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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Sox13

Z-value: 1.05

Motif logo

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Transcription factors associated with Sox13

Gene Symbol Gene ID Gene Info
Sox13
ENSMUSG00000070643.5 SRY (sex determining region Y)-box 13

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr1_133379266_133379589Sox1360990.1519510.834.0e-02Click!
chr1_133424091_133424476Sox13940.970159-0.796.0e-02Click!
chr1_133382772_133383217Sox1325320.2209780.721.0e-01Click!
chr1_133452165_133452316Sox13278630.1586340.602.0e-01Click!
chr1_133382391_133382543Sox1330590.1972200.602.0e-01Click!

Activity of the Sox13 motif across conditions

Conditions sorted by the z-value of the Sox13 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr12_25303768_25303919 0.40 Gm36723
 predicted gene, 36723
 97
 0.92
chr19_17554976_17555127 0.26 Gm17819
 predicted gene, 17819
 137712
 0.05
chr18_43966502_43966653 0.26 Spink5
 serine peptidase inhibitor, Kazal type 5
 3342
 0.25
chr19_53781327_53781513 0.26 Rbm20
 RNA binding motif protein 20
 11888
 0.17
chr2_31519719_31520357 0.24 Ass1
 argininosuccinate synthetase 1
 1548
 0.36
chr16_24831205_24831356 0.24 Mir28a
 microRNA 28a
 3425
 0.28
chr12_16577490_16577750 0.22 Lpin1
 lipin 1
 12100
 0.23
chr3_116510337_116510525 0.22 Rtca
 RNA 3'-terminal phosphate cyclase
 2223
 0.16
chr2_59979696_59979870 0.22 Gm13574
 predicted gene 13574
 12561
 0.19
chr11_16913067_16913239 0.22 Egfr
 epidermal growth factor receptor
 7968
 0.19
chr8_40906070_40906221 0.21 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 7707
 0.17
chr1_184748659_184749028 0.21 Gm34342
 predicted gene, 34342
 11866
 0.14
chr7_44298836_44299206 0.20 Gm7238
 predicted gene 7238
 1866
 0.11
chr16_49770118_49770298 0.20 Gm15518
 predicted gene 15518
 28662
 0.19
chr19_10094218_10094369 0.20 Fads2
 fatty acid desaturase 2
 5577
 0.16
chr4_95640632_95640805 0.20 Fggy
 FGGY carbohydrate kinase domain containing
 3831
 0.31
chr11_99056309_99056460 0.20 Igfbp4
 insulin-like growth factor binding protein 4
 9073
 0.12
chr10_20504473_20504624 0.20 Gm17229
 predicted gene 17229
 13616
 0.21
chr11_16845424_16845700 0.19 Egfros
 epidermal growth factor receptor, opposite strand
 14860
 0.2
chr12_8498096_8498247 0.19 Rhob
 ras homolog family member B
 1838
 0.28
chr4_129063899_129064050 0.19 Rnf19b
 ring finger protein 19B
 5160
 0.15
chr2_35174669_35174820 0.19 Cntrl
 centriolin
 504
 0.76
chr12_24463865_24464016 0.19 Gm16372
 predicted pseudogene 16372
 29716
 0.14
chr6_149359539_149359690 0.19 Gm15784
 predicted gene 15784
 2072
 0.23
chr14_114864274_114864425 0.19 Gm49010
 predicted gene, 49010
 12161
 0.18
chr2_58737784_58737935 0.19 Gm13559
 predicted gene 13559
 2780
 0.27
chr7_93588215_93588366 0.19 Gm45039
 predicted gene 45039
 20026
 0.19
chr13_24359125_24359350 0.19 Gm11342
 predicted gene 11342
 16713
 0.12
chr19_12460408_12460573 0.18 Mpeg1
 macrophage expressed gene 1
 289
 0.84
chr3_97620995_97621148 0.18 Fmo5
 flavin containing monooxygenase 5
 7733
 0.14
chr14_88428338_88428489 0.18 Gm48930
 predicted gene, 48930
 12388
 0.18
chr19_44399803_44399962 0.18 Scd1
 stearoyl-Coenzyme A desaturase 1
 6808
 0.15
chrX_108663772_108663923 0.18 Gm379
 predicted gene 379
 608
 0.84
chr8_109996628_109997116 0.17 Tat
 tyrosine aminotransferase
 6366
 0.13
chr2_32415334_32415774 0.17 Slc25a25
 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
 1017
 0.34
chr17_50814204_50814359 0.17 Gm25177
 predicted gene, 25177
 102760
 0.07
chr4_53222171_53222454 0.17 4930412L05Rik
 RIKEN cDNA 4930412L05 gene
 4455
 0.21
chr5_102010547_102010959 0.17 Wdfy3
 WD repeat and FYVE domain containing 3
 29195
 0.16
chr9_100488481_100488638 0.17 Il20rb
 interleukin 20 receptor beta
 1771
 0.29
chr3_51238020_51238171 0.16 Noct
 nocturnin
 2111
 0.23
chr11_51598115_51598266 0.16 Phykpl
 5-phosphohydroxy-L-lysine phospholyase
 1077
 0.39
chr3_122130884_122131070 0.16 Abca4
 ATP-binding cassette, sub-family A (ABC1), member 4
 1025
 0.49
chr7_72295313_72295464 0.16 Mctp2
 multiple C2 domains, transmembrane 2
 11220
 0.29
chr9_85369091_85369242 0.16 Gm48832
 predicted gene, 48832
 21101
 0.14
chr11_90269750_90269901 0.16 Mmd
 monocyte to macrophage differentiation-associated
 20349
 0.21
chr4_83243559_83243710 0.16 Ttc39b
 tetratricopeptide repeat domain 39B
 10464
 0.2
chr2_58784544_58784695 0.16 Upp2
 uridine phosphorylase 2
 19294
 0.19
chr13_52186671_52186858 0.16 Gm48199
 predicted gene, 48199
 6353
 0.28
chr4_6270082_6270233 0.16 Cyp7a1
 cytochrome P450, family 7, subfamily a, polypeptide 1
 5474
 0.21
chr2_43522117_43522300 0.16 Gm13464
 predicted gene 13464
 2810
 0.36
chr16_85566937_85567088 0.16 Gm2541
 predicted pseudogene 2541
 13069
 0.22
chr3_158062237_158062399 0.16 Lrrc40
 leucine rich repeat containing 40
 40
 0.97
chr12_69941545_69941731 0.16 Atl1
 atlastin GTPase 1
 4539
 0.13
chr14_120368762_120368913 0.16 Mbnl2
 muscleblind like splicing factor 2
 10404
 0.23
chr18_9782900_9783271 0.16 Gm23350
 predicted gene, 23350
 19823
 0.12
chr1_67138759_67139000 0.16 Cps1
 carbamoyl-phosphate synthetase 1
 15853
 0.23
chr18_16665331_16665535 0.16 Cdh2
 cadherin 2
 4636
 0.31
chr3_81573214_81573380 0.16 Gm4857
 predicted gene 4857
 16472
 0.28
chr8_36265509_36265688 0.15 Lonrf1
 LON peptidase N-terminal domain and ring finger 1
 16082
 0.2
chr18_38888781_38888957 0.15 Gm5820
 predicted gene 5820
 3589
 0.26
chr19_33489637_33489788 0.15 Lipo5
 lipase, member O5
 16521
 0.14
chr16_45995065_45995216 0.15 Plcxd2
 phosphatidylinositol-specific phospholipase C, X domain containing 2
 15078
 0.15
chr2_58771100_58771251 0.15 Upp2
 uridine phosphorylase 2
 5850
 0.22
chr3_5396484_5396672 0.15 4930555M17Rik
 RIKEN cDNA 4930555M17 gene
 118755
 0.06
chr2_31514522_31514710 0.15 Ass1
 argininosuccinate synthetase 1
 3874
 0.21
chr11_43688020_43688171 0.15 Pwwp2a
 PWWP domain containing 2A
 3950
 0.21
chr14_116316024_116316184 0.15 Gm38045
 predicted gene, 38045
 434111
 0.01
chr10_21665548_21665708 0.15 Gm5420
 predicted gene 5420
 20783
 0.2
chrY_90734416_90734573 0.15 Mid1-ps1
 midline 1, pseudogene 1
 18563
 0.17
chr3_18152374_18152525 0.15 Gm23686
 predicted gene, 23686
 25176
 0.2
chr16_87670516_87670809 0.14 Bach1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
 28283
 0.17
chr4_150868400_150868675 0.14 Errfi1
 ERBB receptor feedback inhibitor 1
 13464
 0.13
chr1_67210897_67211317 0.14 Gm15668
 predicted gene 15668
 38093
 0.16
chr2_58779426_58779577 0.14 Upp2
 uridine phosphorylase 2
 14176
 0.2
chr5_33024447_33024632 0.14 Ywhah
 tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
 2748
 0.21
chr3_104218648_104218830 0.14 Magi3
 membrane associated guanylate kinase, WW and PDZ domain containing 3
 1364
 0.29
chr2_134853818_134853969 0.14 Gm14036
 predicted gene 14036
 49944
 0.15
chr4_62100969_62101120 0.14 Gm12910
 predicted gene 12910
 11887
 0.13
chr8_93186224_93186375 0.14 Gm45909
 predicted gene 45909
 5059
 0.15
chr2_147998244_147998434 0.14 9030622O22Rik
 RIKEN cDNA 9030622O22 gene
 22154
 0.18
chrX_169972936_169973308 0.14 Mid1
 midline 1
 237
 0.91
chr17_28420256_28420436 0.14 Fkbp5
 FK506 binding protein 5
 1819
 0.21
chr8_67497857_67498024 0.14 Nat2
 N-acetyltransferase 2 (arylamine N-acetyltransferase)
 2992
 0.21
chr7_119850861_119851025 0.14 Rexo5
 RNA exonuclease 5
 6737
 0.15
chr5_130017444_130017684 0.14 Asl
 argininosuccinate lyase
 2842
 0.16
chr11_61612422_61612587 0.14 Epn2
 epsin 2
 32817
 0.12
chr6_23115074_23115260 0.14 Aass
 aminoadipate-semialdehyde synthase
 12413
 0.16
chr7_136493976_136494136 0.14 Gm36849
 predicted gene, 36849
 140692
 0.04
chr1_67156793_67157207 0.14 Cps1
 carbamoyl-phosphate synthetase 1
 33974
 0.18
chr7_125056317_125056468 0.14 Gm45093
 predicted gene 45093
 13099
 0.23
chr12_20815638_20815951 0.14 1700030C10Rik
 RIKEN cDNA 1700030C10 gene
 15
 0.98
chr1_52465382_52465533 0.14 Nab1
 Ngfi-A binding protein 1
 1600
 0.34
chr1_186581211_186581378 0.14 A730004F24Rik
 RIKEN cDNA A730004F24 gene
 22613
 0.2
chr10_87565564_87566020 0.14 Pah
 phenylalanine hydroxylase
 19119
 0.21
chr1_24116155_24116306 0.14 Gm26607
 predicted gene, 26607
 9045
 0.17
chr11_16869435_16869808 0.14 Egfr
 epidermal growth factor receptor
 8529
 0.21
chr19_40141969_40142120 0.14 Cyp2c70
 cytochrome P450, family 2, subfamily c, polypeptide 70
 45242
 0.11
chr19_47578801_47579105 0.14 Slk
 STE20-like kinase
 725
 0.6
chr7_101084310_101084461 0.14 Fchsd2
 FCH and double SH3 domains 2
 8478
 0.17
chr13_4234942_4235096 0.14 Akr1c19
 aldo-keto reductase family 1, member C19
 1279
 0.37
chr17_55903580_55903737 0.14 Zfp959
 zinc finger protein 959
 11190
 0.1
chr11_98192679_98192909 0.13 Med1
 mediator complex subunit 1
 161
 0.92
chr2_31499430_31499808 0.13 Ass1
 argininosuccinate synthetase 1
 1107
 0.5
chr6_95118485_95118647 0.13 Kbtbd8
 kelch repeat and BTB (POZ) domain containing 8
 582
 0.58
chr6_66996154_66996403 0.13 Gm36816
 predicted gene, 36816
 12135
 0.12
chr5_38117047_38117323 0.13 Stx18
 syntaxin 18
 3724
 0.2
chr7_118572136_118572408 0.13 Tmc7
 transmembrane channel-like gene family 7
 5645
 0.16
chr10_24258031_24258221 0.13 Moxd1
 monooxygenase, DBH-like 1
 34581
 0.16
chr7_49734781_49734959 0.13 Htatip2
 HIV-1 Tat interactive protein 2
 24245
 0.19
chr19_33480626_33480777 0.13 Lipo5
 lipase, member O5
 7510
 0.16
chr18_38856050_38856246 0.13 Fgf1
 fibroblast growth factor 1
 2600
 0.31
chr5_148633016_148633167 0.13 Gm29815
 predicted gene, 29815
 19447
 0.18
chr10_55194027_55194219 0.13 Gm46190
 predicted gene, 46190
 69761
 0.14
chr5_137975596_137975772 0.13 Azgp1
 alpha-2-glycoprotein 1, zinc
 5836
 0.09
chr8_56345237_56345388 0.13 Gm45540
 predicted gene 45540
 34008
 0.18
chr13_114485155_114485339 0.13 Fst
 follistatin
 26296
 0.14
chr6_42251414_42251583 0.13 Gstk1
 glutathione S-transferase kappa 1
 5475
 0.12
chr3_51233010_51233232 0.13 Gm38357
 predicted gene, 38357
 1204
 0.38
chr3_109307549_109307748 0.13 Vav3
 vav 3 oncogene
 33005
 0.21
chr1_121297700_121297851 0.13 Gm38283
 predicted gene, 38283
 3056
 0.23
chr10_69208679_69208830 0.13 Rhobtb1
 Rho-related BTB domain containing 1
 202
 0.94
chr11_16855071_16855379 0.13 Egfr
 epidermal growth factor receptor
 22925
 0.17
chr1_73966648_73966904 0.13 Tns1
 tensin 1
 3733
 0.28
chr9_53288790_53288968 0.13 Exph5
 exophilin 5
 12791
 0.18
chr7_116331137_116331288 0.13 Rps13
 ribosomal protein S13
 1970
 0.19
chr19_6053827_6053978 0.13 AC131692.1
 mitochondrial ribosomal protein L49 (Mrpl49) pseudogene
 1764
 0.1
chr16_46841628_46841787 0.13 Gm6912
 predicted gene 6912
 232491
 0.02
chr16_24201028_24201179 0.13 Gm31814
 predicted gene, 31814
 15143
 0.2
chr3_9751433_9751584 0.13 Gm16337
 predicted gene 16337
 6099
 0.23
chr9_14045065_14045224 0.13 1700019J19Rik
 RIKEN cDNA 1700019J19 gene
 44476
 0.14
chr14_62001768_62001919 0.13 Gm47953
 predicted gene, 47953
 10476
 0.25
chr8_10899350_10899661 0.13 4833411C07Rik
 RIKEN cDNA 4833411C07 gene
 417
 0.64
chr19_10062797_10062948 0.12 Fads3
 fatty acid desaturase 3
 6620
 0.14
chr10_40511211_40511581 0.12 Gm18671
 predicted gene, 18671
 37496
 0.14
chr11_63884359_63884556 0.12 Hmgb1-ps3
 high mobility group box 1, pseudogene 3
 37639
 0.15
chr2_45463913_45464105 0.12 Gm13479
 predicted gene 13479
 106744
 0.07
chr2_58783629_58783834 0.12 Upp2
 uridine phosphorylase 2
 18406
 0.19
chrY_90810953_90811113 0.12 Gm47283
 predicted gene, 47283
 20582
 0.16
chr11_7815566_7815774 0.12 Gm27393
 predicted gene, 27393
 70835
 0.13
chr14_86309035_86309286 0.12 Gm23926
 predicted gene, 23926
 2218
 0.22
chr10_10818225_10818395 0.12 4930567K20Rik
 RIKEN cDNA 4930567K20 gene
 67230
 0.1
chr11_16889902_16890060 0.12 Egfr
 epidermal growth factor receptor
 11831
 0.19
chr17_64609780_64609995 0.12 Man2a1
 mannosidase 2, alpha 1
 9151
 0.26
chr16_25011043_25011318 0.12 A230028O05Rik
 RIKEN cDNA A230028O05 gene
 48459
 0.18
chr3_141502934_141503090 0.12 Unc5c
 unc-5 netrin receptor C
 37341
 0.18
chr14_11801019_11801346 0.12 Gm48602
 predicted gene, 48602
 33239
 0.19
chr5_125325436_125325605 0.12 Scarb1
 scavenger receptor class B, member 1
 747
 0.57
chrY_90794490_90794856 0.12 Gm47283
 predicted gene, 47283
 4222
 0.21
chr13_101895557_101895722 0.12 Gm17832
 predicted gene, 17832
 24781
 0.19
chr1_193926856_193927030 0.12 Gm21362
 predicted gene, 21362
 59934
 0.16
chr10_4599676_4599928 0.12 Esr1
 estrogen receptor 1 (alpha)
 11791
 0.21
chr3_52618299_52618553 0.12 Gm10293
 predicted pseudogene 10293
 5591
 0.27
chr6_43851681_43851832 0.12 Gm7783
 predicted gene 7783
 5148
 0.27
chr19_44398583_44398737 0.12 Scd1
 stearoyl-Coenzyme A desaturase 1
 8030
 0.15
chr5_100371529_100371680 0.12 Sec31a
 Sec31 homolog A (S. cerevisiae)
 1880
 0.3
chr5_135713964_135714115 0.12 Por
 P450 (cytochrome) oxidoreductase
 1966
 0.2
chr18_43980831_43980982 0.12 Spink5
 serine peptidase inhibitor, Kazal type 5
 17671
 0.17
chr13_46023839_46023999 0.12 Gm45949
 predicted gene, 45949
 36678
 0.16
chr8_3493535_3493936 0.12 Zfp358
 zinc finger protein 358
 565
 0.6
chr8_23189899_23190050 0.12 Gpat4
 glycerol-3-phosphate acyltransferase 4
 964
 0.41
chr11_29526849_29527005 0.12 Mtif2
 mitochondrial translational initiation factor 2
 470
 0.69
chr10_68093593_68093917 0.12 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 42871
 0.14
chr4_99028977_99029128 0.12 Angptl3
 angiopoietin-like 3
 1902
 0.32
chr16_22511358_22511522 0.12 9230117E06Rik
 RIKEN cDNA 9230117E06 gene
 40
 0.96
chr2_38585174_38585360 0.12 Gm44183
 predicted gene, 44183
 18913
 0.12
chr19_46603380_46603531 0.12 Wbp1l
 WW domain binding protein 1 like
 4331
 0.16
chr5_87499011_87499178 0.12 Ugt2a1
 UDP glucuronosyltransferase 2 family, polypeptide A1
 8223
 0.12
chr6_31110022_31110173 0.12 5330406M23Rik
 RIKEN cDNA 5330406M23 gene
 823
 0.49
chr11_16883025_16883203 0.12 Egfr
 epidermal growth factor receptor
 4964
 0.23
chr3_107315148_107315299 0.12 Rbm15
 RNA binding motif protein 15
 17878
 0.13
chr13_63231532_63231825 0.12 Aopep
 aminopeptidase O
 8351
 0.11
chr4_45514779_45514987 0.12 Gm22518
 predicted gene, 22518
 14331
 0.14
chr15_97047820_97047997 0.12 Slc38a4
 solute carrier family 38, member 4
 2179
 0.42
chr10_10925217_10925440 0.12 Gm48406
 predicted gene, 48406
 110588
 0.06
chr2_59979903_59980091 0.12 Gm13574
 predicted gene 13574
 12347
 0.19
chr8_40875940_40876218 0.12 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 1131
 0.44
chr17_27621069_27621255 0.12 Nudt3
 nudix (nucleotide diphosphate linked moiety X)-type motif 3
 1231
 0.25
chr2_32680438_32680786 0.11 Fpgs
 folylpolyglutamyl synthetase
 4392
 0.08
chr5_20881136_20881540 0.11 Phtf2
 putative homeodomain transcription factor 2
 707
 0.46
chr8_40882534_40882732 0.11 Slc7a2
 solute carrier family 7 (cationic amino acid transporter, y+ system), member 2
 7685
 0.16
chr19_10052563_10053085 0.11 Fads3
 fatty acid desaturase 3
 127
 0.94
chr10_52234541_52234692 0.11 Dcbld1
 discoidin, CUB and LCCL domain containing 1
 979
 0.54
chr2_115537784_115537935 0.11 3110099E03Rik
 RIKEN cDNA 3110099E03 gene
 10115
 0.22
chr19_58370035_58370186 0.11 Gfra1
 glial cell line derived neurotrophic factor family receptor alpha 1
 84356
 0.09
chr1_184276149_184276321 0.11 Gm37223
 predicted gene, 37223
 82094
 0.09
chr1_89710237_89710633 0.11 4933400F21Rik
 RIKEN cDNA 4933400F21 gene
 26527
 0.21
chr3_116302483_116302634 0.11 Gm29151
 predicted gene 29151
 47545
 0.11
chr13_114469994_114470145 0.11 Fst
 follistatin
 11118
 0.15
chr12_103768009_103768212 0.11 Serpina1d
 serine (or cysteine) peptidase inhibitor, clade A, member 1D
 5482
 0.12
chr10_19457260_19457442 0.11 Gm33104
 predicted gene, 33104
 29364
 0.18
chr10_4531024_4531190 0.11 Ccdc170
 coiled-coil domain containing 170
 1888
 0.34
chr11_99081665_99081816 0.11 Tns4
 tensin 4
 6399
 0.15
chr1_58190709_58190860 0.11 Aox4
 aldehyde oxidase 4
 19613
 0.16
chr8_54468376_54468527 0.11 Gm45553
 predicted gene 45553
 45699
 0.14
chr18_75499322_75499625 0.11 Gm10532
 predicted gene 10532
 15172
 0.25
chr13_51089168_51089510 0.11 Spin1
 spindlin 1
 11541
 0.24
chr1_136893539_136893740 0.11 Nr5a2
 nuclear receptor subfamily 5, group A, member 2
 46944
 0.13
chr17_80090476_80090673 0.11 Gm23125
 predicted gene, 23125
 14363
 0.14
chr16_36770901_36771058 0.11 Slc15a2
 solute carrier family 15 (H+/peptide transporter), member 2
 2299
 0.18
chr5_20858729_20858886 0.11 Phtf2
 putative homeodomain transcription factor 2
 3616
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.6 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.2 GO:1903352 ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.1 GO:0097460 ferrous iron import into cell(GO:0097460)
0.0 0.1 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0006559 L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.1 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:0019627 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.1 GO:2000437 monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:2000359 regulation of binding of sperm to zona pellucida(GO:2000359)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.0 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 0.1 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0010835 regulation of protein ADP-ribosylation(GO:0010835)
0.0 0.1 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0032754 positive regulation of interleukin-5 production(GO:0032754)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0010986 positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.2 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.0 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.1 GO:0070857 regulation of bile acid biosynthetic process(GO:0070857)
0.0 0.1 GO:1905065 positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.1 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.1 GO:0060687 regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.1 GO:0055091 phospholipid homeostasis(GO:0055091)
0.0 0.1 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0 0.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0033129 positive regulation of histone phosphorylation(GO:0033129)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.0 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.0 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.0 GO:0034287 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.0 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.0 GO:0000430 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.0 0.0 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909)
0.0 0.1 GO:1903818 positive regulation of delayed rectifier potassium channel activity(GO:1902261) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.0 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.0 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.0 GO:0048769 sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0015074 DNA integration(GO:0015074)
0.0 0.0 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.1 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.0 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.0 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:1901409 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.0 GO:0097475 motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0043102 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.0 GO:0071503 response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0 0.0 GO:0019042 viral latency(GO:0019042)
0.0 0.0 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.0 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0070295 renal water absorption(GO:0070295)
0.0 0.0 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.0 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0060926 cardiac pacemaker cell development(GO:0060926)
0.0 0.0 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.1 GO:0042436 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.0 GO:0032349 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.0 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.0 0.0 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.1 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.3 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0031933 telomeric heterochromatin(GO:0031933)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0097209 epidermal lamellar body(GO:0097209)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.0 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.0 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.0 GO:0070552 BRISC complex(GO:0070552)
0.0 0.0 GO:0048179 activin receptor complex(GO:0048179)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.0 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.0 GO:0000306 extrinsic component of vacuolar membrane(GO:0000306)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.4 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.2 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.4 GO:0016215 acyl-CoA desaturase activity(GO:0016215)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.1 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.1 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.0 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.1 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.0 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.0 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.0 GO:0000403 Y-form DNA binding(GO:0000403)
0.0 0.0 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.2 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.0 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 0.1 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.1 GO:0002094 polyprenyltransferase activity(GO:0002094)
0.0 0.2 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.1 GO:0031994 insulin-like growth factor I binding(GO:0031994)
0.0 0.0 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.2 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.0 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.4 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.0 SA PTEN PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.1 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.0 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.3 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane