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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tbx1_Eomes

Z-value: 0.52

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Transcription factors associated with Tbx1_Eomes

Gene Symbol	Gene ID	Gene Info
Tbx1 Ensembl NCBI MGI UniProt	ENSMUSG00000009097.9	Tbx1
Eomes Ensembl NCBI MGI UniProt	ENSMUSG00000032446.8	Eomes

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Tbx1	chr16_18590521_18590672	75	0.941442	0.56	2.5e-01	Click!
Tbx1	chr16_18574323_18574479	8927	0.121537	0.24	6.5e-01	Click!

Activity of the Tbx1_Eomes motif across conditions

Conditions sorted by the z-value of the Tbx1_Eomes motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr4_11861132_11861344	0.44	Gm25002	predicted gene, 25002	87649	0.07
chr7_100658121_100658314	0.38	Plekhb1	pleckstrin homology domain containing, family B (evectins) member 1	147	0.93
chr1_171454993_171455144	0.37	F11r	F11 receptor	7782	0.1
chr11_20826808_20826959	0.37	Lgalsl	lectin, galactoside binding-like	3872	0.18
chr3_83996881_83997402	0.36	Tmem131l	transmembrane 131 like	28913	0.2
chr1_193271420_193271628	0.35	G0s2	G0/G1 switch gene 2	1693	0.19
chr1_84059698_84059849	0.34	Pid1	phosphotyrosine interaction domain containing 1	6520	0.27
chr5_125296722_125296910	0.32	Scarb1	scavenger receptor class B, member 1	2707	0.22
chr6_146473719_146473882	0.31	Gm15720	predicted gene 15720	10193	0.19
chr5_75046920_75047087	0.30	Gm18593	predicted gene, 18593	1476	0.27
chr2_104123492_104123669	0.30	A930018P22Rik	RIKEN cDNA A930018P22 gene	811	0.53
chr9_110703228_110703412	0.30	Ccdc12	coiled-coil domain containing 12	6574	0.12
chr11_86932862_86933027	0.29	Ypel2	yippee like 2	39080	0.14
chr2_29437237_29437388	0.28	Gm24976	predicted gene, 24976	21882	0.15
chr19_30146095_30146265	0.27	Gldc	glycine decarboxylase	949	0.57
chr2_129101432_129101630	0.27	Polr1b	polymerase (RNA) I polypeptide B	504	0.68
chr1_52388262_52388419	0.26	Gm23460	predicted gene, 23460	56204	0.11
chr2_30386411_30386643	0.24	Miga2	mitoguardin 2	4583	0.1
chr4_97013861_97014018	0.24	Gm27521	predicted gene, 27521	96919	0.08
chr7_112498970_112499146	0.24	Parva	parvin, alpha	20643	0.2
chr15_102181335_102181499	0.23	Csad	cysteine sulfinic acid decarboxylase	1556	0.24
chr10_80972757_80972931	0.23	Gm3828	predicted gene 3828	18134	0.09
chr11_86959315_86959659	0.23	Ypel2	yippee like 2	12537	0.18
chr16_31233513_31233746	0.22	Gm41442	predicted gene, 41442	39	0.96
chr19_42054767_42054919	0.21	4933411K16Rik	RIKEN cDNA 4933411K16 gene	2595	0.16
chr3_31136392_31136619	0.21	Cldn11	claudin 11	13415	0.2
chr6_112873464_112873750	0.21	Srgap3	SLIT-ROBO Rho GTPase activating protein 3	44148	0.13
chrX_73466714_73466865	0.21	Haus7	HAUS augmin-like complex, subunit 7	7745	0.12
chr13_91765048_91765525	0.21	Gm27656	predicted gene, 27656	13180	0.14
chr2_158199719_158199870	0.21	1700060C20Rik	RIKEN cDNA 1700060C20 gene	7786	0.15
chr2_103454731_103454882	0.21	Elf5	E74-like factor 5	6068	0.19
chr11_106581287_106581448	0.21	Tex2	testis expressed gene 2	767	0.66
chr18_36726531_36726874	0.20	Cd14	CD14 antigen	36	0.94
chr17_56208632_56208824	0.20	Dpp9	dipeptidylpeptidase 9	480	0.64
chr2_105901718_105901869	0.20	Elp4	elongator acetyltransferase complex subunit 4	2690	0.24
chr12_82914756_82914931	0.20	1700085C21Rik	RIKEN cDNA 1700085C21 gene	24312	0.21
chr6_28736579_28736738	0.19	Snd1	staphylococcal nuclease and tudor domain containing 1	28032	0.19
chrX_103733822_103734171	0.19	Slc16a2	solute carrier family 16 (monocarboxylic acid transporters), member 2	193	0.92
chr9_71028459_71028669	0.19	Lipc	lipase, hepatic	76338	0.09
chr17_29093649_29093812	0.19	Cdkn1a	cyclin-dependent kinase inhibitor 1A (P21)	39	0.91
chr11_50199089_50199272	0.19	Sqstm1	sequestosome 1	3774	0.13
chr9_108297063_108297481	0.19	Amt	aminomethyltransferase	350	0.72
chr2_167846760_167847264	0.18	Gm14319	predicted gene 14319	11573	0.16
chr14_30906842_30907058	0.18	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	7179	0.11
chr19_28928421_28928869	0.18	4430402I18Rik	RIKEN cDNA 4430402I18 gene	582	0.68
chr9_115400503_115400904	0.18	Gm9487	predicted gene 9487	4446	0.15
chr6_121859844_121860059	0.18	Mug1	murinoglobulin 1	18847	0.19
chr1_58097131_58097333	0.18	Aox3	aldehyde oxidase 3	15898	0.18
chr5_8983164_8983315	0.18	Crot	carnitine O-octanoyltransferase	1095	0.38
chr1_166410038_166410239	0.18	Pogk	pogo transposable element with KRAB domain	275	0.88
chr3_98311224_98311375	0.18	Phgdh	3-phosphoglycerate dehydrogenase	17314	0.14
chr8_114555833_114556014	0.17	Gm16116	predicted gene 16116	38977	0.17
chr6_58832026_58832202	0.17	Herc3	hect domain and RLD 3	253	0.93
chr10_71183397_71183774	0.17	C730027H18Rik	RIKEN cDNA C730027H18 gene	1533	0.26
chr2_126569048_126569199	0.17	Slc27a2	solute carrier family 27 (fatty acid transporter), member 2	4363	0.22
chr3_28025480_28025631	0.17	Pld1	phospholipase D1	5707	0.3
chr11_86976287_86976438	0.17	Ypel2	yippee like 2	4338	0.2
chr6_5512042_5512193	0.17	Pdk4	pyruvate dehydrogenase kinase, isoenzyme 4	15808	0.27
chr14_63265088_63265239	0.17	Gata4	GATA binding protein 4	5961	0.19
chr8_88863392_88863746	0.17	Gm45504	predicted gene 45504	495	0.85
chr6_87846724_87847004	0.16	Cnbp	cellular nucleic acid binding protein	547	0.54
chr15_75996647_75996807	0.16	Mapk15	mitogen-activated protein kinase 15	14	0.94
chr11_101372782_101373038	0.16	G6pc	glucose-6-phosphatase, catalytic	5349	0.06
chr8_120495609_120495777	0.16	Gse1	genetic suppressor element 1, coiled-coil protein	7246	0.15
chr4_144896227_144896412	0.16	Dhrs3	dehydrogenase/reductase (SDR family) member 3	3100	0.28
chr2_26405907_26406058	0.15	Inpp5e	inositol polyphosphate-5-phosphatase E	3145	0.11
chr2_163103270_163103612	0.15	Gm22174	predicted gene, 22174	10542	0.12
chr19_3329840_3329991	0.15	Cpt1a	carnitine palmitoyltransferase 1a, liver	3810	0.15
chr1_182500736_182501185	0.15	Gm37069	predicted gene, 37069	6804	0.14
chr10_21448325_21448476	0.15	Gm48386	predicted gene, 48386	2764	0.21
chr16_46463130_46463327	0.15	Nectin3	nectin cell adhesion molecule 3	14718	0.27
chr2_128567912_128568063	0.15	Gm14006	predicted gene 14006	9753	0.13
chr10_61143598_61144049	0.15	Sgpl1	sphingosine phosphate lyase 1	3075	0.2
chr1_155888091_155888242	0.15	Cep350	centrosomal protein 350	2152	0.22
chr2_92056065_92056235	0.15	2900072N19Rik	RIKEN cDNA 2900072N19 gene	3219	0.2
chr11_109488275_109488451	0.15	Arsg	arylsulfatase G	2757	0.18
chr5_135139962_135140114	0.15	Mlxipl	MLX interacting protein-like	6407	0.11
chr5_121732457_121732668	0.15	Gm16552	predicted gene 16552	5159	0.13
chr6_94182054_94182207	0.15	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	100895	0.08
chr8_124589098_124589249	0.14	Capn9	calpain 9	13060	0.16
chr11_79670395_79670546	0.14	Rab11fip4os2	RAB11 family interacting protein 4 (class II), opposite strand 2	4613	0.13
chr11_53420114_53420567	0.14	Leap2	liver-expressed antimicrobial peptide 2	2830	0.12
chr4_107159322_107159488	0.14	Tceanc2	transcription elongation factor A (SII) N-terminal and central domain containing 2	18263	0.12
chr17_31383992_31384162	0.14	Pde9a	phosphodiesterase 9A	2133	0.25
chr14_65832955_65833117	0.14	Esco2	establishment of sister chromatid cohesion N-acetyltransferase 2	872	0.57
chr2_57332734_57332885	0.14	Gm13535	predicted gene 13535	57123	0.11
chr13_34645504_34645908	0.14	Pxdc1	PX domain containing 1	2862	0.18
chr3_31136684_31136995	0.14	Cldn11	claudin 11	13081	0.2
chr5_145993052_145993431	0.14	Cyp3a25	cytochrome P450, family 3, subfamily a, polypeptide 25	1598	0.28
chr10_61337817_61337968	0.14	Pald1	phosphatase domain containing, paladin 1	4435	0.15
chr11_79230285_79230459	0.13	Wsb1	WD repeat and SOCS box-containing 1	12577	0.16
chr17_86497669_86497820	0.13	Prkce	protein kinase C, epsilon	4417	0.26
chr5_53437072_53437250	0.13	Gm26486	predicted gene, 26486	18588	0.17
chr15_102442382_102442533	0.13	Amhr2	anti-Mullerian hormone type 2 receptor	2910	0.13
chr13_104706600_104706768	0.13	2610204G07Rik	RIKEN cDNA 2610204G07 gene	21753	0.23
chr4_134060274_134060433	0.13	Crybg2	crystallin beta-gamma domain containing 2	462	0.7
chr3_98297519_98297734	0.13	Gm43189	predicted gene 43189	10638	0.14
chr11_85530391_85530542	0.13	Bcas3	breast carcinoma amplified sequence 3	20828	0.21
chr7_141070384_141070555	0.13	B4galnt4	beta-1,4-N-acetyl-galactosaminyl transferase 4	133	0.9
chr19_30202160_30202660	0.13	Gldc	glycine decarboxylase	26981	0.15
chr19_23066702_23066853	0.13	Gm50136	predicted gene, 50136	5304	0.21
chr1_191822042_191822193	0.13	Nek2	NIMA (never in mitosis gene a)-related expressed kinase 2	65	0.58
chr5_137986079_137986259	0.13	Azgp1	alpha-2-glycoprotein 1, zinc	4601	0.1
chr15_97161836_97161987	0.13	Gm32885	predicted gene, 32885	5311	0.27
chr9_77749808_77749964	0.13	Gclc	glutamate-cysteine ligase, catalytic subunit	4649	0.16
chr13_94708250_94708413	0.13	Gm32351	predicted gene, 32351	5613	0.17
chr6_115464997_115465148	0.13	Gm44079	predicted gene, 44079	82	0.97
chr19_29125266_29125417	0.12	Mir101b	microRNA 101b	9938	0.14
chr5_117275916_117276216	0.12	Pebp1	phosphatidylethanolamine binding protein 1	11459	0.11
chr14_73045910_73046229	0.12	Cysltr2	cysteinyl leukotriene receptor 2	3003	0.3
chr10_30810298_30810917	0.12	Ncoa7	nuclear receptor coactivator 7	7281	0.16
chr9_110390754_110390978	0.12	Ptpn23	protein tyrosine phosphatase, non-receptor type 23	391	0.77
chr6_122216632_122216783	0.12	Mug-ps1	murinoglobulin, pseudogene 1	12353	0.15
chr1_167374753_167374904	0.12	Aldh9a1	aldehyde dehydrogenase 9, subfamily A1	10662	0.13
chr5_72654251_72654431	0.12	Nipal1	NIPA-like domain containing 1	6499	0.12
chr9_24378970_24379135	0.12	Gm22380	predicted gene, 22380	27934	0.15
chr5_122494527_122494678	0.12	Gm43360	predicted gene 43360	306	0.77
chr1_178314559_178314724	0.12	B230369F24Rik	RIKEN cDNA B230369F24 gene	3908	0.13
chr10_28178649_28178847	0.12	Gm22370	predicted gene, 22370	35373	0.21
chr16_16888784_16888935	0.12	Top3b	topoisomerase (DNA) III beta	1020	0.34
chr15_89177223_89177386	0.12	Plxnb2	plexin B2	3484	0.11
chrX_143067335_143067542	0.12	Rtl9	retrotransposon Gag like 9	32156	0.2
chr12_79442844_79442995	0.12	Rad51b	RAD51 paralog B	115566	0.06
chr5_145743023_145743196	0.11	Gm43626	predicted gene 43626	17436	0.15
chr11_120526901_120527125	0.11	Gm11789	predicted gene 11789	3541	0.08
chr1_73909397_73909605	0.11	Tns1	tensin 1	18716	0.18
chr11_75437280_75437567	0.11	Serpinf2	serine (or cysteine) peptidase inhibitor, clade F, member 2	1477	0.2
chr1_52816740_52816904	0.11	Inpp1	inositol polyphosphate-1-phosphatase	629	0.71
chr9_43756806_43756967	0.11	Gm30015	predicted gene, 30015	10786	0.15
chr11_7193213_7193425	0.11	Igfbp1	insulin-like growth factor binding protein 1	4463	0.19
chr5_63910906_63911057	0.11	Gm15819	predicted gene 15819	12920	0.16
chr16_24424101_24424681	0.11	Gm24440	predicted gene, 24440	17974	0.17
chr11_22843395_22843546	0.11	Gm23772	predicted gene, 23772	3398	0.15
chr19_37860664_37860851	0.11	Gm4757	predicted gene 4757	9513	0.21
chr1_181005812_181005979	0.11	Ephx1	epoxide hydrolase 1, microsomal	9725	0.09
chr18_44633494_44633779	0.11	A930012L18Rik	RIKEN cDNA A930012L18 gene	28029	0.19
chr15_100414144_100414311	0.11	Gm5475	predicted gene 5475	7920	0.11
chr2_10674812_10674992	0.11	Mir669h	microRNA 669h	156747	0.01
chr11_103011230_103011391	0.11	Dcakd	dephospho-CoA kinase domain containing	5858	0.13
chr17_46484376_46484539	0.11	Ttbk1	tau tubulin kinase 1	162	0.91
chr8_122174579_122174745	0.11	Zfp469	zinc finger protein 469	83958	0.07
chr19_20645058_20645209	0.11	Aldh1a1	aldehyde dehydrogenase family 1, subfamily A1	43172	0.15
chr5_106313971_106314130	0.11	Gm32921	predicted gene, 32921	7290	0.16
chr5_117368668_117368892	0.11	Wsb2	WD repeat and SOCS box-containing 2	5258	0.12
chr4_126067500_126067685	0.11	Rpl28-ps3	ribosomal protein L28, pseudogene 3	2667	0.17
chr4_109143752_109143931	0.11	Osbpl9	oxysterol binding protein-like 9	12769	0.21
chr17_35725713_35725941	0.10	Gm20443	predicted gene 20443	13979	0.08
chr3_145759243_145759445	0.10	Ddah1	dimethylarginine dimethylaminohydrolase 1	669	0.72
chr11_70741343_70741494	0.10	Gm12320	predicted gene 12320	13733	0.08
chr6_143635075_143635226	0.10	1700060C16Rik	RIKEN cDNA 1700060C16 gene	16138	0.27
chr7_3221770_3221921	0.10	Mir295	microRNA 295	1072	0.16
chr15_88870480_88870800	0.10	Pim3	proviral integration site 3	5720	0.14
chr5_45513018_45513181	0.10	Lap3	leucine aminopeptidase 3	3890	0.14
chr2_167755014_167755358	0.10	Gm14321	predicted gene 14321	22281	0.12
chr5_72652767_72652918	0.10	Nipal1	NIPA-like domain containing 1	5000	0.13
chr10_81560885_81561091	0.10	Tle5	TLE family member 5, transcriptional modulator	56	0.93
chr9_31302317_31302496	0.10	Prdm10	PR domain containing 10	11147	0.16
chr7_100120840_100121149	0.10	Pold3	polymerase (DNA-directed), delta 3, accessory subunit	84	0.96
chr19_43893023_43893176	0.10	Dnmbp	dynamin binding protein	2408	0.22
chr6_8510307_8510729	0.10	A430035B10Rik	RIKEN cDNA A430035B10 gene	88	0.91
chr14_47475021_47475196	0.10	Fbxo34	F-box protein 34	931	0.45
chr19_3624054_3624227	0.10	Lrp5	low density lipoprotein receptor-related protein 5	8348	0.16
chr10_127160387_127160730	0.10	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	4667	0.09
chr8_33896084_33896490	0.10	Rbpms	RNA binding protein gene with multiple splicing	4523	0.2
chr19_3687091_3687242	0.10	Lrp5	low density lipoprotein receptor-related protein 5	602	0.61
chr2_72866286_72866437	0.10	6430710C18Rik	RIKEN cDNA 6430710C18 gene	52644	0.12
chr2_30363854_30364005	0.10	Miga2	mitoguardin 2	304	0.79
chr11_119913357_119913544	0.10	Chmp6	charged multivesicular body protein 6	9	0.97
chr11_102211338_102211489	0.10	Hdac5	histone deacetylase 5	7515	0.09
chr11_100859548_100859739	0.10	Stat5a	signal transducer and activator of transcription 5A	13	0.97
chr18_6208229_6208380	0.10	Gm17036	predicted gene 17036	5609	0.19
chr16_35055198_35055367	0.09	Hacd2	3-hydroxyacyl-CoA dehydratase 2	6667	0.21
chr6_56919800_56919965	0.09	Nt5c3	5'-nucleotidase, cytosolic III	3842	0.15
chr2_27471316_27471526	0.09	Brd3	bromodomain containing 3	3760	0.17
chr1_134344955_134345133	0.09	Tmem183a	transmembrane protein 183A	5261	0.14
chr7_84135967_84136134	0.09	Abhd17c	abhydrolase domain containing 17C	11765	0.15
chr1_74304286_74304581	0.09	Tmbim1	transmembrane BAX inhibitor motif containing 1	28	0.94
chr8_103538740_103538926	0.09	Gm45277	predicted gene 45277	24790	0.23
chr8_124291752_124291934	0.09	Galnt2	polypeptide N-acetylgalactosaminyltransferase 2	3260	0.21
chr4_155207879_155208052	0.09	Ski	ski sarcoma viral oncogene homolog (avian)	14570	0.17
chr4_107159764_107160176	0.09	Tceanc2	transcription elongation factor A (SII) N-terminal and central domain containing 2	17698	0.12
chr6_30302088_30302239	0.09	Ube2h	ubiquitin-conjugating enzyme E2H	2359	0.22
chr8_126727960_126728150	0.09	Gm45805	predicted gene 45805	30279	0.2
chr6_137747661_137747817	0.09	Strap	serine/threonine kinase receptor associated protein	1486	0.45
chr5_89416345_89416742	0.09	Gc	vitamin D binding protein	19085	0.24
chr17_84990758_84990958	0.09	Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	2815	0.25
chr11_101554799_101555209	0.09	Nbr1	NBR1, autophagy cargo receptor	862	0.39
chr3_54723479_54723643	0.09	Exosc8	exosome component 8	5897	0.14
chr15_91276343_91276512	0.09	CN725425	cDNA sequence CN725425	44849	0.16
chr7_112187666_112187837	0.09	Dkk3	dickkopf WNT signaling pathway inhibitor 3	28694	0.2
chr13_64361503_64361746	0.09	Gm49230	predicted gene, 49230	113	0.86
chr15_34510659_34511041	0.09	Pop1	processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)	943	0.43
chr2_132240536_132240711	0.09	Tmem230	transmembrane protein 230	7031	0.15
chr4_137875186_137875337	0.08	Gm13012	predicted gene 13012	8151	0.2
chr2_6074858_6075460	0.08	Upf2	UPF2 regulator of nonsense transcripts homolog (yeast)	24732	0.16
chr12_80832436_80832620	0.08	Susd6	sushi domain containing 6	36180	0.11
chrX_163908542_163908757	0.08	Ap1s2	adaptor-related protein complex 1, sigma 2 subunit	368	0.89
chr8_72222949_72223319	0.08	Fam32a	family with sequence similarity 32, member A	3370	0.12
chr11_109500636_109500796	0.08	Gm22378	predicted gene, 22378	892	0.5
chrX_60339140_60339308	0.08	Mir505	microRNA 505	55268	0.12

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx1_Eomes

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.2	GO:0071727	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.2	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.1	GO:0046439	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.2	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.1	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.1	GO:0035461	vitamin transmembrane transport(GO:0035461)
0.0	0.1	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.1	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.2	GO:0007000	nucleolus organization(GO:0007000)
0.0	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.1	GO:2000504	positive regulation of blood vessel remodeling(GO:2000504)
0.0	0.2	GO:0071493	cellular response to UV-B(GO:0071493)
0.0	0.1	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.1	GO:0010982	regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.0	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.0	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0048319	axial mesoderm morphogenesis(GO:0048319)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0010510	regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0	0.0	GO:0009436	glyoxylate catabolic process(GO:0009436)
0.0	0.0	GO:0001712	ectodermal cell fate commitment(GO:0001712)
0.0	0.0	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.0	0.0	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.0	GO:0035441	cell migration involved in vasculogenesis(GO:0035441)
0.0	0.0	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.0	GO:0035910	ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.0	0.1	GO:2000643	positive regulation of early endosome to late endosome transport(GO:2000643)
0.0	0.1	GO:0071918	urea transmembrane transport(GO:0071918)
0.0	0.1	GO:0071670	smooth muscle cell chemotaxis(GO:0071670)
0.0	0.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.0	0.0	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0006627	protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.0	GO:0006499	N-terminal protein myristoylation(GO:0006499)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.1	GO:0005610	laminin-5 complex(GO:0005610)
0.2	GO:0005736	DNA-directed RNA polymerase I complex(GO:0005736)
0.0	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	GO:0097425	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	GO:0000815	ESCRT III complex(GO:0000815)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.2	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.1	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.2	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.1	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.2	GO:0001054	RNA polymerase I activity(GO:0001054)
0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	GO:0004740	pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0	GO:0004096	catalase activity(GO:0004096)
0.0	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.1	GO:0005534	galactose binding(GO:0005534)
0.2	GO:0016594	glycine binding(GO:0016594)
0.0	GO:0030911	TPR domain binding(GO:0030911)
0.2	GO:0008483	transaminase activity(GO:0008483)
0.1	GO:0019957	C-C chemokine binding(GO:0019957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	SA G2 AND M PHASES	Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.0	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.2	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand