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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Tcf3

Z-value: 1.36

Motif logo

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Transcription factors associated with Tcf3

Gene Symbol Gene ID Gene Info
Tcf3
ENSMUSG00000020167.8 transcription factor 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr10_80423960_80424130Tcf321850.140379-0.986.2e-04Click!
chr10_80444503_80444654Tcf3109310.085381-0.749.3e-02Click!
chr10_80433536_80433845Tcf3430.943195-0.691.3e-01Click!
chr10_80446179_80446497Tcf3126910.083839-0.661.5e-01Click!
chr10_80435895_80436307Tcf324540.136501-0.641.7e-01Click!

Activity of the Tcf3 motif across conditions

Conditions sorted by the z-value of the Tcf3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_19851376_19851638 1.43 Gm12029
 predicted gene 12029
 67855
 0.1
chr3_89147086_89147561 0.73 Hcn3
 hyperpolarization-activated, cyclic nucleotide-gated K+ 3
 3891
 0.08
chr12_104087488_104087669 0.57 Serpina4-ps1
 serine (or cysteine) peptidase inhibitor, clade A, member 4, pseudogene 1
 6929
 0.1
chr10_111318102_111318256 0.56 Gm40761
 predicted gene, 40761
 18945
 0.17
chr10_91261198_91261441 0.52 Gm18705
 predicted gene, 18705
 1975
 0.31
chr15_3468356_3468528 0.51 Ghr
 growth hormone receptor
 3202
 0.36
chr9_74366017_74366190 0.47 Nr1h2-ps
 nuclear receptor subfamily 1, group H, member 2, pseudogene
 1040
 0.56
chr19_18146304_18146531 0.44 Gm18610
 predicted gene, 18610
 59378
 0.14
chr4_10854377_10854556 0.43 Gm12919
 predicted gene 12919
 623
 0.61
chr15_3513860_3514011 0.42 Ghr
 growth hormone receptor
 42291
 0.19
chr16_5140582_5140765 0.42 Sec14l5
 SEC14-like lipid binding 5
 6436
 0.13
chr9_122850000_122850173 0.42 Gm47140
 predicted gene, 47140
 1668
 0.22
chr19_20723027_20723214 0.41 Aldh1a7
 aldehyde dehydrogenase family 1, subfamily A7
 4442
 0.3
chr8_66494561_66494830 0.39 Gm32568
 predicted gene, 32568
 364
 0.85
chr11_16816577_16816728 0.38 Egfros
 epidermal growth factor receptor, opposite strand
 14050
 0.21
chr11_120819185_120819682 0.38 Fasn
 fatty acid synthase
 3978
 0.11
chr7_24919736_24919914 0.37 Arhgef1
 Rho guanine nucleotide exchange factor (GEF) 1
 623
 0.53
chr2_58769900_58770051 0.36 Upp2
 uridine phosphorylase 2
 4650
 0.24
chr17_10093572_10093736 0.36 Qk
 quaking
 119920
 0.06
chr13_58192282_58192443 0.35 Gm48357
 predicted gene, 48357
 1044
 0.37
chr2_152359606_152359999 0.35 Gm14165
 predicted gene 14165
 6187
 0.1
chr11_5904597_5904748 0.35 Gck
 glucokinase
 2585
 0.17
chr11_16868479_16868644 0.34 Egfr
 epidermal growth factor receptor
 9589
 0.2
chr11_16858660_16858826 0.33 Egfr
 epidermal growth factor receptor
 19407
 0.18
chr13_19246519_19246807 0.33 Trgc3
 T cell receptor gamma, constant 3
 14221
 0.22
chr8_93180612_93180763 0.32 Ces1d
 carboxylesterase 1D
 5398
 0.15
chr9_122848440_122848788 0.31 Gm47140
 predicted gene, 47140
 196
 0.89
chr4_117831574_117831756 0.31 Slc6a9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
 2841
 0.16
chr5_130303522_130303878 0.31 Tyw1
 tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
 44770
 0.1
chr11_106412764_106412932 0.31 Icam2
 intercellular adhesion molecule 2
 24773
 0.12
chr1_50806470_50806812 0.31 Gm28321
 predicted gene 28321
 8734
 0.28
chr11_22372894_22373087 0.31 Rpsa-ps3
 ribosomal protein SA, pseudogene 3
 13302
 0.21
chr6_37347891_37348042 0.30 Creb3l2
 cAMP responsive element binding protein 3-like 2
 11431
 0.26
chr8_120046709_120046884 0.30 Gm15684
 predicted gene 15684
 1509
 0.32
chr1_59202432_59202591 0.29 Als2
 alsin Rho guanine nucleotide exchange factor
 16615
 0.14
chr11_16833397_16833632 0.29 Egfros
 epidermal growth factor receptor, opposite strand
 2812
 0.3
chr10_111314954_111315105 0.29 Bbs10
 Bardet-Biedl syndrome 10 (human)
 16350
 0.18
chr2_49177399_49177550 0.28 Gm13510
 predicted gene 13510
 7544
 0.27
chr16_49907450_49907601 0.28 Cd47
 CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
 40692
 0.2
chr19_57506666_57506817 0.28 6720468P15Rik
 RIKEN cDNA 6720468P15 gene
 1823
 0.28
chr12_30372401_30372579 0.28 Sntg2
 syntrophin, gamma 2
 775
 0.73
chr3_87801773_87801942 0.28 Insrr
 insulin receptor-related receptor
 86
 0.95
chr15_58960813_58961185 0.28 Mtss1
 MTSS I-BAR domain containing 1
 4159
 0.17
chr2_101762531_101762726 0.28 Prr5l
 proline rich 5 like
 35022
 0.17
chr13_113844856_113845031 0.28 Arl15
 ADP-ribosylation factor-like 15
 50321
 0.11
chr1_9578333_9578671 0.27 Gm6161
 predicted gene 6161
 3954
 0.16
chr11_70083308_70083461 0.27 Asgr2
 asialoglycoprotein receptor 2
 9260
 0.09
chr1_164426310_164426497 0.27 Gm37411
 predicted gene, 37411
 1690
 0.31
chr15_85233381_85233563 0.27 Fbln1
 fibulin 1
 27467
 0.17
chr12_108292499_108292690 0.27 Hhipl1
 hedgehog interacting protein-like 1
 13676
 0.15
chr5_113141351_113141509 0.26 4930557B06Rik
 RIKEN cDNA 4930557B06 gene
 1019
 0.36
chr4_102511795_102511975 0.26 Pde4b
 phosphodiesterase 4B, cAMP specific
 41488
 0.21
chr6_55108463_55108627 0.26 Crhr2
 corticotropin releasing hormone receptor 2
 7972
 0.19
chr2_167292312_167292496 0.26 Gm11473
 predicted gene 11473
 10627
 0.16
chr15_75047474_75047625 0.26 Ly6c1
 lymphocyte antigen 6 complex, locus C1
 1120
 0.32
chr11_51494380_51494743 0.25 Col23a1
 collagen, type XXIII, alpha 1
 79871
 0.07
chr5_24502879_24503079 0.25 Agap3
 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
 22807
 0.08
chr16_11098511_11098684 0.25 Txndc11
 thioredoxin domain containing 11
 11245
 0.1
chr10_86872197_86872354 0.25 Stab2
 stabilin 2
 6683
 0.14
chr2_17326719_17326870 0.25 Nebl
 nebulette
 34292
 0.22
chr15_58993520_58993677 0.25 4930544F09Rik
 RIKEN cDNA 4930544F09 gene
 9462
 0.17
chr11_22893094_22893344 0.25 Gm24917
 predicted gene, 24917
 24318
 0.11
chr18_8328204_8328355 0.25 Gm5500
 predicted pseudogene 5500
 86850
 0.09
chr4_49553429_49553778 0.24 Aldob
 aldolase B, fructose-bisphosphate
 4057
 0.17
chr8_46385009_46385281 0.24 Gm45253
 predicted gene 45253
 743
 0.6
chr10_69208384_69208535 0.24 Rhobtb1
 Rho-related BTB domain containing 1
 93
 0.97
chr11_110499189_110499340 0.24 Map2k6
 mitogen-activated protein kinase kinase 6
 20225
 0.24
chr11_98770698_98771034 0.23 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 440
 0.69
chr7_15939282_15939433 0.23 Snord23
 small nucleolar RNA, C/D box 23
 487
 0.65
chr8_36548724_36548879 0.23 Dlc1
 deleted in liver cancer 1
 28468
 0.19
chr18_80261215_80262161 0.23 Slc66a2
 solute carrier family 66 member 2
 1152
 0.35
chr19_46632420_46632695 0.23 Wbp1l
 WW domain binding protein 1 like
 9156
 0.13
chr5_130042317_130042468 0.23 Crcp
 calcitonin gene-related peptide-receptor component protein
 188
 0.92
chr9_108401502_108401859 0.23 1700102P08Rik
 RIKEN cDNA 1700102P08 gene
 8846
 0.07
chr12_85299100_85299299 0.23 Zc2hc1c
 zinc finger, C2HC-type containing 1C
 10608
 0.1
chr15_98738867_98739043 0.22 Fkbp11
 FK506 binding protein 11
 10757
 0.09
chr2_121193827_121193979 0.22 Tubgcp4
 tubulin, gamma complex associated protein 4
 1956
 0.22
chr17_78241487_78241665 0.21 Crim1
 cysteine rich transmembrane BMP regulator 1 (chordin like)
 3804
 0.22
chr8_77012726_77012888 0.21 Nr3c2
 nuclear receptor subfamily 3, group C, member 2
 104535
 0.06
chr5_88367022_88367405 0.21 Amtn
 amelotin
 8895
 0.17
chr4_118002076_118002227 0.21 9530034E10Rik
 RIKEN cDNA 9530034E10 gene
 27115
 0.13
chr5_81910056_81910231 0.21 2900064F13Rik
 RIKEN cDNA 2900064F13 gene
 83327
 0.09
chr18_64006042_64006212 0.21 Gm6974
 predicted gene 6974
 75293
 0.09
chr2_20939712_20939881 0.21 Arhgap21
 Rho GTPase activating protein 21
 3623
 0.24
chr18_67579213_67579374 0.21 Gm17669
 predicted gene, 17669
 16899
 0.16
chr7_4647276_4647517 0.21 Ppp6r1
 protein phosphatase 6, regulatory subunit 1
 9
 0.94
chr17_24674148_24674299 0.20 Zfp598
 zinc finger protein 598
 2919
 0.09
chr11_16818044_16818409 0.20 Egfros
 epidermal growth factor receptor, opposite strand
 12476
 0.22
chr18_84376572_84376752 0.20 Gm37216
 predicted gene, 37216
 516
 0.84
chr11_120248567_120248734 0.20 Bahcc1
 BAH domain and coiled-coil containing 1
 11951
 0.09
chr2_52372456_52372665 0.20 Neb
 nebulin
 5030
 0.17
chr11_16798191_16798439 0.20 Egfros
 epidermal growth factor receptor, opposite strand
 32387
 0.16
chr10_81378463_81379124 0.20 Fzr1
 fizzy and cell division cycle 20 related 1
 277
 0.71
chr14_67917259_67917426 0.20 Dock5
 dedicator of cytokinesis 5
 16090
 0.22
chr13_4270977_4271134 0.20 Akr1c12
 aldo-keto reductase family 1, member C12
 8378
 0.15
chr13_69631727_69631878 0.20 Nsun2
 NOL1/NOP2/Sun domain family member 2
 1062
 0.36
chr12_105005460_105005678 0.20 Syne3
 spectrin repeat containing, nuclear envelope family member 3
 4240
 0.13
chr6_43272880_43273031 0.20 Arhgef5
 Rho guanine nucleotide exchange factor (GEF) 5
 1556
 0.25
chr9_107649361_107649537 0.19 Slc38a3
 solute carrier family 38, member 3
 6571
 0.08
chr4_53086731_53086906 0.19 Abca1
 ATP-binding cassette, sub-family A (ABC1), member 1
 45892
 0.13
chr10_4120834_4121002 0.19 Gm25515
 predicted gene, 25515
 16605
 0.2
chr14_78548923_78549074 0.19 Akap11
 A kinase (PRKA) anchor protein 11
 12190
 0.2
chr7_75611829_75612100 0.19 Akap13
 A kinase (PRKA) anchor protein 13
 124
 0.97
chr15_59020453_59020630 0.19 Mtss1
 MTSS I-BAR domain containing 1
 20055
 0.17
chr13_96660106_96660425 0.19 Hmgcr
 3-hydroxy-3-methylglutaryl-Coenzyme A reductase
 3598
 0.18
chr4_49538717_49538957 0.19 Aldob
 aldolase B, fructose-bisphosphate
 29
 0.97
chr2_172938722_172938940 0.19 Bmp7
 bone morphogenetic protein 7
 1261
 0.45
chr3_75868999_75869188 0.19 Golim4
 golgi integral membrane protein 4
 9915
 0.24
chr18_76254679_76254860 0.19 Smad2
 SMAD family member 2
 6352
 0.2
chr6_38823949_38824290 0.19 Hipk2
 homeodomain interacting protein kinase 2
 5773
 0.25
chr19_37433970_37434137 0.19 Gm38345
 predicted gene, 38345
 603
 0.45
chr17_80697982_80698359 0.19 Map4k3
 mitogen-activated protein kinase kinase kinase kinase 3
 29854
 0.18
chr5_23462026_23462363 0.19 Kmt2e
 lysine (K)-specific methyltransferase 2E
 16361
 0.15
chr15_9079456_9079615 0.18 Nadk2
 NAD kinase 2, mitochondrial
 4258
 0.25
chr16_10366678_10366849 0.18 Gm1600
 predicted gene 1600
 19172
 0.14
chr14_24960151_24960328 0.18 Gm10398
 predicted gene 10398
 50825
 0.13
chr11_16769921_16770266 0.18 Egfr
 epidermal growth factor receptor
 17863
 0.19
chr7_31101720_31101871 0.18 Hpn
 hepsin
 719
 0.46
chr2_32409058_32409478 0.18 Gm13413
 predicted gene 13413
 3213
 0.12
chr12_103670437_103670601 0.18 Serpina16
 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 16
 4945
 0.12
chr1_126484684_126484835 0.18 Nckap5
 NCK-associated protein 5
 7983
 0.32
chr2_127367630_127367825 0.18 Adra2b
 adrenergic receptor, alpha 2b
 4441
 0.16
chr4_130708524_130708794 0.18 Snord85
 small nucleolar RNA, C/D box 85
 40975
 0.1
chr9_57214145_57214320 0.18 Trcg1
 taste receptor cell gene 1
 22324
 0.12
chr16_30664084_30664254 0.18 Fam43a
 family with sequence similarity 43, member A
 64446
 0.1
chr1_62809972_62810173 0.18 Gm37121
 predicted gene, 37121
 770
 0.67
chr12_32707351_32707528 0.18 Gm18726
 predicted gene, 18726
 2722
 0.31
chr2_134826467_134826626 0.17 Gm14036
 predicted gene 14036
 22597
 0.2
chr3_24630236_24630408 0.17 Gm24704
 predicted gene, 24704
 68248
 0.14
chr6_84235021_84235302 0.17 Gm44127
 predicted gene, 44127
 9909
 0.22
chr15_99101408_99101603 0.17 Dnajc22
 DnaJ heat shock protein family (Hsp40) member C22
 2093
 0.16
chr8_111739071_111739223 0.17 Bcar1
 breast cancer anti-estrogen resistance 1
 4662
 0.21
chr4_86373682_86373833 0.17 Gm12550
 predicted gene 12550
 68584
 0.11
chr15_10206547_10206755 0.17 Prlr
 prolactin receptor
 6814
 0.3
chr2_174330237_174330577 0.17 Gnas
 GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
 120
 0.95
chr2_124609977_124610547 0.17 Sema6d
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
 34
 0.99
chr8_26078485_26078636 0.17 Hook3
 hook microtubule tethering protein 3
 817
 0.46
chr15_76227819_76227970 0.17 Plec
 plectin
 1603
 0.17
chr13_108042230_108042425 0.17 Smim15
 small integral membrane protein 15
 2119
 0.37
chr9_67137735_67137898 0.17 Gm19299
 predicted gene, 19299
 4255
 0.21
chr11_59226278_59226466 0.17 Arf1
 ADP-ribosylation factor 1
 1790
 0.2
chr16_26669940_26670091 0.17 Il1rap
 interleukin 1 receptor accessory protein
 45859
 0.18
chr7_68728361_68728534 0.16 Gm44692
 predicted gene 44692
 1980
 0.37
chr5_135703012_135703168 0.16 Gm16061
 predicted gene 16061
 4071
 0.13
chr5_36176782_36177189 0.16 Psapl1
 prosaposin-like 1
 27036
 0.21
chr4_139454119_139454298 0.16 Ubr4
 ubiquitin protein ligase E3 component n-recognin 4
 9051
 0.18
chr6_38870157_38870322 0.16 Tbxas1
 thromboxane A synthase 1, platelet
 5165
 0.22
chr19_9027860_9028087 0.16 Ahnak
 AHNAK nucleoprotein (desmoyokin)
 28313
 0.09
chr17_35865754_35865905 0.16 Ppp1r18
 protein phosphatase 1, regulatory subunit 18
 204
 0.76
chr8_11145382_11145560 0.16 Gm44717
 predicted gene 44717
 3775
 0.2
chr14_25508473_25508633 0.16 Zmiz1
 zinc finger, MIZ-type containing 1
 5898
 0.16
chr1_130387327_130387514 0.16 Cd55b
 CD55 molecule, decay accelerating factor for complement B
 35320
 0.11
chr15_59014305_59014721 0.16 Mtss1
 MTSS I-BAR domain containing 1
 26083
 0.16
chr3_107230665_107230816 0.16 A630076J17Rik
 RIKEN cDNA A630076J17 gene
 126
 0.94
chr5_51144711_51144875 0.16 Gm44377
 predicted gene, 44377
 78881
 0.1
chr7_79308613_79308815 0.16 Gm39041
 predicted gene, 39041
 9689
 0.14
chr6_51573063_51573238 0.16 Snx10
 sorting nexin 10
 28584
 0.17
chr15_89102253_89102404 0.16 Tubgcp6
 tubulin, gamma complex associated protein 6
 44
 0.94
chr15_55843743_55843894 0.16 Sntb1
 syntrophin, basic 1
 62492
 0.11
chr6_136906748_136907166 0.16 Erp27
 endoplasmic reticulum protein 27
 15183
 0.11
chr14_67884776_67884962 0.16 Mir6539
 microRNA 6539
 25124
 0.2
chr3_129557154_129557334 0.16 Elovl6
 ELOVL family member 6, elongation of long chain fatty acids (yeast)
 4864
 0.19
chr14_16478758_16478933 0.16 Top2b
 topoisomerase (DNA) II beta
 53417
 0.13
chr15_83772573_83772737 0.15 Mpped1
 metallophosphoesterase domain containing 1
 6812
 0.24
chr17_47593664_47594464 0.15 Ccnd3
 cyclin D3
 249
 0.86
chr12_110221880_110222031 0.15 Gm40576
 predicted gene, 40576
 14407
 0.11
chr11_117233984_117234135 0.15 Septin9
 septin 9
 1774
 0.34
chr11_50104096_50104296 0.15 Rnf130
 ring finger protein 130
 10522
 0.12
chr11_6016490_6016658 0.15 Camk2b
 calcium/calmodulin-dependent protein kinase II, beta
 16126
 0.16
chr5_138948306_138948628 0.15 Pdgfa
 platelet derived growth factor, alpha
 45814
 0.12
chr19_48703871_48704022 0.15 Sorcs3
 sortilin-related VPS10 domain containing receptor 3
 270
 0.95
chr16_92637112_92637263 0.15 Gm26626
 predicted gene, 26626
 24373
 0.19
chr13_9199577_9199754 0.15 Gm8784
 predicted gene 8784
 23872
 0.13
chr8_71495277_71495471 0.15 Gtpbp3
 GTP binding protein 3
 5915
 0.08
chr5_134209731_134209889 0.15 Gtf2ird2
 GTF2I repeat domain containing 2
 3153
 0.17
chr14_60976604_60976847 0.15 Tnfrsf19
 tumor necrosis factor receptor superfamily, member 19
 840
 0.7
chr10_68103006_68103157 0.15 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 33545
 0.18
chr3_138280557_138280953 0.15 Adh1
 alcohol dehydrogenase 1 (class I)
 3104
 0.16
chr10_11306105_11306256 0.15 Gm48666
 predicted gene, 48666
 24235
 0.12
chr16_95851988_95852139 0.15 1600002D24Rik
 RIKEN cDNA 1600002D24 gene
 6293
 0.2
chr10_117884880_117885031 0.15 Gm32552
 predicted gene, 32552
 18240
 0.14
chr7_137286258_137286429 0.15 Ebf3
 early B cell factor 3
 18805
 0.18
chr1_73513962_73514123 0.15 Gm9553
 predicted gene 9553
 1996
 0.31
chr1_67197545_67197701 0.15 Gm15668
 predicted gene 15668
 51577
 0.13
chr6_67036040_67036201 0.15 E230016M11Rik
 RIKEN cDNA E230016M11 gene
 479
 0.61
chr7_99165012_99165417 0.15 Dgat2
 diacylglycerol O-acyltransferase 2
 4892
 0.14
chr2_18159543_18159694 0.14 Gm25147
 predicted gene, 25147
 931
 0.48
chr11_22494745_22494936 0.14 Gm12051
 predicted gene 12051
 11232
 0.19
chr19_53786299_53786461 0.14 Rbm20
 RNA binding motif protein 20
 6928
 0.18
chr6_139624876_139625027 0.14 Pik3c2g
 phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma
 3063
 0.3
chr15_64362676_64362949 0.14 Asap1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain1
 12926
 0.19
chr19_29862924_29863094 0.14 Gm50380
 predicted gene, 50380
 12208
 0.18
chr6_101046905_101047082 0.14 Gm43948
 predicted gene, 43948
 12178
 0.18
chr7_119523427_119523676 0.14 Pdilt
 protein disulfide isomerase-like, testis expressed
 62
 0.95
chr3_41498956_41499107 0.14 Platr4
 pluripotency associated transcript 4
 5839
 0.14
chr10_69257688_69257866 0.14 Rhobtb1
 Rho-related BTB domain containing 1
 7860
 0.2
chr12_103805644_103805795 0.14 Gm17043
 predicted gene 17043
 1357
 0.28
chr2_27767443_27767901 0.14 Rxra
 retinoid X receptor alpha
 27471
 0.21
chr1_181529523_181529674 0.14 Ccdc121
 coiled-coil domain containing 121
 18147
 0.19
chr1_157101218_157101391 0.14 Tex35
 testis expressed 35
 7084
 0.18

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.3 GO:0010446 response to alkaline pH(GO:0010446)
0.1 0.2 GO:1900169 regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.1 0.2 GO:0061624 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.1 0.2 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.1 0.2 GO:2000828 regulation of parathyroid hormone secretion(GO:2000828)
0.0 0.2 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:0006549 isoleucine metabolic process(GO:0006549)
0.0 0.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.1 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.1 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0010693 negative regulation of alkaline phosphatase activity(GO:0010693)
0.0 0.1 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.2 GO:0010871 negative regulation of receptor biosynthetic process(GO:0010871)
0.0 0.1 GO:0009732 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.0 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.1 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.0 0.1 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.0 0.1 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0032289 central nervous system myelin formation(GO:0032289)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.1 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.1 GO:0044805 lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1901078 negative regulation of relaxation of muscle(GO:1901078)
0.0 0.1 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:1900452 regulation of long term synaptic depression(GO:1900452)
0.0 0.1 GO:0030421 defecation(GO:0030421)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0006526 arginine biosynthetic process(GO:0006526)
0.0 0.1 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.0 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0 0.1 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.1 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.1 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0 0.0 GO:0038044 transforming growth factor-beta secretion(GO:0038044) regulation of transforming growth factor-beta secretion(GO:2001201)
0.0 0.0 GO:0061010 gall bladder development(GO:0061010)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.1 GO:0051295 establishment of meiotic spindle localization(GO:0051295)
0.0 0.0 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.0 0.0 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.0 GO:0070175 positive regulation of enamel mineralization(GO:0070175)
0.0 0.0 GO:0006982 response to lipid hydroperoxide(GO:0006982)
0.0 0.1 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.0 GO:0010909 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0 0.0 GO:0030578 PML body organization(GO:0030578)
0.0 0.1 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 0.0 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.0 GO:0006068 ethanol catabolic process(GO:0006068)
0.0 0.0 GO:0034140 negative regulation of toll-like receptor 3 signaling pathway(GO:0034140)
0.0 0.1 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.0 0.0 GO:0048320 axial mesoderm formation(GO:0048320)
0.0 0.0 GO:0072095 regulation of branch elongation involved in ureteric bud branching(GO:0072095)
0.0 0.0 GO:0035793 cell migration involved in metanephros development(GO:0035788) metanephric mesenchymal cell migration(GO:0035789) positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) regulation of metanephric mesenchymal cell migration(GO:2000589) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.0 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.1 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0 0.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.0 GO:0072053 renal inner medulla development(GO:0072053)
0.0 0.0 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.0 GO:0008228 opsonization(GO:0008228)
0.0 0.1 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.0 0.1 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.0 GO:0090427 activation of meiosis(GO:0090427)
0.0 0.0 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.0 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 0.2 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 0.0 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.0 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.0 GO:0006083 acetate metabolic process(GO:0006083)
0.0 0.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 0.2 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 0.1 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.2 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 0.1 GO:0031094 platelet dense tubular network(GO:0031094)
0.0 0.1 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.0 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.0 GO:0071953 elastic fiber(GO:0071953)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.1 GO:0051718 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.1 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.0 GO:0004030 aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030)
0.0 0.1 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0 0.1 GO:0016901 oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptor(GO:0016901)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.0 GO:0004771 sterol esterase activity(GO:0004771)
0.0 0.0 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.0 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.0 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.1 GO:0004396 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971) thiol oxidase activity(GO:0016972)
0.0 0.0 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.0 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.1 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.0 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.0 GO:2001070 starch binding(GO:2001070)
0.0 0.0 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.0 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.5 PID RHOA REG PATHWAY Regulation of RhoA activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 0.1 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.1 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.2 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor
0.0 0.0 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta