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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Sox7

Z-value: 1.43

Motif logo

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Transcription factors associated with Sox7

Gene Symbol Gene ID Gene Info
Sox7
ENSMUSG00000063060.5 SRY (sex determining region Y)-box 7

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_63942319_63942611Sox712080.4560010.853.2e-02Click!
chr14_63957868_63958033Sox7142770.157822-0.815.3e-02Click!
chr14_63941003_63941175Sox725840.258372-0.786.7e-02Click!
chr14_63943165_63943771Sox72050.936046-0.749.0e-02Click!
chr14_63941556_63941788Sox720010.3059360.711.1e-01Click!

Activity of the Sox7 motif across conditions

Conditions sorted by the z-value of the Sox7 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr1_127899545_127899941 1.63 Rab3gap1
 RAB3 GTPase activating protein subunit 1
 1170
 0.47
chr7_114735164_114735333 1.15 Insc
 INSC spindle orientation adaptor protein
 8446
 0.16
chr4_22498530_22498747 1.03 Gm30731
 predicted gene, 30731
 8090
 0.16
chr9_45204142_45204293 0.92 Tmprss4
 transmembrane protease, serine 4
 125
 0.93
chr4_44920931_44921086 0.91 Zcchc7
 zinc finger, CCHC domain containing 7
 2110
 0.25
chr1_67211421_67211668 0.90 Gm15668
 predicted gene 15668
 37656
 0.16
chr5_32243149_32243309 0.85 Plb1
 phospholipase B1
 4122
 0.22
chr14_21102558_21102733 0.83 Adk
 adenosine kinase
 26493
 0.19
chr10_87884302_87884648 0.82 Igf1os
 insulin-like growth factor 1, opposite strand
 21094
 0.18
chr2_70813245_70813396 0.81 Tlk1
 tousled-like kinase 1
 11908
 0.21
chr8_104789386_104789560 0.79 Gm45782
 predicted gene 45782
 3645
 0.12
chr1_130734318_130734676 0.77 AA986860
 expressed sequence AA986860
 2387
 0.14
chr1_67160278_67160544 0.75 Cps1
 carbamoyl-phosphate synthetase 1
 37385
 0.17
chr8_93183400_93183567 0.72 Gm45909
 predicted gene 45909
 7875
 0.13
chr7_113961934_113962117 0.70 Gm45615
 predicted gene 45615
 124873
 0.05
chr2_134947281_134947437 0.69 Gm14036
 predicted gene 14036
 143410
 0.04
chr4_63360320_63360510 0.68 Orm2
 orosomucoid 2
 2034
 0.19
chr13_96592864_96593019 0.68 Gm48139
 predicted gene, 48139
 12736
 0.12
chr4_47366562_47366857 0.67 Tgfbr1
 transforming growth factor, beta receptor I
 13099
 0.22
chr6_27782346_27782517 0.67 Gm26310
 predicted gene, 26310
 114344
 0.07
chr10_87913707_87914126 0.67 Igf1os
 insulin-like growth factor 1, opposite strand
 50535
 0.11
chr15_94674453_94674604 0.66 Gm25546
 predicted gene, 25546
 6858
 0.25
chr12_104342354_104343298 0.66 Serpina3k
 serine (or cysteine) peptidase inhibitor, clade A, member 3K
 4340
 0.13
chr2_118307958_118308132 0.65 1700054M17Rik
 RIKEN cDNA 1700054M17 gene
 3131
 0.19
chr15_3482890_3483092 0.63 Ghr
 growth hormone receptor
 11347
 0.28
chr4_107313475_107313626 0.63 Yipf1
 Yip1 domain family, member 1
 813
 0.49
chr9_66699874_66700052 0.63 Car12
 carbonic anhydrase 12
 13723
 0.2
chr18_33436230_33436484 0.63 Nrep
 neuronal regeneration related protein
 27078
 0.18
chr6_23387093_23387244 0.62 Cadps2
 Ca2+-dependent activator protein for secretion 2
 31249
 0.21
chr8_22860131_22860751 0.62 Kat6a
 K(lysine) acetyltransferase 6A
 892
 0.52
chr2_155062362_155062698 0.61 Gm45609
 predicted gene 45609
 11651
 0.13
chr8_25750286_25750467 0.60 Ddhd2
 DDHD domain containing 2
 526
 0.61
chr8_42311444_42311600 0.60 Gm6180
 predicted pseudogene 6180
 64611
 0.15
chr15_54578033_54578470 0.59 Mal2
 mal, T cell differentiation protein 2
 7059
 0.27
chr9_45958350_45958531 0.59 Sidt2
 SID1 transmembrane family, member 2
 3182
 0.13
chr6_13676526_13676747 0.59 Bmt2
 base methyltransferase of 25S rRNA 2
 1302
 0.55
chr19_39346810_39347020 0.59 Cyp2c72-ps
 cytochrome P450, family 2, subfamily c, polypeptide 72, pseudogene
 452
 0.87
chr11_106468981_106469217 0.59 Ern1
 endoplasmic reticulum (ER) to nucleus signalling 1
 18697
 0.14
chr8_26350253_26350419 0.58 Gm31784
 predicted gene, 31784
 38002
 0.12
chr16_43535731_43535882 0.57 Zbtb20
 zinc finger and BTB domain containing 20
 25498
 0.2
chr5_20858526_20858689 0.57 Phtf2
 putative homeodomain transcription factor 2
 3416
 0.23
chr3_105737986_105738138 0.56 Gm43328
 predicted gene 43328
 4185
 0.13
chr3_62340540_62340713 0.56 9330121J05Rik
 RIKEN cDNA 9330121J05 gene
 94
 0.7
chr11_29130922_29131328 0.56 Pnpt1
 polyribonucleotide nucleotidyltransferase 1
 377
 0.88
chr17_84742495_84742888 0.56 Lrpprc
 leucine-rich PPR-motif containing
 8571
 0.17
chr6_52009095_52009246 0.55 Skap2
 src family associated phosphoprotein 2
 3345
 0.2
chr11_16867245_16867846 0.55 Egfr
 epidermal growth factor receptor
 10605
 0.2
chr4_117131790_117132241 0.55 Plk3
 polo like kinase 3
 1784
 0.13
chr5_130015627_130015778 0.55 Asl
 argininosuccinate lyase
 980
 0.41
chr13_91748092_91748287 0.54 Gm27656
 predicted gene, 27656
 3917
 0.17
chr5_91039831_91039982 0.54 Epgn
 epithelial mitogen
 12442
 0.17
chr6_117360291_117360442 0.53 Gm4640
 predicted gene 4640
 63251
 0.12
chr8_127515465_127515616 0.53 Gm6921
 predicted pseudogene 6921
 45895
 0.17
chr7_63899068_63899509 0.51 Gm27252
 predicted gene 27252
 1314
 0.37
chr4_40145230_40145427 0.51 Aco1
 aconitase 1
 2247
 0.3
chr6_149150480_149150842 0.51 Etfbkmt
 electron transfer flavoprotein beta subunit lysine methyltransferase
 9015
 0.13
chr15_82433343_82433494 0.50 Cyp2d9
 cytochrome P450, family 2, subfamily d, polypeptide 9
 19
 0.57
chr9_119309703_119309944 0.50 Gm22729
 predicted gene, 22729
 3066
 0.17
chr2_146311135_146311471 0.50 Gm14117
 predicted gene 14117
 5756
 0.24
chr1_63122681_63122832 0.49 Gm20342
 predicted gene, 20342
 5638
 0.1
chr8_95751194_95751345 0.49 Mir7073
 microRNA 7073
 1945
 0.17
chr3_82036127_82036278 0.49 Gucy1b1
 guanylate cyclase 1, soluble, beta 1
 880
 0.6
chr1_119648022_119648226 0.48 Epb41l5
 erythrocyte membrane protein band 4.1 like 5
 493
 0.78
chr4_102583510_102583771 0.48 Pde4b
 phosphodiesterase 4B, cAMP specific
 3918
 0.35
chr4_71811423_71811574 0.48 Gm11232
 predicted gene 11232
 53533
 0.15
chr2_122158672_122158840 0.48 Trim69
 tripartite motif-containing 69
 1944
 0.21
chr4_12481585_12481744 0.48 Gm37985
 predicted gene, 37985
 115724
 0.06
chr4_9665988_9666139 0.48 Asph
 aspartate-beta-hydroxylase
 3023
 0.24
chr9_32870948_32871133 0.47 Gm37167
 predicted gene, 37167
 31118
 0.16
chr9_62357318_62357469 0.47 Anp32a
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 9545
 0.21
chr2_31511401_31511572 0.47 Ass1
 argininosuccinate synthetase 1
 7004
 0.18
chr16_35491110_35491284 0.47 Pdia5
 protein disulfide isomerase associated 5
 324
 0.87
chr4_15066667_15066833 0.47 Gm11844
 predicted gene 11844
 44168
 0.16
chr16_42998828_42999221 0.46 Ndufs5-ps
 NADH:ubiquinone oxidoreductase core subunit S5, pseudogene
 43393
 0.16
chr5_122494527_122494678 0.46 Gm43360
 predicted gene 43360
 306
 0.77
chr6_31551331_31551519 0.46 Podxl
 podocalyxin-like
 12556
 0.18
chr14_59205202_59205353 0.46 Rcbtb1
 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
 336
 0.88
chr13_81212164_81212315 0.46 Gm48566
 predicted gene, 48566
 28545
 0.2
chr7_110816193_110816374 0.45 Rnf141
 ring finger protein 141
 5000
 0.16
chr15_5106677_5106828 0.45 Card6
 caspase recruitment domain family, member 6
 1732
 0.22
chr4_108095142_108095451 0.44 Podn
 podocan
 1149
 0.41
chr16_76371516_76371667 0.44 Nrip1
 nuclear receptor interacting protein 1
 1446
 0.43
chr2_34775525_34776380 0.43 Hspa5
 heat shock protein 5
 1105
 0.4
chr1_100410526_100410677 0.43 Gm29667
 predicted gene 29667
 127810
 0.05
chr17_30042343_30042527 0.42 Zfand3
 zinc finger, AN1-type domain 3
 17947
 0.15
chr4_41331357_41331705 0.41 Gm26084
 predicted gene, 26084
 14420
 0.1
chr1_65170171_65170540 0.41 Idh1
 isocitrate dehydrogenase 1 (NADP+), soluble
 5209
 0.15
chr5_122494845_122494996 0.41 Gm43360
 predicted gene 43360
 12
 0.94
chr10_63038751_63038902 0.39 Pbld2
 phenazine biosynthesis-like protein domain containing 2
 14314
 0.09
chr16_46853625_46853776 0.39 Gm6912
 predicted gene 6912
 220498
 0.02
chr2_11427432_11427583 0.39 Gm13296
 predicted gene 13296
 7283
 0.12
chr3_133740354_133740509 0.39 Gm6135
 prediticted gene 6135
 51073
 0.13
chr11_32681512_32681693 0.39 Fbxw11
 F-box and WD-40 domain protein 11
 38698
 0.16
chr11_106429328_106429479 0.39 Icam2
 intercellular adhesion molecule 2
 41328
 0.1
chr6_115653735_115653886 0.39 Gm14335
 predicted gene 14335
 14751
 0.11
chr6_67268636_67268787 0.38 Serbp1
 serpine1 mRNA binding protein 1
 1381
 0.34
chr4_48272957_48273115 0.38 Erp44
 endoplasmic reticulum protein 44
 6416
 0.2
chr19_43808546_43808716 0.38 Abcc2
 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
 1891
 0.28
chr3_52006994_52007318 0.37 Gm37465
 predicted gene, 37465
 3131
 0.17
chr18_20554666_20554835 0.37 Dsg2
 desmoglein 2
 3324
 0.21
chr1_164435834_164435997 0.37 Atp1b1
 ATPase, Na+/K+ transporting, beta 1 polypeptide
 7804
 0.15
chr1_127787315_127787490 0.37 Ccnt2
 cyclin T2
 9169
 0.16
chr3_24123037_24123188 0.37 Naaladl2
 N-acetylated alpha-linked acidic dipeptidase-like 2
 150927
 0.05
chr3_36480639_36480833 0.37 1810062G17Rik
 RIKEN cDNA 1810062G17 gene
 4799
 0.13
chr8_105090981_105091315 0.36 Ces3b
 carboxylesterase 3B
 2529
 0.16
chr3_135442828_135442979 0.36 Ube2d3
 ubiquitin-conjugating enzyme E2D 3
 3692
 0.12
chr9_76727753_76728144 0.36 Gm22938
 predicted gene, 22938
 11201
 0.17
chr3_84234361_84234584 0.36 Trim2
 tripartite motif-containing 2
 13583
 0.23
chr6_17478662_17478867 0.35 Met
 met proto-oncogene
 12477
 0.21
chr2_148031539_148031764 0.35 9030622O22Rik
 RIKEN cDNA 9030622O22 gene
 6619
 0.18
chr9_92257106_92257271 0.35 Plscr1
 phospholipid scramblase 1
 6846
 0.15
chr13_9495114_9495298 0.35 Gm48871
 predicted gene, 48871
 49306
 0.11
chr13_4061646_4061992 0.35 Akr1c14
 aldo-keto reductase family 1, member C14
 2228
 0.22
chr1_51856674_51857057 0.35 Myo1b
 myosin IB
 5759
 0.17
chr6_29852245_29852396 0.35 Ahcyl2
 S-adenosylhomocysteine hydrolase-like 2
 1440
 0.41
chr17_78379527_78379767 0.35 Fez2
 fasciculation and elongation protein zeta 2 (zygin II)
 21783
 0.15
chr1_67127092_67127716 0.34 Cps1
 carbamoyl-phosphate synthetase 1
 4378
 0.28
chr5_146293255_146293729 0.34 Cdk8
 cyclin-dependent kinase 8
 1418
 0.38
chr10_5408928_5409079 0.34 Syne1
 spectrin repeat containing, nuclear envelope 1
 40517
 0.18
chr12_8694008_8694159 0.34 Pum2
 pumilio RNA-binding family member 2
 4013
 0.27
chr11_115219587_115219763 0.34 Nat9
 N-acetyltransferase 9 (GCN5-related, putative)
 31816
 0.08
chr16_84837970_84838147 0.34 Atp5j
 ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
 2433
 0.2
chr8_125493583_125493749 0.34 Sipa1l2
 signal-induced proliferation-associated 1 like 2
 956
 0.69
chr11_60248805_60248956 0.34 Tom1l2
 target of myb1-like 2 (chicken)
 3211
 0.16
chr19_40141682_40141833 0.33 Cyp2c70
 cytochrome P450, family 2, subfamily c, polypeptide 70
 45529
 0.11
chr7_115680029_115680180 0.33 Sox6
 SRY (sex determining region Y)-box 6
 17739
 0.29
chr3_130339266_130339443 0.33 Gm22682
 predicted gene, 22682
 133889
 0.04
chr14_11158870_11159044 0.33 Slc25a5-ps
 Slc25a5 retrotransposed pseudogene
 2572
 0.28
chr13_4028561_4028716 0.33 Gm47853
 predicted gene, 47853
 5469
 0.14
chr12_79435773_79435986 0.32 Rad51b
 RAD51 paralog B
 108526
 0.06
chr4_134917124_134917439 0.32 Tmem50a
 transmembrane protein 50A
 2257
 0.24
chr12_80124026_80124199 0.32 2310015A10Rik
 RIKEN cDNA 2310015A10 gene
 2973
 0.17
chr15_3453354_3453796 0.32 Ghr
 growth hormone receptor
 18069
 0.26
chr10_17946556_17946707 0.32 Heca
 hdc homolog, cell cycle regulator
 1436
 0.47
chr16_11176623_11176798 0.32 Zc3h7a
 zinc finger CCCH type containing 7 A
 317
 0.74
chr15_97025258_97025453 0.32 Slc38a4
 solute carrier family 38, member 4
 5033
 0.31
chr6_35338820_35339318 0.32 1700065J11Rik
 RIKEN cDNA 1700065J11 gene
 8223
 0.18
chr2_43592187_43592360 0.32 Kynu
 kynureninase
 7342
 0.3
chr9_46481072_46481223 0.31 Gm47144
 predicted gene, 47144
 23926
 0.16
chr1_71595444_71595633 0.31 Fn1
 fibronectin 1
 4467
 0.23
chr11_18900021_18900190 0.31 2900018N21Rik
 RIKEN cDNA 2900018N21 gene
 10265
 0.16
chr4_19970512_19970663 0.31 4930480G23Rik
 RIKEN cDNA 4930480G23 gene
 27649
 0.17
chr5_136258958_136259125 0.31 Sh2b2
 SH2B adaptor protein 2
 12485
 0.13
chr5_17998832_17999006 0.31 Gnat3
 guanine nucleotide binding protein, alpha transducing 3
 36370
 0.22
chr19_44394517_44394772 0.31 Scd1
 stearoyl-Coenzyme A desaturase 1
 12046
 0.14
chr4_108849580_108849741 0.31 Kti12
 KTI12 homolog, chromatin associated
 1875
 0.25
chr7_66075917_66076093 0.30 Gm45081
 predicted gene 45081
 3468
 0.14
chr19_59979470_59979621 0.30 Gm4219
 predicted gene 4219
 35823
 0.15
chr5_23578433_23578591 0.30 Srpk2
 serine/arginine-rich protein specific kinase 2
 29142
 0.15
chr10_69218422_69218684 0.30 Rhobtb1
 Rho-related BTB domain containing 1
 832
 0.61
chr3_95324375_95324754 0.30 Cers2
 ceramide synthase 2
 3624
 0.1
chr8_47712885_47713036 0.30 E030037K01Rik
 RIKEN cDNA E030037K01 gene
 306
 0.75
chr13_96668366_96668901 0.30 Hmgcr
 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
 1021
 0.47
chr7_127277970_127278299 0.30 Sephs2
 selenophosphate synthetase 2
 4079
 0.08
chr6_93770467_93770664 0.30 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 21974
 0.21
chr2_59169467_59169618 0.30 Pkp4
 plakophilin 4
 7615
 0.2
chr3_60582048_60582207 0.29 Mbnl1
 muscleblind like splicing factor 1
 13514
 0.2
chr13_119378503_119378661 0.29 Nnt
 nicotinamide nucleotide transhydrogenase
 30370
 0.15
chr2_31515291_31515653 0.28 Ass1
 argininosuccinate synthetase 1
 3018
 0.23
chr9_74790782_74790933 0.28 Gm22315
 predicted gene, 22315
 8787
 0.19
chr1_57386674_57386899 0.28 Tyw5
 tRNA-yW synthesizing protein 5
 3985
 0.16
chr4_92376164_92376339 0.28 Gm12638
 predicted gene 12638
 2903
 0.4
chr10_67191188_67191347 0.28 Jmjd1c
 jumonji domain containing 1C
 5514
 0.23
chr9_65748388_65748657 0.28 Zfp609
 zinc finger protein 609
 47378
 0.11
chr11_16767286_16767565 0.28 Egfr
 epidermal growth factor receptor
 15195
 0.19
chr1_168242978_168243129 0.28 Pbx1
 pre B cell leukemia homeobox 1
 78391
 0.1
chr12_57444721_57445109 0.28 Gm16246
 predicted gene 16246
 5205
 0.25
chr3_97616365_97616788 0.28 Chd1l
 chromodomain helicase DNA binding protein 1-like
 6373
 0.15
chr11_117359987_117360146 0.28 Septin9
 septin 9
 706
 0.68
chr9_120776284_120776475 0.28 Gm47066
 predicted gene, 47066
 15607
 0.11
chr15_6891673_6891824 0.28 Osmr
 oncostatin M receptor
 16779
 0.26
chr16_22241727_22242034 0.28 Gm36796
 predicted gene, 36796
 2288
 0.19
chr7_99201987_99202161 0.28 Gm45012
 predicted gene 45012
 292
 0.86
chr17_64767271_64767462 0.27 Dreh
 down-regulated in hepatocellular carcinoma
 255
 0.93
chr1_135210155_135210339 0.27 Gm4204
 predicted gene 4204
 21748
 0.1
chr3_133833846_133834006 0.27 Gm30484
 predicted gene, 30484
 15408
 0.23
chr17_32348126_32348277 0.27 Akap8l
 A kinase (PRKA) anchor protein 8-like
 2305
 0.19
chr10_87718160_87718329 0.27 Gm48195
 predicted gene, 48195
 29666
 0.21
chr11_16862337_16862489 0.26 Egfr
 epidermal growth factor receptor
 15737
 0.19
chr7_89401915_89402333 0.26 Tmem135
 transmembrane protein 135
 2098
 0.22
chr19_57272214_57272473 0.26 4930449E18Rik
 RIKEN cDNA 4930449E18 gene
 1617
 0.39
chr18_12635155_12635343 0.26 Ttc39c
 tetratricopeptide repeat domain 39C
 8095
 0.15
chr18_64628060_64628409 0.26 Gm6978
 predicted gene 6978
 15135
 0.14
chr6_119390969_119391120 0.26 Adipor2
 adiponectin receptor 2
 796
 0.67
chr15_31230889_31231047 0.26 Dap
 death-associated protein
 5772
 0.19
chr13_52188692_52188881 0.25 Gm48199
 predicted gene, 48199
 8375
 0.27
chr7_35142488_35142656 0.25 Gm35665
 predicted gene, 35665
 1123
 0.34
chr17_13687760_13687927 0.25 Gm16046
 predicted gene 16046
 4327
 0.17
chrX_136321797_136321962 0.25 Nsa2-ps2
 NSA2 ribosome biogenesis homolog, pseudogene 2
 6420
 0.09
chr2_35103269_35103589 0.25 AI182371
 expressed sequence AI182371
 1886
 0.29
chr14_68297607_68297758 0.25 Gm47212
 predicted gene, 47212
 79429
 0.1
chr11_60837742_60838309 0.25 Dhrs7b
 dehydrogenase/reductase (SDR family) member 7B
 7346
 0.1
chr3_105758672_105758857 0.25 Rap1a
 RAS-related protein 1a
 8436
 0.11
chr1_60616128_60616279 0.25 Gm23762
 predicted gene, 23762
 2400
 0.22
chr1_166153672_166153856 0.25 Gpa33
 glycoprotein A33 (transmembrane)
 23297
 0.15
chr12_79599250_79599471 0.25 Rad51b
 RAD51 paralog B
 272007
 0.01
chr6_56795662_56795822 0.25 Kbtbd2
 kelch repeat and BTB (POZ) domain containing 2
 1005
 0.43
chr1_84300039_84300190 0.25 Pid1
 phosphotyrosine interaction domain containing 1
 15469
 0.24
chr13_4205947_4206185 0.25 Akr1c13
 aldo-keto reductase family 1, member C13
 12208
 0.13
chr11_86739271_86739543 0.25 Cltc
 clathrin, heavy polypeptide (Hc)
 12924
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.2 0.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.4 GO:0009826 unidimensional cell growth(GO:0009826)
0.1 0.7 GO:0006526 arginine biosynthetic process(GO:0006526)
0.1 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.2 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.2 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:2000152 regulation of ubiquitin-specific protease activity(GO:2000152)
0.1 0.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.1 GO:0060128 corticotropin hormone secreting cell differentiation(GO:0060128)
0.0 0.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.1 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.2 GO:0042977 activation of JAK2 kinase activity(GO:0042977)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.1 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.1 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:0045908 negative regulation of vasodilation(GO:0045908)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0 0.1 GO:1990168 protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0 0.1 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.0 0.1 GO:0015959 diadenosine polyphosphate metabolic process(GO:0015959)
0.0 0.0 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.2 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.1 GO:0048478 replication fork protection(GO:0048478)
0.0 0.1 GO:0019627 urea metabolic process(GO:0019627)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.1 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.2 GO:0055064 chloride ion homeostasis(GO:0055064)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.1 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.1 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.1 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.0 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983)
0.0 0.1 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.1 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.0 0.0 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0042701 progesterone secretion(GO:0042701)
0.0 0.2 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0033133 positive regulation of glucokinase activity(GO:0033133)
0.0 0.0 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.0 0.0 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210)
0.0 0.1 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 0.1 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.0 0.3 GO:0035162 embryonic hemopoiesis(GO:0035162)
0.0 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.0 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:0032264 IMP salvage(GO:0032264)
0.0 0.1 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
0.0 0.1 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.0 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.0 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.0 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.0 0.1 GO:0046218 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.0 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.0 0.1 GO:0042421 norepinephrine biosynthetic process(GO:0042421)
0.0 0.1 GO:0035336 long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0 0.0 GO:0035935 androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.0 GO:0006059 hexitol metabolic process(GO:0006059)
0.0 0.1 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.0 GO:2000338 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.0 GO:0006188 IMP biosynthetic process(GO:0006188) 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.0 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.0 GO:0003099 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.0 GO:0010887 negative regulation of cholesterol storage(GO:0010887)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.1 0.3 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.3 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.5 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0097648 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.1 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0098533 ATPase dependent transmembrane transport complex(GO:0098533)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)
0.0 0.1 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.3 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.2 GO:0045340 mercury ion binding(GO:0045340)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.2 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.4 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.2 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0047023 androsterone dehydrogenase activity(GO:0047023)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.1 GO:0071614 linoleic acid epoxygenase activity(GO:0071614)
0.0 0.1 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.6 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.1 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.0 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.1 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.1 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.0 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.1 GO:0036137 kynurenine-oxoglutarate transaminase activity(GO:0016212) kynurenine aminotransferase activity(GO:0036137)
0.0 0.0 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0016443 bidentate ribonuclease III activity(GO:0016443)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.0 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.0 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.0 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.0 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.2 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.0 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.0 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.4 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.0 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.1 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.2 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.0 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)