Project

ENCSR904DTN: DNase-seq of mouse liver in constant darkness

Navigation

Downloads

CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tead1

Z-value: 1.87

Motif logo

Transcription factors associated with Tead1

Gene Symbol	Gene ID	Gene Info
Tead1 Ensembl NCBI MGI UniProt	ENSMUSG00000055320.10	Tead1

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Tead1	chr7_112697188_112697354	5573	0.180704	0.88	1.9e-02	Click!
Tead1	chr7_112697541_112697813	5979	0.178198	0.87	2.3e-02	Click!
Tead1	chr7_112688480_112688662	3127	0.214614	0.86	2.6e-02	Click!
Tead1	chr7_112807573_112807746	31975	0.191092	0.78	6.9e-02	Click!
Tead1	chr7_112788724_112788885	29258	0.192438	0.77	7.5e-02	Click!

Activity of the Tead1 motif across conditions

Conditions sorted by the z-value of the Tead1 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr10_24595287_24595581	1.44	Ccn2	cellular communication network factor 2	8	0.86
chr7_84457901_84458052	1.07	Gm45175	predicted gene 45175	13425	0.16
chr5_139317463_139317630	1.00	Adap1	ArfGAP with dual PH domains 1	8076	0.13
chr11_88173046_88173197	0.98	Cuedc1	CUE domain containing 1	9182	0.18
chr5_151412960_151413135	0.98	1700028E10Rik	RIKEN cDNA 1700028E10 gene	6521	0.17
chr12_8333733_8333892	0.96	Gm48071	predicted gene, 48071	2905	0.21
chr10_127544019_127544184	0.95	Lrp1	low density lipoprotein receptor-related protein 1	893	0.41
chr5_144258484_144258651	0.94	2900089D17Rik	RIKEN cDNA 2900089D17 gene	2381	0.19
chr3_88102838_88102989	0.89	Iqgap3	IQ motif containing GTPase activating protein 3	2229	0.18
chr17_35549631_35549795	0.89	Cdsn	corneodesmosin	2415	0.12
chr7_45710445_45711101	0.86	Sphk2	sphingosine kinase 2	2670	0.09
chr15_99041222_99041434	0.83	Tuba1c	tubulin, alpha 1C	11007	0.09
chr15_62501057_62501225	0.81	Gm41333	predicted gene, 41333	66834	0.14
chr2_25176703_25176854	0.81	Nrarp	Notch-regulated ankyrin repeat protein	3980	0.08
chr7_110297212_110297456	0.80	Gm9132	predicted gene 9132	4667	0.2
chr7_45705992_45706174	0.79	Dbp	D site albumin promoter binding protein	799	0.31
chr4_117997646_117997813	0.78	9530034E10Rik	RIKEN cDNA 9530034E10 gene	22693	0.14
chr3_152143501_152143652	0.77	Gipc2	GIPC PDZ domain containing family, member 2	3212	0.17
chr13_69524173_69524569	0.77	Tent4a	terminal nucleotidyltransferase 4A	8061	0.13
chr14_7874610_7874781	0.77	Flnb	filamin, beta	10046	0.2
chr4_128946455_128946665	0.74	Gm15904	predicted gene 15904	10555	0.15
chr15_98868738_98868889	0.74	Kmt2d	lysine (K)-specific methyltransferase 2D	2370	0.12
chr15_93916844_93917358	0.73	9430014N10Rik	RIKEN cDNA 9430014N10 gene	10010	0.25
chr17_5075206_5075364	0.71	Arid1b	AT rich interactive domain 1B (SWI-like)	34707	0.18
chr13_112405475_112405627	0.69	2810403G07Rik	RIKEN cDNA 2810403G07 gene	11814	0.14
chr10_20749070_20749231	0.67	Gm48651	predicted gene, 48651	6967	0.23
chr2_29731675_29731853	0.67	Rapgef1	Rap guanine nucleotide exchange factor (GEF) 1	797	0.51
chr1_182670647_182670811	0.66	Gm37516	predicted gene, 37516	9210	0.19
chr15_97773204_97773381	0.66	Slc48a1	solute carrier family 48 (heme transporter), member 1	5228	0.13
chr14_27350759_27350910	0.66	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	10555	0.2
chr1_40217644_40217810	0.66	Il1r1	interleukin 1 receptor, type I	7353	0.21
chr18_64381354_64381662	0.65	Onecut2	one cut domain, family member 2	41488	0.11
chr5_148998636_148998818	0.64	Gm15406	predicted gene 15406	2161	0.14
chr17_47193022_47193193	0.64	Trerf1	transcriptional regulating factor 1	19280	0.21
chr11_108198624_108198935	0.63	Gm11655	predicted gene 11655	16929	0.25
chr4_135820255_135820445	0.63	Myom3	myomesin family, member 3	19706	0.11
chr5_139395256_139395425	0.63	Gpr146	G protein-coupled receptor 146	5555	0.12
chr18_61360632_61360830	0.61	Gm25301	predicted gene, 25301	37082	0.11
chr14_65863199_65863389	0.60	Ccdc25	coiled-coil domain containing 25	25934	0.15
chr11_60249007_60249158	0.60	Tom1l2	target of myb1-like 2 (chicken)	3413	0.16
chr1_13103635_13103786	0.58	Prdm14	PR domain containing 14	23453	0.13
chr9_15525292_15525443	0.58	Smco4	single-pass membrane protein with coiled-coil domains 4	4508	0.2
chr7_34319277_34319447	0.57	4931406P16Rik	RIKEN cDNA 4931406P16 gene	5811	0.13
chr19_10054766_10055233	0.57	Fads3	fatty acid desaturase 3	1253	0.35
chr4_105179379_105179579	0.56	Plpp3	phospholipid phosphatase 3	22132	0.24
chr2_25145394_25145761	0.55	Gm13387	predicted gene 13387	181	0.87
chrX_169054094_169054245	0.55	Arhgap6	Rho GTPase activating protein 6	17558	0.24
chr3_121982496_121982688	0.55	Arhgap29	Rho GTPase activating protein 29	1042	0.54
chr17_78206502_78206668	0.55	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)	5520	0.16
chr2_178993954_178994105	0.55	Gm14314	predicted gene 14314	27104	0.26
chr17_84074449_84074742	0.54	4933433H22Rik	RIKEN cDNA 4933433H22 gene	4065	0.18
chr6_28681979_28682177	0.54	Snd1	staphylococcal nuclease and tudor domain containing 1	22831	0.21
chr1_57890324_57890494	0.54	Spats2l	spermatogenesis associated, serine-rich 2-like	11662	0.2
chr3_84298294_84298452	0.53	Trim2	tripartite motif-containing 2	6368	0.27
chr14_54572931_54573082	0.53	Ajuba	ajuba LIM protein	924	0.35
chr1_184072575_184072786	0.53	Dusp10	dual specificity phosphatase 10	38299	0.17
chr18_35830960_35831336	0.53	Gm29417	predicted gene 29417	55	0.92
chr12_37050724_37050882	0.53	Gm48617	predicted gene, 48617	1586	0.37
chr11_16588986_16589143	0.52	Gm12663	predicted gene 12663	47002	0.12
chr11_87735822_87735981	0.52	Supt4a	SPT4A, DSIF elongation factor subunit	1651	0.19
chr7_89558667_89558818	0.51	Gm45064	predicted gene 45064	6376	0.17
chr13_44409176_44409378	0.51	Gm33958	predicted gene, 33958	18160	0.15
chr10_22875325_22875476	0.51	Tcf21	transcription factor 21	55226	0.11
chr1_184069803_184070002	0.51	Dusp10	dual specificity phosphatase 10	35521	0.18
chr7_132723077_132723229	0.51	Fam53b	family with sequence similarity 53, member B	53763	0.11
chr7_34485188_34485527	0.50	Gm12780	predicted gene 12780	10708	0.16
chr15_83440834_83440989	0.50	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	8087	0.16
chr12_111691358_111691542	0.50	Gm36635	predicted gene, 36635	11632	0.09
chr10_20669582_20669754	0.49	Gm17230	predicted gene 17230	44033	0.15
chr8_128447394_128447576	0.49	Nrp1	neuropilin 1	88088	0.08
chr6_35875002_35875227	0.49	Gm43442	predicted gene 43442	51597	0.17
chr17_31965712_31965881	0.49	Gm17572	predicted gene, 17572	15262	0.15
chr10_17786858_17787009	0.48	Gm20655	predicted gene 20655	8395	0.18
chr15_75270297_75270448	0.48	Ly6f	lymphocyte antigen 6 complex, locus F	1670	0.23
chr13_115090695_115090877	0.48	Pelo	pelota mRNA surveillance and ribosome rescue factor	600	0.58
chr2_80038295_80038479	0.48	Pde1a	phosphodiesterase 1A, calmodulin-dependent	642	0.82
chr9_108600199_108600350	0.47	P4htm	prolyl 4-hydroxylase, transmembrane (endoplasmic reticulum)	2607	0.09
chr5_121686462_121686752	0.47	Brap	BRCA1 associated protein	3679	0.14
chr15_75593070_75593251	0.46	Gpihbp1	GPI-anchored HDL-binding protein 1	3468	0.15
chr11_75134022_75134199	0.46	Smg6	Smg-6 homolog, nonsense mediated mRNA decay factor (C. elegans)	1675	0.24
chr15_96674208_96674363	0.46	Gm22045	predicted gene, 22045	2492	0.26
chr12_86948719_86948887	0.46	Cipc	CLOCK interacting protein, circadian	1313	0.41
chr19_29143356_29143666	0.46	Mir101b	microRNA 101b	8232	0.15
chr6_137142914_137143065	0.45	Rerg	RAS-like, estrogen-regulated, growth-inhibitor	2926	0.27
chr17_79451613_79451775	0.45	Cdc42ep3	CDC42 effector protein (Rho GTPase binding) 3	96603	0.07
chr7_65469723_65469896	0.45	Gm44792	predicted gene 44792	11412	0.21
chr11_82033062_82033234	0.45	Ccl2	chemokine (C-C motif) ligand 2	2423	0.18
chr2_58765113_58765779	0.45	Upp2	uridine phosphorylase 2	121	0.97
chr16_16224499_16224674	0.44	Pkp2	plakophilin 2	11268	0.19
chrX_129413614_129413812	0.43	Gm14986	predicted gene 14986	104813	0.07
chr12_58323949_58324220	0.43	Clec14a	C-type lectin domain family 14, member a	54794	0.16
chr8_70665733_70665894	0.43	Pgpep1	pyroglutamyl-peptidase I	5425	0.09
chr9_31223628_31223791	0.43	Aplp2	amyloid beta (A4) precursor-like protein 2	11894	0.18
chr6_28704741_28704911	0.42	Snd1	staphylococcal nuclease and tudor domain containing 1	83	0.98
chr11_102221971_102222363	0.42	Hdac5	histone deacetylase 5	3238	0.12
chr5_53193460_53193736	0.42	Sel1l3	sel-1 suppressor of lin-12-like 3 (C. elegans)	19717	0.18
chr2_60698236_60698402	0.42	Itgb6	integrin beta 6	7259	0.25
chr3_82054654_82054805	0.42	Gucy1b1	guanylate cyclase 1, soluble, beta 1	19407	0.17
chr19_40241408_40241559	0.41	Pdlim1	PDZ and LIM domain 1 (elfin)	10678	0.15
chr8_126584050_126584216	0.41	Irf2bp2	interferon regulatory factor 2 binding protein 2	9853	0.22
chr7_57560848_57561014	0.41	Mir6389	microRNA 6389	20130	0.19
chr1_184852414_184852593	0.41	Mtarc2	mitochondrial amidoxime reducing component 2	6052	0.17
chr15_64362676_64362949	0.41	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	12926	0.19
chr9_90260660_90260839	0.41	Tbc1d2b	TBC1 domain family, member 2B	4822	0.19
chr7_31108093_31108358	0.41	Hpn	hepsin	2772	0.13
chr11_8484705_8484960	0.41	Tns3	tensin 3	16157	0.28
chr3_10211563_10211714	0.40	Fabp4	fatty acid binding protein 4, adipocyte	3062	0.13
chr7_132736194_132736348	0.40	Fam53b	family with sequence similarity 53, member B	40645	0.13
chr7_99168662_99168821	0.40	Dgat2	diacylglycerol O-acyltransferase 2	1365	0.33
chr9_46049413_46049714	0.40	Sik3	SIK family kinase 3	36563	0.11
chr1_191075136_191075311	0.40	Gm38188	predicted gene, 38188	3457	0.13
chr2_127603534_127603695	0.40	Mrps5	mitochondrial ribosomal protein S5	3581	0.16
chr10_77448892_77449069	0.40	Gm35920	predicted gene, 35920	8937	0.17
chr16_52267318_52267489	0.40	Alcam	activated leukocyte cell adhesion molecule	1658	0.53
chr17_75465392_75465653	0.40	Rasgrp3	RAS, guanyl releasing protein 3	36	0.99
chr10_117729488_117729656	0.40	Slc35e3	solute carrier family 35, member E3	15370	0.13
chr9_35039370_35039714	0.39	St3gal4	ST3 beta-galactoside alpha-2,3-sialyltransferase 4	16252	0.16
chr4_149923922_149924117	0.39	Spsb1	splA/ryanodine receptor domain and SOCS box containing 1	1548	0.34
chr3_151880053_151880221	0.39	Gm43617	predicted gene 43617	7166	0.17
chr12_112587593_112587810	0.39	Inf2	inverted formin, FH2 and WH2 domain containing	1083	0.43
chr5_138979896_138980396	0.39	Pdgfa	platelet derived growth factor, alpha	14135	0.17
chr17_57224886_57225407	0.39	C3	complement component 3	2319	0.17
chr6_113668529_113668873	0.39	Irak2	interleukin-1 receptor-associated kinase 2	149	0.89
chr17_4479666_4479822	0.39	4930517M08Rik	RIKEN cDNA 4930517M08 gene	155234	0.04
chr6_89345028_89345199	0.39	Gm44207	predicted gene, 44207	27	0.97
chr5_142440070_142440526	0.39	Ap5z1	adaptor-related protein complex 5, zeta 1 subunit	23646	0.17
chr10_37250196_37250360	0.39	4930543K20Rik	RIKEN cDNA 4930543K20 gene	13470	0.25
chr4_95389795_95389977	0.39	Gm29064	predicted gene 29064	12904	0.24
chr11_121520060_121520211	0.39	Zfp750	zinc finger protein 750	802	0.62
chr5_24969338_24969503	0.38	1500035N22Rik	RIKEN cDNA 1500035N22 gene	16422	0.17
chr4_106590222_106590393	0.38	Gm12744	predicted gene 12744	1199	0.34
chr5_22431872_22432035	0.38	n-R5s170	nuclear encoded rRNA 5S 170	1510	0.34
chr9_116873050_116873366	0.38	Rbms3	RNA binding motif, single stranded interacting protein	50389	0.18
chr2_124753827_124753978	0.38	Gm13994	predicted gene 13994	45247	0.19
chr7_35146051_35146625	0.38	Gm35665	predicted gene, 35665	4889	0.12
chr9_63959217_63959382	0.38	Gm36033	predicted gene, 36033	22178	0.16
chr15_84193628_84193804	0.38	Samm50	SAMM50 sorting and assembly machinery component	1475	0.26
chr8_91377438_91377598	0.38	Fto	fat mass and obesity associated	13037	0.15
chr11_102430263_102430421	0.38	Grn	granulin	20	0.95
chr8_122461364_122461539	0.37	Snai3	snail family zinc finger 3	718	0.43
chr3_129551702_129551883	0.37	Elovl6	ELOVL family member 6, elongation of long chain fatty acids (yeast)	588	0.72
chr15_64345201_64345377	0.37	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	4597	0.21
chr1_61971987_61972299	0.37	Gm29640	predicted gene 29640	9064	0.27
chr3_82952346_82952497	0.37	Gm30097	predicted gene, 30097	43164	0.1
chr9_4380683_4380845	0.36	Msantd4	Myb/SANT-like DNA-binding domain containing 4 with coiled-coils	2771	0.26
chr4_150707281_150707454	0.36	Gm16079	predicted gene 16079	28575	0.17
chr16_50753691_50753842	0.36	Dubr	Dppa2 upstream binding RNA	20993	0.17
chr10_28395793_28396016	0.36	Ptprk	protein tyrosine phosphatase, receptor type, K	164247	0.04
chr11_6021859_6022054	0.35	Camk2b	calcium/calmodulin-dependent protein kinase II, beta	21508	0.15
chr5_89422485_89422688	0.35	Gc	vitamin D binding protein	13042	0.26
chr4_139580884_139581199	0.35	Iffo2	intermediate filament family orphan 2	6321	0.15
chr4_70521535_70521760	0.35	Megf9	multiple EGF-like-domains 9	13281	0.3
chr10_86161840_86162013	0.35	Gm15990	predicted gene 15990	36099	0.14
chr14_116448226_116448591	0.35	Gm38045	predicted gene, 38045	301807	0.01
chr16_34937792_34937966	0.35	1700119H24Rik	RIKEN cDNA 1700119H24 gene	1450	0.39
chr8_35920405_35920556	0.35	5430403N17Rik	RIKEN cDNA 5430403N17 gene	37523	0.14
chr6_134504999_134505166	0.35	Lrp6	low density lipoprotein receptor-related protein 6	33789	0.15
chr9_71974657_71974812	0.35	Gm37663	predicted gene, 37663	16537	0.1
chr9_74873778_74874078	0.35	Onecut1	one cut domain, family member 1	7444	0.16
chr10_77379991_77380173	0.35	Adarb1	adenosine deaminase, RNA-specific, B1	9841	0.2
chr1_82258433_82258589	0.35	Gm9747	predicted gene 9747	25399	0.16
chr1_155202064_155202230	0.35	Stx6	syntaxin 6	7126	0.15
chr13_101718024_101718189	0.34	Pik3r1	phosphoinositide-3-kinase regulatory subunit 1	16002	0.21
chr12_70050792_70050966	0.34	Nin	ninein	405	0.82
chr1_167755293_167755461	0.34	Lmx1a	LIM homeobox transcription factor 1 alpha	65820	0.13
chr16_10976433_10976649	0.34	Litaf	LPS-induced TN factor	962	0.41
chr18_65222814_65223030	0.34	Nedd4l	neural precursor cell expressed, developmentally down-regulated gene 4-like	15038	0.15
chr13_38150631_38150801	0.34	Dsp	desmoplakin	578	0.6
chr9_121415708_121416155	0.33	Trak1	trafficking protein, kinesin binding 1	44	0.98
chr3_107850765_107850942	0.33	Gm36211	predicted gene, 36211	17314	0.08
chr7_14428724_14428875	0.33	Sult2a8	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8	7648	0.17
chr7_72998547_72998698	0.33	Gm5335	predicted gene 5335	8469	0.25
chr2_122256897_122257048	0.33	Sord	sorbitol dehydrogenase	22223	0.09
chr2_126916345_126916504	0.33	Sppl2a	signal peptide peptidase like 2A	3921	0.19
chr8_13490011_13490371	0.33	Gas6	growth arrest specific 6	4299	0.18
chr6_136461910_136462080	0.33	Gm6728	predicted gene 6728	25191	0.11
chr1_41543586_41543980	0.33	Gm28634	predicted gene 28634	14240	0.31
chr2_136911982_136912324	0.32	Slx4ip	SLX4 interacting protein	6610	0.18
chr16_57582101_57582276	0.32	Cmss1	cms small ribosomal subunit 1	24588	0.2
chr5_88797033_88797476	0.32	Gm42912	predicted gene 42912	3358	0.19
chr5_17854594_17854745	0.32	Cd36	CD36 molecule	4877	0.33
chr3_69139928_69140109	0.32	Gm1647	predicted gene 1647	8785	0.14
chr4_41527930_41528260	0.32	Fam219a	family with sequence similarity 219, member A	3325	0.13
chr8_46804538_46804714	0.32	Irf2	interferon regulatory factor 2	1698	0.32
chr10_20548960_20549132	0.32	Pde7b	phosphodiesterase 7B	576	0.79
chrX_60288366_60288543	0.32	Atp11c	ATPase, class VI, type 11C	21624	0.19
chr17_24418727_24418886	0.32	Rnps1	RNA binding protein with serine rich domain 1	314	0.75
chr8_35654448_35654627	0.32	Mfhas1	malignant fibrous histiocytoma amplified sequence 1	47260	0.11
chr4_106778453_106778616	0.32	Gm12745	predicted gene 12745	3718	0.18
chr2_45261991_45262163	0.32	Gm13475	predicted gene 13475	67155	0.12
chr4_134067460_134067623	0.32	Crybg2	crystallin beta-gamma domain containing 2	911	0.42
chr17_29123827_29123978	0.31	Rab44	RAB44, member RAS oncogene family	9721	0.09
chr7_48925237_48925540	0.31	Gm18559	predicted gene, 18559	14730	0.13
chr4_104229316_104229674	0.31	Dab1	disabled 1	137618	0.05
chr17_5058324_5058580	0.31	Arid1b	AT rich interactive domain 1B (SWI-like)	17874	0.23
chr17_6197582_6197772	0.31	Tulp4	tubby like protein 4	34975	0.1
chr10_59537699_59537863	0.31	Gm10322	predicted gene 10322	78282	0.08
chr8_27106933_27107116	0.31	Adgra2	adhesion G protein-coupled receptor A2	7109	0.12
chr1_68809984_68810367	0.31	Gm37061	predicted gene, 37061	48448	0.17
chr11_51584565_51584756	0.31	Phykpl	5-phosphohydroxy-L-lysine phospholyase	97	0.95

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead1

View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:2000586	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.1	0.6	GO:0048143	astrocyte activation(GO:0048143)
0.1	0.3	GO:0010986	positive regulation of lipoprotein particle clearance(GO:0010986)
0.1	0.2	GO:1901078	negative regulation of relaxation of muscle(GO:1901078)
0.1	0.3	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1	0.2	GO:2000259	positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.1	0.4	GO:0001835	blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.1	0.2	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.1	0.3	GO:1904354	negative regulation of telomere capping(GO:1904354)
0.1	0.2	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1	0.2	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.1	0.2	GO:0006046	N-acetylglucosamine catabolic process(GO:0006046)
0.0	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.4	GO:0038180	nerve growth factor signaling pathway(GO:0038180)
0.0	0.3	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.2	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.0	0.3	GO:0019368	fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.0	GO:0097252	oligodendrocyte apoptotic process(GO:0097252)
0.0	0.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.2	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.2	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.2	GO:1901164	negative regulation of trophoblast cell migration(GO:1901164)
0.0	0.1	GO:1902956	regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902956)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.1	GO:1903371	regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0	0.1	GO:0001555	oocyte growth(GO:0001555)
0.0	0.1	GO:0045218	zonula adherens maintenance(GO:0045218)
0.0	0.4	GO:1900746	regulation of vascular endothelial growth factor signaling pathway(GO:1900746)
0.0	0.0	GO:1901185	negative regulation of ERBB signaling pathway(GO:1901185)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.2	GO:1900103	positive regulation of endoplasmic reticulum unfolded protein response(GO:1900103)
0.0	0.3	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0051385	response to mineralocorticoid(GO:0051385)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.3	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.1	GO:0071816	protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0	0.1	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.2	GO:0006983	ER overload response(GO:0006983)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0090520	sphingolipid mediated signaling pathway(GO:0090520)
0.0	0.1	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:1902896	terminal web assembly(GO:1902896)
0.0	0.1	GO:0010751	negative regulation of nitric oxide mediated signal transduction(GO:0010751)
0.0	0.1	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.1	GO:0060523	prostate epithelial cord elongation(GO:0060523)
0.0	0.1	GO:0006068	ethanol catabolic process(GO:0006068)
0.0	0.1	GO:0060435	bronchiole development(GO:0060435)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.2	GO:2000392	regulation of lamellipodium morphogenesis(GO:2000392) positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.1	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.1	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.1	GO:1990705	cholangiocyte proliferation(GO:1990705)
0.0	0.1	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.1	GO:0042851	L-alanine metabolic process(GO:0042851)
0.0	0.0	GO:2000698	positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698)
0.0	0.1	GO:0036151	phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.2	GO:0033601	positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0	0.1	GO:0000350	generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0	0.1	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.0	0.1	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.1	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0003213	cardiac right atrium morphogenesis(GO:0003213)
0.0	0.1	GO:0006382	adenosine to inosine editing(GO:0006382)
0.0	0.1	GO:0033313	meiotic cell cycle checkpoint(GO:0033313)
0.0	0.0	GO:0038108	negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0	0.0	GO:0050747	positive regulation of lipoprotein metabolic process(GO:0050747)
0.0	0.3	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.1	GO:0044004	killing by symbiont of host cells(GO:0001907) disruption by symbiont of host cell(GO:0044004)
0.0	0.1	GO:1902309	negative regulation of peptidyl-serine dephosphorylation(GO:1902309)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0046654	tetrahydrofolate biosynthetic process(GO:0046654)
0.0	0.1	GO:0070343	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.1	GO:0035992	tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.0	0.1	GO:0071799	response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0	0.3	GO:0042359	vitamin D metabolic process(GO:0042359)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:2000766	negative regulation of cytoplasmic translation(GO:2000766)
0.0	0.1	GO:0006868	glutamine transport(GO:0006868)
0.0	0.1	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.0	0.1	GO:0071072	negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0	0.1	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0	0.1	GO:0002121	inter-male aggressive behavior(GO:0002121)
0.0	0.2	GO:0097034	mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0	0.0	GO:1902566	regulation of eosinophil degranulation(GO:0043309) regulation of eosinophil activation(GO:1902566)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.2	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.2	GO:0043923	positive regulation by host of viral transcription(GO:0043923)
0.0	0.1	GO:0061146	Peyer's patch morphogenesis(GO:0061146)
0.0	0.1	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.3	GO:0014850	response to muscle activity(GO:0014850)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.1	GO:0090427	activation of meiosis(GO:0090427)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0006545	glycine biosynthetic process(GO:0006545)
0.0	0.1	GO:0043578	nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0032349	positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0	0.1	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.1	GO:0009176	pyrimidine deoxyribonucleoside monophosphate metabolic process(GO:0009176) dUMP metabolic process(GO:0046078)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.1	GO:0034351	negative regulation of glial cell apoptotic process(GO:0034351)
0.0	0.1	GO:0032486	Rap protein signal transduction(GO:0032486)
0.0	0.1	GO:0002604	dendritic cell antigen processing and presentation(GO:0002468) regulation of dendritic cell antigen processing and presentation(GO:0002604) positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0	0.0	GO:0009446	putrescine biosynthetic process(GO:0009446)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.1	GO:0032811	negative regulation of epinephrine secretion(GO:0032811)
0.0	0.2	GO:0090140	regulation of mitochondrial fission(GO:0090140)
0.0	0.1	GO:0097477	lateral motor column neuron migration(GO:0097477)
0.0	0.1	GO:0034312	diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0	0.1	GO:0043589	skin morphogenesis(GO:0043589)
0.0	0.1	GO:0090050	positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0046321	positive regulation of fatty acid oxidation(GO:0046321)
0.0	0.1	GO:0006702	androgen biosynthetic process(GO:0006702)
0.0	0.1	GO:0034975	protein folding in endoplasmic reticulum(GO:0034975)
0.0	0.1	GO:0061099	negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0	0.1	GO:0070836	caveola assembly(GO:0070836)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0031293	membrane protein intracellular domain proteolysis(GO:0031293)
0.0	0.0	GO:0006578	amino-acid betaine biosynthetic process(GO:0006578)
0.0	0.3	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.0	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.0	GO:1904219	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0003192	mitral valve formation(GO:0003192)
0.0	0.0	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.0	0.0	GO:0060154	cellular process regulating host cell cycle in response to virus(GO:0060154)
0.0	0.1	GO:0032328	alanine transport(GO:0032328)
0.0	0.1	GO:0060613	fat pad development(GO:0060613)
0.0	0.0	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.0	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:0015886	heme transport(GO:0015886)
0.0	0.0	GO:0006538	glutamate catabolic process(GO:0006538)
0.0	0.1	GO:0033623	regulation of integrin activation(GO:0033623)
0.0	0.0	GO:0040031	snRNA modification(GO:0040031)
0.0	0.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.0	GO:0032289	central nervous system myelin formation(GO:0032289)
0.0	0.0	GO:0061038	uterus morphogenesis(GO:0061038)
0.0	0.0	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.0	0.0	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.0	GO:0002901	mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0	0.1	GO:0045332	phospholipid translocation(GO:0045332)
0.0	0.0	GO:0010746	regulation of plasma membrane long-chain fatty acid transport(GO:0010746)
0.0	0.0	GO:0021699	cerebellar cortex maturation(GO:0021699)
0.0	0.2	GO:0042754	negative regulation of circadian rhythm(GO:0042754)
0.0	0.0	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.0	GO:0003134	BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0	0.1	GO:0032367	intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0061727	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.0	GO:0015819	lysine transport(GO:0015819)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.3	GO:0048025	negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0	0.1	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.1	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.1	GO:1902992	negative regulation of amyloid precursor protein catabolic process(GO:1902992)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.0	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.2	GO:0001946	lymphangiogenesis(GO:0001946) lymph vessel morphogenesis(GO:0036303)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.0	GO:0042524	negative regulation of tyrosine phosphorylation of Stat5 protein(GO:0042524)
0.0	0.1	GO:0006750	glutathione biosynthetic process(GO:0006750)
0.0	0.1	GO:0006123	mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.6	GO:0042058	regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.0	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.0	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0060586	multicellular organismal iron ion homeostasis(GO:0060586)
0.0	0.0	GO:0043654	recognition of apoptotic cell(GO:0043654)
0.0	0.1	GO:0044828	negative regulation by host of viral genome replication(GO:0044828)
0.0	0.1	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.0	GO:0097680	double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0	0.0	GO:0033210	leptin-mediated signaling pathway(GO:0033210)
0.0	0.1	GO:0032780	negative regulation of ATPase activity(GO:0032780)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:0060060	post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0	0.0	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	0.0	GO:0034287	detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0	0.0	GO:0010727	negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0	0.0	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.2	GO:0016578	histone deubiquitination(GO:0016578)
0.0	0.0	GO:0070278	extracellular matrix constituent secretion(GO:0070278)
0.0	0.1	GO:1901030	positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901030)
0.0	0.0	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0006283	transcription-coupled nucleotide-excision repair(GO:0006283)
0.0	0.0	GO:1900019	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.0	GO:0001757	somite specification(GO:0001757)
0.0	0.2	GO:0032094	response to food(GO:0032094)
0.0	0.0	GO:0043435	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.0	GO:0050955	thermoception(GO:0050955)
0.0	0.1	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.0	0.0	GO:2000019	negative regulation of male gonad development(GO:2000019)
0.0	0.0	GO:0048386	positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.0	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.0	GO:0006549	isoleucine metabolic process(GO:0006549)
0.0	0.0	GO:0035935	androgen secretion(GO:0035935) regulation of androgen secretion(GO:2000834) positive regulation of androgen secretion(GO:2000836)
0.0	0.0	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.1	GO:0043248	proteasome assembly(GO:0043248)
0.0	0.0	GO:0051088	monocyte activation(GO:0042117) PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0033523	histone H2B ubiquitination(GO:0033523)
0.0	0.2	GO:0043968	histone H2A acetylation(GO:0043968)
0.0	0.0	GO:1903332	regulation of protein folding(GO:1903332) positive regulation of protein folding(GO:1903334)
0.0	0.0	GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903799)
0.0	0.0	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.0	GO:0006000	fructose metabolic process(GO:0006000)
0.0	0.0	GO:0072050	S-shaped body morphogenesis(GO:0072050)
0.0	0.1	GO:0048934	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.2	GO:0015804	neutral amino acid transport(GO:0015804)
0.0	0.0	GO:0070120	ciliary neurotrophic factor-mediated signaling pathway(GO:0070120)
0.0	0.1	GO:0002227	innate immune response in mucosa(GO:0002227)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0045098	type III intermediate filament(GO:0045098)
0.1	0.3	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:0097433	dense body(GO:0097433)
0.1	0.3	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.3	GO:0061574	ASAP complex(GO:0061574)
0.0	0.3	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.2	GO:0005947	mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0	0.2	GO:0005915	zonula adherens(GO:0005915)
0.0	0.1	GO:0031092	platelet alpha granule membrane(GO:0031092)
0.0	0.2	GO:0030870	Mre11 complex(GO:0030870)
0.0	0.3	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.2	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.2	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.1	GO:0071818	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.1	GO:0032777	Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0	0.1	GO:1990357	terminal web(GO:1990357)
0.0	0.1	GO:0044299	C-fiber(GO:0044299)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0044611	nuclear pore inner ring(GO:0044611)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.3	GO:0005916	fascia adherens(GO:0005916)
0.0	0.1	GO:0031313	extrinsic component of endosome membrane(GO:0031313)
0.0	0.1	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0005899	insulin receptor complex(GO:0005899)
0.0	0.1	GO:0030868	smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0	0.1	GO:0097452	GAIT complex(GO:0097452)
0.0	0.3	GO:0097038	perinuclear endoplasmic reticulum(GO:0097038)
0.0	0.2	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.1	GO:0070110	ciliary neurotrophic factor receptor complex(GO:0070110)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.1	GO:0070552	BRISC complex(GO:0070552)
0.0	0.1	GO:0005827	polar microtubule(GO:0005827)
0.0	0.0	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0005869	dynactin complex(GO:0005869)
0.0	0.0	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.2	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.3	GO:0030057	desmosome(GO:0030057)
0.0	0.1	GO:0000835	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.2	GO:0042101	T cell receptor complex(GO:0042101)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:1990909	Wnt signalosome(GO:1990909)
0.0	0.1	GO:0097470	ribbon synapse(GO:0097470)
0.0	0.0	GO:0044614	nuclear pore cytoplasmic filaments(GO:0044614)
0.0	0.1	GO:0044327	dendritic spine head(GO:0044327)
0.0	0.0	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.0	GO:0070044	synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.0	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0000164	protein phosphatase type 1 complex(GO:0000164)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1	0.6	GO:0017034	Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.1	0.3	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.2	GO:0043125	ErbB-3 class receptor binding(GO:0043125)
0.1	0.3	GO:0035473	lipase binding(GO:0035473)
0.0	0.1	GO:0008107	galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.3	GO:0009922	fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0	0.1	GO:0042392	sphingosine-1-phosphate phosphatase activity(GO:0042392)
0.0	0.2	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0004699	calcium-independent protein kinase C activity(GO:0004699)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0031871	proteinase activated receptor binding(GO:0031871)
0.0	0.5	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.1	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.2	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.1	GO:0033142	progesterone receptor binding(GO:0033142)
0.0	0.2	GO:0004908	interleukin-1 receptor activity(GO:0004908)
0.0	0.1	GO:0005338	nucleotide-sugar transmembrane transporter activity(GO:0005338)
0.0	0.1	GO:0003726	double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0	0.1	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.2	GO:0047184	1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0	0.2	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0016215	acyl-CoA desaturase activity(GO:0016215)
0.0	0.2	GO:0031419	cobalamin binding(GO:0031419)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:1990254	keratin filament binding(GO:1990254)
0.0	0.1	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.2	GO:0032027	myosin light chain binding(GO:0032027)
0.0	0.1	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.7	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.1	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.4	GO:0034185	apolipoprotein binding(GO:0034185)
0.0	0.1	GO:0070996	type 1 melanocortin receptor binding(GO:0070996)
0.0	0.2	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.2	GO:0016004	phospholipase activator activity(GO:0016004)
0.0	0.1	GO:0016532	superoxide dismutase copper chaperone activity(GO:0016532)
0.0	0.1	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.1	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.2	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.2	GO:0005522	profilin binding(GO:0005522)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.3	GO:0030676	Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0	0.1	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.1	GO:0047391	alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0	0.1	GO:0004332	fructose-bisphosphate aldolase activity(GO:0004332)
0.0	0.1	GO:0000253	3-keto sterol reductase activity(GO:0000253)
0.0	0.1	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.1	GO:0003956	NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.0	GO:0060229	lipase activator activity(GO:0060229)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0035612	AP-2 adaptor complex binding(GO:0035612)
0.0	0.1	GO:0008732	threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.3	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.0	GO:0030284	estrogen receptor activity(GO:0030284)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.1	GO:0010858	calcium-dependent protein kinase regulator activity(GO:0010858)
0.0	0.1	GO:0000900	translation repressor activity, nucleic acid binding(GO:0000900)
0.0	0.3	GO:0043813	phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0	0.0	GO:0070326	very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0	0.1	GO:0008603	cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.0	GO:0003865	3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0	0.1	GO:0004022	alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0	0.3	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.0	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.1	GO:0030235	nitric-oxide synthase regulator activity(GO:0030235)
0.0	0.0	GO:0001226	RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.0	GO:0016635	oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0004949	cannabinoid receptor activity(GO:0004949)
0.0	0.0	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.1	GO:0017162	aryl hydrocarbon receptor binding(GO:0017162)
0.0	0.2	GO:0042975	peroxisome proliferator activated receptor binding(GO:0042975)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0016724	ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0	0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.0	0.1	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0097322	7SK snRNA binding(GO:0097322)
0.0	0.1	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.0	GO:0070052	collagen V binding(GO:0070052)
0.0	0.0	GO:0032564	dATP binding(GO:0032564)
0.0	0.2	GO:0017056	structural constituent of nuclear pore(GO:0017056)
0.0	0.0	GO:0004416	hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0	0.0	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.3	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.0	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.0	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.0	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0031735	CCR10 chemokine receptor binding(GO:0031735)
0.0	0.1	GO:0001618	virus receptor activity(GO:0001618)
0.0	0.1	GO:0004017	adenylate kinase activity(GO:0004017)
0.0	0.0	GO:0015057	thrombin receptor activity(GO:0015057)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.8	PID NECTIN PATHWAY	Nectin adhesion pathway
0.4	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	ST WNT CA2 CYCLIC GMP PATHWAY	Wnt/Ca2+/cyclic GMP signaling.
0.1	PID INTEGRIN A4B1 PATHWAY	Alpha4 beta1 integrin signaling events
0.4	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.2	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	PID PS1 PATHWAY	Presenilin action in Notch and Wnt signaling
0.2	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network
0.0	PID INTEGRIN3 PATHWAY	Beta3 integrin cell surface interactions
0.5	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.4	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.4	PID RAS PATHWAY	Regulation of Ras family activation
0.0	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.2	PID CONE PATHWAY	Visual signal transduction: Cones
0.2	PID HEDGEHOG 2PATHWAY	Signaling events mediated by the Hedgehog family

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.3	REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION	Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.6	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.3	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY	Genes involved in Regulation of the Fanconi anemia pathway
0.2	REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION	Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1	REACTOME BINDING AND ENTRY OF HIV VIRION	Genes involved in Binding and entry of HIV virion
0.2	REACTOME ACYL CHAIN REMODELLING OF PS	Genes involved in Acyl chain remodelling of PS
0.2	REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS	Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.4	REACTOME CA DEPENDENT EVENTS	Genes involved in Ca-dependent events
0.4	REACTOME STEROID HORMONES	Genes involved in Steroid hormones
0.2	REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL	Genes involved in AKT phosphorylates targets in the cytosol
0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.1	REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE	Genes involved in p53-Dependent G1 DNA Damage Response
0.1	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.0	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.1	REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS	Genes involved in Signal regulatory protein (SIRP) family interactions
0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.2	REACTOME GENERATION OF SECOND MESSENGER MOLECULES	Genes involved in Generation of second messenger molecules
0.2	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.4	REACTOME CIRCADIAN CLOCK	Genes involved in Circadian Clock
0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.1	REACTOME PIP3 ACTIVATES AKT SIGNALING	Genes involved in PIP3 activates AKT signaling
0.1	REACTOME PROLACTIN RECEPTOR SIGNALING	Genes involved in Prolactin receptor signaling
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions