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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Rxrb

Z-value: 1.49

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Transcription factors associated with Rxrb

Gene Symbol	Gene ID	Gene Info
Rxrb Ensembl NCBI MGI UniProt	ENSMUSG00000039656.10	retinoid X receptor beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_34034257_34034421	Rxrb	431	0.489336	0.87	2.3e-02	Click!
chr17_34034024_34034193	Rxrb	200	0.753708	0.83	4.1e-02	Click!
chr17_34036736_34036891	Rxrb	350	0.583289	0.83	4.1e-02	Click!
chr17_34031956_34032112	Rxrb	162	0.560513	0.77	7.0e-02	Click!
chr17_34032274_34032442	Rxrb	43	0.825708	0.65	1.6e-01	Click!

Activity of the Rxrb motif across conditions

Conditions sorted by the z-value of the Rxrb motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_63555594_63556179	1.64	Gm16759	predicted gene, 16759	24534	0.17
chr9_65334133_65334359	1.56	Gm39363	predicted gene, 39363	1726	0.18
chr13_93618437_93618616	1.54	Gm15622	predicted gene 15622	6856	0.17
chr18_20989164_20989323	1.30	Rnf138	ring finger protein 138	12098	0.2
chr10_8185660_8185825	1.14	Gm30906	predicted gene, 30906	9611	0.28
chr16_26163678_26163843	1.09	P3h2	prolyl 3-hydroxylase 2	57976	0.15
chr17_28298917_28299090	1.07	Ppard	peroxisome proliferator activator receptor delta	5757	0.11
chr9_43673281_43673432	1.04	Gm5364	predicted gene 5364	9697	0.16
chr10_8086797_8087175	1.01	Gm48614	predicted gene, 48614	65694	0.11
chr1_181475618_181475786	1.00	Ccdc121	coiled-coil domain containing 121	35749	0.14
chr9_121909867_121910023	0.82	Ackr2	atypical chemokine receptor 2	3681	0.11
chr5_117999417_117999593	0.82	Fbxo21	F-box protein 21	20181	0.12
chr2_32678870_32679034	0.82	Gm26236	predicted gene, 26236	3843	0.08
chr11_100779250_100779403	0.80	Ghdc	GH3 domain containing	8369	0.11
chr12_26398692_26398891	0.78	Rnf144a	ring finger protein 144A	7656	0.16
chr11_7184254_7184557	0.77	Ccdc201	coiled coil domain 201	4164	0.2
chr9_110688995_110689492	0.76	Gm35715	predicted gene, 35715	14289	0.1
chr10_61337527_61337708	0.73	Pald1	phosphatase domain containing, paladin 1	4710	0.15
chr16_4087795_4087959	0.72	Crebbp	CREB binding protein	718	0.55
chr8_119442578_119443025	0.71	Necab2	N-terminal EF-hand calcium binding protein 2	3918	0.18
chr5_32141078_32141248	0.70	Fosl2	fos-like antigen 2	4990	0.17
chr6_16696398_16696549	0.69	Gm36669	predicted gene, 36669	81051	0.1
chr9_40639390_40639732	0.67	Gm48284	predicted gene, 48284	23175	0.1
chr13_98594899_98595134	0.67	Gm4815	predicted gene 4815	18485	0.12
chr6_42221324_42221475	0.67	Tas2r144	taste receptor, type 2, member 144	6071	0.14
chr13_51903671_51903822	0.64	Gadd45g	growth arrest and DNA-damage-inducible 45 gamma	57002	0.12
chr7_30361694_30362080	0.64	Lrfn3	leucine rich repeat and fibronectin type III domain containing 3	885	0.31
chr12_112119169_112119320	0.63	Aspg	asparaginase	710	0.56
chr15_100659267_100659476	0.62	Bin2	bridging integrator 2	7711	0.09
chr2_142878410_142878573	0.62	Kif16b	kinesin family member 16B	22953	0.2
chr13_53126019_53126208	0.62	Gm48336	predicted gene, 48336	97195	0.07
chr8_117324934_117325253	0.62	Cmip	c-Maf inducing protein	24077	0.22
chr5_137741871_137742022	0.61	Nyap1	neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1	339	0.75
chr14_51009711_51009870	0.61	Rnase10	ribonuclease, RNase A family, 10 (non-active)	1861	0.17
chr17_49314104_49314288	0.61	Gm17830	predicted gene, 17830	1236	0.46
chrX_129949506_129949684	0.61	Diaph2	diaphanous related formin 2	22938	0.28
chr5_117275916_117276216	0.61	Pebp1	phosphatidylethanolamine binding protein 1	11459	0.11
chr17_24355260_24355582	0.60	Abca3	ATP-binding cassette, sub-family A (ABC1), member 3	3319	0.12
chr11_108846628_108846779	0.59	Cep112it	centrosomal protein 112, intronic transcript	26370	0.19
chr11_109503914_109504065	0.58	Gm22378	predicted gene, 22378	4165	0.16
chr18_61383552_61383876	0.58	Gm25301	predicted gene, 25301	14099	0.13
chr11_7201738_7201912	0.58	Igfbp1	insulin-like growth factor binding protein 1	4043	0.2
chr6_72233377_72233606	0.57	Atoh8	atonal bHLH transcription factor 8	1046	0.49
chr2_71467270_71467440	0.57	Metap1d	methionyl aminopeptidase type 1D (mitochondrial)	13992	0.13
chr1_86287598_86287749	0.57	Gm16341	predicted gene 16341	13702	0.09
chr2_144224091_144224242	0.57	Gm5535	predicted gene 5535	16176	0.11
chr14_25527604_25527755	0.57	Mir3075	microRNA 3075	6760	0.18
chr10_79777048_79777199	0.57	Fstl3	follistatin-like 3	149	0.88
chr17_46832774_46832929	0.56	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	537	0.72
chr3_31079567_31079731	0.56	Skil	SKI-like	15409	0.17
chr16_28990306_28990479	0.56	Gm8253	predicted gene 8253	39037	0.19
chr13_104615047_104615206	0.56	2610204G07Rik	RIKEN cDNA 2610204G07 gene	69805	0.12
chr17_13662964_13663132	0.56	2700054A10Rik	RIKEN cDNA 2700054A10 gene	5843	0.16
chr13_104042799_104043089	0.55	Nln	neurolysin (metallopeptidase M3 family)	5302	0.23
chr10_41565244_41565415	0.54	5730435O14Rik	RIKEN cDNA 5730435O14 gene	2687	0.19
chr19_4436418_4436609	0.54	A930001C03Rik	RIKEN cDNA A930001C03 gene	2490	0.17
chr14_20226543_20226703	0.53	Gm48395	predicted gene, 48395	11121	0.12
chr10_41567217_41567368	0.53	5730435O14Rik	RIKEN cDNA 5730435O14 gene	724	0.57
chr16_37854675_37854827	0.53	n-R5s34	nuclear encoded rRNA 5S 34	31	0.96
chr9_63556376_63556553	0.53	Gm16759	predicted gene, 16759	25112	0.17
chr8_72495568_72495889	0.52	Gm17435	predicted gene, 17435	2784	0.12
chr4_138343562_138343727	0.52	Cda	cytidine deaminase	5	0.96
chr10_117417442_117417610	0.52	Gm40770	predicted gene, 40770	3622	0.17
chr11_75198029_75198186	0.51	Rtn4rl1	reticulon 4 receptor-like 1	4324	0.12
chr10_61341072_61341225	0.51	Pald1	phosphatase domain containing, paladin 1	1179	0.37
chr10_25618453_25618660	0.50	Gm36908	predicted gene, 36908	3007	0.25
chr18_76077358_76077509	0.50	Zbtb7c	zinc finger and BTB domain containing 7C	17975	0.19
chr19_61080476_61080639	0.50	Zfp950	zinc finger protein 950	36816	0.13
chr17_27781322_27781617	0.50	Rps2-ps9	ribosomal protein S2, pseudogene 9	2910	0.18
chr12_88818907_88819069	0.50	Nrxn3	neurexin III	23549	0.23
chr2_12148001_12148165	0.49	Itga8	integrin alpha 8	15531	0.2
chr15_83454522_83454702	0.49	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	9940	0.15
chr10_75932703_75932854	0.49	Mmp11	matrix metallopeptidase 11	276	0.52
chr8_119410544_119410695	0.49	Mlycd	malonyl-CoA decarboxylase	15721	0.14
chr15_76575014_76575219	0.49	Adck5	aarF domain containing kinase 5	1242	0.21
chr19_36629854_36630038	0.49	Hectd2os	Hectd2, opposite strand	3922	0.26
chr11_115180057_115180236	0.48	Nat9	N-acetyltransferase 9 (GCN5-related, putative)	6935	0.11
chr3_83028159_83028709	0.48	Fga	fibrinogen alpha chain	2219	0.23
chr10_59977591_59977907	0.48	Anapc16	anaphase promoting complex subunit 16	12634	0.16
chr1_71986156_71986328	0.48	Gm5528	predicted gene 5528	18046	0.16
chr4_33257682_33258147	0.47	Pnrc1	proline-rich nuclear receptor coactivator 1	9404	0.17
chr6_122249737_122249965	0.47	Mug-ps1	murinoglobulin, pseudogene 1	20791	0.13
chr12_28898423_28898586	0.47	Gm31508	predicted gene, 31508	11725	0.17
chr5_110596813_110596964	0.47	Galnt9	polypeptide N-acetylgalactosaminyltransferase 9	6633	0.15
chr1_88760195_88760369	0.47	Platr5	pluripotency associated transcript 5	5328	0.21
chr8_71294074_71294225	0.47	Haus8	4HAUS augmin-like complex, subunit 8	21215	0.12
chr6_39248996_39249577	0.46	Gm43479	predicted gene 43479	9172	0.15
chr9_78027220_78027380	0.46	Gm47829	predicted gene, 47829	645	0.57
chr1_179568743_179569078	0.46	Cnst	consortin, connexin sorting protein	22401	0.14
chr19_4579367_4579529	0.45	Pcx	pyruvate carboxylase	14898	0.12
chr3_59027427_59027590	0.45	Med12l	mediator complex subunit 12-like	20530	0.13
chr7_127892214_127892370	0.45	Prss53	protease, serine 53	1322	0.18
chr4_55249604_55249759	0.45	Gm12508	predicted gene 12508	5059	0.19
chr12_12812975_12813126	0.45	Platr19	pluripotency associated transcript 19	25065	0.16
chr11_50733265_50733435	0.45	Gm12200	predicted gene 12200	7806	0.16
chr10_61486909_61487060	0.45	Gm47595	predicted gene, 47595	9306	0.1
chr7_84167425_84167636	0.45	Gm22177	predicted gene, 22177	3035	0.2
chr1_119025916_119026110	0.44	Gli2	GLI-Kruppel family member GLI2	27326	0.18
chr10_61278018_61278535	0.44	Adamts14	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14	4838	0.17
chr10_84577349_84577529	0.44	Tcp11l2	t-complex 11 (mouse) like 2	542	0.69
chr19_46899287_46899584	0.44	Nt5c2	5'-nucleotidase, cytosolic II	10140	0.16
chr8_60631525_60631691	0.44	Gm34730	predicted gene, 34730	1123	0.39
chr8_119428106_119428304	0.43	Osgin1	oxidative stress induced growth inhibitor 1	5919	0.16
chr9_121912940_121913246	0.43	Cyp8b1	cytochrome P450, family 8, subfamily b, polypeptide 1	3212	0.11
chr17_50470603_50470784	0.43	Plcl2	phospholipase C-like 2	38710	0.2
chr9_65330615_65330808	0.43	Gm39363	predicted gene, 39363	1809	0.18
chr1_187314638_187314804	0.42	Gm38155	predicted gene, 38155	62748	0.1
chr5_143523600_143523751	0.42	Gm42502	predicted gene 42502	1985	0.22
chr2_29425513_29425708	0.42	Gm13402	predicted gene 13402	29151	0.13
chr2_144073598_144073761	0.42	Banf2os	barrier to autointegration factor 2, opposite strand	4873	0.2
chr5_66041014_66041178	0.42	Rbm47	RNA binding motif protein 47	13456	0.12
chr14_25377112_25377271	0.42	Gm26660	predicted gene, 26660	1444	0.44
chr8_123736984_123737175	0.42	Gm45781	predicted gene 45781	1937	0.14
chr8_11530930_11531091	0.42	Cars2	cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)	10624	0.12
chr17_29257751_29257902	0.42	Ppil1	peptidylprolyl isomerase (cyclophilin)-like 1	919	0.4
chr6_8347237_8347400	0.41	Gm16055	predicted gene 16055	16818	0.17
chr4_136210275_136210471	0.41	Asap3	ArfGAP with SH3 domain, ankyrin repeat and PH domain 3	4008	0.17
chr6_72234140_72234314	0.41	Atoh8	atonal bHLH transcription factor 8	310	0.88
chr19_47279393_47279569	0.41	Mir6995	microRNA 6995	5892	0.15
chr1_121336194_121336390	0.41	Insig2	insulin induced gene 2	3703	0.2
chr19_4746737_4746901	0.41	Sptbn2	spectrin beta, non-erythrocytic 2	5040	0.11
chr8_84910073_84910224	0.40	Dnase2a	deoxyribonuclease II alpha	313	0.72
chr3_108046974_108047188	0.40	Gstm4	glutathione S-transferase, mu 4	2187	0.13
chr3_132917460_132917629	0.40	Npnt	nephronectin	11185	0.16
chr10_80756563_80756714	0.40	Dot1l	DOT1-like, histone H3 methyltransferase (S. cerevisiae)	1175	0.27
chr4_115496100_115496304	0.40	Cyp4a14	cytochrome P450, family 4, subfamily a, polypeptide 14	60	0.96
chr11_78964690_78964876	0.39	Lgals9	lectin, galactose binding, soluble 9	5547	0.2
chr15_83535025_83535226	0.39	Bik	BCL2-interacting killer	1581	0.24
chr11_96827495_96827650	0.39	Nfe2l1	nuclear factor, erythroid derived 2,-like 1	147	0.92
chr2_32389034_32389190	0.38	Lcn2	lipocalin 2	860	0.38
chr2_32752327_32752485	0.38	Tor2a	torsin family 2, member A	4828	0.08
chr16_78377228_78377437	0.38	Btg3	BTG anti-proliferation factor 3	140	0.96
chr16_10981270_10981624	0.38	Litaf	LPS-induced TN factor	5868	0.12
chr1_121323063_121323261	0.38	Insig2	insulin induced gene 2	29	0.97
chr19_46090505_46090788	0.38	Nolc1	nucleolar and coiled-body phosphoprotein 1	14592	0.11
chr1_191803404_191803597	0.38	Gm20203	predicted gene, 20203	12186	0.13
chr11_109505108_109505274	0.38	Gm22378	predicted gene, 22378	5367	0.15
chr19_23071512_23071878	0.38	C330002G04Rik	RIKEN cDNA C330002G04 gene	4158	0.22
chr15_82184388_82184552	0.37	Gm49502	predicted gene, 49502	1046	0.32
chr2_144078197_144078361	0.37	Banf2os	barrier to autointegration factor 2, opposite strand	9473	0.18
chr12_82855785_82855951	0.37	1700085C21Rik	RIKEN cDNA 1700085C21 gene	83287	0.09
chr2_101903561_101903731	0.37	Commd9	COMM domain containing 9	17383	0.18
chr5_27997662_27998174	0.37	Gm4865	predicted gene 4865	3388	0.22
chr2_151925396_151925578	0.37	Angpt4	angiopoietin 4	14277	0.13
chr10_61327652_61327821	0.37	Pald1	phosphatase domain containing, paladin 1	14591	0.12
chr10_75030312_75030464	0.37	Rsph14	radial spoke head homolog 14 (Chlamydomonas)	2140	0.24
chr7_19864157_19864332	0.37	Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	2945	0.1
chr14_65722602_65722753	0.37	Scara5	scavenger receptor class A, member 5	46200	0.14
chr4_133028994_133029156	0.36	Ahdc1	AT hook, DNA binding motif, containing 1	10418	0.18
chr4_132946310_132946569	0.36	Gm24913	predicted gene, 24913	15122	0.13
chr17_34950661_34950834	0.36	Snord52	small nucleolar RNA, C/D box 52	270	0.54
chr2_68125158_68125473	0.36	B3galt1	UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1	7602	0.26
chr17_12421268_12421592	0.36	Plg	plasminogen	42771	0.11
chr2_167260546_167260697	0.36	Ptgis	prostaglandin I2 (prostacyclin) synthase	20017	0.13
chr7_68709416_68709593	0.35	Gm44692	predicted gene 44692	16963	0.21
chr3_85265951_85266104	0.35	1700036G14Rik	RIKEN cDNA 1700036G14 gene	51492	0.14
chr10_24096725_24097024	0.35	Taar8b	trace amine-associated receptor 8B	4580	0.1
chr18_34915325_34915481	0.35	Etf1	eukaryotic translation termination factor 1	16604	0.11
chr7_68305874_68306047	0.35	Fam169b	family with sequence similarity 169, member B	5847	0.14
chr13_24975507_24975663	0.35	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	12958	0.13
chr5_146901911_146902074	0.35	Gtf3a	general transcription factor III A	46665	0.09
chr6_145353488_145353649	0.34	Gm23498	predicted gene, 23498	13290	0.13
chr17_29459588_29459962	0.34	Gm36199	predicted gene, 36199	1269	0.31
chr19_53052494_53052645	0.34	Xpnpep1	X-prolyl aminopeptidase (aminopeptidase P) 1, soluble	12355	0.16
chr5_113989557_113989922	0.34	Ssh1	slingshot protein phosphatase 1	4	0.97
chr13_104641733_104641900	0.34	2610204G07Rik	RIKEN cDNA 2610204G07 gene	43115	0.19
chr2_69380923_69381087	0.34	Dhrs9	dehydrogenase/reductase (SDR family) member 9	560	0.78
chr16_92487174_92487325	0.34	Clic6	chloride intracellular channel 6	1513	0.32
chr3_84241254_84241427	0.33	Trim2	tripartite motif-containing 2	18029	0.22
chr5_105829261_105829440	0.33	Lrrc8d	leucine rich repeat containing 8D	4839	0.15
chr2_24800597_24800750	0.33	Ehmt1	euchromatic histone methyltransferase 1	5682	0.18
chr3_115789167_115789324	0.33	Gm9889	predicted gene 9889	74095	0.08
chr17_28280441_28280673	0.33	Ppard	peroxisome proliferator activator receptor delta	8438	0.11
chr12_21183267_21183628	0.33	AC156032.1		63876	0.08
chr9_75009043_75009194	0.33	Arpp19	cAMP-regulated phosphoprotein 19	28496	0.14
chr2_12197838_12198004	0.33	Itga8	integrin alpha 8	4609	0.27
chr10_75043100_75043251	0.33	Rab36	RAB36, member RAS oncogene family	4952	0.17
chr15_82241552_82241727	0.33	Cenpm	centromere protein M	2693	0.12
chr4_107920456_107920610	0.33	Cpt2	carnitine palmitoyltransferase 2	2914	0.18
chr15_54410361_54410512	0.33	Colec10	collectin sub-family member 10	338	0.9
chr4_46546296_46546462	0.33	Coro2a	coronin, actin binding protein 2A	3577	0.18
chr6_141875439_141875590	0.33	Gm30784	predicted gene, 30784	9156	0.21
chr12_104798236_104798545	0.32	Clmn	calmin	17519	0.19
chr19_58311318_58311494	0.32	Gm16277	predicted gene 16277	107267	0.07
chr17_28925057_28925224	0.32	Gm16191	predicted gene 16191	323	0.76
chr8_10939998_10940171	0.32	Gm44955	predicted gene 44955	7806	0.11
chr16_10953422_10953599	0.32	Gm26268	predicted gene, 26268	12214	0.11
chr5_119293252_119293427	0.32	n-R5s175	nuclear encoded rRNA 5S 175	3906	0.33
chr2_163166496_163166672	0.32	Gm14254	predicted gene 14254	10478	0.16
chr10_43440139_43440316	0.32	Gm3699	predicted gene 3699	16274	0.13
chr2_38607780_38607955	0.32	Gm13586	predicted gene 13586	14934	0.12
chr1_14795269_14795483	0.32	Gm37412	predicted gene, 37412	6731	0.2
chr12_102445552_102445736	0.32	Gm30198	predicted gene, 30198	1684	0.33
chr15_82458124_82458511	0.32	Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	2747	0.09
chr2_103865691_103865862	0.32	Gm13879	predicted gene 13879	22120	0.08
chr7_127841086_127841237	0.32	Stx4a	syntaxin 4A (placental)	603	0.48
chr4_55768439_55768659	0.32	Gm12506	predicted gene 12506	163400	0.03
chr10_95659852_95660024	0.32	Anapc15-ps	anaphase promoting complex C subunit 15, pseudogene	13451	0.12
chr9_62367194_62367386	0.32	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	346	0.89
chr15_36903404_36903565	0.32	Gm10384	predicted gene 10384	23668	0.13

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rxrb

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0046087	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2	0.6	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.4	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.1	0.4	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.1	0.3	GO:0097503	sialylation(GO:0097503)
0.1	0.2	GO:2000721	positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1	0.7	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.1	0.3	GO:0065001	specification of axis polarity(GO:0065001)
0.1	0.3	GO:0006528	asparagine metabolic process(GO:0006528)
0.1	0.3	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.1	0.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.2	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.1	0.2	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.1	0.2	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.1	0.2	GO:0009223	pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1	0.5	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.1	0.2	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.2	GO:0003415	chondrocyte hypertrophy(GO:0003415)
0.1	0.2	GO:0002125	maternal aggressive behavior(GO:0002125)
0.1	0.8	GO:0045603	positive regulation of endothelial cell differentiation(GO:0045603)
0.1	0.3	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.2	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	0.2	GO:0010535	positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.1	0.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.2	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1	0.4	GO:0071318	cellular response to ATP(GO:0071318)
0.1	0.2	GO:1902512	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.2	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0	0.1	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.2	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0	0.1	GO:1902566	regulation of eosinophil degranulation(GO:0043309) regulation of eosinophil activation(GO:1902566)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.2	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0040031	snRNA modification(GO:0040031)
0.0	0.2	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.2	GO:0032417	positive regulation of sodium:proton antiporter activity(GO:0032417)
0.0	0.0	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0	0.1	GO:0003166	bundle of His development(GO:0003166)
0.0	0.2	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0	0.2	GO:1904395	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.2	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:0071921	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.4	GO:0090051	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0	0.3	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.2	GO:0035331	negative regulation of hippo signaling(GO:0035331)
0.0	0.1	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.0	GO:0048382	mesendoderm development(GO:0048382)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.0	GO:0010692	regulation of alkaline phosphatase activity(GO:0010692)
0.0	0.1	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.1	GO:0002254	kinin cascade(GO:0002254)
0.0	0.2	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.2	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.1	GO:0080154	regulation of fertilization(GO:0080154)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.2	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.2	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.4	GO:0032926	negative regulation of activin receptor signaling pathway(GO:0032926)
0.0	0.1	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.1	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.1	GO:0071504	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.2	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.1	GO:0002086	diaphragm contraction(GO:0002086)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.1	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:1902606	regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0	0.2	GO:0072673	lamellipodium morphogenesis(GO:0072673)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:2000562	negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0	0.1	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.0	GO:0060128	corticotropin hormone secreting cell differentiation(GO:0060128)
0.0	0.1	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.1	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	0.2	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.1	GO:0090210	regulation of establishment of blood-brain barrier(GO:0090210)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.3	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.0	GO:0061626	pharyngeal arch artery morphogenesis(GO:0061626)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.1	GO:0070574	cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0031284	positive regulation of guanylate cyclase activity(GO:0031284)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.1	GO:0032261	purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0	0.0	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
0.0	0.1	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.1	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0	0.0	GO:1904673	regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072039) negative regulation of mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:0072040) mesenchymal cell apoptotic process involved in nephron morphogenesis(GO:1901145) regulation of somatic stem cell population maintenance(GO:1904672) negative regulation of somatic stem cell population maintenance(GO:1904673)
0.0	0.1	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.2	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.0	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.1	GO:0017183	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.2	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:0070100	negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.1	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.0	0.1	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0061511	centriole elongation(GO:0061511)
0.0	0.2	GO:0019511	peptidyl-proline hydroxylation(GO:0019511)
0.0	0.0	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0033184	positive regulation of histone ubiquitination(GO:0033184)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:0072053	renal inner medulla development(GO:0072053)
0.0	0.1	GO:1990928	response to amino acid starvation(GO:1990928)
0.0	0.0	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0	0.1	GO:0051970	negative regulation of transmission of nerve impulse(GO:0051970)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0	0.1	GO:0035509	negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0	0.0	GO:2000503	positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0021898	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882) commitment of multipotent stem cells to neuronal lineage in forebrain(GO:0021898)
0.0	0.0	GO:1900186	negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.1	GO:0072383	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.2	GO:0010566	regulation of ketone biosynthetic process(GO:0010566)
0.0	0.1	GO:0043134	hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.0	GO:2001185	regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0	0.1	GO:0009197	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.0	0.1	GO:0072282	metanephric nephron tubule morphogenesis(GO:0072282)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.2	GO:0002418	immune response to tumor cell(GO:0002418)
0.0	0.1	GO:0002934	desmosome organization(GO:0002934)
0.0	0.0	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.4	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.3	GO:0071711	basement membrane organization(GO:0071711)
0.0	0.1	GO:0006729	tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0	0.5	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:1903147	negative regulation of mitophagy(GO:1903147)
0.0	0.1	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.1	GO:0021860	pyramidal neuron development(GO:0021860)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.1	GO:1990441	negative regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990441)
0.0	0.1	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.1	GO:1900619	acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0	0.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.1	GO:0009115	xanthine catabolic process(GO:0009115) xanthine metabolic process(GO:0046110)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.2	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.0	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.0	GO:0046102	inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0	0.0	GO:0072402	response to cell cycle checkpoint signaling(GO:0072396) response to DNA integrity checkpoint signaling(GO:0072402) response to DNA damage checkpoint signaling(GO:0072423) response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:0006995	cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0	0.1	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.0	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.0	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.0	GO:0045588	positive regulation of gamma-delta T cell differentiation(GO:0045588) positive regulation of gamma-delta T cell activation(GO:0046645)
0.0	0.0	GO:0018208	peptidyl-proline modification(GO:0018208)
0.0	0.1	GO:0098814	spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.3	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.2	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:0043652	engulfment of apoptotic cell(GO:0043652)
0.0	0.0	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.1	GO:2000389	regulation of neutrophil extravasation(GO:2000389) positive regulation of neutrophil extravasation(GO:2000391)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.0	GO:0048293	isotype switching to IgE isotypes(GO:0048289) regulation of isotype switching to IgE isotypes(GO:0048293)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.2	GO:0015727	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.0	GO:0000101	sulfur amino acid transport(GO:0000101)
0.0	0.0	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.0	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.0	GO:0010916	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0009071	serine family amino acid catabolic process(GO:0009071)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.2	GO:0090005	negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0	0.1	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0042891	antibiotic transport(GO:0042891)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.2	GO:0007190	activation of adenylate cyclase activity(GO:0007190)
0.0	0.1	GO:0060670	branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0	0.1	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.2	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:1903546	protein localization to photoreceptor outer segment(GO:1903546)
0.0	0.0	GO:0061738	late endosomal microautophagy(GO:0061738)
0.0	0.1	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.1	GO:0006198	cAMP catabolic process(GO:0006198)
0.0	0.0	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.0	GO:0031052	programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052)
0.0	0.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.0	GO:0042908	xenobiotic transport(GO:0042908)
0.0	0.0	GO:2000354	regulation of ovarian follicle development(GO:2000354)
0.0	0.1	GO:0051601	exocyst localization(GO:0051601)
0.0	0.1	GO:0090129	positive regulation of synapse maturation(GO:0090129)
0.0	0.1	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.1	GO:0021702	cerebellar Purkinje cell differentiation(GO:0021702)
0.0	0.1	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:2000774	positive regulation of cellular senescence(GO:2000774)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0033121	regulation of purine nucleotide catabolic process(GO:0033121) regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.0	0.1	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.0	GO:0030035	microspike assembly(GO:0030035)
0.0	0.3	GO:0043252	sodium-independent organic anion transport(GO:0043252)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.0	GO:0014707	branchiomeric skeletal muscle development(GO:0014707)
0.0	0.1	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.0	GO:1903361	protein localization to basolateral plasma membrane(GO:1903361)
0.0	0.1	GO:0033574	response to testosterone(GO:0033574)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0010424	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.0	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.0	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.1	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.1	GO:0033008	positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0	0.1	GO:0007549	dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0	0.0	GO:0060368	regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060368)
0.0	0.0	GO:0090241	negative regulation of histone H4 acetylation(GO:0090241)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0035089	establishment of apical/basal cell polarity(GO:0035089)
0.0	0.0	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0046007	negative regulation of activated T cell proliferation(GO:0046007)
0.0	0.1	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.0	GO:0090309	positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0	0.1	GO:0060484	lung-associated mesenchyme development(GO:0060484)
0.0	0.0	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.0	GO:2000409	positive regulation of T cell extravasation(GO:2000409)
0.0	0.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.2	GO:0033962	cytoplasmic mRNA processing body assembly(GO:0033962)
0.0	0.0	GO:0051660	establishment of centrosome localization(GO:0051660)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.2	GO:0000322	storage vacuole(GO:0000322)
0.0	0.3	GO:0001739	sex chromatin(GO:0001739)
0.0	0.3	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.1	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.3	GO:0005577	fibrinogen complex(GO:0005577)
0.0	0.1	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0090661	box H/ACA telomerase RNP complex(GO:0090661)
0.0	0.4	GO:0000940	condensed chromosome outer kinetochore(GO:0000940)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.2	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.2	GO:0032591	dendritic spine membrane(GO:0032591)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.5	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.3	GO:0044215	other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0008278	cohesin complex(GO:0008278)
0.0	0.0	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)
0.0	0.0	GO:0031417	NatC complex(GO:0031417)
0.0	0.2	GO:0016580	Sin3 complex(GO:0016580)
0.0	0.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0	0.2	GO:0042612	MHC class I protein complex(GO:0042612)
0.0	0.2	GO:0038201	TOR complex(GO:0038201)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0036454	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.4	GO:0055038	recycling endosome membrane(GO:0055038)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.1	GO:0089717	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.3	GO:0033017	sarcoplasmic reticulum membrane(GO:0033017)
0.0	0.4	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.0	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.1	GO:0033010	paranodal junction(GO:0033010)
0.0	0.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.1	GO:0005828	kinetochore microtubule(GO:0005828)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0001891	phagocytic cup(GO:0001891)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0004126	cytidine deaminase activity(GO:0004126)
0.1	0.3	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.3	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.5	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1	0.2	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.3	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	0.3	GO:0005534	galactose binding(GO:0005534)
0.1	0.4	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.1	0.2	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1	0.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0031893	vasopressin receptor binding(GO:0031893)
0.1	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.3	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1	0.2	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.1	0.2	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.1	0.4	GO:0018634	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1	0.2	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.1	0.2	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1	0.2	GO:0016623	aldehyde oxidase activity(GO:0004031) oxidoreductase activity, acting on the aldehyde or oxo group of donors, oxygen as acceptor(GO:0016623)
0.0	0.2	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.3	GO:0018741	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.4	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.2	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.3	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.8	GO:0001530	lipopolysaccharide binding(GO:0001530)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.2	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.1	GO:0034513	box H/ACA snoRNA binding(GO:0034513)
0.0	0.1	GO:0050309	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.1	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0	0.3	GO:0016889	endodeoxyribonuclease activity, producing 3'-phosphomonoesters(GO:0016889)
0.0	0.1	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.2	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0003876	AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.1	GO:0051185	coenzyme transporter activity(GO:0051185)
0.0	0.6	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.0	0.1	GO:0034988	Fc-gamma receptor I complex binding(GO:0034988)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0030144	alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0	0.3	GO:0048185	activin binding(GO:0048185)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.3	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0048495	Roundabout binding(GO:0048495)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.3	GO:0051400	BH domain binding(GO:0051400)
0.0	0.4	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.0	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.2	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.0	GO:0015087	cobalt ion transmembrane transporter activity(GO:0015087)
0.0	0.3	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.1	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0004558	alpha-1,4-glucosidase activity(GO:0004558)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.3	GO:0005537	mannose binding(GO:0005537)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0008499	UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.1	GO:0046977	TAP binding(GO:0046977)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:0004955	prostaglandin receptor activity(GO:0004955)
0.0	0.2	GO:0016846	carbon-sulfur lyase activity(GO:0016846)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0004690	cyclic nucleotide-dependent protein kinase activity(GO:0004690)
0.0	0.0	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.0	GO:0001031	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0	0.0	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0031726	CCR1 chemokine receptor binding(GO:0031726)
0.0	0.1	GO:0034942	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.0	GO:0000182	rDNA binding(GO:0000182)
0.0	0.1	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.1	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.1	GO:0097027	ubiquitin-protein transferase activator activity(GO:0097027)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.0	GO:0035615	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.4	GO:0070888	E-box binding(GO:0070888)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.4	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0005166	neurotrophin p75 receptor binding(GO:0005166)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.0	GO:0098518	polynucleotide phosphatase activity(GO:0098518)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.0	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0031821	G-protein coupled serotonin receptor binding(GO:0031821)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0048156	tau protein binding(GO:0048156)
0.0	0.0	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.1	GO:0097157	pre-mRNA intronic binding(GO:0097157)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.0	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.1	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.0	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.0	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.0	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.0	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.0	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.3	GO:0032266	phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.0	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0	0.0	GO:0030375	thyroid hormone receptor coactivator activity(GO:0030375)
0.0	0.0	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0031078	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.2	GO:0022829	wide pore channel activity(GO:0022829)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.0	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.6	GO:0017022	myosin binding(GO:0017022)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	0.9	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.0	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	0.4	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.0	PID IGF1 PATHWAY	IGF1 pathway
0.0	0.4	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.0	0.4	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.1	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes
0.0	0.2	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	0.1	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.2	PID PRL SIGNALING EVENTS PATHWAY	Signaling events mediated by PRL
0.0	0.3	PID HDAC CLASSII PATHWAY	Signaling events mediated by HDAC Class II
0.0	0.5	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.1	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.1	PID ERBB1 DOWNSTREAM PATHWAY	ErbB1 downstream signaling
0.0	0.1	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID ECADHERIN NASCENT AJ PATHWAY	E-cadherin signaling in the nascent adherens junction
0.0	0.3	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	0.1	PID EPHA2 FWD PATHWAY	EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.4	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.4	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.5	REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT	Genes involved in Chylomicron-mediated lipid transport
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION	Genes involved in TRAF6 mediated IRF7 activation
0.0	0.2	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.4	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.2	REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY	Genes involved in Adenylate cyclase activating pathway
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.4	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.0	REACTOME MRNA CAPPING	Genes involved in mRNA Capping
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.0	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.1	REACTOME THE NLRP3 INFLAMMASOME	Genes involved in The NLRP3 inflammasome
0.0	0.0	REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE	Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.0	0.2	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.0	REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21	Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.1	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A	Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.0	0.0	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG

Results for Rxrb

Z-value: 1.49

Motif logo

Transcription factors associated with Rxrb

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Rxrb motif across conditions

Conditions sorted by the z-value of the Rxrb motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Rxrb

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: