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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Sox30

Z-value: 1.21

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Transcription factors associated with Sox30

Gene Symbol	Gene ID	Gene Info
Sox30 Ensembl NCBI MGI UniProt	ENSMUSG00000040489.5	SRY (sex determining region Y)-box 30

Activity of the Sox30 motif across conditions

Conditions sorted by the z-value of the Sox30 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_104346326_104346873	2.42	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	8113	0.12
chr14_116442003_116442157	2.22	Gm38045	predicted gene, 38045	308135	0.01
chr10_87920604_87920755	1.28	Tyms-ps	thymidylate synthase, pseudogene	46168	0.12
chr12_40574426_40574700	1.11	Dock4	dedicator of cytokinesis 4	128227	0.05
chr19_32992433_32992599	1.04	Gm36860	predicted gene, 36860	12453	0.25
chr12_80010993_80011167	1.03	Gm8275	predicted gene 8275	31229	0.14
chr13_24359929_24360183	0.99	Gm11342	predicted gene 11342	15894	0.12
chr5_151018980_151019139	0.99	Gm8675	predicted gene 8675	9758	0.23
chr2_72206740_72207276	0.95	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	8209	0.18
chr4_65080374_65080537	0.92	Pappa	pregnancy-associated plasma protein A	43719	0.19
chr5_125522928_125523080	0.90	Aacs	acetoacetyl-CoA synthetase	7761	0.16
chr16_81366011_81366177	0.88	Gm49555	predicted gene, 49555	75932	0.11
chr3_99188109_99188313	0.87	Gm18982	predicted gene, 18982	6930	0.13
chr1_76641343_76641507	0.86	Mir6343	microRNA 6343	131865	0.05
chr5_38117047_38117323	0.85	Stx18	syntaxin 18	3724	0.2
chr11_16839622_16839885	0.85	Egfros	epidermal growth factor receptor, opposite strand	9051	0.21
chr5_87349083_87349430	0.82	Gm42796	predicted gene 42796	6579	0.11
chr1_41559831_41559986	0.82	Gm28634	predicted gene 28634	30365	0.26
chr4_49550356_49550507	0.80	Aldob	aldolase B, fructose-bisphosphate	885	0.51
chr18_56396921_56397088	0.79	Gramd3	GRAM domain containing 3	3333	0.25
chr9_122865001_122865302	0.77	Zfp445	zinc finger protein 445	783	0.46
chr19_33489637_33489788	0.76	Lipo5	lipase, member O5	16521	0.14
chr17_63010676_63010827	0.75	Gm25348	predicted gene, 25348	86249	0.1
chr2_58784544_58784695	0.75	Upp2	uridine phosphorylase 2	19294	0.19
chr19_33480626_33480777	0.73	Lipo5	lipase, member O5	7510	0.16
chr3_24378479_24378630	0.72	Gm7536	predicted gene 7536	45486	0.21
chr1_71807937_71808302	0.68	Gm37217	predicted gene, 37217	38491	0.15
chr1_67138759_67139000	0.68	Cps1	carbamoyl-phosphate synthetase 1	15853	0.23
chr3_18137155_18137306	0.65	Gm23686	predicted gene, 23686	40395	0.15
chr8_82402195_82403147	0.59	Il15	interleukin 15	101	0.98
chr7_126673507_126673658	0.58	Sgf29	SAGA complex associated factor 29	1551	0.16
chr11_16761103_16761540	0.58	Egfr	epidermal growth factor receptor	9091	0.2
chr6_149225033_149225369	0.58	1700003I16Rik	RIKEN cDNA 1700003I16 gene	10016	0.16
chr9_74872523_74872674	0.56	Onecut1	one cut domain, family member 1	6114	0.16
chr3_148786931_148787086	0.56	Adgrl2	adhesion G protein-coupled receptor L2	35971	0.22
chr2_126934794_126934945	0.54	Sppl2a	signal peptide peptidase like 2A	1634	0.35
chr2_148017296_148017455	0.54	9030622O22Rik	RIKEN cDNA 9030622O22 gene	20895	0.16
chr17_89449780_89449962	0.54	Gm4719	predicted gene 4719	70630	0.13
chr6_28491147_28491308	0.53	Snd1	staphylococcal nuclease and tudor domain containing 1	10798	0.14
chr10_95254224_95254433	0.53	Gm48880	predicted gene, 48880	60525	0.08
chr12_104083020_104083260	0.52	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	2491	0.16
chr7_140719940_140720091	0.52	Olfr542-ps1	olfactory receptor 542, pseudogene 1	1267	0.28
chr6_52606460_52606970	0.52	Gm44434	predicted gene, 44434	3470	0.19
chr6_37748273_37748424	0.51	Atp6v0c-ps2	ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2	57738	0.12
chr2_73491256_73491419	0.50	Wipf1	WAS/WASL interacting protein family, member 1	4868	0.19
chr5_147312834_147312985	0.50	Cdx2	caudal type homeobox 2	5639	0.11
chr19_40156899_40157166	0.49	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	30254	0.13
chr2_73628966_73629117	0.49	Chn1	chimerin 1	3301	0.21
chr3_116915063_116915225	0.47	Frrs1	ferric-chelate reductase 1	18434	0.13
chr4_62016868_62017437	0.46	Mup-ps20	major urinary protein, pseudogene 20	2295	0.23
chr5_148633016_148633167	0.45	Gm29815	predicted gene, 29815	19447	0.18
chr5_125506718_125506869	0.45	Aacs	acetoacetyl-CoA synthetase	644	0.65
chr1_107942218_107942404	0.45	D830032E09Rik	RIKEN cDNA D830032E09 gene	5602	0.2
chr10_121457902_121458053	0.45	Rassf3	Ras association (RalGDS/AF-6) domain family member 3	4236	0.14
chr3_116520495_116520697	0.44	Dbt	dihydrolipoamide branched chain transacylase E2	268	0.83
chr5_8667945_8668138	0.43	Gm42684	predicted gene 42684	1479	0.38
chr7_120187015_120187182	0.43	Anks4b	ankyrin repeat and sterile alpha motif domain containing 4B	13240	0.13
chr3_152247820_152247987	0.42	Nexn	nexilin	361	0.8
chr4_53222171_53222454	0.42	4930412L05Rik	RIKEN cDNA 4930412L05 gene	4455	0.21
chr8_64837268_64837552	0.41	Gm45345	predicted gene 45345	824	0.55
chr8_93190868_93191185	0.41	Gm45909	predicted gene 45909	332	0.84
chr5_87562697_87562848	0.40	Sult1d1	sulfotransferase family 1D, member 1	2581	0.17
chr19_12654451_12654602	0.40	Gm24521	predicted gene, 24521	10729	0.09
chr6_24049175_24049330	0.40	Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	59319	0.12
chr18_76968080_76968231	0.40	Hdhd2	haloacid dehalogenase-like hydrolase domain containing 2	23718	0.15
chr17_15077386_15077778	0.39	Ermard	ER membrane associated RNA degradation	11967	0.15
chr19_40141682_40141833	0.39	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	45529	0.11
chr6_121171179_121171645	0.39	Pex26	peroxisomal biogenesis factor 26	12255	0.13
chr2_122149958_122150187	0.39	B2m	beta-2 microglobulin	2386	0.19
chr8_61543473_61543757	0.39	Palld	palladin, cytoskeletal associated protein	9774	0.25
chr9_122847374_122847863	0.38	Gm47140	predicted gene, 47140	800	0.46
chr15_67149186_67149444	0.38	St3gal1	ST3 beta-galactoside alpha-2,3-sialyltransferase 1	20292	0.24
chr6_94083257_94083610	0.38	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	169743	0.03
chr7_134753489_134753670	0.38	Dock1	dedicator of cytokinesis 1	23876	0.24
chr5_130007895_130008067	0.37	Gusb	glucuronidase, beta	4932	0.13
chr6_149134216_149134396	0.37	Gm10203	predicted gene 10203	4136	0.14
chr17_32944138_32944328	0.37	Cyp4f13	cytochrome P450, family 4, subfamily f, polypeptide 13	3102	0.14
chr15_10192008_10192172	0.37	Prlr	prolactin receptor	14309	0.28
chr2_180678351_180678502	0.37	Dido1	death inducer-obliterator 1	2471	0.19
chr11_16821774_16821942	0.36	Egfros	epidermal growth factor receptor, opposite strand	8844	0.22
chr2_180695831_180695982	0.36	Gm22502	predicted gene, 22502	2157	0.2
chr11_17651863_17652036	0.35	Gm12016	predicted gene 12016	12766	0.3
chr6_149150480_149150842	0.35	Etfbkmt	electron transfer flavoprotein beta subunit lysine methyltransferase	9015	0.13
chr5_86920931_86921145	0.35	Gm25211	predicted gene, 25211	4716	0.11
chr14_88428338_88428489	0.35	Gm48930	predicted gene, 48930	12388	0.18
chr8_26351792_26351988	0.34	Gm31784	predicted gene, 31784	39556	0.12
chr5_151394352_151394569	0.34	1700028E10Rik	RIKEN cDNA 1700028E10 gene	5684	0.19
chr1_85325110_85325261	0.34	Gm16025	predicted gene 16025	1544	0.27
chr10_68113055_68113212	0.34	Arid5b	AT rich interactive domain 5B (MRF1-like)	23493	0.21
chr7_90142238_90142404	0.34	Gm45222	predicted gene 45222	3627	0.14
chr9_74894770_74895613	0.34	Onecut1	one cut domain, family member 1	28707	0.13
chr19_10099300_10099508	0.34	Fads2	fatty acid desaturase 2	2342	0.23
chr11_16798476_16798627	0.34	Egfros	epidermal growth factor receptor, opposite strand	32151	0.16
chr11_99056309_99056460	0.33	Igfbp4	insulin-like growth factor binding protein 4	9073	0.12
chr10_87545070_87545221	0.33	Pah	phenylalanine hydroxylase	1528	0.44
chr12_57538162_57538324	0.33	Foxa1	forkhead box A1	7878	0.15
chr9_122848440_122848788	0.33	Gm47140	predicted gene, 47140	196	0.89
chr16_93346268_93346483	0.33	1810053B23Rik	RIKEN cDNA 1810053B23 gene	6814	0.19
chr5_62748532_62748735	0.33	Arap2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2	17487	0.24
chr2_147998244_147998434	0.33	9030622O22Rik	RIKEN cDNA 9030622O22 gene	22154	0.18
chr1_162963349_162963500	0.33	Gm37273	predicted gene, 37273	19590	0.14
chr16_23326741_23326947	0.33	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	36374	0.13
chr13_49644072_49644240	0.33	Cenpp	centromere protein P	8611	0.12
chr3_57421025_57421339	0.32	Tm4sf4	transmembrane 4 superfamily member 4	4132	0.26
chr10_95424636_95424797	0.32	5730420D15Rik	RIKEN cDNA 5730420D15 gene	7341	0.13
chr10_68121308_68121503	0.32	Arid5b	AT rich interactive domain 5B (MRF1-like)	15221	0.24
chr11_16829553_16829792	0.32	Egfros	epidermal growth factor receptor, opposite strand	1030	0.59
chr11_72631760_72631911	0.32	Gm24143	predicted gene, 24143	15685	0.13
chr5_90457553_90457769	0.32	Alb	albumin	3236	0.21
chr10_87923338_87923500	0.32	Tyms-ps	thymidylate synthase, pseudogene	43428	0.12
chr14_34328663_34328894	0.32	Glud1	glutamate dehydrogenase 1	116	0.93
chr2_73939236_73939432	0.31	Gm13668	predicted gene 13668	21335	0.17
chr18_9487035_9487277	0.31	Gm7527	predicted gene 7527	8465	0.16
chr1_24116155_24116306	0.31	Gm26607	predicted gene, 26607	9045	0.17
chr18_33352007_33352191	0.31	Gm5503	predicted gene 5503	32856	0.21
chr7_63899068_63899509	0.31	Gm27252	predicted gene 27252	1314	0.37
chr17_28428613_28428954	0.31	Fkbp5	FK506 binding protein 5	154	0.91
chr17_64720655_64720806	0.30	Man2a1	mannosidase 2, alpha 1	7111	0.22
chr17_46053621_46054045	0.30	Vegfa	vascular endothelial growth factor A	21464	0.12
chr2_121439848_121440228	0.30	Ell3	elongation factor RNA polymerase II-like 3	1113	0.25
chr1_127898839_127898990	0.30	Rab3gap1	RAB3 GTPase activating protein subunit 1	1999	0.31
chr5_36621044_36621360	0.30	D5Ertd579e	DNA segment, Chr 5, ERATO Doi 579, expressed	53	0.96
chrX_139665962_139666117	0.30	Gm6322	predicted gene 6322	11450	0.17
chr1_126431765_126431942	0.30	Nckap5	NCK-associated protein 5	16603	0.29
chr14_35502504_35502655	0.30	Gm19016	predicted gene, 19016	46547	0.17
chr7_72323573_72323742	0.30	Mctp2	multiple C2 domains, transmembrane 2	17049	0.28
chr16_86389664_86389844	0.30	Gm32357	predicted gene, 32357	153583	0.04
chr4_57122143_57122466	0.30	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	2244	0.35
chr15_4678897_4679270	0.30	C6	complement component 6	48092	0.17
chr9_111128128_111128279	0.29	Lrrfip2	leucine rich repeat (in FLII) interacting protein 2	8528	0.16
chr14_122876950_122877397	0.29	Pcca	propionyl-Coenzyme A carboxylase, alpha polypeptide	1238	0.47
chr2_109688795_109688948	0.29	Bdnf	brain derived neurotrophic factor	3565	0.23
chr13_85208789_85208956	0.29	Ccnh	cyclin H	2450	0.3
chr5_125528759_125528910	0.29	Tmem132b	transmembrane protein 132B	2940	0.22
chr11_104387417_104387568	0.29	Gm47315	predicted gene, 47315	37808	0.13
chr8_105009723_105009901	0.29	Ces2h	carboxylesterase 2H	8959	0.1
chr8_90871765_90872190	0.29	Gm45640	predicted gene 45640	4604	0.15
chr9_35123533_35123708	0.29	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	4352	0.15
chr14_13625050_13625231	0.29	Sntn	sentan, cilia apical structure protein	45736	0.17
chr3_79555181_79555357	0.29	Gm3513	predicted gene 3513	3076	0.17
chr6_149359539_149359690	0.29	Gm15784	predicted gene 15784	2072	0.23
chr11_29526849_29527005	0.29	Mtif2	mitochondrial translational initiation factor 2	470	0.69
chr11_7815566_7815774	0.29	Gm27393	predicted gene, 27393	70835	0.13
chr18_64079171_64079335	0.29	Gm6974	predicted gene 6974	2167	0.36
chr2_42039001_42039161	0.28	Gm13461	predicted gene 13461	50252	0.18
chr5_67300787_67300957	0.28	Slc30a9	solute carrier family 30 (zinc transporter), member 9	6083	0.19
chr6_108466356_108466533	0.28	Gm44101	predicted gene, 44101	6131	0.18
chr17_32935826_32936018	0.28	Cyp4f13	cytochrome P450, family 4, subfamily f, polypeptide 13	4914	0.11
chr12_70196878_70197068	0.28	Pygl	liver glycogen phosphorylase	868	0.54
chr11_60201956_60202762	0.28	Mir6922	microRNA 6922	32	0.63
chr18_12663657_12663965	0.28	Gm41668	predicted gene, 41668	15392	0.14
chr15_3476580_3476767	0.28	Ghr	growth hormone receptor	5029	0.32
chr7_44815923_44816372	0.28	Nup62	nucleoporin 62	59	0.66
chr13_23804366_23804536	0.28	Gm11337	predicted gene 11337	148	0.87
chr2_32095451_32095626	0.27	Plpp7	phospholipid phosphatase 7 (inactive)	10	0.96
chr6_14778417_14778568	0.27	Ppp1r3a	protein phosphatase 1, regulatory subunit 3A	23218	0.27
chr8_82524759_82525044	0.27	Gm8167	predicted gene 8167	52866	0.15
chr4_8688195_8688404	0.27	Chd7	chromodomain helicase DNA binding protein 7	2107	0.38
chr1_23279889_23280199	0.27	Mir30a	microRNA 30a	7775	0.12
chr11_16807603_16807776	0.27	Egfros	epidermal growth factor receptor, opposite strand	23013	0.19
chr1_44575664_44575838	0.27	Gm37626	predicted gene, 37626	14866	0.19
chr3_14685860_14686011	0.27	Gm5843	predicted gene 5843	36481	0.12
chr10_123842451_123842602	0.27	Gm18510	predicted gene, 18510	49372	0.19
chr3_28591458_28591833	0.27	Tnik	TRAF2 and NCK interacting kinase	38227	0.18
chr1_107716693_107716857	0.27	Gm15389	predicted gene 15389	29767	0.18
chr2_4998266_4998605	0.27	Mcm10	minichromosome maintenance 10 replication initiation factor	2541	0.2
chr1_33939932_33940113	0.27	Gm37354	predicted gene, 37354	17567	0.12
chr11_71013317_71013604	0.27	Derl2	Der1-like domain family, member 2	5752	0.1
chr1_170137562_170137720	0.26	Uap1	UDP-N-acetylglucosamine pyrophosphorylase 1	6072	0.16
chr1_92944221_92944381	0.26	Capn10	calpain 10	1597	0.22
chr4_99037726_99038187	0.26	Angptl3	angiopoietin-like 3	4753	0.21
chr15_75205125_75205276	0.26	Gm28117	predicted gene 28117	7533	0.12
chr13_24144521_24144672	0.26	Carmil1	capping protein regulator and myosin 1 linker 1	10613	0.19
chr11_11845100_11845416	0.26	Ddc	dopa decarboxylase	8978	0.18
chr6_28734300_28734519	0.26	Snd1	staphylococcal nuclease and tudor domain containing 1	28689	0.19
chr15_58971828_58971979	0.26	Mtss1	MTSS I-BAR domain containing 1	636	0.67
chr8_93173439_93173590	0.26	Ces1d	carboxylesterase 1D	1775	0.27
chr5_130020282_130020619	0.26	Asl	argininosuccinate lyase	3850	0.14
chr2_170269712_170270084	0.26	Gm14270	predicted gene 14270	15137	0.23
chr4_76360115_76360401	0.26	Ptprd	protein tyrosine phosphatase, receptor type, D	16015	0.23
chr19_36323375_36323536	0.25	Gm47735	predicted gene, 47735	24843	0.13
chr11_78846353_78846604	0.25	Lyrm9	LYR motif containing 9	19849	0.15
chr5_147224671_147224829	0.25	Gm24556	predicted gene, 24556	24497	0.11
chr4_150709744_150709942	0.25	Gm16079	predicted gene 16079	31051	0.16
chr17_14962228_14962437	0.25	Phf10	PHD finger protein 10	1059	0.36
chr7_73557395_73557719	0.25	1810026B05Rik	RIKEN cDNA 1810026B05 gene	416	0.74
chr2_60288667_60288955	0.25	Cd302	CD302 antigen	4323	0.19
chr11_111297916_111298094	0.25	Gm11675	predicted gene 11675	21905	0.28
chr4_19491208_19491365	0.25	Cpne3	copine III	52392	0.15
chr1_136140658_136140838	0.25	Kif21b	kinesin family member 21B	9294	0.11
chr3_18877514_18877665	0.25	Gm30341	predicted gene, 30341	124512	0.06
chr6_83922439_83922590	0.25	Zfp638	zinc finger protein 638	6341	0.13
chr8_9027774_9027937	0.25	Gm44515	predicted gene 44515	95156	0.06
chr4_44784029_44784206	0.25	Zcchc7	zinc finger, CCHC domain containing 7	23673	0.15
chr6_71423223_71423388	0.24	Gm44130	predicted gene, 44130	11802	0.1
chr2_134500653_134500804	0.24	Hao1	hydroxyacid oxidase 1, liver	53579	0.17
chr11_82032806_82032957	0.24	Ccl2	chemokine (C-C motif) ligand 2	2690	0.17
chr1_159231811_159232536	0.24	Cop1	COP1, E3 ubiquitin ligase	147	0.95
chr6_89381990_89382152	0.24	Plxna1	plexin A1	19451	0.17
chr14_58710319_58710470	0.24	Gm25614	predicted gene, 25614	59994	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox30

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.2	0.5	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.6	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.1	0.3	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.5	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.3	GO:0006538	glutamate catabolic process(GO:0006538)
0.1	0.3	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.2	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.2	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.1	0.2	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.1	0.2	GO:0003221	right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0	0.1	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.3	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.3	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:0032377	regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0	0.4	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.3	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.2	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.1	GO:1901656	glycoside transport(GO:1901656)
0.0	0.1	GO:0097460	ferrous iron import into cell(GO:0097460)
0.0	0.1	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.3	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.1	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0089700	protein kinase D signaling(GO:0089700)
0.0	0.1	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.0	0.1	GO:0048369	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.0	GO:0052695	cellular glucuronidation(GO:0052695)
0.0	0.2	GO:0071318	cellular response to ATP(GO:0071318)
0.0	0.1	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.1	GO:0050859	negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0	0.2	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.1	GO:0042414	epinephrine metabolic process(GO:0042414)
0.0	0.1	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.0	GO:0070346	positive regulation of fat cell proliferation(GO:0070346)
0.0	0.1	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.2	GO:1901409	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.3	GO:0010832	negative regulation of myotube differentiation(GO:0010832)
0.0	0.6	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0060399	positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0	0.1	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.0	GO:2000809	positive regulation of synaptic vesicle clustering(GO:2000809)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.0	0.2	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0045200	establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:0030388	fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.4	GO:0052696	flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:0045963	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.1	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.1	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.1	GO:0030638	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.6	GO:0070542	response to fatty acid(GO:0070542)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.1	GO:0070649	formin-nucleated actin cable assembly(GO:0070649)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.0	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.0	GO:0051891	positive regulation of cardioblast differentiation(GO:0051891)
0.0	0.0	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.0	GO:0055064	chloride ion homeostasis(GO:0055064)
0.0	0.0	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0042421	norepinephrine biosynthetic process(GO:0042421)
0.0	0.1	GO:0046668	regulation of retinal cell programmed cell death(GO:0046668)
0.0	0.0	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.2	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.0	GO:0070508	sterol import(GO:0035376) cholesterol import(GO:0070508)
0.0	0.0	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.0	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.0	0.0	GO:0097503	sialylation(GO:0097503)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0003419	growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0	0.0	GO:0009812	flavonoid metabolic process(GO:0009812)
0.0	0.0	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.1	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.1	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.1	GO:0046643	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.2	GO:0042059	negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0	0.0	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.0	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.0	GO:0060900	embryonic camera-type eye formation(GO:0060900)
0.0	0.0	GO:0018406	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.1	GO:0051123	RNA polymerase II transcriptional preinitiation complex assembly(GO:0051123)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:1904684	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:0072393	microtubule anchoring at microtubule organizing center(GO:0072393)
0.0	0.1	GO:0009642	response to light intensity(GO:0009642)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0018002	N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.0	0.0	GO:0072566	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.0	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.0	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.2	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0003383	apical constriction(GO:0003383)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.5	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.3	GO:0097433	dense body(GO:0097433)
0.1	0.3	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.0	0.2	GO:0071556	integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0031298	replication fork protection complex(GO:0031298)
0.0	0.0	GO:0044299	C-fiber(GO:0044299)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0005587	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.2	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.2	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.6	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.1	0.4	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.5	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.3	GO:0070728	leucine binding(GO:0070728)
0.1	0.2	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.1	0.2	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.1	0.2	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0051425	PTB domain binding(GO:0051425)
0.0	0.2	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.2	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.3	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.2	GO:0046790	virion binding(GO:0046790)
0.0	0.1	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.3	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.2	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.1	GO:0038181	bile acid receptor activity(GO:0038181)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.0	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.3	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.1	GO:0001075	transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0	0.1	GO:0001025	RNA polymerase III transcription factor binding(GO:0001025)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0004802	transketolase activity(GO:0004802)
0.0	0.2	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.2	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.2	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.0	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0015181	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.1	GO:0043426	MRF binding(GO:0043426)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0035174	histone serine kinase activity(GO:0035174)
0.0	0.2	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0070180	large ribosomal subunit rRNA binding(GO:0070180)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.3	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.1	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.5	GO:0008391	arachidonic acid monooxygenase activity(GO:0008391)
0.0	0.1	GO:0042809	vitamin D receptor binding(GO:0042809)
0.0	0.4	GO:0018734	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.0	GO:0038100	nodal binding(GO:0038100)
0.0	0.2	GO:0016805	dipeptidase activity(GO:0016805)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.0	GO:1990190	peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0034834	2,3-dihydroxy DDT 1,2-dioxygenase activity(GO:0018542) phenanthrene dioxygenase activity(GO:0018555) 2,2',3-trihydroxybiphenyl dioxygenase activity(GO:0018556) 1,2-dihydroxyfluorene 1,1-alpha-dioxygenase activity(GO:0018557) 5,6-dihydroxy-3-methyl-2-oxo-1,2-dihydroquinoline dioxygenase activity(GO:0018558) 1,1-dichloro-2-(dihydroxy-4-chlorophenyl)-(4-chlorophenyl)ethene 1,2-dioxygenase activity(GO:0018559) protocatechuate 3,4-dioxygenase type II activity(GO:0018560) 2'-aminobiphenyl-2,3-diol 1,2-dioxygenase activity(GO:0018561) 3,4-dihydroxyfluorene 4,4-alpha-dioxygenase activity(GO:0018562) 2,3-dihydroxy-ethylbenzene 1,2-dioxygenase activity(GO:0018563) carbazole 1,9a-dioxygenase activity(GO:0018564) dihydroxydibenzothiophene dioxygenase activity(GO:0018565) 1,2-dihydroxynaphthalene-6-sulfonate 1,8a-dioxygenase activity(GO:0018566) styrene dioxygenase activity(GO:0018567) 3,4-dihydroxyphenanthrene dioxygenase activity(GO:0018568) hydroquinone 1,2-dioxygenase activity(GO:0018569) p-cumate 2,3-dioxygenase activity(GO:0018570) 2,3-dihydroxy-p-cumate dioxygenase activity(GO:0018571) 3,5-dichlorocatechol 1,2-dioxygenase activity(GO:0018572) 2-aminophenol 1,6-dioxygenase activity(GO:0018573) 2,6-dichloro-p-hydroquinone 1,2-dioxygenase activity(GO:0018574) chlorocatechol 1,2-dioxygenase activity(GO:0018575) catechol dioxygenase activity(GO:0019114) dihydroxyfluorene dioxygenase activity(GO:0019117) 5-aminosalicylate dioxygenase activity(GO:0034543) 3-hydroxy-2-naphthoate 2,3-dioxygenase activity(GO:0034803) benzo(a)pyrene 11,12-dioxygenase activity(GO:0034806) benzo(a)pyrene 4,5-dioxygenase activity(GO:0034808) 4,5-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034810) benzo(a)pyrene 9,10-dioxygenase activity(GO:0034811) 9,10-dihydroxybenzo(a)pyrene dioxygenase activity(GO:0034812) benzo(a)pyrene 7,8-dioxygenase activity(GO:0034813) 7,8-dihydroxy benzo(a)pyrene dioxygenase activity(GO:0034814) 1,2-dihydroxy-5,6,7,8-tetrahydronaphthalene extradiol dioxygenase activity(GO:0034827) 2-mercaptobenzothiazole dioxygenase activity(GO:0034834) pyridine-3,4-diol dioxygenase activity(GO:0034895) pyrene dioxygenase activity(GO:0034920) 4,5-dihydroxypyrene dioxygenase activity(GO:0034922) phenanthrene-4-carboxylate dioxygenase activity(GO:0034934) tetrachlorobenzene dioxygenase activity(GO:0034935) 4,6-dichloro-3-methylcatechol 1,2-dioxygenase activity(GO:0034936) 2,3-dihydroxydiphenyl ether dioxygenase activity(GO:0034955) diphenyl ether 1,2-dioxygenase activity(GO:0034956) arachidonate 8(S)-lipoxygenase activity(GO:0036403) 4-hydroxycatechol 1,2-dioxygenase activity(GO:0047074)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.0	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.4	GO:0017046	peptide hormone binding(GO:0017046)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
1.0	PID HNF3B PATHWAY	FOXA2 and FOXA3 transcription factor networks
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.2	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.3	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.6	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.2	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.2	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.6	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.3	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.2	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.2	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.1	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism

Results for Sox30

Z-value: 1.21

Motif logo

Transcription factors associated with Sox30

Activity of the Sox30 motif across conditions

Conditions sorted by the z-value of the Sox30 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox30

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: