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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Sox6_Sox9

Z-value: 1.72

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Transcription factors associated with Sox6_Sox9

Gene Symbol	Gene ID	Gene Info
Sox6 Ensembl NCBI MGI UniProt	ENSMUSG00000051910.7	SRY (sex determining region Y)-box 6
Sox9 Ensembl NCBI MGI UniProt	ENSMUSG00000000567.5	SRY (sex determining region Y)-box 9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr7_115576330_115576481	Sox6	21491	0.280207	-0.92	1.0e-02	Click!
chr7_115731752_115731939	Sox6	69480	0.131585	-0.89	1.7e-02	Click!
chr7_115644077_115644258	Sox6	18198	0.288844	-0.87	2.5e-02	Click!
chr7_115661755_115661917	Sox6	529	0.877130	-0.82	4.5e-02	Click!
chr7_115857826_115857977	Sox6	1951	0.461715	-0.82	4.6e-02	Click!
chr11_112788056_112788236	Sox9	5922	0.187637	0.88	2.2e-02	Click!
chr11_112783351_112783652	Sox9	1277	0.363013	0.74	9.1e-02	Click!
chr11_112788385_112788735	Sox9	6336	0.185303	0.71	1.1e-01	Click!
chr11_112782073_112782233	Sox9	71	0.650859	0.56	2.5e-01	Click!

Activity of the Sox6_Sox9 motif across conditions

Conditions sorted by the z-value of the Sox6_Sox9 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr13_93624884_93625040	1.49	Gm15622	predicted gene 15622	420	0.81
chr5_8968601_8968752	1.46	Gm15610	predicted gene 15610	3272	0.16
chr10_85161408_85161709	1.05	Cry1	cryptochrome 1 (photolyase-like)	10202	0.18
chr4_60659551_60660018	0.99	Mup11	major urinary protein 11	46	0.97
chr4_60418315_60418583	0.91	Mup9	major urinary protein 9	2135	0.24
chr9_104461716_104461890	0.90	Gm25904	predicted gene, 25904	19707	0.19
chr4_60498312_60498676	0.88	Mup1	major urinary protein 1	838	0.49
chr4_60066787_60066938	0.84	Mup7	major urinary protein 7	3549	0.22
chr13_93625562_93625714	0.80	Gm15622	predicted gene 15622	256	0.91
chr5_8964466_8964675	0.76	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	6018	0.13
chr4_60218940_60219116	0.73	Mup8	major urinary protein 8	3552	0.23
chr11_28906435_28906594	0.72	Efemp1	epidermal growth factor-containing fibulin-like extracellular matrix protein 1	9153	0.23
chr6_129215204_129215355	0.66	2310001H17Rik	RIKEN cDNA 2310001H17 gene	18695	0.1
chr3_85858327_85858483	0.66	Gm37240	predicted gene, 37240	28963	0.1
chr3_83023876_83024027	0.63	Fga	fibrinogen alpha chain	2125	0.24
chr18_20974221_20974372	0.63	Rnf125	ring finger protein 125	12824	0.2
chr10_8122314_8122465	0.62	Gm30906	predicted gene, 30906	53742	0.15
chr5_9047464_9048021	0.62	Gm40264	predicted gene, 40264	12618	0.15
chr9_65334133_65334359	0.61	Gm39363	predicted gene, 39363	1726	0.18
chr10_84418574_84418728	0.61	Nuak1	NUAK family, SNF1-like kinase, 1	21946	0.15
chr5_8961694_8961940	0.61	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	3265	0.17
chr19_41334643_41334794	0.61	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	50378	0.14
chr8_11308621_11308772	0.60	Col4a1	collagen, type IV, alpha 1	3993	0.18
chr1_58170640_58170791	0.60	Aox3	aldehyde oxidase 3	1091	0.5
chr14_37027574_37027733	0.60	Gm47885	predicted gene, 47885	3119	0.2
chr7_101479062_101479229	0.56	Pde2a	phosphodiesterase 2A, cGMP-stimulated	2140	0.23
chr2_115520314_115520525	0.54	3110099E03Rik	RIKEN cDNA 3110099E03 gene	7325	0.25
chr12_8643417_8643595	0.54	Pum2	pumilio RNA-binding family member 2	30628	0.17
chr6_54842890_54843041	0.54	Znrf2	zinc and ring finger 2	25517	0.18
chr19_3669127_3669720	0.51	Lrp5	low density lipoprotein receptor-related protein 5	17133	0.12
chr18_20984644_20984795	0.51	Rnf138	ring finger protein 138	16622	0.19
chr11_59965854_59966027	0.50	Rasd1	RAS, dexamethasone-induced 1	996	0.42
chr8_27233050_27233201	0.50	Gm45470	predicted gene 45470	747	0.48
chr14_40949121_40949299	0.50	Tspan14	tetraspanin 14	14889	0.18
chr10_12816564_12816741	0.50	Utrn	utrophin	3037	0.26
chrX_169863890_169864041	0.49	Mid1	midline 1	15657	0.24
chr11_112217336_112217487	0.49	Gm11680	predicted gene 11680	109973	0.07
chr1_88975960_88976113	0.49	1700067G17Rik	RIKEN cDNA 1700067G17 gene	40077	0.14
chr5_117361300_117361465	0.48	Wsb2	WD repeat and SOCS box-containing 2	360	0.77
chr1_180219918_180220099	0.48	Gm37336	predicted gene, 37336	7607	0.14
chr14_30908290_30908855	0.48	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	5557	0.12
chr8_36723231_36723557	0.48	Dlc1	deleted in liver cancer 1	9660	0.29
chr3_18064935_18065086	0.48	Gm23726	predicted gene, 23726	4316	0.23
chr13_93618232_93618425	0.48	Gm15622	predicted gene 15622	7054	0.17
chr10_93506452_93506730	0.47	Hal	histidine ammonia lyase	5466	0.15
chr13_36466242_36466419	0.47	Gm48763	predicted gene, 48763	7050	0.24
chr11_72281229_72281388	0.47	n-R5s70	nuclear encoded rRNA 5S 70	292	0.83
chr9_105759000_105759170	0.46	Gm38314	predicted gene, 38314	31300	0.16
chr6_72633856_72634007	0.46	Gm15401	predicted gene 15401	2322	0.13
chr9_65333970_65334121	0.46	Gm39363	predicted gene, 39363	1525	0.2
chr17_75432717_75432868	0.46	Rasgrp3	RAS, guanyl releasing protein 3	3104	0.34
chrX_13275902_13276062	0.46	Ddx3x	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked	4988	0.14
chr5_28003991_28004186	0.46	Gm4865	predicted gene 4865	2782	0.24
chr14_8248346_8248505	0.45	Acox2	acyl-Coenzyme A oxidase 2, branched chain	1995	0.33
chr10_85193452_85193650	0.45	Cry1	cryptochrome 1 (photolyase-like)	8487	0.2
chr18_20931708_20931938	0.45	Rnf125	ring finger protein 125	12802	0.2
chr13_43500025_43500247	0.45	Gm47683	predicted gene, 47683	31	0.97
chr15_10960635_10960786	0.45	C1qtnf3	C1q and tumor necrosis factor related protein 3	8353	0.15
chr18_46725311_46725732	0.45	Cdo1	cysteine dioxygenase 1, cytosolic	2508	0.19
chr2_12382524_12382675	0.44	Mindy3	MINDY lysine 48 deubiquitinase 3	4182	0.17
chr5_139938836_139939133	0.44	Gm43704	predicted gene 43704	24807	0.14
chr3_133765600_133766533	0.44	Gm6135	prediticted gene 6135	25438	0.2
chr14_22587357_22587508	0.44	Lrmda	leucine rich melanocyte differentiation associated	9081	0.23
chr17_49349587_49349761	0.44	Gm18067	predicted gene, 18067	18178	0.18
chr19_33098344_33098549	0.43	Gm29946	predicted gene, 29946	24201	0.18
chr10_93497397_93497600	0.43	Hal	histidine ammonia lyase	1093	0.43
chr10_45017413_45017609	0.43	Gm40639	predicted gene, 40639	6791	0.17
chr19_36623611_36623788	0.43	Hectd2os	Hectd2, opposite strand	2305	0.33
chr15_27564431_27564740	0.43	Ank	progressive ankylosis	6862	0.17
chr5_150227882_150228033	0.42	Gm36378	predicted gene, 36378	15906	0.19
chr16_31165540_31165735	0.42	Gm18237	predicted gene, 18237	7767	0.18
chr2_3683170_3683338	0.42	Gm13183	predicted gene 13183	2664	0.22
chr10_8133800_8133951	0.42	Gm30906	predicted gene, 30906	42256	0.18
chr5_145854968_145855207	0.42	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	21604	0.14
chr4_126097782_126097933	0.42	Lsm10	U7 snRNP-specific Sm-like protein LSM10	1197	0.32
chr12_21167471_21167660	0.42	Asap2	ArfGAP with SH3 domain, ankyrin repeat and PH domain 2	55611	0.1
chr16_48767631_48767807	0.41	Trat1	T cell receptor associated transmembrane adaptor 1	4237	0.22
chr10_8007720_8007891	0.41	Gm48614	predicted gene, 48614	13487	0.22
chr10_59972679_59972846	0.41	Anapc16	anaphase promoting complex subunit 16	17621	0.15
chr4_117682570_117682721	0.41	Dmap1	DNA methyltransferase 1-associated protein 1	372	0.82
chr15_7088669_7089236	0.41	Lifr	LIF receptor alpha	1662	0.5
chr13_114466635_114466797	0.41	Fst	follistatin	7765	0.16
chr13_101895557_101895722	0.41	Gm17832	predicted gene, 17832	24781	0.19
chr4_135962366_135962540	0.41	Gale	galactose-4-epimerase, UDP	1274	0.24
chr19_30096271_30096642	0.40	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	4495	0.24
chr8_120419577_120419740	0.40	Gm22715	predicted gene, 22715	23891	0.17
chr11_96934737_96934922	0.40	Prr15l	proline rich 15-like	3442	0.11
chr8_70224924_70225098	0.39	Armc6	armadillo repeat containing 6	166	0.91
chr11_53307549_53307709	0.39	Hspa4	heat shock protein 4	7172	0.15
chr14_75795151_75795306	0.39	Slc25a30	solute carrier family 25, member 30	8191	0.15
chr2_5609208_5609400	0.39	Gm13216	predicted gene 13216	5733	0.28
chr11_49267629_49267816	0.38	Olfr1393	olfactory receptor 1393	10582	0.11
chr2_132863556_132863823	0.38	Crls1	cardiolipin synthase 1	15951	0.12
chr18_32254065_32254257	0.38	Ercc3	excision repair cross-complementing rodent repair deficiency, complementation group 3	3108	0.27
chr10_24106562_24106716	0.37	Taar9	trace amine-associated receptor 9	2895	0.13
chr4_32561294_32561627	0.37	Bach2os	BTB and CNC homology 2, opposite strand	10157	0.16
chr15_3353815_3354005	0.37	Ccdc152	coiled-coil domain containing 152	50384	0.15
chr8_33853619_33853844	0.37	Rbpms	RNA binding protein gene with multiple splicing	58	0.97
chr13_28507894_28508045	0.37	Gm6081	predicted gene 6081	3263	0.28
chr19_46975101_46975486	0.37	Nt5c2	5'-nucleotidase, cytosolic II	5725	0.17
chr6_108136848_108136999	0.37	Rpl36-ps12	ribosomal protein L36, pseudogene 12	3586	0.26
chr19_21012514_21012680	0.37	Tmc1	transmembrane channel-like gene family 1	58395	0.13
chr4_61949215_61949401	0.37	Mup-ps19	major urinary protein, pseudogene 19	10603	0.17
chr3_81663585_81663896	0.37	Gm43346	predicted gene 43346	57936	0.14
chr11_20934751_20935121	0.36	Gm23681	predicted gene, 23681	2765	0.31
chr19_33099137_33099698	0.36	Gm29946	predicted gene, 29946	23230	0.18
chr19_30151607_30151827	0.36	Gldc	glycine decarboxylase	6486	0.2
chr18_31936613_31936956	0.36	Lims2	LIM and senescent cell antigen like domains 2	492	0.73
chr10_84803969_84804150	0.36	Gm24226	predicted gene, 24226	7124	0.23
chr2_152397803_152397979	0.36	Sox12	SRY (sex determining region Y)-box 12	155	0.89
chr5_9032498_9032725	0.36	Gm40264	predicted gene, 40264	2169	0.24
chr5_89322164_89322355	0.35	Gc	vitamin D binding protein	113369	0.07
chr13_38626107_38626269	0.35	Gm47400	predicted gene, 47400	8783	0.14
chr17_84997546_84997697	0.35	Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	3941	0.22
chr6_121850527_121851087	0.35	Mug1	murinoglobulin 1	9703	0.21
chr11_59514377_59514532	0.35	4933439C10Rik	RIKEN cDNA 4933439C10 gene	6813	0.1
chr6_129539224_129539435	0.35	Gm44243	predicted gene, 44243	892	0.35
chr13_47154962_47155118	0.35	Gm48581	predicted gene, 48581	32	0.97
chr8_94070045_94070216	0.35	Bbs2	Bardet-Biedl syndrome 2 (human)	83	0.95
chr9_77845751_77846338	0.35	Gm19572	predicted gene, 19572	5664	0.15
chr10_59205891_59206053	0.35	Gm23223	predicted gene, 23223	10273	0.15
chr11_90269750_90269901	0.35	Mmd	monocyte to macrophage differentiation-associated	20349	0.21
chr15_36432237_36432390	0.34	Gm49224	predicted gene, 49224	4378	0.18
chr17_15341268_15341498	0.34	Gm7423	predicted gene 7423	19501	0.14
chr7_87222899_87223055	0.34	Gm6230	predicted gene 6230	19908	0.21
chr14_68458990_68459141	0.34	Gm31227	predicted gene, 31227	2566	0.36
chr9_4372230_4372403	0.34	Gm23992	predicted gene, 23992	981	0.54
chr12_85366293_85366504	0.34	Gm47817	predicted gene, 47817	2753	0.16
chr2_72881753_72881905	0.34	Sp3	trans-acting transcription factor 3	59255	0.1
chr13_37944290_37944811	0.33	Rreb1	ras responsive element binding protein 1	2466	0.3
chr5_126566218_126566538	0.33	Gm24839	predicted gene, 24839	52397	0.14
chr4_144977157_144977352	0.33	Vps13d	vacuolar protein sorting 13D	6707	0.21
chr8_119436291_119436442	0.33	Osgin1	oxidative stress induced growth inhibitor 1	752	0.59
chr19_29796308_29796471	0.33	9930021J03Rik	RIKEN cDNA 9930021J03 gene	9118	0.17
chr1_82202782_82202972	0.33	Gm9747	predicted gene 9747	30235	0.18
chr15_55252499_55252656	0.33	Gm26296	predicted gene, 26296	10026	0.23
chr13_94143352_94143530	0.33	Gm15907	predicted gene 15907	3324	0.24
chr16_20102189_20102498	0.33	Klhl24	kelch-like 24	4751	0.22
chr4_149978768_149979375	0.33	H6pd	hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)	22194	0.13
chr8_106882742_106882961	0.33	Chtf8	CTF8, chromosome transmission fidelity factor 8	10364	0.12
chr17_84987973_84988377	0.33	Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	5498	0.2
chr15_66911263_66911477	0.33	Ccn4	cellular communication network factor 4	2059	0.29
chr19_36534453_36534632	0.33	Hectd2	HECT domain E3 ubiquitin protein ligase 2	20097	0.2
chr3_107687032_107687196	0.32	Ahcyl1	S-adenosylhomocysteine hydrolase-like 1	8849	0.16
chr1_74344854_74345034	0.32	Pnkd	paroxysmal nonkinesiogenic dyskinesia	12281	0.09
chr8_126754096_126754268	0.32	Gm45805	predicted gene 45805	4152	0.29
chr4_135741644_135741824	0.32	Il22ra1	interleukin 22 receptor, alpha 1	13562	0.12
chr18_65921955_65922109	0.32	Gm50118	predicted gene, 50118	175	0.88
chr17_29282347_29282498	0.32	BC004004	cDNA sequence BC004004	5740	0.11
chr5_146232349_146232681	0.32	Cdk8	cyclin-dependent kinase 8	1130	0.35
chr15_75596455_75596620	0.32	Gpihbp1	GPI-anchored HDL-binding protein 1	91	0.95
chr5_8962552_8962757	0.32	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	4102	0.15
chr4_11896333_11896507	0.32	Gm25002	predicted gene, 25002	52467	0.11
chr6_4926913_4927078	0.32	Gm26814	predicted gene, 26814	15152	0.13
chr6_85262797_85262970	0.31	Sfxn5	sideroflexin 5	2050	0.29
chr7_46840442_46840768	0.31	Ldha	lactate dehydrogenase A	870	0.39
chr13_110421353_110421528	0.31	Plk2	polo like kinase 2	23643	0.22
chr8_86690399_86690763	0.31	Gm22305	predicted gene, 22305	19238	0.15
chr7_130523668_130523823	0.31	Gm4275	predicted gene 4275	10	0.96
chr11_86995694_86995863	0.31	Gm22387	predicted gene, 22387	1485	0.32
chr4_114958381_114958568	0.31	Cmpk1	cytidine monophosphate (UMP-CMP) kinase 1	28598	0.11
chr16_22914452_22914638	0.31	Fetub	fetuin beta	3789	0.14
chr15_79323545_79323705	0.31	Pla2g6	phospholipase A2, group VI	59	0.95
chr2_64973925_64974085	0.31	Grb14	growth factor receptor bound protein 14	1741	0.5
chr11_108846353_108846520	0.31	Cep112it	centrosomal protein 112, intronic transcript	26103	0.19
chr11_106053420_106053645	0.31	Gm11646	predicted gene 11646	1680	0.21
chr16_91828588_91828869	0.31	Itsn1	intersectin 1 (SH3 domain protein 1A)	1191	0.47
chr6_42251414_42251583	0.31	Gstk1	glutathione S-transferase kappa 1	5475	0.12
chr14_66748215_66748366	0.31	Gm10032	predicted gene 10032	36190	0.15
chr7_126260333_126260533	0.31	Sbk1	SH3-binding kinase 1	11571	0.11
chr6_122174213_122174364	0.30	Mug-ps1	murinoglobulin, pseudogene 1	1727	0.34
chr18_65075884_65076295	0.30	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	57	0.98
chr7_114582552_114582724	0.30	Cyp2r1	cytochrome P450, family 2, subfamily r, polypeptide 1	19666	0.19
chr9_69314244_69314596	0.30	Rora	RAR-related orphan receptor alpha	24738	0.18
chr10_77061077_77061274	0.30	Col18a1	collagen, type XVIII, alpha 1	1178	0.41
chr14_70699508_70699766	0.30	Xpo7	exportin 7	8398	0.15
chr8_10899350_10899661	0.30	4833411C07Rik	RIKEN cDNA 4833411C07 gene	417	0.64
chr2_103846371_103846545	0.30	Gm13879	predicted gene 13879	2802	0.12
chr11_4986459_4986642	0.30	Ap1b1	adaptor protein complex AP-1, beta 1 subunit	274	0.88
chr6_37748273_37748424	0.29	Atp6v0c-ps2	ATPase, H+ transporting, lysosomal V0 subunit C, pseudogene 2	57738	0.12
chr4_33250016_33250167	0.29	Pnrc1	proline-rich nuclear receptor coactivator 1	1581	0.35
chr4_150748175_150748630	0.29	Gm16079	predicted gene 16079	69610	0.08
chr5_93008624_93008788	0.29	Gm25521	predicted gene, 25521	4433	0.16
chr2_103834210_103834381	0.29	Gm13877	predicted gene 13877	3222	0.11
chr6_97871999_97872401	0.29	Gm15531	predicted gene 15531	18339	0.23
chr11_16704048_16704199	0.29	Gm25698	predicted gene, 25698	28588	0.15
chr2_167727310_167727515	0.29	A530013C23Rik	RIKEN cDNA A530013C23 gene	36231	0.09
chr1_59176886_59177061	0.29	Mpp4	membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)	13584	0.12
chr12_54946386_54946548	0.29	Baz1a	bromodomain adjacent to zinc finger domain 1A	2415	0.21
chr5_137975596_137975772	0.29	Azgp1	alpha-2-glycoprotein 1, zinc	5836	0.09
chr19_46132112_46132476	0.29	Elovl3	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3	397	0.76
chr5_107413821_107414114	0.29	Ephx4	epoxide hydrolase 4	8182	0.1
chr12_26460028_26460238	0.29	Rsad2	radical S-adenosyl methionine domain containing 2	3681	0.17
chr19_21077803_21077989	0.29	4930554I06Rik	RIKEN cDNA 4930554I06 gene	26606	0.21
chr15_10872191_10872614	0.29	Gm29742	predicted gene, 29742	45035	0.12
chr15_39852629_39852953	0.28	Dpys	dihydropyrimidinase	4676	0.25
chr18_64755884_64756035	0.28	Gm23016	predicted gene, 23016	27893	0.12
chrX_167229521_167229672	0.28	Tmsb4x	thymosin, beta 4, X chromosome	20281	0.17
chr17_57231348_57231526	0.28	C3	complement component 3	3301	0.14
chr2_126584960_126585111	0.28	Hdc	histidine decarboxylase	13226	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox6_Sox9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0045472	response to ether(GO:0045472)
0.1	0.7	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.1	0.4	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.4	GO:2000850	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1	0.6	GO:0009115	xanthine catabolic process(GO:0009115)
0.1	0.3	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.1	0.4	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.1	0.5	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.3	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.1	0.2	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.2	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.5	GO:2001046	positive regulation of integrin-mediated signaling pathway(GO:2001046)
0.1	0.3	GO:0010792	DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1	0.4	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1	0.2	GO:0030242	pexophagy(GO:0030242)
0.1	0.8	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.1	0.3	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.1	0.2	GO:0006393	termination of mitochondrial transcription(GO:0006393)
0.1	0.4	GO:0033152	immunoglobulin V(D)J recombination(GO:0033152)
0.1	0.4	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1	0.2	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.1	0.2	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.1	0.2	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.1	0.2	GO:0035984	response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.1	0.3	GO:0097466	glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.4	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0015772	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.2	GO:0019660	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.1	GO:0033499	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.2	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.0	GO:0014858	positive regulation of skeletal muscle cell proliferation(GO:0014858)
0.0	0.1	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.1	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:2001171	positive regulation of ATP biosynthetic process(GO:2001171)
0.0	0.1	GO:1900104	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.2	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.1	GO:0051410	detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.0	0.1	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.4	GO:0007097	nuclear migration(GO:0007097)
0.0	0.1	GO:0021775	smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.1	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.3	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.0	GO:0060686	negative regulation of prostatic bud formation(GO:0060686)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0006432	phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0	0.5	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.1	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.1	GO:0015746	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.0	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.3	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.2	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0009597	detection of virus(GO:0009597)
0.0	0.2	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.2	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0014873	response to muscle activity involved in regulation of muscle adaptation(GO:0014873)
0.0	0.1	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.2	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0002282	microglial cell activation involved in immune response(GO:0002282)
0.0	0.2	GO:0035878	nail development(GO:0035878)
0.0	0.1	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.1	GO:0071638	negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0	0.1	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0034729	histone H3-K79 methylation(GO:0034729)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0097094	craniofacial suture morphogenesis(GO:0097094)
0.0	0.1	GO:0001983	baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.0	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0034443	negative regulation of lipoprotein oxidation(GO:0034443)
0.0	0.1	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.0	0.2	GO:0019441	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.2	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.1	GO:0060005	vestibular reflex(GO:0060005)
0.0	0.1	GO:0051835	positive regulation of synapse structural plasticity(GO:0051835)
0.0	0.1	GO:0015888	thiamine transport(GO:0015888)
0.0	0.2	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.1	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0036444	calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.0	GO:0019401	alditol biosynthetic process(GO:0019401)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.2	GO:1903975	regulation of glial cell migration(GO:1903975)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.0	GO:0046078	pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.2	GO:0014857	regulation of skeletal muscle cell proliferation(GO:0014857)
0.0	0.1	GO:0045820	negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0	0.0	GO:0009448	gamma-aminobutyric acid metabolic process(GO:0009448)
0.0	0.2	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.2	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0002606	positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.1	GO:0014045	establishment of endothelial blood-brain barrier(GO:0014045)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.0	GO:0060585	regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0	0.2	GO:0007175	negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0	0.0	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.0	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.1	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.1	GO:0071503	response to heparin(GO:0071503) cellular response to heparin(GO:0071504)
0.0	0.1	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.2	GO:0035999	tetrahydrofolate interconversion(GO:0035999)
0.0	0.1	GO:0033015	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.2	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.0	GO:0006975	DNA damage induced protein phosphorylation(GO:0006975)
0.0	0.1	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.1	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0	0.1	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.0	0.1	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:0046836	glycolipid transport(GO:0046836)
0.0	0.0	GO:0010693	negative regulation of alkaline phosphatase activity(GO:0010693)
0.0	0.1	GO:1902969	mitotic DNA replication(GO:1902969)
0.0	0.1	GO:1904714	regulation of chaperone-mediated autophagy(GO:1904714)
0.0	0.1	GO:0070350	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.1	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0007217	tachykinin receptor signaling pathway(GO:0007217)
0.0	0.0	GO:0060762	regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0	0.0	GO:0090292	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.0	0.1	GO:1903376	neuron intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0036480) regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903376)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.0	GO:0072095	regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0	0.1	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0051798	positive regulation of hair follicle development(GO:0051798)
0.0	0.1	GO:2001187	positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0	0.0	GO:0006145	purine nucleobase catabolic process(GO:0006145)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.1	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0	0.2	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.0	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0042256	mature ribosome assembly(GO:0042256)
0.0	0.1	GO:0007412	axon target recognition(GO:0007412)
0.0	0.2	GO:0033683	nucleotide-excision repair, DNA incision(GO:0033683)
0.0	0.1	GO:0048242	epinephrine secretion(GO:0048242)
0.0	0.1	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.0	GO:0002930	trabecular meshwork development(GO:0002930)
0.0	0.0	GO:1902268	negative regulation of polyamine transmembrane transport(GO:1902268)
0.0	0.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.0	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.1	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.0	GO:0071351	cellular response to interleukin-18(GO:0071351)
0.0	0.0	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.0	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:1900262	regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0	0.0	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.1	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.0	0.0	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.0	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.1	GO:0015722	canalicular bile acid transport(GO:0015722)
0.0	0.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:0072610	interleukin-12 secretion(GO:0072610)
0.0	0.0	GO:2000553	positive regulation of T-helper 2 cell cytokine production(GO:2000553)
0.0	0.1	GO:0044341	sodium-dependent phosphate transport(GO:0044341)
0.0	0.0	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.1	GO:0030917	midbrain-hindbrain boundary development(GO:0030917)
0.0	0.1	GO:0035507	regulation of myosin-light-chain-phosphatase activity(GO:0035507)
0.0	0.0	GO:0002378	immunoglobulin biosynthetic process(GO:0002378)
0.0	0.1	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.0	GO:0003072	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0	0.1	GO:0014816	skeletal muscle satellite cell differentiation(GO:0014816)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0	0.2	GO:0001886	endothelial cell morphogenesis(GO:0001886)
0.0	0.0	GO:0001767	establishment of lymphocyte polarity(GO:0001767) establishment of T cell polarity(GO:0001768)
0.0	0.2	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.1	GO:0006398	mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0	0.0	GO:0001998	angiotensin mediated vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001998)
0.0	0.0	GO:1904468	negative regulation of tumor necrosis factor secretion(GO:1904468)
0.0	0.0	GO:0021586	pons maturation(GO:0021586)
0.0	0.1	GO:0051596	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.0	GO:2000053	regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.0	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0006817	phosphate ion transport(GO:0006817)
0.0	0.0	GO:0002752	cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.0	0.0	GO:0090360	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.1	GO:1900042	positive regulation of interleukin-2 secretion(GO:1900042)
0.0	0.0	GO:0044336	canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0	0.0	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.0	GO:0046985	positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0070900	mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.0	0.2	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:0033505	floor plate morphogenesis(GO:0033505)
0.0	0.0	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.0	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0001920	negative regulation of receptor recycling(GO:0001920)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:1903352	ornithine transport(GO:0015822) L-ornithine transmembrane transport(GO:1903352)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.0	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.0	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0	0.0	GO:1903232	melanosome assembly(GO:1903232)
0.0	0.0	GO:0044333	Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0	0.1	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.1	GO:0070431	nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.0	GO:0042427	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.1	GO:0016188	synaptic vesicle maturation(GO:0016188)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0035927	RNA import into mitochondrion(GO:0035927)
0.0	0.0	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.0	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.0	GO:0015712	hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0	0.1	GO:0050812	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0	0.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.0	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.0	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.0	0.0	GO:0002220	innate immune response activating cell surface receptor signaling pathway(GO:0002220)
0.0	0.1	GO:1901678	iron coordination entity transport(GO:1901678)
0.0	0.0	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.2	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.0	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.0	GO:0048539	bone marrow development(GO:0048539)
0.0	0.0	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.6	GO:0007566	embryo implantation(GO:0007566)
0.0	0.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.0	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.0	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.0	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.0	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.0	0.0	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.1	GO:1902474	positive regulation of protein localization to synapse(GO:1902474)
0.0	0.1	GO:0048199	vesicle targeting, to, from or within Golgi(GO:0048199)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0061511	centriole elongation(GO:0061511)
0.0	0.0	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0	0.0	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.0	GO:0033504	floor plate development(GO:0033504)
0.0	0.1	GO:1904153	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.0	GO:2000551	regulation of T-helper 2 cell cytokine production(GO:2000551)
0.0	0.0	GO:1902416	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0097368	establishment of Sertoli cell barrier(GO:0097368)
0.0	0.1	GO:0010388	cullin deneddylation(GO:0010388)
0.0	0.0	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.0	GO:0002322	B cell proliferation involved in immune response(GO:0002322)
0.0	0.0	GO:0002894	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.0	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.0	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0021830	interneuron migration from the subpallium to the cortex(GO:0021830)
0.0	0.0	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
0.0	0.0	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.1	GO:0042790	transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:0042790)
0.0	0.5	GO:0051865	protein autoubiquitination(GO:0051865)
0.0	0.0	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.1	GO:0010614	negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0	0.1	GO:0006527	arginine catabolic process(GO:0006527)
0.0	0.0	GO:1904667	negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.2	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.1	GO:0042270	protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0	0.0	GO:0072076	nephrogenic mesenchyme development(GO:0072076)
0.0	0.1	GO:0034030	nucleoside bisphosphate biosynthetic process(GO:0033866) ribonucleoside bisphosphate biosynthetic process(GO:0034030) purine nucleoside bisphosphate biosynthetic process(GO:0034033)
0.0	0.0	GO:0043970	histone H3-K9 acetylation(GO:0043970)
0.0	0.0	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.0	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.0	0.0	GO:0002331	pre-B cell allelic exclusion(GO:0002331)
0.0	0.0	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:1901223	negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0	0.1	GO:0006610	ribosomal protein import into nucleus(GO:0006610)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.3	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.1	0.3	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1	0.5	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0044322	endoplasmic reticulum quality control compartment(GO:0044322)
0.0	0.2	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.2	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.3	GO:0034464	BBSome(GO:0034464)
0.0	0.2	GO:0005683	U7 snRNP(GO:0005683)
0.0	0.1	GO:0000811	GINS complex(GO:0000811)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.2	GO:0034366	spherical high-density lipoprotein particle(GO:0034366)
0.0	0.1	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.4	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.5	GO:1902562	NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.0	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.3	GO:0045120	pronucleus(GO:0045120)
0.0	0.2	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.3	GO:0016010	dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.1	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.2	GO:0034364	high-density lipoprotein particle(GO:0034364)
0.0	0.2	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:1990423	RZZ complex(GO:1990423)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0072559	NLRP3 inflammasome complex(GO:0072559)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.1	GO:0070847	core mediator complex(GO:0070847)
0.0	0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.0	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.0	GO:0000322	storage vacuole(GO:0000322)
0.0	0.0	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:0005852	eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.0	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0005796	Golgi lumen(GO:0005796)
0.0	0.1	GO:0000235	astral microtubule(GO:0000235)
0.0	0.3	GO:0035861	site of double-strand break(GO:0035861)
0.0	0.0	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.0	GO:0017133	mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0	0.0	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.0	GO:0008091	spectrin(GO:0008091)
0.0	0.1	GO:0030485	smooth muscle contractile fiber(GO:0030485)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.6	GO:0016726	xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1	0.3	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.7	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.1	0.5	GO:0035473	lipase binding(GO:0035473)
0.1	0.3	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1	0.3	GO:0070878	primary miRNA binding(GO:0070878)
0.1	0.2	GO:0016880	acid-ammonia (or amide) ligase activity(GO:0016880)
0.1	0.1	GO:0008905	mannose-phosphate guanylyltransferase activity(GO:0008905)
0.1	0.2	GO:0019959	interleukin-8 binding(GO:0019959)
0.1	0.3	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.1	0.3	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	0.3	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	0.9	GO:0008143	poly(A) binding(GO:0008143)
0.1	0.3	GO:0018685	alkane 1-monooxygenase activity(GO:0018685)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.5	GO:0009881	photoreceptor activity(GO:0009881)
0.0	0.2	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0071209	U7 snRNA binding(GO:0071209)
0.0	0.1	GO:0004104	cholinesterase activity(GO:0004104)
0.0	0.2	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.2	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.3	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.3	GO:0102336	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.4	GO:0031994	insulin-like growth factor I binding(GO:0031994)
0.0	0.1	GO:0004724	magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0	0.1	GO:0016823	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.2	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.5	GO:0001594	trace-amine receptor activity(GO:0001594)
0.0	0.1	GO:0015142	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.1	GO:0060228	phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0	0.5	GO:0005186	pheromone activity(GO:0005186)
0.0	0.1	GO:0000099	sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0	0.1	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0032564	dATP binding(GO:0032564)
0.0	0.1	GO:0009041	uridylate kinase activity(GO:0009041)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.0	GO:0043849	Ras palmitoyltransferase activity(GO:0043849)
0.0	0.1	GO:0004826	phenylalanine-tRNA ligase activity(GO:0004826)
0.0	0.8	GO:0001103	RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.3	GO:0017166	vinculin binding(GO:0017166)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.3	GO:0031005	filamin binding(GO:0031005)
0.0	0.3	GO:0005092	GDP-dissociation inhibitor activity(GO:0005092)
0.0	0.1	GO:0045340	mercury ion binding(GO:0045340)
0.0	0.0	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0052723	inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.0	0.7	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624)
0.0	0.1	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.2	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.1	GO:0004594	pantothenate kinase activity(GO:0004594)
0.0	0.3	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0042895	antibiotic transporter activity(GO:0042895)
0.0	0.7	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0019763	immunoglobulin receptor activity(GO:0019763)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.2	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	0.0	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.2	GO:0005542	folic acid binding(GO:0005542)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0004322	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.0	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0004174	electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.1	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0004083	bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0	0.0	GO:0004346	glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0	0.0	GO:0008073	ornithine decarboxylase inhibitor activity(GO:0008073)
0.0	0.0	GO:0035650	AP-1 adaptor complex binding(GO:0035650)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.0	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.1	GO:0019869	chloride channel inhibitor activity(GO:0019869)
0.0	0.0	GO:0004772	sterol O-acyltransferase activity(GO:0004772)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.0	GO:0031708	endothelin B receptor binding(GO:0031708)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0034416	bisphosphoglycerate phosphatase activity(GO:0034416)
0.0	0.1	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0016886	ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.2	GO:0016594	glycine binding(GO:0016594)
0.0	0.0	GO:0043398	HLH domain binding(GO:0043398)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0016803	ether hydrolase activity(GO:0016803)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0001135	transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0	0.0	GO:0001134	transcription factor activity, transcription factor recruiting(GO:0001134)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0030984	kininogen binding(GO:0030984)
0.0	0.4	GO:0030507	spectrin binding(GO:0030507)
0.0	0.1	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.1	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.0	0.3	GO:0046961	proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	0.1	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.3	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.0	GO:0016801	hydrolase activity, acting on ether bonds(GO:0016801)
0.0	0.1	GO:0003720	telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0	0.1	GO:0004767	sphingomyelin phosphodiesterase activity(GO:0004767)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.2	GO:0008758	thiamine-pyrophosphatase activity(GO:0004787) UDP-2,3-diacylglucosamine hydrolase activity(GO:0008758) dATP pyrophosphohydrolase activity(GO:0008828) dihydroneopterin monophosphate phosphatase activity(GO:0019176) dihydroneopterin triphosphate pyrophosphohydrolase activity(GO:0019177) dTTP diphosphatase activity(GO:0036218) phosphocholine hydrolase activity(GO:0044606)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.0	GO:0033265	choline binding(GO:0033265)
0.0	0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.0	GO:0003985	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.2	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.0	GO:0005119	smoothened binding(GO:0005119)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.0	GO:0008502	melatonin receptor activity(GO:0008502)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0	0.1	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.1	GO:0015386	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.0	GO:0005105	type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0	0.0	GO:0003840	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.0	GO:0003829	beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.0	0.0	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.0	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.0	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.0	GO:0004065	arylsulfatase activity(GO:0004065)
0.0	0.0	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.0	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.5	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.4	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	PID REELIN PATHWAY	Reelin signaling pathway
0.2	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.2	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.5	PID HNF3A PATHWAY	FOXA1 transcription factor network
0.2	PID INTEGRIN4 PATHWAY	Alpha6 beta4 integrin-ligand interactions
0.4	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	ST G ALPHA I PATHWAY	G alpha i Pathway
0.0	ST GRANULE CELL SURVIVAL PATHWAY	Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0	SA TRKA RECEPTOR	The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.1	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.0	PID ALK2 PATHWAY	ALK2 signaling events
0.7	PID TRKR PATHWAY	Neurotrophic factor-mediated Trk receptor signaling
0.4	PID IL6 7 PATHWAY	IL6-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.6	REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS	Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.7	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.2	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.1	REACTOME ACYL CHAIN REMODELLING OF PG	Genes involved in Acyl chain remodelling of PG
0.1	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1	REACTOME LIPOPROTEIN METABOLISM	Genes involved in Lipoprotein metabolism
0.5	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.5	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.3	REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS	Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.4	REACTOME ACYL CHAIN REMODELLING OF PE	Genes involved in Acyl chain remodelling of PE
0.0	REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN	Genes involved in Platelet Adhesion to exposed collagen
0.1	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.2	REACTOME UNWINDING OF DNA	Genes involved in Unwinding of DNA
0.1	REACTOME OPSINS	Genes involved in Opsins
0.2	REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX	Genes involved in TRAF6 mediated induction of TAK1 complex
0.1	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.3	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.2	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.3	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.2	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.0	REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Glutamate Neurotransmitter Release Cycle
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.4	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response

Results for Sox6_Sox9

Z-value: 1.72

Motif logo

Transcription factors associated with Sox6_Sox9

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox6_Sox9 motif across conditions

Conditions sorted by the z-value of the Sox6_Sox9 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox6_Sox9

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: