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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Smad2

Z-value: 2.38

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Transcription factors associated with Smad2

Gene Symbol	Gene ID	Gene Info
Smad2 Ensembl NCBI MGI UniProt	ENSMUSG00000024563.9	SMAD family member 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr18_76245451_76245606	Smad2	3354	0.228673	0.91	1.2e-02	Click!
chr18_76245200_76245359	Smad2	3105	0.236763	0.90	1.3e-02	Click!
chr18_76266839_76267012	Smad2	4433	0.226781	-0.88	2.2e-02	Click!
chr18_76245644_76245795	Smad2	3545	0.223504	0.87	2.3e-02	Click!
chr18_76264030_76264209	Smad2	1627	0.388217	-0.86	2.9e-02	Click!

Activity of the Smad2 motif across conditions

Conditions sorted by the z-value of the Smad2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_81376267_81376581	1.83	Gm50044	predicted gene, 50044	5591	0.28
chr6_72125643_72125794	1.80	4933431G14Rik	RIKEN cDNA 4933431G14 gene	2521	0.19
chr3_129584585_129584736	1.76	Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	32280	0.14
chr5_102643765_102644161	1.62	Arhgap24	Rho GTPase activating protein 24	81010	0.11
chr11_72609282_72609433	1.62	Ube2g1	ubiquitin-conjugating enzyme E2G 1	2038	0.25
chr4_131722484_131723038	1.47	Gm16080	predicted gene 16080	12253	0.19
chr6_135182328_135182527	1.29	Gm19434	predicted gene, 19434	6053	0.12
chr4_137795816_137796289	1.14	Alpl	alkaline phosphatase, liver/bone/kidney	178	0.96
chr13_98716100_98716291	1.09	Gm9465	predicted gene 9465	315	0.84
chr15_31250599_31250840	1.08	Dap	death-associated protein	17617	0.15
chr11_63851634_63851785	1.05	Hmgb1-ps3	high mobility group box 1, pseudogene 3	4891	0.25
chr1_21264707_21265188	0.99	Gm28836	predicted gene 28836	6646	0.11
chr18_61880354_61880505	0.97	Ablim3	actin binding LIM protein family, member 3	31394	0.16
chr15_62044174_62044346	0.95	Pvt1	Pvt1 oncogene	5003	0.28
chr13_13591194_13591382	0.95	Lyst	lysosomal trafficking regulator	879	0.64
chr9_61596903_61597054	0.93	Gm34424	predicted gene, 34424	63563	0.12
chr1_51750897_51751126	0.91	Gm28055	predicted gene 28055	4068	0.24
chr7_98401453_98401769	0.91	Gm44507	predicted gene 44507	14013	0.13
chr7_72216332_72216639	0.89	Mctp2	multiple C2 domains, transmembrane 2	12875	0.25
chr11_120810230_120810550	0.89	Fasn	fatty acid synthase	689	0.48
chr15_100660633_100660784	0.88	Bin2	bridging integrator 2	8797	0.09
chr12_84009300_84009480	0.87	Acot1	acyl-CoA thioesterase 1	100	0.93
chr3_90081344_90081692	0.87	Tpm3	tropomyosin 3, gamma	1076	0.29
chr19_24981612_24981763	0.85	Dock8	dedicator of cytokinesis 8	17847	0.15
chr17_81385422_81385814	0.85	Gm50044	predicted gene, 50044	14785	0.24
chr3_28717597_28717748	0.85	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	3845	0.2
chr7_24928137_24928288	0.85	Arhgef1	Rho guanine nucleotide exchange factor (GEF) 1	4849	0.1
chr9_24502048_24502199	0.81	Dpy19l1	dpy-19-like 1 (C. elegans)	1017	0.45
chr16_37535255_37535498	0.80	Gtf2e1	general transcription factor II E, polypeptide 1 (alpha subunit)	4400	0.17
chr15_101176132_101176283	0.79	Acvr1b	activin A receptor, type 1B	2140	0.19
chr10_87051307_87051578	0.78	1700113H08Rik	RIKEN cDNA 1700113H08 gene	6603	0.2
chr11_95387473_95387807	0.77	Slc35b1	solute carrier family 35, member B1	2345	0.19
chr2_72157539_72157839	0.77	Rapgef4os1	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 1	8893	0.2
chr10_82787893_82788044	0.77	Gm47561	predicted gene, 47561	16647	0.11
chr13_8987518_8987686	0.76	Gtpbp4	GTP binding protein 4	1511	0.23
chr3_159495094_159495249	0.76	Depdc1a	DEP domain containing 1a	262	0.93
chr15_31540515_31540666	0.76	Marchf6	membrane associated ring-CH-type finger 6	9537	0.13
chr1_91103487_91103647	0.76	Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	7647	0.19
chr5_53994229_53994741	0.75	Stim2	stromal interaction molecule 2	4014	0.29
chr1_151326184_151326719	0.74	Gm10138	predicted gene 10138	17631	0.14
chr9_48984872_48985421	0.73	Usp28	ubiquitin specific peptidase 28	229	0.92
chr3_94703351_94703645	0.72	Selenbp2	selenium binding protein 2	9839	0.11
chr8_34157897_34158198	0.71	Saraf	store-operated calcium entry-associated regulatory factor	434	0.71
chr14_64154379_64154546	0.70	9630015K15Rik	RIKEN cDNA 9630015K15 gene	38148	0.11
chr1_21267061_21267212	0.69	Gm28836	predicted gene 28836	4457	0.12
chr6_90594524_90595009	0.68	Gm15756	predicted gene 15756	5182	0.15
chr1_92902865_92903036	0.68	Ankmy1	ankyrin repeat and MYND domain containing 1	44	0.95
chr4_139601582_139602248	0.67	Gm21969	predicted gene 21969	1271	0.37
chr16_92637112_92637263	0.67	Gm26626	predicted gene, 26626	24373	0.19
chr15_59633296_59633447	0.67	Gm36677	predicted gene, 36677	14781	0.19
chr8_18713888_18714465	0.66	Angpt2	angiopoietin 2	14629	0.17
chr4_63155478_63155798	0.66	Ambp	alpha 1 microglobulin/bikunin precursor	839	0.59
chr2_75715387_75715582	0.65	E030042O20Rik	RIKEN cDNA E030042O20 gene	10714	0.12
chr9_48717198_48717480	0.65	Nnmt	nicotinamide N-methyltransferase	112186	0.06
chr15_81342867_81343141	0.64	Slc25a17	solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17	1153	0.42
chr19_58911487_58911665	0.63	Mir3086	microRNA 3086	183	0.95
chr9_106788095_106788832	0.63	Rad54l2	RAD54 like 2 (S. cerevisiae)	713	0.62
chr14_29976665_29976837	0.62	Actr8	ARP8 actin-related protein 8	1586	0.25
chr15_73186721_73186872	0.62	Ago2	argonaute RISC catalytic subunit 2	1861	0.34
chr9_119148405_119148556	0.62	Acaa1b	acetyl-Coenzyme A acyltransferase 1B	1583	0.25
chr15_57714741_57714900	0.62	Gm16006	predicted gene 16006	5893	0.21
chr1_74029308_74029738	0.61	Tns1	tensin 1	7610	0.23
chr19_58373764_58373922	0.61	Gfra1	glial cell line derived neurotrophic factor family receptor alpha 1	80623	0.09
chr3_41587384_41587535	0.61	Jade1	jade family PHD finger 1	4214	0.19
chr12_83591717_83592019	0.61	Zfyve1	zinc finger, FYVE domain containing 1	3819	0.18
chr19_47472562_47472746	0.61	Sh3pxd2a	SH3 and PX domains 2A	8253	0.18
chr9_104107214_104107444	0.61	Gm46999	predicted gene, 46999	2893	0.14
chr1_21298200_21298351	0.61	Gm4956	predicted gene 4956	28	0.96
chr2_130894667_130894834	0.60	A730017L22Rik	RIKEN cDNA A730017L22 gene	11606	0.13
chr14_14067010_14067161	0.60	Atxn7	ataxin 7	20384	0.17
chr15_42296635_42296795	0.60	Gm49452	predicted gene, 49452	23631	0.17
chr1_60658861_60659059	0.59	Gm11577	predicted gene 11577	41912	0.09
chr16_91826705_91826897	0.59	Itsn1	intersectin 1 (SH3 domain protein 1A)	736	0.66
chr14_118951752_118951943	0.59	Dnajc3	DnaJ heat shock protein family (Hsp40) member C3	13871	0.16
chr6_108253490_108253690	0.58	Itpr1	inositol 1,4,5-trisphosphate receptor 1	632	0.8
chr7_45135775_45135990	0.57	Flt3l	FMS-like tyrosine kinase 3 ligand	174	0.6
chr2_30700410_30700587	0.57	Gm14488	predicted gene 14488	16545	0.13
chr4_150465668_150465829	0.57	Rere	arginine glutamic acid dipeptide (RE) repeats	22645	0.22
chr3_18157205_18157356	0.57	Gm23686	predicted gene, 23686	20345	0.21
chr17_28513542_28513712	0.57	Fkbp5	FK506 binding protein 5	2270	0.13
chr5_99240951_99241102	0.57	Rasgef1b	RasGEF domain family, member 1B	2214	0.36
chr3_118644387_118644538	0.56	Dpyd	dihydropyrimidine dehydrogenase	82276	0.09
chr8_22040011_22040349	0.56	Atp7b	ATPase, Cu++ transporting, beta polypeptide	19839	0.12
chr9_45106724_45106908	0.56	Jaml	junction adhesion molecule like	2956	0.12
chr8_35409885_35410137	0.56	Gm45301	predicted gene 45301	505	0.77
chr13_54564355_54564568	0.56	4833439L19Rik	RIKEN cDNA 4833439L19 gene	830	0.44
chr15_78456851_78457002	0.55	Tmprss6	transmembrane serine protease 6	8417	0.11
chr18_75371968_75372846	0.55	Smad7	SMAD family member 7	2431	0.3
chr4_120973741_120974003	0.55	Mir7015	microRNA 7015	550	0.63
chr17_83831307_83831458	0.55	Haao	3-hydroxyanthranilate 3,4-dioxygenase	4586	0.2
chr19_18145861_18146289	0.55	Gm18610	predicted gene, 18610	59720	0.14
chr18_4997068_4997219	0.55	Svil	supervillin	2207	0.44
chr8_12896613_12896795	0.55	Gm15353	predicted gene 15353	12978	0.11
chr6_59412884_59413285	0.55	Gprin3	GPRIN family member 3	13210	0.29
chr10_69268280_69268446	0.55	Rhobtb1	Rho-related BTB domain containing 1	2726	0.27
chr12_103311070_103311221	0.55	Fam181a	family with sequence similarity 181, member A	170	0.92
chr1_153918898_153919085	0.55	Glul	glutamate-ammonia ligase (glutamine synthetase)	12948	0.1
chr8_45236482_45236633	0.54	F11	coagulation factor XI	25474	0.15
chr8_127077215_127077366	0.54	Pard3	par-3 family cell polarity regulator	4050	0.23
chr2_31484723_31485077	0.54	Ass1	argininosuccinate synthetase 1	12872	0.18
chr9_48822622_48822793	0.54	Zbtb16	zinc finger and BTB domain containing 16	13238	0.23
chr5_112299397_112299785	0.54	Tpst2	protein-tyrosine sulfotransferase 2	4305	0.13
chr10_127535491_127535722	0.54	Nxph4	neurexophilin 4	1047	0.34
chrY_90807930_90808086	0.53	Gm47283	predicted gene, 47283	17557	0.16
chr11_117599771_117599931	0.53	2900041M22Rik	RIKEN cDNA 2900041M22 gene	11396	0.18
chr15_82433343_82433494	0.53	Cyp2d9	cytochrome P450, family 2, subfamily d, polypeptide 9	19	0.57
chr19_47317044_47317343	0.53	Sh3pxd2a	SH3 and PX domains 2A	2442	0.27
chr4_31964283_31964752	0.53	Map3k7	mitogen-activated protein kinase kinase kinase 7	254	0.93
chr18_75675824_75676322	0.53	Ctif	CBP80/20-dependent translation initiation factor	21481	0.23
chr5_112843087_112843449	0.52	Myo18b	myosin XVIIIb	28318	0.17
chr1_100298140_100298304	0.52	Gm29667	predicted gene 29667	15431	0.18
chr10_45002693_45003320	0.52	Gm4795	predicted pseudogene 4795	3104	0.23
chr15_59656218_59656369	0.51	Trib1	tribbles pseudokinase 1	7640	0.21
chr2_154602500_154602684	0.51	Pxmp4	peroxisomal membrane protein 4	1096	0.34
chr3_121429782_121429933	0.51	Gm42929	predicted gene 42929	1811	0.23
chr19_41982414_41982837	0.51	Ubtd1	ubiquitin domain containing 1	862	0.39
chr2_52580732_52580891	0.51	Cacnb4	calcium channel, voltage-dependent, beta 4 subunit	22244	0.17
chr2_23571405_23571576	0.51	Spopl	speckle-type BTB/POZ protein-like	488	0.85
chr3_94382765_94382916	0.51	Rorc	RAR-related orphan receptor gamma	5324	0.07
chr7_98355533_98355727	0.51	Tsku	tsukushi, small leucine rich proteoglycan	4449	0.2
chr1_191072716_191073064	0.50	Gm38188	predicted gene, 38188	5790	0.11
chr3_41021798_41021949	0.50	Larp1b	La ribonucleoprotein domain family, member 1B	66	0.96
chr8_56232954_56233105	0.50	Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	61556	0.13
chr3_94383740_94383891	0.50	Rorc	RAR-related orphan receptor gamma	6299	0.07
chr6_21822757_21822949	0.50	Tspan12	tetraspanin 12	28975	0.16
chr1_70918162_70918313	0.50	Gm16236	predicted gene 16236	121793	0.06
chr3_107793813_107794000	0.50	Gm43233	predicted gene 43233	12050	0.12
chr11_115246492_115246668	0.49	Gm25837	predicted gene, 25837	6698	0.11
chr7_97424749_97424908	0.49	Thrsp	thyroid hormone responsive	7098	0.13
chr8_91427905_91428056	0.49	Gm45292	predicted gene 45292	22326	0.13
chr9_57629762_57629913	0.49	Csk	c-src tyrosine kinase	1076	0.36
chr12_103950977_103951332	0.48	Serpina1e	serine (or cysteine) peptidase inhibitor, clade A, member 1E	5744	0.12
chr14_65615417_65615662	0.48	Nuggc	nuclear GTPase, germinal center associated	10272	0.2
chr8_94390548_94390834	0.48	Herpud1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	99	0.94
chr2_109914519_109914676	0.48	Platr8	pluripotency associated transcript 8	1278	0.42
chr13_93675182_93675342	0.48	Dmgdh	dimethylglycine dehydrogenase precursor	829	0.4
chr10_127512055_127512229	0.48	Ndufa4l2	Ndufa4, mitochondrial complex associated like 2	2825	0.14
chr7_43873338_43873505	0.48	Klk4	kallikrein related-peptidase 4 (prostase, enamel matrix, prostate)	7739	0.07
chr16_42972452_42972603	0.47	Ndufs5-ps	NADH:ubiquinone oxidoreductase core subunit S5, pseudogene	16896	0.22
chr11_80154280_80154437	0.47	Adap2	ArfGAP with dual PH domains 2	242	0.89
chr17_84838075_84838259	0.47	Gm49981	predicted gene, 49981	2129	0.27
chr9_21244783_21245089	0.47	Gm48303	predicted gene, 48303	2777	0.12
chr6_34176282_34176719	0.47	Slc35b4	solute carrier family 35, member B4	470	0.78
chr17_46818808_46819143	0.47	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	6790	0.14
chr13_63399974_63400125	0.47	Fancc	Fanconi anemia, complementation group C	1755	0.26
chr14_29016495_29016840	0.47	Lrtm1	leucine-rich repeats and transmembrane domains 1	1541	0.4
chr17_45594866_45595446	0.47	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	346	0.75
chr16_44726728_44726910	0.47	Nepro	nucleolus and neural progenitor protein	300	0.89
chr9_108307554_108308248	0.46	Rhoa	ras homolog family member A	1072	0.25
chr4_76366206_76366441	0.46	Ptprd	protein tyrosine phosphatase, receptor type, D	22080	0.21
chr19_7191764_7192280	0.46	Otub1	OTU domain, ubiquitin aldehyde binding 1	8442	0.13
chr6_90706299_90706473	0.46	Iqsec1	IQ motif and Sec7 domain 1	10143	0.15
chr14_59199574_59199727	0.46	Rcbtb1	regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1	1559	0.37
chr7_66600882_66601072	0.45	Gm44610	predicted gene 44610	18171	0.15
chr2_163558490_163558641	0.45	Hnf4a	hepatic nuclear factor 4, alpha	8482	0.13
chr17_24856120_24856323	0.45	Hagh	hydroxyacyl glutathione hydrolase	1980	0.15
chr7_63899068_63899509	0.45	Gm27252	predicted gene 27252	1314	0.37
chr7_65469453_65469620	0.45	Gm44792	predicted gene 44792	11685	0.21
chr9_75010713_75011049	0.45	Arpp19	cAMP-regulated phosphoprotein 19	26733	0.14
chr6_87261053_87261232	0.45	Gm44417	predicted gene, 44417	5534	0.13
chr4_9846537_9846689	0.45	Gdf6	growth differentiation factor 6	2241	0.36
chr12_84185790_84185961	0.45	Gm19327	predicted gene, 19327	1931	0.2
chr6_23386863_23387077	0.45	Cadps2	Ca2+-dependent activator protein for secretion 2	31051	0.21
chr12_17471269_17471420	0.45	Gm36752	predicted gene, 36752	34726	0.14
chr10_68092347_68092553	0.45	Arid5b	AT rich interactive domain 5B (MRF1-like)	44176	0.14
chr15_59065322_59065483	0.45	Mtss1	MTSS I-BAR domain containing 1	9938	0.23
chr6_124500752_124500905	0.45	Gm44096	predicted gene, 44096	6460	0.1
chr9_44096490_44096809	0.45	Usp2	ubiquitin specific peptidase 2	3975	0.08
chr7_84669353_84669504	0.44	Zfand6	zinc finger, AN1-type domain 6	9923	0.17
chr3_27751240_27751399	0.44	Fndc3b	fibronectin type III domain containing 3B	40012	0.19
chr11_86582448_86582611	0.44	Mir21a	microRNA 21a	1629	0.3
chr10_24159731_24159882	0.44	Stx7	syntaxin 7	7359	0.14
chr2_19628072_19628252	0.44	Gm13348	predicted gene 13348	8824	0.15
chr14_121329448_121329600	0.44	Stk24	serine/threonine kinase 24	26049	0.18
chr14_21195621_21195893	0.44	Adk	adenosine kinase	119605	0.05
chr1_120061736_120061887	0.43	Tmem37	transmembrane protein 37	12263	0.17
chr6_108476815_108477313	0.43	Gm44101	predicted gene, 44101	4489	0.19
chr5_136960851_136961002	0.43	Fis1	fission, mitochondrial 1	1151	0.29
chr1_69019711_69019872	0.43	Gm16076	predicted gene 16076	86949	0.09
chr1_127731165_127731558	0.43	Acmsd	amino carboxymuconate semialdehyde decarboxylase	1948	0.33
chr15_76606976_76607461	0.43	Cpsf1	cleavage and polyadenylation specific factor 1	271	0.77
chr7_81542234_81542406	0.43	Gm37829	predicted gene, 37829	9799	0.1
chr9_48724021_48724519	0.43	Zbtb16	zinc finger and BTB domain containing 16	111675	0.06
chr3_49739192_49739373	0.43	Pcdh18	protocadherin 18	16182	0.2
chr11_101354253_101354618	0.42	Gm11619	predicted gene 11619	890	0.23
chr14_17823236_17823387	0.42	Gm48320	predicted gene, 48320	52189	0.17
chr9_31926942_31927111	0.42	Gm3756	predicted gene 3756	9774	0.15
chr6_108665497_108666008	0.42	Bhlhe40	basic helix-loop-helix family, member e40	2706	0.23
chr1_91463744_91463928	0.42	Per2	period circadian clock 2	4512	0.13
chr11_5904597_5904748	0.42	Gck	glucokinase	2585	0.17
chr15_61987418_61987569	0.42	Myc	myelocytomatosis oncogene	71	0.98
chr1_58714678_58714972	0.41	Cflar	CASP8 and FADD-like apoptosis regulator	939	0.46
chr6_17465028_17465179	0.41	Met	met proto-oncogene	996	0.59
chr15_58987050_58987409	0.41	4930544F09Rik	RIKEN cDNA 4930544F09 gene	3093	0.22
chr5_102010214_102010423	0.41	Wdfy3	WD repeat and FYVE domain containing 3	28760	0.16
chr12_71841530_71841895	0.41	Gm7985	predicted gene 7985	5579	0.22
chr2_27698448_27698634	0.41	Rxra	retinoid X receptor alpha	10751	0.26
chr10_26373742_26373973	0.41	L3mbtl3	L3MBTL3 histone methyl-lysine binding protein	99	0.96
chr7_100010437_100010820	0.41	Chrdl2	chordin-like 2	714	0.6
chr8_70816974_70817162	0.41	Il12rb1	interleukin 12 receptor, beta 1	3852	0.09

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Smad2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0010046	response to mycotoxin(GO:0010046)
0.2	0.6	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.2	0.5	GO:0042851	L-alanine metabolic process(GO:0042851)
0.2	0.5	GO:0045218	zonula adherens maintenance(GO:0045218)
0.2	0.5	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1	0.4	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.5	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.7	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.4	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1	0.6	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1	0.3	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.3	GO:0090290	positive regulation of osteoclast proliferation(GO:0090290)
0.1	1.2	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.1	0.4	GO:0018103	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.1	0.9	GO:0055091	phospholipid homeostasis(GO:0055091)
0.1	0.4	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1	0.1	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.1	0.3	GO:1903416	response to glycoside(GO:1903416)
0.1	0.3	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.1	0.3	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.1	0.4	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.1	GO:0009139	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	0.2	GO:0009730	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.2	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.1	0.2	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.1	0.9	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.1	0.3	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.1	0.2	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.3	GO:0051697	protein delipidation(GO:0051697)
0.1	0.6	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.2	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.2	GO:0018992	germ-line sex determination(GO:0018992)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.1	0.4	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.2	GO:0009211	pyrimidine deoxyribonucleoside triphosphate metabolic process(GO:0009211)
0.1	0.3	GO:0042866	pyruvate biosynthetic process(GO:0042866)
0.1	0.2	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.1	0.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1	0.2	GO:0006597	spermine biosynthetic process(GO:0006597)
0.1	0.2	GO:1900041	negative regulation of interleukin-2 secretion(GO:1900041)
0.1	0.2	GO:0042117	monocyte activation(GO:0042117)
0.1	0.2	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.1	0.3	GO:0051136	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.1	0.2	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.1	0.2	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.1	0.2	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.1	0.2	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.1	0.2	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1	1.2	GO:0036075	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.1	0.3	GO:0086013	membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.1	0.5	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	0.2	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.0	GO:0034616	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.3	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.1	GO:0033058	directional locomotion(GO:0033058)
0.0	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.2	GO:0036233	glycine import(GO:0036233)
0.0	0.1	GO:0043366	beta selection(GO:0043366)
0.0	0.2	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.2	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.4	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.2	GO:0015867	ATP transport(GO:0015867)
0.0	0.2	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.2	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.2	GO:0006407	rRNA export from nucleus(GO:0006407)
0.0	0.2	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:0061511	centriole elongation(GO:0061511)
0.0	0.1	GO:0006680	glucosylceramide catabolic process(GO:0006680)
0.0	0.2	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.5	GO:0035584	calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.4	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.2	GO:1903147	negative regulation of mitophagy(GO:1903147)
0.0	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.2	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.1	GO:0021776	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.3	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.5	GO:0032306	regulation of prostaglandin secretion(GO:0032306)
0.0	0.1	GO:0019346	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.3	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.2	GO:0033085	negative regulation of T cell differentiation in thymus(GO:0033085)
0.0	0.1	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.0	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.3	GO:0046784	viral mRNA export from host cell nucleus(GO:0046784)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.2	GO:0010642	negative regulation of platelet-derived growth factor receptor signaling pathway(GO:0010642)
0.0	0.2	GO:0032962	positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0	0.4	GO:0048537	mucosal-associated lymphoid tissue development(GO:0048537) Peyer's patch development(GO:0048541)
0.0	0.1	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.3	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.4	GO:0043249	erythrocyte maturation(GO:0043249)
0.0	0.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.2	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.2	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.2	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.1	GO:0051725	protein de-ADP-ribosylation(GO:0051725)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.1	GO:0031944	negative regulation of glucocorticoid metabolic process(GO:0031944) negative regulation of glucocorticoid biosynthetic process(GO:0031947) negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.1	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.3	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.1	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.2	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.2	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	0.1	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.2	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.2	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:1905206	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:0034374	low-density lipoprotein particle remodeling(GO:0034374)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0090310	negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0	0.6	GO:0071800	podosome assembly(GO:0071800)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.2	GO:0070587	negative regulation of heterotypic cell-cell adhesion(GO:0034115) regulation of cell-cell adhesion involved in gastrulation(GO:0070587)
0.0	0.3	GO:0045540	regulation of cholesterol biosynthetic process(GO:0045540)
0.0	0.1	GO:0042701	progesterone secretion(GO:0042701)
0.0	0.1	GO:0086023	adrenergic receptor signaling pathway involved in heart process(GO:0086023)
0.0	0.2	GO:0034720	histone H3-K4 demethylation(GO:0034720)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.2	GO:0006558	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.3	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:0048633	positive regulation of skeletal muscle tissue growth(GO:0048633)
0.0	0.2	GO:0097411	hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0	0.1	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:1905048	regulation of metallopeptidase activity(GO:1905048)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.5	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0072553	terminal button organization(GO:0072553)
0.0	0.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.1	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.1	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.2	GO:0006689	ganglioside catabolic process(GO:0006689)
0.0	0.1	GO:0060283	negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.5	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.0	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.0	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.2	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.1	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.4	GO:0070884	regulation of calcineurin-NFAT signaling cascade(GO:0070884)
0.0	0.0	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.0	GO:1900739	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.1	GO:0006555	methionine metabolic process(GO:0006555)
0.0	0.1	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.1	GO:2000653	regulation of genetic imprinting(GO:2000653)
0.0	0.1	GO:0051531	NFAT protein import into nucleus(GO:0051531)
0.0	0.2	GO:0043569	negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.2	GO:0045631	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.0	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.2	GO:0031017	exocrine pancreas development(GO:0031017)
0.0	0.1	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.5	GO:0000470	maturation of LSU-rRNA(GO:0000470)
0.0	0.0	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.1	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.1	GO:0035627	ceramide transport(GO:0035627)
0.0	0.2	GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0	0.2	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.2	GO:0032225	regulation of synaptic transmission, dopaminergic(GO:0032225)
0.0	0.1	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.2	GO:0000729	DNA double-strand break processing(GO:0000729)
0.0	0.1	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0	0.1	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.1	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb(GO:0022028)
0.0	0.1	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0	0.1	GO:0045199	maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0	0.1	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.6	GO:0045747	positive regulation of Notch signaling pathway(GO:0045747)
0.0	0.1	GO:0032460	negative regulation of protein oligomerization(GO:0032460)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.1	GO:0002115	store-operated calcium entry(GO:0002115)
0.0	0.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0033762	response to glucagon(GO:0033762)
0.0	0.2	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0	0.1	GO:0043201	response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0	0.5	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0	0.0	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.0	0.1	GO:0030091	protein repair(GO:0030091)
0.0	0.1	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.0	0.0	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	0.0	GO:0045091	regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045091) negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:0035095	behavioral response to nicotine(GO:0035095)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.1	GO:0035928	rRNA import into mitochondrion(GO:0035928)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.1	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0007529	establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.0	0.1	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.1	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.2	GO:0060712	spongiotrophoblast layer development(GO:0060712)
0.0	0.1	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.4	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.0	GO:0090031	positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.0	0.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.1	GO:0006703	estrogen biosynthetic process(GO:0006703)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.1	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.1	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:1990036	calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0	0.0	GO:0018916	nitrobenzene metabolic process(GO:0018916)
0.0	0.1	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0097090	presynaptic membrane organization(GO:0097090)
0.0	0.1	GO:0050955	thermoception(GO:0050955)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.0	GO:0046070	dGTP metabolic process(GO:0046070)
0.0	0.0	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.0	GO:1903935	response to sodium arsenite(GO:1903935)
0.0	0.1	GO:0048680	positive regulation of axon regeneration(GO:0048680)
0.0	0.1	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0070934	CRD-mediated mRNA stabilization(GO:0070934)
0.0	0.0	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0002386	immune response in mucosal-associated lymphoid tissue(GO:0002386)
0.0	0.1	GO:0016576	histone dephosphorylation(GO:0016576)
0.0	0.1	GO:2000369	regulation of clathrin-mediated endocytosis(GO:2000369)
0.0	0.1	GO:0060177	regulation of angiotensin metabolic process(GO:0060177)
0.0	0.2	GO:0070233	negative regulation of T cell apoptotic process(GO:0070233)
0.0	0.0	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.2	GO:0045836	positive regulation of meiotic nuclear division(GO:0045836)
0.0	0.0	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0032825	positive regulation of natural killer cell differentiation(GO:0032825)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.1	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.0	GO:0042518	negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0	0.2	GO:0018345	protein palmitoylation(GO:0018345)
0.0	0.0	GO:1903431	positive regulation of cell maturation(GO:1903431)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0032927	positive regulation of activin receptor signaling pathway(GO:0032927)
0.0	0.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.2	GO:0043982	histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)
0.0	0.1	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.0	0.0	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.1	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.0	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.0	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.0	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.1	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.0	GO:0098735	positive regulation of the force of heart contraction(GO:0098735)
0.0	0.2	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.0	GO:0045829	negative regulation of isotype switching(GO:0045829)
0.0	0.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.1	GO:0045086	positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0	0.0	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:1903275	positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.0	0.0	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.3	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.1	GO:0045760	positive regulation of action potential(GO:0045760)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.0	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.0	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.0	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.0	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.0	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.0	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.1	GO:0015816	glycine transport(GO:0015816)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0015677	copper ion import(GO:0015677)
0.0	0.5	GO:0035383	acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.3	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.0	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.0	GO:0071694	protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0	0.0	GO:0015888	thiamine transport(GO:0015888)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.0	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0034770	histone H4-K20 methylation(GO:0034770)
0.0	0.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0046340	diacylglycerol catabolic process(GO:0046340)
0.0	0.0	GO:1901069	guanosine-containing compound catabolic process(GO:1901069)
0.0	0.0	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.0	GO:0010915	regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0	0.0	GO:0090110	cargo loading into COPII-coated vesicle(GO:0090110)
0.0	0.2	GO:0006270	DNA replication initiation(GO:0006270)
0.0	0.1	GO:0030449	regulation of complement activation(GO:0030449)
0.0	0.0	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.0	GO:0070343	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.0	GO:1903998	regulation of eating behavior(GO:1903998) negative regulation of eating behavior(GO:1903999)
0.0	0.1	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.0	0.2	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.0	0.1	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.1	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0002760	positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0	0.0	GO:2000836	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.0	GO:0006553	lysine metabolic process(GO:0006553)
0.0	0.1	GO:0042136	neurotransmitter biosynthetic process(GO:0042136)
0.0	0.0	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.0	GO:0061641	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0031088	platelet dense granule membrane(GO:0031088)
0.2	0.5	GO:0097413	Lewy body(GO:0097413)
0.2	1.7	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.1	0.3	GO:0005879	axonemal microtubule(GO:0005879)
0.1	0.5	GO:0005915	zonula adherens(GO:0005915)
0.1	0.3	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.6	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0031094	platelet dense tubular network(GO:0031094)
0.1	0.7	GO:0070852	cell body fiber(GO:0070852)
0.1	0.2	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.1	0.2	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.1	1.0	GO:0002102	podosome(GO:0002102)
0.1	0.4	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0070522	ERCC4-ERCC1 complex(GO:0070522)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.3	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.2	GO:0035363	histone locus body(GO:0035363)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.4	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.6	GO:0031233	intrinsic component of external side of plasma membrane(GO:0031233)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0030015	CCR4-NOT core complex(GO:0030015)
0.0	0.2	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.3	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.3	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0	1.2	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.2	GO:0005750	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0031228	intrinsic component of Golgi membrane(GO:0031228)
0.0	0.0	GO:1990696	USH2 complex(GO:1990696)
0.0	0.1	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.7	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.3	GO:0032580	Golgi cisterna membrane(GO:0032580)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.2	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.2	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0005751	mitochondrial respiratory chain complex IV(GO:0005751)
0.0	0.0	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.2	GO:0001891	phagocytic cup(GO:0001891)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.2	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.0	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.1	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0034388	Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	1.1	GO:0017053	transcriptional repressor complex(GO:0017053)
0.0	0.6	GO:0005637	nuclear inner membrane(GO:0005637)
0.0	0.5	GO:0000118	histone deacetylase complex(GO:0000118)
0.0	0.2	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)
0.0	0.1	GO:0000127	transcription factor TFIIIC complex(GO:0000127)
0.0	0.7	GO:0019005	SCF ubiquitin ligase complex(GO:0019005)
0.0	0.1	GO:0044613	nuclear pore central transport channel(GO:0044613)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)
0.0	0.1	GO:0005845	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.0	GO:0044462	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.3	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0030430	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0070069	cytochrome complex(GO:0070069)
0.0	0.1	GO:0036057	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:1990393	3M complex(GO:1990393)
0.0	0.2	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0097542	ciliary tip(GO:0097542)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:0031462	Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.1	GO:0033391	chromatoid body(GO:0033391)
0.0	0.1	GO:0071541	eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0	0.2	GO:0030904	retromer complex(GO:0030904)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.0	GO:0000814	ESCRT II complex(GO:0000814)
0.0	0.1	GO:0030877	beta-catenin destruction complex(GO:0030877)
0.0	0.1	GO:0048188	Set1C/COMPASS complex(GO:0048188)
0.0	0.1	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.2	GO:0046930	pore complex(GO:0046930)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.4	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.2	0.6	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2	0.4	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.1	0.4	GO:0019862	IgA binding(GO:0019862)
0.1	0.1	GO:0042813	Wnt-activated receptor activity(GO:0042813)
0.1	0.3	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.3	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.1	0.5	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1	0.3	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1	0.3	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.1	0.3	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.3	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1	1.0	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1	0.3	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.1	0.2	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.1	0.2	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1	0.5	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	1.0	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.1	0.6	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.2	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1	0.3	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.2	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	0.2	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.1	0.2	GO:0045503	dynein light chain binding(GO:0045503)
0.1	0.3	GO:0086008	voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.4	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.1	0.2	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.3	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0008503	benzodiazepine receptor activity(GO:0008503)
0.0	0.2	GO:0000405	bubble DNA binding(GO:0000405)
0.0	0.2	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.7	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.2	GO:0004784	superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0	0.3	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.2	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.2	GO:0052794	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.2	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0031749	D2 dopamine receptor binding(GO:0031749)
0.0	0.2	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.5	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.4	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.2	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.4	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.6	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0004340	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.1	GO:0016941	natriuretic peptide receptor activity(GO:0016941)
0.0	0.2	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.3	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.2	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.2	GO:0032453	histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.3	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.3	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.4	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.4	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.2	GO:0015288	porin activity(GO:0015288)
0.0	0.3	GO:0070402	NADPH binding(GO:0070402)
0.0	0.8	GO:0061631	ubiquitin conjugating enzyme activity(GO:0061631)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.2	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.1	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0003988	acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0	0.1	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.2	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:0052759	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0019976	interleukin-2 binding(GO:0019976)
0.0	0.1	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.2	GO:0055106	ubiquitin-protein transferase regulator activity(GO:0055106)
0.0	0.1	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.7	GO:0070888	E-box binding(GO:0070888)
0.0	0.2	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.2	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.2	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.2	GO:0070513	death domain binding(GO:0070513)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.3	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.7	GO:0043548	phosphatidylinositol 3-kinase binding(GO:0043548)
0.0	0.5	GO:0008483	transaminase activity(GO:0008483)
0.0	0.1	GO:0005280	hydrogen:amino acid symporter activity(GO:0005280)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.2	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0086006	voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.2	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.2	GO:0051183	vitamin transporter activity(GO:0051183)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.2	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.2	GO:0004844	uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.3	GO:0004889	acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.2	GO:0008413	8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413)
0.0	0.1	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.0	0.0	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	1.1	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.0	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.2	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0015269	calcium-activated potassium channel activity(GO:0015269)
0.0	0.6	GO:0003730	mRNA 3'-UTR binding(GO:0003730)
0.0	0.0	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.2	GO:0070273	phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.0	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0000774	adenyl-nucleotide exchange factor activity(GO:0000774)
0.0	0.1	GO:0051765	inositol tetrakisphosphate kinase activity(GO:0051765)
0.0	0.0	GO:0004532	3'-5'-exoribonuclease activity(GO:0000175) exoribonuclease activity(GO:0004532) exoribonuclease activity, producing 5'-phosphomonoesters(GO:0016896)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.3	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.3	GO:0019706	protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.4	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.2	GO:0032183	SUMO binding(GO:0032183)
0.0	0.1	GO:0008113	peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.0	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.3	GO:0001106	RNA polymerase II transcription corepressor activity(GO:0001106)
0.0	0.2	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.3	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.2	GO:0060590	ATPase activator activity(GO:0001671) ATPase regulator activity(GO:0060590)
0.0	0.1	GO:0004551	nucleotide diphosphatase activity(GO:0004551)
0.0	0.4	GO:0043914	NADPH:sulfur oxidoreductase activity(GO:0043914)
0.0	0.2	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.2	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0	0.0	GO:0004691	cAMP-dependent protein kinase activity(GO:0004691)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.1	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.2	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.1	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.0	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.0	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.0	GO:0010485	H4 histone acetyltransferase activity(GO:0010485)
0.0	0.2	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.0	GO:0050220	prostaglandin-E synthase activity(GO:0050220)
0.0	0.0	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.3	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.2	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.0	GO:0008147	structural constituent of bone(GO:0008147)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.0	0.2	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.5	ST P38 MAPK PATHWAY	p38 MAPK Pathway
0.0	0.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.7	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.1	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.3	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.0	PID IL8 CXCR2 PATHWAY	IL8- and CXCR2-mediated signaling events
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.8	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.0	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.6	PID MYC PATHWAY	C-MYC pathway
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	0.3	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.2	PID P73PATHWAY	p73 transcription factor network
0.0	0.1	PID S1P META PATHWAY	Sphingosine 1-phosphate (S1P) pathway
0.0	0.5	PID ALK1 PATHWAY	ALK1 signaling events
0.0	0.1	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0	0.1	PID LYSOPHOSPHOLIPID PATHWAY	LPA receptor mediated events
0.0	0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.3	PID FOXO PATHWAY	FoxO family signaling
0.0	0.1	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	0.1	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.1	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	0.2	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.0	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.0	0.2	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.7	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.1	0.1	REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS	Genes involved in Membrane binding and targetting of GAG proteins
0.1	1.0	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.2	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.3	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	0.3	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.7	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.1	REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA	Genes involved in G beta:gamma signalling through PLC beta
0.0	0.8	REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES	Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0	0.4	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.7	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	0.3	REACTOME GABA A RECEPTOR ACTIVATION	Genes involved in GABA A receptor activation
0.0	0.3	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.0	0.3	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.3	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.3	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.2	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.3	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.2	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.4	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.1	REACTOME SCF BETA TRCP MEDIATED DEGRADATION OF EMI1	Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.0	0.4	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.2	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.4	REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER	Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0	0.0	REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR	Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0	0.1	REACTOME LIGAND GATED ION CHANNEL TRANSPORT	Genes involved in Ligand-gated ion channel transport
0.0	0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.0	0.2	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.0	0.4	REACTOME ACTIVATION OF GENES BY ATF4	Genes involved in Activation of Genes by ATF4
0.0	0.1	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.2	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.2	REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII	Genes involved in CREB phosphorylation through the activation of CaMKII
0.0	0.2	REACTOME INITIAL TRIGGERING OF COMPLEMENT	Genes involved in Initial triggering of complement
0.0	0.2	REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING	Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.2	REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS	Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	0.1	REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS	Genes involved in Elevation of cytosolic Ca2+ levels
0.0	0.2	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME CD28 DEPENDENT VAV1 PATHWAY	Genes involved in CD28 dependent Vav1 pathway
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.1	REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT	Genes involved in Organic cation/anion/zwitterion transport
0.0	0.3	REACTOME AMINE COMPOUND SLC TRANSPORTERS	Genes involved in Amine compound SLC transporters
0.0	0.2	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.0	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.0	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery

Results for Smad2

Z-value: 2.38

Motif logo

Transcription factors associated with Smad2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Smad2 motif across conditions

Conditions sorted by the z-value of the Smad2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Smad2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: