Project

ENCSR904DTN: DNase-seq of mouse liver in constant darkness

Navigation

Downloads

Results for Stat2

Z-value: 1.53

Motif logo

Transcription factors associated with Stat2

Gene Symbol	Gene ID	Gene Info
Stat2 Ensembl NCBI MGI UniProt	ENSMUSG00000040033.9	signal transducer and activator of transcription 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_128284141_128284299	Stat2	113	0.900570	-0.93	6.3e-03	Click!
chr10_128270229_128270557	Stat2	166	0.855244	0.81	4.9e-02	Click!
chr10_128282999_128283173	Stat2	269	0.773730	0.78	6.9e-02	Click!
chr10_128269993_128270177	Stat2	474	0.544022	-0.58	2.3e-01	Click!
chr10_128283909_128284096	Stat2	105	0.905025	-0.54	2.7e-01	Click!

Activity of the Stat2 motif across conditions

Conditions sorted by the z-value of the Stat2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_143985180_143985331	1.31	Rgs2	regulator of G-protein signaling 2	18777	0.26
chr3_59228865_59229051	1.02	P2ry12	purinergic receptor P2Y, G-protein coupled 12	1377	0.34
chrX_140541717_140541904	0.97	Tsc22d3	TSC22 domain family, member 3	858	0.63
chr17_7884908_7885059	0.95	Tagap	T cell activation Rho GTPase activating protein	41017	0.13
chr14_103487043_103487238	0.94	Gm34907	predicted gene, 34907	23089	0.17
chr8_3270214_3270530	0.94	Insr	insulin receptor	9179	0.19
chr1_180293183_180293340	0.93	Psen2	presenilin 2	29823	0.11
chr17_5574750_5574911	0.93	Zdhhc14	zinc finger, DHHC domain containing 14	82273	0.08
chr6_31502787_31502943	0.83	Mkln1	muskelin 1, intracellular mediator containing kelch motifs	10244	0.19
chr6_125527760_125527927	0.81	Vwf	Von Willebrand factor	18931	0.15
chr1_186703631_186703811	0.79	Tgfb2	transforming growth factor, beta 2	612	0.62
chr11_118710151_118710384	0.75	Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	50774	0.14
chr5_103592755_103593053	0.75	Gm15844	predicted gene 15844	31567	0.12
chr13_113168060_113168232	0.74	Gzmk	granzyme K	12751	0.12
chr13_107616531_107616706	0.73	Gm32090	predicted gene, 32090	3769	0.28
chr16_85656359_85656645	0.73	Gm6278	predicted gene 6278	12250	0.26
chr9_42958548_42958708	0.71	Gm5831	predicted gene 5831	6244	0.18
chr8_105332685_105332845	0.70	Fhod1	formin homology 2 domain containing 1	1199	0.21
chr5_145993052_145993431	0.70	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	1598	0.28
chr17_12245181_12245338	0.69	Map3k4	mitogen-activated protein kinase kinase kinase 4	15043	0.14
chr1_189628086_189628247	0.69	Gm38122	predicted gene, 38122	12068	0.2
chr2_131089744_131089895	0.67	Siglec1	sialic acid binding Ig-like lectin 1, sialoadhesin	3054	0.15
chr9_32500974_32501128	0.67	Gm27201	predicted gene 27201	7362	0.12
chr13_41386761_41386912	0.66	Gm48571	predicted gene, 48571	6880	0.15
chr11_85571105_85571339	0.65	Bcas3	breast carcinoma amplified sequence 3	9820	0.25
chr4_135989135_135989286	0.65	Pithd1	PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1	1946	0.16
chr4_99942092_99942280	0.65	Itgb3bp	integrin beta 3 binding protein (beta3-endonexin)	12373	0.17
chr11_118265609_118265912	0.64	Usp36	ubiquitin specific peptidase 36	288	0.89
chr16_32171079_32171230	0.64	Nrros	negative regulator of reactive oxygen species	5560	0.13
chr1_173912982_173913178	0.64	Ifi211	interferon activated gene 211	34	0.97
chr10_99467357_99467534	0.64	Gm35035	predicted gene, 35035	7215	0.16
chr10_78087254_78087405	0.64	Icosl	icos ligand	13990	0.12
chr15_58016804_58016970	0.64	9130401M01Rik	RIKEN cDNA 9130401M01 gene	11008	0.14
chr12_108174892_108175202	0.63	Setd3	SET domain containing 3	4166	0.23
chr8_31149644_31149904	0.63	Snord13	small nucleolar RNA, C/D box 13	193	0.79
chr8_72409462_72409669	0.63	Eps15l1	epidermal growth factor receptor pathway substrate 15-like 1	11873	0.1
chr8_40892111_40892272	0.62	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	6247	0.17
chr12_3846090_3846255	0.61	Dnmt3a	DNA methyltransferase 3A	3463	0.22
chr19_40661223_40661381	0.61	Entpd1	ectonucleoside triphosphate diphosphohydrolase 1	809	0.55
chr9_114621205_114621361	0.61	Cnot10	CCR4-NOT transcription complex, subunit 10	18680	0.14
chr11_58959242_58959404	0.60	H3f4	H3.4 histone	2489	0.1
chr1_148903211_148903363	0.60	Gm4034	predicted gene 4034	35089	0.16
chr16_35919055_35919394	0.60	Gm10237	predicted gene 10237	1240	0.32
chr13_37638048_37638218	0.60	Gm40916	predicted gene, 40916	10103	0.12
chr17_86470447_86470748	0.60	Prkce	protein kinase C, epsilon	19965	0.22
chr11_60076243_60076400	0.59	Rai1	retinoic acid induced 1	28692	0.12
chr1_192106002_192106194	0.59	Rcor3	REST corepressor 3	2753	0.18
chr16_28851482_28851645	0.59	Mb21d2	Mab-21 domain containing 2	15196	0.27
chr11_48902108_48902274	0.58	Gm5431	predicted gene 5431	23	0.96
chr1_182670647_182670811	0.58	Gm37516	predicted gene, 37516	9210	0.19
chr16_38711344_38711500	0.57	Arhgap31	Rho GTPase activating protein 31	1476	0.34
chr9_78443149_78443365	0.57	Cgas	cyclic GMP-AMP synthase	20	0.95
chr16_32124485_32124636	0.57	Gm15729	predicted gene 15729	15695	0.1
chr13_37337352_37337507	0.57	Ly86	lymphocyte antigen 86	7779	0.17
chr2_3816168_3816319	0.57	Gm13180	predicted gene 13180	38787	0.13
chr7_71232911_71233088	0.57	6030442E23Rik	RIKEN cDNA 6030442E23 gene	15950	0.2
chr13_34667342_34667503	0.56	Gm47149	predicted gene, 47149	13499	0.12
chr12_85462932_85463085	0.56	Fos	FBJ osteosarcoma oncogene	10882	0.16
chr5_122702283_122702531	0.56	Gm10064	predicted gene 10064	4807	0.13
chr12_79633582_79633770	0.56	9430078K24Rik	RIKEN cDNA 9430078K24 gene	291057	0.01
chr17_26753562_26753741	0.55	Crebrf	CREB3 regulatory factor	4051	0.18
chr5_21131284_21131470	0.55	Gm42660	predicted gene 42660	301	0.86
chr15_77598689_77598840	0.55	Gm36245	predicted gene, 36245	494	0.65
chr11_48994173_48994324	0.55	Tgtp1	T cell specific GTPase 1	76	0.93
chr7_104400820_104400986	0.55	Trim30c	tripartite motif-containing 30C	66	0.94
chr15_3323137_3323569	0.55	Ccdc152	coiled-coil domain containing 152	19827	0.22
chr8_26697737_26697895	0.55	Gm32098	predicted gene, 32098	29510	0.14
chr12_86836691_86837004	0.54	Gm10095	predicted gene 10095	9620	0.19
chr4_156200761_156200940	0.54	Isg15	ISG15 ubiquitin-like modifier	54	0.94
chr10_91080633_91080784	0.54	Apaf1	apoptotic peptidase activating factor 1	1721	0.28
chr11_75636681_75636832	0.54	Inpp5k	inositol polyphosphate 5-phosphatase K	2381	0.18
chr13_100201790_100201966	0.54	Naip2	NLR family, apoptosis inhibitory protein 2	83	0.97
chr2_91216142_91216316	0.54	Acp2	acid phosphatase 2, lysosomal	13301	0.09
chr4_155069080_155069295	0.54	Pex10	peroxisomal biogenesis factor 10	2128	0.21
chr1_173766990_173767157	0.54	Ifi204	interferon activated gene 204	130	0.94
chr5_99669989_99670358	0.53	Gm16226	predicted gene 16226	12237	0.14
chr12_69513282_69513448	0.53	5830428M24Rik	RIKEN cDNA 5830428M24 gene	37815	0.11
chr2_84800465_84800712	0.53	Ube2l6	ubiquitin-conjugating enzyme E2L 6	1754	0.21
chr17_29431823_29432064	0.53	Gm36199	predicted gene, 36199	892	0.45
chr7_141010698_141010858	0.53	Ifitm3	interferon induced transmembrane protein 3	8	0.94
chr17_78249106_78249271	0.53	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	11416	0.18
chr1_173802690_173802855	0.53	Ifi203-ps	interferon activated gene 203, pseudogene	4502	0.15
chr8_26353598_26353766	0.52	Gm31784	predicted gene, 31784	41348	0.11
chr3_30421777_30421938	0.52	Gm37024	predicted gene, 37024	66569	0.09
chr14_16773016_16773167	0.52	Rarb	retinoic acid receptor, beta	45914	0.19
chr3_146122899_146123050	0.51	Mcoln3	mucolipin 3	1302	0.37
chr14_66872697_66872883	0.51	Gm5464	predicted gene 5464	3940	0.18
chr2_35327379_35327530	0.51	Stom	stomatin	6949	0.14
chr11_26413799_26413986	0.51	Gm12713	predicted gene 12713	4685	0.26
chr15_74960861_74961016	0.50	Ly6e	lymphocyte antigen 6 complex, locus E	4383	0.1
chr17_50025214_50025398	0.50	AC133946.1	oxidoreductase NAD-binding domain containing 1 (OXNAD1) pseudogene	52479	0.12
chr14_58321390_58321541	0.50	Gm33321	predicted gene, 33321	20483	0.25
chr4_130286644_130286809	0.50	Serinc2	serine incorporator 2	7521	0.15
chr14_59341330_59341500	0.50	Phf11b	PHD finger protein 11B	64	0.97
chr2_72114198_72114385	0.50	Rapgef4	Rap guanine nucleotide exchange factor (GEF) 4	26420	0.18
chr2_35496007_35496180	0.50	Gm13445	predicted gene 13445	4574	0.15
chr6_121226902_121227083	0.50	Gm15856	predicted gene 15856	839	0.5
chr1_156037427_156037588	0.50	Tor1aip1	torsin A interacting protein 1	1027	0.38
chr8_128481066_128481284	0.50	Nrp1	neuropilin 1	121778	0.05
chr5_72796402_72796578	0.50	Tec	tec protein tyrosine kinase	10470	0.15
chr14_17410906_17411057	0.49	Thrb	thyroid hormone receptor beta	249280	0.02
chr2_144182222_144182616	0.49	Gm5535	predicted gene 5535	3333	0.2
chr18_69693406_69693588	0.49	Tcf4	transcription factor 4	11117	0.29
chr7_81592748_81592914	0.49	Gm45698	predicted gene 45698	1937	0.2
chr15_81521072_81521223	0.49	Gm5218	predicted gene 5218	21602	0.11
chr17_75128732_75128883	0.49	Gm6276	predicted pseudogene 6276	36400	0.19
chr4_107285558_107285727	0.49	Gm12850	predicted gene 12850	15208	0.11
chr14_59260201_59260363	0.49	Phf11	PHD finger protein 11	102	0.97
chr16_13478810_13479017	0.48	Mir6365	microRNA 6365	7733	0.13
chr6_5165732_5165895	0.48	Pon1	paraoxonase 1	27950	0.16
chr4_3724826_3724987	0.48	Gm11805	predicted gene 11805	3880	0.2
chr2_39011390_39011550	0.48	Arpc5l	actin related protein 2/3 complex, subunit 5-like	1452	0.23
chr19_3369445_3369596	0.48	Cpt1a	carnitine palmitoyltransferase 1a, liver	3190	0.18
chr8_45255175_45255326	0.47	F11	coagulation factor XI	6781	0.18
chr1_36133710_36133886	0.47	Gm33280	predicted gene, 33280	1756	0.26
chr18_60843903_60844067	0.47	Tcof1	treacle ribosome biogenesis factor 1	4461	0.17
chr17_34218807_34218993	0.47	Gm15821	predicted gene 15821	4441	0.08
chr1_75660839_75661011	0.46	Gm5257	predicted gene 5257	24535	0.15
chr4_126019139_126019304	0.46	Csf3r	colony stimulating factor 3 receptor (granulocyte)	5329	0.17
chr13_111816768_111816935	0.46	Gm15327	predicted gene 15327	6383	0.15
chr13_14063374_14063726	0.46	Ggps1	geranylgeranyl diphosphate synthase 1	62	0.72
chr13_45266886_45267041	0.46	Gm34466	predicted gene, 34466	748	0.7
chr5_123143767_123143973	0.46	Setd1b	SET domain containing 1B	913	0.32
chr5_36726541_36726703	0.46	Gm43701	predicted gene 43701	21996	0.11
chr10_3696942_3697316	0.46	Plekhg1	pleckstrin homology domain containing, family G (with RhoGef domain) member 1	43235	0.18
chr2_30464118_30464278	0.46	Ier5l	immediate early response 5-like	10021	0.13
chr6_31544399_31544550	0.45	Podxl	podocalyxin-like	19507	0.17
chr17_13542368_13542519	0.45	Gm26375	predicted gene, 26375	8274	0.13
chr2_132169135_132169286	0.45	Slc23a2	solute carrier family 23 (nucleobase transporters), member 2	24102	0.14
chr13_80891408_80891698	0.45	Arrdc3	arrestin domain containing 3	1035	0.49
chr4_105703446_105703745	0.45	Gm12728	predicted gene 12728	86274	0.1
chr7_47035073_47035236	0.45	Gm45474	predicted gene 45474	15142	0.08
chr5_90466463_90467083	0.44	Alb	albumin	4073	0.18
chr10_44380584_44380805	0.44	Mir1929	microRNA 1929	21018	0.18
chr6_101367186_101367358	0.44	Pdzrn3	PDZ domain containing RING finger 3	10070	0.16
chr2_173218906_173219070	0.44	Zbp1	Z-DNA binding protein 1	65	0.97
chr6_83482588_83482747	0.44	Dguok	deoxyguanosine kinase	4343	0.14
chr4_118158547_118158710	0.44	Kdm4a	lysine (K)-specific demethylase 4A	3029	0.2
chr5_122541967_122542146	0.44	Ift81	intraflagellar transport 81	18785	0.1
chr1_85526452_85526618	0.44	AC147806.2	predicted 7592	67	0.59
chr1_42532991_42533155	0.44	Gm37047	predicted gene, 37047	41260	0.17
chr15_58019663_58019825	0.43	9130401M01Rik	RIKEN cDNA 9130401M01 gene	8151	0.14
chr14_77033457_77033630	0.43	Lacc1	laccase domain containing 1	2538	0.28
chr17_40806554_40806751	0.43	Crisp2	cysteine-rich secretory protein 2	351	0.84
chr18_32693876_32694200	0.43	Gm25826	predicted gene, 25826	71982	0.1
chr13_24947230_24947390	0.43	Gpld1	glycosylphosphatidylinositol specific phospholipase D1	4158	0.15
chr11_116103660_116103816	0.43	Trim47	tripartite motif-containing 47	3345	0.12
chr4_11147012_11147305	0.43	Gm11830	predicted gene 11830	2448	0.18
chr14_31376509_31376660	0.42	Capn7	calpain 7	11028	0.13
chr19_55702816_55702984	0.42	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	38920	0.21
chr4_7143814_7143981	0.42	Gm11804	predicted gene 11804	104383	0.08
chr7_104244343_104244526	0.42	Trim34a	tripartite motif-containing 34A	23	0.94
chr4_117839519_117839685	0.42	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	4164	0.13
chr5_28004230_28004416	0.42	Gm4865	predicted gene 4865	3017	0.23
chr10_20674107_20674323	0.42	Gm17230	predicted gene 17230	48580	0.14
chr17_10367046_10367367	0.42	1700110C19Rik	RIKEN cDNA 1700110C19 gene	42604	0.16
chr2_27349025_27349208	0.41	Vav2	vav 2 oncogene	4636	0.19
chr17_64643456_64643864	0.41	Man2a1	mannosidase 2, alpha 1	42924	0.17
chr10_83859718_83859918	0.41	Gm47247	predicted gene, 47247	42034	0.15
chr19_42118558_42118858	0.41	Pi4k2a	phosphatidylinositol 4-kinase type 2 alpha	4030	0.13
chr2_129380377_129380528	0.41	Spcs2-ps	signal peptidase complex subunit 2, pseudogene	1056	0.39
chr7_141455779_141455943	0.41	Pnpla2	patatin-like phospholipase domain containing 2	254	0.76
chr14_75164007_75164166	0.41	Lcp1	lymphocyte cytosolic protein 1	10861	0.15
chr3_69139928_69140109	0.41	Gm1647	predicted gene 1647	8785	0.14
chr2_62408745_62408928	0.40	Dpp4	dipeptidylpeptidase 4	3023	0.24
chr2_68434673_68434858	0.40	Stk39	serine/threonine kinase 39	37175	0.16
chr6_82764174_82764475	0.40	Gm17034	predicted gene 17034	42	0.97
chr17_45814047_45814231	0.40	Gm35692	predicted gene, 35692	8184	0.17
chr7_38189586_38189737	0.40	1600014C10Rik	RIKEN cDNA 1600014C10 gene	3390	0.17
chr7_104507805_104508013	0.40	Trim30d	tripartite motif-containing 30D	60	0.94
chr1_173491252_173491410	0.40	Ifi206	interferon activated gene 206	290	0.89
chr13_52236242_52236425	0.39	Gm48199	predicted gene, 48199	55922	0.15
chr1_85199424_85199611	0.39	AC123856.1	nuclear antigen Sp100 (Sp100) pseudogene	96	0.49
chr6_56765406_56765619	0.39	Avl9	AVL9 cell migration associated	24599	0.13
chr5_86118821_86118972	0.39	Stap1	signal transducing adaptor family member 1	32438	0.12
chr17_35213144_35213303	0.39	Gm16181	predicted gene 16181	7611	0.04
chr8_56233770_56234075	0.39	Hpgd	hydroxyprostaglandin dehydrogenase 15 (NAD)	60663	0.13
chr17_87379036_87379189	0.39	Ttc7	tetratricopeptide repeat domain 7	259	0.89
chr1_85649860_85650030	0.39	Sp100	nuclear antigen Sp100	43	0.91
chr1_131246528_131246696	0.38	Rassf5	Ras association (RalGDS/AF-6) domain family member 5	1354	0.31
chr3_28543721_28543903	0.38	Tnik	TRAF2 and NCK interacting kinase	5534	0.3
chr11_109331467_109331634	0.38	1700096J18Rik	RIKEN cDNA 1700096J18 gene	15289	0.14
chr2_150831134_150831285	0.38	Pygb	brain glycogen phosphorylase	2821	0.2
chr11_54091828_54092005	0.38	P4ha2	procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide	8179	0.16
chr5_111467762_111467931	0.38	Gm43119	predicted gene 43119	44257	0.13
chr5_120749804_120749992	0.38	Oas2	2'-5' oligoadenylate synthetase 2	45	0.95
chr8_104110853_104111054	0.37	Cdh5	cadherin 5	354	0.82
chr13_59509852_59510003	0.37	Agtpbp1	ATP/GTP binding protein 1	4227	0.2
chr9_14717790_14718063	0.37	Piwil4	piwi-like RNA-mediated gene silencing 4	547	0.6
chr11_21082776_21082975	0.37	Peli1	pellino 1	8416	0.2
chr1_85327350_85327504	0.37	Gm2619	predicted gene 2619	142	0.87
chr15_79892259_79892434	0.37	Apobec3	apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3	57	0.95
chr12_103434049_103434233	0.37	Ifi27	interferon, alpha-inducible protein 27	70	0.94
chr7_123123444_123123981	0.37	Tnrc6a	trinucleotide repeat containing 6a	173	0.96
chr16_33347206_33347363	0.37	1700007L15Rik	RIKEN cDNA 1700007L15 gene	33391	0.16
chr17_36042825_36042981	0.36	Gm6034	predicted gene 6034	58	0.61
chr10_116264669_116264820	0.36	Ptprb	protein tyrosine phosphatase, receptor type, B	10779	0.19
chr8_84974794_84975075	0.36	AC163703.1		1608	0.14
chr4_140770556_140770730	0.36	Padi4	peptidyl arginine deiminase, type IV	3593	0.16
chr14_55604001_55604177	0.36	Irf9	interferon regulatory factor 9	104	0.87

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat2

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.2	0.5	GO:0051795	positive regulation of catagen(GO:0051795)
0.1	0.4	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.1	0.3	GO:1900226	negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.1	0.5	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.1	0.3	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.1	0.3	GO:1904124	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1	0.5	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.3	GO:1900368	regulation of RNA interference(GO:1900368)
0.1	0.3	GO:0010528	regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1	1.5	GO:0035455	response to interferon-alpha(GO:0035455)
0.1	0.2	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.1	0.3	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.2	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.1	0.3	GO:1901552	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.2	GO:0070889	platelet alpha granule organization(GO:0070889)
0.1	0.6	GO:0070269	pyroptosis(GO:0070269)
0.1	0.3	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.1	0.4	GO:0018377	protein myristoylation(GO:0018377)
0.1	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.1	0.2	GO:0002756	MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1	0.2	GO:0010908	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1	0.3	GO:0006548	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.1	0.1	GO:0010847	regulation of chromatin assembly(GO:0010847)
0.1	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1	0.2	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.1	0.2	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.1	0.1	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.1	0.2	GO:0052041	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.1	0.2	GO:0007571	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1	0.2	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	0.1	GO:2001171	regulation of ATP biosynthetic process(GO:2001169) positive regulation of ATP biosynthetic process(GO:2001171)
0.0	0.1	GO:0097048	dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.2	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.2	GO:1900225	regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0	0.1	GO:0002741	positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0	0.3	GO:0085020	protein K6-linked ubiquitination(GO:0085020)
0.0	1.0	GO:0035456	response to interferon-beta(GO:0035456)
0.0	0.7	GO:0061462	protein localization to lysosome(GO:0061462)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.5	GO:0045351	type I interferon biosynthetic process(GO:0045351)
0.0	0.2	GO:0050689	negative regulation of defense response to virus by host(GO:0050689)
0.0	0.3	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.0	0.3	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.0	0.4	GO:0032607	interferon-alpha production(GO:0032607)
0.0	0.8	GO:0034340	response to type I interferon(GO:0034340)
0.0	0.3	GO:0060267	positive regulation of respiratory burst(GO:0060267)
0.0	0.1	GO:0002337	B-1a B cell differentiation(GO:0002337)
0.0	1.0	GO:0042832	defense response to protozoan(GO:0042832)
0.0	0.1	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.2	GO:0090206	negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0	0.1	GO:0039534	negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0	0.1	GO:0051025	negative regulation of immunoglobulin secretion(GO:0051025)
0.0	0.1	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.4	GO:0060252	positive regulation of glial cell proliferation(GO:0060252)
0.0	0.3	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.2	GO:0035590	purinergic nucleotide receptor signaling pathway(GO:0035590)
0.0	0.1	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.1	GO:0050883	musculoskeletal movement, spinal reflex action(GO:0050883)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.1	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0030423	targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0	0.2	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.1	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.1	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	0.1	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.2	GO:0071442	positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0	0.1	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.1	GO:0046061	dATP catabolic process(GO:0046061)
0.0	0.2	GO:2000258	negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.3	GO:0035428	hexose transmembrane transport(GO:0035428)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:1902837	amino acid import into cell(GO:1902837)
0.0	0.1	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0033030	negative regulation of neutrophil apoptotic process(GO:0033030)
0.0	0.4	GO:0035278	miRNA mediated inhibition of translation(GO:0035278)
0.0	0.1	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.0	0.2	GO:0046719	regulation by virus of viral protein levels in host cell(GO:0046719)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.1	GO:0045402	interleukin-4 biosynthetic process(GO:0042097) regulation of interleukin-4 biosynthetic process(GO:0045402)
0.0	0.0	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.1	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.0	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.1	GO:0002291	T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0	0.2	GO:0018026	peptidyl-lysine monomethylation(GO:0018026)
0.0	0.1	GO:0032672	interleukin-3 production(GO:0032632) regulation of interleukin-3 production(GO:0032672)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.2	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.1	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0002432	granuloma formation(GO:0002432)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.1	GO:0009212	dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.3	GO:0035810	positive regulation of urine volume(GO:0035810)
0.0	0.2	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:0072197	ureter morphogenesis(GO:0072197)
0.0	0.1	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.0	0.0	GO:0045080	positive regulation of chemokine biosynthetic process(GO:0045080)
0.0	0.1	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.1	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.1	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.1	GO:1902202	regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0	0.2	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.1	GO:0045048	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.2	GO:0042983	amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)
0.0	0.4	GO:0043046	DNA methylation involved in gamete generation(GO:0043046)
0.0	0.3	GO:2000251	positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0	0.0	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.0	GO:0002339	B cell selection(GO:0002339)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.0	GO:0060375	regulation of mast cell differentiation(GO:0060375)
0.0	0.1	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0	0.0	GO:0002536	respiratory burst involved in inflammatory response(GO:0002536)
0.0	0.1	GO:1903054	negative regulation of extracellular matrix organization(GO:1903054)
0.0	0.1	GO:0072540	T-helper 17 cell lineage commitment(GO:0072540)
0.0	0.1	GO:0043928	exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0	0.2	GO:0009437	carnitine metabolic process(GO:0009437)
0.0	0.0	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.1	GO:0034145	positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.0	0.2	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.1	GO:1904222	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:1904754	positive regulation of vascular associated smooth muscle cell migration(GO:1904754)
0.0	0.1	GO:0044539	long-chain fatty acid import(GO:0044539)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.2	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.2	GO:0050957	equilibrioception(GO:0050957)
0.0	0.0	GO:0018171	peptidyl-cysteine oxidation(GO:0018171)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.0	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0031665	negative regulation of lipopolysaccharide-mediated signaling pathway(GO:0031665)
0.0	0.2	GO:0051152	positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0	0.0	GO:2000564	regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.1	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.1	GO:0090435	protein localization to nuclear envelope(GO:0090435)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.1	GO:0042939	glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0	0.1	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.2	GO:0006336	DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0	0.0	GO:0046101	hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0	0.0	GO:1901656	glycoside transport(GO:1901656)
0.0	0.0	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.0	0.1	GO:0002677	negative regulation of chronic inflammatory response(GO:0002677)
0.0	0.1	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	0.1	GO:0008594	photoreceptor cell morphogenesis(GO:0008594)
0.0	0.1	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.1	GO:0002457	T cell antigen processing and presentation(GO:0002457)
0.0	0.1	GO:0070234	positive regulation of T cell apoptotic process(GO:0070234)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0007220	Notch receptor processing(GO:0007220)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0046485	ether lipid metabolic process(GO:0046485)
0.0	0.1	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.2	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.0	GO:0070640	vitamin D3 metabolic process(GO:0070640)
0.0	0.0	GO:1904752	vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752)
0.0	0.0	GO:0002584	negative regulation of antigen processing and presentation of peptide antigen(GO:0002584)
0.0	0.1	GO:0034393	positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.0	0.0	GO:0060018	astrocyte fate commitment(GO:0060018)
0.0	0.0	GO:0060282	positive regulation of oocyte development(GO:0060282)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.0	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.0	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.0	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.3	GO:0034260	negative regulation of GTPase activity(GO:0034260)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.3	GO:0006879	cellular iron ion homeostasis(GO:0006879)
0.0	0.0	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.0	GO:1904339	negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0	0.1	GO:0042511	positive regulation of tyrosine phosphorylation of Stat1 protein(GO:0042511)
0.0	0.1	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.1	GO:0021779	oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.0	GO:1900044	regulation of protein K63-linked ubiquitination(GO:1900044)
0.0	0.0	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.0	0.0	GO:0045900	negative regulation of translational elongation(GO:0045900)
0.0	0.0	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.3	GO:0042088	T-helper 1 type immune response(GO:0042088)
0.0	0.0	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.0	0.2	GO:0042104	positive regulation of activated T cell proliferation(GO:0042104)
0.0	0.1	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.0	0.0	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.1	GO:0021756	striatum development(GO:0021756)
0.0	0.1	GO:0045162	clustering of voltage-gated sodium channels(GO:0045162)
0.0	0.0	GO:0090151	protein import into mitochondrial inner membrane(GO:0045039) establishment of protein localization to mitochondrial membrane(GO:0090151)
0.0	0.1	GO:0033216	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.1	GO:0046501	protoporphyrinogen IX metabolic process(GO:0046501)
0.0	0.1	GO:0007194	negative regulation of adenylate cyclase activity(GO:0007194)
0.0	0.0	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.0	0.1	GO:0002084	protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0	0.1	GO:0033132	negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0	0.2	GO:0015986	energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0	0.0	GO:0045054	constitutive secretory pathway(GO:0045054)
0.0	0.0	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.1	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0	0.0	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.1	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.3	GO:0008299	isoprenoid biosynthetic process(GO:0008299)
0.0	0.0	GO:0060480	lung goblet cell differentiation(GO:0060480)
0.0	0.0	GO:0045578	negative regulation of B cell differentiation(GO:0045578)
0.0	0.0	GO:2001025	positive regulation of response to drug(GO:2001025)
0.0	0.2	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0002669	positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0	0.0	GO:0032513	negative regulation of protein phosphatase type 2B activity(GO:0032513)
0.0	0.1	GO:0007614	short-term memory(GO:0007614)
0.0	0.0	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.0	0.0	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.1	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.0	GO:0043369	CD4-positive or CD8-positive, alpha-beta T cell lineage commitment(GO:0043369)
0.0	0.1	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0	0.0	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.0	0.1	GO:2000042	negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0	0.0	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.0	GO:0014735	regulation of muscle atrophy(GO:0014735)
0.0	0.1	GO:0005513	detection of calcium ion(GO:0005513)
0.0	0.1	GO:0016558	protein import into peroxisome matrix(GO:0016558)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:0045409	negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.0	0.0	GO:1990086	lens fiber cell apoptotic process(GO:1990086)
0.0	0.1	GO:0031584	activation of phospholipase D activity(GO:0031584)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.1	GO:0014049	positive regulation of glutamate secretion(GO:0014049)
0.0	0.0	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:0030157	pancreatic juice secretion(GO:0030157)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:0051712	positive regulation of killing of cells of other organism(GO:0051712)
0.0	0.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.3	GO:1903146	regulation of mitophagy(GO:1903146)
0.0	0.1	GO:0048702	embryonic neurocranium morphogenesis(GO:0048702)
0.0	0.0	GO:0043313	regulation of neutrophil degranulation(GO:0043313)
0.0	0.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.2	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0009838	abscission(GO:0009838)
0.0	0.0	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.0	GO:0065001	specification of axis polarity(GO:0065001)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.0	GO:2001270	regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.0	0.0	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.0	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.0	GO:0031446	regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0	0.0	GO:0015838	amino-acid betaine transport(GO:0015838)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0072557	IPAF inflammasome complex(GO:0072557)
0.1	0.3	GO:0044530	supraspliceosomal complex(GO:0044530)
0.1	0.2	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.2	GO:0043293	apoptosome(GO:0043293)
0.0	0.2	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0009279	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.3	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.2	GO:0071547	piP-body(GO:0071547)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.4	GO:0020003	symbiont-containing vacuole(GO:0020003)
0.0	0.1	GO:0043511	inhibin complex(GO:0043511)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.2	GO:0070531	BRCA1-A complex(GO:0070531)
0.0	0.2	GO:0033093	Weibel-Palade body(GO:0033093)
0.0	0.4	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.2	GO:1990462	omegasome(GO:1990462)
0.0	0.2	GO:0036056	filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0	0.2	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.2	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.1	GO:0035355	Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.0	0.1	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.0	GO:1990761	growth cone lamellipodium(GO:1990761)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.2	GO:0045179	apical cortex(GO:0045179)
0.0	0.1	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0035838	growing cell tip(GO:0035838)
0.0	0.1	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.2	GO:0097539	ciliary transition fiber(GO:0097539)
0.0	0.0	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0061689	tricellular tight junction(GO:0061689)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.2	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0044214	spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0	0.1	GO:0000938	GARP complex(GO:0000938)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0071437	invadopodium(GO:0071437)
0.0	0.2	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.0	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.3	GO:0030673	axolemma(GO:0030673)
0.0	0.0	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0019815	B cell receptor complex(GO:0019815)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0033116	endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0	0.1	GO:0016600	flotillin complex(GO:0016600)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.1	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.0	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	0.0	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0005863	striated muscle myosin thick filament(GO:0005863)
0.0	0.0	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0030663	COPI-coated vesicle membrane(GO:0030663)
0.0	0.1	GO:0030991	intraciliary transport particle A(GO:0030991)
0.0	0.0	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0031231	intrinsic component of peroxisomal membrane(GO:0031231)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.1	GO:0031430	M band(GO:0031430)
0.0	0.2	GO:0005605	basal lamina(GO:0005605)
0.0	0.1	GO:0031362	anchored component of external side of plasma membrane(GO:0031362)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.8	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1	0.5	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.1	0.3	GO:0008412	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.1	0.3	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.4	GO:0043262	adenosine-diphosphatase activity(GO:0043262)
0.1	0.4	GO:0052717	N-cyclopropylmelamine deaminase activity(GO:0034547) N-cyclopropylammeline deaminase activity(GO:0034548) N-cyclopropylammelide alkylamino hydrolase activity(GO:0034549) 2,5-diamino-6-ribitylamino-4(3H)-pyrimidinone 5'-phosphate deaminase activity(GO:0043723) tRNA-specific adenosine-37 deaminase activity(GO:0043829) archaeal-specific GTP cyclohydrolase activity(GO:0044682) tRNA-specific adenosine-34 deaminase activity(GO:0052717)
0.1	0.5	GO:0043426	MRF binding(GO:0043426)
0.1	0.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	0.2	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.1	0.5	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	0.2	GO:0003945	N-acetyllactosamine synthase activity(GO:0003945)
0.1	0.2	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.2	GO:0034584	piRNA binding(GO:0034584)
0.1	0.2	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.1	0.2	GO:0004060	arylamine N-acetyltransferase activity(GO:0004060)
0.1	0.3	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.1	0.3	GO:0016936	galactoside binding(GO:0016936)
0.0	0.4	GO:0031386	protein tag(GO:0031386)
0.0	0.6	GO:0045028	G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0	0.1	GO:0031697	beta-1 adrenergic receptor binding(GO:0031697)
0.0	0.2	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.4	GO:0001730	2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0	0.4	GO:0005283	sodium:amino acid symporter activity(GO:0005283)
0.0	0.1	GO:0070699	type II activin receptor binding(GO:0070699)
0.0	0.2	GO:0034190	apolipoprotein receptor binding(GO:0034190)
0.0	0.5	GO:0005521	lamin binding(GO:0005521)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0034040	lipid-transporting ATPase activity(GO:0034040)
0.0	0.1	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
0.0	0.1	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.2	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.2	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.1	GO:0052658	inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0	0.2	GO:0018638	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0003886	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0004614	phosphoglucomutase activity(GO:0004614)
0.0	0.2	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.1	GO:0023029	MHC class Ib protein binding(GO:0023029)
0.0	0.1	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.2	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.2	GO:0048019	receptor antagonist activity(GO:0048019)
0.0	0.1	GO:0016833	oxo-acid-lyase activity(GO:0016833)
0.0	0.2	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0008545	JUN kinase kinase activity(GO:0008545)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.4	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.2	GO:0043140	ATP-dependent 3'-5' DNA helicase activity(GO:0043140)
0.0	0.3	GO:0016505	peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.3	GO:0038187	signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0	0.2	GO:0035381	extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.3	GO:0046703	natural killer cell lectin-like receptor binding(GO:0046703)
0.0	0.1	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.4	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0016262	protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0	0.0	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.3	GO:0005351	sugar:proton symporter activity(GO:0005351)
0.0	0.1	GO:0004994	somatostatin receptor activity(GO:0004994)
0.0	0.4	GO:0070412	R-SMAD binding(GO:0070412)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.3	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.2	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.2	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.0	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0070840	dynein complex binding(GO:0070840)
0.0	0.1	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0035651	AP-3 adaptor complex binding(GO:0035651)
0.0	0.1	GO:0001224	RNA polymerase II transcription cofactor binding(GO:0001224)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.1	GO:0072542	protein phosphatase activator activity(GO:0072542)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.0	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.2	GO:0070628	proteasome binding(GO:0070628)
0.0	0.2	GO:0030159	receptor signaling complex scaffold activity(GO:0030159)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.6	GO:0048487	beta-tubulin binding(GO:0048487)
0.0	0.0	GO:0031752	D5 dopamine receptor binding(GO:0031752)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.1	GO:0016722	oxidoreductase activity, oxidizing metal ions(GO:0016722) oxidoreductase activity, oxidizing metal ions, NAD or NADP as acceptor(GO:0016723)
0.0	0.2	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0008157	protein phosphatase 1 binding(GO:0008157)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.1	GO:0015226	amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0	0.2	GO:0070016	armadillo repeat domain binding(GO:0070016)
0.0	0.0	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.1	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.0	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.1	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.0	GO:0004966	galanin receptor activity(GO:0004966)
0.0	0.1	GO:0098599	palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0	0.1	GO:0070034	telomerase RNA binding(GO:0070034)
0.0	0.1	GO:0042500	aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.0	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.0	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.0	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.0	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.1	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	1.2	GO:0001078	transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0	0.1	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.0	GO:0051033	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.2	GO:0015301	anion:anion antiporter activity(GO:0015301)
0.0	0.1	GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0	0.1	GO:0046961	hydrogen-exporting ATPase activity(GO:0036442) proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0	0.0	GO:1990459	transferrin receptor binding(GO:1990459)
0.0	0.1	GO:0008429	phosphatidylethanolamine binding(GO:0008429)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID TCR CALCIUM PATHWAY	Calcium signaling in the CD4+ TCR pathway
0.1	0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	0.4	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway
0.0	0.5	SA MMP CYTOKINE CONNECTION	Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0	0.6	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.2	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	0.0	PID PI3KCI AKT PATHWAY	Class I PI3K signaling events mediated by Akt
0.0	0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.0	0.0	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.0	0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.0	0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.0	0.3	PID S1P S1P2 PATHWAY	S1P2 pathway
0.0	0.5	SIG PIP3 SIGNALING IN B LYMPHOCYTES	Genes related to PIP3 signaling in B lymphocytes
0.0	0.3	PID INSULIN GLUCOSE PATHWAY	Insulin-mediated glucose transport
0.0	0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.3	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.3	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.0	PID GLYPICAN 1PATHWAY	Glypican 1 network
0.0	0.2	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.5	PID FCER1 PATHWAY	Fc-epsilon receptor I signaling in mast cells
0.0	0.0	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.3	PID RAS PATHWAY	Regulation of Ras family activation
0.0	0.0	PID IL12 2PATHWAY	IL12-mediated signaling events
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	3.5	REACTOME INTERFERON ALPHA BETA SIGNALING	Genes involved in Interferon alpha/beta signaling
0.0	0.5	REACTOME P2Y RECEPTORS	Genes involved in P2Y receptors
0.0	0.1	REACTOME ENDOSOMAL VACUOLAR PATHWAY	Genes involved in Endosomal/Vacuolar pathway
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.0	0.5	REACTOME INTRINSIC PATHWAY	Genes involved in Intrinsic Pathway
0.0	0.5	REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI	Genes involved in RIP-mediated NFkB activation via DAI
0.0	0.1	REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1	Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.6	REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING	Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.3	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.0	0.5	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.0	0.1	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1	Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0	0.0	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.1	REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the early endosome membrane
0.0	0.1	REACTOME ELONGATION ARREST AND RECOVERY	Genes involved in Elongation arrest and recovery
0.0	0.4	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.0	0.3	REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY	Genes involved in Post-chaperonin tubulin folding pathway
0.0	0.1	REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS	Genes involved in NRIF signals cell death from the nucleus
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.1	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.0	0.1	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.1	REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES	Genes involved in p75NTR recruits signalling complexes
0.0	0.3	REACTOME CHOLESTEROL BIOSYNTHESIS	Genes involved in Cholesterol biosynthesis
0.0	0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.1	REACTOME EGFR DOWNREGULATION	Genes involved in EGFR downregulation
0.0	0.2	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.4	REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION	Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.1	REACTOME BETA DEFENSINS	Genes involved in Beta defensins
0.0	0.2	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.3	REACTOME REGULATORY RNA PATHWAYS	Genes involved in Regulatory RNA pathways
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.0	0.8	REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2	Genes involved in Response to elevated platelet cytosolic Ca2+
0.0	0.3	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.3	REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING	Genes involved in Integrin alphaIIb beta3 signaling
0.0	0.1	REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING	Genes involved in Advanced glycosylation endproduct receptor signaling
0.0	0.3	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.0	REACTOME RAP1 SIGNALLING	Genes involved in Rap1 signalling
0.0	0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.0	0.1	REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS	Genes involved in Activation of the AP-1 family of transcription factors
0.0	0.2	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.0	0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	0.1	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.0	0.0	REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION	Genes involved in Cyclin E associated events during G1/S transition

Results for Stat2

Z-value: 1.53

Motif logo

Transcription factors associated with Stat2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Stat2 motif across conditions

Conditions sorted by the z-value of the Stat2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Stat2

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: