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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Tbx19

Z-value: 1.75

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Transcription factors associated with Tbx19

Gene Symbol	Gene ID	Gene Info
Tbx19 Ensembl NCBI MGI UniProt	ENSMUSG00000026572.5	T-box 19

Activity of the Tbx19 motif across conditions

Conditions sorted by the z-value of the Tbx19 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr15_34500771_34501210	2.47	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	5667	0.12
chr15_34501595_34501764	1.27	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	6356	0.12
chr15_34501830_34501985	1.22	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	6584	0.12
chr7_97415349_97415810	0.91	Thrsp	thyroid hormone responsive	1940	0.23
chr5_105730043_105730194	0.85	Lrrc8d	leucine rich repeat containing 8D	1271	0.51
chr6_24610042_24610446	0.84	Lmod2	leiomodin 2 (cardiac)	12482	0.14
chr19_44402814_44402965	0.81	Scd1	stearoyl-Coenzyme A desaturase 1	3801	0.18
chr8_36265077_36265268	0.77	Lonrf1	LON peptidase N-terminal domain and ring finger 1	15656	0.2
chr17_34107373_34107524	0.73	Brd2	bromodomain containing 2	6284	0.05
chr13_60479839_60480430	0.73	Gm48500	predicted gene, 48500	1164	0.45
chr3_51230122_51230437	0.71	Gm38357	predicted gene, 38357	1638	0.29
chr1_21266470_21266781	0.71	Gm28836	predicted gene 28836	4968	0.12
chr7_66801636_66801787	0.69	Cers3	ceramide synthase 3	37542	0.13
chr14_21422563_21422878	0.68	Gm25864	predicted gene, 25864	27754	0.17
chr16_18340292_18340462	0.65	Tango2	transport and golgi organization 2	1299	0.25
chr5_130026986_130027142	0.63	Asl	argininosuccinate lyase	2045	0.2
chr15_34501373_34501524	0.61	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	6125	0.12
chr2_91195754_91195905	0.60	Nr1h3	nuclear receptor subfamily 1, group H, member 3	678	0.51
chr5_24961125_24961358	0.60	1500035N22Rik	RIKEN cDNA 1500035N22 gene	24601	0.15
chr13_107763794_107763945	0.59	Zswim6	zinc finger SWIM-type containing 6	15587	0.23
chr10_15746557_15746708	0.59	Gm32283	predicted gene, 32283	7810	0.18
chr11_4905764_4906019	0.57	Thoc5	THO complex 5	3679	0.15
chr8_122047070_122047266	0.56	Banp	BTG3 associated nuclear protein	46321	0.11
chr8_36290613_36290918	0.55	Lonrf1	LON peptidase N-terminal domain and ring finger 1	41249	0.14
chr2_31501565_31501761	0.55	Ass1	argininosuccinate synthetase 1	937	0.56
chr1_67187795_67187968	0.55	Gm15668	predicted gene 15668	61319	0.11
chr9_109966945_109967106	0.54	Map4	microtubule-associated protein 4	1992	0.21
chr2_6209909_6210643	0.54	Echdc3	enoyl Coenzyme A hydratase domain containing 3	2703	0.24
chr13_93618232_93618425	0.54	Gm15622	predicted gene 15622	7054	0.17
chr6_90472539_90472832	0.53	Klf15	Kruppel-like factor 15	5567	0.11
chr19_34524558_34524859	0.51	Lipa	lysosomal acid lipase A	2703	0.19
chr7_16526304_16526474	0.51	Gm17981	predicted gene, 17981	11251	0.12
chr15_81247450_81247602	0.51	8430426J06Rik	RIKEN cDNA 8430426J06 gene	362	0.83
chr11_98755184_98755335	0.50	Thra	thyroid hormone receptor alpha	1673	0.21
chr19_44393747_44393961	0.50	Scd1	stearoyl-Coenzyme A desaturase 1	12836	0.14
chr7_84129291_84129727	0.49	Abhd17c	abhydrolase domain containing 17C	18306	0.14
chr15_95835869_95836082	0.48	Gm17546	predicted gene, 17546	5903	0.16
chr1_63122681_63122832	0.48	Gm20342	predicted gene, 20342	5638	0.1
chr1_181468293_181468488	0.47	Gm16539	predicted gene 16539	35990	0.14
chr1_67197384_67197535	0.47	Gm15668	predicted gene 15668	51741	0.13
chr15_52563909_52564070	0.46	Gm23267	predicted gene, 23267	64333	0.11
chr10_40079067_40079342	0.46	Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	2599	0.21
chr6_50773105_50773295	0.46	C530044C16Rik	RIKEN cDNA C530044C16 gene	2915	0.22
chr9_42769307_42769458	0.45	Grik4	glutamate receptor, ionotropic, kainate 4	39317	0.19
chr5_21795907_21796066	0.44	Psmc2	proteasome (prosome, macropain) 26S subunit, ATPase 2	1883	0.25
chr6_108454056_108454259	0.43	Itpr1	inositol 1,4,5-trisphosphate receptor 1	4546	0.21
chr4_33467139_33467300	0.43	Gm11935	predicted gene 11935	14330	0.21
chr1_131548025_131548226	0.43	Fam72a	family with sequence similarity 72, member A	20222	0.13
chr1_67213641_67214357	0.43	Gm15668	predicted gene 15668	35201	0.17
chr1_133694912_133695208	0.42	Lax1	lymphocyte transmembrane adaptor 1	4952	0.15
chr7_19684170_19684408	0.42	Apoc4	apolipoprotein C-IV	2810	0.1
chr11_118454196_118454347	0.41	Gm11747	predicted gene 11747	724	0.56
chr14_31635979_31636159	0.41	Gm49387	predicted gene, 49387	4809	0.15
chr19_44398143_44398357	0.40	Scd1	stearoyl-Coenzyme A desaturase 1	8440	0.15
chr4_139519783_139519977	0.40	Iffo2	intermediate filament family orphan 2	10668	0.18
chr3_58427270_58427444	0.40	Tsc22d2	TSC22 domain family, member 2	9873	0.19
chr1_13670836_13671022	0.39	Xkr9	X-linked Kx blood group related 9	2158	0.29
chr5_22587487_22587999	0.39	Gm9057	predicted gene 9057	23786	0.11
chr1_88269284_88269537	0.39	Hjurp	Holliday junction recognition protein	18	0.96
chr6_144071228_144071403	0.39	Sox5os1	SRY (sex determining region Y)-box 5, opposite strand 1	49407	0.17
chr11_102152719_102152892	0.39	Tmem101	transmembrane protein 101	3542	0.1
chr6_148209143_148209294	0.39	Ergic2	ERGIC and golgi 2	2759	0.21
chr3_18241613_18241838	0.39	Cyp7b1	cytochrome P450, family 7, subfamily b, polypeptide 1	1613	0.45
chr14_7827742_7828144	0.39	Flnb	filamin, beta	9986	0.16
chr4_45443336_45443487	0.38	Slc25a51	solute carrier family 25, member 51	34645	0.11
chr7_94427849_94428131	0.38	Gm44602	predicted gene 44602	47590	0.17
chr4_45481507_45481658	0.38	Shb	src homology 2 domain-containing transforming protein B	1220	0.43
chr14_61438447_61438598	0.38	Kpna3	karyopherin (importin) alpha 3	1352	0.34
chr8_35418297_35418448	0.37	Gm45301	predicted gene 45301	8866	0.16
chr10_24835678_24835882	0.37	Enpp3	ectonucleotide pyrophosphatase/phosphodiesterase 3	333	0.88
chr11_106055229_106055380	0.37	Gm11646	predicted gene 11646	3452	0.13
chr1_9797489_9798048	0.37	Sgk3	serum/glucocorticoid regulated kinase 3	339	0.83
chr9_79719492_79719780	0.37	Col12a1	collagen, type XII, alpha 1	805	0.61
chr19_55549970_55550134	0.37	Vti1a	vesicle transport through interaction with t-SNAREs 1A	169038	0.03
chr18_38176274_38176683	0.37	Pcdh1	protocadherin 1	26685	0.12
chr11_117833930_117834097	0.37	Afmid	arylformamidase	1740	0.17
chr14_120378403_120378554	0.37	Mbnl2	muscleblind like splicing factor 2	763	0.7
chr15_73060279_73060482	0.36	Trappc9	trafficking protein particle complex 9	665	0.74
chr2_3737881_3738032	0.36	Gm13185	predicted gene 13185	17221	0.16
chr9_78508116_78508485	0.36	Gm47430	predicted gene, 47430	12246	0.11
chr19_29668488_29668647	0.36	Ermp1	endoplasmic reticulum metallopeptidase 1	20152	0.17
chr8_90831859_90832023	0.36	Chd9	chromodomain helicase DNA binding protein 9	3085	0.18
chr3_130058674_130059202	0.36	Sec24b	Sec24 related gene family, member B (S. cerevisiae)	1969	0.28
chr6_51635883_51636035	0.36	Gm22914	predicted gene, 22914	14327	0.23
chr5_72220168_72220334	0.36	Atp10d	ATPase, class V, type 10D	16898	0.18
chr1_128613454_128613628	0.35	Cxcr4	chemokine (C-X-C motif) receptor 4	21248	0.2
chr17_84405686_84406042	0.35	Gm24722	predicted gene, 24722	14435	0.2
chr5_134014798_134014973	0.35	1700030N18Rik	RIKEN cDNA 1700030N18 gene	76566	0.08
chr15_97229103_97229537	0.35	Pced1b	PC-esterase domain containing 1B	17787	0.19
chr5_125506718_125506869	0.35	Aacs	acetoacetyl-CoA synthetase	644	0.65
chr7_137312803_137312954	0.35	Ebf3	early B cell factor 3	1038	0.54
chr1_88123301_88123583	0.35	Gm15372	predicted gene 15372	3334	0.08
chrX_166458575_166458751	0.35	Trappc2	trafficking protein particle complex 2	13360	0.13
chr16_26566034_26566204	0.35	Il1rap	interleukin 1 receptor accessory protein	15585	0.24
chr7_43453405_43453618	0.34	Etfb	electron transferring flavoprotein, beta polypeptide	621	0.43
chr6_139852445_139852613	0.34	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	8881	0.22
chr17_55976882_55977076	0.34	Shd	src homology 2 domain-containing transforming protein D	889	0.35
chr6_108837450_108837611	0.34	Edem1	ER degradation enhancer, mannosidase alpha-like 1	1120	0.56
chr13_37854787_37854958	0.34	Rreb1	ras responsive element binding protein 1	3062	0.27
chr1_36874724_36874959	0.34	Gm37506	predicted gene, 37506	2796	0.22
chr11_111975792_111975963	0.34	Gm11679	predicted gene 11679	67701	0.13
chr16_87439512_87439663	0.34	Rwdd2b	RWD domain containing 2B	974	0.45
chr10_89627085_89627236	0.34	Slc17a8	solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8	5907	0.2
chr10_66914558_66914709	0.34	1110002J07Rik	RIKEN cDNA 1110002J07 gene	3106	0.21
chr2_94147420_94147582	0.33	Hsd17b12	hydroxysteroid (17-beta) dehydrogenase 12	10392	0.17
chr6_24046716_24047018	0.33	Slc13a1	solute carrier family 13 (sodium/sulfate symporters), member 1	61704	0.12
chr8_93166590_93166741	0.33	Ces1d	carboxylesterase 1D	3310	0.17
chr5_76924147_76924300	0.33	2310040G07Rik	RIKEN cDNA 2310040G07 gene	4149	0.15
chr19_57537517_57537807	0.33	Gm50285	predicted gene, 50285	6561	0.15
chr6_116896579_116896756	0.33	Gm43926	predicted gene, 43926	56852	0.12
chr9_74702140_74702734	0.33	Gm27233	predicted gene 27233	6825	0.25
chr8_116504568_116504772	0.33	Dynlrb2	dynein light chain roadblock-type 2	304	0.92
chr6_114787500_114787689	0.33	Gm44331	predicted gene, 44331	1796	0.33
chr11_16698294_16698448	0.33	Gm25698	predicted gene, 25698	34340	0.14
chr16_24517847_24518116	0.33	Morf4l1-ps1	mortality factor 4 like 1, pseudogene 1	11413	0.25
chr8_48663447_48663609	0.33	Tenm3	teneurin transmembrane protein 3	11156	0.25
chr12_8507138_8507301	0.33	5033421B08Rik	RIKEN cDNA 5033421B08 gene	3982	0.18
chr17_79999311_79999483	0.33	Gm41625	predicted gene, 41625	17735	0.14
chr8_121646337_121646786	0.32	Zcchc14	zinc finger, CCHC domain containing 14	6340	0.12
chr1_88138022_88138189	0.32	Ugt1a6a	UDP glucuronosyltransferase 1 family, polypeptide A6A	273	0.75
chr2_58790472_58790686	0.32	Upp2	uridine phosphorylase 2	25254	0.18
chr5_21175987_21176254	0.32	Gsap	gamma-secretase activating protein	10135	0.15
chr10_82083691_82083842	0.32	BC024063	cDNA sequence BC024063	413	0.75
chr11_79758158_79758325	0.32	9130204K15Rik	RIKEN cDNA 9130204K15 gene	24646	0.13
chr7_100624440_100624643	0.32	Gm14382	predicted gene 14382	23	0.96
chr10_4781737_4781912	0.32	Esr1	estrogen receptor 1 (alpha)	69173	0.13
chr2_15065214_15065379	0.32	Arl5b	ADP-ribosylation factor-like 5B	2843	0.2
chr18_46656328_46656479	0.32	Gm3734	predicted gene 3734	25596	0.13
chr19_40178466_40178780	0.32	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	8663	0.16
chr16_77466840_77467144	0.32	Gm37063	predicted gene, 37063	9942	0.12
chr1_67191363_67191567	0.32	Gm15668	predicted gene 15668	57735	0.12
chr17_29060889_29061047	0.32	Gm41556	predicted gene, 41556	2739	0.13
chr18_9672403_9672580	0.32	Colec12	collectin sub-family member 12	35104	0.09
chr10_69205907_69206104	0.31	Rhobtb1	Rho-related BTB domain containing 1	2547	0.26
chr15_52377925_52378095	0.31	Gm41322	predicted gene, 41322	67112	0.1
chr1_67143038_67143247	0.31	Cps1	carbamoyl-phosphate synthetase 1	20116	0.22
chr11_119046302_119046504	0.31	Cbx8	chromobox 8	5434	0.17
chr11_28684227_28684558	0.31	2810471M01Rik	RIKEN cDNA 2810471M01 gene	2828	0.27
chr9_43823107_43823578	0.31	Nectin1	nectin cell adhesion molecule 1	2395	0.29
chr2_156203206_156203400	0.31	Phf20	PHD finger protein 20	6547	0.14
chr4_6225587_6225787	0.31	Ubxn2b	UBX domain protein 2B	34589	0.15
chr3_157731356_157731520	0.31	Gm33466	predicted gene, 33466	5030	0.27
chr14_21138478_21138696	0.31	Adk	adenosine kinase	62435	0.12
chr19_37456339_37456518	0.30	Gm23026	predicted gene, 23026	7318	0.13
chr16_97752199_97752361	0.30	Ripk4	receptor-interacting serine-threonine kinase 4	11507	0.2
chr13_46735806_46736396	0.30	Nup153	nucleoporin 153	8161	0.17
chr1_9981778_9981956	0.30	Gm15818	predicted gene 15818	520	0.62
chr13_52819486_52819637	0.30	BB123696	expressed sequence BB123696	62356	0.13
chr12_87895766_87895919	0.30	Gm2022	predicted pseudogene 2022	472	0.56
chr19_44111938_44112122	0.30	Cwf19l1	CWF19-like 1, cell cycle control (S. pombe)	968	0.39
chr13_31506338_31507020	0.30	Foxq1	forkhead box Q1	49455	0.1
chr2_158076982_158077133	0.30	2010009K17Rik	RIKEN cDNA 2010009K17 gene	14740	0.15
chr4_155137056_155137330	0.30	Morn1	MORN repeat containing 1	26503	0.13
chr6_39241464_39242040	0.30	Gm43479	predicted gene 43479	1638	0.32
chr2_72887557_72887708	0.30	Sp3	trans-acting transcription factor 3	53452	0.1
chr6_100848852_100849036	0.30	Ppp4r2	protein phosphatase 4, regulatory subunit 2	3541	0.26
chr16_11410695_11410993	0.30	Snx29	sorting nexin 29	4187	0.27
chr11_100951927_100952102	0.30	Stat3	signal transducer and activator of transcription 3	12474	0.13
chr6_97251308_97251476	0.30	Lmod3	leiomodin 3 (fetal)	1367	0.4
chr7_130645820_130646001	0.30	Tacc2	transforming, acidic coiled-coil containing protein 2	19	0.98
chr8_90829727_90829881	0.30	Chd9	chromodomain helicase DNA binding protein 9	948	0.46
chr13_51646798_51647087	0.30	Gm22806	predicted gene, 22806	1257	0.35
chr13_69531568_69531734	0.30	Tent4a	terminal nucleotidyltransferase 4A	781	0.51
chr9_23224794_23225147	0.29	Bmper	BMP-binding endothelial regulator	1684	0.55
chr19_44403590_44403745	0.29	Scd1	stearoyl-Coenzyme A desaturase 1	3023	0.2
chr18_39301788_39301939	0.29	Gm15336	predicted gene 15336	827	0.63
chr2_79958014_79958183	0.29	Pde1a	phosphodiesterase 1A, calmodulin-dependent	30307	0.24
chr14_70220268_70220419	0.29	Sorbs3	sorbin and SH3 domain containing 3	8354	0.12
chr7_90138739_90138890	0.29	Gm45223	predicted gene 45223	6322	0.12
chr6_90515371_90515537	0.29	Gm44236	predicted gene, 44236	2152	0.21
chr14_8251423_8251762	0.29	Acox2	acyl-Coenzyme A oxidase 2, branched chain	1930	0.34
chr12_98745962_98746154	0.29	Zc3h14	zinc finger CCCH type containing 14	906	0.45
chr10_8951017_8951174	0.29	Gm48728	predicted gene, 48728	854	0.63
chr1_185370452_185370690	0.29	Eprs	glutamyl-prolyl-tRNA synthetase	2974	0.15
chr6_141942226_141942737	0.29	Slco1a1	solute carrier organic anion transporter family, member 1a1	4329	0.26
chr2_90554210_90554639	0.29	Ptprj	protein tyrosine phosphatase, receptor type, J	26223	0.18
chr9_36794561_36794712	0.29	Ei24	etoposide induced 2.4 mRNA	2384	0.2
chr12_110268616_110268767	0.29	Dio3os	deiodinase, iodothyronine type III, opposite strand	9058	0.11
chr8_105169758_105169909	0.29	Cbfb	core binding factor beta	841	0.4
chr6_116068553_116068726	0.29	Tmcc1	transmembrane and coiled coil domains 1	4517	0.2
chr19_55099918_55100172	0.29	Gm31356	predicted gene, 31356	543	0.49
chrX_103288811_103289364	0.28	Gm19200	predicted gene, 19200	117	0.9
chr14_60387250_60387782	0.28	Amer2	APC membrane recruitment 2	9230	0.22
chr9_74530860_74531022	0.28	Gm28622	predicted gene 28622	30437	0.19
chr1_38128833_38129005	0.28	Rev1	REV1, DNA directed polymerase	602	0.7
chr12_41024854_41025032	0.28	Immp2l	IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)	614	0.72
chr5_125388300_125388726	0.28	Ubc	ubiquitin C	673	0.42
chr16_29991132_29991283	0.28	Gm1968	predicted gene 1968	12023	0.16
chr16_22238973_22239124	0.28	Gm26980	predicted gene, 26980	2127	0.2
chr3_62392302_62392453	0.28	Arhgef26	Rho guanine nucleotide exchange factor (GEF) 26	27291	0.21
chr6_85851621_85851788	0.28	Ptges3-ps	prostaglandin E synthase 3, pseudogene	7724	0.09
chr1_159231811_159232536	0.28	Cop1	COP1, E3 ubiquitin ligase	147	0.95
chr1_175624328_175624488	0.28	Fh1	fumarate hydratase 1	1165	0.45
chr4_100258335_100258573	0.28	Gm12706	predicted gene 12706	103605	0.07
chr2_91161315_91161528	0.28	Madd	MAP-kinase activating death domain	1064	0.38
chr15_36275360_36275511	0.28	Rnf19a	ring finger protein 19A	7663	0.12
chr5_102670562_102670781	0.28	Arhgap24	Rho GTPase activating protein 24	54302	0.17
chr17_65940216_65940367	0.28	Twsg1	twisted gastrulation BMP signaling modulator 1	10824	0.13
chr4_150867947_150868379	0.28	Errfi1	ERBB receptor feedback inhibitor 1	13090	0.13
chr4_3574138_3574411	0.28	Tmem68	transmembrane protein 68	253	0.75

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx19

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.0	GO:0006526	arginine biosynthetic process(GO:0006526)
0.1	0.5	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1	0.5	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1	0.4	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1	0.7	GO:0016078	tRNA catabolic process(GO:0016078)
0.1	0.3	GO:0046271	phenylpropanoid catabolic process(GO:0046271)
0.1	0.4	GO:0048550	negative regulation of pinocytosis(GO:0048550)
0.1	0.3	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.1	0.2	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.2	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.1	0.2	GO:0008050	female courtship behavior(GO:0008050)
0.1	0.4	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1	0.2	GO:0006106	fumarate metabolic process(GO:0006106)
0.1	0.3	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.2	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.1	0.2	GO:0060125	negative regulation of growth hormone secretion(GO:0060125)
0.1	0.2	GO:0034140	negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.1	0.3	GO:2000370	positive regulation of clathrin-mediated endocytosis(GO:2000370)
0.1	0.2	GO:0051586	positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.1	0.2	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.3	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.1	0.2	GO:0019086	late viral transcription(GO:0019086)
0.1	0.4	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:0070782	phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.0	0.2	GO:1900194	negative regulation of oocyte maturation(GO:1900194)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.2	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.2	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	1.5	GO:0033141	positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0	0.1	GO:0015842	aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
0.0	0.1	GO:0061010	gall bladder development(GO:0061010)
0.0	0.2	GO:0035356	cellular triglyceride homeostasis(GO:0035356)
0.0	0.1	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.3	GO:1901407	regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0	0.2	GO:0097459	iron ion import into cell(GO:0097459)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.2	GO:0060903	positive regulation of meiosis I(GO:0060903)
0.0	0.1	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.2	GO:0051639	actin filament network formation(GO:0051639)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.1	GO:0090219	negative regulation of lipid kinase activity(GO:0090219)
0.0	0.2	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0060737	prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0	0.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.2	GO:0033564	anterior/posterior axon guidance(GO:0033564)
0.0	0.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.1	GO:1904017	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.1	GO:0070213	protein auto-ADP-ribosylation(GO:0070213)
0.0	0.2	GO:0034625	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.1	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.2	GO:1902018	negative regulation of cilium assembly(GO:1902018)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:0060916	mesenchymal cell proliferation involved in lung development(GO:0060916)
0.0	0.1	GO:0090258	negative regulation of mitochondrial fission(GO:0090258)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.1	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.1	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.3	GO:0052696	flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.0	0.1	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0006901	vesicle coating(GO:0006901)
0.0	0.1	GO:0061072	iris morphogenesis(GO:0061072)
0.0	0.2	GO:0046146	tetrahydrobiopterin metabolic process(GO:0046146)
0.0	0.1	GO:0010756	positive regulation of plasminogen activation(GO:0010756)
0.0	0.0	GO:1901668	regulation of superoxide dismutase activity(GO:1901668)
0.0	0.1	GO:0001996	positive regulation of heart rate by epinephrine-norepinephrine(GO:0001996)
0.0	0.1	GO:0045950	negative regulation of mitotic recombination(GO:0045950)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.0	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.1	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.0	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0	0.1	GO:0043545	Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.0	0.4	GO:0006607	NLS-bearing protein import into nucleus(GO:0006607)
0.0	0.2	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0	0.1	GO:0071947	protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0	0.1	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.0	0.1	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.1	GO:0042520	positive regulation of tyrosine phosphorylation of Stat4 protein(GO:0042520)
0.0	0.1	GO:0016237	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.1	GO:2000002	negative regulation of DNA damage checkpoint(GO:2000002)
0.0	0.1	GO:0032802	low-density lipoprotein particle receptor catabolic process(GO:0032802) regulation of low-density lipoprotein particle receptor catabolic process(GO:0032803)
0.0	0.1	GO:0042796	snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.2	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0035553	oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.0	GO:0002581	negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.0	0.1	GO:0015867	ATP transport(GO:0015867)
0.0	0.1	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0048007	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0	0.1	GO:0021779	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0	0.1	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0	0.2	GO:0009143	nucleoside triphosphate catabolic process(GO:0009143)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.2	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0042726	flavin-containing compound metabolic process(GO:0042726)
0.0	0.1	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.0	GO:0002278	eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0	0.1	GO:0000710	meiotic mismatch repair(GO:0000710)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:1900246	positive regulation of RIG-I signaling pathway(GO:1900246)
0.0	0.1	GO:0060662	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.0	0.1	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.0	GO:0000459	exonucleolytic trimming involved in rRNA processing(GO:0000459) exonucleolytic trimming to generate mature 3'-end of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000467)
0.0	0.1	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
0.0	0.0	GO:2000313	fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0	0.0	GO:0032483	regulation of Rab protein signal transduction(GO:0032483)
0.0	0.1	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.1	GO:0021943	formation of radial glial scaffolds(GO:0021943)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.0	GO:1901252	regulation of intracellular transport of viral material(GO:1901252)
0.0	0.1	GO:0010988	regulation of low-density lipoprotein particle clearance(GO:0010988)
0.0	0.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0043456	regulation of pentose-phosphate shunt(GO:0043456)
0.0	0.1	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.0	GO:0052405	negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0	0.1	GO:0042436	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:1900364	negative regulation of mRNA polyadenylation(GO:1900364)
0.0	0.0	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0044704	single-organism reproductive behavior(GO:0044704)
0.0	0.1	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.0	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0010992	ubiquitin homeostasis(GO:0010992)
0.0	0.0	GO:0070948	regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.0	GO:0006543	glutamine catabolic process(GO:0006543)
0.0	0.2	GO:0016339	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0	0.1	GO:0021869	forebrain ventricular zone progenitor cell division(GO:0021869)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.0	GO:0046552	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.0	0.2	GO:0051084	'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.0	0.0	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.0	GO:1902031	regulation of NADP metabolic process(GO:1902031)
0.0	0.1	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0	0.0	GO:0046084	adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0	0.1	GO:0032534	regulation of microvillus assembly(GO:0032534)
0.0	0.2	GO:0010866	regulation of triglyceride biosynthetic process(GO:0010866)
0.0	0.0	GO:0015744	succinate transport(GO:0015744)
0.0	0.1	GO:0035701	hematopoietic stem cell migration(GO:0035701)
0.0	0.4	GO:0006084	acetyl-CoA metabolic process(GO:0006084)
0.0	0.0	GO:0051136	regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:1903347	negative regulation of bicellular tight junction assembly(GO:1903347)
0.0	0.2	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0010519	negative regulation of phospholipase activity(GO:0010519)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.1	GO:0035457	cellular response to interferon-alpha(GO:0035457)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.1	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)
0.0	0.1	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0045656	negative regulation of monocyte differentiation(GO:0045656)
0.0	0.1	GO:0006490	oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.0	0.0	GO:0015755	fructose transport(GO:0015755)
0.0	0.1	GO:0070102	interleukin-6-mediated signaling pathway(GO:0070102)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0071499	response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.0	0.0	GO:0007158	neuron cell-cell adhesion(GO:0007158)
0.0	0.0	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0035493	SNARE complex assembly(GO:0035493)
0.0	0.0	GO:0061511	centriole elongation(GO:0061511)
0.0	0.0	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.1	GO:0031269	pseudopodium assembly(GO:0031269)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:1904259	regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.0	0.0	GO:0008054	negative regulation of cyclin-dependent protein serine/threonine kinase by cyclin degradation(GO:0008054)
0.0	0.5	GO:0046426	negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0	0.1	GO:0018342	protein prenylation(GO:0018342) prenylation(GO:0097354)
0.0	0.0	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.0	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.2	GO:0006883	cellular sodium ion homeostasis(GO:0006883)
0.0	0.0	GO:0019346	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0	0.0	GO:0021912	regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.0	GO:0008355	olfactory learning(GO:0008355)
0.0	0.1	GO:0061042	vascular wound healing(GO:0061042)
0.0	0.0	GO:0001807	regulation of type IV hypersensitivity(GO:0001807)
0.0	0.0	GO:0021586	pons maturation(GO:0021586)
0.0	0.0	GO:0033629	negative regulation of cell adhesion mediated by integrin(GO:0033629)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.2	GO:0010758	regulation of macrophage chemotaxis(GO:0010758)
0.0	0.0	GO:0070164	negative regulation of adiponectin secretion(GO:0070164)
0.0	0.0	GO:0046098	guanine metabolic process(GO:0046098)
0.0	0.0	GO:0006420	arginyl-tRNA aminoacylation(GO:0006420)
0.0	0.1	GO:0046606	negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0	0.1	GO:0036315	cellular response to sterol(GO:0036315)
0.0	0.0	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0002087	regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0	0.0	GO:0090403	oxidative stress-induced premature senescence(GO:0090403)
0.0	0.0	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.0	GO:0071351	cellular response to interleukin-18(GO:0071351)
0.0	0.1	GO:0046602	regulation of mitotic centrosome separation(GO:0046602)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.2	GO:0048179	activin receptor complex(GO:0048179)
0.1	0.2	GO:0031088	platelet dense granule membrane(GO:0031088)
0.1	0.2	GO:0005593	FACIT collagen trimer(GO:0005593)
0.0	0.4	GO:0042587	glycogen granule(GO:0042587)
0.0	0.5	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0044615	nuclear pore nuclear basket(GO:0044615)
0.0	0.1	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.2	GO:0005827	polar microtubule(GO:0005827)
0.0	0.1	GO:0045298	tubulin complex(GO:0045298)
0.0	0.2	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	0.1	GO:0000220	vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0	0.1	GO:0031428	box C/D snoRNP complex(GO:0031428)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.1	GO:0005853	eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.4	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.2	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0032983	kainate selective glutamate receptor complex(GO:0032983)
0.0	0.0	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.0	GO:0071942	XPC complex(GO:0071942)
0.0	0.0	GO:0097413	Lewy body(GO:0097413)
0.0	0.1	GO:0042613	MHC class II protein complex(GO:0042613)
0.0	0.1	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0033269	internode region of axon(GO:0033269)
0.0	0.2	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.1	GO:0000445	THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0	0.0	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.1	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.2	GO:0071012	catalytic step 1 spliceosome(GO:0071012)
0.0	0.0	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.5	GO:0030964	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.2	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.2	GO:0002102	podosome(GO:0002102)
0.0	0.2	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.2	GO:0005865	striated muscle thin filament(GO:0005865)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.3	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.1	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.2	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.0	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.0	0.1	GO:0005672	transcription factor TFIIA complex(GO:0005672)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.2	0.5	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.5	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1	0.3	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.1	0.6	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1	0.4	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.1	0.2	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.2	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.1	0.3	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.1	0.2	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	0.3	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.1	0.6	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.2	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.1	0.2	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.1	0.2	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.2	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	1.4	GO:0005132	type I interferon receptor binding(GO:0005132)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0052851	cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.0	0.3	GO:0003896	DNA primase activity(GO:0003896)
0.0	0.2	GO:0005042	netrin receptor activity(GO:0005042)
0.0	0.2	GO:0003857	3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0	0.2	GO:0003828	alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.1	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0009374	biotin binding(GO:0009374)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.3	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0004937	alpha1-adrenergic receptor activity(GO:0004937)
0.0	0.3	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.1	GO:0004779	sulfate adenylyltransferase activity(GO:0004779)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.1	GO:0051377	mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.4	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0050291	sphingosine N-acyltransferase activity(GO:0050291)
0.0	0.1	GO:0036402	proteasome-activating ATPase activity(GO:0036402)
0.0	0.1	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.0	0.1	GO:0004082	bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0	0.1	GO:0008199	ferric iron binding(GO:0008199)
0.0	0.2	GO:0008140	cAMP response element binding protein binding(GO:0008140)
0.0	0.3	GO:0005523	tropomyosin binding(GO:0005523)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.0	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0004667	prostaglandin-D synthase activity(GO:0004667)
0.0	0.1	GO:0030976	thiamine pyrophosphate binding(GO:0030976)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0035515	oxidative RNA demethylase activity(GO:0035515)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.4	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.4	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.3	GO:0017081	chloride channel regulator activity(GO:0017081)
0.0	0.2	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0015288	porin activity(GO:0015288)
0.0	0.1	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.1	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.2	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.2	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0004793	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.1	GO:0016742	hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0	0.1	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0	0.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.4	GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.0	GO:0048248	CXCR3 chemokine receptor binding(GO:0048248)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0031559	oxidosqualene cyclase activity(GO:0031559)
0.0	0.1	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.0	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.1	GO:0048273	mitogen-activated protein kinase p38 binding(GO:0048273)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.2	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.0	GO:0008193	tRNA guanylyltransferase activity(GO:0008193)
0.0	0.0	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.0	0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.0	0.1	GO:0004415	hyalurononglucosaminidase activity(GO:0004415)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.0	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0	0.4	GO:0070330	aromatase activity(GO:0070330)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0008318	protein prenyltransferase activity(GO:0008318)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.1	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.0	GO:0047045	testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0	0.0	GO:2001070	starch binding(GO:2001070)
0.0	0.1	GO:0046972	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.0	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.0	GO:0004739	pyruvate dehydrogenase (acetyl-transferring) activity(GO:0004739)
0.0	0.0	GO:0008192	RNA guanylyltransferase activity(GO:0008192)
0.0	0.0	GO:0098639	collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0	0.1	GO:0008190	eukaryotic initiation factor 4E binding(GO:0008190)
0.0	0.1	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.0	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	0.1	GO:0071723	lipopeptide binding(GO:0071723)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.0	GO:0004676	3-phosphoinositide-dependent protein kinase activity(GO:0004676)
0.0	0.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.0	GO:0004800	thyroxine 5'-deiodinase activity(GO:0004800)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	0.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.2	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.0	GO:0004814	arginine-tRNA ligase activity(GO:0004814)
0.0	0.2	GO:0070530	K63-linked polyubiquitin binding(GO:0070530)
0.0	0.0	GO:0004698	calcium-dependent protein kinase C activity(GO:0004698)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.1	GO:0051959	dynein light intermediate chain binding(GO:0051959)
0.0	0.0	GO:0070568	guanylyltransferase activity(GO:0070568)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	PID PDGFRA PATHWAY	PDGFR-alpha signaling pathway
0.1	0.1	ST GA12 PATHWAY	G alpha 12 Pathway
0.0	0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.0	0.0	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0	0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	0.2	PID ALK2 PATHWAY	ALK2 signaling events
0.0	0.1	PID BETA CATENIN DEG PATHWAY	Degradation of beta catenin
0.0	0.3	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	0.1	PID TXA2PATHWAY	Thromboxane A2 receptor signaling
0.0	0.2	PID IL5 PATHWAY	IL5-mediated signaling events
0.0	0.4	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.0	PID MET PATHWAY	Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.8	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.3	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.6	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.4	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS	Genes involved in Synthesis of bile acids and bile salts
0.1	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.2	REACTOME IRAK1 RECRUITS IKK COMPLEX	Genes involved in IRAK1 recruits IKK complex
0.5	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.1	REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE	Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.1	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.2	REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES	Genes involved in Antiviral mechanism by IFN-stimulated genes
0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2	REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN	Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.1	REACTOME NOD1 2 SIGNALING PATHWAY	Genes involved in NOD1/2 Signaling Pathway
0.1	REACTOME EXTENSION OF TELOMERES	Genes involved in Extension of Telomeres
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION	Genes involved in activated TAK1 mediates p38 MAPK activation
0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.1	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling

Results for Tbx19

Z-value: 1.75

Motif logo

Transcription factors associated with Tbx19

Activity of the Tbx19 motif across conditions

Conditions sorted by the z-value of the Tbx19 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx19

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: