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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Sox5_Sry

Z-value: 0.46

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Transcription factors associated with Sox5_Sry

Gene Symbol	Gene ID	Gene Info
Sox5 Ensembl NCBI MGI UniProt	ENSMUSG00000041540.10	SRY (sex determining region Y)-box 5
Sry Ensembl NCBI MGI UniProt	ENSMUSG00000069036.3	sex determining region of Chr Y

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr6_144155774_144155925	Sox5	48208	0.183274	-0.91	1.2e-02	Click!
chr6_144204039_144204246	Sox5	85	0.985389	-0.81	5.1e-02	Click!
chr6_144753669_144753921	Sox5	28124	0.135933	-0.80	5.6e-02	Click!
chr6_144210184_144210365	Sox5	706	0.810293	-0.80	5.7e-02	Click!
chr6_144209110_144209295	Sox5	250	0.959818	-0.78	6.5e-02	Click!

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr3_116510337_116510525	0.17	Rtca	RNA 3'-terminal phosphate cyclase	2223	0.16
chr11_16704048_16704199	0.16	Gm25698	predicted gene, 25698	28588	0.15
chr7_140772355_140773139	0.15	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	8266	0.09
chr3_69094579_69094744	0.14	Gm22009	predicted gene, 22009	9214	0.13
chr19_40156899_40157166	0.14	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	30254	0.13
chr15_59391938_59392317	0.14	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	17840	0.18
chr1_92683263_92683419	0.14	Gm29483	predicted gene 29483	33861	0.09
chr1_74807738_74808135	0.14	Wnt10a	wingless-type MMTV integration site family, member 10A	14573	0.11
chr2_147988721_147988917	0.13	9030622O22Rik	RIKEN cDNA 9030622O22 gene	12634	0.21
chr9_74872523_74872674	0.13	Onecut1	one cut domain, family member 1	6114	0.16
chr15_102116938_102117135	0.13	Tns2	tensin 2	1897	0.2
chr16_24121120_24121271	0.12	Gm31583	predicted gene, 31583	31106	0.14
chr4_114958381_114958568	0.12	Cmpk1	cytidine monophosphate (UMP-CMP) kinase 1	28598	0.11
chr12_104083020_104083260	0.12	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	2491	0.16
chr12_37050724_37050882	0.11	Gm48617	predicted gene, 48617	1586	0.37
chr7_134497342_134497526	0.11	D7Ertd443e	DNA segment, Chr 7, ERATO Doi 443, expressed	1550	0.55
chr18_16662543_16662742	0.10	Cdh2	cadherin 2	7427	0.29
chr15_26639292_26639449	0.10	9430068D22Rik	RIKEN cDNA 9430068D22 gene	5919	0.2
chr11_16821774_16821942	0.10	Egfros	epidermal growth factor receptor, opposite strand	8844	0.22
chr16_49049395_49049546	0.10	Myh15	myosin, heavy chain 15	8016	0.22
chr1_88064051_88064407	0.10	AC087801.2	UDP glucuronosyltransferase 1 family, polypeptide A9 (Ugt1a9), pseudogene	3105	0.1
chr3_80042843_80043016	0.10	A330069K06Rik	RIKEN cDNA A330069K06 gene	11963	0.22
chr2_178471902_178472068	0.10	Cdh26	cadherin-like 26	11355	0.22
chr14_66023636_66023794	0.10	Gulo	gulonolactone (L-) oxidase	14508	0.15
chr3_25017765_25017942	0.09	Gm42774	predicted gene 42774	10148	0.29
chr13_90739139_90739300	0.09	Gm44338	predicted gene, 44338	20893	0.2
chr2_149993027_149993210	0.09	Gm14140	predicted gene 14140	118458	0.05
chr11_49837892_49838056	0.09	Mapk9	mitogen-activated protein kinase 9	8777	0.16
chr10_59537699_59537863	0.09	Gm10322	predicted gene 10322	78282	0.08
chr10_20749070_20749231	0.09	Gm48651	predicted gene, 48651	6967	0.23
chr3_10136245_10136401	0.09	Gm37308	predicted gene, 37308	46368	0.08
chr2_84180208_84180377	0.09	Gm25972	predicted gene, 25972	30237	0.16
chr1_88048809_88049389	0.08	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	6289	0.08
chr13_44026422_44026628	0.08	Gm33489	predicted gene, 33489	8003	0.22
chr2_11597723_11597874	0.08	Rbm17	RNA binding motif protein 17	5464	0.14
chr1_71807937_71808302	0.08	Gm37217	predicted gene, 37217	38491	0.15
chr18_43980831_43980982	0.08	Spink5	serine peptidase inhibitor, Kazal type 5	17671	0.17
chr9_32656566_32656728	0.08	Ets1	E26 avian leukemia oncogene 1, 5' domain	20399	0.15
chr9_100488481_100488638	0.08	Il20rb	interleukin 20 receptor beta	1771	0.29
chr2_22587699_22587875	0.08	Gm13341	predicted gene 13341	175	0.91
chr14_7840036_7840206	0.08	Flnb	filamin, beta	22164	0.15
chr17_5324481_5324860	0.08	Gm29050	predicted gene 29050	64093	0.11
chr6_77098640_77098806	0.08	Ctnna2	catenin (cadherin associated protein), alpha 2	45220	0.19
chr6_101160855_101161061	0.08	Gm19726	predicted gene, 19726	14479	0.15
chr2_83740744_83740901	0.08	Dnmt3l-ps1	DNA methyltransferase 3-like, pseudogene 1	4914	0.17
chr13_110398929_110399098	0.08	Plk2	polo like kinase 2	1216	0.56
chr5_125518895_125519046	0.08	Aacs	acetoacetyl-CoA synthetase	3727	0.19
chr4_70531154_70531323	0.08	Megf9	multiple EGF-like-domains 9	3690	0.37
chr13_63298050_63298241	0.08	Aopep	aminopeptidase O	648	0.44
chr3_121982496_121982688	0.08	Arhgap29	Rho GTPase activating protein 29	1042	0.54
chr4_80003665_80003823	0.08	Gm11408	predicted gene 11408	170	0.59
chr15_6248496_6248831	0.08	Dab2	disabled 2, mitogen-responsive phosphoprotein	51125	0.13
chr4_55750022_55750212	0.08	Gm12506	predicted gene 12506	144968	0.04
chr9_53288790_53288968	0.08	Exph5	exophilin 5	12791	0.18
chr7_140767825_140767976	0.07	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	3419	0.12
chr16_91411218_91411402	0.07	Il10rb	interleukin 10 receptor, beta	4866	0.12
chrX_116629798_116629984	0.07	H2ab2	H2A.B variant histone 2	51287	0.17
chr16_23326741_23326947	0.07	St6gal1	beta galactoside alpha 2,6 sialyltransferase 1	36374	0.13
chr17_31079236_31079399	0.07	Gm25447	predicted gene, 25447	19713	0.12
chr13_80886812_80887097	0.07	Arrdc3	arrestin domain containing 3	859	0.49
chr1_74027353_74027507	0.07	Tns1	tensin 1	9703	0.23
chr2_128719461_128719612	0.07	Mertk	MER proto-oncogene tyrosine kinase	20580	0.14
chr9_85369091_85369242	0.07	Gm48832	predicted gene, 48832	21101	0.14
chr10_37711570_37711751	0.07	Gm24710	predicted gene, 24710	220020	0.02
chr2_46365879_46366164	0.07	Gm13469	predicted gene 13469	40548	0.18
chr1_172525495_172525646	0.07	Cfap45	cilia and flagella associated protein 45	479	0.67
chr1_70811018_70811204	0.07	Vwc2l	von Willebrand factor C domain-containing protein 2-like	85188	0.1
chr5_74647970_74648138	0.07	Lnx1	ligand of numb-protein X 1	24533	0.16
chr10_19904541_19904692	0.07	Pex7	peroxisomal biogenesis factor 7	3031	0.24
chr5_92858921_92859073	0.07	Shroom3	shroom family member 3	2526	0.33
chr2_163586943_163587113	0.07	Ttpal	tocopherol (alpha) transfer protein-like	15286	0.13
chr5_17836112_17836269	0.07	Cd36	CD36 molecule	473	0.89
chr4_86047006_86047165	0.07	Gm25811	predicted gene, 25811	3591	0.3
chr4_59292456_59292607	0.07	Susd1	sushi domain containing 1	23435	0.17
chr18_60748821_60749236	0.07	Ndst1	N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1	378	0.77
chr3_39220363_39220530	0.07	Gm43008	predicted gene 43008	2600	0.39
chr8_11148911_11149083	0.07	Gm44717	predicted gene 44717	249	0.91
chr10_80917355_80917522	0.07	Lmnb2	lamin B2	413	0.7
chr6_91424605_91424772	0.07	Gm4575	predicted gene 4575	4195	0.12
chr18_78260055_78260206	0.07	Slc14a2	solute carrier family 14 (urea transporter), member 2	51036	0.15
chr11_107402263_107402420	0.07	Gm11713	predicted gene 11713	8049	0.14
chr11_107276986_107277168	0.07	Gm11719	predicted gene 11719	53631	0.09
chr12_54671337_54671527	0.07	Gm24971	predicted gene, 24971	4646	0.08
chr19_27672733_27673067	0.07	Gm24782	predicted gene, 24782	31107	0.23
chr1_60716026_60716187	0.07	Cd28	CD28 antigen	694	0.59
chr13_90799244_90799545	0.07	Gm47521	predicted gene, 47521	21311	0.19
chr1_174742793_174742954	0.07	Fmn2	formin 2	28547	0.24
chr14_31101945_31102096	0.07	Pbrm1	polybromo 1	17816	0.09
chr19_12613775_12613971	0.07	Gm4952	predicted gene 4952	13857	0.09
chr6_31148380_31148897	0.07	Gm37728	predicted gene, 37728	1219	0.36
chr10_126001088_126001318	0.06	Lrig3	leucine-rich repeats and immunoglobulin-like domains 3	10428	0.26
chr17_73786615_73786813	0.06	Ehd3	EH-domain containing 3	17420	0.2
chr17_27480362_27480514	0.06	Grm4	glutamate receptor, metabotropic 4	7122	0.11
chr10_87030552_87030730	0.06	Stab2	stabilin 2	22616	0.14
chr1_134079839_134079990	0.06	Btg2	BTG anti-proliferation factor 2	794	0.53
chr1_170972984_170973148	0.06	Gm38204	predicted gene, 38204	307	0.79
chr6_141348213_141348590	0.06	Gm10400	predicted gene 10400	7848	0.26
chr13_94037879_94038063	0.06	Cycs-ps3	cytochrome c, pseudogene 3	15872	0.17
chr15_25531182_25531388	0.06	Gm36642	predicted gene, 36642	61806	0.1
chr8_109993075_109993269	0.06	Tat	tyrosine aminotransferase	2666	0.18
chr19_36803505_36803664	0.06	Gm50112	predicted gene, 50112	15064	0.19
chr6_35253418_35253775	0.06	1810058I24Rik	RIKEN cDNA 1810058I24 gene	864	0.54
chr13_107798210_107798399	0.06	Gm22118	predicted gene, 22118	30976	0.19
chr10_84581307_84581543	0.06	Tcp11l2	t-complex 11 (mouse) like 2	4528	0.15
chr9_70011238_70011422	0.06	Gtf2a2	general transcription factor II A, 2	1220	0.39
chr6_113038436_113038611	0.06	Gm23244	predicted gene, 23244	2589	0.16
chr1_60833760_60833934	0.06	Gm11581	predicted gene 11581	24731	0.11
chr1_88044946_88045337	0.06	AC087801.1	UDP glycosyltransferase 1 family (Ytg1) pseudogene	7541	0.08
chrX_20561959_20562110	0.06	Rgn	regucalcin	12247	0.13
chr1_72255173_72255368	0.06	Gm25939	predicted gene, 25939	262	0.86
chr2_168102539_168102698	0.06	AL831766.1	breast carcinoma amplified sequence 4 (BCAS4) pseudogene	12259	0.13
chr3_99187907_99188075	0.06	Gm18982	predicted gene, 18982	6710	0.13
chr12_58297089_58297242	0.06	Clec14a	C-type lectin domain family 14, member a	27875	0.24
chr17_80677489_80677679	0.06	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	26434	0.19
chr1_57391527_57391708	0.06	Tyw5	tRNA-yW synthesizing protein 5	123	0.95
chr11_107373329_107373545	0.06	Gm11712	predicted gene 11712	13546	0.13
chr8_93233702_93233868	0.06	Ces1e	carboxylesterase 1E	4166	0.16
chr8_106882742_106882961	0.06	Chtf8	CTF8, chromosome transmission fidelity factor 8	10364	0.12
chr7_126760516_126760683	0.06	Mapk3	mitogen-activated protein kinase 3	2	0.92
chr5_3488489_3488661	0.06	Gm17590	predicted gene, 17590	7702	0.13
chrX_120279500_120279651	0.06	Pcdh11x	protocadherin 11 X-linked	10684	0.2
chr3_121346684_121346853	0.06	Gm5711	predicted gene 5711	33911	0.12
chr5_130200757_130200925	0.06	Rabgef1	RAB guanine nucleotide exchange factor (GEF) 1	6212	0.1
chr3_63992313_63992468	0.06	Gmps	guanine monophosphate synthetase	16284	0.13
chr1_64308159_64308318	0.06	Gm28981	predicted gene 28981	5195	0.28
chr5_43788120_43788279	0.06	Gm43181	predicted gene 43181	2082	0.19
chr14_65357765_65357928	0.06	Zfp395	zinc finger protein 395	543	0.68
chr1_31046483_31046963	0.06	Gm28644	predicted gene 28644	4804	0.19
chr4_53280466_53280664	0.06	AI427809	expressed sequence AI427809	10333	0.18
chr15_73506117_73506298	0.06	Dennd3	DENN/MADD domain containing 3	6353	0.18
chr16_46131552_46131725	0.06	Cd96	CD96 antigen	11387	0.19
chr8_69063559_69063737	0.06	Slc18a1	solute carrier family 18 (vesicular monoamine), member 1	11860	0.15
chr4_49535372_49535819	0.06	Aldob	aldolase B, fructose-bisphosphate	3271	0.17
chr14_86309035_86309286	0.06	Gm23926	predicted gene, 23926	2218	0.22
chr5_112843602_112843780	0.06	Myo18b	myosin XVIIIb	27895	0.17
chr10_121316471_121316644	0.06	Tbc1d30	TBC1 domain family, member 30	5368	0.16
chr12_51709142_51709293	0.06	Strn3	striatin, calmodulin binding protein 3	17320	0.16
chr4_49542856_49543140	0.06	Aldob	aldolase B, fructose-bisphosphate	3112	0.18
chr8_76907164_76907353	0.06	Nr3c2	nuclear receptor subfamily 3, group C, member 2	1014	0.57
chr4_137772777_137772941	0.06	Alpl	alkaline phosphatase, liver/bone/kidney	3039	0.27
chr4_81591457_81591882	0.06	Gm11411	predicted gene 11411	104772	0.07
chr5_147894276_147894456	0.05	Slc46a3	solute carrier family 46, member 3	449	0.8
chr19_10664062_10664213	0.05	Vwce	von Willebrand factor C and EGF domains	6148	0.1
chr5_90457077_90457513	0.05	Alb	albumin	3602	0.2
chr19_8097849_8098000	0.05	Slc22a28	solute carrier family 22, member 28	34058	0.16
chr3_89143426_89143577	0.05	Pklr	pyruvate kinase liver and red blood cell	6878	0.07
chr7_140719940_140720091	0.05	Olfr542-ps1	olfactory receptor 542, pseudogene 1	1267	0.28
chr16_95432244_95432403	0.05	Erg	ETS transcription factor	26922	0.22
chr15_10375239_10375408	0.05	Agxt2	alanine-glyoxylate aminotransferase 2	16744	0.19
chr11_16845424_16845700	0.05	Egfros	epidermal growth factor receptor, opposite strand	14860	0.2
chr16_95459306_95459486	0.05	Erg	ETS transcription factor	48	0.99
chr10_93282645_93282796	0.05	Elk3	ELK3, member of ETS oncogene family	28091	0.14
chr13_114392779_114392930	0.05	Ndufs4	NADH:ubiquinone oxidoreductase core subunit S4	4596	0.21
chr5_139384486_139384856	0.05	Gpr146	G protein-coupled receptor 146	4090	0.13
chr14_37027574_37027733	0.05	Gm47885	predicted gene, 47885	3119	0.2
chr8_69112104_69112255	0.05	Atp6v1b2	ATPase, H+ transporting, lysosomal V1 subunit B2	9051	0.16
chr15_75596455_75596620	0.05	Gpihbp1	GPI-anchored HDL-binding protein 1	91	0.95
chr17_45567292_45567749	0.05	Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	2216	0.14
chr3_114294859_114295010	0.05	Col11a1	collagen, type XI, alpha 1	129656	0.06
chr17_31474403_31474582	0.05	Pde9a	phosphodiesterase 9A	3440	0.12
chr4_150576385_150576576	0.05	Rere	arginine glutamic acid dipeptide (RE) repeats	6823	0.21
chr6_5473962_5474316	0.05	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	22122	0.24
chr5_107120720_107120871	0.05	Tgfbr3	transforming growth factor, beta receptor III	12128	0.16
chr8_126847749_126848310	0.05	A630001O12Rik	RIKEN cDNA A630001O12 gene	8796	0.2
chr13_35016383_35016558	0.05	Eci2	enoyl-Coenzyme A delta isomerase 2	10624	0.12
chr4_6539560_6539735	0.05	Gm11801	predicted gene 11801	86	0.98
chr6_149359539_149359690	0.05	Gm15784	predicted gene 15784	2072	0.23
chr7_73478544_73478710	0.05	Chd2	chromodomain helicase DNA binding protein 2	201	0.91
chr2_103870054_103870389	0.05	Gm13876	predicted gene 13876	18103	0.09
chr3_94512708_94512862	0.05	Snx27	sorting nexin family member 27	6306	0.09
chr5_100368600_100368758	0.05	Sec31a	Sec31 homolog A (S. cerevisiae)	4409	0.19
chr2_155539663_155540189	0.05	Mipep-ps	mitochondrial intermediate peptidase, pseudogene	2721	0.13
chr13_25791444_25791595	0.05	Gm11350	predicted gene 11350	110376	0.07
chr3_18877716_18877898	0.05	Gm30341	predicted gene, 30341	124730	0.06
chr8_115089778_115090403	0.05	Gm22556	predicted gene, 22556	37177	0.23
chr1_173599258_173599409	0.05	Ifi213	interferon activated gene 213	59	0.97
chr2_96253373_96253545	0.05	Lrrc4c	leucine rich repeat containing 4C	64710	0.14
chr1_173491252_173491410	0.05	Ifi206	interferon activated gene 206	290	0.89
chr6_128522025_128522231	0.05	Pzp	PZP, alpha-2-macroglobulin like	4575	0.11
chr1_136441030_136441213	0.05	Ddx59	DEAD (Asp-Glu-Ala-Asp) box polypeptide 59	8719	0.15
chr1_54850108_54850451	0.05	Ankrd44	ankyrin repeat domain 44	34432	0.16
chr2_102694561_102694718	0.05	Slc1a2	solute carrier family 1 (glial high affinity glutamate transporter), member 2	11717	0.23
chr13_24945328_24945479	0.05	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	2251	0.21
chr4_144977157_144977352	0.05	Vps13d	vacuolar protein sorting 13D	6707	0.21
chr16_91434651_91434809	0.05	Gm46562	predicted gene, 46562	23691	0.08
chr15_62529162_62529323	0.05	Gm41333	predicted gene, 41333	38733	0.21
chr18_5091846_5091997	0.05	Svil	supervillin	2460	0.4
chr13_44890716_44890885	0.05	Jarid2	jumonji, AT rich interactive domain 2	50017	0.13
chr18_39357013_39357188	0.05	Arhgap26	Rho GTPase activating protein 26	5483	0.2
chr12_41081814_41082149	0.05	Immp2l	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	13669	0.21
chr10_26828824_26829011	0.05	Arhgap18	Rho GTPase activating protein 18	6315	0.25
chr15_43702286_43702631	0.05	Gm2140	predicted gene 2140	106003	0.07
chr17_46031864_46032231	0.05	Vegfa	vascular endothelial growth factor A	232	0.92
chr18_10413650_10413816	0.05	Greb1l	growth regulation by estrogen in breast cancer-like	44492	0.12
chr11_50175754_50175938	0.05	Mrnip	MRN complex interacting protein	939	0.42
chrX_84312323_84312721	0.05	Dmd	dystrophin, muscular dystrophy	235873	0.02
chr5_100371529_100371680	0.05	Sec31a	Sec31 homolog A (S. cerevisiae)	1880	0.3
chr15_55245352_55245503	0.05	Gm26296	predicted gene, 26296	17176	0.21
chr4_141161528_141161683	0.05	Fbxo42	F-box protein 42	13683	0.11
chr13_72293404_72293565	0.05	Gm4052	predicted gene 4052	56737	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Total log-likelihood	Term	Description
0.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.1	GO:0000189	MAPK import into nucleus(GO:0000189)
0.1	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.0	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	GO:0097487	multivesicular body, internal vesicle(GO:0097487)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.1	GO:0070538	oleic acid binding(GO:0070538)
0.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening

Results for Sox5_Sry

Z-value: 0.46

Motif logo

Transcription factors associated with Sox5_Sry

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox5_Sry motif across conditions

Conditions sorted by the z-value of the Sox5_Sry motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox5_Sry

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: