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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Tfap2c

Z-value: 1.29

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Transcription factors associated with Tfap2c

Gene Symbol	Gene ID	Gene Info
Tfap2c Ensembl NCBI MGI UniProt	ENSMUSG00000028640.5	transcription factor AP-2, gamma

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr2_172684895_172685060	Tfap2c	132861	0.043166	0.72	1.0e-01	Click!
chr2_172550558_172550733	Tfap2c	8	0.979771	-0.71	1.2e-01	Click!
chr2_172614148_172614317	Tfap2c	62116	0.114609	-0.63	1.8e-01	Click!
chr2_172580659_172580839	Tfap2c	28633	0.180876	0.52	2.9e-01	Click!
chr2_172690322_172690473	Tfap2c	138281	0.040437	0.45	3.7e-01	Click!

Activity of the Tfap2c motif across conditions

Conditions sorted by the z-value of the Tfap2c motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_99104837_99105019	0.93	Tns4	tensin 4	15622	0.14
chr4_138979154_138979535	0.76	Tmco4	transmembrane and coiled-coil domains 4	6435	0.16
chr10_80438140_80438330	0.72	Tcf3	transcription factor 3	4588	0.1
chr7_19952685_19952933	0.67	Rpl7a-ps8	ribosomal protein L7A, pseudogene 8	974	0.29
chr11_52257389_52257568	0.67	Tcf7	transcription factor 7, T cell specific	17399	0.11
chr7_79279429_79279594	0.67	Gm44639	predicted gene 44639	1744	0.27
chr5_99239712_99239874	0.64	Rasgef1b	RasGEF domain family, member 1B	3447	0.29
chr13_28930434_28930607	0.62	Sox4	SRY (sex determining region Y)-box 4	23193	0.17
chr5_144370961_144371328	0.61	Dmrt1i	Dmrt1 interacting ncRNA	12619	0.16
chr18_65989569_65989860	0.60	Lman1	lectin, mannose-binding, 1	3946	0.15
chr14_11619733_11619902	0.60	Ptprg	protein tyrosine phosphatase, receptor type, G	66236	0.11
chr16_8659432_8659599	0.59	Pmm2	phosphomannomutase 2	10923	0.1
chr4_57543982_57544152	0.59	Pakap	paralemmin A kinase anchor protein	24092	0.22
chr5_122459012_122459200	0.58	Anapc7	anaphase promoting complex subunit 7	17731	0.08
chr16_13940553_13940716	0.57	Mpv17l	Mpv17 transgene, kidney disease mutant-like	4	0.96
chr1_169166546_169166738	0.54	Mir6354	microRNA 6354	147553	0.04
chr10_78308725_78308893	0.54	AC160405.1		1190	0.23
chr17_63488193_63488355	0.50	Fbxl17	F-box and leucine-rich repeat protein 17	4479	0.29
chr17_56780401_56780582	0.50	Rfx2	regulatory factor X, 2 (influences HLA class II expression)	3213	0.14
chr5_151060423_151060640	0.49	Stard13	StAR-related lipid transfer (START) domain containing 13	28731	0.19
chr7_46726457_46726608	0.48	Saa4	serum amyloid A 4	6071	0.09
chr16_46010174_46010340	0.48	Plcxd2	phosphatidylinositol-specific phospholipase C, X domain containing 2	39	0.97
chr8_72409462_72409669	0.48	Eps15l1	epidermal growth factor receptor pathway substrate 15-like 1	11873	0.1
chr10_80332281_80332447	0.47	Reep6	receptor accessory protein 6	2162	0.11
chr16_24313632_24313811	0.46	AC169509.1	BMP2 inducible kinase (Bmp2k) pseudogene	23885	0.17
chr2_26153414_26153565	0.46	Tmem250-ps	transmembrane protein 250, pseudogene	12968	0.11
chr11_87732236_87732387	0.45	Rnf43	ring finger protein 43	1609	0.21
chr16_97940453_97940821	0.45	Zbtb21	zinc finger and BTB domain containing 21	12461	0.17
chr4_133561732_133562055	0.45	Gm23158	predicted gene, 23158	2944	0.13
chr18_67448711_67448888	0.44	Afg3l2	AFG3-like AAA ATPase 2	308	0.86
chr19_8987926_8988110	0.44	Ahnak	AHNAK nucleoprotein (desmoyokin)	1266	0.26
chr8_40660395_40660561	0.44	Adam24	a disintegrin and metallopeptidase domain 24 (testase 1)	14599	0.14
chr3_104707896_104708056	0.44	Gm29572	predicted gene 29572	1391	0.27
chr2_172511032_172511203	0.43	Gm14303	predicted gene 14303	1426	0.37
chr2_27042057_27042419	0.42	Gm13398	predicted gene 13398	4953	0.11
chr10_84872038_84872201	0.42	Rfx4	regulatory factor X, 4 (influences HLA class II expression)	33971	0.16
chr18_45575250_45575614	0.42	Kcnn2	potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2	812	0.69
chr1_74807002_74807292	0.42	Wnt10a	wingless-type MMTV integration site family, member 10A	13784	0.11
chr5_33657811_33658158	0.41	Tmem129	transmembrane protein 129	85	0.57
chr19_55463767_55463937	0.41	Vti1a	vesicle transport through interaction with t-SNAREs 1A	82838	0.1
chr7_46849448_46849605	0.41	Ldha	lactate dehydrogenase A	539	0.6
chr7_145047841_145048023	0.40	Ccnd1	cyclin D1	108007	0.05
chr19_10596220_10596418	0.37	Tkfc	triokinase, FMN cyclase	7939	0.09
chr5_34527351_34527633	0.37	Sh3bp2	SH3-domain binding protein 2	1646	0.22
chr9_108400984_108401135	0.37	1700102P08Rik	RIKEN cDNA 1700102P08 gene	8225	0.07
chr7_143614809_143614986	0.37	Tnfrsf26	tumor necrosis factor receptor superfamily, member 26	13056	0.09
chr11_8629102_8629275	0.36	Tns3	tensin 3	4301	0.35
chr11_35930971_35931124	0.36	Wwc1	WW, C2 and coiled-coil domain containing 1	49480	0.14
chr4_131924003_131924348	0.36	Tmem200b	transmembrane protein 200B	2404	0.15
chr7_99168829_99169197	0.36	Dgat2	diacylglycerol O-acyltransferase 2	1093	0.4
chr11_103689147_103689298	0.35	Gosr2	golgi SNAP receptor complex member 2	8472	0.13
chr5_30523230_30523387	0.35	Gm42765	predicted gene 42765	6149	0.14
chr12_100996285_100996501	0.34	Gm36756	predicted gene, 36756	3421	0.16
chr6_86263585_86263762	0.34	Gm43917	predicted gene, 43917	241	0.9
chr19_10065348_10065653	0.34	Fads2	fatty acid desaturase 2	5687	0.14
chr3_104670885_104671048	0.33	Gm29560	predicted gene 29560	956	0.37
chr5_118664076_118664234	0.33	Gm43274	predicted gene 43274	19782	0.14
chr4_152232556_152232715	0.33	Gm13096	predicted gene 13096	28709	0.1
chr12_104992554_104993025	0.33	Syne3	spectrin repeat containing, nuclear envelope family member 3	5888	0.13
chr2_163481751_163481907	0.32	Fitm2	fat storage-inducing transmembrane protein 2	9200	0.11
chr5_25019324_25019486	0.32	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	23652	0.16
chr6_90772172_90772486	0.32	Iqsec1	IQ motif and Sec7 domain 1	8188	0.18
chr1_95317084_95317247	0.32	Fam174a	family with sequence similarity 174, member A	3537	0.27
chr4_152062432_152062592	0.32	Plekhg5	pleckstrin homology domain containing, family G (with RhoGef domain) member 5	9986	0.11
chr2_166100923_166101091	0.31	Sulf2	sulfatase 2	22888	0.16
chr16_34110699_34110875	0.31	Kalrn	kalirin, RhoGEF kinase	13697	0.26
chr6_139588514_139588690	0.31	Pik3c2g	phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma	1365	0.44
chr2_148022052_148022231	0.31	9030622O22Rik	RIKEN cDNA 9030622O22 gene	16129	0.17
chr9_108765050_108765207	0.31	Prkar2a	protein kinase, cAMP dependent regulatory, type II alpha	16883	0.09
chr10_81320539_81320949	0.31	Cactin	cactin, spliceosome C complex subunit	359	0.64
chr13_55450624_55450785	0.30	Mir6943	microRNA 6943	2402	0.13
chr11_69415319_69415489	0.30	Kdm6b	KDM1 lysine (K)-specific demethylase 6B	1729	0.17
chr9_65391751_65391920	0.30	Kbtbd13	kelch repeat and BTB (POZ) domain containing 13	183	0.89
chr9_9188372_9188561	0.30	Gm16833	predicted gene, 16833	47822	0.15
chr11_102401993_102402497	0.30	Slc25a39	solute carrier family 25, member 39	2248	0.14
chr1_191026198_191026354	0.30	Flvcr1	feline leukemia virus subgroup C cellular receptor 1	118	0.89
chr17_29046089_29046300	0.29	Srsf3	serine and arginine-rich splicing factor 3	6500	0.09
chr2_18957058_18957209	0.29	Pip4k2a	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha	40993	0.15
chr18_37997513_37997702	0.29	Arap3	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3	33	0.95
chr7_126280513_126280705	0.28	Sbk1	SH3-binding kinase 1	7209	0.12
chr8_119445523_119446899	0.28	Necab2	N-terminal EF-hand calcium binding protein 2	508	0.74
chr18_80261215_80262161	0.28	Slc66a2	solute carrier family 66 member 2	1152	0.35
chr8_125337571_125337768	0.28	Gm16237	predicted gene 16237	110346	0.06
chr1_134955895_134956232	0.28	Ppp1r12b	protein phosphatase 1, regulatory subunit 12B	121	0.96
chr5_32092059_32092277	0.28	Babam2	BRISC and BRCA1 A complex member 2	12471	0.17
chr16_22895393_22895557	0.28	Ahsg	alpha-2-HS-glycoprotein	611	0.52
chr18_38494979_38495150	0.28	Gm50349	predicted gene, 50349	13761	0.17
chr12_104863757_104863919	0.27	Clmn	calmin	1171	0.39
chr1_178600841_178601326	0.27	Gm24405	predicted gene, 24405	35822	0.18
chr1_38127167_38127331	0.27	Rev1	REV1, DNA directed polymerase	1052	0.49
chr1_90967653_90967817	0.27	Rab17	RAB17, member RAS oncogene family	68	0.96
chr10_121486376_121486686	0.27	Gm40787	predicted gene, 40787	2455	0.18
chr7_71216875_71217198	0.26	6030442E23Rik	RIKEN cDNA 6030442E23 gene	13	0.98
chr10_93641039_93641238	0.26	Ntn4	netrin 4	89	0.96
chr1_194482432_194482667	0.26	Plxna2	plexin A2	135669	0.05
chr12_103995803_103995968	0.26	Gm28577	predicted gene 28577	694	0.52
chr4_136172527_136172687	0.26	E2f2	E2F transcription factor 2	213	0.91
chr15_73791838_73792025	0.26	Ndufb4c	NADH:ubiquinone oxidoreductase subunit B4C	17965	0.15
chr5_65435787_65435980	0.26	Ugdh	UDP-glucose dehydrogenase	66	0.94
chr10_127576673_127576991	0.26	Lrp1	low density lipoprotein receptor-related protein 1	5053	0.12
chr7_49351868_49352264	0.26	Gm44913	predicted gene 44913	5972	0.24
chr8_11005778_11005929	0.26	9530052E02Rik	RIKEN cDNA 9530052E02 gene	1997	0.22
chr13_73767873_73768041	0.25	Slc12a7	solute carrier family 12, member 7	4218	0.2
chr5_145222977_145223149	0.25	Zfp655	zinc finger protein 655	8652	0.1
chr4_123282595_123282770	0.25	Pabpc4	poly(A) binding protein, cytoplasmic 4	143	0.91
chr19_44418157_44418318	0.25	Gm50337	predicted gene, 50337	1373	0.35
chr11_120316158_120316318	0.25	Bahcc1	BAH domain and coiled-coil containing 1	26445	0.07
chr5_62622955_62623325	0.25	Gm43237	predicted gene 43237	9682	0.2
chr4_32250961_32251192	0.25	Bach2it1	BTB and CNC homology 2, intronic transcript 1	685	0.69
chrX_20635839_20636020	0.25	Rbm10	RNA binding motif protein 10	15831	0.11
chr3_108297146_108297319	0.25	Gm43099	predicted gene 43099	9351	0.09
chr1_133877032_133877215	0.24	Optc	opticin	24204	0.12
chr4_46304170_46304340	0.24	Gm12447	predicted gene 12447	23041	0.12
chr5_120514357_120514577	0.24	Slc8b1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	1324	0.29
chr17_25863718_25863900	0.24	Mcrip2	MAPK regulated corepressor interacting protein 2	459	0.51
chr7_105737131_105737562	0.24	Rrp8	ribosomal RNA processing 8, methyltransferase, homolog (yeast)	39	0.72
chr6_72142695_72142867	0.24	4933431G14Rik	RIKEN cDNA 4933431G14 gene	19584	0.11
chr9_80688608_80688774	0.24	Gm39380	predicted gene, 39380	21304	0.24
chr13_17805107_17805599	0.24	Cdk13	cyclin-dependent kinase 13	256	0.88
chr16_18776692_18776858	0.24	Cldn5	claudin 5	72	0.96
chr8_47713134_47713303	0.24	E030037K01Rik	RIKEN cDNA E030037K01 gene	48	0.91
chr5_110431894_110432052	0.23	Fbrsl1	fibrosin-like 1	1348	0.35
chr11_117778128_117778307	0.23	Tmc6	transmembrane channel-like gene family 6	1431	0.22
chr12_111450305_111450614	0.23	Tnfaip2	tumor necrosis factor, alpha-induced protein 2	60	0.96
chr10_30000969_30001164	0.23	Gm48215	predicted gene, 48215	366	0.89
chr9_44718034_44718200	0.23	Phldb1	pleckstrin homology like domain, family B, member 1	1737	0.17
chr19_7294990_7295178	0.23	Mark2	MAP/microtubule affinity regulating kinase 2	363	0.77
chr9_110316019_110316191	0.23	Elp6	elongator acetyltransferase complex subunit 6	6458	0.11
chr8_121950086_121950249	0.23	Banp	BTG3 associated nuclear protein	325	0.56
chr4_106440974_106441125	0.23	Usp24	ubiquitin specific peptidase 24	12556	0.15
chr17_45567292_45567749	0.22	Hsp90ab1	heat shock protein 90 alpha (cytosolic), class B member 1	2216	0.14
chr13_54462200_54462359	0.22	Thoc3	THO complex 3	6509	0.16
chr9_61319859_61320021	0.22	B930092H01Rik	RIKEN cDNA B930092H01 gene	26131	0.17
chr1_75191952_75192286	0.22	Ankzf1	ankyrin repeat and zinc finger domain containing 1	32	0.52
chr4_135241723_135242067	0.22	Clic4	chloride intracellular channel 4 (mitochondrial)	30919	0.12
chr8_68083083_68083240	0.22	Psd3	pleckstrin and Sec7 domain containing 3	20875	0.24
chr11_107342418_107342585	0.22	Gm11716	predicted gene 11716	4451	0.16
chr11_70539975_70540306	0.22	Pld2	phospholipase D2	76	0.82
chrX_129749622_129749793	0.22	Diaph2	diaphanous related formin 2	35	0.99
chr7_101393766_101393917	0.22	Arap1	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1	527	0.67
chr1_60662412_60662596	0.22	Gm11577	predicted gene 11577	38368	0.1
chr5_3466112_3466325	0.21	Cdk6	cyclin-dependent kinase 6	4731	0.16
chr9_103365880_103366048	0.21	Cdv3	carnitine deficiency-associated gene expressed in ventricle 3	124	0.95
chr17_30611479_30611666	0.21	Glo1	glyoxalase 1	997	0.37
chr11_16739244_16739507	0.21	Gm25698	predicted gene, 25698	6664	0.2
chr7_80642020_80642180	0.21	Gm15880	predicted gene 15880	6083	0.17
chr7_12997356_12997531	0.21	Slc27a5	solute carrier family 27 (fatty acid transporter), member 5	234	0.8
chr19_4441877_4442205	0.21	A930001C03Rik	RIKEN cDNA A930001C03 gene	1697	0.23
chr7_141193568_141193999	0.21	Hras	Harvey rat sarcoma virus oncogene	99	0.77
chr6_88761318_88761481	0.21	Gm43999	predicted gene, 43999	18672	0.11
chr7_64357520_64357685	0.21	Gm20457	predicted gene 20457	11638	0.13
chr11_114864022_114864192	0.21	Gprc5c	G protein-coupled receptor, family C, group 5, member C	385	0.8
chr14_25181416_25181581	0.21	4930572O13Rik	RIKEN cDNA 4930572O13 gene	38257	0.14
chr4_113008669_113008831	0.21	Gm12818	predicted gene 12818	28937	0.2
chr1_164458750_164458928	0.21	Atp1b1	ATPase, Na+/K+ transporting, beta 1 polypeptide	484	0.74
chr7_28982367_28982605	0.21	Map4k1	mitogen-activated protein kinase kinase kinase kinase 1	342	0.62
chr17_15192816_15193078	0.20	Gm35455	predicted gene, 35455	40788	0.13
chr4_53595620_53595787	0.20	Slc44a1	solute carrier family 44, member 1	402	0.85
chr17_12769492_12769649	0.20	Igf2r	insulin-like growth factor 2 receptor	94	0.95
chr13_56645697_56645857	0.20	Tgfbi	transforming growth factor, beta induced	14564	0.19
chr4_140621608_140621759	0.20	Arhgef10l	Rho guanine nucleotide exchange factor (GEF) 10-like	4618	0.21
chr3_108287816_108288159	0.20	Gm43099	predicted gene 43099	106	0.92
chr14_74732078_74732418	0.20	Esd	esterase D/formylglutathione hydrolase	49	0.98
chr9_53323560_53323724	0.20	Exph5	exophilin 5	17442	0.18
chr9_15058478_15058644	0.19	Panx1	pannexin 1	13083	0.18
chr8_83580805_83581141	0.19	Gm45823	predicted gene 45823	4552	0.1
chr2_58551945_58552231	0.19	Acvr1	activin A receptor, type 1	13650	0.2
chr11_104463246_104463405	0.19	Kansl1	KAT8 regulatory NSL complex subunit 1	4666	0.18
chr7_25706856_25707106	0.19	Ccdc97	coiled-coil domain containing 97	9125	0.09
chr7_28867783_28867955	0.19	Lgals7	lectin, galactose binding, soluble 7	3414	0.11
chr12_86883907_86884153	0.19	Irf2bpl	interferon regulatory factor 2 binding protein-like	768	0.64
chr13_41486979_41487189	0.19	Gm32401	predicted gene, 32401	46	0.65
chr10_79865745_79866064	0.19	Plppr3	phospholipid phosphatase related 3	1377	0.14
chr19_8251883_8252162	0.19	Gm41804	predicted gene, 41804	54	0.97
chr15_78468233_78468783	0.19	Tmprss6	transmembrane serine protease 6	93	0.94
chr8_106135686_106136171	0.19	1810019D21Rik	RIKEN cDNA 1810019D21 gene	493	0.53
chr2_160840069_160840298	0.19	Gm11447	predicted gene 11447	5430	0.16
chr3_104279647_104279910	0.18	Magi3	membrane associated guanylate kinase, WW and PDZ domain containing 3	59404	0.07
chr8_115649918_115650129	0.18	Gm15655	predicted gene 15655	55055	0.12
chr3_61363955_61364286	0.18	B430305J03Rik	RIKEN cDNA B430305J03 gene	1831	0.25
chr1_153501584_153501799	0.18	Dhx9	DEAH (Asp-Glu-Ala-His) box polypeptide 9	14031	0.16
chr9_14275987_14276328	0.18	Sesn3	sestrin 3	144	0.95
chr6_3182898_3183288	0.18	Gm42642	predicted gene 42642	109	0.95
chr11_98774757_98774908	0.18	Nr1d1	nuclear receptor subfamily 1, group D, member 1	501	0.64
chr14_20929184_20929360	0.18	Vcl	vinculin	126	0.97
chr16_10347675_10347844	0.18	Gm1600	predicted gene 1600	168	0.94
chr8_90908060_90908476	0.17	Gm6658	predicted gene 6658	147	0.73
chr1_191450665_191450840	0.17	Gm32200	predicted gene, 32200	14296	0.14
chr19_4232043_4232236	0.17	Pold4	polymerase (DNA-directed), delta 4	153	0.85
chr11_16815536_16815687	0.17	Egfros	epidermal growth factor receptor, opposite strand	15091	0.21
chr4_149416520_149416730	0.17	Ube4b	ubiquitination factor E4B	9280	0.13
chr5_137501838_137501997	0.17	Pop7	processing of precursor 7, ribonuclease P family, (S. cerevisiae)	508	0.45
chr14_52278932_52279090	0.17	Tox4	TOX high mobility group box family member 4	135	0.61
chr10_79689120_79689284	0.17	Gzmm	granzyme M (lymphocyte met-ase 1)	182	0.86
chr19_6349216_6349557	0.17	Map4k2	mitogen-activated protein kinase kinase kinase kinase 2	1523	0.17
chr10_128981137_128981300	0.17	Olfr9	olfactory receptor 9	8213	0.09
chr8_46491538_46491689	0.17	Acsl1	acyl-CoA synthetase long-chain family member 1	639	0.67
chr17_73995980_73996146	0.16	Gm24475	predicted gene, 24475	4797	0.19
chr9_54843787_54843973	0.16	Rab7-ps1	RAB7, member RAS oncogene family, pseudogene 1	18598	0.15
chr11_50354656_50355246	0.16	Cby3	chibby family member 3	489	0.68

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2c

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.1	0.4	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.1	0.3	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.1	0.3	GO:0019244	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	0.3	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.1	0.2	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.1	0.2	GO:1903142	positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1	0.2	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.1	0.2	GO:2000412	thymocyte migration(GO:0072679) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.0	0.2	GO:0035426	extracellular matrix-cell signaling(GO:0035426)
0.0	0.2	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.1	GO:0046951	ketone body biosynthetic process(GO:0046951)
0.0	0.1	GO:0007223	Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0	0.1	GO:0042276	error-prone translesion synthesis(GO:0042276)
0.0	0.2	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.2	GO:0046015	regulation of transcription by glucose(GO:0046015)
0.0	0.1	GO:0061624	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.1	GO:0060398	regulation of growth hormone receptor signaling pathway(GO:0060398)
0.0	0.2	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:1903061	positive regulation of protein lipidation(GO:1903061)
0.0	0.1	GO:1903911	positive regulation of receptor clustering(GO:1903911)
0.0	0.1	GO:0097195	pilomotor reflex(GO:0097195)
0.0	0.1	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.0	0.2	GO:2000630	positive regulation of miRNA metabolic process(GO:2000630)
0.0	0.1	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.1	GO:2000623	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0	0.2	GO:0015871	choline transport(GO:0015871)
0.0	0.2	GO:1904262	negative regulation of TORC1 signaling(GO:1904262)
0.0	0.1	GO:0046726	positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0034214	protein hexamerization(GO:0034214)
0.0	0.1	GO:0010871	negative regulation of receptor biosynthetic process(GO:0010871)
0.0	0.1	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.2	GO:0006654	phosphatidic acid biosynthetic process(GO:0006654)
0.0	0.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.2	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.1	GO:0045714	low-density lipoprotein particle receptor biosynthetic process(GO:0045713) regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045714)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.2	GO:0043951	negative regulation of cAMP-mediated signaling(GO:0043951)
0.0	0.1	GO:0072180	mesonephric duct morphogenesis(GO:0072180)
0.0	0.2	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0000320	re-entry into mitotic cell cycle(GO:0000320)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.2	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.3	GO:0009226	nucleotide-sugar biosynthetic process(GO:0009226)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.1	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.1	GO:0046826	negative regulation of protein export from nucleus(GO:0046826)
0.0	0.1	GO:0019276	UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0	0.1	GO:0019243	methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0	0.1	GO:0015744	succinate transport(GO:0015744)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0021538	epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0	0.2	GO:0022027	interkinetic nuclear migration(GO:0022027)
0.0	0.1	GO:0051105	regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0	0.1	GO:0015817	histidine transport(GO:0015817)
0.0	0.1	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.1	GO:0021555	midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.0	GO:0038027	apolipoprotein A-I-mediated signaling pathway(GO:0038027)
0.0	0.1	GO:2000054	negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0	0.1	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:0007089	traversing start control point of mitotic cell cycle(GO:0007089)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.2	GO:0008300	isoprenoid catabolic process(GO:0008300)
0.0	0.1	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.2	GO:0070816	phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.0	0.0	GO:0006363	termination of RNA polymerase I transcription(GO:0006363)
0.0	0.0	GO:0060750	epithelial cell proliferation involved in mammary gland duct elongation(GO:0060750)
0.0	0.0	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0046060	dATP metabolic process(GO:0046060)
0.0	0.1	GO:0090188	negative regulation of pancreatic juice secretion(GO:0090188)
0.0	0.1	GO:0002636	positive regulation of germinal center formation(GO:0002636)
0.0	0.1	GO:0002326	B cell lineage commitment(GO:0002326)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.0	GO:0033387	putrescine biosynthetic process from ornithine(GO:0033387)
0.0	0.0	GO:0090170	regulation of Golgi inheritance(GO:0090170)
0.0	0.0	GO:0031914	negative regulation of synaptic plasticity(GO:0031914)
0.0	0.2	GO:0090136	epithelial cell-cell adhesion(GO:0090136)
0.0	0.1	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.0	0.0	GO:1904293	negative regulation of ERAD pathway(GO:1904293)
0.0	0.0	GO:0072092	ureteric bud invasion(GO:0072092)
0.0	0.1	GO:0042045	epithelial fluid transport(GO:0042045)
0.0	0.0	GO:2000667	positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0	0.1	GO:0031115	negative regulation of microtubule polymerization(GO:0031115)
0.0	0.1	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.1	GO:0071218	cellular response to misfolded protein(GO:0071218)
0.0	0.0	GO:0032290	peripheral nervous system myelin formation(GO:0032290)
0.0	0.1	GO:0060839	endothelial cell fate commitment(GO:0060839)
0.0	0.0	GO:0010748	negative regulation of plasma membrane long-chain fatty acid transport(GO:0010748)
0.0	0.0	GO:0009158	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0040016	embryonic cleavage(GO:0040016)
0.0	0.0	GO:0071895	odontoblast differentiation(GO:0071895)
0.0	0.0	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.0	GO:1903660	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.0	GO:0014053	negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0	0.1	GO:0034244	negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0	0.0	GO:0010032	meiotic chromosome condensation(GO:0010032)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.0	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.1	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.2	GO:0030970	retrograde protein transport, ER to cytosol(GO:0030970)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0005745	m-AAA complex(GO:0005745)
0.0	0.1	GO:0043625	delta DNA polymerase complex(GO:0043625)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.2	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0	0.2	GO:0061700	GATOR2 complex(GO:0061700)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.1	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.1	GO:0032021	NELF complex(GO:0032021)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0034448	EGO complex(GO:0034448) Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0033553	rDNA heterochromatin(GO:0033553)
0.0	0.1	GO:0005955	calcineurin complex(GO:0005955)
0.0	0.2	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.4	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0012507	ER to Golgi transport vesicle membrane(GO:0012507)
0.0	0.0	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.0	0.2	GO:0033270	paranode region of axon(GO:0033270)
0.0	0.2	GO:0005641	nuclear envelope lumen(GO:0005641)
0.0	0.1	GO:0005890	sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0	0.1	GO:0044232	organelle membrane contact site(GO:0044232)
0.0	0.2	GO:0098799	outer mitochondrial membrane protein complex(GO:0098799)
0.0	0.1	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.2	GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex(GO:0019908)
0.0	0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.1	GO:1990124	messenger ribonucleoprotein complex(GO:1990124)
0.0	0.1	GO:0031588	nucleotide-activated protein kinase complex(GO:0031588)
0.0	0.3	GO:0005790	smooth endoplasmic reticulum(GO:0005790)
0.0	0.1	GO:0000788	nuclear nucleosome(GO:0000788)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.1	GO:0036513	Derlin-1 retrotranslocation complex(GO:0036513)
0.0	0.0	GO:0035859	Seh1-associated complex(GO:0035859)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.3	GO:0055038	recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.3	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:1990829	C-rich single-stranded DNA binding(GO:1990829)
0.0	0.2	GO:0043237	laminin-1 binding(GO:0043237)
0.0	0.2	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0	0.1	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.0	0.3	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	0.2	GO:1904264	ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0	0.1	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.1	GO:0070644	vitamin D response element binding(GO:0070644)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0051525	NFAT protein binding(GO:0051525)
0.0	0.1	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0	0.3	GO:0004467	long-chain fatty acid-CoA ligase activity(GO:0004467)
0.0	0.1	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.2	GO:0035005	1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0	0.1	GO:0048408	epidermal growth factor binding(GO:0048408)
0.0	0.1	GO:0043814	CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0015037	peptide disulfide oxidoreductase activity(GO:0015037)
0.0	0.3	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.1	GO:0019808	polyamine binding(GO:0019808)
0.0	0.1	GO:0015141	succinate transmembrane transporter activity(GO:0015141)
0.0	0.1	GO:0070915	lysophosphatidic acid receptor activity(GO:0070915)
0.0	0.1	GO:0016361	activin receptor activity, type I(GO:0016361)
0.0	0.2	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.1	GO:0005483	soluble NSF attachment protein activity(GO:0005483)
0.0	0.3	GO:0008143	poly(A) binding(GO:0008143)
0.0	0.1	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0	0.2	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0	0.1	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	0.1	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0004470	malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.0	0.1	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.0	0.2	GO:0023026	MHC class II protein complex binding(GO:0023026)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.3	GO:0043325	phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.0	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.0	0.0	GO:0016309	1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0	0.1	GO:0004679	AMP-activated protein kinase activity(GO:0004679)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0008420	CTD phosphatase activity(GO:0008420)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0019912	cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.0	0.1	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0	0.0	GO:0003941	L-serine ammonia-lyase activity(GO:0003941)
0.0	0.1	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0001222	transcription corepressor binding(GO:0001222)
0.0	0.1	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	0.2	GO:0016854	racemase and epimerase activity(GO:0016854)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	0.0	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.0	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0031559	oxidosqualene cyclase activity(GO:0031559)
0.0	0.2	GO:0008353	RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0	0.1	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.0	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.0	0.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.0	GO:0043120	tumor necrosis factor binding(GO:0043120)
0.0	0.0	GO:0008310	single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.0	GO:0043546	molybdopterin cofactor binding(GO:0043546)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.1	GO:0003841	1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0	0.0	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	0.0	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.0	GO:0032564	dATP binding(GO:0032564)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID NFAT 3PATHWAY	Role of Calcineurin-dependent NFAT signaling in lymphocytes
0.0	0.4	SA REG CASCADE OF CYCLIN EXPR	Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0	0.3	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	0.6	PID RHOA REG PATHWAY	Regulation of RhoA activity
0.0	0.2	PID TCR RAS PATHWAY	Ras signaling in the CD4+ TCR pathway
0.0	0.1	SA G1 AND S PHASES	Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0	0.1	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.0	0.1	PID ERB GENOMIC PATHWAY	Validated nuclear estrogen receptor beta network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.3	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.2	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.3	REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX	Genes involved in CDC6 association with the ORC:origin complex
0.2	REACTOME ALPHA LINOLENIC ACID ALA METABOLISM	Genes involved in alpha-linolenic acid (ALA) metabolism
0.3	REACTOME P38MAPK EVENTS	Genes involved in p38MAPK events
0.3	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.3	REACTOME SYNTHESIS OF PA	Genes involved in Synthesis of PA
0.3	REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE	Genes involved in Synthesis of PIPs at the plasma membrane
0.4	REACTOME NETRIN1 SIGNALING	Genes involved in Netrin-1 signaling
0.1	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1	REACTOME PURINE SALVAGE	Genes involved in Purine salvage

Results for Tfap2c

Z-value: 1.29

Motif logo

Transcription factors associated with Tfap2c

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tfap2c motif across conditions

Conditions sorted by the z-value of the Tfap2c motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2c

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: