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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for T

Z-value: 1.54

Motif logo

Transcription factors associated with T

Gene Symbol	Gene ID	Gene Info
T Ensembl NCBI MGI UniProt	ENSMUSG00000062327.4	T

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
T	chr17_8468794_8468964	33468	0.136628	0.87	2.3e-02	Click!
T	chr17_8463571_8463745	28247	0.147138	0.80	5.4e-02	Click!

Activity of the T motif across conditions

Conditions sorted by the z-value of the T motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr12_104085193_104085357	1.62	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	4626	0.11
chr7_98352590_98353259	1.15	Tsku	tsukushi, small leucine rich proteoglycan	7155	0.18
chr2_58771100_58771251	1.00	Upp2	uridine phosphorylase 2	5850	0.22
chr9_106231818_106232229	0.93	Alas1	aminolevulinic acid synthase 1	5061	0.11
chr15_34500771_34501210	0.92	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	5667	0.12
chr6_72125643_72125794	0.83	4933431G14Rik	RIKEN cDNA 4933431G14 gene	2521	0.19
chr5_125526040_125526191	0.83	Tmem132b	transmembrane protein 132B	5659	0.17
chr8_70761775_70761926	0.78	Mpv17l2	MPV17 mitochondrial membrane protein-like 2	904	0.29
chr19_55549970_55550134	0.74	Vti1a	vesicle transport through interaction with t-SNAREs 1A	169038	0.03
chr3_131610645_131610810	0.73	Gm42881	predicted gene 42881	3053	0.32
chr10_81414192_81414360	0.73	Mir1191b	microRNA 1191b	2021	0.11
chr14_61680870_61681697	0.73	Gm37472	predicted gene, 37472	211	0.83
chr6_94083257_94083610	0.72	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	169743	0.03
chr7_67648192_67648343	0.69	Ttc23	tetratricopeptide repeat domain 23	807	0.52
chr2_31517780_31518546	0.69	Ass1	argininosuccinate synthetase 1	327	0.88
chr1_179587103_179587284	0.68	Cnst	consortin, connexin sorting protein	6197	0.2
chr11_16831950_16832169	0.68	Egfros	epidermal growth factor receptor, opposite strand	1357	0.48
chr14_18232288_18232439	0.67	Nr1d2	nuclear receptor subfamily 1, group D, member 2	6648	0.15
chr19_59940486_59940637	0.67	Rab11fip2	RAB11 family interacting protein 2 (class I)	2439	0.27
chr2_15065750_15065923	0.66	Arl5b	ADP-ribosylation factor-like 5B	2303	0.23
chr18_79032313_79032478	0.65	Setbp1	SET binding protein 1	76996	0.12
chr9_57680637_57680986	0.65	Cyp1a2	cytochrome P450, family 1, subfamily a, polypeptide 2	1225	0.34
chr14_21148896_21149047	0.64	Adk	adenosine kinase	72819	0.1
chr15_84115082_84115482	0.64	Pnpla5	patatin-like phospholipase domain containing 5	7893	0.11
chr11_100975850_100976001	0.63	Cavin1	caveolae associated 1	5038	0.14
chr13_58389633_58389784	0.63	Mir7-1	microRNA 7-1	3178	0.14
chr1_91460257_91460423	0.63	Per2	period circadian clock 2	1016	0.39
chr1_51741438_51741641	0.62	Gm28055	predicted gene 28055	5404	0.23
chr8_36378677_36378838	0.61	Gm5787	predicted gene 5787	5124	0.22
chr2_163301297_163301733	0.61	Tox2	TOX high mobility group box family member 2	18863	0.19
chr11_16836874_16837160	0.61	Egfros	epidermal growth factor receptor, opposite strand	6315	0.23
chr8_46502516_46502667	0.60	Acsl1	acyl-CoA synthetase long-chain family member 1	9759	0.16
chr1_161240339_161240617	0.60	Prdx6	peroxiredoxin 6	10076	0.16
chr3_89147086_89147561	0.60	Hcn3	hyperpolarization-activated, cyclic nucleotide-gated K+ 3	3891	0.08
chr11_28694681_28694832	0.60	2810471M01Rik	RIKEN cDNA 2810471M01 gene	13192	0.17
chr3_116520495_116520697	0.60	Dbt	dihydrolipoamide branched chain transacylase E2	268	0.83
chr19_44380608_44380766	0.59	Scd1	stearoyl-Coenzyme A desaturase 1	26003	0.12
chr11_11930894_11931056	0.59	Grb10	growth factor receptor bound protein 10	7641	0.19
chr9_74790782_74790933	0.59	Gm22315	predicted gene, 22315	8787	0.19
chr17_79999311_79999483	0.58	Gm41625	predicted gene, 41625	17735	0.14
chr11_43900248_43900399	0.58	Adra1b	adrenergic receptor, alpha 1b	887	0.69
chr11_6187368_6187519	0.58	Gm11969	predicted gene 11969	4409	0.13
chr5_66067953_66068113	0.57	Gm43775	predicted gene 43775	4862	0.14
chr1_88108297_88108598	0.57	Ugt1a6b	UDP glucuronosyltransferase 1 family, polypeptide A6B	1585	0.15
chr18_39366595_39366746	0.55	Arhgap26	Rho GTPase activating protein 26	4087	0.22
chr4_104891992_104892200	0.55	C8a	complement component 8, alpha polypeptide	15698	0.18
chr13_52771924_52772129	0.55	BB123696	expressed sequence BB123696	14821	0.27
chr8_36291164_36291366	0.55	Lonrf1	LON peptidase N-terminal domain and ring finger 1	41749	0.14
chr4_120805342_120805549	0.55	Nfyc	nuclear transcription factor-Y gamma	10267	0.12
chr14_46277334_46277485	0.54	Gm15217	predicted gene 15217	102005	0.06
chr5_101853831_101853982	0.54	Wdfy3	WD repeat and FYVE domain containing 3	2393	0.26
chr1_21245441_21245592	0.54	Gsta3	glutathione S-transferase, alpha 3	4887	0.13
chr3_18141090_18141285	0.53	Gm23686	predicted gene, 23686	36438	0.17
chr1_10155656_10155807	0.53	Arfgef1	ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)	1201	0.46
chr1_162860098_162860465	0.53	Fmo1	flavin containing monooxygenase 1	312	0.89
chr1_131548025_131548226	0.53	Fam72a	family with sequence similarity 72, member A	20222	0.13
chr9_9150893_9151066	0.52	Gm16833	predicted gene, 16833	85309	0.09
chr9_35125828_35126176	0.51	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	6734	0.13
chr19_44408067_44408294	0.51	Scd1	stearoyl-Coenzyme A desaturase 1	301	0.87
chr2_53063355_53063523	0.50	Prpf40a	pre-mRNA processing factor 40A	81870	0.1
chr1_162966553_162966755	0.50	Gm37273	predicted gene, 37273	16360	0.15
chr4_118427849_118428470	0.50	Elovl1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1	15	0.95
chr2_149243256_149243407	0.49	Gm14135	predicted gene 14135	13946	0.25
chr7_113913919_113914070	0.49	Spon1	spondin 1, (f-spondin) extracellular matrix protein	147820	0.04
chr5_24931562_24931772	0.49	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	22690	0.15
chr17_28513130_28513307	0.49	Fkbp5	FK506 binding protein 5	1861	0.15
chr15_76090888_76091336	0.49	Nrbp2	nuclear receptor binding protein 2	266	0.79
chr7_63922331_63923024	0.47	Klf13	Kruppel-like factor 13	2193	0.22
chr4_95659044_95659217	0.47	Fggy	FGGY carbohydrate kinase domain containing	22243	0.23
chr13_113023428_113023726	0.47	Cdc20b	cell division cycle 20B	11534	0.08
chr13_34709231_34709382	0.46	Gm47150	predicted gene, 47150	2143	0.2
chr1_182594265_182594416	0.46	Capn8	calpain 8	29302	0.15
chr13_31477017_31477445	0.46	Gm23351	predicted gene, 23351	49976	0.1
chr12_103936876_103937064	0.46	Gm17198	predicted gene 17198	10679	0.1
chr5_90460287_90460447	0.46	Alb	albumin	530	0.74
chr9_20869353_20869677	0.46	Shfl	shiftless antiviral inhibitor of ribosomal frameshifting	238	0.82
chr7_144604819_144604981	0.46	Ano1	anoctamin 1, calcium activated chloride channel	3395	0.21
chr1_92902865_92903036	0.45	Ankmy1	ankyrin repeat and MYND domain containing 1	44	0.95
chr14_120368762_120368913	0.45	Mbnl2	muscleblind like splicing factor 2	10404	0.23
chr15_81341905_81342180	0.45	Slc25a17	solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17	2115	0.25
chr15_97005714_97005879	0.44	Slc38a4	solute carrier family 38, member 4	14155	0.26
chr4_106938365_106938529	0.44	Ssbp3	single-stranded DNA binding protein 3	3251	0.27
chr12_105728790_105728966	0.44	Ak7	adenylate kinase 7	10022	0.17
chr1_51865962_51866337	0.44	Gm28323	predicted gene 28323	13459	0.15
chr6_52606460_52606970	0.44	Gm44434	predicted gene, 44434	3470	0.19
chr15_58701012_58701185	0.44	Fer1l6	fer-1-like 6 (C. elegans)	52593	0.13
chr14_63265088_63265239	0.44	Gata4	GATA binding protein 4	5961	0.19
chr19_44386173_44386338	0.44	Scd1	stearoyl-Coenzyme A desaturase 1	20435	0.13
chr4_46530716_46530867	0.44	Trim14	tripartite motif-containing 14	3623	0.16
chr12_91846364_91846572	0.44	Sel1l	sel-1 suppressor of lin-12-like (C. elegans)	2661	0.22
chr11_16832564_16832715	0.43	Egfros	epidermal growth factor receptor, opposite strand	1937	0.37
chr13_52819486_52819637	0.43	BB123696	expressed sequence BB123696	62356	0.13
chr14_21160817_21160968	0.43	Adk	adenosine kinase	84740	0.09
chr9_82972585_82972892	0.42	Phip	pleckstrin homology domain interacting protein	1530	0.44
chr9_48972648_48972807	0.42	Htr3b	5-hydroxytryptamine (serotonin) receptor 3B	7737	0.17
chr11_86581982_86582182	0.42	Mir21a	microRNA 21a	2076	0.25
chr6_117060427_117060748	0.42	Gm43929	predicted gene, 43929	78568	0.08
chr19_44415624_44415803	0.42	Gm50337	predicted gene, 50337	3897	0.17
chr2_119166975_119167320	0.42	Gchfr	GTP cyclohydrolase I feedback regulator	626	0.55
chr1_67207008_67207510	0.41	Gm15668	predicted gene 15668	41941	0.15
chr1_67187795_67187968	0.41	Gm15668	predicted gene 15668	61319	0.11
chr2_117250087_117250471	0.41	Fam98b	family with sequence similarity 98, member B	540	0.71
chr13_44285946_44286097	0.41	Gm29676	predicted gene, 29676	5572	0.22
chr19_26059257_26059433	0.41	1700048O14Rik	RIKEN cDNA 1700048O14 gene	12878	0.29
chr6_149333094_149333245	0.41	Resf1	retroelement silencing factor 1	7711	0.14
chr7_136457949_136458342	0.41	Gm36849	predicted gene, 36849	104781	0.07
chr1_63112731_63113827	0.41	Ino80dos	INO80 complex subunit D, opposite strand	201	0.84
chr15_25610986_25611308	0.41	Myo10	myosin X	11378	0.18
chr1_191720413_191720955	0.41	Lpgat1	lysophosphatidylglycerol acyltransferase 1	2163	0.28
chr13_63293999_63294179	0.41	Aopep	aminopeptidase O	4704	0.09
chr17_3243997_3244206	0.40	Gm49797	predicted gene, 49797	12830	0.17
chr11_119947790_119948239	0.40	Baiap2	brain-specific angiogenesis inhibitor 1-associated protein 2	4542	0.13
chr1_80244319_80244685	0.40	Gm37932	predicted gene, 37932	11695	0.13
chr15_36500919_36501077	0.40	Gm49246	predicted gene, 49246	2433	0.22
chr15_62114324_62114498	0.40	Pvt1	Pvt1 oncogene	15382	0.27
chr5_125517529_125517705	0.40	Aacs	acetoacetyl-CoA synthetase	2374	0.24
chr15_59044505_59044656	0.40	Mtss1	MTSS I-BAR domain containing 1	3983	0.26
chr1_33265899_33266050	0.40	Gm25792	predicted gene, 25792	27702	0.14
chr16_88252138_88252296	0.40	Grik1	glutamate receptor, ionotropic, kainate 1	37514	0.19
chr6_149144748_149145030	0.40	Etfbkmt	electron transfer flavoprotein beta subunit lysine methyltransferase	3243	0.17
chr13_63290686_63291046	0.40	Aopep	aminopeptidase O	7927	0.08
chr3_60111256_60111413	0.40	Gm24382	predicted gene, 24382	16413	0.19
chr11_100362773_100362924	0.39	Gm10039	predicted pseudogene 10039	722	0.42
chr2_155055757_155055908	0.39	a	nonagouti	8217	0.14
chr10_87869244_87869395	0.39	Igf1os	insulin-like growth factor 1, opposite strand	5938	0.21
chr2_65118329_65118522	0.39	Cobll1	Cobl-like 1	12566	0.26
chr1_33095638_33095817	0.39	Gm7114	predicted gene 7114	5180	0.19
chr16_43359282_43359433	0.39	Zbtb20	zinc finger and BTB domain containing 20	3691	0.21
chr12_35075187_35075338	0.39	Snx13	sorting nexin 13	10731	0.2
chr3_138222370_138222521	0.39	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	974	0.44
chr14_118948462_118948868	0.39	Dnajc3	DnaJ heat shock protein family (Hsp40) member C3	10689	0.16
chr1_51751151_51751308	0.39	Gm28055	predicted gene 28055	4286	0.24
chr14_47086994_47087145	0.39	Samd4	sterile alpha motif domain containing 4	66	0.96
chr6_144709361_144709513	0.39	Sox5os4	SRY (sex determining region Y)-box 5, opposite strand 4	11474	0.16
chr14_69499525_69499676	0.39	Gm37094	predicted gene, 37094	790	0.43
chr19_40998476_40998675	0.38	Blnk	B cell linker	4040	0.24
chr13_34322306_34322457	0.38	Gm47086	predicted gene, 47086	3573	0.23
chr10_77441826_77442020	0.38	Gm35920	predicted gene, 35920	15994	0.15
chr19_40138748_40138899	0.38	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	48463	0.1
chr1_182500736_182501185	0.38	Gm37069	predicted gene, 37069	6804	0.14
chr1_39545677_39545839	0.38	Snord89	small nucleolar RNA, C/D box 89	3096	0.14
chr1_127899100_127899290	0.38	Rab3gap1	RAB3 GTPase activating protein subunit 1	1718	0.35
chr6_51635883_51636035	0.38	Gm22914	predicted gene, 22914	14327	0.23
chr14_21181534_21181685	0.38	Adk	adenosine kinase	105457	0.06
chr2_38825025_38825397	0.38	Nr6a1os	nuclear receptor subfamily 6, group A, member 1, opposite strand	1870	0.21
chr7_13288728_13288901	0.38	Lig1	ligase I, DNA, ATP-dependent	8668	0.11
chr1_130734318_130734676	0.38	AA986860	expressed sequence AA986860	2387	0.14
chr2_27710029_27710632	0.37	Rxra	retinoid X receptor alpha	253	0.95
chr13_69532134_69532307	0.37	Tent4a	terminal nucleotidyltransferase 4A	212	0.89
chr5_43146388_43146587	0.37	Gm42552	predicted gene 42552	1840	0.38
chr2_148037591_148038164	0.37	9030622O22Rik	RIKEN cDNA 9030622O22 gene	393	0.84
chr14_69281268_69281419	0.37	Gm20236	predicted gene, 20236	797	0.41
chr3_122591417_122591662	0.37	Gm42994	predicted gene 42994	14467	0.12
chr11_120808277_120808502	0.37	Fasn	fatty acid synthase	216	0.85
chr1_51891769_51891920	0.37	Myo1b	myosin IB	4457	0.17
chr11_120806039_120806735	0.37	Fasn	fatty acid synthase	2218	0.14
chr2_180695831_180695982	0.37	Gm22502	predicted gene, 22502	2157	0.2
chr1_21242608_21242925	0.37	Gsta3	glutathione S-transferase, alpha 3	2137	0.2
chr10_87901489_87901918	0.37	Igf1os	insulin-like growth factor 1, opposite strand	38322	0.14
chr2_153427016_153427191	0.37	Gm14472	predicted gene 14472	13254	0.15
chr2_31506444_31506729	0.37	Ass1	argininosuccinate synthetase 1	5860	0.19
chr5_135732561_135732712	0.36	Por	P450 (cytochrome) oxidoreductase	545	0.61
chr3_138233542_138233745	0.36	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	5592	0.13
chr11_82871115_82871420	0.36	Rffl	ring finger and FYVE like domain containing protein	57	0.95
chr8_105087916_105088199	0.36	Ces3b	carboxylesterase 3B	562	0.61
chr11_59211030_59211307	0.36	Gm10434	predicted gene 10434	2448	0.13
chr16_85704612_85704964	0.36	Gm6278	predicted gene 6278	60536	0.13
chr17_65594339_65595183	0.36	Vapa	vesicle-associated membrane protein, associated protein A	209	0.93
chr1_140173562_140173824	0.36	Cfh	complement component factor h	9587	0.24
chr19_34313239_34313423	0.36	Fas	Fas (TNF receptor superfamily member 6)	13256	0.17
chr14_31635979_31636159	0.36	Gm49387	predicted gene, 49387	4809	0.15
chr15_34501373_34501524	0.36	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	6125	0.12
chr18_56460492_56460658	0.36	Gramd3	GRAM domain containing 3	8692	0.19
chr11_98563759_98564290	0.35	Zpbp2	zona pellucida binding protein 2	8581	0.11
chr15_34501595_34501764	0.35	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	6356	0.12
chr6_55384309_55384460	0.35	Ghrhr	growth hormone releasing hormone receptor	8019	0.17
chr5_123013925_123014136	0.35	Orai1	ORAI calcium release-activated calcium modulator 1	1044	0.22
chr4_97885703_97886090	0.35	Nfia	nuclear factor I/A	5777	0.31
chr14_66660010_66660243	0.35	Adra1a	adrenergic receptor, alpha 1a	24570	0.21
chr15_77115568_77115750	0.35	4833412C15Rik	RIKEN cDNA 4833412C15 gene	143	0.94
chr4_154429405_154429556	0.35	Prdm16	PR domain containing 16	81023	0.08
chr11_16830831_16831057	0.35	Egfros	epidermal growth factor receptor, opposite strand	242	0.94
chr5_76253852_76254003	0.35	Clock	circadian locomotor output cycles kaput	20085	0.12
chr8_105084813_105085337	0.35	Ces3b	carboxylesterase 3B	1312	0.28
chr5_121337098_121337279	0.35	Hectd4	HECT domain E3 ubiquitin protein ligase 4	17165	0.11
chr6_72098587_72098738	0.35	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	905	0.44
chr17_65865136_65865307	0.35	Ralbp1	ralA binding protein 1	2609	0.2
chr2_134494626_134494815	0.35	Hao1	hydroxyacid oxidase 1, liver	59587	0.16
chr4_154780999_154781159	0.35	Ttc34	tetratricopeptide repeat domain 34	56380	0.1
chr2_27727538_27727823	0.34	Rxra	retinoid X receptor alpha	2461	0.38
chr16_52349922_52350241	0.34	Alcam	activated leukocyte cell adhesion molecule	53157	0.18
chr15_81355699_81355864	0.34	Slc25a17	solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17	4946	0.16
chr16_87640129_87640300	0.34	Gm22808	predicted gene, 22808	19094	0.18
chr5_33466079_33466243	0.34	Gm43851	predicted gene 43851	28697	0.15
chr7_73608284_73608633	0.34	Gm44734	predicted gene 44734	490	0.68
chr4_80919570_80919748	0.34	Lurap1l	leucine rich adaptor protein 1-like	9013	0.26
chr17_83844829_83845052	0.34	Haao	3-hydroxyanthranilate 3,4-dioxygenase	1809	0.31
chr15_3463467_3463618	0.34	Ghr	growth hormone receptor	8102	0.29
chr6_28749445_28749607	0.34	Snd1	staphylococcal nuclease and tudor domain containing 1	15164	0.21
chr19_36362135_36362318	0.34	Gm47773	predicted gene, 47773	883	0.51

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of T

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.1	GO:0010046	response to mycotoxin(GO:0010046)
0.2	0.9	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.2	0.5	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1	0.6	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1	0.4	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.5	GO:0001907	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.1	0.5	GO:0003099	positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1	0.3	GO:2001271	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	1.1	GO:0009404	toxin metabolic process(GO:0009404)
0.1	0.3	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1	0.3	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.1	0.3	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.1	0.3	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.2	GO:0060741	prostate gland stromal morphogenesis(GO:0060741)
0.1	0.5	GO:0021960	anterior commissure morphogenesis(GO:0021960)
0.1	0.2	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.1	0.2	GO:1901162	serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1	0.1	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1	0.3	GO:0072338	creatinine metabolic process(GO:0046449) cellular lactam metabolic process(GO:0072338)
0.1	0.2	GO:0042126	nitrate metabolic process(GO:0042126)
0.1	0.4	GO:0009202	deoxyribonucleoside triphosphate biosynthetic process(GO:0009202)
0.1	0.3	GO:0090155	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156)
0.1	0.1	GO:1904504	regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.1	0.3	GO:0044789	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.3	GO:0015867	ATP transport(GO:0015867)
0.1	0.3	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.3	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.2	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1	0.4	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1	0.2	GO:0097167	circadian regulation of translation(GO:0097167)
0.1	0.2	GO:0006741	NADP biosynthetic process(GO:0006741)
0.1	0.2	GO:0019660	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.1	0.5	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.2	GO:0035973	aggrephagy(GO:0035973)
0.1	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1	0.2	GO:0061668	mitochondrial ribosome assembly(GO:0061668)
0.1	0.2	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1	0.2	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.2	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.2	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0000430	regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0	0.1	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.0	0.4	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.1	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.4	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.2	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.2	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.2	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0038026	reelin-mediated signaling pathway(GO:0038026)
0.0	0.1	GO:0032741	positive regulation of interleukin-18 production(GO:0032741)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.4	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.3	GO:0045714	regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.1	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.1	GO:0006659	phosphatidylserine biosynthetic process(GO:0006659)
0.0	0.2	GO:0046512	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.6	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:1903333	negative regulation of protein folding(GO:1903333)
0.0	0.2	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.1	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.1	GO:0032058	positive regulation of translational initiation in response to stress(GO:0032058)
0.0	0.1	GO:0035459	cargo loading into vesicle(GO:0035459)
0.0	0.1	GO:0051582	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0	0.1	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.2	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.2	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:2000074	regulation of type B pancreatic cell development(GO:2000074)
0.0	0.2	GO:0060440	trachea formation(GO:0060440)
0.0	0.1	GO:0018125	peptidyl-cysteine methylation(GO:0018125)
0.0	0.2	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.2	GO:1900227	positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0	0.2	GO:0060665	regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0	0.1	GO:0032898	neurotrophin production(GO:0032898)
0.0	0.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.1	GO:0042998	positive regulation of Golgi to plasma membrane protein transport(GO:0042998)
0.0	0.1	GO:1905065	positive regulation of vascular smooth muscle cell differentiation(GO:1905065)
0.0	0.1	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0075525	viral translational termination-reinitiation(GO:0075525)
0.0	0.2	GO:0045647	negative regulation of erythrocyte differentiation(GO:0045647)
0.0	0.2	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.1	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.0	0.1	GO:0061511	centriole elongation(GO:0061511)
0.0	0.1	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.0	0.1	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0	0.1	GO:0014063	negative regulation of serotonin secretion(GO:0014063)
0.0	0.2	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0070127	tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0	0.2	GO:0032509	endosome transport via multivesicular body sorting pathway(GO:0032509)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.3	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.1	GO:0098795	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.2	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0042424	catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.0	0.1	GO:0015766	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.1	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.0	0.1	GO:2000097	regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0	0.1	GO:0006573	valine metabolic process(GO:0006573)
0.0	0.1	GO:1903298	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0	0.2	GO:0060896	neural plate pattern specification(GO:0060896)
0.0	0.1	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.2	GO:0015677	copper ion import(GO:0015677)
0.0	0.1	GO:0090370	negative regulation of cholesterol efflux(GO:0090370)
0.0	0.1	GO:0010989	negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.1	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.0	GO:0045713	low-density lipoprotein particle receptor biosynthetic process(GO:0045713)
0.0	0.1	GO:0035754	B cell chemotaxis(GO:0035754)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.2	GO:0019321	pentose metabolic process(GO:0019321)
0.0	0.1	GO:1900016	negative regulation of cytokine production involved in inflammatory response(GO:1900016)
0.0	0.2	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.0	GO:1903207	neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0	0.0	GO:0060737	prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.2	GO:0070365	hepatocyte differentiation(GO:0070365)
0.0	0.1	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.3	GO:0045116	protein neddylation(GO:0045116)
0.0	0.0	GO:0071680	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:0014043	negative regulation of neuron maturation(GO:0014043)
0.0	0.1	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.0	GO:0007290	spermatid nucleus elongation(GO:0007290)
0.0	0.1	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.0	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.0	GO:1900242	regulation of synaptic vesicle endocytosis(GO:1900242)
0.0	0.2	GO:0010838	positive regulation of keratinocyte proliferation(GO:0010838)
0.0	0.1	GO:0003241	growth involved in heart morphogenesis(GO:0003241)
0.0	0.1	GO:2000270	negative regulation of fibroblast apoptotic process(GO:2000270)
0.0	0.3	GO:1990403	embryonic brain development(GO:1990403)
0.0	0.1	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.1	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.1	GO:0032229	negative regulation of synaptic transmission, GABAergic(GO:0032229)
0.0	0.0	GO:1990144	intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0	0.0	GO:1902966	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.0	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.1	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.1	GO:0018344	protein geranylgeranylation(GO:0018344)
0.0	0.1	GO:0033567	DNA replication, Okazaki fragment processing(GO:0033567)
0.0	0.2	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.1	GO:1903071	positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0	0.0	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.1	GO:0007035	vacuolar acidification(GO:0007035)
0.0	0.2	GO:0034723	DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0	0.0	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0051036	regulation of endosome size(GO:0051036)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.1	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.0	GO:2000211	regulation of glutamate metabolic process(GO:2000211)
0.0	0.0	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0008354	germ cell migration(GO:0008354)
0.0	0.1	GO:0060742	epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.2	GO:0045721	negative regulation of gluconeogenesis(GO:0045721)
0.0	0.1	GO:1902036	regulation of hematopoietic stem cell differentiation(GO:1902036)
0.0	0.0	GO:0051599	response to hydrostatic pressure(GO:0051599)
0.0	0.1	GO:0035814	negative regulation of renal sodium excretion(GO:0035814)
0.0	0.1	GO:0060689	cell differentiation involved in salivary gland development(GO:0060689)
0.0	0.1	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.2	GO:0010801	negative regulation of peptidyl-threonine phosphorylation(GO:0010801)
0.0	0.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	0.0	GO:0034436	glycoprotein transport(GO:0034436)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.1	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:1900113	regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.1	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.1	GO:2001197	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0010891	negative regulation of sequestering of triglyceride(GO:0010891)
0.0	0.0	GO:2000286	receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.0	0.0	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0070862	negative regulation of protein exit from endoplasmic reticulum(GO:0070862) regulation of retrograde protein transport, ER to cytosol(GO:1904152) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0	0.1	GO:0061051	positive regulation of cell growth involved in cardiac muscle cell development(GO:0061051)
0.0	0.0	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.0	GO:0042525	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.0	GO:0046005	positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0	0.1	GO:0060126	somatotropin secreting cell differentiation(GO:0060126)
0.0	0.0	GO:0006083	acetate metabolic process(GO:0006083)
0.0	0.1	GO:0060768	regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768)
0.0	0.1	GO:1902715	positive regulation of interferon-gamma secretion(GO:1902715)
0.0	0.0	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:1903358	regulation of Golgi organization(GO:1903358)
0.0	0.0	GO:0051446	positive regulation of meiotic cell cycle(GO:0051446)
0.0	0.0	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.1	GO:0090400	stress-induced premature senescence(GO:0090400)
0.0	0.0	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.0	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.0	GO:0071866	regulation of apoptotic process in bone marrow(GO:0071865) negative regulation of apoptotic process in bone marrow(GO:0071866)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.2	GO:0045948	positive regulation of translational initiation(GO:0045948)
0.0	0.0	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.1	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.0	0.1	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631)
0.0	0.2	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.0	GO:0007621	negative regulation of female receptivity(GO:0007621)
0.0	0.1	GO:0006568	tryptophan metabolic process(GO:0006568) indolalkylamine metabolic process(GO:0006586)
0.0	0.0	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.0	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.0	GO:0060279	positive regulation of ovulation(GO:0060279)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0008343	adult feeding behavior(GO:0008343)
0.0	0.0	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.0	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.0	GO:0016095	polyprenol catabolic process(GO:0016095)
0.0	0.0	GO:2000807	regulation of synaptic vesicle clustering(GO:2000807)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.0	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.0	GO:0010745	negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0086042	cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.0	0.1	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.0	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:0000188	inactivation of MAPK activity(GO:0000188)
0.0	0.1	GO:0055059	asymmetric neuroblast division(GO:0055059) asymmetric stem cell division(GO:0098722)
0.0	0.0	GO:2000599	regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0045842	positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.1	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.0	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.0	GO:0046341	CDP-diacylglycerol metabolic process(GO:0046341)
0.0	0.3	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0	0.0	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.0	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.1	GO:0048318	axial mesoderm development(GO:0048318)
0.0	0.0	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.1	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.1	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.0	0.0	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.0	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.1	GO:0071257	cellular response to electrical stimulus(GO:0071257)
0.0	0.1	GO:0060158	phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0	0.0	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.0	0.1	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.0	GO:0006069	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:1902857	positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0	0.0	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0	0.0	GO:0043366	beta selection(GO:0043366)
0.0	0.0	GO:0000467	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.1	GO:1900115	sequestering of extracellular ligand from receptor(GO:0035581) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.0	GO:0002426	immunoglobulin production in mucosal tissue(GO:0002426)
0.0	0.1	GO:0051461	positive regulation of corticotropin secretion(GO:0051461)
0.0	0.0	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.2	GO:0048026	positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.1	GO:0032736	positive regulation of interleukin-13 production(GO:0032736)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:1901984	negative regulation of protein acetylation(GO:1901984)
0.0	0.0	GO:1902661	regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.0	0.0	GO:0031585	regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031585)
0.0	0.0	GO:1901874	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.6	GO:0006888	ER to Golgi vesicle-mediated transport(GO:0006888)
0.0	0.1	GO:0006268	DNA unwinding involved in DNA replication(GO:0006268)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.0	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.3	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.2	GO:0006376	mRNA splice site selection(GO:0006376)
0.0	0.0	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.0	GO:0035751	regulation of lysosomal lumen pH(GO:0035751)
0.0	0.6	GO:0042273	ribosomal large subunit biogenesis(GO:0042273)
0.0	0.0	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0	0.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.0	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0010766	negative regulation of sodium ion transport(GO:0010766)
0.0	0.0	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.1	GO:0035562	negative regulation of chromatin binding(GO:0035562)
0.0	0.0	GO:0072201	negative regulation of mesenchymal cell proliferation(GO:0072201)
0.0	0.0	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.0	0.0	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.1	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.0	GO:0009138	pyrimidine nucleoside diphosphate metabolic process(GO:0009138)
0.0	0.0	GO:0006670	sphingosine metabolic process(GO:0006670)
0.0	0.0	GO:1901897	regulation of relaxation of cardiac muscle(GO:1901897)
0.0	0.1	GO:0051409	response to nitrosative stress(GO:0051409)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.2	0.5	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	1.2	GO:0070852	cell body fiber(GO:0070852)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.3	GO:0031094	platelet dense tubular network(GO:0031094)
0.1	0.2	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.1	0.3	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1	0.2	GO:0097427	microtubule bundle(GO:0097427)
0.1	0.2	GO:0035339	SPOTS complex(GO:0035339)
0.1	0.4	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.1	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	0.1	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.2	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0005712	chiasma(GO:0005712)
0.0	0.7	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.1	GO:0005968	Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.2	GO:0019907	cyclin-dependent protein kinase activating kinase holoenzyme complex(GO:0019907)
0.0	0.2	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0	0.1	GO:0000125	PCAF complex(GO:0000125)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.3	GO:0008250	oligosaccharyltransferase complex(GO:0008250)
0.0	0.5	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.3	GO:0030669	clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0	0.2	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.0	0.2	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0000439	core TFIIH complex(GO:0000439)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.1	GO:0048500	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.2	GO:0032797	SMN complex(GO:0032797)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.0	GO:0032127	dense core granule membrane(GO:0032127)
0.0	0.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.9	GO:0009295	nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0	0.1	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.1	GO:0032009	early phagosome(GO:0032009)
0.0	0.1	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	0.1	GO:0016272	prefoldin complex(GO:0016272)
0.0	0.1	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.1	GO:0045180	basal cortex(GO:0045180)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0071942	XPC complex(GO:0071942)
0.0	0.1	GO:0005851	eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0	0.0	GO:0034750	Scrib-APC-beta-catenin complex(GO:0034750)
0.0	0.1	GO:0005915	zonula adherens(GO:0005915)
0.0	0.2	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.0	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.0	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.2	GO:0031143	pseudopodium(GO:0031143)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.0	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.1	GO:0005726	perichromatin fibrils(GO:0005726)
0.0	0.1	GO:0000444	MIS12/MIND type complex(GO:0000444)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0030120	vesicle coat(GO:0030120)
0.0	0.0	GO:0033647	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.1	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.0	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.2	GO:0005916	fascia adherens(GO:0005916)
0.0	0.5	GO:0014704	intercalated disc(GO:0014704)
0.0	0.0	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.0	0.0	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.0	GO:0031084	BLOC-2 complex(GO:0031084)
0.0	0.1	GO:0005675	holo TFIIH complex(GO:0005675)
0.0	0.0	GO:0070939	Dsl1p complex(GO:0070939)
0.0	0.1	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0008074	guanylate cyclase complex, soluble(GO:0008074)
0.0	0.1	GO:0071546	pi-body(GO:0071546)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.1	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.1	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.0	GO:0097413	Lewy body(GO:0097413)
0.0	0.0	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0008290	F-actin capping protein complex(GO:0008290)
0.0	1.1	GO:0030176	integral component of endoplasmic reticulum membrane(GO:0030176)
0.0	0.0	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.1	GO:0005742	mitochondrial outer membrane translocase complex(GO:0005742)
0.0	0.4	GO:0005747	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.1	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	0.0	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.0	GO:0000275	mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0	0.0	GO:1990745	EARP complex(GO:1990745)
0.0	0.1	GO:0005662	DNA replication factor A complex(GO:0005662)
0.0	0.0	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.2	0.6	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.2	0.5	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.2	0.5	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.1	0.4	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.4	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.1	0.3	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	1.4	GO:0015643	toxic substance binding(GO:0015643)
0.1	0.7	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1	0.3	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.1	0.3	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1	0.7	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.8	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0017040	ceramidase activity(GO:0017040)
0.1	0.3	GO:0004457	lactate dehydrogenase activity(GO:0004457)
0.1	0.2	GO:0032190	acrosin binding(GO:0032190)
0.1	0.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.1	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1	0.6	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.2	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.0	0.1	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.1	GO:0030158	protein xylosyltransferase activity(GO:0030158)
0.0	0.5	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.2	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	0.2	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.0	0.1	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.1	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0005119	smoothened binding(GO:0005119)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.2	GO:0019784	NEDD8-specific protease activity(GO:0019784)
0.0	0.2	GO:0051920	peroxiredoxin activity(GO:0051920)
0.0	0.2	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.3	GO:0008430	selenium binding(GO:0008430)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.0	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.1	GO:0015111	iodide transmembrane transporter activity(GO:0015111)
0.0	0.2	GO:0043426	MRF binding(GO:0043426)
0.0	0.2	GO:0071253	connexin binding(GO:0071253)
0.0	0.3	GO:0043798	cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0	0.2	GO:0019870	potassium channel inhibitor activity(GO:0019870)
0.0	0.1	GO:0019145	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0070137	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.3	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.1	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0008515	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.1	GO:0035662	Toll-like receptor 4 binding(GO:0035662)
0.0	0.1	GO:0008823	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.1	GO:0016015	morphogen activity(GO:0016015)
0.0	0.2	GO:1990247	N6-methyladenosine-containing RNA binding(GO:1990247)
0.0	0.5	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.1	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.1	GO:0033695	oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.0	0.2	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.5	GO:0043014	alpha-tubulin binding(GO:0043014)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.3	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.1	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0016520	growth hormone-releasing hormone receptor activity(GO:0016520)
0.0	0.2	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.0	0.2	GO:0019206	nucleoside kinase activity(GO:0019206)
0.0	0.1	GO:0003810	protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0	0.2	GO:0008641	small protein activating enzyme activity(GO:0008641)
0.0	0.1	GO:0015277	kainate selective glutamate receptor activity(GO:0015277)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0004514	nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0016661	oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0	0.1	GO:0032422	purine-rich negative regulatory element binding(GO:0032422)
0.0	0.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0015266	protein channel activity(GO:0015266)
0.0	0.1	GO:0003909	DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0	0.1	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0086080	protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0	0.1	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0022820	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0003997	acyl-CoA oxidase activity(GO:0003997)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.0	GO:0097109	neuroligin family protein binding(GO:0097109)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0016888	endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.0	0.1	GO:0004383	guanylate cyclase activity(GO:0004383)
0.0	0.3	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.1	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.0	0.0	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0005375	copper ion transmembrane transporter activity(GO:0005375)
0.0	0.9	GO:0002039	p53 binding(GO:0002039)
0.0	0.2	GO:0050998	nitric-oxide synthase binding(GO:0050998)
0.0	0.2	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0051371	muscle alpha-actinin binding(GO:0051371)
0.0	0.0	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.2	GO:0015095	magnesium ion transmembrane transporter activity(GO:0015095)
0.0	0.0	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0034713	type I transforming growth factor beta receptor binding(GO:0034713)
0.0	0.3	GO:0030552	cAMP binding(GO:0030552)
0.0	0.1	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.0	GO:0004771	sterol esterase activity(GO:0004771)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.2	GO:0043539	protein serine/threonine kinase activator activity(GO:0043539)
0.0	0.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0004534	5'-3' exoribonuclease activity(GO:0004534)
0.0	0.2	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.0	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0	0.0	GO:0004471	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.0	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0044548	S100 protein binding(GO:0044548)
0.0	0.0	GO:0002046	opsin binding(GO:0002046)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.2	GO:0019825	oxygen binding(GO:0019825)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.2	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.0	GO:0015216	adenine nucleotide transmembrane transporter activity(GO:0000295) purine ribonucleotide transmembrane transporter activity(GO:0005346) purine nucleotide transmembrane transporter activity(GO:0015216)
0.0	0.0	GO:0071532	ankyrin repeat binding(GO:0071532)
0.0	0.1	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.1	GO:0015385	sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0	0.0	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0017128	phospholipid scramblase activity(GO:0017128)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.4	GO:0016763	transferase activity, transferring pentosyl groups(GO:0016763)
0.0	0.1	GO:0098505	G-rich strand telomeric DNA binding(GO:0098505)
0.0	0.1	GO:0017160	Ral GTPase binding(GO:0017160)
0.0	0.0	GO:0089720	caspase binding(GO:0089720)
0.0	0.0	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.0	GO:0004300	enoyl-CoA hydratase activity(GO:0004300)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.2	GO:0030742	GTP-dependent protein binding(GO:0030742)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.1	GO:0050750	low-density lipoprotein particle receptor binding(GO:0050750)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.7	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.0	ST B CELL ANTIGEN RECEPTOR	B Cell Antigen Receptor
0.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.1	ST PAC1 RECEPTOR PATHWAY	PAC1 Receptor Pathway
0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.1	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.5	PID AURORA A PATHWAY	Aurora A signaling
1.0	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.8	PID P73PATHWAY	p73 transcription factor network
0.3	PID SYNDECAN 2 PATHWAY	Syndecan-2-mediated signaling events
0.0	PID SHP2 PATHWAY	SHP2 signaling
0.0	ST DIFFERENTIATION PATHWAY IN PC12 CELLS	Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.1	PID ECADHERIN KERATINOCYTE PATHWAY	E-cadherin signaling in keratinocytes
0.1	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3	PID ER NONGENOMIC PATHWAY	Plasma membrane estrogen receptor signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.4	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.3	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.1	REACTOME ERK MAPK TARGETS	Genes involved in ERK/MAPK targets
0.0	0.0	REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION	Genes involved in RORA Activates Circadian Expression
0.0	0.6	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.0	0.7	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.7	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.0	0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.9	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.2	REACTOME SHC1 EVENTS IN ERBB4 SIGNALING	Genes involved in SHC1 events in ERBB4 signaling
0.0	0.4	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.3	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	0.2	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.0	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.0	0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.9	REACTOME PHASE II CONJUGATION	Genes involved in Phase II conjugation
0.0	0.6	REACTOME AMINE LIGAND BINDING RECEPTORS	Genes involved in Amine ligand-binding receptors
0.0	0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.0	0.4	REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING	Genes involved in Transferrin endocytosis and recycling
0.0	0.2	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.2	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.2	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.2	REACTOME AMINE DERIVED HORMONES	Genes involved in Amine-derived hormones
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.4	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.1	REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION	Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.4	REACTOME BIOLOGICAL OXIDATIONS	Genes involved in Biological oxidations
0.0	0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.0	0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0	0.2	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0	0.1	REACTOME ANDROGEN BIOSYNTHESIS	Genes involved in Androgen biosynthesis
0.0	1.4	REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES	Genes involved in Metabolism of amino acids and derivatives
0.0	0.0	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.0	0.1	REACTOME MTORC1 MEDIATED SIGNALLING	Genes involved in mTORC1-mediated signalling
0.0	0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2