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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Tfap2d

Z-value: 2.37

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Transcription factors associated with Tfap2d

Gene Symbol	Gene ID	Gene Info
Tfap2d Ensembl NCBI MGI UniProt	ENSMUSG00000042596.7	transcription factor AP-2, delta

Activity of the Tfap2d motif across conditions

Conditions sorted by the z-value of the Tfap2d motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr9_48735314_48735473	2.51	Zbtb16	zinc finger and BTB domain containing 16	100552	0.07
chr9_48984872_48985421	2.15	Usp28	ubiquitin specific peptidase 28	229	0.92
chr4_98395531_98395682	1.55	Patj	PATJ, crumbs cell polarity complex component	179	0.94
chr11_116413032_116413183	1.49	Rnf157	ring finger protein 157	75	0.95
chr9_21244539_21244737	1.21	Gm48303	predicted gene, 48303	3075	0.11
chr16_22009665_22009878	1.09	Senp2	SUMO/sentrin specific peptidase 2	28	0.97
chr17_47593664_47594464	1.03	Ccnd3	cyclin D3	249	0.86
chr8_95142522_95142681	0.94	Kifc3	kinesin family member C3	54	0.96
chr17_66519289_66519440	0.80	Rab12	RAB12, member RAS oncogene family	13	0.98
chr7_143502466_143502878	0.80	Phlda2	pleckstrin homology like domain, family A, member 2	131	0.93
chr7_126200154_126200345	0.79	Xpo6	exportin 6	93	0.95
chr8_69902037_69902491	0.72	Tssk6	testis-specific serine kinase 6	80	0.69
chr13_9277334_9277485	0.71	Dip2c	disco interacting protein 2 homolog C	427	0.75
chr12_8786836_8787027	0.71	Sdc1	syndecan 1	15128	0.17
chr4_153957077_153957238	0.70	A430005L14Rik	RIKEN cDNA A430005L14 gene	80	0.95
chrY_90783982_90784262	0.66	Gm47283	predicted gene, 47283	616	0.72
chr19_42779893_42780058	0.65	Hps1	HPS1, biogenesis of lysosomal organelles complex 3 subunit 1	1	0.95
chr7_64872491_64872865	0.65	Nsmce3	NSE3 homolog, SMC5-SMC6 complex component	319	0.91
chr8_53511862_53512333	0.64	Aga	aspartylglucosaminidase	299	0.9
chrX_9272438_9272819	0.63	Xk	X-linked Kx blood group	128	0.94
chr12_73908540_73908706	0.63	Hif1a	hypoxia inducible factor 1, alpha subunit	719	0.64
chr11_59306477_59306924	0.63	Wnt9a	wingless-type MMTV integration site family, member 9A	228	0.89
chr2_154604752_154604906	0.61	Pxmp4	peroxisomal membrane protein 4	1121	0.33
chr10_81421035_81421463	0.61	Mir1191b	microRNA 1191b	4952	0.07
chr5_130063906_130064176	0.60	Tpst1	protein-tyrosine sulfotransferase 1	9285	0.13
chr4_40722706_40722857	0.59	Mir207	microRNA 207	136	0.49
chr4_53440897_53441048	0.58	Slc44a1	solute carrier family 44, member 1	288	0.93
chr19_10018064_10018231	0.57	Rab3il1	RAB3A interacting protein (rabin3)-like 1	46	0.96
chr8_127064425_127064598	0.57	Pard3	par-3 family cell polarity regulator	164	0.95
chr1_87756204_87756384	0.56	Atg16l1	autophagy related 16-like 1 (S. cerevisiae)	201	0.92
chr15_63997749_63997925	0.56	Fam49b	family with sequence similarity 49, member B	132	0.96
chr13_55445821_55446370	0.56	Grk6	G protein-coupled receptor kinase 6	634	0.5
chr4_108780712_108780909	0.55	Zfyve9	zinc finger, FYVE domain containing 9	12	0.97
chr2_152293705_152293868	0.54	Tbc1d20	TBC1 domain family, member 20	42	0.96
chr11_61342814_61342965	0.54	Slc47a2	solute carrier family 47, member 2	29	0.97
chr2_167015435_167015605	0.54	Ddx27	DEAD (Asp-Glu-Ala-Asp) box polypeptide 27	210	0.88
chr8_35387028_35387898	0.54	Ppp1r3b	protein phosphatase 1, regulatory subunit 3B	10803	0.16
chr9_72111532_72111696	0.53	Tcf12	transcription factor 12	14	0.96
chr14_31830654_31831034	0.53	Ankrd28	ankyrin repeat domain 28	193	0.95
chr15_28181897_28182071	0.52	Gm49234	predicted gene, 49234	10138	0.17
chr4_32950872_32951028	0.52	Ankrd6	ankyrin repeat domain 6	109	0.96
chr9_48733919_48734091	0.52	Zbtb16	zinc finger and BTB domain containing 16	101940	0.07
chr16_36875280_36875431	0.52	Golgb1	golgi autoantigen, golgin subfamily b, macrogolgin 1	153	0.48
chr17_66077011_66077179	0.52	Ankrd12	ankyrin repeat domain 12	6	0.96
chr3_25144164_25144323	0.51	Naaladl2	N-acetylated alpha-linked acidic dipeptidase-like 2	18	0.69
chr1_151345382_151345687	0.50	Gm10138	predicted gene 10138	303	0.79
chr9_110244718_110245027	0.49	Cspg5	chondroitin sulfate proteoglycan 5	611	0.62
chr3_97681273_97681802	0.48	Gm17651	predicted gene, 17651	6843	0.13
chr18_67289715_67290079	0.47	Impa2	inositol (myo)-1(or 4)-monophosphatase 2	645	0.67
chr10_119239347_119239505	0.46	Cand1	cullin associated and neddylation disassociated 1	123	0.97
chr18_23954548_23954747	0.46	Zfp397	zinc finger protein 397	45	0.96
chr9_105494766_105494934	0.45	Atp2c1	ATPase, Ca++-sequestering	186	0.94
chr12_110850378_110850529	0.45	Zfp839	zinc finger protein 839	147	0.91
chr7_45466341_45466701	0.45	Bax	BCL2-associated X protein	254	0.73
chr17_83706385_83706725	0.44	Mta3	metastasis associated 3	364	0.91
chr5_99252774_99253080	0.44	Rasgef1b	RasGEF domain family, member 1B	0	0.98
chr8_35826198_35826406	0.44	Cldn23	claudin 23	257	0.91
chr10_71344542_71344723	0.43	Cisd1	CDGSH iron sulfur domain 1	322	0.84
chr11_102767137_102767309	0.43	Adam11	a disintegrin and metallopeptidase domain 11	2544	0.18
chr7_51862019_51862194	0.43	Gas2	growth arrest specific 2	91	0.6
chr2_164746193_164746344	0.43	Dnttip1	deoxynucleotidyltransferase, terminal, interacting protein 1	237	0.56
chr9_62340934_62341117	0.43	Anp32a	acidic (leucine-rich) nuclear phosphoprotein 32 family, member A	268	0.92
chr15_36680500_36681039	0.42	Gm10385	predicted gene 10385	9334	0.14
chr1_187608439_187608751	0.42	Esrrg	estrogen-related receptor gamma	196	0.95
chr10_114801635_114801834	0.42	Gm15723	predicted gene 15723	8	0.86
chr6_88044983_88045149	0.42	Rab7	RAB7, member RAS oncogene family	49	0.95
chr12_33343907_33344327	0.41	Atxn7l1	ataxin 7-like 1	1188	0.48
chr11_63921851_63922025	0.41	Hs3st3b1	heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1	352	0.9
chr10_82699022_82699186	0.41	Hcfc2	host cell factor C2	97	0.96
chr17_3314258_3314417	0.41	Gm6475	predicted gene 6475	152	0.95
chr11_46579639_46579790	0.41	BC053393	cDNA sequence BC053393	8178	0.13
chr9_79718618_79718782	0.40	Col12a1	collagen, type XII, alpha 1	20	0.98
chr6_42351028_42351179	0.40	Gm44284	predicted gene, 44284	241	0.79
chr19_5098511_5098662	0.40	Cnih2	cornichon family AMPA receptor auxiliary protein 2	65	0.92
chr3_103102764_103103064	0.39	Dennd2c	DENN/MADD domain containing 2C	254	0.87
chrX_170009083_170009242	0.39	Erdr1	erythroid differentiation regulator 1	497	0.77
chr1_69106969_69107132	0.38	Gm16076	predicted gene 16076	310	0.75
chr4_116150546_116150980	0.38	Pomgnt1	protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase	238	0.72
chr7_139011119_139011285	0.38	Gm45613	predicted gene 45613	9797	0.17
chr12_40446615_40446783	0.38	Dock4	dedicator of cytokinesis 4	363	0.74
chr15_68928178_68928454	0.38	Khdrbs3	KH domain containing, RNA binding, signal transduction associated 3	104	0.97
chrX_13461389_13461908	0.38	Nyx	nyctalopin	4462	0.22
chr13_95375033_95375198	0.38	Aggf1	angiogenic factor with G patch and FHA domains 1	219	0.92
chr15_102355539_102355690	0.37	Gm36246	predicted gene, 36246	4787	0.09
chr6_117907668_117908056	0.37	4933440N22Rik	RIKEN cDNA 4933440N22 gene	102	0.91
chr8_71463353_71463512	0.37	Abhd8	abhydrolase domain containing 8	190	0.85
chr12_83951067_83951218	0.37	Gm26571	predicted gene, 26571	213	0.74
chr15_76948820_76949087	0.37	1110038F14Rik	RIKEN cDNA 1110038F14 gene	204	0.89
chr5_104508532_104508697	0.37	Thoc2l	THO complex subunit 2-like	262	0.91
chr7_127277970_127278299	0.36	Sephs2	selenophosphate synthetase 2	4079	0.08
chr8_88362172_88362513	0.36	Brd7	bromodomain containing 7	148	0.96
chr4_19569576_19569745	0.36	Cpne3	copine III	423	0.84
chr9_110333595_110333757	0.36	Scap	SREBF chaperone	40	0.96
chr2_36091235_36091637	0.36	Lhx6	LIM homeobox protein 6	2837	0.18
chr3_40800182_40800381	0.35	Plk4	polo like kinase 4	27	0.96
chr2_162931309_162931591	0.35	Srsf6	serine and arginine-rich splicing factor 6	78	0.96
chr4_129672269_129672601	0.35	Kpna6	karyopherin (importin) alpha 6	93	0.94
chr4_3939020_3939731	0.35	Chchd7	coiled-coil-helix-coiled-coil-helix domain containing 7	47	0.94
chr9_59617318_59618012	0.35	Parp6	poly (ADP-ribose) polymerase family, member 6	285	0.88
chr1_86359812_86360105	0.35	C130036L24Rik	RIKEN cDNA C130036L24 gene	370	0.52
chr5_52190254_52190520	0.35	Dhx15	DEAH (Asp-Glu-Ala-His) box polypeptide 15	10	0.8
chr4_45972581_45972977	0.35	Tdrd7	tudor domain containing 7	55	0.98
chr19_46056737_46057343	0.35	Pprc1	peroxisome proliferative activated receptor, gamma, coactivator-related 1	176	0.92
chr11_119938815_119938982	0.35	Gm11766	predicted gene 11766	387	0.76
chr2_32587154_32587305	0.35	St6galnac4	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4	90	0.92
chr8_46509584_46509735	0.34	Acsl1	acyl-CoA synthetase long-chain family member 1	16827	0.14
chr19_44554722_44555277	0.34	Ndufb8	NADH:ubiquinone oxidoreductase subunit B8	13	0.96
chr8_126474497_126474692	0.34	Tarbp1	TAR RNA binding protein 1	471	0.78
chr2_70509001_70509542	0.34	Erich2os	glutamate rich 2, opposite strand	72	0.66
chr16_21787535_21788055	0.34	Ehhadh	enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase	12	0.96
chr5_33629299_33629457	0.34	Fam53a	family with sequence similarity 53, member A	205	0.76
chr10_40141741_40141897	0.34	Slc16a10	solute carrier family 16 (monocarboxylic acid transporters), member 10	435	0.77
chr4_134511213_134511411	0.34	Aunip	aurora kinase A and ninein interacting protein	313	0.81
chr5_96161071_96161222	0.34	Cnot6l	CCR4-NOT transcription complex, subunit 6-like	401	0.86
chr17_34647327_34647478	0.34	Atf6b	activating transcription factor 6 beta	191	0.81
chr1_179517745_179517898	0.33	Smyd3	SET and MYND domain containing 3	184	0.93
chr8_107436262_107436429	0.33	Wwp2	WW domain containing E3 ubiquitin protein ligase 2	20	0.96
chr4_83486147_83486301	0.33	Psip1	PC4 and SFRS1 interacting protein 1	46	0.96
chr13_117602276_117602441	0.33	Hcn1	hyperpolarization activated cyclic nucleotide gated potassium channel 1	38	0.99
chr14_78536823_78537132	0.33	Akap11	A kinase (PRKA) anchor protein 11	169	0.96
chr6_137497622_137497773	0.33	Eps8	epidermal growth factor receptor pathway substrate 8	22006	0.2
chr5_107986733_107986901	0.33	Dipk1a	divergent protein kinase domain 1A	216	0.91
chr15_98805374_98805536	0.33	B130046B21Rik	RIKEN cDNA B130046B21 gene	1569	0.19
chr4_84884750_84884930	0.33	Cntln	centlein, centrosomal protein	375	0.89
chr4_43875401_43875556	0.33	Reck	reversion-inducing-cysteine-rich protein with kazal motifs	52	0.96
chr11_97415707_97415862	0.33	Arhgap23	Rho GTPase activating protein 23	251	0.91
chr13_34724917_34725536	0.32	Gm47151	predicted gene, 47151	4475	0.13
chr7_31053117_31053317	0.32	Fxyd1	FXYD domain-containing ion transport regulator 1	95	0.91
chr6_116337865_116338039	0.32	Gm44957	predicted gene 44957	3	0.54
chr4_133038484_133038643	0.32	Ahdc1	AT hook, DNA binding motif, containing 1	930	0.58
chr5_96374293_96374750	0.32	Fras1	Fraser extracellular matrix complex subunit 1	86	0.98
chr6_48047541_48047712	0.32	Zfp777	zinc finger protein 777	168	0.88
chr11_100355800_100355973	0.32	Hap1	huntingtin-associated protein 1	201	0.85
chr8_92355755_92356018	0.32	Crnde	colorectal neoplasia differentially expressed (non-protein coding)	5	0.97
chr7_89338213_89338585	0.31	Gm44995	predicted gene 44995	29	0.8
chr5_53998780_53998931	0.31	Stim2	stromal interaction molecule 2	290	0.93
chr1_36361376_36361537	0.31	Kansl3	KAT8 regulatory NSL complex subunit 3	6558	0.13
chr3_96527165_96527465	0.31	Hjv	hemojuvelin BMP co-receptor	2143	0.13
chr11_103360146_103360491	0.31	Arhgap27	Rho GTPase activating protein 27	582	0.61
chr11_79788800_79788961	0.31	9130204K15Rik	RIKEN cDNA 9130204K15 gene	5993	0.19
chr7_25704801_25704957	0.31	Ccdc97	coiled-coil domain containing 97	11227	0.09
chr5_36544235_36544394	0.31	Tbc1d14	TBC1 domain family, member 14	12712	0.16
chr2_162932009_162932180	0.31	Srsf6	serine and arginine-rich splicing factor 6	433	0.75
chr17_27203974_27204125	0.31	Lemd2	LEM domain containing 2	373	0.74
chr2_28840041_28840192	0.30	Gtf3c4	general transcription factor IIIC, polypeptide 4	170	0.65
chr17_28247644_28247932	0.30	Ppard	peroxisome proliferator activator receptor delta	14981	0.1
chr12_113140083_113140277	0.30	Crip2	cysteine rich protein 2	56	0.95
chr17_32036104_32036455	0.30	Hsf2bp	heat shock transcription factor 2 binding protein	70	0.55
chr16_5049903_5050066	0.30	Ubn1	ubinuclein 1	73	0.56
chr5_122284523_122284674	0.30	Pptc7	PTC7 protein phosphatase homolog	233	0.88
chr7_81829102_81829287	0.30	Btbd1	BTB (POZ) domain containing 1	139	0.92
chr7_35802685_35802845	0.30	E130304I02Rik	RIKEN cDNA E130304I02 gene	172	0.52
chr3_31094797_31095132	0.30	Skil	SKI-like	94	0.97
chr19_6061300_6061504	0.30	Znhit2	zinc finger, HIT domain containing 2	210	0.75
chr7_13006960_13007136	0.30	Zbtb45	zinc finger and BTB domain containing 45	2752	0.11
chr8_89006791_89006942	0.30	Mir8110	microRNA 8110	17869	0.22
chrX_48314618_48314898	0.30	Gm22612	predicted gene, 22612	7715	0.14
chr5_120503570_120503729	0.30	Plbd2	phospholipase B domain containing 2	24	0.96
chr17_34836259_34836412	0.30	Stk19	serine/threonine kinase 19	130	0.8
chr4_44990424_44990616	0.30	Grhpr	glyoxylate reductase/hydroxypyruvate reductase	9020	0.11
chr6_145746379_145746566	0.29	Gm15704	predicted gene 15704	199	0.6
chr3_52267780_52268128	0.29	Foxo1	forkhead box O1	382	0.75
chr4_59805154_59805454	0.29	Snx30	sorting nexin family member 30	536	0.74
chr12_59219022_59219224	0.29	Fbxo33	F-box protein 33	322	0.86
chr3_83997693_83997871	0.29	Tmem131l	transmembrane 131 like	29554	0.2
chr5_129501876_129502027	0.29	Sfswap	splicing factor SWAP	443	0.69
chr15_36938534_36938914	0.29	Gm34590	predicted gene, 34590	140	0.95
chr10_77052221_77052622	0.29	Col18a1	collagen, type XVIII, alpha 1	7576	0.14
chr15_73184065_73184457	0.29	Ago2	argonaute RISC catalytic subunit 2	674	0.71
chr12_70102468_70102860	0.29	Nin	ninein	190	0.93
chr7_39588769_39589060	0.28	Gm2058	predicted gene 2058	17	0.97
chr13_95616710_95616861	0.28	F2r	coagulation factor II (thrombin) receptor	1702	0.32
chr8_25840480_25840643	0.28	Ash2l	ASH2 like histone lysine methyltransferase complex subunit	104	0.95
chr5_137032801_137032974	0.28	Vgf	VGF nerve growth factor inducible	2186	0.16
chr9_118925387_118925554	0.28	Gm16295	predicted gene 16295	597	0.43
chr16_10835322_10835499	0.28	Rmi2	RecQ mediated genome instability 2	342	0.77
chr15_81810928_81811093	0.28	Tef	thyrotroph embryonic factor	36	0.95
chr14_30825749_30825900	0.28	Stimate	STIM activating enhancer	230	0.9
chr1_132138412_132138569	0.28	Gm29629	predicted gene 29629	1014	0.32
chr2_34406921_34407072	0.28	Mapkap1	mitogen-activated protein kinase associated protein 1	110	0.96
chr11_72796331_72796482	0.28	Zzef1	zinc finger, ZZ-type with EF hand domain 1	152	0.65
chr2_160731435_160731699	0.27	Plcg1	phospholipase C, gamma 1	132	0.96
chr10_121586732_121586893	0.27	Tbk1	TANK-binding kinase 1	25	0.97
chr5_24424830_24425266	0.27	Slc4a2	solute carrier family 4 (anion exchanger), member 2	184	0.83
chr3_145576331_145576668	0.27	Znhit6	zinc finger, HIT type 6	163	0.96
chr1_74661925_74662355	0.27	Ttll4	tubulin tyrosine ligase-like family, member 4	323	0.84
chr12_111165833_111166231	0.27	Traf3	TNF receptor-associated factor 3	338	0.87
chr15_73512630_73512863	0.27	Dennd3	DENN/MADD domain containing 3	74	0.97
chr2_31974197_31974505	0.27	Nup214	nucleoporin 214	85	0.95
chr5_74068070_74068221	0.27	Usp46	ubiquitin specific peptidase 46	275	0.84
chr16_8566280_8566445	0.27	Abat	4-aminobutyrate aminotransferase	6540	0.17
chr19_46628011_46628401	0.27	Wbp1l	WW domain binding protein 1 like	4805	0.15
chr10_25360528_25360679	0.27	Epb41l2	erythrocyte membrane protein band 4.1 like 2	747	0.67
chr12_5375671_5375936	0.27	2810032G03Rik	RIKEN cDNA 2810032G03 gene	67	0.57
chr3_95855730_95856038	0.27	Prpf3	pre-mRNA processing factor 3	1	0.55
chr5_122502572_122502773	0.27	Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2	447	0.67
chr11_77077912_77078299	0.26	Mir423	microRNA 423	67	0.49
chr9_56995068_56995592	0.26	Ptpn9	protein tyrosine phosphatase, non-receptor type 9	234	0.9
chr7_102441286_102441479	0.26	Rrm1	ribonucleotide reductase M1	313	0.8
chr10_88503866_88504026	0.26	Chpt1	choline phosphotransferase 1	21	0.97

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2d

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	0.9	GO:0045218	zonula adherens maintenance(GO:0045218)
0.2	0.7	GO:1902953	positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.2	0.6	GO:1902513	regulation of organelle transport along microtubule(GO:1902513)
0.2	0.5	GO:0006663	platelet activating factor biosynthetic process(GO:0006663) platelet activating factor metabolic process(GO:0046469)
0.2	0.5	GO:0046077	dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2	0.5	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.1	0.1	GO:0036118	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1	0.4	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.1	0.4	GO:1900740	regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1	0.4	GO:2000383	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1	0.5	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.1	0.4	GO:1905049	negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.1	0.4	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1	1.0	GO:0032875	regulation of DNA endoreduplication(GO:0032875)
0.1	0.5	GO:0003383	apical constriction(GO:0003383)
0.1	0.7	GO:0015871	choline transport(GO:0015871)
0.1	0.6	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.1	0.6	GO:0000395	mRNA 5'-splice site recognition(GO:0000395)
0.1	0.3	GO:0018242	protein O-linked glycosylation via serine(GO:0018242)
0.1	0.3	GO:1903599	positive regulation of mitophagy(GO:1903599)
0.1	0.3	GO:1902630	regulation of membrane hyperpolarization(GO:1902630)
0.1	0.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.1	0.6	GO:0048069	eye pigmentation(GO:0048069)
0.1	0.4	GO:0061724	lipophagy(GO:0061724)
0.1	0.3	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.1	0.1	GO:0018243	protein O-linked glycosylation via threonine(GO:0018243)
0.1	0.3	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1	0.4	GO:0071139	resolution of recombination intermediates(GO:0071139)
0.1	0.3	GO:0098535	de novo centriole assembly(GO:0098535)
0.1	0.5	GO:0006477	protein sulfation(GO:0006477)
0.1	0.6	GO:2000675	negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1	0.2	GO:0043988	histone H3-S28 phosphorylation(GO:0043988)
0.1	0.3	GO:1903797	positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1	0.3	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1	0.5	GO:0035092	sperm chromatin condensation(GO:0035092)
0.1	0.4	GO:0042769	DNA damage response, detection of DNA damage(GO:0042769)
0.1	0.1	GO:1901420	negative regulation of response to alcohol(GO:1901420)
0.1	0.1	GO:0036506	maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.1	0.5	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1	0.4	GO:0010457	centriole-centriole cohesion(GO:0010457)
0.1	0.3	GO:0051697	protein delipidation(GO:0051697)
0.1	0.3	GO:0010887	negative regulation of cholesterol storage(GO:0010887)
0.1	0.4	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	0.2	GO:0010166	wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.1	0.1	GO:1902661	regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
0.1	0.2	GO:0030951	establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1	0.1	GO:1902174	positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1	0.3	GO:0048254	snoRNA localization(GO:0048254)
0.1	0.2	GO:1904139	microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1	0.2	GO:1904469	positive regulation of tumor necrosis factor secretion(GO:1904469)
0.1	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.1	0.1	GO:0042706	eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1	0.2	GO:0090230	regulation of centromere complex assembly(GO:0090230)
0.1	0.2	GO:0021586	pons maturation(GO:0021586)
0.1	0.8	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.1	0.2	GO:0045039	protein import into mitochondrial inner membrane(GO:0045039)
0.1	0.4	GO:1902231	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.1	0.3	GO:0032237	activation of store-operated calcium channel activity(GO:0032237)
0.1	0.2	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.1	0.1	GO:0035973	aggrephagy(GO:0035973)
0.1	0.2	GO:0031508	pericentric heterochromatin assembly(GO:0031508)
0.1	0.4	GO:0071501	response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.1	0.2	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.1	2.1	GO:0042771	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1	0.4	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.1	0.2	GO:0034773	histone H4-K20 trimethylation(GO:0034773)
0.1	0.2	GO:1904059	regulation of locomotor rhythm(GO:1904059)
0.1	0.2	GO:0061113	pancreas morphogenesis(GO:0061113)
0.1	0.2	GO:0061043	regulation of vascular wound healing(GO:0061043)
0.1	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1	0.6	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	0.1	GO:0071725	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1	0.2	GO:0035087	siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1	0.2	GO:0070126	mitochondrial translational termination(GO:0070126)
0.1	0.4	GO:0021540	corpus callosum morphogenesis(GO:0021540)
0.0	0.5	GO:0006517	protein deglycosylation(GO:0006517)
0.0	0.2	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.1	GO:0061623	galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0	0.1	GO:0017187	peptidyl-glutamic acid carboxylation(GO:0017187)
0.0	0.6	GO:0046855	inositol phosphate dephosphorylation(GO:0046855)
0.0	0.1	GO:0045726	positive regulation of integrin biosynthetic process(GO:0045726)
0.0	0.1	GO:0009826	unidimensional cell growth(GO:0009826)
0.0	0.5	GO:0045899	positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0	0.4	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.2	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.2	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.1	GO:0030208	dermatan sulfate biosynthetic process(GO:0030208)
0.0	0.1	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.0	0.6	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.1	GO:0071492	cellular response to UV-A(GO:0071492)
0.0	0.2	GO:0033762	response to glucagon(GO:0033762)
0.0	0.1	GO:0033159	negative regulation of protein import into nucleus, translocation(GO:0033159)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.2	GO:0035519	protein K29-linked ubiquitination(GO:0035519)
0.0	0.1	GO:1902990	mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0	0.1	GO:0036023	limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0	0.0	GO:1900368	regulation of RNA interference(GO:1900368)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.1	GO:0044339	canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0	0.2	GO:0006041	glucosamine metabolic process(GO:0006041)
0.0	0.0	GO:0036258	multivesicular body assembly(GO:0036258)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0070973	protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0	0.1	GO:1904238	pericyte cell differentiation(GO:1904238)
0.0	0.2	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.6	GO:0032331	negative regulation of chondrocyte differentiation(GO:0032331)
0.0	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.1	GO:0032066	nucleolus to nucleoplasm transport(GO:0032066)
0.0	0.2	GO:0008616	queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0	0.3	GO:1904417	regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.0	0.1	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.2	GO:2000189	positive regulation of cholesterol homeostasis(GO:2000189)
0.0	0.1	GO:0001922	B-1 B cell homeostasis(GO:0001922)
0.0	0.2	GO:0007262	STAT protein import into nucleus(GO:0007262)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.1	GO:1903911	positive regulation of receptor clustering(GO:1903911) regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0	0.1	GO:0015819	lysine transport(GO:0015819)
0.0	0.1	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0070294	renal sodium ion absorption(GO:0070294)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.1	GO:0038086	VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0	0.2	GO:2000323	negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0	0.1	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.3	GO:0048149	behavioral response to ethanol(GO:0048149)
0.0	0.2	GO:0044331	cell-cell adhesion mediated by cadherin(GO:0044331)
0.0	0.1	GO:0090086	negative regulation of protein deubiquitination(GO:0090086)
0.0	0.0	GO:0002309	T cell proliferation involved in immune response(GO:0002309)
0.0	0.5	GO:0006855	drug transmembrane transport(GO:0006855)
0.0	0.2	GO:1902993	positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0	0.2	GO:0042078	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.5	GO:0006828	manganese ion transport(GO:0006828)
0.0	0.1	GO:0035630	bone mineralization involved in bone maturation(GO:0035630)
0.0	0.1	GO:0045079	negative regulation of chemokine biosynthetic process(GO:0045079)
0.0	0.2	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.2	GO:0017196	N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0	0.3	GO:0045607	regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.3	GO:0048096	chromatin-mediated maintenance of transcription(GO:0048096)
0.0	0.1	GO:0000389	mRNA 3'-splice site recognition(GO:0000389)
0.0	0.0	GO:2000017	positive regulation of determination of dorsal identity(GO:2000017)
0.0	0.2	GO:0071051	polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.2	GO:0008063	Toll signaling pathway(GO:0008063)
0.0	0.6	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.3	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0070827	chromatin maintenance(GO:0070827)
0.0	0.1	GO:0034727	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.1	GO:0071681	response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0	0.1	GO:0035359	negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.0	0.1	GO:2000646	positive regulation of receptor catabolic process(GO:2000646)
0.0	0.1	GO:0010668	ectodermal cell differentiation(GO:0010668)
0.0	0.1	GO:0071877	regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0	0.3	GO:1990440	positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0	0.1	GO:0098532	histone H3-K27 trimethylation(GO:0098532)
0.0	0.1	GO:0007199	G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0	0.1	GO:2001199	negative regulation of dendritic cell differentiation(GO:2001199)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.1	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:2000394	positive regulation of lamellipodium morphogenesis(GO:2000394)
0.0	0.1	GO:0003257	positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257)
0.0	0.1	GO:0035523	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.2	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.0	GO:1902947	regulation of tau-protein kinase activity(GO:1902947)
0.0	0.1	GO:0035280	miRNA loading onto RISC involved in gene silencing by miRNA(GO:0035280)
0.0	0.0	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.4	GO:0043457	regulation of cellular respiration(GO:0043457)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.1	GO:1904742	regulation of telomeric DNA binding(GO:1904742)
0.0	0.4	GO:0060009	Sertoli cell development(GO:0060009)
0.0	0.2	GO:0032988	ribonucleoprotein complex disassembly(GO:0032988)
0.0	0.1	GO:1903553	positive regulation of extracellular exosome assembly(GO:1903553)
0.0	0.1	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.3	GO:1901663	ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0	0.1	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
0.0	0.2	GO:2000348	regulation of CD40 signaling pathway(GO:2000348)
0.0	0.0	GO:2000847	negative regulation of steroid hormone secretion(GO:2000832) negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.4	GO:0010971	positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0	0.1	GO:0006384	transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0	0.1	GO:0016259	selenocysteine metabolic process(GO:0016259)
0.0	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0010587	miRNA catabolic process(GO:0010587)
0.0	0.1	GO:0044704	single-organism reproductive behavior(GO:0044704)
0.0	0.0	GO:0060336	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.0	GO:1902263	apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.0	0.1	GO:2001274	negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:0060743	epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0	0.0	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.0	GO:0008588	release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0	0.3	GO:0003338	metanephros morphogenesis(GO:0003338)
0.0	0.1	GO:2000059	negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000059)
0.0	0.3	GO:0071549	cellular response to dexamethasone stimulus(GO:0071549)
0.0	0.2	GO:0097033	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0	0.2	GO:0009263	deoxyribonucleotide biosynthetic process(GO:0009263)
0.0	0.0	GO:1904179	regulation of adipose tissue development(GO:1904177) positive regulation of adipose tissue development(GO:1904179)
0.0	0.0	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.4	GO:0001574	ganglioside biosynthetic process(GO:0001574)
0.0	0.1	GO:0016266	O-glycan processing(GO:0016266)
0.0	0.0	GO:0006501	C-terminal protein lipidation(GO:0006501)
0.0	0.1	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.1	GO:0006978	DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) DNA damage response, signal transduction resulting in transcription(GO:0042772)
0.0	0.1	GO:0099515	actin filament-based transport(GO:0099515)
0.0	0.0	GO:0045869	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0	0.0	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:0042780	tRNA 3'-end processing(GO:0042780)
0.0	0.1	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0032532	regulation of microvillus length(GO:0032532)
0.0	0.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.2	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0	0.1	GO:0009130	UMP biosynthetic process(GO:0006222) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.2	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.1	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.1	GO:0060800	regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0	0.1	GO:0044791	modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0060056	mammary gland involution(GO:0060056)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.1	GO:0042760	very long-chain fatty acid catabolic process(GO:0042760)
0.0	0.1	GO:0019676	ammonia assimilation cycle(GO:0019676)
0.0	0.1	GO:1903887	motile primary cilium assembly(GO:1903887)
0.0	0.0	GO:1903525	regulation of membrane tubulation(GO:1903525)
0.0	0.1	GO:1902775	mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0044375	regulation of peroxisome size(GO:0044375)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.1	GO:0045896	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.0	0.0	GO:0018076	N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0	0.1	GO:0044598	polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0019673	GDP-mannose metabolic process(GO:0019673)
0.0	0.3	GO:0070306	lens fiber cell differentiation(GO:0070306)
0.0	0.4	GO:0048384	retinoic acid receptor signaling pathway(GO:0048384)
0.0	0.5	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.0	GO:0038109	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0090344	negative regulation of cell aging(GO:0090344)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0031034	myosin filament assembly(GO:0031034)
0.0	0.1	GO:0009158	ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0	0.1	GO:0001805	type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.1	GO:0001514	selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0	0.7	GO:0010501	RNA secondary structure unwinding(GO:0010501)
0.0	0.0	GO:0071376	response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.0	0.1	GO:0015879	carnitine transport(GO:0015879)
0.0	0.0	GO:1902255	positive regulation of intrinsic apoptotic signaling pathway by p53 class mediator(GO:1902255)
0.0	0.6	GO:0008333	endosome to lysosome transport(GO:0008333)
0.0	0.1	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0	0.1	GO:0050917	sensory perception of umami taste(GO:0050917)
0.0	0.1	GO:0008635	activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0	0.3	GO:0006706	steroid catabolic process(GO:0006706)
0.0	0.1	GO:0060766	negative regulation of androgen receptor signaling pathway(GO:0060766)
0.0	0.0	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0	0.0	GO:0070245	positive regulation of thymocyte apoptotic process(GO:0070245)
0.0	0.0	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.7	GO:0006611	protein export from nucleus(GO:0006611)
0.0	0.0	GO:0071476	cellular hypotonic response(GO:0071476)
0.0	0.1	GO:0007008	outer mitochondrial membrane organization(GO:0007008)
0.0	0.0	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.0	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.2	GO:0035066	positive regulation of histone acetylation(GO:0035066)
0.0	0.2	GO:0007210	serotonin receptor signaling pathway(GO:0007210)
0.0	0.1	GO:0090306	spindle assembly involved in meiosis(GO:0090306)
0.0	0.1	GO:0033133	positive regulation of glucokinase activity(GO:0033133)
0.0	0.0	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.0	GO:0048102	autophagic cell death(GO:0048102)
0.0	0.0	GO:0010835	regulation of protein ADP-ribosylation(GO:0010835)
0.0	0.2	GO:0043984	histone H4-K16 acetylation(GO:0043984)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0021670	lateral ventricle development(GO:0021670)
0.0	0.1	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.1	GO:0060340	positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0	0.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.0	GO:0021797	forebrain anterior/posterior pattern specification(GO:0021797)
0.0	0.1	GO:0000022	mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0	0.1	GO:1902626	assembly of large subunit precursor of preribosome(GO:1902626)
0.0	0.1	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.1	GO:0060770	negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0	0.0	GO:0072602	interleukin-4 secretion(GO:0072602)
0.0	0.0	GO:0030382	sperm mitochondrion organization(GO:0030382)
0.0	0.0	GO:0042723	thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.0	0.1	GO:0051988	regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0	0.1	GO:0071494	cellular response to UV-C(GO:0071494)
0.0	0.0	GO:0036135	Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0	0.0	GO:0044154	histone H3-K14 acetylation(GO:0044154)
0.0	0.2	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.3	GO:0046677	response to antibiotic(GO:0046677)
0.0	0.1	GO:0060914	heart formation(GO:0060914)
0.0	0.0	GO:1900045	negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915)
0.0	0.1	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.1	GO:0036336	dendritic cell migration(GO:0036336)
0.0	0.0	GO:0071926	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.1	GO:0070572	positive regulation of axon regeneration(GO:0048680) positive regulation of neuron projection regeneration(GO:0070572)
0.0	0.1	GO:0018231	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.1	GO:0051458	corticotropin secretion(GO:0051458) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.0	0.1	GO:0001778	plasma membrane repair(GO:0001778)
0.0	0.1	GO:0043568	positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0	0.0	GO:0018206	peptidyl-methionine modification(GO:0018206)
0.0	0.1	GO:0035735	intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0	0.1	GO:0000185	activation of MAPKKK activity(GO:0000185)
0.0	0.2	GO:0001522	pseudouridine synthesis(GO:0001522)
0.0	0.0	GO:0034139	regulation of toll-like receptor 3 signaling pathway(GO:0034139) positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.0	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.0	0.1	GO:0090209	negative regulation of triglyceride metabolic process(GO:0090209)
0.0	0.0	GO:0045415	negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0	0.2	GO:0021527	spinal cord association neuron differentiation(GO:0021527)
0.0	0.0	GO:0023041	neuronal signal transduction(GO:0023041)
0.0	0.0	GO:0090325	regulation of locomotion involved in locomotory behavior(GO:0090325)
0.0	0.1	GO:0032099	negative regulation of appetite(GO:0032099)
0.0	0.0	GO:0006177	GMP biosynthetic process(GO:0006177)
0.0	0.0	GO:0002254	kinin cascade(GO:0002254)
0.0	0.1	GO:1904936	cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0	0.1	GO:0070327	thyroid hormone transport(GO:0070327)
0.0	0.0	GO:2000566	positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0	0.0	GO:0032439	endosome localization(GO:0032439)
0.0	0.0	GO:0000055	ribosomal large subunit export from nucleus(GO:0000055)
0.0	0.1	GO:0034063	stress granule assembly(GO:0034063)
0.0	0.2	GO:0050995	negative regulation of lipid catabolic process(GO:0050995)
0.0	0.0	GO:0035414	negative regulation of catenin import into nucleus(GO:0035414)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:0021747	cochlear nucleus development(GO:0021747)
0.0	0.2	GO:0044342	type B pancreatic cell proliferation(GO:0044342)
0.0	0.0	GO:0043097	pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0	0.0	GO:0032252	secretory granule localization(GO:0032252)
0.0	0.1	GO:0042036	negative regulation of cytokine biosynthetic process(GO:0042036)
0.0	0.2	GO:0033273	response to vitamin(GO:0033273)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.0	GO:0033088	negative regulation of immature T cell proliferation in thymus(GO:0033088)
0.0	0.0	GO:0030210	heparin biosynthetic process(GO:0030210)
0.0	0.0	GO:0048807	female genitalia morphogenesis(GO:0048807)
0.0	0.0	GO:0090666	scaRNA localization to Cajal body(GO:0090666)
0.0	0.1	GO:0003203	endocardial cushion morphogenesis(GO:0003203)
0.0	0.1	GO:0000920	cell separation after cytokinesis(GO:0000920)
0.0	0.0	GO:0001705	ectoderm formation(GO:0001705)
0.0	0.0	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0002634	regulation of germinal center formation(GO:0002634)
0.0	0.0	GO:0051562	negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0	0.0	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0	0.1	GO:2000051	negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0	0.1	GO:0034501	protein localization to kinetochore(GO:0034501)
0.0	0.1	GO:0043508	negative regulation of JUN kinase activity(GO:0043508)
0.0	0.1	GO:0060390	regulation of SMAD protein import into nucleus(GO:0060390)
0.0	0.0	GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043516)
0.0	0.0	GO:0097461	ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
0.0	0.6	GO:0043484	regulation of RNA splicing(GO:0043484)
0.0	0.1	GO:1902547	regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902547)
0.0	0.0	GO:0010804	negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0035845	photoreceptor cell outer segment organization(GO:0035845)
0.0	0.1	GO:0036089	cleavage furrow formation(GO:0036089)
0.0	0.0	GO:1900060	negative regulation of sphingolipid biosynthetic process(GO:0090155) cellular sphingolipid homeostasis(GO:0090156) negative regulation of ceramide biosynthetic process(GO:1900060)
0.0	0.1	GO:0045724	positive regulation of cilium assembly(GO:0045724)
0.0	0.3	GO:1901016	regulation of potassium ion transmembrane transporter activity(GO:1901016)
0.0	0.0	GO:0021529	spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.0	0.0	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0060338	regulation of type I interferon-mediated signaling pathway(GO:0060338)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.9	GO:0005915	zonula adherens(GO:0005915)
0.1	0.5	GO:0033269	internode region of axon(GO:0033269)
0.1	0.4	GO:0035061	interchromatin granule(GO:0035061)
0.1	0.4	GO:0005593	FACIT collagen trimer(GO:0005593)
0.1	0.3	GO:0016222	procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1	0.3	GO:0036449	microtubule minus-end(GO:0036449)
0.1	0.3	GO:0098536	deuterosome(GO:0098536)
0.1	0.3	GO:0097136	Bcl-2 family protein complex(GO:0097136)
0.1	0.2	GO:0005971	ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1	0.1	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.1	0.2	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1	0.5	GO:0000306	extrinsic component of vacuolar membrane(GO:0000306)
0.1	0.2	GO:0090498	extrinsic component of Golgi membrane(GO:0090498)
0.1	0.2	GO:0071008	U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1	0.2	GO:0005726	perichromatin fibrils(GO:0005726)
0.1	0.5	GO:0008278	cohesin complex(GO:0008278)
0.1	0.3	GO:0001739	sex chromatin(GO:0001739)
0.1	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0072379	BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0	0.2	GO:0005672	transcription factor TFIIA complex(GO:0005672)
0.0	0.1	GO:0042719	mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0	0.3	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0097427	microtubule bundle(GO:0097427)
0.0	0.4	GO:0035253	ciliary rootlet(GO:0035253)
0.0	0.2	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.3	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.5	GO:0000421	autophagosome membrane(GO:0000421)
0.0	0.1	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0043527	tRNA methyltransferase complex(GO:0043527)
0.0	0.3	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.2	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.5	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0070776	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.1	GO:0030478	actin cap(GO:0030478)
0.0	0.1	GO:1990423	RZZ complex(GO:1990423)
0.0	0.2	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:1990316	ATG1/ULK1 kinase complex(GO:1990316)
0.0	0.1	GO:0030689	Noc complex(GO:0030689)
0.0	0.1	GO:0016939	kinesin II complex(GO:0016939)
0.0	1.1	GO:0005776	autophagosome(GO:0005776)
0.0	0.2	GO:0034715	pICln-Sm protein complex(GO:0034715)
0.0	0.4	GO:0033391	chromatoid body(GO:0033391)
0.0	0.5	GO:0031082	BLOC complex(GO:0031082)
0.0	0.1	GO:0000322	storage vacuole(GO:0000322)
0.0	0.5	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0072487	MSL complex(GO:0072487)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.0	0.3	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.0	0.3	GO:0005652	nuclear lamina(GO:0005652)
0.0	0.3	GO:0035631	CD40 receptor complex(GO:0035631)
0.0	0.1	GO:0030289	protein phosphatase 4 complex(GO:0030289)
0.0	1.6	GO:0005643	nuclear pore(GO:0005643)
0.0	0.3	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0031258	lamellipodium membrane(GO:0031258)
0.0	0.4	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.2	GO:0000801	central element(GO:0000801)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.0	GO:0034274	Atg12-Atg5-Atg16 complex(GO:0034274)
0.0	0.2	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0043293	apoptosome(GO:0043293)
0.0	0.0	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.3	GO:0071011	precatalytic spliceosome(GO:0071011)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0097418	neurofibrillary tangle(GO:0097418)
0.0	0.2	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	0.3	GO:0031229	integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0	0.1	GO:0000243	commitment complex(GO:0000243)
0.0	0.0	GO:0070765	gamma-secretase complex(GO:0070765)
0.0	0.3	GO:0005686	U2 snRNP(GO:0005686)
0.0	0.1	GO:0031415	NatA complex(GO:0031415)
0.0	0.3	GO:0043218	compact myelin(GO:0043218)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0000930	gamma-tubulin complex(GO:0000930)
0.0	0.1	GO:0030896	checkpoint clamp complex(GO:0030896)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0042575	DNA polymerase complex(GO:0042575)
0.0	0.1	GO:0090576	RNA polymerase III transcription factor complex(GO:0090576)
0.0	0.1	GO:0036156	inner dynein arm(GO:0036156)
0.0	0.1	GO:0031094	platelet dense tubular network(GO:0031094)
0.0	0.8	GO:0031903	peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0	0.3	GO:0097440	apical dendrite(GO:0097440)
0.0	0.2	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.2	GO:0030660	Golgi-associated vesicle membrane(GO:0030660)
0.0	0.2	GO:0070852	cell body fiber(GO:0070852)
0.0	0.2	GO:0030061	mitochondrial crista(GO:0030061)
0.0	0.3	GO:0090544	BAF-type complex(GO:0090544)
0.0	0.1	GO:0032389	MutLalpha complex(GO:0032389)
0.0	0.1	GO:1990246	uniplex complex(GO:1990246)
0.0	0.4	GO:0000307	cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0	0.1	GO:0005671	Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0	0.6	GO:0045271	mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0	0.1	GO:0072687	meiotic spindle(GO:0072687)
0.0	0.1	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.1	GO:0032045	guanyl-nucleotide exchange factor complex(GO:0032045)
0.0	0.1	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	1.1	GO:0090575	RNA polymerase II transcription factor complex(GO:0090575)
0.0	0.1	GO:0008385	IkappaB kinase complex(GO:0008385)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.1	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0	0.1	GO:0016442	RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.2	GO:0035145	exon-exon junction complex(GO:0035145)
0.0	0.1	GO:0005640	nuclear outer membrane(GO:0005640)
0.0	0.1	GO:0031595	nuclear proteasome complex(GO:0031595)
0.0	0.0	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.0	0.1	GO:0031528	microvillus membrane(GO:0031528)
0.0	0.0	GO:0043219	lateral loop(GO:0043219)
0.0	0.0	GO:0033655	host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.0	0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	0.1	GO:0000124	SAGA complex(GO:0000124)
0.0	0.1	GO:0046540	U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0	0.0	GO:0044530	supraspliceosomal complex(GO:0044530)
0.0	0.0	GO:0034993	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0031232	extrinsic component of external side of plasma membrane(GO:0031232)
0.0	0.1	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.4	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0	0.1	GO:0031414	N-terminal protein acetyltransferase complex(GO:0031414)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0070139	ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.2	0.5	GO:0009041	uridylate kinase activity(GO:0009041)
0.1	0.4	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1	0.5	GO:0004165	dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1	0.4	GO:0047192	1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1	0.5	GO:0008934	inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1	0.4	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.1	0.4	GO:0008467	[heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1	0.5	GO:0005049	nuclear export signal receptor activity(GO:0005049)
0.1	0.3	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	0.2	GO:0035175	histone kinase activity (H3-S10 specific)(GO:0035175)
0.1	0.2	GO:0042296	ISG15 transferase activity(GO:0042296)
0.1	0.3	GO:0051434	BH3 domain binding(GO:0051434)
0.1	0.9	GO:0035497	cAMP response element binding(GO:0035497)
0.1	0.5	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.1	0.4	GO:0015349	thyroid hormone transmembrane transporter activity(GO:0015349)
0.1	0.3	GO:0004656	procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.3	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1	0.2	GO:0004748	ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1	0.3	GO:0055131	C3HC4-type RING finger domain binding(GO:0055131)
0.1	0.2	GO:0005087	Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1	0.2	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1	0.3	GO:0001665	alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1	0.2	GO:0016149	translation release factor activity, codon specific(GO:0016149)
0.1	0.4	GO:0005384	manganese ion transmembrane transporter activity(GO:0005384)
0.1	0.9	GO:1990939	ATP-dependent microtubule motor activity(GO:1990939)
0.1	0.2	GO:0035939	microsatellite binding(GO:0035939)
0.1	0.3	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.1	0.1	GO:0043533	inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0	1.0	GO:0017025	TBP-class protein binding(GO:0017025)
0.0	0.4	GO:0005167	neurotrophin TRK receptor binding(GO:0005167)
0.0	0.2	GO:0061665	SUMO ligase activity(GO:0061665)
0.0	0.2	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.2	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.3	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.1	GO:0031493	nucleosomal histone binding(GO:0031493)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.2	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.2	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.5	GO:0005172	vascular endothelial growth factor receptor binding(GO:0005172)
0.0	0.1	GO:0030620	U2 snRNA binding(GO:0030620)
0.0	0.2	GO:0032184	SUMO polymer binding(GO:0032184)
0.0	0.4	GO:0043996	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.2	GO:0008479	queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0	0.3	GO:0016929	SUMO-specific protease activity(GO:0016929)
0.0	0.6	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.2	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.1	GO:1990050	phosphatidic acid transporter activity(GO:1990050)
0.0	0.2	GO:0033592	RNA strand annealing activity(GO:0033592)
0.0	1.1	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.2	GO:0017169	CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0	0.2	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.1	GO:0042731	PH domain binding(GO:0042731)
0.0	0.4	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.0	0.0	GO:0003696	satellite DNA binding(GO:0003696)
0.0	0.1	GO:1990188	euchromatin binding(GO:1990188)
0.0	0.1	GO:0015057	thrombin receptor activity(GO:0015057)
0.0	0.5	GO:0070577	lysine-acetylated histone binding(GO:0070577)
0.0	0.1	GO:0030572	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	0.3	GO:0005222	intracellular cAMP activated cation channel activity(GO:0005222)
0.0	0.1	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	0.2	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.2	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.1	GO:0004999	vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0	0.1	GO:0004967	glucagon receptor activity(GO:0004967)
0.0	0.1	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0	0.7	GO:0008137	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.8	GO:0036002	pre-mRNA binding(GO:0036002)
0.0	0.4	GO:0070300	phosphatidic acid binding(GO:0070300)
0.0	0.5	GO:0004653	polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0	0.1	GO:0032405	MutLalpha complex binding(GO:0032405)
0.0	0.3	GO:0031996	thioesterase binding(GO:0031996)
0.0	0.2	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.8	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:0017108	5'-flap endonuclease activity(GO:0017108)
0.0	0.1	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.2	GO:1990446	U1 snRNP binding(GO:1990446)
0.0	1.7	GO:0004843	thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0	0.1	GO:0016018	cyclosporin A binding(GO:0016018)
0.0	0.1	GO:0070679	inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0035368	selenocysteine insertion sequence binding(GO:0035368)
0.0	0.1	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	1.1	GO:0030971	receptor tyrosine kinase binding(GO:0030971)
0.0	0.1	GO:0019871	sodium channel inhibitor activity(GO:0019871)
0.0	0.3	GO:0008191	metalloendopeptidase inhibitor activity(GO:0008191)
0.0	0.1	GO:0008853	exodeoxyribonuclease III activity(GO:0008853)
0.0	0.1	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.8	GO:0005109	frizzled binding(GO:0005109)
0.0	0.1	GO:0003873	6-phosphofructo-2-kinase activity(GO:0003873)
0.0	0.6	GO:0004114	3',5'-cyclic-nucleotide phosphodiesterase activity(GO:0004114)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0015189	arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.0	0.3	GO:0034237	protein kinase A regulatory subunit binding(GO:0034237)
0.0	0.1	GO:0005143	interleukin-12 receptor binding(GO:0005143)
0.0	0.1	GO:0034893	mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.2	GO:0015279	store-operated calcium channel activity(GO:0015279)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0036435	K48-linked polyubiquitin binding(GO:0036435)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.5	GO:0051879	Hsp90 protein binding(GO:0051879)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.3	GO:0008327	methyl-CpG binding(GO:0008327)
0.0	0.1	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.2	GO:0004596	peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0	0.1	GO:0035473	lipase binding(GO:0035473)
0.0	0.2	GO:0001206	transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.0	0.2	GO:0005161	platelet-derived growth factor receptor binding(GO:0005161)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.4	GO:0051537	2 iron, 2 sulfur cluster binding(GO:0051537)
0.0	0.1	GO:0000403	Y-form DNA binding(GO:0000403)
0.0	0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.0	1.0	GO:0019003	GDP binding(GO:0019003)
0.0	0.1	GO:0005173	stem cell factor receptor binding(GO:0005173)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0070052	collagen V binding(GO:0070052)
0.0	0.1	GO:0004565	beta-galactosidase activity(GO:0004565)
0.0	0.2	GO:0070700	BMP receptor binding(GO:0070700)
0.0	0.1	GO:0032454	histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0048531	beta-1,3-galactosyltransferase activity(GO:0048531)
0.0	0.1	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0042284	sphingolipid delta-4 desaturase activity(GO:0042284)
0.0	0.1	GO:0001162	RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0	0.2	GO:0048038	quinone binding(GO:0048038)
0.0	1.0	GO:0004004	ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0	0.1	GO:0005499	vitamin D binding(GO:0005499)
0.0	0.0	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.0	GO:0008597	calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0	1.1	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.5	GO:0052770	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.0	GO:0017153	sodium:dicarboxylate symporter activity(GO:0017153)
0.0	0.0	GO:0005519	cytoskeletal regulatory protein binding(GO:0005519)
0.0	0.2	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.0	0.1	GO:0032036	myosin heavy chain binding(GO:0032036)
0.0	0.0	GO:0035529	NADH pyrophosphatase activity(GO:0035529)
0.0	0.3	GO:0003950	NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0	0.1	GO:0016920	pyroglutamyl-peptidase activity(GO:0016920)
0.0	0.2	GO:0030544	Hsp70 protein binding(GO:0030544)
0.0	0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.0	0.3	GO:0005452	inorganic anion exchanger activity(GO:0005452)
0.0	0.1	GO:1901567	icosanoid binding(GO:0050542) arachidonic acid binding(GO:0050544) fatty acid derivative binding(GO:1901567)
0.0	0.1	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0030550	acetylcholine receptor inhibitor activity(GO:0030550)
0.0	0.2	GO:0070008	serine-type exopeptidase activity(GO:0070008)
0.0	0.4	GO:0080032	prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0	0.1	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.1	GO:0034784	pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0	0.1	GO:0035198	miRNA binding(GO:0035198)
0.0	0.6	GO:0003777	microtubule motor activity(GO:0003777)
0.0	0.0	GO:0102007	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0	0.0	GO:0034714	type III transforming growth factor beta receptor binding(GO:0034714)
0.0	0.1	GO:0000268	peroxisome targeting sequence binding(GO:0000268)
0.0	0.1	GO:0070628	proteasome binding(GO:0070628)
0.0	0.1	GO:0010521	telomerase inhibitor activity(GO:0010521)
0.0	0.0	GO:0046935	1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0	0.1	GO:0051010	microtubule plus-end binding(GO:0051010)
0.0	0.1	GO:0042577	lipid phosphatase activity(GO:0042577)
0.0	0.1	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.2	GO:0099589	G-protein coupled serotonin receptor activity(GO:0004993) serotonin receptor activity(GO:0099589)
0.0	0.1	GO:0097602	cullin family protein binding(GO:0097602)
0.0	0.3	GO:0017080	sodium channel regulator activity(GO:0017080)
0.0	0.1	GO:0051011	microtubule minus-end binding(GO:0051011)
0.0	0.0	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.0	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.0	0.2	GO:0017049	GTP-Rho binding(GO:0017049)
0.0	0.4	GO:0043621	protein self-association(GO:0043621)
0.0	0.1	GO:0016505	cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.0	0.0	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.0	0.3	GO:0004879	RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	PID S1P S1P4 PATHWAY	S1P4 pathway
0.1	0.1	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.0	0.4	SA PROGRAMMED CELL DEATH	Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0	1.2	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.9	PID VEGFR1 PATHWAY	VEGFR1 specific signals
0.0	0.1	PID VEGFR1 2 PATHWAY	Signaling events mediated by VEGFR1 and VEGFR2
0.0	0.7	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	1.1	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.2	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.0	0.1	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	0.1	PID ERBB1 RECEPTOR PROXIMAL PATHWAY	EGF receptor (ErbB1) signaling pathway
0.0	0.5	ST ERK1 ERK2 MAPK PATHWAY	ERK1/ERK2 MAPK Pathway
0.0	0.4	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.0	0.8	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.0	0.1	PID INTEGRIN1 PATHWAY	Beta1 integrin cell surface interactions
0.0	0.3	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.8	PID TGFBR PATHWAY	TGF-beta receptor signaling
0.0	0.5	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.7	PID TAP63 PATHWAY	Validated transcriptional targets of TAp63 isoforms
0.0	0.3	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.0	0.4	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.0	0.2	PID ATM PATHWAY	ATM pathway
0.0	0.7	PID AVB3 INTEGRIN PATHWAY	Integrins in angiogenesis
0.0	0.3	PID ERBB4 PATHWAY	ErbB4 signaling events
0.0	0.4	PID P53 REGULATION PATHWAY	p53 pathway
0.0	0.7	WNT SIGNALING	Genes related to Wnt-mediated signal transduction
0.0	0.2	PID AURORA A PATHWAY	Aurora A signaling
0.0	0.3	PID CASPASE PATHWAY	Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION	Genes involved in 3' -UTR-mediated translational regulation
0.1	0.3	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1	0.1	REACTOME TCR SIGNALING	Genes involved in TCR signaling
0.1	0.7	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.1	0.6	REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS	Genes involved in Bile salt and organic anion SLC transporters
0.1	0.6	REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION	Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0	0.5	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.7	REACTOME SYNTHESIS OF PC	Genes involved in Synthesis of PC
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.4	REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS	Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0	0.9	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	1.1	REACTOME G1 PHASE	Genes involved in G1 Phase
0.0	0.5	REACTOME FANCONI ANEMIA PATHWAY	Genes involved in Fanconi Anemia pathway
0.0	0.3	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.4	REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES	Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0	1.1	REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY	Genes involved in Nuclear Receptor transcription pathway
0.0	0.8	REACTOME MRNA 3 END PROCESSING	Genes involved in mRNA 3'-end processing
0.0	0.5	REACTOME ACYL CHAIN REMODELLING OF PC	Genes involved in Acyl chain remodelling of PC
0.0	0.1	REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING	Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0	0.4	REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS	Genes involved in Termination of O-glycan biosynthesis
0.0	0.2	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.2	REACTOME INTRINSIC PATHWAY FOR APOPTOSIS	Genes involved in Intrinsic Pathway for Apoptosis
0.0	0.6	REACTOME O LINKED GLYCOSYLATION OF MUCINS	Genes involved in O-linked glycosylation of mucins
0.0	0.4	REACTOME CGMP EFFECTS	Genes involved in cGMP effects
0.0	0.2	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.0	REACTOME NGF SIGNALLING VIA TRKA FROM THE PLASMA MEMBRANE	Genes involved in NGF signalling via TRKA from the plasma membrane
0.0	0.3	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.0	0.2	REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS	Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0	0.4	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.5	REACTOME HS GAG BIOSYNTHESIS	Genes involved in HS-GAG biosynthesis
0.0	0.2	REACTOME CRMPS IN SEMA3A SIGNALING	Genes involved in CRMPs in Sema3A signaling
0.0	0.5	REACTOME ION TRANSPORT BY P TYPE ATPASES	Genes involved in Ion transport by P-type ATPases
0.0	0.2	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR
0.0	0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	0.3	REACTOME KINESINS	Genes involved in Kinesins
0.0	0.2	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.7	REACTOME MITOCHONDRIAL PROTEIN IMPORT	Genes involved in Mitochondrial Protein Import
0.0	0.1	REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND	Genes involved in Removal of the Flap Intermediate from the C-strand
0.0	0.1	REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS	Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0	0.1	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.0	0.3	REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT	Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.0	0.7	REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES	Genes involved in Loss of Nlp from mitotic centrosomes
0.0	0.0	REACTOME ADP SIGNALLING THROUGH P2RY1	Genes involved in ADP signalling through P2Y purinoceptor 1
0.0	0.1	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0	1.0	REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS	Genes involved in Class B/2 (Secretin family receptors)
0.0	0.1	REACTOME TRANSPORT OF ORGANIC ANIONS	Genes involved in Transport of organic anions
0.0	0.1	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.0	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.2	REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE	Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0	0.2	REACTOME ADHERENS JUNCTIONS INTERACTIONS	Genes involved in Adherens junctions interactions
0.0	0.6	REACTOME RESPIRATORY ELECTRON TRANSPORT	Genes involved in Respiratory electron transport
0.0	0.1	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease

Results for Tfap2d

Z-value: 2.37

Motif logo

Transcription factors associated with Tfap2d

Activity of the Tfap2d motif across conditions

Conditions sorted by the z-value of the Tfap2d motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2d

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: