Project
ENCSR904DTN: DNase-seq of mouse liver in constant darkness
Navigation
Downloads
Logo

Results for Runx3

Z-value: 2.00

Motif logo

logo of

Transcription factors associated with Runx3

Gene Symbol Gene ID Gene Info
Runx3
ENSMUSG00000070691.4 runt related transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_135204278_135204439Runx3499220.0963260.758.8e-02Click!
chr4_135203380_135204093Runx3493000.0975350.582.3e-01Click!
chr4_135206185_135206602Runx3519570.0923840.562.5e-01Click!

Activity of the Runx3 motif across conditions

Conditions sorted by the z-value of the Runx3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_109993740_109993939 1.94 Gm34667
 predicted gene, 34667
 30034
 0.1
chr16_21613201_21613352 1.53 Vps8
 VPS8 CORVET complex subunit
 5430
 0.27
chr12_41247016_41247167 1.17 Gm47376
 predicted gene, 47376
 100999
 0.07
chr15_102192910_102193280 0.98 Csad
 cysteine sulfinic acid decarboxylase
 1036
 0.35
chr9_103066985_103067146 0.92 Gm47468
 predicted gene, 47468
 18461
 0.14
chr10_7976561_7976927 0.91 Tab2
 TGF-beta activated kinase 1/MAP3K7 binding protein 2
 20514
 0.19
chr13_93621073_93621244 0.90 Gm15622
 predicted gene 15622
 4224
 0.19
chr3_123104065_123104239 0.90 Synpo2
 synaptopodin 2
 8658
 0.16
chr10_95544966_95545117 0.88 Ube2n
 ubiquitin-conjugating enzyme E2N
 3528
 0.16
chr2_77155937_77156088 0.88 Ccdc141
 coiled-coil domain containing 141
 14564
 0.21
chr15_99093772_99093973 0.81 Dnajc22
 DnaJ heat shock protein family (Hsp40) member C22
 702
 0.47
chr6_88717841_88718269 0.80 Mgll
 monoglyceride lipase
 6357
 0.14
chr2_103600397_103600730 0.80 Abtb2
 ankyrin repeat and BTB (POZ) domain containing 2
 34253
 0.15
chr7_81542702_81542853 0.80 Gm37829
 predicted gene, 37829
 10256
 0.1
chr4_86664611_86664778 0.74 Plin2
 perilipin 2
 1031
 0.52
chr6_85803570_85803735 0.74 Nat8f6
 N-acetyltransferase 8 (GCN5-related) family member 6
 6211
 0.09
chr5_9103732_9103883 0.72 Tmem243
 transmembrane protein 243, mitochondrial
 3060
 0.23
chr7_80666924_80667352 0.72 Crtc3
 CREB regulated transcription coactivator 3
 21739
 0.15
chr6_85702238_85702435 0.70 Nat8f7
 N-acetyltransferase 8 (GCN5-related) family member 7
 5522
 0.12
chr4_46657221_46657388 0.67 Tbc1d2
 TBC1 domain family, member 2
 7095
 0.21
chr16_50764320_50764471 0.65 1700116B05Rik
 RIKEN cDNA 1700116B05 gene
 19014
 0.18
chr15_82455207_82455652 0.60 Cyp2d9
 cytochrome P450, family 2, subfamily d, polypeptide 9
 141
 0.87
chr5_120566729_120566934 0.60 2510016D11Rik
 RIKEN cDNA 2510016D11 gene
 13792
 0.09
chr2_161090855_161091012 0.59 Chd6
 chromodomain helicase DNA binding protein 6
 18071
 0.18
chr7_35802685_35802845 0.59 E130304I02Rik
 RIKEN cDNA E130304I02 gene
 172
 0.52
chr4_100401449_100401626 0.58 Gm12706
 predicted gene 12706
 39478
 0.18
chr15_82397705_82398277 0.58 Cyp2d11
 cytochrome P450, family 2, subfamily d, polypeptide 11
 3969
 0.07
chr1_39545677_39545839 0.57 Snord89
 small nucleolar RNA, C/D box 89
 3096
 0.14
chr18_20980846_20980997 0.57 Rnf125
 ring finger protein 125
 19449
 0.18
chr11_67526441_67526592 0.57 Gas7
 growth arrest specific 7
 20638
 0.21
chr8_71535881_71536032 0.57 Bst2
 bone marrow stromal cell antigen 2
 1375
 0.2
chr2_172477517_172477864 0.57 Fam209
 family with sequence similarity 209
 5170
 0.15
chr16_17885845_17885996 0.56 Dgcr2
 DiGeorge syndrome critical region gene 2
 5673
 0.09
chr18_63597933_63598104 0.56 Gm24848
 predicted gene, 24848
 13282
 0.18
chr5_125137828_125138031 0.55 Ncor2
 nuclear receptor co-repressor 2
 13029
 0.2
chr11_70409620_70409854 0.53 Pelp1
 proline, glutamic acid and leucine rich protein 1
 291
 0.78
chr4_101416398_101416601 0.53 Ak4
 adenylate kinase 4
 2778
 0.2
chr7_49633783_49633973 0.53 Dbx1
 developing brain homeobox 1
 2971
 0.33
chr1_182602082_182602275 0.53 Capn8
 calpain 8
 37140
 0.13
chr15_80711397_80711548 0.52 Tnrc6b
 trinucleotide repeat containing 6b
 159
 0.88
chr4_155320479_155320646 0.51 Prkcz
 protein kinase C, zeta
 19391
 0.14
chr15_10953321_10953904 0.51 C1qtnf3
 C1q and tumor necrosis factor related protein 3
 1255
 0.4
chr1_193617502_193617686 0.51 Mir205hg
 Mir205 host gene
 107420
 0.06
chr2_126574664_126574815 0.50 Slc27a2
 solute carrier family 27 (fatty acid transporter), member 2
 9979
 0.18
chr17_24470568_24470947 0.50 Pgp
 phosphoglycolate phosphatase
 322
 0.51
chr6_5190649_5191077 0.50 Pon1
 paraoxonase 1
 2900
 0.26
chr15_36471981_36472313 0.50 Ankrd46
 ankyrin repeat domain 46
 24568
 0.12
chr8_109705135_109705296 0.49 Zfp821
 zinc finger protein 821
 331
 0.85
chr5_135090387_135090722 0.49 Mlxipl
 MLX interacting protein-like
 664
 0.5
chr12_26398692_26398891 0.48 Rnf144a
 ring finger protein 144A
 7656
 0.16
chr13_98946494_98946645 0.48 Gm35215
 predicted gene, 35215
 653
 0.6
chr14_73630476_73630939 0.47 Gm21750
 predicted gene, 21750
 30518
 0.15
chr13_119966643_119967735 0.47 Gm20784
 predicted gene, 20784
 4945
 0.11
chr9_48826985_48827136 0.47 Zbtb16
 zinc finger and BTB domain containing 16
 8885
 0.24
chr11_60728592_60728763 0.46 Mir5100
 microRNA 5100
 14
 0.73
chr11_69902083_69902235 0.45 Neurl4
 neuralized E3 ubiquitin protein ligase 4
 3
 0.9
chr12_98628262_98628451 0.45 Spata7
 spermatogenesis associated 7
 159
 0.93
chr7_130710473_130710636 0.45 Tacc2
 transforming, acidic coiled-coil containing protein 2
 3123
 0.24
chr2_69226745_69226961 0.45 G6pc2
 glucose-6-phosphatase, catalytic, 2
 6825
 0.15
chr3_22168181_22168357 0.44 Tbl1xr1
 transducin (beta)-like 1X-linked receptor 1
 19327
 0.21
chr11_75678792_75678954 0.44 Crk
 v-crk avian sarcoma virus CT10 oncogene homolog
 386
 0.8
chr17_27556354_27556505 0.44 Hmga1
 high mobility group AT-hook 1
 68
 0.51
chr14_69171500_69171815 0.43 Nkx2-6
 NK2 homeobox 6
 145
 0.57
chr2_72475881_72476264 0.43 Cdca7
 cell division cycle associated 7
 87
 0.98
chr12_55487707_55488022 0.43 Nfkbia
 nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
 3946
 0.21
chr12_87300349_87300500 0.42 Ism2
 isthmin 2
 719
 0.52
chr11_120555335_120555502 0.42 Ppp1r27
 protein phosphatase 1, regulatory subunit 27
 4286
 0.07
chr5_132467140_132467305 0.42 Auts2
 autism susceptibility candidate 2
 17862
 0.12
chr3_149546578_149546753 0.42 Gm30382
 predicted gene, 30382
 101364
 0.08
chr5_145852474_145852695 0.42 Cyp3a11
 cytochrome P450, family 3, subfamily a, polypeptide 11
 24107
 0.13
chr9_124281840_124282030 0.41 Gm39469
 predicted gene, 39469
 204
 0.93
chr8_105347302_105347515 0.41 Fhod1
 formin homology 2 domain containing 1
 501
 0.52
chr2_132263417_132263641 0.41 Cds2
 CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 2
 288
 0.88
chrX_74305335_74305495 0.40 Gdi1
 guanosine diphosphate (GDP) dissociation inhibitor 1
 102
 0.89
chr12_26469202_26469522 0.40 Cmpk2
 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
 158
 0.94
chr15_75974567_75974718 0.40 Zfp707
 zinc finger protein 707
 1859
 0.15
chr8_61574352_61574983 0.40 Palld
 palladin, cytoskeletal associated protein
 16472
 0.25
chr2_118490490_118490877 0.40 Gm13983
 predicted gene 13983
 6506
 0.16
chr4_41713984_41714147 0.40 Rpp25l
 ribonuclease P/MRP 25 subunit-like
 531
 0.59
chr2_4651833_4652008 0.40 Prpf18
 pre-mRNA processing factor 18
 161
 0.96
chr5_76184387_76184581 0.40 Tmem165
 transmembrane protein 165
 534
 0.73
chr13_33003844_33004060 0.40 Serpinb9
 serine (or cysteine) peptidase inhibitor, clade B, member 9
 589
 0.64
chr2_154855271_154855679 0.39 Eif2s2
 eukaryotic translation initiation factor 2, subunit 2 (beta)
 37307
 0.13
chr3_58593720_58593871 0.39 Selenot
 selenoprotein T
 17097
 0.14
chr8_48492721_48492872 0.39 Tenm3
 teneurin transmembrane protein 3
 62517
 0.14
chr5_112282209_112282362 0.38 Tpst2
 protein-tyrosine sulfotransferase 2
 5578
 0.13
chr16_91238840_91239051 0.38 Olig2
 oligodendrocyte transcription factor 2
 13488
 0.11
chr9_108792795_108793094 0.38 Gm23034
 predicted gene, 23034
 2444
 0.14
chr19_41846454_41846665 0.37 Frat2
 frequently rearranged in advanced T cell lymphomas 2
 1573
 0.3
chrX_140568088_140568285 0.37 AL683809.1
 TSC22 domain family, member 3 (Tsc22d3), pseuodgene
 15413
 0.17
chr4_12140361_12140643 0.37 Rbm12b1
 RNA binding motif protein 12 B1
 185
 0.91
chr6_86820856_86821008 0.37 Anxa4
 annexin A4
 27348
 0.1
chr11_83853555_83853722 0.37 Hnf1b
 HNF1 homeobox B
 678
 0.62
chr7_43444450_43444615 0.36 Etfb
 electron transferring flavoprotein, beta polypeptide
 382
 0.4
chr8_70131574_70131799 0.36 Nr2c2ap
 nuclear receptor 2C2-associated protein
 339
 0.73
chr8_109869084_109869235 0.36 Phlpp2
 PH domain and leucine rich repeat protein phosphatase 2
 548
 0.48
chr5_125323526_125323720 0.36 Gm42633
 predicted gene 42633
 2179
 0.22
chr8_121307859_121308016 0.36 Gm26815
 predicted gene, 26815
 48899
 0.13
chr15_99034485_99034683 0.36 Tuba1c
 tubulin, alpha 1C
 4263
 0.11
chr10_44527174_44527473 0.36 Prdm1
 PR domain containing 1, with ZNF domain
 1178
 0.46
chr10_53928699_53928881 0.36 Man1a
 mannosidase 1, alpha
 48325
 0.16
chr3_94399233_94399394 0.35 Lingo4
 leucine rich repeat and Ig domain containing 4
 796
 0.33
chr18_50137858_50138009 0.35 Cd63-ps
 CD63 antigen, pseudogene
 3138
 0.23
chr14_34618565_34618885 0.35 Opn4
 opsin 4 (melanopsin)
 18583
 0.11
chr14_61354089_61354266 0.35 Ebpl
 emopamil binding protein-like
 6143
 0.13
chr11_20733626_20734042 0.35 Gm12036
 predicted gene 12036
 4414
 0.21
chr12_30200282_30200708 0.34 Sntg2
 syntrophin, gamma 2
 840
 0.72
chr5_35030633_35030784 0.34 Gm43791
 predicted gene 43791
 2737
 0.18
chr10_7211859_7212010 0.34 Cnksr3
 Cnksr family member 3
 303
 0.94
chr4_48046634_48046887 0.33 Nr4a3
 nuclear receptor subfamily 4, group A, member 3
 1529
 0.46
chr4_134879692_134879843 0.33 Rhd
 Rh blood group, D antigen
 43
 0.97
chr12_113221349_113221516 0.33 Gm25622
 predicted gene, 25622
 7283
 0.14
chr4_100129098_100129249 0.33 Gm12701
 predicted gene 12701
 9552
 0.23
chr10_122986042_122986255 0.32 D630033A02Rik
 RIKEN cDNA D630033A02 gene
 317
 0.58
chr4_12089474_12090115 0.32 Tmem67
 transmembrane protein 67
 226
 0.62
chr4_135270319_135270473 0.32 Clic4
 chloride intracellular channel 4 (mitochondrial)
 2418
 0.22
chr10_127513114_127513548 0.32 Ndufa4l2
 Ndufa4, mitochondrial complex associated like 2
 1636
 0.21
chr17_30199906_30200207 0.32 Zfand3
 zinc finger, AN1-type domain 3
 2480
 0.27
chr8_33930013_33930185 0.32 Rbpms
 RNA binding protein gene with multiple splicing
 236
 0.92
chr10_25621751_25621928 0.32 Gm36908
 predicted gene, 36908
 276
 0.91
chr19_41847242_41847459 0.32 Frat2
 frequently rearranged in advanced T cell lymphomas 2
 782
 0.55
chr11_120086018_120086485 0.32 Cep131
 centrosomal protein 131
 576
 0.57
chr11_109718016_109718204 0.32 Fam20a
 family with sequence similarity 20, member A
 4146
 0.22
chr4_32240053_32240204 0.32 Bach2
 BTB and CNC homology, basic leucine zipper transcription factor 2
 1051
 0.54
chr12_84939224_84939386 0.32 Arel1
 apoptosis resistant E3 ubiquitin protein ligase 1
 4073
 0.15
chr3_96457950_96458248 0.31 Gm10685
 predicted gene 10685
 110
 0.87
chr3_138422238_138422402 0.31 Adh4
 alcohol dehydrogenase 4 (class II), pi polypeptide
 6825
 0.14
chr1_184785241_184785692 0.31 Mtarc1
 mitochondrial amidoxime reducing component 1
 23387
 0.12
chr15_46598446_46598597 0.31 4930548G14Rik
 RIKEN cDNA 4930548G14 gene
 24784
 0.25
chr13_59004016_59004334 0.31 Gm34245
 predicted gene, 34245
 74121
 0.08
chr4_59311382_59311545 0.31 Susd1
 sushi domain containing 1
 4503
 0.24
chr16_91362482_91362649 0.31 Ifnar2
 interferon (alpha and beta) receptor 2
 10218
 0.11
chr4_132535706_132535867 0.31 Dnajc8
 DnaJ heat shock protein family (Hsp40) member C8
 127
 0.91
chr3_96452393_96452678 0.31 BC107364
 cDNA sequence BC107364
 229
 0.76
chr11_120466994_120467145 0.31 Arl16
 ADP-ribosylation factor-like 16
 205
 0.71
chr10_81135573_81135724 0.31 Zbtb7a
 zinc finger and BTB domain containing 7a
 428
 0.63
chr2_60383071_60383222 0.31 Ly75
 lymphocyte antigen 75
 85
 0.97
chr13_60665524_60665709 0.30 Gm48583
 predicted gene, 48583
 23826
 0.15
chr5_142782966_142783117 0.30 Tnrc18
 trinucleotide repeat containing 18
 5482
 0.21
chr4_128981174_128981543 0.30 Ak2
 adenylate kinase 2
 10600
 0.15
chr17_25507894_25508055 0.30 Gm33727
 predicted gene, 33727
 10611
 0.09
chr8_93227828_93228167 0.30 Ces1e
 carboxylesterase 1E
 1621
 0.29
chr8_85007833_85007986 0.30 Best2
 bestrophin 2
 5682
 0.06
chr4_76343359_76343684 0.30 Ptprd
 protein tyrosine phosphatase, receptor type, D
 722
 0.77
chr5_43781403_43781714 0.30 Fbxl5
 F-box and leucine-rich repeat protein 5
 542
 0.46
chr14_63248471_63248829 0.30 Gata4
 GATA binding protein 4
 3379
 0.22
chrX_13845208_13845423 0.30 Cask
 calcium/calmodulin-dependent serine protein kinase (MAGUK family)
 773
 0.75
chr11_20561304_20561596 0.30 Gm12035
 predicted gene 12035
 13739
 0.2
chr10_30200517_30200678 0.30 Cenpw
 centromere protein W
 37
 0.98
chr19_10239849_10240587 0.29 Myrf
 myelin regulatory factor
 386
 0.77
chr6_17694870_17695095 0.29 St7
 suppression of tumorigenicity 7
 815
 0.54
chr7_31053117_31053317 0.29 Fxyd1
 FXYD domain-containing ion transport regulator 1
 95
 0.91
chr17_56104393_56104561 0.29 Hdgfl2
 HDGF like 2
 4915
 0.09
chr19_23105417_23105568 0.29 2410080I02Rik
 RIKEN cDNA 2410080I02 gene
 29408
 0.13
chr5_102068968_102069164 0.29 Wdfy3
 WD repeat and FYVE domain containing 3
 855
 0.46
chr17_83897414_83897589 0.29 1810073O08Rik
 RIKEN cDNA 1810073O08 gene
 20436
 0.13
chr5_100673907_100674085 0.28 Coq2
 coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
 160
 0.94
chr16_59594968_59595140 0.28 Crybg3
 beta-gamma crystallin domain containing 3
 5925
 0.21
chr12_59235308_59235463 0.28 Gm27284
 predicted gene, 27284
 1791
 0.28
chr3_107631354_107631565 0.28 Gm10961
 predicted gene 10961
 137
 0.63
chr2_103472788_103473367 0.28 Cat
 catalase
 12048
 0.18
chr2_26922374_26922531 0.28 Surf2
 surfeit gene 2
 5024
 0.08
chr15_76606976_76607461 0.28 Cpsf1
 cleavage and polyadenylation specific factor 1
 271
 0.77
chr1_131971555_131972013 0.28 Slc45a3
 solute carrier family 45, member 3
 1175
 0.35
chr6_113494556_113494760 0.28 Creld1
 cysteine-rich with EGF-like domains 1
 2639
 0.11
chr7_132852781_132852967 0.28 Eef1akmt2
 EEF1A lysine methyltransferase 2
 201
 0.91
chr10_89770056_89770207 0.28 Uhrf1bp1l
 UHRF1 (ICBP90) binding protein 1-like
 17069
 0.18
chr9_61914762_61915200 0.28 Rplp1
 ribosomal protein, large, P1
 439
 0.83
chr8_27054619_27054804 0.27 Plpbp
 pyridoxal phosphate binding protein
 3937
 0.13
chr1_139422425_139422762 0.27 Zbtb41
 zinc finger and BTB domain containing 41
 211
 0.92
chr7_110942462_110942613 0.27 Mrvi1
 MRV integration site 1
 3650
 0.23
chr14_20995157_20995320 0.27 Vcl
 vinculin
 26765
 0.17
chr10_80702834_80702996 0.27 Izumo4
 IZUMO family member 4
 144
 0.87
chr11_116187883_116188093 0.27 Acox1
 acyl-Coenzyme A oxidase 1, palmitoyl
 1587
 0.21
chr4_145774583_145774829 0.27 Gm13243
 predicted gene 13243
 13
 0.94
chr1_74723320_74723471 0.27 Cyp27a1
 cytochrome P450, family 27, subfamily a, polypeptide 1
 9821
 0.12
chr9_63550824_63550989 0.27 Gm16759
 predicted gene, 16759
 19554
 0.18
chr7_29155799_29155976 0.27 Fam98c
 family with sequence similarity 98, member C
 168
 0.52
chr7_19095153_19095353 0.27 Six5
 sine oculis-related homeobox 5
 659
 0.44
chr1_74016328_74016481 0.27 Tns1
 tensin 1
 18
 0.98
chr2_103595080_103595270 0.27 Abtb2
 ankyrin repeat and BTB (POZ) domain containing 2
 28865
 0.16
chr17_44256731_44256898 0.27 Clic5
 chloride intracellular channel 5
 19708
 0.26
chr2_153632897_153633072 0.27 Commd7
 COMM domain containing 7
 203
 0.93
chr1_93128050_93128201 0.26 Gm28086
 predicted gene 28086
 4022
 0.15
chr9_96718101_96718252 0.26 Zbtb38
 zinc finger and BTB domain containing 38
 1389
 0.38
chr2_92376664_92376833 0.26 Pex16
 peroxisomal biogenesis factor 16
 1189
 0.28
chr6_66896024_66896206 0.26 Gng12
 guanine nucleotide binding protein (G protein), gamma 12
 282
 0.6
chr6_141327961_141328118 0.26 Gm10400
 predicted gene 10400
 12514
 0.24
chr7_132811347_132811663 0.25 Fam53b
 family with sequence similarity 53, member B
 1590
 0.34
chr16_24629324_24629735 0.25 Lpp
 LIM domain containing preferred translocation partner in lipoma
 92326
 0.08
chr17_24349257_24349433 0.25 Abca17
 ATP-binding cassette, sub-family A (ABC1), member 17
 1684
 0.2
chr10_28387713_28387881 0.25 Ptprk
 protein tyrosine phosphatase, receptor type, K
 172354
 0.03
chr1_90238643_90238822 0.25 Gm38277
 predicted gene, 38277
 10206
 0.16
chr3_8961467_8961864 0.25 Tpd52
 tumor protein D52
 588
 0.76
chr16_15888920_15889238 0.25 Cebpd
 CCAAT/enhancer binding protein (C/EBP), delta
 663
 0.71
chr5_125389673_125389844 0.25 Ubc
 ubiquitin C
 256
 0.64
chr9_62355457_62355637 0.25 Anp32a
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 10748
 0.2
chr11_60727211_60727861 0.24 Flii
 flightless I actin binding protein
 273
 0.67
chr10_93432561_93432735 0.24 Mir7688
 microRNA 7688
 459
 0.78
chr5_38260278_38260440 0.24 Tmem128
 transmembrane protein 128
 12
 0.97

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Runx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0046075 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.4 GO:0009093 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.4 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.3 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.1 0.3 GO:0032286 central nervous system myelin maintenance(GO:0032286)
0.1 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.1 0.3 GO:0010255 carbohydrate mediated signaling(GO:0009756) hexose mediated signaling(GO:0009757) sugar mediated signaling pathway(GO:0010182) glucose mediated signaling pathway(GO:0010255)
0.1 0.4 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.1 0.3 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.2 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.1 0.2 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.3 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.2 GO:0033668 negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.1 0.3 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.1 0.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 0.2 GO:1900625 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:0009838 abscission(GO:0009838)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.4 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:0060211 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0070384 Harderian gland development(GO:0070384)
0.0 0.1 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0 0.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 0.1 GO:0006067 ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:0035461 vitamin transmembrane transport(GO:0035461)
0.0 0.2 GO:0071267 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.1 GO:0072205 metanephric collecting duct development(GO:0072205)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.4 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.0 0.2 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.3 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0045630 positive regulation of T-helper 2 cell differentiation(GO:0045630)
0.0 0.2 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.2 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.1 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0 0.2 GO:0006273 lagging strand elongation(GO:0006273)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.2 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.1 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.2 GO:0032075 positive regulation of nuclease activity(GO:0032075)
0.0 0.3 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.1 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.1 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.1 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.1 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.1 GO:0010990 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.3 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0036302 atrioventricular canal development(GO:0036302)
0.0 0.1 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:2000474 regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.1 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.2 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.0 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0060842 arterial endothelial cell differentiation(GO:0060842)
0.0 0.1 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.1 GO:1990000 amyloid fibril formation(GO:1990000)
0.0 0.1 GO:0097503 sialylation(GO:0097503)
0.0 0.3 GO:0097237 cellular response to toxic substance(GO:0097237)
0.0 0.1 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.0 GO:0009202 deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.0 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.2 GO:0070129 regulation of mitochondrial translation(GO:0070129)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.0 0.0 GO:0090360 platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0019934 cGMP-mediated signaling(GO:0019934)
0.0 0.0 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.2 GO:0032211 negative regulation of telomere maintenance via telomerase(GO:0032211)
0.0 0.1 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.1 GO:0046929 negative regulation of neurotransmitter secretion(GO:0046929)
0.0 0.0 GO:0006678 glucosylceramide metabolic process(GO:0006678)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.0 GO:0046909 intermembrane transport(GO:0046909)
0.0 0.1 GO:2000052 positive regulation of non-canonical Wnt signaling pathway(GO:2000052)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.2 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.0 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.0 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0 0.1 GO:0051014 actin filament severing(GO:0051014)
0.0 0.1 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.0 0.1 GO:0046033 AMP metabolic process(GO:0046033)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.0 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.1 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.8 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.0 GO:2000143 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.2 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.0 GO:0061197 fungiform papilla morphogenesis(GO:0061197) fungiform papilla formation(GO:0061198)
0.0 0.1 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.0 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.4 GO:0006284 base-excision repair(GO:0006284)
0.0 0.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.0 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.0 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0 0.0 GO:1904220 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.0 GO:0042447 hormone catabolic process(GO:0042447)
0.0 0.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.0 GO:1901552 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.3 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.0 0.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.0 0.0 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0 0.0 GO:0072197 ureter morphogenesis(GO:0072197) metanephric nephron tubule formation(GO:0072289)
0.0 0.1 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0007184 SMAD protein import into nucleus(GO:0007184)
0.0 0.0 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0 0.0 GO:0070836 caveola assembly(GO:0070836)
0.0 0.0 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0044598 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0 0.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.0 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 0.4 GO:0033263 CORVET complex(GO:0033263)
0.1 0.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0070552 BRISC complex(GO:0070552)
0.0 0.2 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.2 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.2 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.2 GO:0005652 nuclear lamina(GO:0005652)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.1 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.1 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.0 GO:0000938 GARP complex(GO:0000938)
0.0 0.4 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.6 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.0 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.0 GO:0032021 NELF complex(GO:0032021)
0.0 0.0 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.4 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0000386 second spliceosomal transesterification activity(GO:0000386)
0.1 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.2 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1 0.2 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1 0.1 GO:0032564 dATP binding(GO:0032564)
0.1 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.4 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.0 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 0.2 GO:0050786 RAGE receptor binding(GO:0050786)
0.0 0.8 GO:0070330 aromatase activity(GO:0070330)
0.0 0.0 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.1 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0016623 aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.2 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.2 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.1 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0034944 pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0 0.2 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 0.1 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0005123 death receptor binding(GO:0005123)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.5 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.0 GO:0031433 telethonin binding(GO:0031433)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.0 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.0 0.0 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.5 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.1 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0004791 thioredoxin-disulfide reductase activity(GO:0004791)
0.0 0.1 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.0 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.1 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0051735 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.0 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.1 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.1 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 0.0 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.0 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0050649 testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0 0.0 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.0 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.4 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID SYNDECAN 2 PATHWAY Syndecan-2-mediated signaling events
0.0 0.2 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.2 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.2 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.1 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.2 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.1 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.0 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME FGFR1 LIGAND BINDING AND ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.1 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.1 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.1 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1