_150227352_150227751	0.35	Gm36378	predicted gene, 36378	16312	0.19
chr5_120495968_120496124	0.35	Plbd2	phospholipase B domain containing 2	7555	0.11
chr6_72624193_72624362	0.35	Gm15401	predicted gene 15401	5011	0.09
chr14_63942095_63942273	0.35	Sox7	SRY (sex determining region Y)-box 7	1489	0.38
chr3_121446410_121446561	0.35	Cnn3	calponin 3, acidic	3281	0.18
chr16_21818058_21818209	0.35	Map3k13	mitogen-activated protein kinase kinase kinase 13	7809	0.12
chr9_14174315_14174466	0.35	Gm47564	predicted gene, 47564	29693	0.15
chr1_156073065_156073216	0.35	Tor1aip2	torsin A interacting protein 2	9927	0.17
chr14_29998857_29999427	0.35	Il17rb	interleukin 17 receptor B	683	0.54
chr11_43643345_43643496	0.35	Gm12149	predicted gene 12149	27091	0.12
chr6_145343654_145343918	0.35	Gm23498	predicted gene, 23498	23072	0.11
chr17_34722831_34722982	0.35	Cyp21a2-ps	cytochrome P450, family 21, subfamily a, polypeptide 2 pseudogene	654	0.44
chr18_20990195_20990346	0.35	Rnf138	ring finger protein 138	11071	0.2
chrX_13275719_13275870	0.35	Ddx3x	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked	5176	0.14
chr5_125323526_125323720	0.35	Gm42633	predicted gene 42633	2179	0.22
chr8_46479835_46479986	0.35	Gm45244	predicted gene 45244	6320	0.16
chr4_136138924_136139083	0.35	Gm26001	predicted gene, 26001	1507	0.3
chr11_75279612_75279763	0.35	Gm47300	predicted gene, 47300	38921	0.1
chr1_72810299_72810480	0.34	Igfbp2	insulin-like growth factor binding protein 2	14114	0.21
chr1_105905887_105906083	0.34	Gm37779	predicted gene, 37779	14973	0.17
chr11_120009704_120009855	0.34	Aatk	apoptosis-associated tyrosine kinase	2629	0.15
chr4_123093071_123093222	0.34	Gm12923	predicted gene 12923	882	0.46
chr17_47593664_47594464	0.34	Ccnd3	cyclin D3	249	0.86
chr9_57638948_57639112	0.34	Csk	c-src tyrosine kinase	4963	0.12
chr2_127071034_127071236	0.34	Blvra	biliverdin reductase A	442	0.79
chr5_8056810_8056986	0.34	Sri	sorcin	290	0.85
chr15_59775397_59775598	0.34	Gm19510	predicted gene, 19510	19462	0.24
chr8_12800203_12800354	0.34	Atp11a	ATPase, class VI, type 11A	11138	0.16
chr8_46750315_46750466	0.33	Irf2	interferon regulatory factor 2	10124	0.14
chr13_113022309_113022460	0.33	Cdc20b	cell division cycle 20B	12727	0.08
chr12_110867720_110867879	0.33	Mpc1-ps	mitochondrial pyruvate carrier 1, pseudogene	8905	0.09
chr14_40930703_40931117	0.33	Tspan14	tetraspanin 14	3406	0.26
chr6_99175134_99175460	0.33	Foxp1	forkhead box P1	12279	0.28
chr1_67039034_67039385	0.33	Lancl1	LanC (bacterial lantibiotic synthetase component C)-like 1	337	0.9
chr5_141381660_141381822	0.33	Gm16035	predicted gene 16035	815	0.63
chr11_116165413_116165564	0.33	Fbf1	Fas (TNFRSF6) binding factor 1	395	0.67
chr11_46578775_46579093	0.33	BC053393	cDNA sequence BC053393	7398	0.13
chrX_36644878_36645044	0.33	Akap17b	A kinase (PRKA) anchor protein 17B	135	0.96
chr7_35802959_35803128	0.33	Zfp507	zinc finger protein 507	40	0.88
chr2_30418585_30418853	0.33	Ptpa	protein phosphatase 2 protein activator	2417	0.15
chr12_8433741_8433892	0.33	Gm48076	predicted gene, 48076	21102	0.15
chr11_120521031_120521212	0.32	Gm11789	predicted gene 11789	9433	0.06
chr4_107020194_107020543	0.32	Gm12786	predicted gene 12786	2131	0.26
chr18_65223520_65223956	0.32	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	15854	0.15
chr8_57488604_57488764	0.32	2500002B13Rik	RIKEN cDNA 2500002B13 gene	630	0.45
chr11_53359050_53359204	0.32	Aff4	AF4/FMR2 family, member 4	8294	0.11
chr10_81600790_81601143	0.32	Tle6	transducin-like enhancer of split 6	66	0.93
chr15_88859255_88859406	0.32	Pim3	proviral integration site 3	2856	0.19
chr14_70154015_70154175	0.32	Ccar2	cell cycle activator and apoptosis regulator 2	284	0.85
chr18_46336206_46336490	0.32	4930415P13Rik	RIKEN cDNA 4930415P13 gene	4081	0.17
chr13_93636362_93636873	0.32	Bhmt	betaine-homocysteine methyltransferase	949	0.5
chr7_118739850_118740027	0.32	Vps35l	VPS35 endosomal protein sorting factor like	288	0.8
chr15_76558868_76559133	0.32	Adck5	aarF domain containing kinase 5	17358	0.06
chr7_3230802_3230999	0.32	Mir295	microRNA 295	10127	0.06
chr1_180161827_180161978	0.32	Cdc42bpa	CDC42 binding protein kinase alpha	895	0.53
chr6_117167479_117167672	0.31	Cxcl12	chemokine (C-X-C motif) ligand 12	960	0.54
chr1_39949768_39950072	0.31	Map4k4	mitogen-activated protein kinase kinase kinase kinase 4	14235	0.22
chr17_34605267_34605661	0.31	Agpat1	1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)	397	0.55
chr6_48595035_48595341	0.31	Repin1	replication initiator 1	869	0.27
chr18_20666842_20666993	0.31	Ttr	transthyretin	1637	0.28
chr11_79224332_79224483	0.31	Gm11200	predicted gene 11200	11611	0.17
chr6_125309060_125309481	0.31	Ltbr	lymphotoxin B receptor	295	0.81
chr1_67140040_67140230	0.31	Cps1	carbamoyl-phosphate synthetase 1	17109	0.23
chr17_34836259_34836412	0.31	Stk19	serine/threonine kinase 19	130	0.8
chrX_7656942_7657153	0.30	Gm14703	predicted gene 14703	211	0.46
chr11_5486133_5486285	0.30	Gm11962	predicted gene 11962	9237	0.14
chr19_46976168_46976319	0.30	Nt5c2	5'-nucleotidase, cytosolic II	6675	0.17
chr9_62361596_62361747	0.30	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	5267	0.23
chr18_46603768_46603972	0.30	Eif1a	eukaryotic translation initiation factor 1A	5856	0.15
chr3_156999583_156999772	0.30	Gm43527	predicted gene 43527	740	0.74
chr19_37702993_37703212	0.30	Cyp26a1	cytochrome P450, family 26, subfamily a, polypeptide 1	5017	0.2
chr7_98413497_98413672	0.30	Gm44507	predicted gene 44507	2040	0.24
chr9_48724021_48724519	0.30	Zbtb16	zinc finger and BTB domain containing 16	111675	0.06
chr12_111819707_111819858	0.30	Zfyve21	zinc finger, FYVE domain containing 21	3526	0.14
chr2_31490719_31491007	0.30	Ass1	argininosuccinate synthetase 1	6909	0.19
chr16_10541317_10541611	0.29	Dexi	dexamethasone-induced transcript	1590	0.35
chr6_51362990_51363148	0.29	Gm6559	predicted gene 6559	16641	0.18
chr4_147847988_147848325	0.29	Zfp933	zinc finger protein 933	210	0.88
chr17_31852879_31853048	0.29	Sik1	salt inducible kinase 1	1388	0.38
chr10_96924578_96924746	0.29	Gm33981	predicted gene, 33981	34209	0.17
chr5_135029120_135029476	0.29	Stx1a	syntaxin 1A (brain)	5738	0.08
chr2_31451697_31451848	0.29	Hmcn2	hemicentin 2	2936	0.26
chr8_120409781_120409965	0.29	Gm22715	predicted gene, 22715	33676	0.16
chr3_84813766_84813917	0.29	Fbxw7	F-box and WD-40 domain protein 7	1427	0.53
chr9_65243868_65244187	0.29	Cilp	cartilage intermediate layer protein, nucleotide pyrophosphohydrolase	21153	0.1
chr4_63557379_63557840	0.29	Tmem268	transmembrane protein 268	1172	0.35
chr15_80225601_80225752	0.29	4930588D02Rik	RIKEN cDNA 4930588D02 gene	2738	0.15
chr1_191956791_191956971	0.29	Rd3	retinal degeneration 3	20489	0.11
chr1_184871816_184871971	0.29	C130074G19Rik	RIKEN cDNA C130074G19 gene	11325	0.16
chr6_72787755_72787940	0.29	Tcf7l1	transcription factor 7 like 1 (T cell specific, HMG box)	751	0.63
chr18_4844934_4845219	0.29	Gm10556	predicted gene 10556	32590	0.2
chr10_111335589_111335748	0.28	Gm40761	predicted gene, 40761	1456	0.43
chr8_126660866_126661445	0.28	Irf2bp2	interferon regulatory factor 2 binding protein 2	67169	0.11
chr17_45595822_45596123	0.28	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	15	0.95
chr14_16248790_16249022	0.28	Oxsm	3-oxoacyl-ACP synthase, mitochondrial	268	0.58
chr10_62413042_62413209	0.28	Hkdc1	hexokinase domain containing 1	1321	0.36
chr7_100011175_100011513	0.28	Chrdl2	chordin-like 2	1430	0.34
chr1_39025074_39025225	0.28	Pdcl3	phosducin-like 3	29989	0.13
chr8_44970573_44970724	0.28	Fat1	FAT atypical cadherin 1	20434	0.18
chr4_123663878_123664029	0.28	Macf1	microtubule-actin crosslinking factor 1	799	0.5
chr12_111373260_111373430	0.28	Cdc42bpb	CDC42 binding protein kinase beta	4274	0.17
chr17_31637083_31637756	0.28	Cbs	cystathionine beta-synthase	181	0.89
chr18_35598169_35598395	0.28	Gm50163	predicted gene, 50163	291	0.49

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rreb1

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.2	0.5	GO:0010046	response to mycotoxin(GO:0010046)
0.1	0.4	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.1	0.4	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.1	0.5	GO:1903275	positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.1	0.7	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.4	GO:2000664	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.1	0.3	GO:2000847	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1	0.6	GO:0051775	response to redox state(GO:0051775)
0.1	0.2	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	0.2	GO:0042167	heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)
0.1	0.2	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.1	0.2	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1	0.2	GO:0061043	regulation of vascular wound healing(GO:0061043)
0.1	0.2	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.1	0.3	GO:0003383	apical constriction(GO:0003383)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.2	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	0.4	GO:0090527	actin filament reorganization(GO:0090527)
0.1	0.2	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.1	0.3	GO:0032484	Ral protein signal transduction(GO:0032484)
0.1	0.2	GO:0006553	lysine metabolic process(GO:0006553)
0.1	0.2	GO:0018094	protein polyglycylation(GO:0018094)
0.1	0.3	GO:0033578	protein glycosylation in Golgi(GO:0033578)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.1	0.2	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1	0.3	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.1	0.2	GO:0031581	hemidesmosome assembly(GO:0031581)
0.1	0.3	GO:0046984	regulation of hemoglobin biosynthetic process(GO:0046984)
0.1	0.3	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.1	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.2	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:1902683	regulation of receptor localization to synapse(GO:1902683)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0	0.2	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.0	GO:1902473	regulation of protein localization to synapse(GO:1902473)
0.0	0.3	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.2	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.3	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.0	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.2	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.2	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.2	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.3	GO:0046085	adenosine metabolic process(GO:0046085)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.1	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.2	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.2	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.3	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.3	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.2	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.1	GO:0009629	response to gravity(GO:0009629)
0.0	0.1	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.1	GO:0002254	kinin cascade(GO:0002254)
0.0	0.3	GO:1901978	positive regulation of cell cycle checkpoint(GO:1901978)
0.0	0.1	GO:0036295	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.2	GO:0046473	phosphatidic acid metabolic process(GO:0046473)
0.0	0.1	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.2	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.1	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
0.0	0.1	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.0	GO:0060449	bud elongation involved in lung branching(GO:0060449)
0.0	0.2	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.1	GO:0051660	establishment of centrosome localization(GO:0051660)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:0016103	diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.1	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.1	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0	0.1	GO:0036438	maintenance of lens transparency(GO:0036438)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0051365	cellular response to potassium ion starvation(GO:0051365)
0.0	0.2	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.2	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:1903261	regulation of serine phosphorylation of STAT3 protein(GO:1903261)
0.0	0.1	GO:0035425	autocrine signaling(GO:0035425)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.3	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:1900625	regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0	0.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.3	GO:2000310	regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0	0.3	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.0	0.1	GO:0048242	epinephrine transport(GO:0048241) epinephrine secretion(GO:0048242)
0.0	0.1	GO:0045472	response to ether(GO:0045472)
0.0	0.1	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.1	GO:0033058	directional locomotion(GO:0033058)
0.0	0.1	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.0	0.0	GO:1902661	regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0	0.1	GO:0060066	oviduct development(GO:0060066)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:0046449	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.0	0.1	GO:0070587	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0	0.1	GO:0052055	modulation by symbiont of host molecular function(GO:0052055)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.3	GO:0080111	DNA demethylation(GO:0080111)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:0040009	regulation of growth rate(GO:0040009)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.2	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.2	GO:0042447	hormone catabolic process(GO:0042447)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.1	GO:0009071	serine family amino acid catabolic process(GO:0009071)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.2	GO:0097341	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0030300	regulation of intestinal cholesterol absorption(GO:0030300)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.0	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0	0.4	GO:0070207	protein homotrimerization(GO:0070207)
0.0	0.2	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.2	GO:0016559	peroxisome fission(GO:0016559)
0.0	0.1	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.2	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.1	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.1	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.2	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0001672	regulation of chromatin assembly or disassembly(GO:0001672)
0.0	0.2	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0002681	somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0	0.1	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.0	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.2	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.0	GO:0009698	phenylpropanoid metabolic process(GO:0009698)
0.0	0.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0097090	presynaptic membrane organization(GO:0097090)
0.0	0.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.0	GO:1903984	positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.1	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0	0.1	GO:0042420	dopamine catabolic process(GO:0042420)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.0	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:1901525	negative regulation of macromitophagy(GO:1901525)
0.0	0.1	GO:0071985	multivesicular body sorting pathway(GO:0071985)
0.0	0.0	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.0	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0000052	citrulline metabolic process(GO:0000052)
0.0	0.0	GO:0035262	gonad morphogenesis(GO:0035262)
0.0	0.1	GO:0071361	cellular response to ethanol(GO:0071361)
0.0	0.0	GO:1903659	complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.0	GO:0090315	negative regulation of protein targeting to membrane(GO:0090315)
0.0	0.0	GO:1901165	positive regulation of trophoblast cell migration(GO:1901165)
0.0	0.4	GO:0001706	endoderm formation(GO:0001706)
0.0	0.0	GO:0010873	positive regulation of cholesterol esterification(GO:0010873)
0.0	0.0	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.3	GO:0002021	response to dietary excess(GO:0002021)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0071038	nuclear polyadenylation-dependent tRNA catabolic process(GO:0071038)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.0	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.1	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	0.1	GO:0060447	bud outgrowth involved in lung branching(GO:0060447)
0.0	0.2	GO:0002347	response to tumor cell(GO:0002347)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.0	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	0.1	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.1	GO:0035455	response to interferon-alpha(GO:0035455)
0.0	0.0	GO:1904729	regulation of intestinal lipid absorption(GO:1904729)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.0	GO:0002904	positive regulation of B cell apoptotic process(GO:0002904)
0.0	0.0	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.0	GO:0019530	taurine metabolic process(GO:0019530)
0.0	0.1	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:0002439	chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0	0.0	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.1	GO:0070498	interleukin-1-mediated signaling pathway(GO:0070498)
0.0	0.2	GO:0042572	retinol metabolic process(GO:0042572)
0.0	0.0	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.1	GO:0071236	cellular response to antibiotic(GO:0071236)
0.0	0.0	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.1	GO:0090239	regulation of histone H4 acetylation(GO:0090239)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.0	GO:2000065	negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.0	GO:0071314	cellular response to cocaine(GO:0071314)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0035990	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.0	GO:0061419	positive regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061419)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.0	GO:0010637	negative regulation of mitochondrial fusion(GO:0010637)
0.0	0.0	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.1	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:0061144	alveolar secondary septum development(GO:0061144)
0.0	0.1	GO:0072378	blood coagulation, fibrin clot formation(GO:0072378)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.2	GO:0030262	cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.0	0.1	GO:0008215	spermine metabolic process(GO:0008215)
0.0	0.0	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.1	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.0	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0072161	mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0	0.0	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.0	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:0070368	positive regulation of hepatocyte differentiation(GO:0070368)
0.0	0.1	GO:0050872	white fat cell differentiation(GO:0050872)
0.0	0.0	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.2	GO:0048535	lymph node development(GO:0048535)
0.0	0.1	GO:0045019	negative regulation of nitric oxide biosynthetic process(GO:0045019) negative regulation of nitric oxide metabolic process(GO:1904406)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.2	GO:0034340	response to type I interferon(GO:0034340)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0044326	dendritic spine neck(GO:0044326)
0.1	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0005952	cAMP-dependent protein kinase complex(GO:0005952)
0.0	0.5	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.2	GO:0097422	tubular endosome(GO:0097422)
0.0	0.2	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.2	GO:0097342	ripoptosome(GO:0097342)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.3	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.2	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	0.1	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.1	GO:0097058	CRLF-CLCF1 complex(GO:0097058)
0.0	0.1	GO:0044354	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.4	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0032010	phagolysosome(GO:0032010)
0.0	0.1	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.2	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.0	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.0	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.0	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.0	GO:0038037	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.2	GO:0002178	palmitoyltransferase complex(GO:0002178)
0.0	0.2	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.0	GO:0070552	BRISC complex(GO:0070552)
0.0	0.0	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.0	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.1	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.0	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.0	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.0	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0005942	phosphatidylinositol 3-kinase complex(GO:0005942)
0.0	0.1	GO:0043203	axon hillock(GO:0043203)
0.0	0.0	GO:0000120	RNA polymerase I transcription factor complex(GO:0000120)
0.0	0.1	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.0	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.0	GO:0005610	laminin-5 complex(GO:0005610)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.8	GO:0019957	C-C chemokine binding(GO:0019957)
0.1	0.1	GO:0008865	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1	0.6	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	0.2	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.1	0.2	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1	0.2	GO:0016647	oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.3	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	0.2	GO:0030350	iron-responsive element binding(GO:0030350)
0.1	0.2	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.2	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.2	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.2	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.2	GO:1904288	BAT3 complex binding(GO:1904288)
0.0	0.2	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.3	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.6	GO:1900750	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.4	GO:0004000	adenosine deaminase activity(GO:0004000)
0.0	0.3	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.1	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.2	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.2	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0051733	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.4	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.6	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.3	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.2	GO:0030368	interleukin-17 receptor activity(GO:0030368)
0.0	0.3	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.2	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	1.3	GO:0017022	myosin binding(GO:0017022)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.3	GO:0000993	RNA polymerase II core binding(GO:0000993)
0.0	0.1	GO:0034824	enoyl-[acyl-carrier-protein] reductase activity(GO:0016631) 2,3-dihydroxy-2,3-dihydro-phenylpropionate dehydrogenase activity(GO:0018498) cis-2,3-dihydrodiol DDT dehydrogenase activity(GO:0018499) trans-9R,10R-dihydrodiolphenanthrene dehydrogenase activity(GO:0018500) cis-chlorobenzene dihydrodiol dehydrogenase activity(GO:0018501) 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase activity(GO:0018502) trans-1,2-dihydrodiolphenanthrene dehydrogenase activity(GO:0018503) 3,4-dihydroxy-3,4-dihydrofluorene dehydrogenase activity(GO:0034790) benzo(a)pyrene-trans-11,12-dihydrodiol dehydrogenase activity(GO:0034805) benzo(a)pyrene-cis-4,5-dihydrodiol dehydrogenase activity(GO:0034809) citronellyl-CoA dehydrogenase activity(GO:0034824) menthone dehydrogenase activity(GO:0034838) phthalate 3,4-cis-dihydrodiol dehydrogenase activity(GO:0034912) cinnamate reductase activity(GO:0043786) NADPH-dependent curcumin reductase activity(GO:0052849) NADPH-dependent dihydrocurcumin reductase activity(GO:0052850)
0.0	0.1	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.3	GO:0008253	5'-nucleotidase activity(GO:0008253)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.5	GO:0042056	chemoattractant activity(GO:0042056)
0.0	0.1	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.1	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.1	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0005127	ciliary neurotrophic factor receptor binding(GO:0005127)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0045505	dynein intermediate chain binding(GO:0045505)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.1	GO:0004791	thioredoxin-disulfide reductase activity(GO:0004791)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.0	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0035014	phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.0	0.0	GO:0019776	Atg8 ligase activity(GO:0019776)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.0	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0016813	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0	0.1	GO:0004111	creatine kinase activity(GO:0004111)
0.0	0.1	GO:0001884	pyrimidine nucleoside binding(GO:0001884)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.1	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.1	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.2	GO:0017075	syntaxin-1 binding(GO:0017075)
0.0	0.1	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.3	GO:0004115	3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.0	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.1	GO:0043023	ribosomal large subunit binding(GO:0043023)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.2	GO:0042166	acetylcholine binding(GO:0042166)
0.0	0.0	GO:0004619	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.2	PID CDC42 PATHWAY	CDC42 signaling events
0.1	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
1.0	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.1	PID AR NONGENOMIC PATHWAY	Nongenotropic Androgen signaling
0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.2	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.3	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.2	ST GA12 PATHWAY	G alpha 12 Pathway
0.3	ST TUMOR NECROSIS FACTOR PATHWAY	Tumor Necrosis Factor Pathway.
0.0	PID IFNG PATHWAY	IFN-gamma pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.0	REACTOME BOTULINUM NEUROTOXICITY	Genes involved in Botulinum neurotoxicity
0.0	1.0	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.5	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.4	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.1	REACTOME PLC BETA MEDIATED EVENTS	Genes involved in PLC beta mediated events
0.0	0.2	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS	Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0	0.1	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0	0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.4	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.2	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.0	REACTOME INFLUENZA LIFE CYCLE	Genes involved in Influenza Life Cycle
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.0	REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY	Genes involved in TRAF3-dependent IRF activation pathway
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.0	REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1	Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.0	0.1	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.1	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.2	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0	0.1	REACTOME P75 NTR RECEPTOR MEDIATED SIGNALLING	Genes involved in p75 NTR receptor-mediated signalling
0.0	0.1	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex

Results for Rreb1

Z-value: 2.10

Motif logo

Transcription factors associated with Rreb1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Rreb1 motif across conditions

Conditions sorted by the z-value of the Rreb1 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rreb1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: