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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Srf

Z-value: 2.15

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Transcription factors associated with Srf

Gene Symbol	Gene ID	Gene Info
Srf Ensembl NCBI MGI UniProt	ENSMUSG00000015605.5	serum response factor

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr17_46556498_46556886	Srf	517	0.635445	-0.69	1.3e-01	Click!
chr17_46555816_46556119	Srf	208	0.874547	-0.52	3.0e-01	Click!
chr17_46556258_46556418	Srf	163	0.905587	0.47	3.5e-01	Click!

Activity of the Srf motif across conditions

Conditions sorted by the z-value of the Srf motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_16830224_16830396	0.87	Egfros	epidermal growth factor receptor, opposite strand	392	0.88
chr3_69139928_69140109	0.80	Gm1647	predicted gene 1647	8785	0.14
chr7_44473035_44473343	0.74	5430431A17Rik	RIKEN cDNA 5430431A17 gene	349	0.67
chr2_72223053_72223218	0.74	Rapgef4os2	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 2	9167	0.17
chr15_7135984_7136307	0.73	Lifr	LIF receptor alpha	4397	0.32
chr13_59533414_59533566	0.73	Agtpbp1	ATP/GTP binding protein 1	300	0.88
chr1_184606698_184606874	0.72	Rpl21-ps1	ribosomal protein 21, pseudogene 1	10462	0.15
chr14_30254871_30255032	0.72	Gm47570	predicted gene, 47570	47213	0.13
chr14_20892049_20892245	0.71	Gm6128	predicted pseudogene 6128	35726	0.13
chr7_114290333_114290662	0.70	Psma1	proteasome subunit alpha 1	14379	0.21
chr16_45806302_45806490	0.69	Phldb2	pleckstrin homology like domain, family B, member 2	4825	0.22
chr4_137810112_137810287	0.68	Alpl	alkaline phosphatase, liver/bone/kidney	13815	0.19
chr5_120103213_120103364	0.67	Rbm19	RNA binding motif protein 19	13177	0.19
chr7_106644629_106644780	0.66	Olfr693	olfactory receptor 693	33781	0.1
chr8_41545072_41545241	0.65	Gapdh-ps14	glyceraldehyde-3-phosphate dehydrogenase, pseudogene 14	64513	0.13
chr2_118318601_118318758	0.64	1700054M17Rik	RIKEN cDNA 1700054M17 gene	13765	0.13
chr18_11851878_11852035	0.64	Cables1	CDK5 and Abl enzyme substrate 1	7656	0.17
chr7_77888814_77888965	0.58	Gm23239	predicted gene, 23239	21431	0.28
chr10_68248229_68248529	0.56	Arid5b	AT rich interactive domain 5B (MRF1-like)	30342	0.19
chr1_106200916_106201079	0.56	Gm38235	predicted gene, 38235	18317	0.17
chr12_85462932_85463085	0.55	Fos	FBJ osteosarcoma oncogene	10882	0.16
chrX_111648183_111648334	0.55	Hdx	highly divergent homeobox	48821	0.16
chr9_49514430_49514581	0.55	Gm11149	predicted gene 11149	3783	0.24
chr6_136930874_136931029	0.54	Pde6h	phosphodiesterase 6H, cGMP-specific, cone, gamma	7119	0.13
chr6_38949943_38950137	0.54	Tbxas1	thromboxane A synthase 1, platelet	8639	0.19
chr5_21139662_21139813	0.54	Gm42660	predicted gene 42660	8661	0.14
chr3_18146281_18146519	0.54	Gm23686	predicted gene, 23686	31225	0.18
chr12_110381296_110381622	0.53	Gm47195	predicted gene, 47195	56074	0.08
chr16_18187372_18187523	0.53	Mir6366	microRNA 6366	22277	0.08
chr2_122086820_122087004	0.52	Spg11	SPG11, spatacsin vesicle trafficking associated	31384	0.11
chr11_16851040_16851282	0.51	Egfros	epidermal growth factor receptor, opposite strand	20459	0.18
chr5_138255290_138255446	0.51	Lamtor4	late endosomal/lysosomal adaptor, MAPK and MTOR activator 4	114	0.89
chr5_113872987_113873184	0.51	Coro1c	coronin, actin binding protein 1C	1563	0.25
chr2_92380520_92380699	0.51	1700029I15Rik	RIKEN cDNA 1700029I15 gene	1929	0.18
chr10_80289084_80289235	0.51	Rps15	ribosomal protein S15	3294	0.08
chr2_31165165_31165344	0.50	Gpr107	G protein-coupled receptor 107	7013	0.14
chr11_74493309_74493480	0.49	Rap1gap2	RAP1 GTPase activating protein 2	29357	0.16
chr4_103933550_103933744	0.49	Gm12719	predicted gene 12719	5894	0.25
chr4_135286870_135287040	0.49	Gm12983	predicted gene 12983	3720	0.15
chr1_171263377_171263582	0.49	B4galt3	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3	6849	0.07
chr11_12411537_12411721	0.48	Cobl	cordon-bleu WH2 repeat	515	0.87
chr9_50595278_50595579	0.48	Sdhd	succinate dehydrogenase complex, subunit D, integral membrane protein	8384	0.1
chr16_10417919_10418097	0.48	Nubp1	nucleotide binding protein 1	3228	0.2
chr7_4815487_4815639	0.47	Ube2s	ubiquitin-conjugating enzyme E2S	2973	0.11
chr11_16826830_16827159	0.47	Egfros	epidermal growth factor receptor, opposite strand	3708	0.27
chr11_16871782_16871933	0.47	Egfr	epidermal growth factor receptor	6293	0.22
chr3_142439924_142440082	0.47	Pdlim5	PDZ and LIM domain 5	44307	0.13
chr11_16899277_16899448	0.46	Egfr	epidermal growth factor receptor	5823	0.21
chr15_58983651_58983950	0.46	4930544F09Rik	RIKEN cDNA 4930544F09 gene	336	0.87
chr18_15407944_15408276	0.45	Aqp4	aquaporin 4	22	0.98
chr15_7189723_7189941	0.44	Egflam	EGF-like, fibronectin type III and laminin G domains	33237	0.19
chr1_170997840_170997991	0.44	Gm10522	predicted gene 10522	15971	0.08
chr3_122120313_122120499	0.44	Abca4	ATP-binding cassette, sub-family A (ABC1), member 4	366	0.85
chrX_74244741_74244892	0.44	Flna	filamin, alpha	1548	0.18
chr4_63402725_63402887	0.44	Akna	AT-hook transcription factor	548	0.68
chr10_12821465_12821645	0.43	Utrn	utrophin	5383	0.21
chr1_15610696_15611021	0.43	Gm37138	predicted gene, 37138	54609	0.13
chr11_101060306_101060475	0.43	Naglu	alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)	9622	0.09
chr4_43558706_43558873	0.43	Tln1	talin 1	329	0.72
chr8_11272313_11272503	0.43	Col4a1	collagen, type IV, alpha 1	7248	0.18
chr4_55485084_55485235	0.43	Gm22150	predicted gene, 22150	16000	0.13
chr12_81188687_81188872	0.43	Mir3067	microRNA 3067	22628	0.18
chr11_98775529_98775744	0.42	Nr1d1	nuclear receptor subfamily 1, group D, member 1	303	0.81
chr8_121968047_121968241	0.42	Gm17709	predicted gene, 17709	5678	0.11
chr10_99154735_99154910	0.42	Poc1b	POC1 centriolar protein B	16462	0.12
chr16_95728927_95729113	0.42	Ets2	E26 avian leukemia oncogene 2, 3' domain	11286	0.18
chr3_138231897_138232387	0.42	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	4091	0.14
chr3_95985374_95985550	0.41	Plekho1	pleckstrin homology domain containing, family O member 1	10206	0.11
chr13_90896944_90897260	0.41	Atp6ap1l	ATPase, H+ transporting, lysosomal accessory protein 1-like	1722	0.38
chr2_18381810_18381961	0.41	Dnajc1	DnaJ heat shock protein family (Hsp40) member C1	10535	0.23
chr12_104346091_104346278	0.41	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	7698	0.12
chr15_55265818_55265991	0.41	Gm26296	predicted gene, 26296	3301	0.29
chr13_100543031_100543362	0.41	Ocln	occludin	9264	0.12
chr1_170607667_170608002	0.40	Nos1ap	nitric oxide synthase 1 (neuronal) adaptor protein	17973	0.17
chr9_14396183_14396345	0.40	Gm47319	predicted gene, 47319	10572	0.11
chr15_94676553_94676729	0.40	Gm25546	predicted gene, 25546	4745	0.27
chr4_119966810_119966961	0.39	Hivep3	human immunodeficiency virus type I enhancer binding protein 3	65881	0.12
chr1_155109783_155109942	0.39	Ier5	immediate early response 5	10226	0.15
chr6_71205289_71205700	0.39	Fabp1	fatty acid binding protein 1, liver	5667	0.13
chr14_22964972_22965155	0.39	Gm47601	predicted gene, 47601	37137	0.22
chr10_116220817_116221022	0.39	Ptprr	protein tyrosine phosphatase, receptor type, R	24523	0.18
chr11_114875733_114875884	0.39	Gprc5c	G protein-coupled receptor, family C, group 5, member C	11316	0.12
chr12_103658352_103658505	0.39	Serpina6	serine (or cysteine) peptidase inhibitor, clade A, member 6	1216	0.31
chr7_110539127_110539556	0.39	Gm10087	predicted gene 10087	12549	0.18
chr3_79565517_79565668	0.39	Fnip2	folliculin interacting protein 2	2087	0.19
chr13_45857382_45857567	0.39	Atxn1	ataxin 1	14814	0.25
chr14_31018658_31018887	0.39	Gnl3	guanine nucleotide binding protein-like 3 (nucleolar)	217	0.61
chr15_77842610_77842777	0.39	Myh9	myosin, heavy polypeptide 9, non-muscle	518	0.7
chr14_51883561_51883781	0.38	Mettl17	methyltransferase like 17	1171	0.27
chr10_23816629_23816780	0.38	Slc18b1	solute carrier family 18, subfamily B, member 1	7783	0.12
chr1_160036977_160037141	0.38	Gm37294	predicted gene, 37294	7272	0.17
chrX_136172356_136172537	0.38	Tceal8	transcription elongation factor A (SII)-like 8	104	0.94
chr10_99285837_99286030	0.37	Gm48089	predicted gene, 48089	11137	0.12
chr11_87749523_87749805	0.37	Mir142hg	Mir142 host gene (non-protein coding)	5913	0.09
chr14_20081120_20081302	0.37	Saysd1	SAYSVFN motif domain containing 1	1972	0.31
chr9_46215947_46216118	0.37	Sik3	SIK family kinase 3	3539	0.13
chr18_7620800_7620994	0.37	Mpp7	membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)	5920	0.24
chr3_127780482_127780684	0.37	Alpk1	alpha-kinase 1	56	0.96
chr1_33757706_33757887	0.37	Bag2	BCL2-associated athanogene 2	1	0.97
chr19_53554531_53554692	0.37	Gm50394	predicted gene, 50394	24956	0.11
chr12_86833864_86834026	0.37	Gm10095	predicted gene 10095	12522	0.19
chr17_80677489_80677679	0.36	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	26434	0.19
chr9_74894770_74895613	0.36	Onecut1	one cut domain, family member 1	28707	0.13
chr4_101490584_101490753	0.36	Dnajc6	DnaJ heat shock protein family (Hsp40) member C6	5963	0.21
chr5_143055727_143055894	0.36	Gm43378	predicted gene 43378	5767	0.15
chr18_5186924_5187075	0.36	Gm26682	predicted gene, 26682	21268	0.24
chr1_63178308_63178488	0.36	Gm26457	predicted gene, 26457	279	0.62
chr13_56648096_56648259	0.36	Tgfbi	transforming growth factor, beta induced	16964	0.19
chr6_142459631_142459782	0.36	Gys2	glycogen synthase 2	13403	0.16
chr12_35681929_35682122	0.35	9130015A21Rik	RIKEN cDNA 9130015A21 gene	4279	0.24
chr7_19131416_19131589	0.35	Fbxo46	F-box protein 46	191	0.86
chr9_66157716_66157867	0.35	Dapk2	death-associated protein kinase 2	432	0.83
chr5_129415440_129415591	0.35	Gm43001	predicted gene 43001	51395	0.13
chr13_4771823_4771989	0.35	Gm5444	predicted gene 5444	255	0.94
chr19_30246847_30246998	0.35	Mbl2	mannose-binding lectin (protein C) 2	13980	0.19
chr6_128662223_128662572	0.35	Clec2h	C-type lectin domain family 2, member h	6	0.89
chr3_56014019_56014179	0.35	Gm42840	predicted gene 42840	3069	0.25
chr11_16885540_16885691	0.35	Egfr	epidermal growth factor receptor	7465	0.21
chr13_28654991_28655297	0.35	Mir6368	microRNA 6368	55729	0.15
chr17_25082238_25082418	0.35	Tmem204	transmembrane protein 204	1138	0.34
chr6_90603208_90603366	0.35	Slc41a3	solute carrier family 41, member 3	1438	0.31
chr15_7194778_7194945	0.34	Egflam	EGF-like, fibronectin type III and laminin G domains	28208	0.2
chr10_18069023_18069192	0.34	Reps1	RalBP1 associated Eps domain containing protein	13103	0.19
chr9_107651281_107651577	0.34	Slc38a3	solute carrier family 38, member 3	4591	0.08
chr6_99364656_99364808	0.34	Gm20705	predicted gene 20705	23767	0.22
chr9_21167812_21167963	0.34	Pde4a	phosphodiesterase 4A, cAMP specific	2173	0.17
chr7_127819457_127819621	0.33	Stx4a	syntaxin 4A (placental)	4755	0.08
chr9_7959424_7959575	0.33	Yap1	yes-associated protein 1	6322	0.18
chr9_50492228_50492379	0.33	Plet1	placenta expressed transcript 1	2222	0.22
chr7_130518318_130518504	0.33	Ate1	arginyltransferase 1	1050	0.41
chr12_69517687_69517891	0.33	5830428M24Rik	RIKEN cDNA 5830428M24 gene	42239	0.1
chr11_51061072_51061284	0.33	Zfp354a	zinc finger protein 354A	1056	0.35
chr12_112720973_112721159	0.33	Cep170b	centrosomal protein 170B	611	0.56
chr9_95194235_95194412	0.33	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9	72637	0.11
chr2_37578235_37578422	0.33	Strbp	spermatid perinuclear RNA binding protein	8190	0.18
chr12_41084537_41084707	0.33	Immp2l	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	16310	0.21
chr15_12209919_12210084	0.32	Mtmr12	myotubularin related protein 12	4883	0.13
chr3_62349486_62349833	0.32	Arhgef26	Rho guanine nucleotide exchange factor (GEF) 26	8558	0.24
chr8_34951587_34951746	0.32	Gm9939	predicted gene 9939	13386	0.17
chr15_85042397_85042828	0.32	Fam118a	family with sequence similarity 118, member A	130	0.94
chrX_99292874_99293036	0.32	Gm14809	predicted gene 14809	125940	0.05
chr9_9104761_9104983	0.32	Gm16833	predicted gene, 16833	131416	0.05
chr17_30458453_30458632	0.32	Gm50250	predicted gene, 50250	8144	0.16
chr13_23556410_23556600	0.31	H1f3	H1.3 linker histone, cluster member	3243	0.06
chr14_22493467_22493618	0.31	4930405A10Rik	RIKEN cDNA 4930405A10 gene	49256	0.15
chr6_23098041_23098398	0.31	Aass	aminoadipate-semialdehyde synthase	29361	0.14
chr17_81006523_81006701	0.31	Thumpd2	THUMP domain containing 2	58455	0.12
chr8_111828693_111828997	0.31	Cfdp1	craniofacial development protein 1	25446	0.14
chr12_72482174_72482506	0.31	Lrrc9	leucine rich repeat containing 9	6266	0.2
chr13_41643806_41643994	0.31	Gm5082	predicted gene 5082	5543	0.21
chr11_106412539_106412732	0.31	Icam2	intercellular adhesion molecule 2	24560	0.13
chr1_92724078_92724229	0.31	Gm29483	predicted gene 29483	6951	0.15
chr3_119042748_119042912	0.31	Gm43410	predicted gene 43410	174586	0.03
chr19_4134482_4134777	0.31	Cabp4	calcium binding protein 4	4697	0.06
chr12_41345678_41346003	0.31	Gm47376	predicted gene, 47376	2250	0.28
chr2_58773576_58773851	0.31	Upp2	uridine phosphorylase 2	8388	0.21
chr13_28466271_28466432	0.31	2610307P16Rik	RIKEN cDNA 2610307P16 gene	14490	0.21
chr1_170006602_170006897	0.31	3110045C21Rik	RIKEN cDNA 3110045C21 gene	37297	0.13
chr2_83714821_83715007	0.31	Itgav	integrin alpha V	9483	0.16
chr1_130387327_130387514	0.31	Cd55b	CD55 molecule, decay accelerating factor for complement B	35320	0.11
chr11_16911020_16911171	0.31	Egfr	epidermal growth factor receptor	5910	0.2
chr7_89579648_89579808	0.30	Gm45064	predicted gene 45064	27362	0.13
chr3_121340564_121340760	0.30	Gm5711	predicted gene 5711	40017	0.11
chr4_95207881_95208040	0.30	Gm12708	predicted gene 12708	14598	0.2
chr3_129767244_129767395	0.30	Egf	epidermal growth factor	12003	0.12
chr14_66870804_66870955	0.30	Gm5464	predicted gene 5464	2029	0.24
chr7_141429982_141430161	0.30	Cend1	cell cycle exit and neuronal differentiation 1	580	0.43
chr15_66783892_66784052	0.30	Tg	thyroglobulin	14778	0.18
chr3_142569357_142569508	0.30	Gbp3	guanylate binding protein 3	8198	0.13
chr10_79838143_79838304	0.30	Misp	mitotic spindle positioning	8937	0.06
chr1_91104292_91104494	0.30	Lrrfip1	leucine rich repeat (in FLII) interacting protein 1	6821	0.19
chr7_27357399_27357576	0.30	Gm20479	predicted gene 20479	68	0.94
chr1_4544211_4544388	0.30	Gm38076	predicted gene, 38076	9013	0.13
chr2_53102207_53102377	0.30	Prpf40a	pre-mRNA processing factor 40A	43017	0.19
chr17_13441059_13441220	0.30	Rnu6	U6 small nuclear RNA	9000	0.12
chr13_98952126_98952306	0.30	Gm35215	predicted gene, 35215	6300	0.13
chr7_65737343_65737722	0.30	Tm2d3	TM2 domain containing 3	44008	0.12
chr10_41992198_41992354	0.30	Armc2	armadillo repeat containing 2	890	0.62
chr6_34722780_34722959	0.29	Npn2	neoplastic progression 2	4036	0.16
chr10_95408627_95408789	0.29	Socs2	suppressor of cytokine signaling 2	4026	0.16
chr16_35075564_35075912	0.29	Hacd2	3-hydroxyacyl-CoA dehydratase 2	27123	0.17
chr15_77816105_77816293	0.29	Myh9	myosin, heavy polypeptide 9, non-muscle	2968	0.2
chr17_13144924_13145092	0.29	Unc93a	unc-93 homolog A	13198	0.12
chr5_28079367_28079544	0.29	Insig1	insulin induced gene 1	4789	0.19
chr6_116653345_116653528	0.29	Depp1	DEPP1 autophagy regulator	2740	0.15
chr19_40478313_40478475	0.29	Sorbs1	sorbin and SH3 domain containing 1	9161	0.21
chr5_119877302_119877469	0.29	Gm43269	predicted gene 43269	37553	0.13
chr7_80044210_80044553	0.29	Gm44951	predicted gene 44951	7676	0.12
chr10_95254224_95254433	0.29	Gm48880	predicted gene, 48880	60525	0.08
chr4_86318074_86318389	0.29	Adamtsl1	ADAMTS-like 1	41465	0.19
chr6_31090797_31090948	0.29	Lncpint	long non-protein coding RNA, Trp53 induced transcript	2401	0.18
chr5_124232389_124232618	0.29	Pitpnm2os1	phosphatidylinositol transfer protein, membrane-associated 2, opposite strand 1	2778	0.16
chr11_83271635_83271942	0.29	Gm23444	predicted gene, 23444	290	0.8
chr10_61160789_61160964	0.29	Tbata	thymus, brain and testes associated	11078	0.15
chr6_122310324_122310479	0.29	M6pr	mannose-6-phosphate receptor, cation dependent	1402	0.29
chr12_108370797_108370948	0.29	Eml1	echinoderm microtubule associated protein like 1	85	0.97
chr7_127973702_127973919	0.29	Fus	fused in sarcoma	333	0.72
chr5_123382074_123382225	0.28	Mlxip	MLX interacting protein	12649	0.07
chr11_69667800_69667951	0.28	Gm24029	predicted gene, 24029	101	0.56
chr11_59994414_59994592	0.28	Pemt	phosphatidylethanolamine N-methyltransferase	10763	0.14

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Srf

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.6	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.1	0.6	GO:0038165	oncostatin-M-mediated signaling pathway(GO:0038165)
0.1	0.4	GO:0021593	rhombomere morphogenesis(GO:0021593)
0.1	0.5	GO:0070295	renal water absorption(GO:0070295)
0.1	0.4	GO:0072262	metanephric glomerular mesangium development(GO:0072223) metanephric glomerular mesangial cell proliferation involved in metanephros development(GO:0072262)
0.1	0.4	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.1	0.3	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.1	0.3	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.1	0.4	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1	0.4	GO:0048669	collateral sprouting in absence of injury(GO:0048669)
0.1	0.5	GO:0072711	response to hydroxyurea(GO:0072710) cellular response to hydroxyurea(GO:0072711)
0.1	0.2	GO:0071918	urea transmembrane transport(GO:0071918)
0.1	0.4	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.1	0.1	GO:0019371	cyclooxygenase pathway(GO:0019371)
0.1	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.4	GO:0035166	post-embryonic hemopoiesis(GO:0035166)
0.1	0.2	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.1	0.2	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.1	0.3	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.1	0.2	GO:0070537	histone H2A K63-linked deubiquitination(GO:0070537)
0.1	0.2	GO:0007525	somatic muscle development(GO:0007525)
0.1	0.2	GO:0009957	epidermal cell fate specification(GO:0009957)
0.1	0.2	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.2	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.2	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1	0.3	GO:0045918	negative regulation of cytolysis(GO:0045918)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.2	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.2	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.2	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.1	GO:0019042	viral latency(GO:0019042)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.2	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.0	0.2	GO:0060948	cardiac vascular smooth muscle cell development(GO:0060948)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.0	GO:1900238	cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.1	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.0	0.1	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.3	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.6	GO:1902895	positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0	0.2	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.0	GO:0070343	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.2	GO:0072307	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0071316	cellular response to nicotine(GO:0071316)
0.0	0.2	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.0	0.1	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.0	0.2	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.2	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.3	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.2	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.0	0.2	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.1	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.2	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.1	GO:0001805	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0	0.2	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0010912	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.0	GO:1904706	negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0	0.2	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.2	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.1	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.1	GO:0097212	lysosomal membrane organization(GO:0097212)
0.0	0.1	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.0	0.3	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.1	GO:0006600	creatine metabolic process(GO:0006600)
0.0	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.1	GO:0006808	regulation of nitrogen utilization(GO:0006808)
0.0	0.1	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.0	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
0.0	0.1	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.0	0.2	GO:0021796	cerebral cortex regionalization(GO:0021796)
0.0	0.1	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.0	0.1	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.0	GO:0002740	negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.0	0.1	GO:0043031	negative regulation of macrophage activation(GO:0043031)
0.0	0.1	GO:0071898	regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0	0.4	GO:0061462	protein localization to lysosome(GO:0061462)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.1	GO:0042231	interleukin-13 biosynthetic process(GO:0042231)
0.0	0.1	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.2	GO:0034375	high-density lipoprotein particle remodeling(GO:0034375)
0.0	0.1	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.2	GO:0061318	renal filtration cell differentiation(GO:0061318) glomerular epithelium development(GO:0072010) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0	0.1	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.0	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.1	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.1	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.0	GO:1902946	protein localization to early endosome(GO:1902946) regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.4	GO:0006968	cellular defense response(GO:0006968)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.2	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.2	GO:0018119	peptidyl-cysteine S-nitrosylation(GO:0018119)
0.0	0.1	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.2	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.1	GO:0072697	protein localization to cell cortex(GO:0072697)
0.0	0.0	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.1	GO:0060956	endocardial cell differentiation(GO:0060956)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0035290	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.0	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.0	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.1	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.1	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0035799	ureter maturation(GO:0035799)
0.0	0.1	GO:0002925	positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.0	0.1	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.1	GO:0010288	response to lead ion(GO:0010288)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.0	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.0	GO:0001831	trophectodermal cellular morphogenesis(GO:0001831)
0.0	0.1	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:0060666	dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0021530	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.1	GO:1903984	regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0	0.4	GO:0003298	physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.1	GO:1901341	positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.1	GO:0061370	testosterone biosynthetic process(GO:0061370)
0.0	0.1	GO:0072102	glomerulus morphogenesis(GO:0072102)
0.0	0.0	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0018904	ether metabolic process(GO:0018904)
0.0	0.1	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.0	GO:0030397	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.0	GO:0035608	protein deglutamylation(GO:0035608)
0.0	0.1	GO:0044332	Wnt signaling pathway involved in dorsal/ventral axis specification(GO:0044332)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.0	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.0	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:1902714	negative regulation of interferon-gamma secretion(GO:1902714)
0.0	0.1	GO:0010701	positive regulation of norepinephrine secretion(GO:0010701)
0.0	0.1	GO:0044351	macropinocytosis(GO:0044351)
0.0	0.0	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:0070317	negative regulation of G0 to G1 transition(GO:0070317)
0.0	0.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.2	GO:0044406	adhesion of symbiont to host(GO:0044406)
0.0	0.3	GO:0015813	L-glutamate transport(GO:0015813)
0.0	0.2	GO:0002862	negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0	0.1	GO:0097084	vascular smooth muscle cell development(GO:0097084)
0.0	0.1	GO:0030205	dermatan sulfate metabolic process(GO:0030205)
0.0	0.2	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.0	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
0.0	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0061299	retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.1	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.1	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.0	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.0	GO:0007161	calcium-independent cell-matrix adhesion(GO:0007161)
0.0	0.0	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0030049	muscle filament sliding(GO:0030049)
0.0	0.0	GO:0035483	gastric emptying(GO:0035483)
0.0	0.1	GO:0016540	protein autoprocessing(GO:0016540)
0.0	0.0	GO:1901033	positive regulation of response to reactive oxygen species(GO:1901033)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:0030150	protein import into mitochondrial matrix(GO:0030150)
0.0	0.1	GO:0090270	fibroblast growth factor production(GO:0090269) regulation of fibroblast growth factor production(GO:0090270)
0.0	0.0	GO:0007354	zygotic determination of anterior/posterior axis, embryo(GO:0007354)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.1	GO:0061732	mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0	0.0	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.0	GO:1905098	negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.0	0.1	GO:0016557	peroxisome membrane biogenesis(GO:0016557)
0.0	0.0	GO:0045541	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0015911	plasma membrane long-chain fatty acid transport(GO:0015911) fatty acid transmembrane transport(GO:1902001)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.0	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.2	GO:0007026	negative regulation of microtubule depolymerization(GO:0007026)
0.0	0.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.0	GO:1900060	negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.0	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) substrate-dependent cerebral cortex tangential migration(GO:0021825) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0	0.0	GO:0035188	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0	0.1	GO:0045793	positive regulation of cell size(GO:0045793)
0.0	0.0	GO:0090245	axis elongation involved in somitogenesis(GO:0090245)
0.0	0.1	GO:0061620	glycolytic process through glucose-6-phosphate(GO:0061620)
0.0	0.0	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.0	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.0	GO:0072513	positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0	0.0	GO:0000727	double-strand break repair via break-induced replication(GO:0000727)
0.0	0.1	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.1	GO:0006857	oligopeptide transport(GO:0006857)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.0	GO:0097067	cellular response to thyroid hormone stimulus(GO:0097067)
0.0	0.0	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.0	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.1	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.1	GO:0016139	glycoside catabolic process(GO:0016139)
0.0	0.0	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.0	GO:0034197	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.1	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.1	GO:0051085	chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0	0.1	GO:0030204	chondroitin sulfate metabolic process(GO:0030204)
0.0	0.0	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.0	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.0	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.1	GO:0010917	negative regulation of mitochondrial membrane potential(GO:0010917)
0.0	0.0	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.0	GO:0071404	cellular response to low-density lipoprotein particle stimulus(GO:0071404)
0.0	0.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.0	GO:0040031	snRNA modification(GO:0040031)
0.0	0.0	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.0	GO:1900147	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.1	GO:0050957	equilibrioception(GO:0050957)
0.0	0.1	GO:0035729	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	0.0	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0021873	forebrain neuroblast division(GO:0021873)
0.0	0.1	GO:0035337	fatty-acyl-CoA metabolic process(GO:0035337)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0097513	myosin II filament(GO:0097513)
0.1	0.6	GO:0044294	dendritic growth cone(GO:0044294)
0.1	0.5	GO:0071986	Ragulator complex(GO:0071986)
0.1	0.2	GO:0097451	glial limiting end-foot(GO:0097451)
0.1	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.3	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.4	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.2	GO:0045180	basal cortex(GO:0045180)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.3	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.2	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0030891	VCB complex(GO:0030891)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0070820	tertiary granule(GO:0070820)
0.0	0.0	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.4	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.0	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.3	GO:0046930	pore complex(GO:0046930)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0031527	filopodium membrane(GO:0031527)
0.0	0.2	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)
0.0	0.2	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.2	GO:0036038	MKS complex(GO:0036038)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0030056	hemidesmosome(GO:0030056)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0000805	X chromosome(GO:0000805)
0.0	0.1	GO:0000801	central element(GO:0000801)
0.0	0.0	GO:0072534	perineuronal net(GO:0072534)
0.0	0.1	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.0	GO:0044393	microspike(GO:0044393)
0.0	0.2	GO:0000800	lateral element(GO:0000800)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.0	GO:0005944	phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0034464	BBSome(GO:0034464)
0.0	0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.6	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.7	GO:0015288	porin activity(GO:0015288)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.2	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.2	GO:0015205	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.1	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.1	0.2	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.1	0.2	GO:0008158	hedgehog receptor activity(GO:0008158)
0.1	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.2	GO:0070538	oleic acid binding(GO:0070538)
0.1	0.3	GO:0030274	LIM domain binding(GO:0030274)
0.1	0.2	GO:0004046	aminoacylase activity(GO:0004046)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.0	GO:0035276	ethanol binding(GO:0035276)
0.0	0.3	GO:0043495	protein anchor(GO:0043495)
0.0	0.1	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.5	GO:1990841	promoter-specific chromatin binding(GO:1990841)
0.0	0.2	GO:0030957	Tat protein binding(GO:0030957)
0.0	0.1	GO:0015119	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0004365	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.6	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.2	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.3	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.3	GO:0034901	pinocarveol dehydrogenase activity(GO:0018446) chloral hydrate dehydrogenase activity(GO:0018447) hydroxymethylmethylsilanediol oxidase activity(GO:0018448) 1-phenylethanol dehydrogenase activity(GO:0018449) myrtenol dehydrogenase activity(GO:0018450) cis-1,2-dihydroxy-1,2-dihydro-8-carboxynaphthalene dehydrogenase activity(GO:0034522) 3-hydroxy-4-methyloctanoyl-CoA dehydrogenase activity(GO:0034582) 2-hydroxy-4-isopropenylcyclohexane-1-carboxyl-CoA dehydrogenase activity(GO:0034778) cis-9,10-dihydroanthracene-9,10-diol dehydrogenase activity(GO:0034817) citronellol dehydrogenase activity(GO:0034821) naphthyl-2-hydroxymethyl-succinyl-CoA dehydrogenase activity(GO:0034847) 2,4,4-trimethyl-1-pentanol dehydrogenase activity(GO:0034863) 2,4,4-trimethyl-3-hydroxypentanoyl-CoA dehydrogenase activity(GO:0034868) 1-hydroxy-4,4-dimethylpentan-3-one dehydrogenase activity(GO:0034871) endosulfan diol dehydrogenase activity(GO:0034891) endosulfan hydroxyether dehydrogenase activity(GO:0034901) 3-hydroxy-2-methylhexanoyl-CoA dehydrogenase activity(GO:0034918) 3-hydroxy-2,6-dimethyl-5-methylene-heptanoyl-CoA dehydrogenase activity(GO:0034944) versicolorin reductase activity(GO:0042469) ketoreductase activity(GO:0045703)
0.0	0.3	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.2	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.1	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.3	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.3	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0031750	D3 dopamine receptor binding(GO:0031750)
0.0	0.0	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.6	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.1	GO:0015198	oligopeptide transporter activity(GO:0015198)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.1	GO:0000104	succinate dehydrogenase activity(GO:0000104)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.1	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0	0.3	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0008401	retinoic acid 4-hydroxylase activity(GO:0008401)
0.0	0.5	GO:0071837	HMG box domain binding(GO:0071837)
0.0	0.1	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.1	GO:0016714	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.0	0.1	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:1990430	extracellular matrix protein binding(GO:1990430)
0.0	0.1	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.0	0.1	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.0	0.6	GO:0008536	Ran GTPase binding(GO:0008536)
0.0	0.4	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.0	GO:0008271	secondary active sulfate transmembrane transporter activity(GO:0008271)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.0	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.2	GO:0008307	structural constituent of muscle(GO:0008307)
0.0	0.2	GO:0015245	fatty acid transporter activity(GO:0015245)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.5	GO:0042805	actinin binding(GO:0042805)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.0	GO:0003747	translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0	0.1	GO:0018812	3-hydroxyacyl-CoA dehydratase activity(GO:0018812)
0.0	0.1	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0	0.2	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.0	GO:0019002	GMP binding(GO:0019002)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.0	GO:0005148	prolactin receptor binding(GO:0005148)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0001849	complement component C1q binding(GO:0001849)
0.0	0.2	GO:0001848	complement binding(GO:0001848)
0.0	0.1	GO:0019864	IgG binding(GO:0019864)
0.0	0.1	GO:0004438	phosphatidylinositol-3-phosphatase activity(GO:0004438)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.1	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.2	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.3	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.0	0.2	GO:0030275	LRR domain binding(GO:0030275)
0.0	0.4	GO:0050699	WW domain binding(GO:0050699)
0.0	0.0	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0	0.1	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.0	GO:0051373	FATZ binding(GO:0051373)
0.0	0.0	GO:0032190	acrosin binding(GO:0032190)
0.0	0.0	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0	0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	0.1	GO:0033743	peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0	0.2	GO:0004012	phospholipid-translocating ATPase activity(GO:0004012)
0.0	0.1	GO:0004016	adenylate cyclase activity(GO:0004016)
0.0	0.1	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.0	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.0	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.8	GO:0051087	chaperone binding(GO:0051087)
0.0	0.2	GO:0035255	ionotropic glutamate receptor binding(GO:0035255)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.0	GO:0034617	tetrahydrobiopterin binding(GO:0034617)
0.0	0.0	GO:0004663	Rab geranylgeranyltransferase activity(GO:0004663)
0.0	0.1	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.0	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.0	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.0	GO:0030229	very-low-density lipoprotein particle receptor activity(GO:0030229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	1.3	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.3	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.0	ST STAT3 PATHWAY	STAT3 Pathway
0.0	0.3	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	0.0	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.3	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.0	0.2	PID LPA4 PATHWAY	LPA4-mediated signaling events
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.3	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.2	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	0.2	PID S1P S1P3 PATHWAY	S1P3 pathway
0.0	0.1	NABA MATRISOME	Ensemble of genes encoding extracellular matrix and extracellular matrix-associated proteins
0.0	0.0	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID HIF1A PATHWAY	Hypoxic and oxygen homeostasis regulation of HIF-1-alpha

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.4	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	0.6	REACTOME PASSIVE TRANSPORT BY AQUAPORINS	Genes involved in Passive Transport by Aquaporins
0.0	0.8	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.4	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.0	0.2	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	0.1	REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP	Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0	0.2	REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA	Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0	0.6	REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT	Genes involved in ABC-family proteins mediated transport
0.0	0.1	REACTOME ERKS ARE INACTIVATED	Genes involved in ERKs are inactivated
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	0.2	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.3	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.1	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.3	REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE	Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0	0.2	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.0	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.5	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.3	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.6	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.1	REACTOME MAPK TARGETS NUCLEAR EVENTS MEDIATED BY MAP KINASES	Genes involved in MAPK targets/ Nuclear events mediated by MAP kinases
0.0	0.2	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.1	REACTOME AMYLOIDS	Genes involved in Amyloids
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.0	REACTOME SEMA3A PAK DEPENDENT AXON REPULSION	Genes involved in Sema3A PAK dependent Axon repulsion
0.0	0.1	REACTOME CS DS DEGRADATION	Genes involved in CS/DS degradation
0.0	0.1	REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB	Genes involved in PKA-mediated phosphorylation of CREB
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN	Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0	0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.1	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0	0.3	REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC	Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0	0.2	REACTOME GLYCOLYSIS	Genes involved in Glycolysis

Results for Srf

Z-value: 2.15

Motif logo

Transcription factors associated with Srf

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Srf motif across conditions

Conditions sorted by the z-value of the Srf motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Srf

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: