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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Scrt1

Z-value: 0.89

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Transcription factors associated with Scrt1

Gene Symbol Gene ID Gene Info
Scrt1
ENSMUSG00000048385.8 Scrt1

Activity of the Scrt1 motif across conditions

Conditions sorted by the z-value of the Scrt1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr13_34073715_34073878 0.48 Tubb2a
 tubulin, beta 2A class IIA
 4211
 0.12
chr6_121890040_121890777 0.39 Mug1
 murinoglobulin 1
 4831
 0.21
chr2_71633995_71634167 0.38 Platr26
 pluripotency associated transcript 26
 85336
 0.06
chr3_83005590_83005767 0.36 Fgg
 fibrinogen gamma chain
 2046
 0.24
chr11_49088297_49088883 0.36 Gm12188
 predicted gene 12188
 47
 0.79
chr11_116108287_116108624 0.35 Trim47
 tripartite motif-containing 47
 336
 0.77
chr18_46718177_46718358 0.34 Cdo1
 cysteine dioxygenase 1, cytosolic
 9762
 0.13
chr5_8985691_8985842 0.32 Crot
 carnitine O-octanoyltransferase
 3622
 0.15
chr1_183297724_183297875 0.31 Aida
 axin interactor, dorsalization associated
 229
 0.74
chr5_89033271_89033463 0.31 Slc4a4
 solute carrier family 4 (anion exchanger), member 4
 5275
 0.32
chr17_28272441_28272592 0.31 Ppard
 peroxisome proliferator activator receptor delta
 397
 0.76
chr3_135582591_135582742 0.30 Nfkb1
 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
 11775
 0.16
chr11_102217522_102217681 0.30 Hdac5
 histone deacetylase 5
 1327
 0.26
chr12_109988471_109988667 0.29 Gm34667
 predicted gene, 34667
 35304
 0.09
chr13_55563371_55563565 0.29 Fam193b
 family with sequence similarity 193, member B
 4560
 0.1
chr11_82573919_82574081 0.28 Gm24612
 predicted gene, 24612
 22179
 0.19
chr6_57417438_57417602 0.27 Vmn1r20
 vomeronasal 1 receptor 20
 11410
 0.12
chr18_20936854_20937178 0.27 Rnf125
 ring finger protein 125
 7609
 0.22
chr12_21141829_21142079 0.27 Asap2
 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
 30000
 0.17
chr9_102403327_102403577 0.26 Gm22894
 predicted gene, 22894
 30334
 0.14
chr11_112374092_112374250 0.26 Gm11680
 predicted gene 11680
 266733
 0.02
chr7_30361694_30362080 0.26 Lrfn3
 leucine rich repeat and fibronectin type III domain containing 3
 885
 0.31
chr7_24595302_24595547 0.26 Zfp575
 zinc finger protein 575
 7783
 0.08
chr18_20114615_20114773 0.26 Dsc1
 desmocollin 1
 37
 0.98
chr1_46345449_46345605 0.26 Dnah7b
 dynein, axonemal, heavy chain 7B
 11093
 0.21
chr15_80680833_80681008 0.25 Fam83f
 family with sequence similarity 83, member F
 9073
 0.13
chr2_118554450_118554815 0.25 Bmf
 BCL2 modifying factor
 4945
 0.18
chr19_36675015_36675190 0.24 Hectd2os
 Hectd2, opposite strand
 14171
 0.22
chr3_133765600_133766533 0.24 Gm6135
 prediticted gene 6135
 25438
 0.2
chr4_105225226_105225391 0.24 Plpp3
 phospholipid phosphatase 3
 67961
 0.13
chr15_77831173_77831327 0.23 Gm22107
 predicted gene, 22107
 9506
 0.15
chr10_19062073_19062383 0.23 1700124M09Rik
 RIKEN cDNA 1700124M09 gene
 24950
 0.14
chr10_24087275_24087474 0.23 Taar8b
 trace amine-associated receptor 8B
 4920
 0.1
chr11_80429840_80430182 0.23 Psmd11
 proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
 124
 0.96
chr1_184873376_184873577 0.23 C130074G19Rik
 RIKEN cDNA C130074G19 gene
 9742
 0.16
chr16_91786325_91786478 0.23 Itsn1
 intersectin 1 (SH3 domain protein 1A)
 2296
 0.28
chr2_103589515_103589686 0.23 Abtb2
 ankyrin repeat and BTB (POZ) domain containing 2
 23290
 0.18
chr6_90716699_90716865 0.23 Iqsec1
 IQ motif and Sec7 domain 1
 253
 0.91
chr10_8086797_8087175 0.23 Gm48614
 predicted gene, 48614
 65694
 0.11
chr5_33934831_33935145 0.22 Nelfa
 negative elongation factor complex member A, Whsc2
 1262
 0.31
chr6_72572233_72572384 0.22 Capg
 capping protein (actin filament), gelsolin-like
 16329
 0.09
chr6_135133072_135133223 0.22 Gm29803
 predicted gene, 29803
 1305
 0.32
chr2_164158645_164158808 0.22 n-R5s207
 nuclear encoded rRNA 5S 207
 1205
 0.29
chr2_151943059_151943241 0.22 Gm14154
 predicted gene 14154
 7491
 0.14
chr4_144913207_144913382 0.22 Dhrs3
 dehydrogenase/reductase (SDR family) member 3
 5585
 0.23
chr1_72182919_72183124 0.22 Mreg
 melanoregulin
 29286
 0.12
chr17_31303465_31303616 0.21 Slc37a1
 solute carrier family 37 (glycerol-3-phosphate transporter), member 1
 2003
 0.24
chr6_72604832_72604993 0.21 Retsat
 retinol saturase (all trans retinol 13,14 reductase)
 539
 0.39
chr9_48675944_48676095 0.21 Nnmt
 nicotinamide N-methyltransferase
 70866
 0.11
chr9_64795430_64795739 0.21 Dennd4a
 DENN/MADD domain containing 4A
 15756
 0.19
chr11_7203968_7204174 0.21 Igfbp1
 insulin-like growth factor binding protein 1
 6289
 0.18
chr18_21220186_21220337 0.21 Garem1
 GRB2 associated regulator of MAPK1 subtype 1
 79862
 0.08
chr1_84059698_84059849 0.21 Pid1
 phosphotyrosine interaction domain containing 1
 6520
 0.27
chr8_35417462_35417628 0.21 Gm45301
 predicted gene 45301
 8039
 0.17
chr10_59466713_59466931 0.21 Mcu
 mitochondrial calcium uniporter
 8662
 0.2
chr15_74956771_74956940 0.20 Ly6e
 lymphocyte antigen 6 complex, locus E
 300
 0.78
chr10_61236047_61236201 0.20 Adamts14
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 14
 37118
 0.12
chr6_54041419_54041593 0.20 Chn2
 chimerin 2
 1420
 0.45
chr11_101466397_101466548 0.20 Vat1
 vesicle amine transport 1
 242
 0.75
chr11_112810941_112811143 0.20 Gm11681
 predicted gene 11681
 12034
 0.18
chr3_91483300_91483476 0.20 S100a7l2
 S100 calcium binding protein A7 like 2
 392585
 0.01
chr11_86971141_86971293 0.20 Ypel2
 yippee like 2
 807
 0.62
chr4_144924031_144924237 0.20 Dhrs3
 dehydrogenase/reductase (SDR family) member 3
 5255
 0.22
chr11_101927534_101927685 0.19 Rpl27-ps2
 ribosomal protein L27, pseudogene 2
 11892
 0.1
chr4_144895225_144895561 0.19 Dhrs3
 dehydrogenase/reductase (SDR family) member 3
 2174
 0.34
chr1_74245666_74245817 0.19 Arpc2
 actin related protein 2/3 complex, subunit 2
 9191
 0.09
chr18_21373812_21373963 0.19 Gm22886
 predicted gene, 22886
 7044
 0.2
chr12_113221349_113221516 0.19 Gm25622
 predicted gene, 25622
 7283
 0.14
chr8_40996387_40996577 0.18 Mtus1
 mitochondrial tumor suppressor 1
 3723
 0.2
chr12_8004519_8005312 0.18 Apob
 apolipoprotein B
 7444
 0.24
chr14_22817406_22817579 0.18 Gm7473
 predicted gene 7473
 42248
 0.2
chr9_23030248_23030409 0.18 Bmper
 BMP-binding endothelial regulator
 192748
 0.03
chr13_17719442_17719753 0.18 Gm48621
 predicted gene, 48621
 9733
 0.11
chr19_30093012_30093163 0.18 Uhrf2
 ubiquitin-like, containing PHD and RING finger domains 2
 1126
 0.54
chr6_5233850_5234020 0.18 Gm44250
 predicted gene, 44250
 13449
 0.16
chr2_103500304_103500503 0.18 Cat
 catalase
 15243
 0.17
chr16_86430347_86430530 0.18 Gm32357
 predicted gene, 32357
 194267
 0.03
chr12_40483542_40483866 0.18 Dock4
 dedicator of cytokinesis 4
 37368
 0.17
chr4_126091770_126091957 0.18 Oscp1
 organic solute carrier partner 1
 4184
 0.13
chr2_156175837_156176038 0.18 Rbm39
 RNA binding motif protein 39
 1446
 0.28
chr12_84203864_84204015 0.18 Gm31513
 predicted gene, 31513
 7970
 0.11
chr10_78324948_78325156 0.18 Agpat3
 1-acylglycerol-3-phosphate O-acyltransferase 3
 4362
 0.1
chr12_50524263_50524422 0.17 Prkd1
 protein kinase D1
 124756
 0.06
chr5_52982111_52982447 0.17 Gm30301
 predicted gene, 30301
 242
 0.91
chr5_28056784_28057184 0.17 Gm26608
 predicted gene, 26608
 1525
 0.35
chr8_120490974_120491151 0.17 Gse1
 genetic suppressor element 1, coiled-coil protein
 2615
 0.22
chr4_117332720_117332922 0.17 Rnf220
 ring finger protein 220
 32793
 0.11
chr15_80645592_80645756 0.17 Mir6957
 microRNA 6957
 399
 0.79
chr2_24479227_24479538 0.17 Pax8
 paired box 8
 3783
 0.16
chr8_70719996_70720390 0.17 Gm3336
 predicted gene 3336
 1650
 0.16
chr6_105760602_105760775 0.17 Cntn4
 contactin 4
 82913
 0.1
chr4_65974196_65974358 0.17 Trim32
 tripartite motif-containing 32
 369028
 0.01
chr12_31944779_31944949 0.17 Hbp1
 high mobility group box transcription factor 1
 4457
 0.22
chr18_37953146_37953310 0.17 Hdac3
 histone deacetylase 3
 1690
 0.17
chr16_87512452_87512619 0.17 Gm24891
 predicted gene, 24891
 15630
 0.12
chr9_42293744_42293907 0.17 Gm36435
 predicted gene, 36435
 13947
 0.15
chr4_127077236_127077665 0.17 Zmym6
 zinc finger, MYM-type 6
 8
 0.96
chr17_29394463_29394614 0.17 Fgd2
 FYVE, RhoGEF and PH domain containing 2
 18037
 0.11
chr12_108359338_108359496 0.17 Cyp46a1
 cytochrome P450, family 46, subfamily a, polypeptide 1
 7193
 0.17
chr15_36476020_36476181 0.16 Ankrd46
 ankyrin repeat domain 46
 20615
 0.13
chr4_58148098_58148270 0.16 Svep1
 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
 58412
 0.14
chr8_127946458_127946625 0.16 Mir21c
 microRNA 21c
 331684
 0.01
chr1_160895233_160895410 0.16 Gm6177
 predicted gene 6177
 2201
 0.15
chr2_156311618_156311968 0.16 Cnbd2
 cyclic nucleotide binding domain containing 2
 506
 0.53
chr12_8003138_8004354 0.16 Apob
 apolipoprotein B
 8613
 0.24
chr19_3877298_3877449 0.16 Chka
 choline kinase alpha
 1968
 0.16
chr8_34941364_34941583 0.16 Tnks
 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
 22705
 0.16
chr5_130139764_130139934 0.16 Kctd7
 potassium channel tetramerisation domain containing 7
 5012
 0.13
chr11_22276015_22276166 0.16 Ehbp1
 EH domain binding protein 1
 9748
 0.28
chr5_8968601_8968752 0.16 Gm15610
 predicted gene 15610
 3272
 0.16
chr8_22404559_22404725 0.15 Gm45452
 predicted gene 45452
 1890
 0.18
chr19_46131357_46131554 0.15 Elovl3
 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3
 442
 0.73
chr8_33801179_33801330 0.15 Rbpms
 RNA binding protein gene with multiple splicing
 4040
 0.18
chr7_78903289_78903499 0.15 Aen
 apoptosis enhancing nuclease
 815
 0.5
chr11_102208183_102208370 0.15 Hdac5
 histone deacetylase 5
 7460
 0.09
chr1_180177544_180177695 0.15 Coq8a
 coenzyme Q8A
 1012
 0.47
chr6_55001492_55001666 0.15 Ggct
 gamma-glutamyl cyclotransferase
 8629
 0.17
chr4_154159940_154160245 0.15 Tprgl
 transformation related protein 63 regulated like
 74
 0.95
chr1_182500136_182500458 0.15 Gm37069
 predicted gene, 37069
 6141
 0.15
chr13_93630762_93631092 0.15 Gm15622
 predicted gene 15622
 5545
 0.17
chr2_72907906_72908071 0.15 Sp3
 trans-acting transcription factor 3
 33096
 0.14
chr15_102171688_102171839 0.15 Csad
 cysteine sulfinic acid decarboxylase
 7256
 0.1
chr16_4701536_4701728 0.15 Nmral1
 NmrA-like family domain containing 1
 17456
 0.1
chr12_61927306_61927476 0.15 Gm24750
 predicted gene, 24750
 6817
 0.22
chr4_141751428_141751718 0.15 Agmat
 agmatine ureohydrolase (agmatinase)
 4901
 0.14
chr15_101191263_101191414 0.15 Mir6962
 microRNA 6962
 2531
 0.16
chr4_133130667_133130841 0.15 Wasf2
 WAS protein family, member 2
 125
 0.96
chr10_42987828_42987979 0.15 Gm47815
 predicted gene, 47815
 47090
 0.12
chr11_105281077_105281256 0.15 Mrc2
 mannose receptor, C type 2
 11477
 0.19
chrX_86250773_86250944 0.15 Mageb4
 melanoma antigen, family B, 4
 5361
 0.18
chr13_92740047_92740198 0.15 Gm5199
 predicted gene 5199
 20760
 0.17
chr5_114599320_114599476 0.15 Trpv4
 transient receptor potential cation channel, subfamily V, member 4
 31240
 0.12
chr3_96736661_96736837 0.15 Rnf115
 ring finger protein 115
 8910
 0.08
chr4_32507009_32507324 0.15 Bach2
 BTB and CNC homology, basic leucine zipper transcription factor 2
 5661
 0.25
chr14_46061047_46061231 0.15 Gm37257
 predicted gene, 37257
 10
 0.98
chr15_66284513_66284672 0.15 Kcnq3
 potassium voltage-gated channel, subfamily Q, member 3
 1459
 0.38
chr6_37871246_37871403 0.15 Trim24
 tripartite motif-containing 24
 513
 0.8
chr5_122303802_122304107 0.15 Gm15842
 predicted gene 15842
 1532
 0.26
chr15_80081005_80081156 0.14 Rpl3
 ribosomal protein L3
 599
 0.39
chr3_157918436_157918587 0.14 Cth
 cystathionase (cystathionine gamma-lyase)
 6540
 0.14
chr19_4878250_4878444 0.14 Zdhhc24
 zinc finger, DHHC domain containing 24
 321
 0.53
chr4_61590678_61590958 0.14 Mup17
 major urinary protein 17
 5053
 0.19
chr7_65370516_65370694 0.14 Tjp1
 tight junction protein 1
 410
 0.84
chr1_36546473_36546624 0.14 Ankrd39
 ankyrin repeat domain 39
 671
 0.47
chr15_75994590_75994817 0.14 Mapk15
 mitogen-activated protein kinase 15
 934
 0.32
chr14_118124640_118124836 0.14 Tgds
 TDP-glucose 4,6-dehydratase
 8006
 0.18
chr11_86952607_86952758 0.14 Ypel2
 yippee like 2
 19342
 0.18
chr6_121561006_121561170 0.14 Gm43934
 predicted gene, 43934
 887
 0.55
chr6_51270618_51270787 0.14 Mir148a
 microRNA 148a
 792
 0.68
chr10_74935143_74935297 0.14 Gnaz
 guanine nucleotide binding protein, alpha z subunit
 31957
 0.17
chr13_34725685_34725960 0.14 Gm47151
 predicted gene, 47151
 5071
 0.13
chr17_31788157_31788318 0.14 Gm49999
 predicted gene, 49999
 1267
 0.43
chr11_18900383_18900558 0.14 2900018N21Rik
 RIKEN cDNA 2900018N21 gene
 10630
 0.16
chr19_32534401_32535184 0.14 Gm36419
 predicted gene, 36419
 8556
 0.18
chr11_72281229_72281388 0.14 n-R5s70
 nuclear encoded rRNA 5S 70
 292
 0.83
chr18_36713491_36713783 0.14 Cd14
 CD14 antigen
 13101
 0.07
chr6_124453188_124453388 0.14 Clstn3
 calsyntenin 3
 3116
 0.14
chr9_59470341_59470523 0.14 Rps11-ps1
 ribosomal protein S11, pseudogene 1
 1801
 0.31
chr1_72837567_72837745 0.14 Igfbp2
 insulin-like growth factor binding protein 2
 11043
 0.21
chr2_164562758_164562924 0.14 Wfdc2
 WAP four-disulfide core domain 2
 127
 0.9
chr8_120619240_120619416 0.14 1190005I06Rik
 RIKEN cDNA 1190005I06 gene
 15035
 0.09
chr13_98693378_98693698 0.14 Tmem171
 transmembrane protein 171
 1230
 0.37
chr17_5840748_5840949 0.14 Snx9
 sorting nexin 9
 481
 0.74
chr12_81595637_81595788 0.13 Med6
 mediator complex subunit 6
 704
 0.53
chr5_64542110_64542274 0.13 Gm43836
 predicted gene 43836
 15991
 0.12
chr12_83474032_83474213 0.13 Dpf3
 D4, zinc and double PHD fingers, family 3
 13586
 0.18
chr4_55242971_55243122 0.13 Gm12508
 predicted gene 12508
 11694
 0.17
chr4_119117332_119117542 0.13 Slc2a1
 solute carrier family 2 (facilitated glucose transporter), member 1
 8523
 0.1
chr12_111894295_111894473 0.13 Ppp1r13b
 protein phosphatase 1, regulatory subunit 13B
 13235
 0.12
chr6_17319461_17319624 0.13 Cav1
 caveolin 1, caveolae protein
 11819
 0.18
chr11_97958258_97958415 0.13 Gm11633
 predicted gene 11633
 10456
 0.1
chr12_104355745_104355928 0.13 Serpina3l-ps
 serine (or cysteine) peptidase inhibitor, clade A, member 3L, pseudogene
 2167
 0.21
chr1_74190938_74191089 0.13 Cxcr1
 chemokine (C-X-C motif) receptor 1
 2222
 0.19
chr4_11089211_11089550 0.13 Ndufaf6
 NADH:ubiquinone oxidoreductase complex assembly factor 6
 13175
 0.14
chr13_42341987_42342149 0.13 Gm47118
 predicted gene, 47118
 37077
 0.17
chr7_28801073_28801224 0.13 Rinl
 Ras and Rab interactor-like
 3250
 0.1
chr5_134853069_134853266 0.13 Tmem270
 transmembrane protein 270
 53566
 0.07
chr12_104798010_104798169 0.13 Clmn
 calmin
 17218
 0.19
chr1_105891390_105891564 0.13 Gm37779
 predicted gene, 37779
 465
 0.82
chr4_120666699_120666867 0.13 Cited4
 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
 211
 0.92
chr5_123791025_123791189 0.13 Kntc1
 kinetochore associated 1
 3895
 0.18
chr5_76306348_76306506 0.13 Gm7467
 predicted gene 7467
 1551
 0.23
chr4_60416791_60417110 0.13 Mup9
 major urinary protein 9
 3634
 0.18
chr1_111864068_111864581 0.13 Dsel
 dermatan sulfate epimerase-like
 444
 0.83
chr12_100989931_100990090 0.13 Gm36756
 predicted gene, 36756
 2962
 0.17
chr17_63497841_63498445 0.13 Fbxl17
 F-box and leucine-rich repeat protein 17
 1874
 0.43
chr8_107483340_107483510 0.13 Wwp2
 WW domain containing E3 ubiquitin protein ligase 2
 93
 0.97
chr5_37874933_37875104 0.13 Gm20052
 predicted gene, 20052
 18754
 0.19
chr7_141569233_141569384 0.13 Ap2a2
 adaptor-related protein complex 2, alpha 2 subunit
 6778
 0.12
chr14_114418353_114418542 0.13 Gm19829
 predicted gene, 19829
 107644
 0.08
chr13_48956580_48956936 0.13 Fam120a
 family with sequence similarity 120, member A
 11259
 0.23
chr16_22958475_22958991 0.13 Hrg
 histidine-rich glycoprotein
 7633
 0.12
chr11_72243451_72243602 0.13 1700051A21Rik
 RIKEN cDNA 1700051A21 gene
 22895
 0.09
chr14_68361550_68361701 0.13 Gm31227
 predicted gene, 31227
 100006
 0.07
chr9_57758758_57758995 0.13 Clk3
 CDC-like kinase 3
 3555
 0.17
chr8_115757553_115757722 0.13 Maf
 avian musculoaponeurotic fibrosarcoma oncogene homolog
 49843
 0.16
chr3_142191728_142191879 0.13 Gm6059
 predicted gene 6059
 7052
 0.23
chr17_26610962_26611350 0.13 Ergic1
 endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
 2294
 0.2
chr6_54850083_54850243 0.12 Znrf2
 zinc and ring finger 2
 32715
 0.16
chr9_37211963_37212270 0.12 Tmem218
 transmembrane protein 218
 3893
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

StringDB image

First level regulatory network of Scrt1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.2 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.2 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0010535 positive regulation of activation of JAK2 kinase activity(GO:0010535)
0.0 0.1 GO:0042524 negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0 0.2 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:2000850 negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0 0.1 GO:0060988 lipid tube assembly(GO:0060988)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0071476 cellular hypotonic response(GO:0071476)
0.0 0.1 GO:0006533 aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0006057 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.0 0.2 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:1900211 mesenchymal cell apoptotic process involved in metanephros development(GO:1900200) regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900211) negative regulation of mesenchymal cell apoptotic process involved in metanephros development(GO:1900212)
0.0 0.1 GO:0072378 blood coagulation, fibrin clot formation(GO:0072378)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.1 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:2000392 regulation of lamellipodium morphogenesis(GO:2000392)
0.0 0.0 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.1 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.0 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
0.0 0.1 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.1 GO:0048242 epinephrine secretion(GO:0048242)
0.0 0.1 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0 0.0 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.0 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.0 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:2000065 negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0 0.0 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.0 GO:0021882 regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0 0.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:0007418 ventral midline development(GO:0007418)
0.0 0.0 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.0 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.1 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.0 0.0 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.0 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.0 GO:0072061 inner medullary collecting duct development(GO:0072061)
0.0 0.0 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.0 GO:0002904 positive regulation of B cell apoptotic process(GO:0002904)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.0 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.0 GO:0000019 regulation of mitotic recombination(GO:0000019)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.0 GO:0008355 olfactory learning(GO:0008355)
0.0 0.1 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.0 GO:0009698 phenylpropanoid metabolic process(GO:0009698) phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.0 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.0 0.1 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0035189 Rb-E2F complex(GO:0035189)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0031264 death-inducing signaling complex(GO:0031264)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:1990696 USH2 complex(GO:1990696)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.3 GO:0022624 proteasome accessory complex(GO:0022624)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.0 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0070110 ciliary neurotrophic factor receptor complex(GO:0070110)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.1 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.0 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.0 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.1 GO:0005828 kinetochore microtubule(GO:0005828)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.1 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.2 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0018637 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.2 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.0 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0 0.1 GO:0003933 GTP cyclohydrolase activity(GO:0003933)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.0 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.1 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.0 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0071209 U7 snRNA binding(GO:0071209)
0.0 0.0 GO:0009374 biotin binding(GO:0009374)
0.0 0.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0 0.0 GO:0004813 alanine-tRNA ligase activity(GO:0004813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.0 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation