Project

ENCSR904DTN: DNase-seq of mouse liver in constant darkness

Navigation

Downloads

Results for Sox8

Z-value: 2.03

Motif logo

Transcription factors associated with Sox8

Gene Symbol	Gene ID	Gene Info
Sox8 Ensembl NCBI MGI UniProt	ENSMUSG00000024176.4	SRY (sex determining region Y)-box 8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_25567899_25568067	Sox8	2231	0.133309	0.06	9.1e-01	Click!

Activity of the Sox8 motif across conditions

Conditions sorted by the z-value of the Sox8 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_99858543_99858709	1.78	Efcab11	EF-hand calcium binding domain 11	24231	0.11
chr1_21246022_21246220	1.60	Gsta3	glutathione S-transferase, alpha 3	5492	0.12
chr1_21250942_21251436	1.45	Gsta3	glutathione S-transferase, alpha 3	2332	0.18
chr1_21263882_21264033	1.43	Gm28836	predicted gene 28836	7636	0.11
chr14_7870473_7870795	1.26	Flnb	filamin, beta	14107	0.18
chr6_24610042_24610446	1.18	Lmod2	leiomodin 2 (cardiac)	12482	0.14
chr3_18428558_18428773	1.17	Gm30667	predicted gene, 30667	32589	0.18
chr19_40179770_40179927	1.13	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	7438	0.16
chr19_17879683_17879834	1.06	Gm50181	predicted gene, 50181	5929	0.16
chr8_93176469_93176646	1.02	Ces1d	carboxylesterase 1D	1268	0.36
chr10_87556368_87556519	1.01	Pah	phenylalanine hydroxylase	9770	0.23
chr3_138293165_138293347	1.01	Gm16559	predicted gene 16559	13766	0.11
chrX_111626357_111626522	1.00	Gm7340	predicted gene 7340	54740	0.14
chr14_120338170_120338321	0.95	Mbnl2	muscleblind like splicing factor 2	31789	0.19
chr17_28420256_28420436	0.94	Fkbp5	FK506 binding protein 5	1819	0.21
chr1_67104802_67105196	0.93	Cps1	carbamoyl-phosphate synthetase 1	18027	0.21
chr19_40158328_40158479	0.89	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	28883	0.13
chr16_28927241_28927396	0.89	Mb21d2	Mab-21 domain containing 2	2355	0.37
chr6_99302525_99302751	0.86	Foxp1	forkhead box P1	36106	0.2
chr11_43900248_43900399	0.86	Adra1b	adrenergic receptor, alpha 1b	887	0.69
chr11_16815536_16815687	0.85	Egfros	epidermal growth factor receptor, opposite strand	15091	0.21
chr3_58685224_58685416	0.84	Siah2	siah E3 ubiquitin protein ligase 2	717	0.56
chr4_53101372_53101542	0.82	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	58438	0.11
chr8_18713888_18714465	0.82	Angpt2	angiopoietin 2	14629	0.17
chr10_20473895_20474094	0.82	Pde7b	phosphodiesterase 7B	27103	0.17
chr6_138081648_138081799	0.79	Slc15a5	solute carrier family 15, member 5	1807	0.47
chr11_110488163_110488353	0.79	Map2k6	mitogen-activated protein kinase kinase 6	9219	0.27
chr2_118448093_118448276	0.78	Eif2ak4	eukaryotic translation initiation factor 2 alpha kinase 4	8976	0.16
chr8_93164567_93164980	0.78	Ces1d	carboxylesterase 1D	5202	0.15
chr15_10718434_10718784	0.75	4930556M19Rik	RIKEN cDNA 4930556M19 gene	758	0.66
chr5_147747897_147748048	0.75	Gm43156	predicted gene 43156	2456	0.3
chr9_74881023_74881569	0.75	Onecut1	one cut domain, family member 1	14812	0.15
chr13_101718622_101718773	0.73	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	16593	0.2
chr4_124657279_124657648	0.73	Gm2164	predicted gene 2164	294	0.7
chr5_72948525_72948751	0.73	Slain2	SLAIN motif family, member 2	139	0.94
chr13_19395072_19395660	0.72	Gm42683	predicted gene 42683	87	0.82
chr19_44394517_44394772	0.71	Scd1	stearoyl-Coenzyme A desaturase 1	12046	0.14
chr6_149169218_149169449	0.70	Amn1	antagonist of mitotic exit network 1	4038	0.17
chr11_117083977_117084371	0.70	Gm24323	predicted gene, 24323	1662	0.21
chr13_101681950_101682101	0.69	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	10318	0.23
chr8_56344936_56345137	0.69	Gm45540	predicted gene 45540	33732	0.18
chr12_104083020_104083260	0.69	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	2491	0.16
chr6_52638634_52638785	0.69	Gm24355	predicted gene, 24355	646	0.6
chr3_121437304_121437494	0.68	Gm42929	predicted gene 42929	9353	0.14
chr3_12608407_12608567	0.68	Gm2429	predicted gene 2429	22773	0.28
chr15_10206312_10206463	0.67	Prlr	prolactin receptor	7078	0.3
chr2_72975847_72976140	0.66	Sp3	trans-acting transcription factor 3	3293	0.17
chr6_23130335_23130517	0.66	Aass	aminoadipate-semialdehyde synthase	2490	0.23
chr10_127408250_127408460	0.66	Gm23819	predicted gene, 23819	3963	0.13
chr4_6916841_6916992	0.65	Tox	thymocyte selection-associated high mobility group box	73567	0.12
chr4_76362117_76362298	0.64	Ptprd	protein tyrosine phosphatase, receptor type, D	17964	0.23
chr14_7871226_7871377	0.63	Flnb	filamin, beta	13440	0.19
chr2_11502907_11503112	0.63	Pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3	908	0.5
chr1_130733366_130733529	0.63	AA986860	expressed sequence AA986860	1337	0.24
chr8_26593661_26593813	0.62	Gm39149	predicted gene, 39149	13935	0.17
chr1_67175551_67175991	0.61	Cps1	carbamoyl-phosphate synthetase 1	52745	0.13
chr8_68057735_68057886	0.60	Psd3	pleckstrin and Sec7 domain containing 3	4417	0.29
chr17_81378554_81378979	0.60	Gm50044	predicted gene, 50044	7933	0.26
chrY_90800164_90800315	0.59	Gm47283	predicted gene, 47283	9788	0.18
chr12_104343910_104344587	0.59	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	5762	0.12
chr18_39139135_39139286	0.58	Arhgap26	Rho GTPase activating protein 26	39899	0.19
chr15_94674453_94674604	0.58	Gm25546	predicted gene, 25546	6858	0.25
chrX_42087864_42088015	0.57	Xiap	X-linked inhibitor of apoptosis	5789	0.22
chr16_31948717_31948903	0.57	Ncbp2	nuclear cap binding protein subunit 2	164	0.65
chr7_34265793_34265944	0.57	4931406P16Rik	RIKEN cDNA 4931406P16 gene	8649	0.1
chr5_53985972_53986134	0.56	Stim2	stromal interaction molecule 2	12446	0.23
chr6_104668567_104668720	0.56	Cntn6	contactin 6	175395	0.04
chr14_66279629_66279835	0.56	Ptk2b	PTK2 protein tyrosine kinase 2 beta	1250	0.42
chr9_63328875_63329026	0.56	Map2k5	mitogen-activated protein kinase kinase 5	25807	0.18
chr18_35552195_35552361	0.55	Snhg4	small nucleolar RNA host gene 4	1093	0.25
chr19_40181161_40181312	0.55	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	6050	0.17
chr5_107874706_107874894	0.55	Evi5	ecotropic viral integration site 5	244	0.86
chr13_45863946_45864126	0.55	Atxn1	ataxin 1	8252	0.26
chr10_68773346_68773497	0.55	Tmem26	transmembrane protein 26	49597	0.16
chr6_51681013_51681175	0.55	Gm38811	predicted gene, 38811	29987	0.19
chr10_80577672_80578424	0.54	Klf16	Kruppel-like factor 16	727	0.41
chr15_3458621_3458946	0.54	Ghr	growth hormone receptor	12861	0.28
chr6_72117206_72117587	0.54	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	2164	0.2
chr10_93075462_93075643	0.54	Cfap54	cilia and flagella associated protein 54	5301	0.22
chr19_40165502_40165757	0.54	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	21657	0.14
chr10_111336390_111336820	0.54	Gm40761	predicted gene, 40761	519	0.8
chr18_16664042_16664193	0.54	Cdh2	cadherin 2	5952	0.3
chr1_120061736_120061887	0.54	Tmem37	transmembrane protein 37	12263	0.17
chr1_88049643_88049948	0.54	Ugt1a10	UDP glycosyltransferase 1 family, polypeptide A10	5593	0.08
chr6_6237182_6237336	0.53	Gm20619	predicted gene 20619	11400	0.21
chr1_67223699_67224148	0.53	Gm15668	predicted gene 15668	25277	0.19
chr1_67165771_67165961	0.53	Cps1	carbamoyl-phosphate synthetase 1	42840	0.16
chr16_30375250_30375569	0.53	Atp13a3	ATPase type 13A3	13076	0.2
chr15_59022742_59023374	0.53	Mtss1	MTSS I-BAR domain containing 1	17538	0.18
chr5_147053799_147054018	0.53	Lnx2	ligand of numb-protein X 2	22678	0.14
chr10_86690190_86690443	0.53	Gm15344	predicted gene 15344	2779	0.1
chr1_91421020_91421230	0.52	Hes6	hairy and enhancer of split 6	7087	0.11
chr1_61620772_61620939	0.52	4930587A21Rik	RIKEN cDNA 4930587A21 gene	294	0.88
chr3_51227403_51227633	0.52	Noct	nocturnin	3048	0.19
chr8_17783842_17784014	0.52	Csmd1	CUB and Sushi multiple domains 1	248342	0.02
chr11_16528502_16528653	0.52	Akt2-ps	thymoma viral proto-oncogene 2, pseudogene	14044	0.2
chr5_147225144_147225307	0.51	Gm24556	predicted gene, 24556	24972	0.11
chr12_71876146_71876310	0.51	Daam1	dishevelled associated activator of morphogenesis 1	13502	0.21
chr16_65665507_65665824	0.51	Gm49633	predicted gene, 49633	52246	0.14
chr6_108290766_108291042	0.51	Itpr1	inositol 1,4,5-trisphosphate receptor 1	37946	0.19
chr10_20723259_20723681	0.50	Pde7b	phosphodiesterase 7B	1226	0.53
chr17_34859202_34859695	0.50	Cfb	complement factor B	138	0.83
chr8_3049184_3049482	0.50	Gm44634	predicted gene 44634	6961	0.2
chr4_6264246_6265210	0.50	Gm11798	predicted gene 11798	3763	0.24
chr3_18180658_18180809	0.50	Gm23686	predicted gene, 23686	3108	0.31
chr6_149143880_149144031	0.49	Etfbkmt	electron transfer flavoprotein beta subunit lysine methyltransferase	2309	0.21
chr10_40023325_40023504	0.49	Mfsd4b1	major facilitator superfamily domain containing 4B1	1745	0.24
chr1_82144503_82144654	0.49	Mir6344	microRNA 6344	12662	0.22
chr4_133632580_133633016	0.48	Zdhhc18	zinc finger, DHHC domain containing 18	671	0.56
chr17_86293077_86293270	0.48	2010106C02Rik	RIKEN cDNA 2010106C02 gene	5995	0.3
chr11_84169257_84169497	0.48	Gm11437	predicted gene 11437	1901	0.28
chr8_114107838_114108061	0.48	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	25608	0.25
chr9_107759714_107759865	0.48	Rbm5	RNA binding motif protein 5	774	0.47
chr3_96442671_96442858	0.48	Gm26232	predicted gene, 26232	7682	0.06
chr5_125525672_125525920	0.48	Tmem132b	transmembrane protein 132B	5978	0.17
chr18_33433732_33433917	0.47	Nrep	neuronal regeneration related protein	29611	0.17
chr10_77636527_77636709	0.47	Ube2g2	ubiquitin-conjugating enzyme E2G 2	4568	0.09
chr1_162860588_162860757	0.47	Fmo1	flavin containing monooxygenase 1	703	0.67
chr5_87589802_87589979	0.47	Sult1e1	sulfotransferase family 1E, member 1	1704	0.22
chr6_27967716_27967883	0.47	Mir592	microRNA 592	31049	0.23
chr18_50133596_50133856	0.47	Cd63-ps	CD63 antigen, pseudogene	1000	0.53
chr2_167342069_167342220	0.47	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	7039	0.2
chr10_68129143_68129294	0.46	Arid5b	AT rich interactive domain 5B (MRF1-like)	7408	0.26
chr11_5530555_5530722	0.46	Xbp1	X-box binding protein 1	8715	0.13
chr14_115039993_115040462	0.46	Mir17hg	Mir17 host gene (non-protein coding)	2652	0.13
chr6_21804265_21804540	0.46	Tspan12	tetraspanin 12	47426	0.13
chr1_63122681_63122832	0.46	Gm20342	predicted gene, 20342	5638	0.1
chr4_6273243_6273469	0.46	Cyp7a1	cytochrome P450, family 7, subfamily a, polypeptide 1	2275	0.3
chr6_88641424_88641714	0.46	Kbtbd12	kelch repeat and BTB (POZ) domain containing 12	3619	0.23
chr10_87937503_87937727	0.46	Tyms-ps	thymidylate synthase, pseudogene	29232	0.15
chr6_29571610_29572022	0.46	Tnpo3	transportin 3	297	0.87
chr1_51877379_51877530	0.46	Gm28323	predicted gene 28323	2154	0.26
chr1_91463744_91463928	0.46	Per2	period circadian clock 2	4512	0.13
chr15_85757340_85757499	0.45	Ppara	peroxisome proliferator activated receptor alpha	14795	0.14
chr3_144110073_144110233	0.45	Gm34078	predicted gene, 34078	25601	0.2
chr2_163300587_163300782	0.45	Tox2	TOX high mobility group box family member 2	19694	0.19
chr14_21524078_21524263	0.45	Kat6b	K(lysine) acetyltransferase 6B	7295	0.24
chr9_42769307_42769458	0.45	Grik4	glutamate receptor, ionotropic, kainate 4	39317	0.19
chr5_72222804_72222958	0.45	Atp10d	ATPase, class V, type 10D	19528	0.18
chr8_105092502_105092688	0.44	Ces3b	carboxylesterase 3B	3976	0.12
chr13_37601794_37602225	0.44	Gm47753	predicted gene, 47753	19738	0.1
chr11_11894780_11894931	0.44	Ddc	dopa decarboxylase	3189	0.22
chr19_8400709_8400872	0.44	Slc22a30	solute carrier family 22, member 30	4270	0.24
chr4_76941353_76941637	0.44	Gm11246	predicted gene 11246	14184	0.22
chr11_75759248_75759399	0.44	Ywhae	tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide	7719	0.16
chr3_60097490_60097658	0.44	Sucnr1	succinate receptor 1	15672	0.18
chr11_16895293_16895616	0.44	Egfr	epidermal growth factor receptor	9731	0.2
chr14_49101182_49101371	0.44	Rpl19-ps3	ribosomal protein L19, pseudogene 3	11522	0.15
chr4_106777883_106778393	0.44	Gm12745	predicted gene 12745	3322	0.19
chr3_5425056_5425268	0.44	4930555M17Rik	RIKEN cDNA 4930555M17 gene	90171	0.09
chr1_13437959_13438111	0.44	Gm7593	predicted gene 7593	30380	0.15
chr5_103291040_103291224	0.44	4930429D17Rik	RIKEN cDNA 4930429D17 gene	7897	0.18
chr4_102583510_102583771	0.43	Pde4b	phosphodiesterase 4B, cAMP specific	3918	0.35
chr3_51253047_51253213	0.43	Elf2	E74-like factor 2	7111	0.13
chr6_94683582_94684101	0.43	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	3211	0.3
chr19_40183641_40183792	0.43	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	3570	0.19
chr17_28419864_28420015	0.43	Fkbp5	FK506 binding protein 5	1412	0.27
chr11_65787387_65787891	0.43	Map2k4	mitogen-activated protein kinase kinase 4	646	0.74
chr10_87691125_87691276	0.42	Gm48195	predicted gene, 48195	2622	0.37
chr1_162857733_162858080	0.42	Fmo1	flavin containing monooxygenase 1	1808	0.33
chr9_80672054_80672205	0.42	Gm39380	predicted gene, 39380	37866	0.19
chr10_128956612_128956935	0.42	Itga7	integrin alpha 7	3000	0.11
chr16_22438733_22438905	0.42	Etv5	ets variant 5	751	0.66
chr7_110124848_110124999	0.42	Wee1	WEE 1 homolog 1 (S. pombe)	2877	0.18
chr7_123420448_123420654	0.42	Lcmt1	leucine carboxyl methyltransferase 1	2408	0.29
chr2_134843502_134843690	0.42	Gm14036	predicted gene 14036	39647	0.17
chr1_167247272_167247459	0.42	Uck2	uridine-cytidine kinase 2	4207	0.15
chr11_87702293_87702667	0.42	1110028F11Rik	RIKEN cDNA 1110028F11 gene	357	0.76
chr15_3504126_3504331	0.41	Ghr	growth hormone receptor	32584	0.22
chr14_17684992_17685208	0.41	Thrb	thyroid hormone receptor beta	24204	0.25
chr16_43169836_43170008	0.41	Gm15712	predicted gene 15712	14651	0.21
chr15_82781420_82781584	0.41	Cyp2d41-ps	cytochrome P450, family 2, subfamily d, member 41, pseudogene	608	0.38
chr1_24699218_24699369	0.41	Lmbrd1	LMBR1 domain containing 1	20367	0.16
chr1_67160278_67160544	0.41	Cps1	carbamoyl-phosphate synthetase 1	37385	0.17
chr13_104044029_104044180	0.41	Nln	neurolysin (metallopeptidase M3 family)	6462	0.22
chr2_167950997_167951148	0.41	Ptpn1	protein tyrosine phosphatase, non-receptor type 1	24	0.98
chr17_24471759_24471919	0.41	Pgp	phosphoglycolate phosphatase	1404	0.15
chr12_8694008_8694159	0.41	Pum2	pumilio RNA-binding family member 2	4013	0.27
chr1_88200499_88200650	0.41	Ugt1a2	UDP glucuronosyltransferase 1 family, polypeptide A2	27	0.93
chr5_105353811_105354032	0.40	Gbp11	guanylate binding protein 11	7449	0.18
chr1_139848329_139848692	0.40	Cfhr2	complement factor H-related 2	10180	0.2
chr8_41099843_41100029	0.40	Mtus1	mitochondrial tumor suppressor 1	14731	0.19
chr4_48272957_48273115	0.40	Erp44	endoplasmic reticulum protein 44	6416	0.2
chr4_102806758_102806909	0.40	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	46308	0.16
chr10_96743185_96743501	0.40	Gm6859	predicted gene 6859	26485	0.15
chr7_25464843_25464994	0.40	Ceacam1	carcinoembryonic antigen-related cell adhesion molecule 1	11786	0.11
chr9_74872935_74873093	0.40	Onecut1	one cut domain, family member 1	6530	0.16
chr3_138284545_138284746	0.40	Adh1	alcohol dehydrogenase 1 (class I)	6994	0.12
chr3_101572198_101572792	0.39	Atp1a1	ATPase, Na+/K+ transporting, alpha 1 polypeptide	5065	0.19
chr5_28048047_28048198	0.39	Gm26608	predicted gene, 26608	7337	0.16
chr5_125514524_125514682	0.39	Aacs	acetoacetyl-CoA synthetase	406	0.81
chr15_52207430_52207595	0.39	Gm7543	predicted gene 7543	51611	0.14
chr16_35471313_35471717	0.39	Pdia5	protein disulfide isomerase associated 5	19074	0.14
chr2_113545947_113546266	0.39	Gm13964	predicted gene 13964	42072	0.15
chr2_27728804_27729670	0.39	Rxra	retinoid X receptor alpha	4018	0.31
chr6_112495267_112495418	0.39	Oxtr	oxytocin receptor	5399	0.18
chr6_37510726_37510877	0.39	Akr1d1	aldo-keto reductase family 1, member D1	19372	0.21
chr2_58765113_58765779	0.39	Upp2	uridine phosphorylase 2	121	0.97
chr10_87904063_87904214	0.39	Igf1os	insulin-like growth factor 1, opposite strand	40757	0.13
chr3_138236871_138237032	0.39	4930579F01Rik	RIKEN cDNA 4930579F01 gene	2712	0.17

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox8

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.8	GO:0006526	arginine biosynthetic process(GO:0006526)
0.2	0.7	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.6	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.2	0.6	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.2	0.7	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.2	0.6	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.6	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.1	0.3	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	1.6	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.6	GO:0030050	vesicle transport along actin filament(GO:0030050)
0.1	0.4	GO:0006481	C-terminal protein methylation(GO:0006481)
0.1	0.4	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1	0.4	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.5	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.1	0.5	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.5	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.6	GO:1902222	L-phenylalanine metabolic process(GO:0006558) L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.1	0.4	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	0.3	GO:0006553	lysine metabolic process(GO:0006553)
0.1	0.3	GO:0035694	mitochondrial protein catabolic process(GO:0035694)
0.1	0.4	GO:0046449	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.3	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.1	0.8	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.1	0.6	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.1	0.4	GO:0098789	pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1	0.2	GO:1903677	regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.1	0.6	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.1	0.2	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.1	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.1	0.3	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.1	0.2	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.1	0.4	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.1	0.1	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1	0.4	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.1	0.3	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.1	0.2	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.2	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.1	0.2	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1	0.2	GO:0055099	response to high density lipoprotein particle(GO:0055099)
0.1	0.2	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.3	GO:0003383	apical constriction(GO:0003383)
0.1	0.2	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.1	0.2	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.1	0.2	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.1	0.4	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.5	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.1	0.2	GO:0038028	insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.1	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.1	0.2	GO:0015747	urate transport(GO:0015747)
0.1	0.2	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.1	0.3	GO:0072602	interleukin-4 secretion(GO:0072602)
0.1	0.1	GO:0035973	aggrephagy(GO:0035973)
0.1	0.2	GO:0035754	B cell chemotaxis(GO:0035754)
0.1	0.2	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.1	0.4	GO:0070857	regulation of bile acid biosynthetic process(GO:0070857)
0.1	0.2	GO:0006210	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.1	GO:0045917	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	0.2	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1	0.2	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.1	0.4	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.1	0.2	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.2	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.5	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.1	GO:0048371	lateral mesoderm morphogenesis(GO:0048369) lateral mesoderm formation(GO:0048370) lateral mesodermal cell differentiation(GO:0048371)
0.0	0.0	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.3	GO:2000672	negative regulation of motor neuron apoptotic process(GO:2000672)
0.0	0.2	GO:0032819	positive regulation of natural killer cell proliferation(GO:0032819)
0.0	0.3	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.2	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.2	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.1	GO:0006680	glucosylceramide catabolic process(GO:0006680)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.2	GO:0061684	chaperone-mediated autophagy(GO:0061684)
0.0	0.1	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	1.1	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.3	GO:0000012	single strand break repair(GO:0000012)
0.0	0.2	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.7	GO:0031116	positive regulation of microtubule polymerization(GO:0031116)
0.0	0.2	GO:0051574	positive regulation of histone H3-K9 methylation(GO:0051574)
0.0	0.1	GO:0098700	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.2	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:1901856	negative regulation of cellular respiration(GO:1901856)
0.0	0.2	GO:0070562	regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0	0.3	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.0	0.3	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.1	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.2	GO:0007567	parturition(GO:0007567)
0.0	0.0	GO:0021747	cochlear nucleus development(GO:0021747)
0.0	0.5	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.2	GO:1903799	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.1	GO:0033615	mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.1	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.3	GO:0060136	embryonic process involved in female pregnancy(GO:0060136)
0.0	0.1	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.2	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.1	GO:0071042	nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0	0.1	GO:0070634	transepithelial ammonium transport(GO:0070634)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.1	GO:0070682	proteasome regulatory particle assembly(GO:0070682)
0.0	0.2	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.3	GO:0006699	bile acid biosynthetic process(GO:0006699)
0.0	0.2	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.0	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.1	GO:0071596	ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0	0.2	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.1	GO:0009174	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.1	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0035622	intrahepatic bile duct development(GO:0035622)
0.0	0.2	GO:0046874	quinolinate metabolic process(GO:0046874)
0.0	0.2	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.4	GO:0003334	keratinocyte development(GO:0003334)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.1	GO:0046477	glycosylceramide catabolic process(GO:0046477)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:2000302	positive regulation of synaptic vesicle exocytosis(GO:2000302)
0.0	0.0	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.1	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0	0.1	GO:0048597	post-embryonic camera-type eye morphogenesis(GO:0048597)
0.0	0.3	GO:0031468	nuclear envelope reassembly(GO:0031468)
0.0	0.2	GO:0048539	bone marrow development(GO:0048539)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0021764	amygdala development(GO:0021764)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.0	0.1	GO:0002154	thyroid hormone mediated signaling pathway(GO:0002154) regulation of thyroid hormone mediated signaling pathway(GO:0002155)
0.0	0.1	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.2	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.0	GO:0003223	ventricular compact myocardium morphogenesis(GO:0003223)
0.0	0.1	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.2	GO:1902902	negative regulation of autophagosome assembly(GO:1902902)
0.0	0.0	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.1	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.1	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.2	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.0	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.0	GO:0048793	pronephros development(GO:0048793)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.0	GO:0038086	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.0	0.1	GO:0006048	UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0	0.1	GO:0090205	positive regulation of cholesterol biosynthetic process(GO:0045542) positive regulation of cholesterol metabolic process(GO:0090205)
0.0	0.1	GO:1901096	regulation of autophagosome maturation(GO:1901096)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0050717	positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.0	0.0	GO:2000680	regulation of rubidium ion transport(GO:2000680)
0.0	0.1	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0	0.1	GO:0021570	rhombomere 4 development(GO:0021570)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0006931	substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0	0.0	GO:2000409	regulation of T cell extravasation(GO:2000407) positive regulation of T cell extravasation(GO:2000409)
0.0	0.0	GO:0070318	positive regulation of G0 to G1 transition(GO:0070318)
0.0	0.0	GO:1903300	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0002091	negative regulation of receptor internalization(GO:0002091)
0.0	0.1	GO:0046959	habituation(GO:0046959)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.0	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.2	GO:0007253	cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0	0.1	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.7	GO:0000381	regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0	0.3	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.0	GO:0010963	regulation of L-arginine import(GO:0010963)
0.0	0.3	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006742	NADP catabolic process(GO:0006742)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.1	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.2	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.0	GO:0072223	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0	0.2	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.0	GO:0010536	positive regulation of activation of Janus kinase activity(GO:0010536)
0.0	0.2	GO:0034497	protein localization to pre-autophagosomal structure(GO:0034497)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.1	GO:0072497	mesenchymal stem cell differentiation(GO:0072497)
0.0	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.0	0.1	GO:0048478	replication fork protection(GO:0048478)
0.0	0.1	GO:0021684	cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0	0.2	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0050932	regulation of pigment cell differentiation(GO:0050932)
0.0	0.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:0045852	pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0	0.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.1	GO:0006362	transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.1	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.2	GO:0051767	nitric-oxide synthase biosynthetic process(GO:0051767) regulation of nitric-oxide synthase biosynthetic process(GO:0051769) positive regulation of nitric-oxide synthase biosynthetic process(GO:0051770)
0.0	0.1	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.2	GO:0002329	pre-B cell differentiation(GO:0002329)
0.0	0.2	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0006295	nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0	0.0	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.0	0.1	GO:0046066	purine deoxyribonucleoside diphosphate metabolic process(GO:0009182) dGDP metabolic process(GO:0046066)
0.0	0.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.0	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0060020	Bergmann glial cell differentiation(GO:0060020)
0.0	0.0	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.0	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.4	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.0	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0006449	regulation of translational termination(GO:0006449)
0.0	0.0	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	0.2	GO:0032986	nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:1900164	nodal signaling pathway involved in determination of left/right asymmetry(GO:0038107) regulation of transcription from RNA polymerase II promoter involved in determination of left/right symmetry(GO:1900094) nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900164)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.1	GO:0001955	blood vessel maturation(GO:0001955)
0.0	0.1	GO:0045722	positive regulation of gluconeogenesis(GO:0045722)
0.0	0.0	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.1	GO:0060628	regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0	0.1	GO:0009109	coenzyme catabolic process(GO:0009109)
0.0	0.0	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:1905097	regulation of guanyl-nucleotide exchange factor activity(GO:1905097)
0.0	0.1	GO:0045448	regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0	0.1	GO:0003199	endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0	0.0	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0032959	inositol trisphosphate biosynthetic process(GO:0032959)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.0	GO:0032286	central nervous system myelin maintenance(GO:0032286)
0.0	0.0	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0060087	relaxation of vascular smooth muscle(GO:0060087)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.0	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.0	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.0	GO:0006290	pyrimidine dimer repair(GO:0006290)
0.0	0.1	GO:0050916	sensory perception of sweet taste(GO:0050916)
0.0	0.1	GO:1904491	protein localization to ciliary transition zone(GO:1904491)
0.0	0.3	GO:0070542	response to fatty acid(GO:0070542)
0.0	0.0	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.0	GO:0097112	gamma-aminobutyric acid receptor clustering(GO:0097112)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.2	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.1	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:1902236	negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.2	GO:1902187	negative regulation of viral release from host cell(GO:1902187)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.1	GO:0006591	ornithine metabolic process(GO:0006591)
0.0	0.0	GO:0046607	positive regulation of centrosome duplication(GO:0010825) positive regulation of centrosome cycle(GO:0046607)
0.0	0.1	GO:0019509	L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0	0.1	GO:0009414	response to water deprivation(GO:0009414)
0.0	0.0	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.0	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.0	GO:0021882	regulation of transcription from RNA polymerase II promoter involved in forebrain neuron fate commitment(GO:0021882)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0097500	receptor localization to nonmotile primary cilium(GO:0097500)
0.0	0.0	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.0	0.1	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.1	GO:0007144	female meiosis I(GO:0007144)
0.0	0.1	GO:0046655	folic acid metabolic process(GO:0046655)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.0	GO:0048143	astrocyte activation(GO:0048143)
0.0	0.0	GO:0098787	mRNA cleavage involved in mRNA processing(GO:0098787)
0.0	0.0	GO:0090160	Golgi to lysosome transport(GO:0090160)
0.0	0.1	GO:0006388	RNA splicing, via endonucleolytic cleavage and ligation(GO:0000394) tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0	0.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.0	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0	0.0	GO:0072309	mesenchymal stem cell maintenance involved in metanephric nephron morphogenesis(GO:0072309)
0.0	0.0	GO:1904398	positive regulation of receptor clustering(GO:1903911) positive regulation of neuromuscular junction development(GO:1904398)
0.0	0.1	GO:0040015	negative regulation of multicellular organism growth(GO:0040015)
0.0	0.2	GO:0006085	acetyl-CoA biosynthetic process(GO:0006085)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.5	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.0	GO:0090135	actin filament branching(GO:0090135)
0.0	0.0	GO:0071360	cellular response to exogenous dsRNA(GO:0071360)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.0	GO:0006269	DNA replication, synthesis of RNA primer(GO:0006269)
0.0	0.0	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.0	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.0	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.0	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0	0.1	GO:0006122	mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.0	0.4	GO:0048536	spleen development(GO:0048536)
0.0	0.3	GO:0032728	positive regulation of interferon-beta production(GO:0032728)
0.0	0.0	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:0002024	diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0	0.0	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.0	0.0	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.0	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.0	GO:0006772	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:0051131	chaperone-mediated protein complex assembly(GO:0051131)
0.0	0.1	GO:0097320	membrane tubulation(GO:0097320)
0.0	0.0	GO:0046060	dATP metabolic process(GO:0046060)
0.0	0.1	GO:1903975	regulation of glial cell migration(GO:1903975)
0.0	0.0	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
0.0	0.1	GO:0007202	activation of phospholipase C activity(GO:0007202)
0.0	0.1	GO:0022417	protein maturation by protein folding(GO:0022417)
0.0	0.0	GO:0009128	purine nucleoside monophosphate catabolic process(GO:0009128)
0.0	0.0	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.1	GO:0051138	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0	0.0	GO:0016321	female meiosis chromosome segregation(GO:0016321)
0.0	0.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.0	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.1	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.2	GO:0001976	neurological system process involved in regulation of systemic arterial blood pressure(GO:0001976)
0.0	0.0	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.0	0.0	GO:0032482	Rab protein signal transduction(GO:0032482)
0.0	0.2	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.0	GO:0014891	striated muscle atrophy(GO:0014891)
0.0	0.0	GO:0006570	tyrosine metabolic process(GO:0006570)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.2	0.6	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.6	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0097443	sorting endosome(GO:0097443)
0.1	0.3	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	0.2	GO:0070545	PeBoW complex(GO:0070545)
0.1	0.2	GO:0044316	cone cell pedicle(GO:0044316)
0.1	0.6	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.2	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.3	GO:0001739	sex chromatin(GO:0001739)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.7	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.4	GO:0034518	mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0	0.1	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0097413	Lewy body(GO:0097413)
0.0	0.2	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.4	GO:0031143	pseudopodium(GO:0031143)
0.0	0.6	GO:0035371	microtubule plus-end(GO:0035371)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.3	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.3	GO:0071782	endoplasmic reticulum tubular network(GO:0071782)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.3	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.6	GO:0097440	apical dendrite(GO:0097440)
0.0	0.2	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.2	GO:0005579	membrane attack complex(GO:0005579)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.4	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.4	GO:0005682	U5 snRNP(GO:0005682)
0.0	0.2	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	1.1	GO:0005788	endoplasmic reticulum lumen(GO:0005788)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.2	GO:0000808	origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0	0.9	GO:0014704	intercalated disc(GO:0014704)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.2	GO:0036128	CatSper complex(GO:0036128)
0.0	0.9	GO:0042645	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.0	GO:1903349	omegasome membrane(GO:1903349)
0.0	0.0	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:1990726	Lsm1-7-Pat1 complex(GO:1990726)
0.0	0.4	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.0	GO:0046691	intracellular canaliculus(GO:0046691)
0.0	0.0	GO:0042827	platelet dense granule(GO:0042827)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.2	GO:0000177	cytoplasmic exosome (RNase complex)(GO:0000177)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0035098	ESC/E(Z) complex(GO:0035098)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0000506	glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0	0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0005583	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0	0.2	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.0	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.2	GO:0032839	dendrite cytoplasm(GO:0032839)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.4	GO:0000315	organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0	0.0	GO:0016939	kinesin II complex(GO:0016939)
0.0	0.1	GO:0045275	mitochondrial respiratory chain complex III(GO:0005750) respiratory chain complex III(GO:0045275)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0032593	insulin-responsive compartment(GO:0032593)
0.0	0.1	GO:0005744	mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.0	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.2	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.0	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.0	GO:0031417	NatC complex(GO:0031417)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.3	0.5	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.2	0.7	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.6	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.2	0.6	GO:0004771	sterol esterase activity(GO:0004771)
0.2	0.5	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.1	0.7	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.4	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.5	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.4	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	0.5	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.1	1.0	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.4	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.3	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0034056	estrogen response element binding(GO:0034056)
0.1	0.3	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.1	0.2	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.1	0.4	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.2	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.1	0.3	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.2	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.1	0.3	GO:0051525	NFAT protein binding(GO:0051525)
0.1	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.4	GO:0043295	glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.2	GO:0070728	leucine binding(GO:0070728)
0.0	0.2	GO:0004144	diacylglycerol O-acyltransferase activity(GO:0004144)
0.0	0.2	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	1.0	GO:0052713	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.3	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.2	GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0	0.2	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.4	GO:0042043	neurexin family protein binding(GO:0042043)
0.0	0.1	GO:0015143	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.3	GO:0050321	tau-protein kinase activity(GO:0050321)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.5	GO:0004089	carbonate dehydratase activity(GO:0004089)
0.0	0.3	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.5	GO:0004708	MAP kinase kinase activity(GO:0004708)
0.0	0.1	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.6	GO:0016922	ligand-dependent nuclear receptor binding(GO:0016922)
0.0	0.1	GO:0017176	phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.0	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.1	GO:0008158	hedgehog receptor activity(GO:0008158)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	1.1	GO:0008392	arachidonic acid epoxygenase activity(GO:0008392)
0.0	0.0	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.1	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0031544	peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.1	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.3	GO:0070569	uridylyltransferase activity(GO:0070569)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.2	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	0.6	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.1	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.0	0.3	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0071253	connexin binding(GO:0071253)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.0	GO:0050051	leukotriene-B4 20-monooxygenase activity(GO:0050051)
0.0	0.2	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0050815	phosphoserine binding(GO:0050815)
0.0	0.0	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.7	GO:0047376	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0003917	DNA topoisomerase type I activity(GO:0003917)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.4	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.1	GO:0031686	A1 adenosine receptor binding(GO:0031686)
0.0	0.2	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0	0.0	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.2	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.1	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.1	GO:0046404	ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0004308	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0	0.0	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.4	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.2	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0005134	interleukin-2 receptor binding(GO:0005134)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.3	GO:0016646	oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.1	GO:0003910	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.0	0.1	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0043495	protein anchor(GO:0043495)
0.0	0.4	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.3	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	0.0	GO:0050253	retinyl-palmitate esterase activity(GO:0050253)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0032557	pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) pyrimidine ribonucleoside binding(GO:0032551) pyrimidine ribonucleotide binding(GO:0032557)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.3	GO:0005521	lamin binding(GO:0005521)
0.0	0.0	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.5	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.0	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.0	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.5	GO:0042169	SH2 domain binding(GO:0042169)
0.0	0.0	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.0	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0004556	alpha-amylase activity(GO:0004556)
0.0	0.1	GO:0038100	nodal binding(GO:0038100)
0.0	0.0	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.0	GO:0030619	U1 snRNA binding(GO:0030619)
0.0	0.3	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.1	GO:0004859	phospholipase inhibitor activity(GO:0004859)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.0	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.2	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.4	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.4	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0	0.2	GO:0070402	NADPH binding(GO:0070402)
0.0	0.0	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.1	GO:0030306	ADP-ribosylation factor binding(GO:0030306)
0.0	0.0	GO:0070990	snRNP binding(GO:0070990)
0.0	0.1	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.2	GO:0042974	retinoic acid receptor binding(GO:0042974)
0.0	0.4	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0008312	7S RNA binding(GO:0008312)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.0	GO:0005176	ErbB-2 class receptor binding(GO:0005176)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0005275	amine transmembrane transporter activity(GO:0005275)
0.0	0.1	GO:0008474	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0004169	dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0004579	dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0	0.0	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.0	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.2	GO:0019215	intermediate filament binding(GO:0019215)
0.0	0.0	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0016670	oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0	0.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:0001163	RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0	0.2	GO:0030552	cAMP binding(GO:0030552)
0.0	0.0	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0015194	L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.0	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.3	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.1	GO:0008079	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.0	GO:0098847	sequence-specific single stranded DNA binding(GO:0098847)
0.0	0.0	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.0	0.0	GO:0008948	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) oxaloacetate decarboxylase activity(GO:0008948)
0.0	0.1	GO:0003993	acid phosphatase activity(GO:0003993)
0.0	0.1	GO:0003688	DNA replication origin binding(GO:0003688)
0.0	0.0	GO:0008821	crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0	0.0	GO:0004706	JUN kinase kinase kinase activity(GO:0004706)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.1	GO:0005138	interleukin-6 receptor binding(GO:0005138)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.1	1.5	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	1.7	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.6	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.0	0.7	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.0	0.7	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.5	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.8	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.7	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.1	PID ARF6 PATHWAY	Arf6 signaling events
0.0	0.5	PID AURORA B PATHWAY	Aurora B signaling
0.0	0.1	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.0	0.4	ST PHOSPHOINOSITIDE 3 KINASE PATHWAY	PI3K Pathway
0.0	0.2	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling
0.0	0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.4	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.1	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.2	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.0	0.1	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.4	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.1	NABA COLLAGENS	Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.7	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.1	1.0	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	0.1	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.0	0.1	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.5	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.5	REACTOME PROCESSING OF INTRONLESS PRE MRNAS	Genes involved in Processing of Intronless Pre-mRNAs
0.0	0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.0	0.3	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.0	0.3	REACTOME ER PHAGOSOME PATHWAY	Genes involved in ER-Phagosome pathway
0.0	0.8	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.4	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.7	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.5	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	0.4	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.4	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.5	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.0	0.1	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.1	REACTOME AQUAPORIN MEDIATED TRANSPORT	Genes involved in Aquaporin-mediated transport
0.0	0.4	REACTOME GLYCOLYSIS	Genes involved in Glycolysis
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.3	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.1	REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Dopamine Neurotransmitter Release Cycle
0.0	0.2	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.0	0.0	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.0	0.5	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME TIE2 SIGNALING	Genes involved in Tie2 Signaling
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules
0.0	0.3	REACTOME DOUBLE STRAND BREAK REPAIR	Genes involved in Double-Strand Break Repair
0.0	0.0	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.4	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.1	REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX	Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0	0.1	REACTOME CDT1 ASSOCIATION WITH THE CDC6 ORC ORIGIN COMPLEX	Genes involved in CDT1 association with the CDC6:ORC:origin complex
0.0	0.1	REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS	Genes involved in Apoptotic cleavage of cellular proteins
0.0	0.1	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME IL1 SIGNALING	Genes involved in Interleukin-1 signaling
0.0	0.2	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.2	REACTOME FORMATION OF INCISION COMPLEX IN GG NER	Genes involved in Formation of incision complex in GG-NER
0.0	0.0	REACTOME RECYCLING OF BILE ACIDS AND SALTS	Genes involved in Recycling of bile acids and salts
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	2.1	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.2	REACTOME INTERACTION BETWEEN L1 AND ANKYRINS	Genes involved in Interaction between L1 and Ankyrins
0.0	0.2	REACTOME PKB MEDIATED EVENTS	Genes involved in PKB-mediated events
0.0	0.2	REACTOME INSULIN SYNTHESIS AND PROCESSING	Genes involved in Insulin Synthesis and Processing
0.0	0.1	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.3	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.5	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME G2 M DNA DAMAGE CHECKPOINT	Genes involved in G2/M DNA damage checkpoint
0.0	0.1	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1	Genes involved in Signaling by activated point mutants of FGFR1
0.0	0.1	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI	Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0	0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.0	0.1	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha

Results for Sox8

Z-value: 2.03

Motif logo

Transcription factors associated with Sox8

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Sox8 motif across conditions

Conditions sorted by the z-value of the Sox8 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox8

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: