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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Sox1

Z-value: 0.83

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Transcription factors associated with Sox1

Gene Symbol	Gene ID	Gene Info
Sox1 Ensembl NCBI MGI UniProt	ENSMUSG00000096014.1	Sox1

Activity of the Sox1 motif across conditions

Conditions sorted by the z-value of the Sox1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr19_16179580_16179731	1.09	E030024N20Rik	RIKEN cDNA E030024N20 gene	14850	0.2
chr7_98351056_98351207	0.98	Tsku	tsukushi, small leucine rich proteoglycan	8948	0.17
chr19_29520625_29520778	0.88	A930007I19Rik	RIKEN cDNA A930007I19 gene	269	0.89
chr10_77011600_77011778	0.79	Gm10787	predicted gene 10787	306	0.84
chr4_101352284_101352479	0.75	0610043K17Rik	RIKEN cDNA 0610043K17 gene	1402	0.26
chr12_80010993_80011167	0.62	Gm8275	predicted gene 8275	31229	0.14
chr5_86918463_86918614	0.61	Gm25211	predicted gene, 25211	2216	0.17
chr9_31209643_31210005	0.61	Aplp2	amyloid beta (A4) precursor-like protein 2	1963	0.34
chr1_85325110_85325261	0.60	Gm16025	predicted gene 16025	1544	0.27
chr19_44401346_44401497	0.60	Scd1	stearoyl-Coenzyme A desaturase 1	5269	0.16
chr3_31075182_31075333	0.52	Skil	SKI-like	19801	0.16
chr11_90184166_90184514	0.51	n-R5s72	nuclear encoded rRNA 5S 72	787	0.57
chr14_9492003_9492160	0.51	Gm48371	predicted gene, 48371	22526	0.26
chr3_112120839_112120990	0.51	Gm25519	predicted gene, 25519	78127	0.1
chr2_113534474_113534796	0.49	Gm13964	predicted gene 13964	30601	0.17
chr1_162892544_162892705	0.46	Fmo2	flavin containing monooxygenase 2	5860	0.19
chr2_71212098_71212533	0.45	Dync1i2	dynein cytoplasmic 1 intermediate chain 2	311	0.92
chr11_60205641_60205948	0.43	Srebf1	sterol regulatory element binding transcription factor 1	318	0.81
chr19_16029083_16029234	0.43	Rpl37-ps1	ribosomal protein 37, pseudogene 1	3707	0.24
chr3_88173707_88173903	0.43	1700113A16Rik	RIKEN cDNA 1700113A16 gene	3887	0.11
chr4_44976139_44976290	0.42	Gm12679	predicted gene 12679	2105	0.19
chr5_145454830_145455000	0.42	Cyp3a16	cytochrome P450, family 3, subfamily a, polypeptide 16	14808	0.16
chr1_74751129_74751319	0.41	Prkag3	protein kinase, AMP-activated, gamma 3 non-catalytic subunit	2003	0.21
chr9_103209178_103209657	0.41	Trf	transferrin	2589	0.24
chr12_40564154_40564324	0.40	Dock4	dedicator of cytokinesis 4	117903	0.06
chr1_151339242_151339404	0.40	Gm10138	predicted gene 10138	4759	0.16
chr7_68140395_68140567	0.40	Igf1r	insulin-like growth factor I receptor	8109	0.26
chr12_32764273_32764609	0.40	Gm18726	predicted gene, 18726	54280	0.11
chr2_31514522_31514710	0.39	Ass1	argininosuccinate synthetase 1	3874	0.21
chr7_67655501_67655709	0.39	Ttc23	tetratricopeptide repeat domain 23	158	0.93
chr5_66035556_66035796	0.39	Rbm47	RNA binding motif protein 47	18876	0.11
chr18_61798684_61798836	0.38	Afap1l1	actin filament associated protein 1-like 1	12058	0.18
chr3_94699549_94699901	0.38	Selenbp2	selenium binding protein 2	6066	0.12
chr3_116302483_116302634	0.38	Gm29151	predicted gene 29151	47545	0.11
chr5_140118402_140118733	0.38	Mad1l1	MAD1 mitotic arrest deficient 1-like 1	3101	0.21
chr6_149057714_149057872	0.37	Gm49058	predicted gene, 49058	3945	0.12
chr5_49060180_49060366	0.37	Gm43047	predicted gene 43047	9730	0.1
chr4_60245923_60246074	0.37	Mup-ps3	major urinary protein, pseudogene 3	8653	0.19
chr8_45630130_45630742	0.37	Sorbs2	sorbin and SH3 domain containing 2	2235	0.3
chr17_48484838_48484989	0.36	Unc5cl	unc-5 family C-terminal like	22509	0.13
chr4_59006708_59006875	0.36	Gm20503	predicted gene 20503	3581	0.16
chr9_35209800_35209963	0.35	Foxred1	FAD-dependent oxidoreductase domain containing 1	1016	0.31
chr4_152264194_152264355	0.35	Gpr153	G protein-coupled receptor 153	9958	0.12
chr5_117165254_117165405	0.35	n-R5s174	nuclear encoded rRNA 5S 174	31226	0.11
chr19_10904836_10905155	0.35	Prpf19	pre-mRNA processing factor 19	4713	0.11
chr4_61167643_61167862	0.34	Mup-ps9	major urinary protein, pseudogene 9	4689	0.27
chr1_160781397_160781614	0.34	Rabgap1l	RAB GTPase activating protein 1-like	11433	0.12
chr9_102354784_102354966	0.34	Ephb1	Eph receptor B1	182	0.95
chr4_53227508_53227716	0.34	4930412L05Rik	RIKEN cDNA 4930412L05 gene	9755	0.17
chr13_3634828_3634979	0.34	Asb13	ankyrin repeat and SOCS box-containing 13	804	0.58
chr4_61248201_61248394	0.33	Mup-ps10	major urinary protein, pseudogene 10	4720	0.21
chr13_96648408_96648591	0.33	Hmgcr	3-hydroxy-3-methylglutaryl-Coenzyme A reductase	4304	0.17
chr17_86393949_86394100	0.32	Prkce	protein kinase C, epsilon	96538	0.07
chr10_57848460_57848621	0.32	Smpdl3a	sphingomyelin phosphodiesterase, acid-like 3A	53972	0.13
chr2_31515291_31515653	0.32	Ass1	argininosuccinate synthetase 1	3018	0.23
chr15_65337961_65338116	0.31	Gm49242	predicted gene, 49242	137476	0.05
chr2_26663667_26663830	0.31	Lcn4	lipocalin 4	7534	0.11
chr3_95885104_95885275	0.31	Ciart	circadian associated repressor of transcription	2938	0.1
chr2_163568842_163568993	0.31	Hnf4a	hepatic nuclear factor 4, alpha	18834	0.12
chr4_97905915_97906126	0.30	Nfia	nuclear factor I/A	5013	0.32
chr7_16598127_16598332	0.30	Gm29443	predicted gene 29443	15595	0.09
chr10_124590350_124590536	0.30	4930503E24Rik	RIKEN cDNA 4930503E24 gene	67005	0.14
chr5_89493650_89493829	0.30	Gm6366	predicted gene 6366	6238	0.21
chr1_52004207_52004365	0.29	Stat4	signal transducer and activator of transcription 4	3957	0.2
chr5_87334492_87334755	0.29	Ugt2a3	UDP glucuronosyltransferase 2 family, polypeptide A3	2572	0.17
chr2_181319204_181319455	0.29	Rtel1	regulator of telomere elongation helicase 1	410	0.71
chr14_11774748_11774923	0.28	Gm48602	predicted gene, 48602	6892	0.28
chr18_31921125_31921293	0.28	Lims2	LIM and senescent cell antigen like domains 2	1081	0.41
chr17_10417375_10417580	0.28	A230009B12Rik	RIKEN cDNA A230009B12 gene	38739	0.18
chr4_86661560_86661711	0.28	Plin2	perilipin 2	2487	0.26
chr3_133369683_133370155	0.27	Ppa2	pyrophosphatase (inorganic) 2	2495	0.32
chr7_119940980_119941134	0.27	Lyrm1	LYR motif containing 1	4099	0.18
chr15_75118840_75119002	0.27	Ly6c2	lymphocyte antigen 6 complex, locus C2	6951	0.12
chr1_136140658_136140838	0.27	Kif21b	kinesin family member 21B	9294	0.11
chr17_34972548_34972711	0.27	Hspa1l	heat shock protein 1-like	74	0.8
chr12_70011836_70012241	0.27	Nin	ninein	14789	0.11
chr17_80171624_80171842	0.27	Galm	galactose mutarotase	26581	0.12
chr7_143757599_143757799	0.27	Osbpl5	oxysterol binding protein-like 5	714	0.53
chr14_33810284_33810447	0.27	4930503F20Rik	RIKEN cDNA 4930503F20 gene	918	0.56
chr10_50881617_50881776	0.26	Sim1	single-minded family bHLH transcription factor 1	13058	0.25
chr3_98742508_98742984	0.26	Hsd3b3	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3	10719	0.13
chr4_107302924_107303085	0.26	Dio1	deiodinase, iodothyronine, type I	4062	0.14
chr10_68134623_68135230	0.26	Arid5b	AT rich interactive domain 5B (MRF1-like)	1700	0.47
chr1_91258114_91258381	0.26	Ube2f	ubiquitin-conjugating enzyme E2F (putative)	6340	0.15
chr6_38786978_38787346	0.25	Hipk2	homeodomain interacting protein kinase 2	31184	0.19
chr2_11568118_11568271	0.25	Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	14117	0.12
chr6_3620394_3620634	0.25	Vps50	VPS50 EARP/GARPII complex subunit	26496	0.17
chr4_92376164_92376339	0.25	Gm12638	predicted gene 12638	2903	0.4
chr4_137765730_137766012	0.25	Alpl	alkaline phosphatase, liver/bone/kidney	604	0.75
chr6_28608968_28609322	0.25	Gm37978	predicted gene, 37978	41073	0.13
chr14_73776184_73776350	0.24	Gm24540	predicted gene, 24540	8299	0.18
chr16_26588376_26588753	0.24	Il1rap	interleukin 1 receptor accessory protein	6807	0.28
chr2_160665583_160665820	0.24	Top1	topoisomerase (DNA) I	4432	0.21
chr2_104583567_104583832	0.24	Gm13885	predicted gene 13885	82	0.95
chr11_3136445_3136953	0.24	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	692	0.58
chr4_102850868_102851049	0.24	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	19606	0.23
chr3_104424019_104424377	0.24	Gm9273	predicted gene 9273	5871	0.15
chr1_176797454_176797628	0.24	Cep170	centrosomal protein 170	3922	0.14
chr5_8164154_8164307	0.23	Gm21759	predicted gene, 21759	15406	0.17
chr11_110101538_110102129	0.23	Abca8a	ATP-binding cassette, sub-family A (ABC1), member 8a	5855	0.27
chr8_13158770_13158987	0.23	Lamp1	lysosomal-associated membrane protein 1	283	0.82
chr9_122865001_122865302	0.23	Zfp445	zinc finger protein 445	783	0.46
chr4_114987039_114987534	0.23	Cmpk1	cytidine monophosphate (UMP-CMP) kinase 1	45	0.97
chr7_115795074_115795225	0.23	Sox6	SRY (sex determining region Y)-box 6	29561	0.24
chr17_65536272_65536447	0.23	Tmem232	transmembrane protein 232	4385	0.17
chr4_53539908_53540113	0.23	Slc44a1	solute carrier family 44, member 1	4398	0.24
chr10_3281127_3281278	0.22	H60c	histocompatibility 60c	13431	0.18
chr5_21737297_21737945	0.22	Pmpcb	peptidase (mitochondrial processing) beta	415	0.77
chr17_86528291_86528457	0.22	Gm10309	predicted gene 10309	23142	0.2
chr15_103273039_103273393	0.22	Copz1	coatomer protein complex, subunit zeta 1	304	0.8
chr11_54355641_54355819	0.22	Gm12224	predicted gene 12224	2251	0.21
chr9_57312626_57312793	0.22	Gm18996	predicted gene, 18996	16706	0.14
chr15_6209633_6209839	0.22	Gm23139	predicted gene, 23139	58388	0.13
chr13_41218870_41219122	0.21	Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	1166	0.36
chr15_50267936_50268109	0.21	Gm49198	predicted gene, 49198	18876	0.3
chr19_24153611_24153973	0.21	Gm50308	predicted gene, 50308	278	0.9
chr5_87870211_87870412	0.21	Odam	odontogenic, ameloblast asssociated	14718	0.1
chr9_54864660_54864839	0.21	Ireb2	iron responsive element binding protein 2	960	0.53
chr1_36546704_36546886	0.21	Ankrd39	ankyrin repeat domain 39	424	0.66
chr9_48787148_48787352	0.21	Zbtb16	zinc finger and BTB domain containing 16	48695	0.15
chr9_69285383_69285592	0.20	Rora	RAR-related orphan receptor alpha	4195	0.29
chr10_98666150_98666367	0.20	Gm5427	predicted gene 5427	33452	0.22
chr9_44391308_44391459	0.20	Hyou1	hypoxia up-regulated 1	722	0.32
chr1_59176886_59177061	0.20	Mpp4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)	13584	0.12
chr12_72490399_72490568	0.20	Lrrc9	leucine rich repeat containing 9	5184	0.21
chr12_51195911_51196081	0.20	Gm7172	predicted gene 7172	61294	0.12
chr15_67343180_67343342	0.20	1700012I11Rik	RIKEN cDNA 1700012I11 gene	116492	0.06
chr1_130741555_130741763	0.20	Gm28857	predicted gene 28857	332	0.74
chr18_44525317_44525773	0.20	Mcc	mutated in colorectal cancers	6029	0.29
chr5_92725821_92725972	0.20	Gm20500	predicted gene 20500	10309	0.19
chr13_74019384_74019615	0.20	Gm6263	predicted gene 6263	635	0.58
chr2_135825531_135825682	0.20	Gm14210	predicted gene 14210	12679	0.22
chr6_28734300_28734519	0.19	Snd1	staphylococcal nuclease and tudor domain containing 1	28689	0.19
chr5_8813928_8814079	0.19	Abcb1b	ATP-binding cassette, sub-family B (MDR/TAP), member 1B	11287	0.15
chr13_80940527_80940956	0.19	5430425K12Rik	RIKEN cDNA 5430425K12 gene	318	0.85
chr5_54086048_54086199	0.19	Gm15820	predicted gene 15820	8957	0.23
chr2_50492868_50493026	0.19	Gm13488	predicted gene 13488	28913	0.16
chr10_95552026_95552177	0.19	Mir3058	microRNA 3058	7220	0.13
chr4_138967634_138968170	0.19	Rnf186	ring finger protein 186	790	0.57
chr3_31045033_31045199	0.19	Mir7008	microRNA 7008	6150	0.18
chr5_8947059_8947215	0.19	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	11415	0.13
chr3_118629791_118629942	0.19	Dpyd	dihydropyrimidine dehydrogenase	67680	0.11
chr16_43365711_43365882	0.19	Zbtb20	zinc finger and BTB domain containing 20	1592	0.33
chr14_100234504_100234883	0.19	Gm16260	predicted gene 16260	15207	0.18
chr14_58072759_58072910	0.18	Fgf9	fibroblast growth factor 9	148	0.96
chr13_18123081_18123244	0.18	4930448F12Rik	RIKEN cDNA 4930448F12 gene	22960	0.14
chr11_102852004_102852179	0.18	Eftud2	elongation factor Tu GTP binding domain containing 2	4112	0.12
chr5_97834854_97835170	0.18	Antxr2	anthrax toxin receptor 2	161083	0.03
chr9_115342664_115342815	0.18	Stt3b	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae)	32318	0.11
chr1_164411158_164411348	0.18	Gm37411	predicted gene, 37411	13460	0.15
chr17_10408684_10408855	0.17	A230009B12Rik	RIKEN cDNA A230009B12 gene	47447	0.15
chr9_69317827_69317978	0.17	Rora	RAR-related orphan receptor alpha	28220	0.17
chr1_9739980_9740131	0.17	1700034P13Rik	RIKEN cDNA 1700034P13 gene	7593	0.15
chr17_51016495_51016646	0.17	Tbc1d5	TBC1 domain family, member 5	31944	0.23
chr12_55495363_55495542	0.17	Gm36634	predicted gene, 36634	2269	0.26
chr2_6864030_6864201	0.17	Celf2	CUGBP, Elav-like family member 2	7857	0.21
chr11_16780614_16780813	0.17	Egfr	epidermal growth factor receptor	28483	0.16
chr6_141960851_141961033	0.17	Slco1a1	solute carrier organic anion transporter family, member 1a1	13980	0.21
chr8_82402195_82403147	0.17	Il15	interleukin 15	101	0.98
chr6_47533245_47533448	0.17	Ezh2	enhancer of zeste 2 polycomb repressive complex 2 subunit	1230	0.46
chr10_94562316_94562469	0.17	Tmcc3	transmembrane and coiled coil domains 3	11520	0.17
chr18_68294635_68294920	0.17	Fam210a	family with sequence similarity 210, member A	5425	0.17
chr9_65294825_65295003	0.16	Clpx	caseinolytic mitochondrial matrix peptidase chaperone subunit	582	0.58
chr14_21576956_21577113	0.16	Kat6b	K(lysine) acetyltransferase 6B	45508	0.15
chr9_65675680_65676009	0.16	Oaz2	ornithine decarboxylase antizyme 2	704	0.64
chr7_115674256_115674428	0.16	Sox6	SRY (sex determining region Y)-box 6	11977	0.31
chr5_109796686_109796837	0.16	A430073D23Rik	RIKEN cDNA A430073D23 gene	463	0.79
chr5_89454709_89454919	0.16	Gc	vitamin D binding protein	3084	0.3
chr1_182593671_182593859	0.16	Capn8	calpain 8	28727	0.15
chr7_12949231_12949439	0.16	1810019N24Rik	RIKEN cDNA 1810019N24 gene	731	0.41
chr11_60540124_60540296	0.16	Alkbh5	alkB homolog 5, RNA demethylase	2232	0.16
chr1_45924034_45924550	0.16	Slc40a1	solute carrier family 40 (iron-regulated transporter), member 1	970	0.47
chr1_161037769_161037920	0.16	Gas5	growth arrest specific 5	63	0.48
chr5_28056784_28057184	0.16	Gm26608	predicted gene, 26608	1525	0.35
chr19_47580710_47580962	0.16	Slk	STE20-like kinase	817	0.55
chr16_26697784_26698094	0.16	Il1rap	interleukin 1 receptor accessory protein	24495	0.23
chr14_25783005_25783218	0.16	Zcchc24	zinc finger, CCHC domain containing 24	14072	0.14
chr11_55027978_55028300	0.16	Anxa6	annexin A6	5276	0.18
chr2_75670305_75670456	0.15	Hnrnpa3	heterogeneous nuclear ribonucleoprotein A3	7891	0.13
chr16_47878967_47879125	0.15	Gm7275	predicted gene 7275	193951	0.03
chr7_110538178_110538390	0.15	Gm10087	predicted gene 10087	11492	0.18
chr8_67497857_67498024	0.15	Nat2	N-acetyltransferase 2 (arylamine N-acetyltransferase)	2992	0.21
chr3_102676819_102676970	0.15	Gm19202	predicted gene, 19202	9823	0.14
chr11_104407376_104407606	0.15	Gm47315	predicted gene, 47315	17809	0.17
chr3_121439715_121440163	0.15	Cnn3	calponin 3, acidic	9827	0.14
chr10_61606149_61606306	0.15	Gm28447	predicted gene 28447	4847	0.14
chr15_36421245_36421431	0.15	Gm49224	predicted gene, 49224	15353	0.14
chr6_114648264_114648681	0.15	Atg7	autophagy related 7	374	0.9
chr1_86498300_86498465	0.15	Rpl30-ps6	ribosomal protein L30, pseudogene 6	24723	0.11
chr1_34239606_34239757	0.15	Dst	dystonin	3085	0.23
chr3_149224186_149224562	0.15	Gm10287	predicted gene 10287	1371	0.47
chr1_67235446_67235799	0.15	Gm15668	predicted gene 15668	13578	0.22
chr2_84649728_84650026	0.15	Ctnnd1	catenin (cadherin associated protein), delta 1	397	0.71
chr12_84654027_84654189	0.15	Vrtn	vertebrae development associated	11212	0.15
chr9_121799539_121799690	0.15	Hhatl	hedgehog acyltransferase-like	7107	0.09
chr13_43445030_43445211	0.15	Ranbp9	RAN binding protein 9	14324	0.13
chr8_81806939_81807093	0.14	Gm17169	predicted gene 17169	16108	0.2
chr8_46887805_46887956	0.14	Gm45481	predicted gene 45481	53968	0.1
chr11_16895683_16895855	0.14	Egfr	epidermal growth factor receptor	9416	0.2
chr1_60545486_60545637	0.14	Gm11576	predicted gene 11576	8541	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.2	GO:0009139	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1	0.2	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.1	0.2	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.1	0.3	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.1	0.2	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.0	0.1	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0	0.1	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.2	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.2	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0014834	skeletal muscle satellite cell maintenance involved in skeletal muscle regeneration(GO:0014834)
0.0	0.1	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.2	GO:0070995	NADPH oxidation(GO:0070995)
0.0	0.2	GO:0045634	regulation of melanocyte differentiation(GO:0045634)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:1902988	neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0	0.2	GO:0048505	regulation of timing of cell differentiation(GO:0048505)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.1	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:1903297	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0	0.1	GO:0019355	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.0	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.2	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:0045046	peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0	0.2	GO:0006878	cellular copper ion homeostasis(GO:0006878)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0019695	choline metabolic process(GO:0019695)
0.0	0.1	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.2	GO:2000188	regulation of cholesterol homeostasis(GO:2000188)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.0	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.0	GO:0035627	ceramide transport(GO:0035627)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.0	GO:1903059	regulation of protein lipidation(GO:1903059)
0.0	0.2	GO:0042026	protein refolding(GO:0042026)
0.0	0.1	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0010875	positive regulation of cholesterol efflux(GO:0010875)
0.0	0.0	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.0	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.1	GO:0019367	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0	0.0	GO:0034146	toll-like receptor 5 signaling pathway(GO:0034146)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.3	GO:0032433	filopodium tip(GO:0032433)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.2	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.1	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0002199	zona pellucida receptor complex(GO:0002199)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.0	GO:1990130	Iml1 complex(GO:1990130)
0.0	0.0	GO:0036449	microtubule minus-end(GO:0036449)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.1	0.3	GO:0005005	transmembrane-ephrin receptor activity(GO:0005005)
0.1	0.2	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.1	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.1	GO:0035276	ethanol binding(GO:0035276)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.1	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.0	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0097001	ceramide binding(GO:0097001)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.4	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.3	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.3	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.2	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.2	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC