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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Tcf21_Msc

Z-value: 1.61

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Transcription factors associated with Tcf21_Msc

Gene Symbol	Gene ID	Gene Info
Tcf21 Ensembl NCBI MGI UniProt	ENSMUSG00000045680.7	transcription factor 21
Msc Ensembl NCBI MGI UniProt	ENSMUSG00000025930.5	musculin

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr10_22820121_22820272	Tcf21	22	0.972710	0.26	6.1e-01	Click!
chr10_22843285_22843469	Tcf21	23203	0.157237	-0.07	8.9e-01	Click!
chr10_22875325_22875476	Tcf21	55226	0.108644	-0.02	9.7e-01	Click!

Activity of the Tcf21_Msc motif across conditions

Conditions sorted by the z-value of the Tcf21_Msc motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr7_121802332_121802546	1.11	Gm44740	predicted gene 44740	36626	0.13
chr14_30173289_30173526	1.10	Cacna1d	calcium channel, voltage-dependent, L type, alpha 1D subunit	1984	0.35
chr13_58962693_58962856	0.87	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2	91039	0.06
chr5_30534594_30534940	0.84	Gm42765	predicted gene 42765	5267	0.14
chr9_74893395_74893777	0.80	Onecut1	one cut domain, family member 1	27102	0.13
chr11_6021664_6021840	0.72	Camk2b	calcium/calmodulin-dependent protein kinase II, beta	21304	0.15
chr19_10599348_10599499	0.72	Tkfc	triokinase, FMN cyclase	4835	0.1
chr9_74884431_74884582	0.70	Onecut1	one cut domain, family member 1	18022	0.15
chr6_149333094_149333245	0.68	Resf1	retroelement silencing factor 1	7711	0.14
chr10_95434881_95435051	0.68	5730420D15Rik	RIKEN cDNA 5730420D15 gene	17591	0.11
chr18_84376797_84376986	0.66	Gm37216	predicted gene, 37216	745	0.73
chr6_93669779_93669930	0.63	Gm7812	predicted gene 7812	19629	0.25
chr11_16821774_16821942	0.63	Egfros	epidermal growth factor receptor, opposite strand	8844	0.22
chr15_39116967_39117141	0.60	Dcaf13	DDB1 and CUL4 associated factor 13	4189	0.15
chr5_43310353_43310569	0.59	Gm43020	predicted gene 43020	44798	0.11
chr8_4839167_4839331	0.59	Gm44961	predicted gene 44961	18019	0.12
chr8_3211565_3211796	0.57	Insr	insulin receptor	18963	0.18
chr2_90668038_90668212	0.57	Nup160	nucleoporin 160	9090	0.2
chr11_76827089_76827249	0.56	Cpd	carboxypeptidase D	18343	0.19
chr11_16879295_16879446	0.56	Egfr	epidermal growth factor receptor	1220	0.5
chr13_80890166_80890317	0.56	Arrdc3	arrestin domain containing 3	137	0.95
chr11_120817967_120818292	0.56	Fasn	fatty acid synthase	2674	0.13
chr3_152091714_152091865	0.53	Gipc2	GIPC PDZ domain containing family, member 2	11065	0.14
chr11_16879568_16879719	0.53	Egfr	epidermal growth factor receptor	1493	0.43
chr8_46385009_46385281	0.53	Gm45253	predicted gene 45253	743	0.6
chr12_104087488_104087669	0.53	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	6929	0.1
chr11_120814981_120815132	0.52	Fasn	fatty acid synthase	399	0.71
chr2_167292312_167292496	0.52	Gm11473	predicted gene 11473	10627	0.16
chr4_141955631_141955810	0.52	Fhad1	forkhead-associated (FHA) phosphopeptide binding domain 1	1526	0.3
chr11_16879987_16880147	0.51	Egfr	epidermal growth factor receptor	1917	0.36
chr4_117831574_117831756	0.51	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	2841	0.16
chr8_120046709_120046884	0.51	Gm15684	predicted gene 15684	1509	0.32
chr6_117577757_117577908	0.51	Gm9946	predicted gene 9946	10160	0.2
chr9_116136919_116137123	0.51	Tgfbr2	transforming growth factor, beta receptor II	38244	0.15
chr11_16828832_16828991	0.49	Egfros	epidermal growth factor receptor, opposite strand	1791	0.4
chrX_42602450_42602620	0.47	Sh2d1a	SH2 domain containing 1A	75950	0.1
chr12_104084479_104084838	0.47	Serpina4-ps1	serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1	4009	0.12
chr15_87233626_87233777	0.46	A930027H12Rik	RIKEN cDNA A930027H12 gene	9849	0.25
chr11_52257389_52257568	0.45	Tcf7	transcription factor 7, T cell specific	17399	0.11
chr3_69362162_69362601	0.45	Gm17212	predicted gene 17212	26621	0.16
chr1_131770748_131770959	0.45	Slc26a9	solute carrier family 26, member 9	20362	0.14
chr14_9608900_9609103	0.45	Gm48371	predicted gene, 48371	139446	0.05
chr2_156571655_156571819	0.44	Gm14168	predicted gene 14168	55	0.96
chr14_32708910_32709089	0.44	Gm28651	predicted gene 28651	22441	0.16
chr18_6464158_6464366	0.44	Epc1	enhancer of polycomb homolog 1	22368	0.15
chr17_86446823_86447020	0.44	Prkce	protein kinase C, epsilon	43641	0.17
chr10_111314954_111315105	0.44	Bbs10	Bardet-Biedl syndrome 10 (human)	16350	0.18
chr5_125524109_125525122	0.44	Tmem132b	transmembrane protein 132B	7159	0.16
chr7_79308613_79308815	0.43	Gm39041	predicted gene, 39041	9689	0.14
chr5_125492454_125492640	0.43	Gm27551	predicted gene, 27551	13170	0.13
chr9_31610718_31610869	0.42	Gm18820	predicted gene, 18820	32977	0.14
chr19_47660118_47660275	0.42	Col17a1	collagen, type XVII, alpha 1	10601	0.12
chr11_120819185_120819682	0.42	Fasn	fatty acid synthase	3978	0.11
chr19_11977402_11977711	0.41	Osbp	oxysterol binding protein	11615	0.09
chr1_36316895_36317108	0.41	Arid5a	AT rich interactive domain 5A (MRF1-like)	26	0.97
chr18_84376572_84376752	0.41	Gm37216	predicted gene, 37216	516	0.84
chr17_70004735_70004886	0.41	Dlgap1	DLG associated protein 1	35389	0.2
chr10_87880307_87880601	0.41	Igf1os	insulin-like growth factor 1, opposite strand	17073	0.18
chr8_34460252_34460438	0.41	Gm45349	predicted gene 45349	12650	0.18
chr4_10854377_10854556	0.40	Gm12919	predicted gene 12919	623	0.61
chr1_138967552_138967703	0.40	Dennd1b	DENN/MADD domain containing 1B	93	0.91
chr5_139358617_139359046	0.40	Cyp2w1	cytochrome P450, family 2, subfamily w, polypeptide 1	4255	0.13
chr5_75063247_75063407	0.40	Gsx2	GS homeobox 2	12274	0.11
chr16_56063021_56063172	0.39	Gm24047	predicted gene, 24047	7467	0.12
chr9_74891211_74891440	0.39	Onecut1	one cut domain, family member 1	24841	0.14
chr7_127973702_127973919	0.39	Fus	fused in sarcoma	333	0.72
chr18_65989569_65989860	0.38	Lman1	lectin, mannose-binding, 1	3946	0.15
chr13_112331307_112331468	0.38	Ankrd55	ankyrin repeat domain 55	12933	0.17
chr12_41500503_41500654	0.37	Lrrn3	leucine rich repeat protein 3, neuronal	14147	0.22
chr11_120811259_120811452	0.37	Fasn	fatty acid synthase	1654	0.19
chr18_61357667_61357827	0.37	Gm25301	predicted gene, 25301	40066	0.1
chr18_65968667_65968818	0.37	Cplx4	complexin 4	1060	0.37
chr9_55278709_55278860	0.36	Nrg4	neuregulin 4	4788	0.2
chr7_15939282_15939433	0.36	Snord23	small nucleolar RNA, C/D box 23	487	0.65
chr5_33465411_33465562	0.36	Gm43851	predicted gene 43851	28022	0.15
chr5_125484345_125484496	0.36	Gm27551	predicted gene, 27551	5043	0.14
chrX_111626357_111626522	0.36	Gm7340	predicted gene 7340	54740	0.14
chr13_58192282_58192443	0.35	Gm48357	predicted gene, 48357	1044	0.37
chr9_98418368_98418712	0.35	Rbp1	retinol binding protein 1, cellular	4421	0.24
chr8_105256295_105256446	0.35	B3gnt9	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9	1217	0.21
chr10_91261198_91261441	0.35	Gm18705	predicted gene, 18705	1975	0.31
chrX_56970947_56971107	0.35	Adgrg4	adhesion G protein-coupled receptor G4	2907	0.31
chr4_44784029_44784206	0.35	Zcchc7	zinc finger, CCHC domain containing 7	23673	0.15
chr9_35103547_35103698	0.35	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	3045	0.2
chr9_34258652_34258813	0.35	Gm27161	predicted gene 27161	58504	0.15
chr5_125523118_125523269	0.35	Aacs	acetoacetyl-CoA synthetase	7950	0.16
chr11_16808080_16808304	0.34	Egfros	epidermal growth factor receptor, opposite strand	22510	0.19
chr5_144416866_144417038	0.34	Gm15709	predicted gene 15709	10350	0.2
chr11_118451300_118451612	0.34	Gm11747	predicted gene 11747	3539	0.16
chr11_86769997_86770170	0.34	Cltc	clathrin, heavy polypeptide (Hc)	12518	0.19
chr13_48916144_48916308	0.34	Phf2	PHD finger protein 2	45107	0.13
chr1_92683263_92683419	0.34	Gm29483	predicted gene 29483	33861	0.09
chr10_80668723_80668916	0.33	Mknk2	MAP kinase-interacting serine/threonine kinase 2	3157	0.11
chr11_60201760_60201955	0.33	Srebf1	sterol regulatory element binding transcription factor 1	358	0.51
chr1_50806470_50806812	0.32	Gm28321	predicted gene 28321	8734	0.28
chrX_77601507_77601673	0.32	Gm23121	predicted gene, 23121	22103	0.2
chr17_10093572_10093736	0.32	Qk	quaking	119920	0.06
chr8_80289362_80289553	0.32	Gm45430	predicted gene 45430	94258	0.08
chr10_8818073_8818257	0.32	Gm25410	predicted gene, 25410	5982	0.21
chr14_63326787_63326957	0.32	Gm5463	predicted gene 5463	2348	0.25
chr7_38162494_38162645	0.32	Gm22203	predicted gene, 22203	14102	0.13
chr4_150660019_150660333	0.32	Slc45a1	solute carrier family 45, member 1	8002	0.19
chr17_43270317_43270505	0.32	Adgrf1	adhesion G protein-coupled receptor F1	82	0.98
chr4_97765098_97765412	0.32	Nfia	nuclear factor I/A	7479	0.2
chr12_30372401_30372579	0.32	Sntg2	syntrophin, gamma 2	775	0.73
chr4_129216612_129216763	0.32	Yars	tyrosyl-tRNA synthetase	2925	0.17
chr12_112125883_112126333	0.32	Mir203	microRNA 203	4772	0.13
chr4_57070625_57070924	0.32	Epb41l4b	erythrocyte membrane protein band 4.1 like 4b	215	0.95
chr11_16878966_16879155	0.32	Egfr	epidermal growth factor receptor	910	0.61
chr10_117884880_117885031	0.31	Gm32552	predicted gene, 32552	18240	0.14
chr8_105090981_105091315	0.31	Ces3b	carboxylesterase 3B	2529	0.16
chr11_6158649_6158802	0.31	Rps15a-ps6	ribosomal protein S15A, pseudogene 6	14311	0.13
chr1_174931061_174931246	0.30	Grem2	gremlin 2, DAN family BMP antagonist	9334	0.3
chr6_67300933_67301090	0.30	Serbp1	serpine1 mRNA binding protein 1	29132	0.12
chr1_151686797_151686981	0.30	Fam129a	family with sequence similarity 129, member A	9722	0.22
chr5_149616281_149616432	0.30	Hsph1	heat shock 105kDa/110kDa protein 1	2817	0.21
chr2_58768981_58769132	0.30	Upp2	uridine phosphorylase 2	3731	0.25
chr2_84995821_84996178	0.30	Prg3	proteoglycan 3	7784	0.12
chr6_119643983_119644181	0.30	Erc1	ELKS/RAB6-interacting/CAST family member 1	21977	0.22
chr15_59454105_59454285	0.30	Nsmce2	NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase	79908	0.08
chr2_58771897_58772048	0.30	Upp2	uridine phosphorylase 2	6647	0.22
chr15_55634841_55635006	0.30	Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein	13471	0.25
chr11_98766772_98767040	0.30	Nr1d1	nuclear receptor subfamily 1, group D, member 1	3520	0.12
chr15_27800508_27800681	0.30	Trio	triple functional domain (PTPRF interacting)	11956	0.22
chr15_3524128_3524292	0.30	Ghr	growth hormone receptor	52566	0.15
chr2_166834206_166834387	0.30	Arfgef2	ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)	6639	0.19
chr15_100112289_100112692	0.30	4930478M13Rik	RIKEN cDNA 4930478M13 gene	4329	0.17
chr2_158317109_158317280	0.29	Lbp	lipopolysaccharide binding protein	2988	0.15
chr13_43530948_43531160	0.29	Gm32939	predicted gene, 32939	834	0.53
chr11_95370162_95370363	0.29	Fam117a	family with sequence similarity 117, member A	5205	0.13
chr5_138863743_138864096	0.29	Gm5294	predicted gene 5294	43839	0.13
chr18_38016662_38016813	0.29	Gm30093	predicted gene, 30093	6792	0.12
chr16_30664084_30664254	0.29	Fam43a	family with sequence similarity 43, member A	64446	0.1
chr4_133561732_133562055	0.29	Gm23158	predicted gene, 23158	2944	0.13
chr11_113667224_113667404	0.29	Cog1	component of oligomeric golgi complex 1	8031	0.12
chr15_81249111_81249532	0.29	8430426J06Rik	RIKEN cDNA 8430426J06 gene	1353	0.36
chr13_47039268_47039419	0.29	Tpmt	thiopurine methyltransferase	2238	0.17
chr2_131869043_131869244	0.28	Erv3	endogenous retroviral sequence 3	9396	0.12
chr9_83951310_83951505	0.28	Bckdhb	branched chain ketoacid dehydrogenase E1, beta polypeptide	2626	0.23
chr1_90161712_90161886	0.28	4930434B07Rik	RIKEN cDNA 4930434B07 gene	8171	0.18
chr6_90592647_90592924	0.28	Aldh1l1	aldehyde dehydrogenase 1 family, member L1	3435	0.17
chr8_84351080_84351276	0.28	Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	12539	0.13
chr11_16771754_16772101	0.28	Egfr	epidermal growth factor receptor	19697	0.18
chr1_162892140_162892544	0.28	Fmo2	flavin containing monooxygenase 2	5827	0.19
chr10_68102616_68102812	0.28	Arid5b	AT rich interactive domain 5B (MRF1-like)	33912	0.17
chr1_153699524_153699675	0.28	Gm29529	predicted gene 29529	6943	0.12
chr4_150080461_150080620	0.28	Gpr157	G protein-coupled receptor 157	6825	0.11
chr9_74793041_74793363	0.28	Gm22315	predicted gene, 22315	11132	0.18
chr3_18482157_18482333	0.28	4930433B08Rik	RIKEN cDNA 4930433B08 gene	1768	0.37
chr13_38318516_38318698	0.27	Gm47990	predicted gene, 47990	1919	0.29
chr5_102011072_102011265	0.27	Wdfy3	WD repeat and FYVE domain containing 3	29610	0.16
chr7_115855107_115855272	0.27	Sox6	SRY (sex determining region Y)-box 6	4663	0.32
chr11_106412764_106412932	0.27	Icam2	intercellular adhesion molecule 2	24773	0.12
chr15_59319862_59320035	0.27	Sqle	squalene epoxidase	4841	0.18
chr15_59004329_59004523	0.27	4930544F09Rik	RIKEN cDNA 4930544F09 gene	20290	0.16
chr15_98738867_98739043	0.27	Fkbp11	FK506 binding protein 11	10757	0.09
chr7_67636165_67636335	0.27	Gm45100	predicted gene 45100	1515	0.31
chr1_41557400_41557596	0.27	Gm28634	predicted gene 28634	27955	0.26
chr1_87763908_87764120	0.27	Atg16l1	autophagy related 16-like 1 (S. cerevisiae)	2887	0.18
chr12_32707351_32707528	0.27	Gm18726	predicted gene, 18726	2722	0.31
chr11_118748971_118749122	0.27	Rbfox3	RNA binding protein, fox-1 homolog (C. elegans) 3	11995	0.22
chr14_74924136_74924288	0.27	Gm10847	predicted gene 10847	2233	0.32
chr8_114128875_114129050	0.27	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	4595	0.32
chr12_103687063_103687254	0.27	Serpina1f	serine (or cysteine) peptidase inhibitor, clade A, member 1F	7508	0.1
chr11_107850492_107850643	0.27	Gm27595	predicted gene, 27595	1178	0.49
chr19_41482156_41482948	0.27	Lcor	ligand dependent nuclear receptor corepressor	85	0.98
chr5_51144711_51144875	0.27	Gm44377	predicted gene, 44377	78881	0.1
chr8_25256824_25256983	0.27	Tacc1	transforming, acidic coiled-coil containing protein 1	315	0.9
chr19_20723027_20723214	0.26	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	4442	0.3
chr16_32698159_32698320	0.26	Tnk2	tyrosine kinase, non-receptor, 2	17425	0.13
chr9_108401502_108401859	0.26	1700102P08Rik	RIKEN cDNA 1700102P08 gene	8846	0.07
chr7_26309085_26309252	0.26	Gm42375	predicted gene, 42375	1882	0.22
chr11_116057344_116057497	0.26	Unk	unkempt family zinc finger	1522	0.24
chr10_67696602_67696753	0.26	Gm47574	predicted gene, 47574	11161	0.16
chr8_123661291_123661442	0.26	Rhou	ras homolog family member U	7437	0.05
chrX_164521600_164521775	0.26	Asb9	ankyrin repeat and SOCS box-containing 9	15360	0.22
chr2_173682841_173683018	0.26	Mir6340	microRNA 6340	18219	0.13
chrX_36766114_36766265	0.26	Gm23613	predicted gene, 23613	10430	0.14
chr11_84205927_84206078	0.26	Acaca	acetyl-Coenzyme A carboxylase alpha	10564	0.18
chr1_41551537_41551723	0.26	Gm28634	predicted gene 28634	22087	0.28
chr17_35784068_35784237	0.26	4833427F10Rik	RIKEN cDNA 4833427F10 gene	11702	0.08
chr10_93431595_93431770	0.26	Mir7688	microRNA 7688	1425	0.36
chr15_58983651_58983950	0.26	4930544F09Rik	RIKEN cDNA 4930544F09 gene	336	0.87
chr18_12743258_12743476	0.26	Gm7599	predicted gene 7599	108	0.94
chr12_79905913_79906084	0.25	9430078K24Rik	RIKEN cDNA 9430078K24 gene	18735	0.2
chr3_10370926_10371217	0.25	Chmp4c	charged multivesicular body protein 4C	4113	0.15
chr5_137052026_137052177	0.25	Ap1s1	adaptor protein complex AP-1, sigma 1	5966	0.11
chr3_11357506_11357684	0.25	Gm22547	predicted gene, 22547	203258	0.03
chr3_18105527_18105678	0.25	Gm23726	predicted gene, 23726	36276	0.16
chr5_33720967_33721166	0.25	Fgfr3	fibroblast growth factor receptor 3	608	0.58
chr4_140283535_140283688	0.25	Igsf21	immunoglobulin superfamily, member 21	36827	0.14
chr14_67917259_67917426	0.25	Dock5	dedicator of cytokinesis 5	16090	0.22
chr15_81798335_81798552	0.25	Tef	thyrotroph embryonic factor	3978	0.12
chr5_97079576_97079732	0.25	Paqr3	progestin and adipoQ receptor family member III	18117	0.16
chr13_44306877_44307103	0.25	Gm29676	predicted gene, 29676	26541	0.17
chr12_69813103_69813302	0.25	Map4k5	mitogen-activated protein kinase kinase kinase kinase 5	5251	0.14
chr4_139454119_139454298	0.25	Ubr4	ubiquitin protein ligase E3 component n-recognin 4	9051	0.18
chr2_152359606_152359999	0.25	Gm14165	predicted gene 14165	6187	0.1
chr1_193928644_193928965	0.25	Gm21362	predicted gene, 21362	61795	0.15
chr3_115815549_115815774	0.25	Dph5	diphthamide biosynthesis 5	72176	0.07

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf21_Msc

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.7	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1	0.4	GO:1902488	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1	0.4	GO:0086046	membrane depolarization during SA node cell action potential(GO:0086046)
0.1	0.3	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1	0.4	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1	0.3	GO:0015817	histidine transport(GO:0015817)
0.1	0.3	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.1	0.2	GO:1903690	negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1	0.2	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.2	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1	0.2	GO:0032474	otolith morphogenesis(GO:0032474)
0.1	0.2	GO:0010446	response to alkaline pH(GO:0010446)
0.1	0.1	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.1	0.2	GO:0061144	alveolar secondary septum development(GO:0061144)
0.1	0.3	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.1	0.2	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.1	0.2	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.1	0.1	GO:0045608	negative regulation of auditory receptor cell differentiation(GO:0045608)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0009732	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0032485	regulation of Ral protein signal transduction(GO:0032485)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.4	GO:0051547	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.1	GO:1901187	regulation of ephrin receptor signaling pathway(GO:1901187)
0.0	0.2	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.1	GO:2000359	regulation of binding of sperm to zona pellucida(GO:2000359)
0.0	0.2	GO:0021590	cerebellum maturation(GO:0021590)
0.0	0.1	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.1	GO:1902083	negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0	0.2	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:1903334	positive regulation of protein folding(GO:1903334)
0.0	0.1	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.0	0.1	GO:0060528	secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.3	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.3	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.1	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.0	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.2	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.3	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.1	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.0	0.1	GO:0001796	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.0	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.2	GO:0009256	10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0	0.1	GO:0006701	progesterone biosynthetic process(GO:0006701)
0.0	0.1	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0060510	Type II pneumocyte differentiation(GO:0060510)
0.0	0.1	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.2	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.1	GO:0010387	COP9 signalosome assembly(GO:0010387)
0.0	0.2	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.0	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.2	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.0	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0060509	Type I pneumocyte differentiation(GO:0060509)
0.0	0.1	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.6	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.1	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.1	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.1	GO:0060448	dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0	0.1	GO:0014016	neuroblast differentiation(GO:0014016)
0.0	0.1	GO:2000574	regulation of microtubule motor activity(GO:2000574)
0.0	0.1	GO:1903238	positive regulation of leukocyte tethering or rolling(GO:1903238)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.1	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0015959	diadenosine polyphosphate metabolic process(GO:0015959)
0.0	0.1	GO:2000609	regulation of thyroid hormone generation(GO:2000609)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.1	GO:2001206	positive regulation of osteoclast development(GO:2001206)
0.0	0.1	GO:0090135	actin filament branching(GO:0090135)
0.0	0.1	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.0	0.1	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:1900044	regulation of protein K63-linked ubiquitination(GO:1900044)
0.0	0.1	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.0	0.2	GO:0033169	histone H3-K9 demethylation(GO:0033169)
0.0	0.1	GO:0050882	voluntary musculoskeletal movement(GO:0050882)
0.0	0.0	GO:0034395	regulation of transcription from RNA polymerase II promoter in response to iron(GO:0034395)
0.0	0.2	GO:0070417	cellular response to cold(GO:0070417)
0.0	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:1905216	positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0	0.1	GO:1903753	negative regulation of p38MAPK cascade(GO:1903753)
0.0	0.2	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.0	0.1	GO:0035977	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0	0.1	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.0	0.0	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.1	GO:0042126	nitrate metabolic process(GO:0042126)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:1900736	regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.0	0.1	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.1	GO:0070488	neutrophil aggregation(GO:0070488)
0.0	0.0	GO:0045764	positive regulation of cellular amino acid metabolic process(GO:0045764)
0.0	0.0	GO:0061184	positive regulation of dermatome development(GO:0061184)
0.0	0.0	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0000480	endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0009249	protein lipoylation(GO:0009249)
0.0	0.2	GO:0042759	long-chain fatty acid biosynthetic process(GO:0042759)
0.0	0.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.1	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:0061153	trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.0	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0019660	fermentation(GO:0006113) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.0	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.1	GO:0051305	chromosome movement towards spindle pole(GO:0051305)
0.0	0.0	GO:0006003	fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0	0.0	GO:0060988	lipid tube assembly(GO:0060988)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.1	GO:0031547	brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0	0.0	GO:0072235	distal convoluted tubule development(GO:0072025) DCT cell differentiation(GO:0072069) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235) metanephric DCT cell differentiation(GO:0072240)
0.0	0.0	GO:0010482	epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0	0.1	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.0	0.0	GO:0033121	regulation of purine nucleotide catabolic process(GO:0033121)
0.0	0.0	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.0	0.1	GO:0042795	snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.2	GO:0033147	negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0	0.1	GO:0007042	lysosomal lumen acidification(GO:0007042)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.0	GO:1900238	positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:1901723	negative regulation of cell proliferation involved in kidney development(GO:1901723)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.0	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.0	GO:0046391	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.0	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.1	GO:0046882	negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0	0.2	GO:0045898	regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0	0.1	GO:0055091	phospholipid homeostasis(GO:0055091)
0.0	0.0	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.0	GO:0034182	regulation of maintenance of sister chromatid cohesion(GO:0034091) regulation of maintenance of mitotic sister chromatid cohesion(GO:0034182)
0.0	0.1	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.0	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.0	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.0	0.1	GO:0045908	negative regulation of vasodilation(GO:0045908)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.1	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.0	GO:0038086	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0	0.0	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.0	0.1	GO:0033227	dsRNA transport(GO:0033227)
0.0	0.3	GO:2000758	positive regulation of peptidyl-lysine acetylation(GO:2000758)
0.0	0.0	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0034162	toll-like receptor 9 signaling pathway(GO:0034162)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.0	GO:0070947	neutrophil mediated killing of fungus(GO:0070947)
0.0	0.0	GO:0035799	ureter maturation(GO:0035799)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.0	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.2	GO:0018126	protein hydroxylation(GO:0018126)
0.0	0.0	GO:0061343	cell adhesion involved in heart morphogenesis(GO:0061343)
0.0	0.0	GO:0072718	response to cisplatin(GO:0072718)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0031339	negative regulation of vesicle fusion(GO:0031339)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.2	GO:0051457	maintenance of protein location in nucleus(GO:0051457)
0.0	0.0	GO:0019065	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.1	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.0	GO:0072050	S-shaped body morphogenesis(GO:0072050)
0.0	0.0	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.0	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.2	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.0	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0	0.0	GO:0006848	pyruvate transport(GO:0006848)
0.0	0.1	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.0	GO:0061346	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.0	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.0	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.0	GO:0070885	negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0	0.0	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.0	GO:0002840	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0032060	bleb assembly(GO:0032060)
0.0	0.0	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.0	GO:0061438	renal system vasculature morphogenesis(GO:0061438) kidney vasculature morphogenesis(GO:0061439)
0.0	0.1	GO:0060040	retinal bipolar neuron differentiation(GO:0060040)
0.0	0.2	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.0	GO:0051610	serotonin uptake(GO:0051610)
0.0	0.0	GO:1900125	regulation of hyaluronan biosynthetic process(GO:1900125)
0.0	0.0	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.0	GO:0030070	insulin processing(GO:0030070)
0.0	0.1	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.0	0.1	GO:0048671	negative regulation of collateral sprouting(GO:0048671)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:1904752	vascular associated smooth muscle cell migration(GO:1904738) regulation of vascular associated smooth muscle cell migration(GO:1904752)
0.0	0.1	GO:0060546	negative regulation of necroptotic process(GO:0060546)
0.0	0.1	GO:0051481	negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0	0.0	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.0	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0031296	B cell costimulation(GO:0031296)
0.0	0.0	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.0	GO:0070175	positive regulation of enamel mineralization(GO:0070175)
0.0	0.0	GO:0048388	endosomal lumen acidification(GO:0048388)
0.0	0.0	GO:0002408	myeloid dendritic cell chemotaxis(GO:0002408)
0.0	0.0	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.1	GO:0033262	regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0	0.0	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.0	GO:0021631	optic nerve morphogenesis(GO:0021631)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.0	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.0	GO:0086045	membrane depolarization during AV node cell action potential(GO:0086045)
0.0	0.0	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.0	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0034196	acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0	0.0	GO:0060544	regulation of necroptotic process(GO:0060544)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.1	GO:0090085	regulation of protein deubiquitination(GO:0090085)
0.0	0.1	GO:2000637	positive regulation of gene silencing by miRNA(GO:2000637)
0.0	0.0	GO:0042699	follicle-stimulating hormone signaling pathway(GO:0042699)
0.0	0.1	GO:2001275	positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0	0.0	GO:0033566	gamma-tubulin complex localization(GO:0033566)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0046719	regulation by virus of viral protein levels in host cell(GO:0046719)
0.0	0.0	GO:0090080	positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0	0.0	GO:0009957	epidermal cell fate specification(GO:0009957)
0.0	0.0	GO:0060084	synaptic transmission involved in micturition(GO:0060084)
0.0	0.0	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:2000320	negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0035867	alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1	0.7	GO:0042587	glycogen granule(GO:0042587)
0.1	0.3	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1	0.4	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.2	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.1	0.4	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.2	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.3	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.1	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0071817	MMXD complex(GO:0071817)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.0	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0001650	fibrillar center(GO:0001650)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.1	GO:0042629	mast cell granule(GO:0042629)
0.0	0.1	GO:0032280	symmetric synapse(GO:0032280)
0.0	0.2	GO:0071564	npBAF complex(GO:0071564)
0.0	0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	0.0	GO:0097454	Schwann cell microvillus(GO:0097454)
0.0	0.5	GO:0005891	voltage-gated calcium channel complex(GO:0005891)
0.0	0.1	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.1	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.1	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.0	0.1	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.0	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.0	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.0	GO:0031264	death-inducing signaling complex(GO:0031264)
0.0	0.2	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.2	GO:0001741	XY body(GO:0001741)
0.0	0.1	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.1	GO:0042583	chromaffin granule(GO:0042583)
0.0	0.0	GO:0042824	MHC class I peptide loading complex(GO:0042824)
0.0	0.2	GO:0034706	sodium channel complex(GO:0034706)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0031417	NatC complex(GO:0031417)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.0	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.1	GO:0072357	PTW/PP1 phosphatase complex(GO:0072357)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.0	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0030312	external encapsulating structure(GO:0030312)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.1	GO:0000778	condensed nuclear chromosome kinetochore(GO:0000778)
0.0	0.0	GO:0033648	host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0	0.1	GO:0072669	tRNA-splicing ligase complex(GO:0072669)
0.0	0.1	GO:0098645	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0001520	outer dense fiber(GO:0001520)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.1	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.1	GO:0030132	clathrin coat of coated pit(GO:0030132)
0.0	0.0	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.0	0.1	GO:0031314	extrinsic component of mitochondrial inner membrane(GO:0031314)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.6	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.4	GO:0086007	voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.1	0.2	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.2	GO:0097109	neuroligin family protein binding(GO:0097109)
0.1	0.3	GO:0004897	ciliary neurotrophic factor receptor activity(GO:0004897)
0.1	0.4	GO:0001515	opioid peptide activity(GO:0001515)
0.1	0.2	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1	0.2	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.6	GO:0004312	fatty acid synthase activity(GO:0004312)
0.1	0.3	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.1	0.5	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.3	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.8	GO:0031690	adrenergic receptor binding(GO:0031690)
0.0	0.2	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.2	GO:0035276	ethanol binding(GO:0035276)
0.0	0.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0050510	N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0	0.4	GO:0019841	retinol binding(GO:0019841)
0.0	0.1	GO:0019153	protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.0	GO:0005290	L-histidine transmembrane transporter activity(GO:0005290)
0.0	0.3	GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.1	GO:0032190	acrosin binding(GO:0032190)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.3	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.2	GO:0005078	MAP-kinase scaffold activity(GO:0005078)
0.0	0.2	GO:0005024	transforming growth factor beta-activated receptor activity(GO:0005024)
0.0	0.1	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0	0.1	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.0	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0002060	purine nucleobase binding(GO:0002060)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.2	GO:0005225	volume-sensitive anion channel activity(GO:0005225)
0.0	0.1	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.1	GO:0061629	RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0	0.1	GO:0070538	oleic acid binding(GO:0070538)
0.0	0.2	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.1	GO:0008309	double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0	0.2	GO:0004445	inositol-polyphosphate 5-phosphatase activity(GO:0004445)
0.0	0.1	GO:0005030	neurotrophin receptor activity(GO:0005030)
0.0	0.1	GO:0036122	BMP binding(GO:0036122)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.1	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.4	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.2	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.2	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0	0.2	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.0	GO:0043812	phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0	0.1	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.0	0.1	GO:0050145	nucleoside phosphate kinase activity(GO:0050145)
0.0	0.1	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.0	0.0	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.1	GO:0004515	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.0	0.1	GO:0015280	ligand-gated sodium channel activity(GO:0015280)
0.0	0.1	GO:0035877	death effector domain binding(GO:0035877)
0.0	0.1	GO:0055056	D-glucose transmembrane transporter activity(GO:0055056)
0.0	0.3	GO:0046965	retinoid X receptor binding(GO:0046965)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0051032	nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0	0.1	GO:0043559	insulin binding(GO:0043559)
0.0	0.0	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.0	GO:0004605	phosphatidate cytidylyltransferase activity(GO:0004605)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0047023	androsterone dehydrogenase activity(GO:0047023)
0.0	0.1	GO:0003831	beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0043560	insulin receptor substrate binding(GO:0043560)
0.0	0.0	GO:0034648	histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	0.0	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0002046	opsin binding(GO:0002046)
0.0	0.1	GO:0042979	ornithine decarboxylase regulator activity(GO:0042979)
0.0	0.1	GO:0004396	glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0	0.0	GO:0019237	centromeric DNA binding(GO:0019237)
0.0	0.0	GO:0031433	telethonin binding(GO:0031433)
0.0	0.1	GO:0015197	peptide transporter activity(GO:0015197)
0.0	0.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.0	GO:0097108	hedgehog family protein binding(GO:0097108)
0.0	0.1	GO:0038191	neuropilin binding(GO:0038191)
0.0	0.1	GO:0005536	glucose binding(GO:0005536)
0.0	0.1	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0	0.1	GO:0052630	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.0	GO:0031826	type 2A serotonin receptor binding(GO:0031826)
0.0	0.0	GO:0032139	dinucleotide insertion or deletion binding(GO:0032139)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.0	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.0	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.1	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.0	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.0	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.2	GO:0005528	macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0015643	toxic substance binding(GO:0015643)
0.0	0.0	GO:0015038	glutathione disulfide oxidoreductase activity(GO:0015038)
0.0	0.0	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.3	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.3	GO:0030351	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol tetrakisphosphate phosphatase activity(GO:0052743) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.1	GO:0008061	chitin binding(GO:0008061)
0.0	0.0	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.0	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.0	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.6	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.6	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.2	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.6	NABA PROTEOGLYCANS	Genes encoding proteoglycans
0.0	0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.0	0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.6	PID HEDGEHOG GLI PATHWAY	Hedgehog signaling events mediated by Gli proteins
0.0	0.6	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.0	0.4	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	0.5	PID DELTA NP63 PATHWAY	Validated transcriptional targets of deltaNp63 isoforms
0.0	0.4	PID FOXM1 PATHWAY	FOXM1 transcription factor network
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	0.0	NABA BASEMENT MEMBRANES	Genes encoding structural components of basement membranes
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.1	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.0	0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.1	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.2	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	1.5	REACTOME SHC1 EVENTS IN EGFR SIGNALING	Genes involved in SHC1 events in EGFR signaling
0.1	0.6	REACTOME VITAMIN B5 PANTOTHENATE METABOLISM	Genes involved in Vitamin B5 (pantothenate) metabolism
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.1	REACTOME SHC RELATED EVENTS	Genes involved in SHC-related events
0.0	0.3	REACTOME SIGNALING BY FGFR3 MUTANTS	Genes involved in Signaling by FGFR3 mutants
0.0	0.3	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0	0.2	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.6	REACTOME REGULATION OF BETA CELL DEVELOPMENT	Genes involved in Regulation of beta-cell development
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY12	Genes involved in ADP signalling through P2Y purinoceptor 12
0.0	0.2	REACTOME ENDOGENOUS STEROLS	Genes involved in Endogenous sterols
0.0	0.3	REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1	Genes involved in Regulation of AMPK activity via LKB1
0.0	0.1	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.2	REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Extrinsic Pathway for Apoptosis
0.0	0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.6	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0	0.0	REACTOME SIGNALING BY FGFR	Genes involved in Signaling by FGFR
0.0	0.2	REACTOME METABOLISM OF PORPHYRINS	Genes involved in Metabolism of porphyrins
0.0	0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0	0.2	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP

Results for Tcf21_Msc

Z-value: 1.61

Motif logo

Transcription factors associated with Tcf21_Msc

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tcf21_Msc motif across conditions

Conditions sorted by the z-value of the Tcf21_Msc motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf21_Msc

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: