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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Tbx5

Z-value: 0.79

Motif logo

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Transcription factors associated with Tbx5

Gene Symbol Gene ID Gene Info
Tbx5
ENSMUSG00000018263.8 T-box 5

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr5_119839110_119839360Tbx530800.227585-0.167.6e-01Click!

Activity of the Tbx5 motif across conditions

Conditions sorted by the z-value of the Tbx5 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr2_31517780_31518546 0.34 Ass1
 argininosuccinate synthetase 1
 327
 0.88
chr10_117649861_117650065 0.30 Gm25709
 predicted gene, 25709
 12425
 0.13
chr4_117116805_117116956 0.30 Ptch2
 patched 2
 3456
 0.09
chrX_169982545_169982696 0.29 Gm15726
 predicted gene 15726
 2612
 0.19
chr17_45873270_45873443 0.28 4930542M03Rik
 RIKEN cDNA 4930542M03 gene
 8096
 0.17
chr3_83043842_83044694 0.26 Fgb
 fibrinogen beta chain
 5595
 0.15
chr7_89699637_89700074 0.25 Me3
 malic enzyme 3, NADP(+)-dependent, mitochondrial
 36876
 0.14
chr3_51254730_51254881 0.22 Elf2
 E74-like factor 2
 5436
 0.14
chr8_119416779_119416930 0.21 Osgin1
 oxidative stress induced growth inhibitor 1
 17270
 0.13
chr8_119417171_119417322 0.21 Osgin1
 oxidative stress induced growth inhibitor 1
 16878
 0.13
chr3_28025480_28025631 0.21 Pld1
 phospholipase D1
 5707
 0.3
chr7_13007324_13007475 0.21 Zbtb45
 zinc finger and BTB domain containing 45
 2401
 0.12
chr12_109798285_109798857 0.21 Gm9661
 predicted gene 9661
 28432
 0.03
chr2_26314444_26314595 0.20 Gpsm1
 G-protein signalling modulator 1 (AGS3-like, C. elegans)
 996
 0.38
chr16_25221689_25221840 0.20 Tprg
 transformation related protein 63 regulated
 65053
 0.14
chr19_4033739_4033961 0.19 Gstp1
 glutathione S-transferase, pi 1
 2143
 0.11
chr3_100892764_100892976 0.19 Trim45
 tripartite motif-containing 45
 29332
 0.16
chr9_98424555_98424727 0.19 Rbp1
 retinol binding protein 1, cellular
 1680
 0.4
chr8_46483334_46483691 0.19 Acsl1
 acyl-CoA synthetase long-chain family member 1
 7454
 0.16
chr18_63901771_63901922 0.18 Gm19076
 predicted gene, 19076
 2815
 0.29
chr2_31519156_31519420 0.18 Ass1
 argininosuccinate synthetase 1
 798
 0.61
chr11_83740503_83740922 0.18 Wfdc21
 WAP four-disulfide core domain 21
 6228
 0.1
chr8_12798830_12798981 0.18 Atp11a
 ATPase, class VI, type 11A
 12511
 0.15
chrX_140539340_140539749 0.18 Tsc22d3
 TSC22 domain family, member 3
 3124
 0.26
chr11_118454196_118454347 0.17 Gm11747
 predicted gene 11747
 724
 0.56
chr2_25095172_25095346 0.17 Noxa1
 NADPH oxidase activator 1
 110
 0.92
chr11_16881299_16881793 0.17 Egfr
 epidermal growth factor receptor
 3396
 0.26
chr9_98423199_98423389 0.17 Rbp1
 retinol binding protein 1, cellular
 333
 0.9
chr5_139822534_139822685 0.17 Tmem184a
 transmembrane protein 184a
 2692
 0.17
chr9_85551927_85552078 0.17 Gm48834
 predicted gene, 48834
 1763
 0.42
chr15_88866027_88866463 0.17 Pim3
 proviral integration site 3
 1325
 0.34
chr7_98415563_98415739 0.17 Gm44507
 predicted gene 44507
 27
 0.97
chr10_98652216_98652384 0.17 Gm5427
 predicted gene 5427
 47410
 0.18
chr16_23967660_23967916 0.17 Bcl6
 B cell leukemia/lymphoma 6
 4592
 0.19
chr10_93492422_93492688 0.17 Hal
 histidine ammonia lyase
 3752
 0.18
chr9_121906088_121906239 0.16 Ackr2
 atypical chemokine receptor 2
 1
 0.95
chr11_97383324_97383535 0.16 Socs7
 suppressor of cytokine signaling 7
 5992
 0.15
chr11_117322484_117322692 0.16 Septin9
 septin 9
 3845
 0.24
chr14_41120981_41121358 0.16 Sftpa1
 surfactant associated protein A1
 10613
 0.11
chr17_86208576_86208727 0.16 AC154542.1
 TEC
 33076
 0.17
chr11_101372782_101373038 0.16 G6pc
 glucose-6-phosphatase, catalytic
 5349
 0.06
chr6_34412803_34412954 0.16 Akr1b7
 aldo-keto reductase family 1, member B7
 544
 0.69
chr11_116180328_116180538 0.16 Acox1
 acyl-Coenzyme A oxidase 1, palmitoyl
 781
 0.44
chr17_56005828_56005982 0.16 Mpnd
 MPN domain containing
 194
 0.61
chr17_8974900_8975051 0.16 1700010I14Rik
 RIKEN cDNA 1700010I14 gene
 13358
 0.23
chr12_110203702_110203885 0.16 Gm34785
 predicted gene, 34785
 15732
 0.12
chr6_86665663_86665814 0.15 Gm44292
 predicted gene, 44292
 187
 0.89
chr2_144308533_144308857 0.15 Ovol2
 ovo like zinc finger 2
 22631
 0.09
chr19_46029534_46029692 0.15 Ldb1
 LIM domain binding 1
 5265
 0.14
chr7_92681661_92681812 0.15 Pcf11
 PCF11 cleavage and polyadenylation factor subunit
 11802
 0.12
chr2_155063372_155063735 0.15 Gm45609
 predicted gene 45609
 10628
 0.13
chr1_88960128_88960297 0.15 Gm4753
 predicted gene 4753
 27893
 0.17
chr5_120480072_120480223 0.15 Sds
 serine dehydratase
 216
 0.8
chr18_11144853_11145048 0.15 Gata6
 GATA binding protein 6
 85903
 0.09
chr7_84596857_84597020 0.15 Fah
 fumarylacetoacetate hydrolase
 5162
 0.17
chr4_41637175_41637517 0.15 Gm12406
 predicted gene 12406
 2032
 0.17
chr19_44997151_44997302 0.15 Sema4g
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
 5090
 0.11
chr17_39846008_39846161 0.15 CT010467.1
 18s RNA, related sequence 5
 269
 0.9
chr6_134078837_134079020 0.15 Gm43982
 predicted gene, 43982
 5574
 0.2
chr3_102187285_102187460 0.15 Vangl1
 VANGL planar cell polarity 1
 10533
 0.14
chr4_150592192_150592343 0.14 Rere
 arginine glutamic acid dipeptide (RE) repeats
 22610
 0.17
chr9_78586353_78586504 0.14 Slc17a5
 solute carrier family 17 (anion/sugar transporter), member 5
 1587
 0.33
chr10_24911578_24911812 0.14 Mir6905
 microRNA 6905
 1031
 0.42
chr7_19496130_19496424 0.14 Exoc3l2
 exocyst complex component 3-like 2
 7221
 0.08
chr4_135231252_135231420 0.14 Clic4
 chloride intracellular channel 4 (mitochondrial)
 41478
 0.11
chr7_140765024_140765175 0.14 Cyp2e1
 cytochrome P450, family 2, subfamily e, polypeptide 1
 618
 0.54
chr11_98772948_98773272 0.14 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 2223
 0.16
chr2_31473064_31473684 0.14 Ass1
 argininosuccinate synthetase 1
 3167
 0.24
chr14_101854215_101854466 0.14 Lmo7
 LIM domain only 7
 13521
 0.26
chr7_122971788_122971939 0.14 Rbbp6
 retinoblastoma binding protein 6, ubiquitin ligase
 945
 0.45
chr11_115246492_115246668 0.14 Gm25837
 predicted gene, 25837
 6698
 0.11
chr17_9663030_9663198 0.14 Pabpc6
 poly(A) binding protein, cytoplasmic 6
 6603
 0.26
chr15_81481395_81481613 0.14 Gm49406
 predicted gene, 49406
 4877
 0.14
chr3_96567003_96567180 0.14 Gm15441
 predicted gene 15441
 290
 0.76
chr4_117125610_117126073 0.14 Btbd19
 BTB (POZ) domain containing 19
 116
 0.86
chr7_113913919_113914070 0.14 Spon1
 spondin 1, (f-spondin) extracellular matrix protein
 147820
 0.04
chr4_152165673_152165840 0.14 Hes2
 hes family bHLH transcription factor 2
 6207
 0.12
chr17_46131243_46131394 0.14 Rsph9
 radial spoke head 9 homolog (Chlamydomonas)
 5477
 0.12
chr7_113935146_113935310 0.14 Gm45615
 predicted gene 45615
 151670
 0.04
chr16_87690191_87690394 0.14 Bach1
 BTB and CNC homology 1, basic leucine zipper transcription factor 1
 8653
 0.22
chr8_77486943_77487275 0.13 0610038B21Rik
 RIKEN cDNA 0610038B21 gene
 29947
 0.14
chr2_174343758_174344168 0.13 Gnas
 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
 349
 0.83
chr8_36291164_36291366 0.13 Lonrf1
 LON peptidase N-terminal domain and ring finger 1
 41749
 0.14
chr15_31259637_31259788 0.13 Dap
 death-associated protein
 8624
 0.16
chr11_43889353_43889625 0.13 Adra1b
 adrenergic receptor, alpha 1b
 11721
 0.25
chr2_167722273_167722608 0.13 A530013C23Rik
 RIKEN cDNA A530013C23 gene
 31259
 0.1
chr13_9052712_9052890 0.13 Gm36264
 predicted gene, 36264
 23650
 0.12
chr17_78714751_78714902 0.13 Strn
 striatin, calmodulin binding protein
 22370
 0.14
chr3_121195173_121195348 0.13 Gm5710
 predicted gene 5710
 14163
 0.14
chr19_46108526_46108716 0.13 Gm50306
 predicted gene, 50306
 16309
 0.11
chr6_48492947_48493147 0.13 Sspo
 SCO-spondin
 733
 0.46
chr4_127034401_127034573 0.13 Gm12940
 predicted gene 12940
 756
 0.49
chr4_109406664_109406986 0.13 Ttc39a
 tetratricopeptide repeat domain 39A
 202
 0.83
chr4_118149267_118149447 0.13 Kdm4a
 lysine (K)-specific demethylase 4A
 2598
 0.22
chr17_25756148_25756299 0.13 Msln
 mesothelin
 1845
 0.11
chr2_135854498_135854679 0.13 Plcb4
 phospholipase C, beta 4
 33106
 0.19
chr2_124902813_124902964 0.13 Slc24a5
 solute carrier family 24, member 5
 165236
 0.03
chr9_44665366_44665550 0.13 Gm3953
 predicted gene 3953
 742
 0.4
chr2_51823121_51823300 0.13 Gm13492
 predicted gene 13492
 4641
 0.25
chr1_186261473_186261624 0.13 Gm37272
 predicted gene, 37272
 79291
 0.09
chr15_97682260_97682559 0.13 Rpap3
 RNA polymerase II associated protein 3
 210
 0.94
chr5_33901574_33901762 0.13 Mir7024
 microRNA 7024
 2697
 0.18
chr11_102755530_102755686 0.13 Adam11
 a disintegrin and metallopeptidase domain 11
 5831
 0.12
chr6_72360016_72360452 0.13 Rnf181
 ring finger protein 181
 833
 0.41
chr17_34733622_34734232 0.13 C4b
 complement component 4B (Chido blood group)
 2172
 0.12
chr16_30755886_30756050 0.13 Gm49754
 predicted gene, 49754
 37287
 0.15
chr9_111148401_111148693 0.13 Lrrfip2
 leucine rich repeat (in FLII) interacting protein 2
 12756
 0.17
chr10_37247416_37247567 0.13 4930543K20Rik
 RIKEN cDNA 4930543K20 gene
 16257
 0.24
chr15_81355699_81355864 0.13 Slc25a17
 solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
 4946
 0.16
chr8_126801964_126802115 0.13 A630001O12Rik
 RIKEN cDNA A630001O12 gene
 37194
 0.15
chr15_81480824_81481310 0.13 Gm49406
 predicted gene, 49406
 5314
 0.14
chr6_121159588_121159765 0.13 Pex26
 peroxisomal biogenesis factor 26
 23991
 0.12
chr3_144109828_144110050 0.12 Gm34078
 predicted gene, 34078
 25815
 0.2
chr13_23285684_23285835 0.12 4933404K08Rik
 RIKEN cDNA 4933404K08 gene
 7409
 0.08
chr3_51252801_51253044 0.12 Elf2
 E74-like factor 2
 7319
 0.13
chr15_85354161_85354332 0.12 Gm23517
 predicted gene, 23517
 2992
 0.27
chr2_173633527_173633866 0.12 Ppp4r1l-ps
 protein phosphatase 4, regulatory subunit 1-like, pseudogene
 4146
 0.21
chr10_85103179_85103555 0.12 Tmem263
 transmembrane protein 263
 624
 0.52
chr6_138128655_138128834 0.12 Mgst1
 microsomal glutathione S-transferase 1
 11572
 0.26
chr16_45377470_45377621 0.12 Cd200
 CD200 antigen
 22767
 0.16
chr7_45150438_45150589 0.12 Aldh16a1
 aldehyde dehydrogenase 16 family, member A1
 1334
 0.13
chr14_68390472_68390641 0.12 Gm31227
 predicted gene, 31227
 71075
 0.11
chr17_56074297_56074510 0.12 Ubxn6
 UBX domain protein 6
 144
 0.9
chr10_69126441_69126619 0.12 Gm24172
 predicted gene, 24172
 6352
 0.17
chr19_8952481_8952632 0.12 Tut1
 terminal uridylyl transferase 1, U6 snRNA-specific
 1291
 0.2
chr13_80885948_80886129 0.12 Arrdc3
 arrestin domain containing 3
 57
 0.89
chr19_46587795_46587964 0.12 Sfxn2
 sideroflexin 2
 3242
 0.18
chr8_60491849_60492091 0.12 Gm10283
 predicted gene 10283
 11228
 0.22
chr1_67189193_67189422 0.12 Gm15668
 predicted gene 15668
 59893
 0.11
chr1_67134415_67135075 0.12 Cps1
 carbamoyl-phosphate synthetase 1
 11719
 0.24
chr4_102966036_102966207 0.12 Sgip1
 SH3-domain GRB2-like (endophilin) interacting protein 1
 3765
 0.19
chr1_39192284_39192607 0.12 Npas2
 neuronal PAS domain protein 2
 1286
 0.45
chr11_119105318_119105491 0.12 Gm11754
 predicted gene 11754
 6021
 0.15
chr18_35277643_35277851 0.12 Gm50146
 predicted gene, 50146
 13718
 0.16
chr1_192061757_192061908 0.12 Traf5
 TNF receptor-associated factor 5
 2670
 0.19
chr2_164161443_164161616 0.12 n-R5s207
 nuclear encoded rRNA 5S 207
 4008
 0.11
chr7_145044142_145044344 0.12 Ccnd1
 cyclin D1
 104318
 0.05
chr11_102749526_102749741 0.12 Adam11
 a disintegrin and metallopeptidase domain 11
 11806
 0.11
chr14_76623735_76623902 0.12 Fkbp1a-ps1
 FK506 binding protein 1a, pseudogene 1
 13046
 0.21
chr4_118247695_118247892 0.12 Ptprf
 protein tyrosine phosphatase, receptor type, F
 11348
 0.17
chr11_116389158_116389441 0.12 Rnf157
 ring finger protein 157
 1894
 0.21
chr10_71857688_71857856 0.12 Gm22937
 predicted gene, 22937
 40264
 0.15
chr3_130660210_130660361 0.12 Etnppl
 ethanolamine phosphate phospholyase
 33765
 0.11
chr2_31496143_31496706 0.12 Ass1
 argininosuccinate synthetase 1
 1348
 0.43
chr12_75851882_75852228 0.12 Syne2
 spectrin repeat containing, nuclear envelope 2
 675
 0.77
chr8_36223220_36223376 0.12 Lonrf1
 LON peptidase N-terminal domain and ring finger 1
 26218
 0.14
chr11_3287201_3287367 0.12 Patz1
 POZ (BTB) and AT hook containing zinc finger 1
 1590
 0.26
chr14_30909356_30909712 0.11 Itih3
 inter-alpha trypsin inhibitor, heavy chain 3
 4595
 0.13
chr19_10187571_10187722 0.11 Mir6993
 microRNA 6993
 3729
 0.12
chr13_111601521_111601690 0.11 Gm10736
 predicted gene 10736
 7994
 0.13
chr8_71377251_71377402 0.11 Nr2f6
 nuclear receptor subfamily 2, group F, member 6
 1536
 0.21
chr17_56273355_56273537 0.11 Ticam1
 toll-like receptor adaptor molecule 1
 3340
 0.12
chr10_7852226_7852377 0.11 Gm24726
 predicted gene, 24726
 3820
 0.16
chr4_95640632_95640805 0.11 Fggy
 FGGY carbohydrate kinase domain containing
 3831
 0.31
chr8_106074831_106075102 0.11 Nfatc3
 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
 15333
 0.1
chr6_120926829_120927234 0.11 Mical3
 microtubule associated monooxygenase, calponin and LIM domain containing 3
 8504
 0.12
chr5_28076176_28076405 0.11 Insig1
 insulin induced gene 1
 1624
 0.34
chr5_107874706_107874894 0.11 Evi5
 ecotropic viral integration site 5
 244
 0.86
chr8_108745611_108745766 0.11 Gm38042
 predicted gene, 38042
 8095
 0.24
chr18_53927118_53927269 0.11 Csnk1g3
 casein kinase 1, gamma 3
 5051
 0.29
chr8_116351879_116352235 0.11 1700018P08Rik
 RIKEN cDNA 1700018P08 gene
 5004
 0.32
chr9_67869712_67870477 0.11 Vps13c
 vacuolar protein sorting 13C
 29682
 0.17
chr7_113228562_113228716 0.11 Arntl
 aryl hydrocarbon receptor nuclear translocator-like
 5984
 0.23
chr15_99096799_99097225 0.11 Dnajc22
 DnaJ heat shock protein family (Hsp40) member C22
 2400
 0.14
chr1_98713946_98714114 0.11 Gm29460
 predicted gene 29460
 50811
 0.17
chr11_98459290_98459441 0.11 Grb7
 growth factor receptor bound protein 7
 5576
 0.1
chr8_124573046_124573209 0.11 Capn9
 calpain 9
 2984
 0.21
chrX_12189621_12189798 0.11 Gm14521
 predicted gene 14521
 9642
 0.24
chr14_65972599_65972894 0.11 Clu
 clusterin
 1443
 0.35
chr17_31319478_31319804 0.11 Slc37a1
 solute carrier family 37 (glycerol-3-phosphate transporter), member 1
 465
 0.76
chr7_99935891_99936042 0.11 Gm18959
 predicted gene, 18959
 9096
 0.12
chr16_4371080_4371246 0.11 Adcy9
 adenylate cyclase 9
 48424
 0.12
chr15_12010383_12010678 0.11 Sub1
 SUB1 homolog, transcriptional regulator
 13547
 0.16
chr10_81408031_81408226 0.11 Nfic
 nuclear factor I/C
 487
 0.49
chr7_63922331_63923024 0.11 Klf13
 Kruppel-like factor 13
 2193
 0.22
chr15_75827912_75828063 0.11 Zc3h3
 zinc finger CCCH type containing 3
 222
 0.88
chr1_188813741_188813916 0.11 Gm25269
 predicted gene, 25269
 53352
 0.16
chr19_16181317_16181503 0.11 E030024N20Rik
 RIKEN cDNA E030024N20 gene
 16605
 0.2
chr15_31252945_31253125 0.11 Dap
 death-associated protein
 15301
 0.15
chr5_53278040_53278387 0.11 Smim20
 small integral membrane protein 20
 1095
 0.48
chr6_72158619_72158820 0.11 Gm38832
 predicted gene, 38832
 4130
 0.17
chr2_31485093_31485244 0.11 Ass1
 argininosuccinate synthetase 1
 12604
 0.18
chr4_104822600_104822778 0.11 C8b
 complement component 8, beta polypeptide
 23481
 0.18
chr2_167959698_167959868 0.11 Ptpn1
 protein tyrosine phosphatase, non-receptor type 1
 8735
 0.17
chr9_116228629_116228809 0.11 Gm31410
 predicted gene, 31410
 9917
 0.19
chr7_24316221_24316527 0.11 Zfp94
 zinc finger protein 94
 208
 0.82
chr7_44589314_44589478 0.11 Gm15396
 predicted gene 15396
 1228
 0.19
chr15_90679035_90679205 0.11 Cpne8
 copine VIII
 251
 0.93
chr1_181465127_181465294 0.11 Gm16539
 predicted gene 16539
 32810
 0.14
chr2_31505484_31505674 0.11 Ass1
 argininosuccinate synthetase 1
 4853
 0.2
chr11_109502246_109502399 0.11 Gm22378
 predicted gene, 22378
 2498
 0.21
chr13_93640508_93640869 0.11 Bhmt
 betaine-homocysteine methyltransferase
 2727
 0.21
chr10_69190805_69191022 0.10 Rhobtb1
 Rho-related BTB domain containing 1
 17639
 0.16
chr2_117018527_117018695 0.10 Gm13981
 predicted gene 13981
 36955
 0.14
chr2_59979903_59980091 0.10 Gm13574
 predicted gene 13574
 12347
 0.19
chr10_42205235_42205454 0.10 Foxo3
 forkhead box O3
 53022
 0.15
chr14_25741793_25741944 0.10 Zcchc24
 zinc finger, CCHC domain containing 24
 22076
 0.13
chr4_118476510_118476661 0.10 Tie1
 tyrosine kinase with immunoglobulin-like and EGF-like domains 1
 13170
 0.1
chr19_47305501_47305661 0.10 Sh3pxd2a
 SH3 and PX domains 2A
 9170
 0.17
chr15_78852145_78852296 0.10 Lgals2
 lectin, galactose-binding, soluble 2
 3309
 0.11

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.1 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.2 GO:0006563 L-serine metabolic process(GO:0006563)
0.0 0.1 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0003099 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.1 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0060137 maternal process involved in parturition(GO:0060137)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.0 0.1 GO:1904504 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0048669 collateral sprouting in absence of injury(GO:0048669)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.1 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.0 GO:1902996 neurofibrillary tangle assembly(GO:1902988) regulation of neurofibrillary tangle assembly(GO:1902996)
0.0 0.1 GO:0010963 regulation of L-arginine import(GO:0010963)
0.0 0.0 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0061043 regulation of vascular wound healing(GO:0061043)
0.0 0.1 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.0 0.1 GO:1903525 regulation of membrane tubulation(GO:1903525)
0.0 0.1 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0010310 regulation of hydrogen peroxide metabolic process(GO:0010310)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.1 GO:0034756 regulation of iron ion transport(GO:0034756)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.0 GO:0097460 ferrous iron import into cell(GO:0097460)
0.0 0.0 GO:0003223 ventricular compact myocardium morphogenesis(GO:0003223)
0.0 0.1 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:2000619 negative regulation of histone H4-K16 acetylation(GO:2000619)
0.0 0.0 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:1904469 positive regulation of tumor necrosis factor secretion(GO:1904469)
0.0 0.1 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.0 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.0 0.0 GO:0030242 pexophagy(GO:0030242)
0.0 0.0 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.0 GO:0045472 response to ether(GO:0045472)
0.0 0.0 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0 0.0 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.0 0.0 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.0 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.1 GO:0019401 alditol biosynthetic process(GO:0019401)
0.0 0.0 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.0 GO:0021943 formation of radial glial scaffolds(GO:0021943)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283)
0.0 0.0 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.1 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.0 GO:0021699 cerebellar cortex maturation(GO:0021699)
0.0 0.0 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.0 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.0 GO:0008228 opsonization(GO:0008228)
0.0 0.0 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.0 GO:0051081 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793) regulation of ribonucleoprotein complex localization(GO:2000197)
0.0 0.0 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0 0.0 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.0 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.0 GO:1903275 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278)
0.0 0.0 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:1903798 regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0 0.1 GO:1990845 diet induced thermogenesis(GO:0002024) adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.0 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.1 GO:0051775 response to redox state(GO:0051775)
0.0 0.0 GO:0030091 protein repair(GO:0030091)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:1990357 terminal web(GO:1990357)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0097451 glial limiting end-foot(GO:0097451)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0042627 chylomicron(GO:0042627)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.0 GO:0071942 XPC complex(GO:0071942)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.2 GO:0043731 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.0 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0008430 selenium binding(GO:0008430)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.0 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.0 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.1 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.0 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.0 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0031779 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0 0.0 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.0 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.0 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0 0.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.0 GO:0035276 ethanol binding(GO:0035276)
0.0 0.0 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.0 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.0 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.0 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.0 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.0 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway