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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Sp2

Z-value: 1.04

Motif logo

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Transcription factors associated with Sp2

Gene Symbol Gene ID Gene Info
Sp2
ENSMUSG00000018678.6 Sp2 transcription factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr11_96967452_96967847Sp210160.330273-0.862.7e-02Click!
chr11_96976103_96976321Sp214990.2184520.824.8e-02Click!
chr11_96963893_96964044Sp246970.100484-0.691.3e-01Click!
chr11_96977958_96978364Sp24500.6622780.631.8e-01Click!
chr11_96982500_96982661Sp23790.722182-0.621.9e-01Click!

Activity of the Sp2 motif across conditions

Conditions sorted by the z-value of the Sp2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_98767825_98767976 0.78 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 2526
 0.15
chr4_136090324_136090475 0.78 Gm13009
 predicted gene 13009
 15427
 0.12
chr11_98767109_98767369 0.77 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 3187
 0.13
chr3_121982194_121982345 0.57 Arhgap29
 Rho GTPase activating protein 29
 719
 0.68
chr10_75835778_75835936 0.50 Gstt2
 glutathione S-transferase, theta 2
 976
 0.36
chr8_119417830_119417981 0.45 Osgin1
 oxidative stress induced growth inhibitor 1
 16219
 0.14
chr6_145865476_145865643 0.44 Bhlhe41
 basic helix-loop-helix family, member e41
 1
 0.97
chr6_145855716_145856207 0.44 Gm43909
 predicted gene, 43909
 7336
 0.17
chr18_21300208_21300569 0.43 Garem1
 GRB2 associated regulator of MAPK1 subtype 1
 250
 0.91
chr16_45945391_45945574 0.42 Gm15638
 predicted gene 15638
 124
 0.96
chr7_127477990_127478144 0.40 Fbrs
 fibrosin
 1132
 0.21
chr8_122497127_122497278 0.38 Piezo1
 piezo-type mechanosensitive ion channel component 1
 1002
 0.33
chr2_25983198_25983706 0.36 Camsap1
 calmodulin regulated spectrin-associated protein 1
 170
 0.93
chr18_64265864_64266047 0.35 St8sia3
 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
 31
 0.97
chr8_108710919_108711070 0.34 Zfhx3
 zinc finger homeobox 3
 3650
 0.29
chr9_74875936_74876087 0.33 Onecut1
 one cut domain, family member 1
 9527
 0.15
chr1_74807002_74807292 0.31 Wnt10a
 wingless-type MMTV integration site family, member 10A
 13784
 0.11
chr11_95032963_95033336 0.31 Gm11513
 predicted gene 11513
 390
 0.76
chr5_107260769_107260925 0.31 Gm42900
 predicted gene 42900
 4343
 0.17
chr17_86165279_86165510 0.30 Prkce
 protein kinase C, epsilon
 2391
 0.3
chr11_98953496_98953709 0.30 Rara
 retinoic acid receptor, alpha
 6810
 0.11
chr18_34864196_34864456 0.30 Egr1
 early growth response 1
 3119
 0.18
chr8_72492767_72492930 0.29 Gm17435
 predicted gene, 17435
 86
 0.69
chr5_121836951_121837292 0.29 Sh2b3
 SH2B adaptor protein 3
 262
 0.83
chr11_117875729_117875880 0.28 Tha1
 threonine aldolase 1
 2323
 0.16
chr6_137142914_137143065 0.28 Rerg
 RAS-like, estrogen-regulated, growth-inhibitor
 2926
 0.27
chr12_105008860_105009027 0.28 Syne3
 spectrin repeat containing, nuclear envelope family member 3
 866
 0.44
chr19_57877445_57877626 0.27 Mir5623
 microRNA 5623
 173632
 0.03
chr13_109485029_109485208 0.26 Pde4d
 phosphodiesterase 4D, cAMP specific
 42935
 0.21
chr12_86836691_86837004 0.26 Gm10095
 predicted gene 10095
 9620
 0.19
chr4_149393707_149393902 0.26 Ube4b
 ubiquitination factor E4B
 5574
 0.15
chr16_31452530_31452681 0.25 Bdh1
 3-hydroxybutyrate dehydrogenase, type 1
 5511
 0.15
chr3_41580995_41581174 0.25 Jade1
 jade family PHD finger 1
 228
 0.92
chr6_121064341_121064666 0.25 Gm4651
 predicted gene 4651
 39
 0.97
chr18_34511486_34511736 0.25 n-R5s24
 nuclear encoded rRNA 5S 24
 1874
 0.27
chr9_24774302_24774460 0.24 Tbx20
 T-box 20
 78
 0.97
chr19_7196833_7197251 0.24 Otub1
 OTU domain, ubiquitin aldehyde binding 1
 3422
 0.16
chr7_25249677_25249858 0.24 Erf
 Ets2 repressor factor
 963
 0.32
chr1_9967919_9968070 0.24 Tcf24
 transcription factor 24
 62
 0.9
chr15_102029131_102029282 0.23 Krt18
 keratin 18
 1026
 0.4
chr3_142749520_142749995 0.23 Gm15540
 predicted gene 15540
 5076
 0.14
chr11_62076764_62076946 0.23 Specc1
 sperm antigen with calponin homology and coiled-coil domains 1
 140
 0.96
chr1_34389167_34389350 0.23 Gm5266
 predicted gene 5266
 21887
 0.09
chr8_45631075_45631340 0.23 Sorbs2
 sorbin and SH3 domain containing 2
 3006
 0.26
chr14_45056454_45056605 0.23 Gm21010
 predicted gene, 21010
 34086
 0.09
chr11_89937352_89937519 0.23 Pctp
 phosphatidylcholine transfer protein
 65459
 0.12
chr2_29973635_29973786 0.23 Sptan1
 spectrin alpha, non-erythrocytic 1
 4670
 0.13
chr9_107675603_107675819 0.23 Gnat1
 guanine nucleotide binding protein, alpha transducing 1
 730
 0.43
chr7_45053316_45053568 0.23 Prr12
 proline rich 12
 561
 0.42
chr9_62351261_62351449 0.23 Anp32a
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 6556
 0.21
chr1_175692768_175692950 0.22 Chml
 choroideremia-like
 42
 0.54
chr9_42507207_42507377 0.22 Tbcel
 tubulin folding cofactor E-like
 517
 0.81
chr8_84723608_84723805 0.22 G430095P16Rik
 RIKEN cDNA G430095P16 gene
 699
 0.52
chr2_128817774_128817954 0.22 Tmem87b
 transmembrane protein 87B
 254
 0.9
chr5_88796583_88796899 0.22 Gm42912
 predicted gene 42912
 2845
 0.21
chr11_109611461_109611655 0.22 Wipi1
 WD repeat domain, phosphoinositide interacting 1
 126
 0.95
chr9_121380419_121380796 0.22 Trak1
 trafficking protein, kinesin binding 1
 2187
 0.29
chr8_70539199_70539597 0.22 Ell
 elongation factor RNA polymerase II
 59
 0.94
chr15_101266552_101266884 0.21 Nr4a1
 nuclear receptor subfamily 4, group A, member 1
 128
 0.93
chr9_25455109_25455478 0.21 Gm8049
 predicted gene 8049
 4831
 0.23
chrX_100447058_100447240 0.21 Awat2
 acyl-CoA wax alcohol acyltransferase 2
 4432
 0.18
chr6_113306564_113306942 0.21 Gm43935
 predicted gene, 43935
 79
 0.8
chr11_76911521_76911684 0.21 Tmigd1
 transmembrane and immunoglobulin domain containing 1
 7040
 0.17
chr15_97029364_97029596 0.21 Slc38a4
 solute carrier family 38, member 4
 1731
 0.48
chr7_26833022_26833239 0.20 Cyp2a5
 cytochrome P450, family 2, subfamily a, polypeptide 5
 2175
 0.27
chr15_27444899_27445331 0.20 Gm36899
 predicted gene, 36899
 18334
 0.16
chr16_4586554_4586882 0.20 Glis2
 GLIS family zinc finger 2
 7995
 0.13
chr10_87020834_87020985 0.20 Stab2
 stabilin 2
 12884
 0.16
chr17_7415036_7415292 0.20 Gm6553
 predicted gene 6553
 15078
 0.15
chr7_26781568_26782082 0.20 Cyp2b19
 cytochrome P450, family 2, subfamily b, polypeptide 19
 15270
 0.15
chr2_118874175_118874326 0.20 Ivd
 isovaleryl coenzyme A dehydrogenase
 57
 0.96
chr15_66968663_66969063 0.20 Gm2895
 predicted gene 2895
 460
 0.61
chr5_3596102_3596444 0.19 Rbm48
 RNA binding motif protein 48
 71
 0.49
chr5_111509241_111509406 0.19 C130026L21Rik
 RIKEN cDNA C130026L21 gene
 72099
 0.08
chr15_99865164_99865320 0.19 Lima1
 LIM domain and actin binding 1
 9429
 0.08
chr8_12193585_12193751 0.19 A230072I06Rik
 RIKEN cDNA A230072I06 gene
 85151
 0.08
chr2_32661930_32662135 0.19 Mir1954
 microRNA 1954
 9703
 0.07
chr6_94701073_94701362 0.19 Lrig1
 leucine-rich repeats and immunoglobulin-like domains 1
 1059
 0.59
chr12_85350868_85351019 0.19 Tmed10
 transmembrane p24 trafficking protein 10
 23
 0.96
chr5_139803654_139803817 0.19 Tmem184a
 transmembrane protein 184a
 4245
 0.14
chr4_131041255_131041582 0.19 A930031H19Rik
 RIKEN cDNA A930031H19 gene
 30944
 0.18
chr18_60748821_60749236 0.19 Ndst1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 378
 0.77
chr11_16832225_16832426 0.19 Egfros
 epidermal growth factor receptor, opposite strand
 1623
 0.42
chr1_45856082_45856244 0.19 Gm5526
 predicted pseudogene 5526
 1591
 0.29
chr1_160904144_160904325 0.19 Rc3h1
 RING CCCH (C3H) domains 1
 2184
 0.15
chr1_46854072_46854237 0.19 Slc39a10
 solute carrier family 39 (zinc transporter), member 10
 108
 0.96
chr10_81320539_81320949 0.19 Cactin
 cactin, spliceosome C complex subunit
 359
 0.64
chr5_28079954_28080114 0.18 Insig1
 insulin induced gene 1
 5368
 0.18
chr11_78697801_78698141 0.18 Nlk
 nemo like kinase
 598
 0.68
chr11_16859692_16859843 0.18 Egfr
 epidermal growth factor receptor
 18383
 0.18
chr9_63698782_63698955 0.18 Smad3
 SMAD family member 3
 13101
 0.22
chr3_144570308_144570468 0.18 Selenof
 selenoprotein F
 38
 0.72
chrX_164419325_164419506 0.18 Piga
 phosphatidylinositol glycan anchor biosynthesis, class A
 372
 0.85
chr7_130631856_130632010 0.18 Tacc2
 transforming, acidic coiled-coil containing protein 2
 13548
 0.17
chr7_25267913_25268075 0.18 Cic
 capicua transcriptional repressor
 290
 0.79
chr18_33437665_33437816 0.18 Nrep
 neuronal regeneration related protein
 25695
 0.18
chr8_35077237_35077419 0.17 Gm34419
 predicted gene, 34419
 17217
 0.16
chr5_73256517_73256913 0.17 Fryl
 FRY like transcription coactivator
 96
 0.94
chr8_69774901_69775060 0.17 Zfp866
 zinc finger protein 866
 69
 0.52
chr2_63862186_63862358 0.17 Fign
 fidgetin
 235716
 0.02
chr6_48444394_48444549 0.17 Zfp467
 zinc finger protein 467
 435
 0.7
chr17_47988159_47988330 0.17 Gm14871
 predicted gene 14871
 15328
 0.13
chr9_78528236_78528545 0.17 Gm47430
 predicted gene, 47430
 7844
 0.14
chr14_25456911_25457241 0.17 Zmiz1os1
 Zmiz1 opposite strand 1
 722
 0.52
chr1_169659535_169659755 0.17 Rgs5
 regulator of G-protein signaling 5
 4123
 0.26
chr5_75143316_75143477 0.17 Olfr1401-ps1
 olfactory receptor 1401, pseudogene 1
 1838
 0.21
chr11_53818731_53818912 0.17 Gm12216
 predicted gene 12216
 22946
 0.11
chr6_127152476_127152648 0.17 Ccnd2
 cyclin D2
 369
 0.76
chr1_89107539_89107745 0.17 Gm38312
 predicted gene, 38312
 10569
 0.21
chr6_125165542_125165892 0.17 Gapdh
 glyceraldehyde-3-phosphate dehydrogenase
 56
 0.92
chr7_130098725_130098937 0.16 Gm23847
 predicted gene, 23847
 63737
 0.12
chr16_38376538_38376695 0.16 Popdc2
 popeye domain containing 2
 4618
 0.14
chr3_88425144_88425305 0.16 Slc25a44
 solute carrier family 25, member 44
 85
 0.91
chr1_168380327_168380548 0.16 Gm38381
 predicted gene, 38381
 29629
 0.18
chrX_163958648_163958821 0.16 Zrsr2
 zinc finger (CCCH type), RNA binding motif and serine/arginine rich 2
 73
 0.98
chr4_57675400_57675766 0.16 Pakap
 paralemmin A kinase anchor protein
 37608
 0.18
chr13_72016997_72017161 0.16 Irx1
 Iroquois homeobox 1
 53356
 0.15
chr13_99794055_99794213 0.16 Gm24471
 predicted gene, 24471
 101605
 0.06
chr16_43303328_43303503 0.16 Gm37946
 predicted gene, 37946
 4866
 0.21
chr8_45626757_45627016 0.16 Sorbs2
 sorbin and SH3 domain containing 2
 853
 0.61
chr1_184732600_184732772 0.16 Hlx
 H2.0-like homeobox
 67
 0.96
chr8_124642015_124642295 0.16 2310022B05Rik
 RIKEN cDNA 2310022B05 gene
 21214
 0.14
chr2_93261940_93262145 0.16 Tspan18
 tetraspanin 18
 34256
 0.17
chr13_34814605_34814934 0.16 Gm47157
 predicted gene, 47157
 225
 0.91
chr17_57214462_57214630 0.16 Mir6978
 microRNA 6978
 2682
 0.16
chr9_107650834_107650985 0.16 Slc38a3
 solute carrier family 38, member 3
 5111
 0.08
chr17_7386060_7386243 0.16 Unc93a2
 unc-93 homolog A2
 687
 0.61
chr16_28851482_28851645 0.16 Mb21d2
 Mab-21 domain containing 2
 15196
 0.27
chr2_26445181_26445721 0.16 Sec16a
 SEC16 homolog A, endoplasmic reticulum export factor
 235
 0.47
chr11_59804844_59804999 0.16 Flcn
 folliculin
 4667
 0.11
chr1_134745790_134746030 0.16 Syt2
 synaptotagmin II
 2667
 0.23
chr11_82035273_82035424 0.16 Ccl2
 chemokine (C-C motif) ligand 2
 223
 0.89
chr10_127668046_127668306 0.16 Nab2
 Ngfi-A binding protein 2
 392
 0.62
chr1_91448793_91448944 0.16 Per2
 period circadian clock 2
 997
 0.4
chr12_86478452_86478665 0.16 Esrrb
 estrogen related receptor, beta
 8441
 0.26
chr7_141458231_141458600 0.16 Pnpla2
 patatin-like phospholipase domain containing 2
 1397
 0.16
chr3_68493989_68494284 0.16 Schip1
 schwannomin interacting protein 1
 72
 0.98
chr3_131564564_131564861 0.16 Papss1
 3'-phosphoadenosine 5'-phosphosulfate synthase 1
 56
 0.98
chr5_150911743_150911914 0.16 Gm43298
 predicted gene 43298
 29186
 0.16
chr18_49832250_49832445 0.16 Dmxl1
 Dmx-like 1
 323
 0.9
chr1_132388072_132388223 0.15 Tmcc2
 transmembrane and coiled-coil domains 2
 2171
 0.22
chr5_139730884_139731070 0.15 Micall2
 MICAL-like 2
 1857
 0.27
chr2_131233930_131234100 0.15 Mavs
 mitochondrial antiviral signaling protein
 48
 0.96
chr5_123135984_123136315 0.15 Gm38102
 predicted gene, 38102
 388
 0.65
chr11_51619519_51619707 0.15 Nhp2
 NHP2 ribonucleoprotein
 122
 0.94
chr19_4240260_4240411 0.15 Pold4
 polymerase (DNA-directed), delta 4
 7897
 0.06
chr8_57487862_57488025 0.15 Sap30
 sin3 associated polypeptide
 83
 0.53
chr8_89279548_89279868 0.15 Gm5356
 predicted pseudogene 5356
 92148
 0.09
chr5_134985683_134985851 0.15 Cldn3
 claudin 3
 447
 0.63
chr12_102788080_102788385 0.15 Gm47042
 predicted gene, 47042
 23520
 0.08
chr7_139388680_139389161 0.15 Inpp5a
 inositol polyphosphate-5-phosphatase A
 189
 0.96
chr19_4719341_4719664 0.15 Sptbn2
 spectrin beta, non-erythrocytic 2
 1577
 0.24
chr2_5951260_5951429 0.15 Upf2
 UPF2 regulator of nonsense transcripts homolog (yeast)
 125
 0.96
chr11_87748776_87748945 0.15 Mir142hg
 Mir142 host gene (non-protein coding)
 6717
 0.09
chr5_147017350_147017528 0.15 Lnx2
 ligand of numb-protein X 2
 1596
 0.37
chr19_22304434_22304587 0.15 Gm22506
 predicted gene, 22506
 68892
 0.12
chr6_29347943_29348124 0.15 Calu
 calumenin
 36
 0.96
chr5_122158077_122158391 0.15 Ppp1cc
 protein phosphatase 1 catalytic subunit gamma
 44
 0.96
chr2_165326498_165326660 0.15 Elmo2
 engulfment and cell motility 2
 100
 0.96
chr3_37158282_37158456 0.15 Gm12532
 predicted gene 12532
 24516
 0.11
chr11_45800072_45800231 0.15 F630206G17Rik
 RIKEN cDNA F630206G17 gene
 7936
 0.16
chr10_80139371_80139556 0.15 Cbarp
 calcium channel, voltage-dependent, beta subunit associated regulatory protein
 98
 0.88
chr4_136035578_136036045 0.14 Rpl11
 ribosomal protein L11
 7013
 0.1
chr13_101746090_101746267 0.14 Gm36638
 predicted gene, 36638
 5710
 0.23
chr3_88296917_88297081 0.14 Tsacc
 TSSK6 activating co-chaperone
 0
 0.59
chr4_149854310_149854480 0.14 Gm47301
 predicted gene, 47301
 36631
 0.09
chr19_57360887_57361068 0.14 Fam160b1
 family with sequence similarity 160, member B1
 53
 0.7
chr19_36731141_36731447 0.14 Ppp1r3c
 protein phosphatase 1, regulatory subunit 3C
 5359
 0.23
chr16_20716658_20716809 0.14 Clcn2
 chloride channel, voltage-sensitive 2
 569
 0.44
chr18_58481759_58481942 0.14 Slc27a6
 solute carrier family 27 (fatty acid transporter), member 6
 74407
 0.12
chr1_171344047_171344210 0.14 Nit1
 nitrilase 1
 339
 0.66
chr6_108065232_108065404 0.14 Setmar
 SET domain without mariner transposase fusion
 256
 0.94
chr10_128337509_128337866 0.14 Cs
 citrate synthase
 47
 0.92
chr12_84772846_84773376 0.14 Npc2
 NPC intracellular cholesterol transporter 2
 41
 0.62
chr3_89391856_89392032 0.14 Gm15417
 predicted gene 15417
 26
 0.6
chr13_67060869_67061048 0.14 Gm46440
 predicted gene, 46440
 157
 0.55
chr4_123411950_123412127 0.14 Macf1
 microtubule-actin crosslinking factor 1
 190
 0.94
chr1_39950143_39950310 0.14 Map4k4
 mitogen-activated protein kinase kinase kinase kinase 4
 13929
 0.22
chr1_168432437_168432592 0.14 Pbx1
 pre B cell leukemia homeobox 1
 244
 0.95
chr11_69996851_69997024 0.14 Phf23
 PHD finger protein 23
 4
 0.92
chr11_51494380_51494743 0.14 Col23a1
 collagen, type XXIII, alpha 1
 79871
 0.07
chr6_124481749_124481909 0.14 C1rl
 complement component 1, r subcomponent-like
 11284
 0.09
chr9_72767021_72767358 0.14 Gm27204
 predicted gene 27204
 9036
 0.12
chr11_106512401_106512774 0.14 Gm22711
 predicted gene, 22711
 11342
 0.15
chr10_77864430_77864592 0.14 Tspear
 thrombospondin type laminin G domain and EAR repeats
 71
 0.91
chr10_88507811_88508139 0.14 Chpt1
 choline phosphotransferase 1
 3902
 0.18
chr5_113024342_113024526 0.14 Grk3
 G protein-coupled receptor kinase 3
 8643
 0.14
chr8_34804694_34804863 0.14 Dusp4
 dual specificity phosphatase 4
 2519
 0.32
chr6_94696254_94696442 0.14 Lrig1
 leucine-rich repeats and immunoglobulin-like domains 1
 3789
 0.28
chr5_118332124_118332291 0.14 Gm28563
 predicted gene 28563
 65123
 0.09
chr2_105396213_105396364 0.14 Rcn1
 reticulocalbin 1
 940
 0.67
chr2_73003161_73003312 0.14 Sp3os
 trans-acting transcription factor 3, opposite strand
 15995
 0.14
chr7_28938830_28938981 0.14 Gm44699
 predicted gene 44699
 4623
 0.12
chr5_24941855_24942029 0.14 Prkag2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 32965
 0.13
chr11_40694837_40695013 0.13 Mat2b
 methionine adenosyltransferase II, beta
 62
 0.97
chr13_55211103_55211935 0.13 Nsd1
 nuclear receptor-binding SET-domain protein 1
 22
 0.97
chr5_23890845_23891003 0.13 AC117663.1
 solute carrier family 40 (iron-regulated transporter), member 1 (Slc40a1), pseudogene
 14481
 0.11
chr9_45268129_45268280 0.13 Il10ra
 interleukin 10 receptor, alpha
 942
 0.35
chr5_137339583_137339751 0.13 Gm43012
 predicted gene 43012
 2258
 0.14
chr2_158168887_158169091 0.13 Tgm2
 transglutaminase 2, C polypeptide
 22553
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Sp2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0097503 sialylation(GO:0097503)
0.1 0.2 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.5 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.2 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 0.2 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.2 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1 0.1 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.2 GO:0071376 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0 0.2 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0002434 immune complex clearance(GO:0002434)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:1902373 negative regulation of mRNA catabolic process(GO:1902373)
0.0 0.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.0 GO:0032907 transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.0 0.1 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.1 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0002254 kinin cascade(GO:0002254)
0.0 0.1 GO:1902956 regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0051365 cellular response to potassium ion starvation(GO:0051365)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0061010 gall bladder development(GO:0061010)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:1901674 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0 0.3 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 0.2 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0003415 chondrocyte hypertrophy(GO:0003415)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.2 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.0 GO:1901671 positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.1 GO:0060214 endocardium formation(GO:0060214)
0.0 0.2 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0 0.2 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.0 0.1 GO:1902309 negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.1 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0071276 cellular response to cadmium ion(GO:0071276)
0.0 0.1 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.0 0.1 GO:0072262 metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.0 0.1 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 0.1 GO:0032513 negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.0 0.1 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0046084 adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0048295 positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.4 GO:0030325 adrenal gland development(GO:0030325)
0.0 0.1 GO:0090579 transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0 0.1 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.0 0.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.1 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.0 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.1 GO:0003347 epicardial cell to mesenchymal cell transition(GO:0003347)
0.0 0.2 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.1 GO:0000710 meiotic mismatch repair(GO:0000710)
0.0 0.1 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.0 0.6 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.0 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.1 GO:0046951 ketone body biosynthetic process(GO:0046951)
0.0 0.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 0.1 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.0 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 0.1 GO:0035435 phosphate ion transmembrane transport(GO:0035435)
0.0 0.0 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.1 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.0 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.1 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0033136 serine phosphorylation of STAT3 protein(GO:0033136)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0060534 trachea cartilage development(GO:0060534)
0.0 0.0 GO:1901856 negative regulation of cellular respiration(GO:1901856)
0.0 0.0 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.0 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.0 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0 0.0 GO:0090219 negative regulation of lipid kinase activity(GO:0090219)
0.0 0.0 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.1 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.1 GO:0018344 protein geranylgeranylation(GO:0018344)
0.0 0.0 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.0 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0048069 eye pigmentation(GO:0048069)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.0 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.2 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:2001185 regulation of CD8-positive, alpha-beta T cell activation(GO:2001185)
0.0 0.1 GO:0046218 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0 0.2 GO:0015936 coenzyme A metabolic process(GO:0015936)
0.0 0.0 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.1 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.0 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.0 GO:0032025 response to cobalt ion(GO:0032025)
0.0 0.0 GO:0033629 negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.0 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.1 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.0 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.0 GO:0033762 response to glucagon(GO:0033762)
0.0 0.0 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.1 GO:0097284 hepatocyte apoptotic process(GO:0097284)
0.0 0.0 GO:0009838 abscission(GO:0009838)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.0 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.0 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.0 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.0 GO:0051572 negative regulation of histone H3-K4 methylation(GO:0051572)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.0 0.0 GO:0002870 lymphocyte anergy(GO:0002249) regulation of T cell anergy(GO:0002667) T cell anergy(GO:0002870) regulation of lymphocyte anergy(GO:0002911)
0.0 0.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.0 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0006851 mitochondrial calcium ion transport(GO:0006851)
0.0 0.0 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.0 0.0 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.0 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.0 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.0 GO:0030202 heparin metabolic process(GO:0030202)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.1 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.2 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 0.2 GO:0097452 GAIT complex(GO:0097452)
0.1 0.2 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.2 GO:0035363 histone locus body(GO:0035363)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0005606 laminin-1 complex(GO:0005606)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.2 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.2 GO:0001650 fibrillar center(GO:0001650)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.0 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.0 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.0 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0097413 Lewy body(GO:0097413)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.0 GO:0033269 internode region of axon(GO:0033269)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0043426 MRF binding(GO:0043426)
0.1 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.1 0.2 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004046 aminoacylase activity(GO:0004046)
0.0 0.1 GO:0016149 translation release factor activity, codon specific(GO:0016149)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.0 GO:0015440 peptide-transporting ATPase activity(GO:0015440)
0.0 0.3 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.1 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.0 0.1 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0008158 hedgehog receptor activity(GO:0008158)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.1 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004445 inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0 0.1 GO:0052724 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0032564 dATP binding(GO:0032564)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.4 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.3 GO:0052890 oxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor(GO:0052890)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.1 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.1 GO:0016899 oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.0 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.0 GO:0034893 mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0 0.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.2 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.0 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.0 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.0 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.0 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.0 0.4 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.0 0.4 GO:0030507 spectrin binding(GO:0030507)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.0 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.0 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.1 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.4 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.0 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.2 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.1 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.7 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.1 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.4 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.0 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.1 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.2 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 0.1 REACTOME OPSINS Genes involved in Opsins
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.2 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.3 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME GAB1 SIGNALOSOME Genes involved in GAB1 signalosome
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.0 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.1 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.1 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.0 0.0 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism