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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Sox1

Z-value: 0.83

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Transcription factors associated with Sox1

Gene Symbol Gene ID Gene Info
Sox1
ENSMUSG00000096014.1 SRY (sex determining region Y)-box 1

Activity of the Sox1 motif across conditions

Conditions sorted by the z-value of the Sox1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr19_16179580_16179731 1.09 E030024N20Rik
 RIKEN cDNA E030024N20 gene
 14850
 0.2
chr7_98351056_98351207 0.98 Tsku
 tsukushi, small leucine rich proteoglycan
 8948
 0.17
chr19_29520625_29520778 0.88 A930007I19Rik
 RIKEN cDNA A930007I19 gene
 269
 0.89
chr10_77011600_77011778 0.79 Gm10787
 predicted gene 10787
 306
 0.84
chr4_101352284_101352479 0.75 0610043K17Rik
 RIKEN cDNA 0610043K17 gene
 1402
 0.26
chr12_80010993_80011167 0.62 Gm8275
 predicted gene 8275
 31229
 0.14
chr5_86918463_86918614 0.61 Gm25211
 predicted gene, 25211
 2216
 0.17
chr9_31209643_31210005 0.61 Aplp2
 amyloid beta (A4) precursor-like protein 2
 1963
 0.34
chr1_85325110_85325261 0.60 Gm16025
 predicted gene 16025
 1544
 0.27
chr19_44401346_44401497 0.60 Scd1
 stearoyl-Coenzyme A desaturase 1
 5269
 0.16
chr3_31075182_31075333 0.52 Skil
 SKI-like
 19801
 0.16
chr11_90184166_90184514 0.51 n-R5s72
 nuclear encoded rRNA 5S 72
 787
 0.57
chr14_9492003_9492160 0.51 Gm48371
 predicted gene, 48371
 22526
 0.26
chr3_112120839_112120990 0.51 Gm25519
 predicted gene, 25519
 78127
 0.1
chr2_113534474_113534796 0.49 Gm13964
 predicted gene 13964
 30601
 0.17
chr1_162892544_162892705 0.46 Fmo2
 flavin containing monooxygenase 2
 5860
 0.19
chr2_71212098_71212533 0.45 Dync1i2
 dynein cytoplasmic 1 intermediate chain 2
 311
 0.92
chr11_60205641_60205948 0.43 Srebf1
 sterol regulatory element binding transcription factor 1
 318
 0.81
chr19_16029083_16029234 0.43 Rpl37-ps1
 ribosomal protein 37, pseudogene 1
 3707
 0.24
chr3_88173707_88173903 0.43 1700113A16Rik
 RIKEN cDNA 1700113A16 gene
 3887
 0.11
chr4_44976139_44976290 0.42 Gm12679
 predicted gene 12679
 2105
 0.19
chr5_145454830_145455000 0.42 Cyp3a16
 cytochrome P450, family 3, subfamily a, polypeptide 16
 14808
 0.16
chr1_74751129_74751319 0.41 Prkag3
 protein kinase, AMP-activated, gamma 3 non-catalytic subunit
 2003
 0.21
chr9_103209178_103209657 0.41 Trf
 transferrin
 2589
 0.24
chr12_40564154_40564324 0.40 Dock4
 dedicator of cytokinesis 4
 117903
 0.06
chr1_151339242_151339404 0.40 Gm10138
 predicted gene 10138
 4759
 0.16
chr7_68140395_68140567 0.40 Igf1r
 insulin-like growth factor I receptor
 8109
 0.26
chr12_32764273_32764609 0.40 Gm18726
 predicted gene, 18726
 54280
 0.11
chr2_31514522_31514710 0.39 Ass1
 argininosuccinate synthetase 1
 3874
 0.21
chr7_67655501_67655709 0.39 Ttc23
 tetratricopeptide repeat domain 23
 158
 0.93
chr5_66035556_66035796 0.39 Rbm47
 RNA binding motif protein 47
 18876
 0.11
chr18_61798684_61798836 0.38 Afap1l1
 actin filament associated protein 1-like 1
 12058
 0.18
chr3_94699549_94699901 0.38 Selenbp2
 selenium binding protein 2
 6066
 0.12
chr3_116302483_116302634 0.38 Gm29151
 predicted gene 29151
 47545
 0.11
chr5_140118402_140118733 0.38 Mad1l1
 MAD1 mitotic arrest deficient 1-like 1
 3101
 0.21
chr6_149057714_149057872 0.37 Gm49058
 predicted gene, 49058
 3945
 0.12
chr5_49060180_49060366 0.37 Gm43047
 predicted gene 43047
 9730
 0.1
chr4_60245923_60246074 0.37 Mup-ps3
 major urinary protein, pseudogene 3
 8653
 0.19
chr8_45630130_45630742 0.37 Sorbs2
 sorbin and SH3 domain containing 2
 2235
 0.3
chr17_48484838_48484989 0.36 Unc5cl
 unc-5 family C-terminal like
 22509
 0.13
chr4_59006708_59006875 0.36 Gm20503
 predicted gene 20503
 3581
 0.16
chr9_35209800_35209963 0.35 Foxred1
 FAD-dependent oxidoreductase domain containing 1
 1016
 0.31
chr4_152264194_152264355 0.35 Gpr153
 G protein-coupled receptor 153
 9958
 0.12
chr5_117165254_117165405 0.35 n-R5s174
 nuclear encoded rRNA 5S 174
 31226
 0.11
chr19_10904836_10905155 0.35 Prpf19
 pre-mRNA processing factor 19
 4713
 0.11
chr4_61167643_61167862 0.34 Mup-ps9
 major urinary protein, pseudogene 9
 4689
 0.27
chr1_160781397_160781614 0.34 Rabgap1l
 RAB GTPase activating protein 1-like
 11433
 0.12
chr9_102354784_102354966 0.34 Ephb1
 Eph receptor B1
 182
 0.95
chr4_53227508_53227716 0.34 4930412L05Rik
 RIKEN cDNA 4930412L05 gene
 9755
 0.17
chr13_3634828_3634979 0.34 Asb13
 ankyrin repeat and SOCS box-containing 13
 804
 0.58
chr4_61248201_61248394 0.33 Mup-ps10
 major urinary protein, pseudogene 10
 4720
 0.21
chr13_96648408_96648591 0.33 Hmgcr
 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
 4304
 0.17
chr17_86393949_86394100 0.32 Prkce
 protein kinase C, epsilon
 96538
 0.07
chr10_57848460_57848621 0.32 Smpdl3a
 sphingomyelin phosphodiesterase, acid-like 3A
 53972
 0.13
chr2_31515291_31515653 0.32 Ass1
 argininosuccinate synthetase 1
 3018
 0.23
chr15_65337961_65338116 0.31 Gm49242
 predicted gene, 49242
 137476
 0.05
chr2_26663667_26663830 0.31 Lcn4
 lipocalin 4
 7534
 0.11
chr3_95885104_95885275 0.31 Ciart
 circadian associated repressor of transcription
 2938
 0.1
chr2_163568842_163568993 0.31 Hnf4a
 hepatic nuclear factor 4, alpha
 18834
 0.12
chr4_97905915_97906126 0.30 Nfia
 nuclear factor I/A
 5013
 0.32
chr7_16598127_16598332 0.30 Gm29443
 predicted gene 29443
 15595
 0.09
chr10_124590350_124590536 0.30 4930503E24Rik
 RIKEN cDNA 4930503E24 gene
 67005
 0.14
chr5_89493650_89493829 0.30 Gm6366
 predicted gene 6366
 6238
 0.21
chr1_52004207_52004365 0.29 Stat4
 signal transducer and activator of transcription 4
 3957
 0.2
chr5_87334492_87334755 0.29 Ugt2a3
 UDP glucuronosyltransferase 2 family, polypeptide A3
 2572
 0.17
chr2_181319204_181319455 0.29 Rtel1
 regulator of telomere elongation helicase 1
 410
 0.71
chr14_11774748_11774923 0.28 Gm48602
 predicted gene, 48602
 6892
 0.28
chr18_31921125_31921293 0.28 Lims2
 LIM and senescent cell antigen like domains 2
 1081
 0.41
chr17_10417375_10417580 0.28 A230009B12Rik
 RIKEN cDNA A230009B12 gene
 38739
 0.18
chr4_86661560_86661711 0.28 Plin2
 perilipin 2
 2487
 0.26
chr3_133369683_133370155 0.27 Ppa2
 pyrophosphatase (inorganic) 2
 2495
 0.32
chr7_119940980_119941134 0.27 Lyrm1
 LYR motif containing 1
 4099
 0.18
chr15_75118840_75119002 0.27 Ly6c2
 lymphocyte antigen 6 complex, locus C2
 6951
 0.12
chr1_136140658_136140838 0.27 Kif21b
 kinesin family member 21B
 9294
 0.11
chr17_34972548_34972711 0.27 Hspa1l
 heat shock protein 1-like
 74
 0.8
chr12_70011836_70012241 0.27 Nin
 ninein
 14789
 0.11
chr17_80171624_80171842 0.27 Galm
 galactose mutarotase
 26581
 0.12
chr7_143757599_143757799 0.27 Osbpl5
 oxysterol binding protein-like 5
 714
 0.53
chr14_33810284_33810447 0.27 4930503F20Rik
 RIKEN cDNA 4930503F20 gene
 918
 0.56
chr10_50881617_50881776 0.26 Sim1
 single-minded family bHLH transcription factor 1
 13058
 0.25
chr3_98742508_98742984 0.26 Hsd3b3
 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
 10719
 0.13
chr4_107302924_107303085 0.26 Dio1
 deiodinase, iodothyronine, type I
 4062
 0.14
chr10_68134623_68135230 0.26 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 1700
 0.47
chr1_91258114_91258381 0.26 Ube2f
 ubiquitin-conjugating enzyme E2F (putative)
 6340
 0.15
chr6_38786978_38787346 0.25 Hipk2
 homeodomain interacting protein kinase 2
 31184
 0.19
chr2_11568118_11568271 0.25 Pfkfb3
 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
 14117
 0.12
chr6_3620394_3620634 0.25 Vps50
 VPS50 EARP/GARPII complex subunit
 26496
 0.17
chr4_92376164_92376339 0.25 Gm12638
 predicted gene 12638
 2903
 0.4
chr4_137765730_137766012 0.25 Alpl
 alkaline phosphatase, liver/bone/kidney
 604
 0.75
chr6_28608968_28609322 0.25 Gm37978
 predicted gene, 37978
 41073
 0.13
chr14_73776184_73776350 0.24 Gm24540
 predicted gene, 24540
 8299
 0.18
chr16_26588376_26588753 0.24 Il1rap
 interleukin 1 receptor accessory protein
 6807
 0.28
chr2_160665583_160665820 0.24 Top1
 topoisomerase (DNA) I
 4432
 0.21
chr2_104583567_104583832 0.24 Gm13885
 predicted gene 13885
 82
 0.95
chr11_3136445_3136953 0.24 Sfi1
 Sfi1 homolog, spindle assembly associated (yeast)
 692
 0.58
chr4_102850868_102851049 0.24 Sgip1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 19606
 0.23
chr3_104424019_104424377 0.24 Gm9273
 predicted gene 9273
 5871
 0.15
chr1_176797454_176797628 0.24 Cep170
 centrosomal protein 170
 3922
 0.14
chr5_8164154_8164307 0.23 Gm21759
 predicted gene, 21759
 15406
 0.17
chr11_110101538_110102129 0.23 Abca8a
 ATP-binding cassette, sub-family A (ABC1), member 8a
 5855
 0.27
chr8_13158770_13158987 0.23 Lamp1
 lysosomal-associated membrane protein 1
 283
 0.82
chr9_122865001_122865302 0.23 Zfp445
 zinc finger protein 445
 783
 0.46
chr4_114987039_114987534 0.23 Cmpk1
 cytidine monophosphate (UMP-CMP) kinase 1
 45
 0.97
chr7_115795074_115795225 0.23 Sox6
 SRY (sex determining region Y)-box 6
 29561
 0.24
chr17_65536272_65536447 0.23 Tmem232
 transmembrane protein 232
 4385
 0.17
chr4_53539908_53540113 0.23 Slc44a1
 solute carrier family 44, member 1
 4398
 0.24
chr10_3281127_3281278 0.22 H60c
 histocompatibility 60c
 13431
 0.18
chr5_21737297_21737945 0.22 Pmpcb
 peptidase (mitochondrial processing) beta
 415
 0.77
chr17_86528291_86528457 0.22 Gm10309
 predicted gene 10309
 23142
 0.2
chr15_103273039_103273393 0.22 Copz1
 coatomer protein complex, subunit zeta 1
 304
 0.8
chr11_54355641_54355819 0.22 Gm12224
 predicted gene 12224
 2251
 0.21
chr9_57312626_57312793 0.22 Gm18996
 predicted gene, 18996
 16706
 0.14
chr15_6209633_6209839 0.22 Gm23139
 predicted gene, 23139
 58388
 0.13
chr13_41218870_41219122 0.21 Elovl2
 elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2
 1166
 0.36
chr15_50267936_50268109 0.21 Gm49198
 predicted gene, 49198
 18876
 0.3
chr19_24153611_24153973 0.21 Gm50308
 predicted gene, 50308
 278
 0.9
chr5_87870211_87870412 0.21 Odam
 odontogenic, ameloblast asssociated
 14718
 0.1
chr9_54864660_54864839 0.21 Ireb2
 iron responsive element binding protein 2
 960
 0.53
chr1_36546704_36546886 0.21 Ankrd39
 ankyrin repeat domain 39
 424
 0.66
chr9_48787148_48787352 0.21 Zbtb16
 zinc finger and BTB domain containing 16
 48695
 0.15
chr9_69285383_69285592 0.20 Rora
 RAR-related orphan receptor alpha
 4195
 0.29
chr10_98666150_98666367 0.20 Gm5427
 predicted gene 5427
 33452
 0.22
chr9_44391308_44391459 0.20 Hyou1
 hypoxia up-regulated 1
 722
 0.32
chr1_59176886_59177061 0.20 Mpp4
 membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)
 13584
 0.12
chr12_72490399_72490568 0.20 Lrrc9
 leucine rich repeat containing 9
 5184
 0.21
chr12_51195911_51196081 0.20 Gm7172
 predicted gene 7172
 61294
 0.12
chr15_67343180_67343342 0.20 1700012I11Rik
 RIKEN cDNA 1700012I11 gene
 116492
 0.06
chr1_130741555_130741763 0.20 Gm28857
 predicted gene 28857
 332
 0.74
chr18_44525317_44525773 0.20 Mcc
 mutated in colorectal cancers
 6029
 0.29
chr5_92725821_92725972 0.20 Gm20500
 predicted gene 20500
 10309
 0.19
chr13_74019384_74019615 0.20 Gm6263
 predicted gene 6263
 635
 0.58
chr2_135825531_135825682 0.20 Gm14210
 predicted gene 14210
 12679
 0.22
chr6_28734300_28734519 0.19 Snd1
 staphylococcal nuclease and tudor domain containing 1
 28689
 0.19
chr5_8813928_8814079 0.19 Abcb1b
 ATP-binding cassette, sub-family B (MDR/TAP), member 1B
 11287
 0.15
chr13_80940527_80940956 0.19 5430425K12Rik
 RIKEN cDNA 5430425K12 gene
 318
 0.85
chr5_54086048_54086199 0.19 Gm15820
 predicted gene 15820
 8957
 0.23
chr2_50492868_50493026 0.19 Gm13488
 predicted gene 13488
 28913
 0.16
chr10_95552026_95552177 0.19 Mir3058
 microRNA 3058
 7220
 0.13
chr4_138967634_138968170 0.19 Rnf186
 ring finger protein 186
 790
 0.57
chr3_31045033_31045199 0.19 Mir7008
 microRNA 7008
 6150
 0.18
chr5_8947059_8947215 0.19 Abcb4
 ATP-binding cassette, sub-family B (MDR/TAP), member 4
 11415
 0.13
chr3_118629791_118629942 0.19 Dpyd
 dihydropyrimidine dehydrogenase
 67680
 0.11
chr16_43365711_43365882 0.19 Zbtb20
 zinc finger and BTB domain containing 20
 1592
 0.33
chr14_100234504_100234883 0.19 Gm16260
 predicted gene 16260
 15207
 0.18
chr14_58072759_58072910 0.18 Fgf9
 fibroblast growth factor 9
 148
 0.96
chr13_18123081_18123244 0.18 4930448F12Rik
 RIKEN cDNA 4930448F12 gene
 22960
 0.14
chr11_102852004_102852179 0.18 Eftud2
 elongation factor Tu GTP binding domain containing 2
 4112
 0.12
chr5_97834854_97835170 0.18 Antxr2
 anthrax toxin receptor 2
 161083
 0.03
chr9_115342664_115342815 0.18 Stt3b
 STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)
 32318
 0.11
chr1_164411158_164411348 0.18 Gm37411
 predicted gene, 37411
 13460
 0.15
chr17_10408684_10408855 0.17 A230009B12Rik
 RIKEN cDNA A230009B12 gene
 47447
 0.15
chr9_69317827_69317978 0.17 Rora
 RAR-related orphan receptor alpha
 28220
 0.17
chr1_9739980_9740131 0.17 1700034P13Rik
 RIKEN cDNA 1700034P13 gene
 7593
 0.15
chr17_51016495_51016646 0.17 Tbc1d5
 TBC1 domain family, member 5
 31944
 0.23
chr12_55495363_55495542 0.17 Gm36634
 predicted gene, 36634
 2269
 0.26
chr2_6864030_6864201 0.17 Celf2
 CUGBP, Elav-like family member 2
 7857
 0.21
chr11_16780614_16780813 0.17 Egfr
 epidermal growth factor receptor
 28483
 0.16
chr6_141960851_141961033 0.17 Slco1a1
 solute carrier organic anion transporter family, member 1a1
 13980
 0.21
chr8_82402195_82403147 0.17 Il15
 interleukin 15
 101
 0.98
chr6_47533245_47533448 0.17 Ezh2
 enhancer of zeste 2 polycomb repressive complex 2 subunit
 1230
 0.46
chr10_94562316_94562469 0.17 Tmcc3
 transmembrane and coiled coil domains 3
 11520
 0.17
chr18_68294635_68294920 0.17 Fam210a
 family with sequence similarity 210, member A
 5425
 0.17
chr9_65294825_65295003 0.16 Clpx
 caseinolytic mitochondrial matrix peptidase chaperone subunit
 582
 0.58
chr14_21576956_21577113 0.16 Kat6b
 K(lysine) acetyltransferase 6B
 45508
 0.15
chr9_65675680_65676009 0.16 Oaz2
 ornithine decarboxylase antizyme 2
 704
 0.64
chr7_115674256_115674428 0.16 Sox6
 SRY (sex determining region Y)-box 6
 11977
 0.31
chr5_109796686_109796837 0.16 A430073D23Rik
 RIKEN cDNA A430073D23 gene
 463
 0.79
chr5_89454709_89454919 0.16 Gc
 vitamin D binding protein
 3084
 0.3
chr1_182593671_182593859 0.16 Capn8
 calpain 8
 28727
 0.15
chr7_12949231_12949439 0.16 1810019N24Rik
 RIKEN cDNA 1810019N24 gene
 731
 0.41
chr11_60540124_60540296 0.16 Alkbh5
 alkB homolog 5, RNA demethylase
 2232
 0.16
chr1_45924034_45924550 0.16 Slc40a1
 solute carrier family 40 (iron-regulated transporter), member 1
 970
 0.47
chr1_161037769_161037920 0.16 Gas5
 growth arrest specific 5
 63
 0.48
chr5_28056784_28057184 0.16 Gm26608
 predicted gene, 26608
 1525
 0.35
chr19_47580710_47580962 0.16 Slk
 STE20-like kinase
 817
 0.55
chr16_26697784_26698094 0.16 Il1rap
 interleukin 1 receptor accessory protein
 24495
 0.23
chr14_25783005_25783218 0.16 Zcchc24
 zinc finger, CCHC domain containing 24
 14072
 0.14
chr11_55027978_55028300 0.16 Anxa6
 annexin A6
 5276
 0.18
chr2_75670305_75670456 0.15 Hnrnpa3
 heterogeneous nuclear ribonucleoprotein A3
 7891
 0.13
chr16_47878967_47879125 0.15 Gm7275
 predicted gene 7275
 193951
 0.03
chr7_110538178_110538390 0.15 Gm10087
 predicted gene 10087
 11492
 0.18
chr8_67497857_67498024 0.15 Nat2
 N-acetyltransferase 2 (arylamine N-acetyltransferase)
 2992
 0.21
chr3_102676819_102676970 0.15 Gm19202
 predicted gene, 19202
 9823
 0.14
chr11_104407376_104407606 0.15 Gm47315
 predicted gene, 47315
 17809
 0.17
chr3_121439715_121440163 0.15 Cnn3
 calponin 3, acidic
 9827
 0.14
chr10_61606149_61606306 0.15 Gm28447
 predicted gene 28447
 4847
 0.14
chr15_36421245_36421431 0.15 Gm49224
 predicted gene, 49224
 15353
 0.14
chr6_114648264_114648681 0.15 Atg7
 autophagy related 7
 374
 0.9
chr1_86498300_86498465 0.15 Rpl30-ps6
 ribosomal protein L30, pseudogene 6
 24723
 0.11
chr1_34239606_34239757 0.15 Dst
 dystonin
 3085
 0.23
chr3_149224186_149224562 0.15 Gm10287
 predicted gene 10287
 1371
 0.47
chr1_67235446_67235799 0.15 Gm15668
 predicted gene 15668
 13578
 0.22
chr2_84649728_84650026 0.15 Ctnnd1
 catenin (cadherin associated protein), delta 1
 397
 0.71
chr12_84654027_84654189 0.15 Vrtn
 vertebrae development associated
 11212
 0.15
chr9_121799539_121799690 0.15 Hhatl
 hedgehog acyltransferase-like
 7107
 0.09
chr13_43445030_43445211 0.15 Ranbp9
 RAN binding protein 9
 14324
 0.13
chr8_81806939_81807093 0.14 Gm17169
 predicted gene 17169
 16108
 0.2
chr8_46887805_46887956 0.14 Gm45481
 predicted gene 45481
 53968
 0.1
chr11_16895683_16895855 0.14 Egfr
 epidermal growth factor receptor
 9416
 0.2
chr1_60545486_60545637 0.14 Gm11576
 predicted gene 11576
 8541
 0.14

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.1 0.2 GO:0009139 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.2 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.1 0.2 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.1 0.3 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.2 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0034727 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:1902488 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0032819 positive regulation of natural killer cell proliferation(GO:0032819)
0.0 0.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.1 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.1 GO:0014834 skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0 0.1 GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:1902988 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.2 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:1902966 regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0 0.1 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.0 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0 0.0 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.1 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.2 GO:0006878 cellular copper ion homeostasis(GO:0006878)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0046512 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.2 GO:2000188 regulation of cholesterol homeostasis(GO:2000188)
0.0 0.1 GO:0031665 negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0 0.0 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.0 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.0 GO:1903059 regulation of protein lipidation(GO:1903059)
0.0 0.2 GO:0042026 protein refolding(GO:0042026)
0.0 0.1 GO:2000370 positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.0 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0010875 positive regulation of cholesterol efflux(GO:0010875)
0.0 0.0 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.0 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.0 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0032010 phagolysosome(GO:0032010)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.2 GO:0045275 mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.0 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.0 GO:0036449 microtubule minus-end(GO:0036449)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0050145 nucleoside phosphate kinase activity(GO:0050145)
0.1 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0070548 L-glutamine aminotransferase activity(GO:0070548)
0.0 0.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.2 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.1 GO:0035276 ethanol binding(GO:0035276)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.0 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139)
0.0 0.1 GO:0070878 primary miRNA binding(GO:0070878)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0000309 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.2 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.0 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.0 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.0 0.1 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.0 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0097001 ceramide binding(GO:0097001)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.3 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.2 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.0 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC