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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Tfap2e

Z-value: 0.71

Motif logo

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Transcription factors associated with Tfap2e

Gene Symbol Gene ID Gene Info
Tfap2e
ENSMUSG00000042477.7 transcription factor AP-2, epsilon

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr4_126733083_126733252Tfap2e30730.1815580.711.1e-01Click!
chr4_126708617_126708772Tfap2e275460.1075110.691.3e-01Click!
chr4_126741521_126741686Tfap2e53630.1437970.078.9e-01Click!

Activity of the Tfap2e motif across conditions

Conditions sorted by the z-value of the Tfap2e motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr6_116636671_116636829 0.65 Rassf4
 Ras association (RalGDS/AF-6) domain family member 4
 4252
 0.12
chr12_112109668_112109994 0.58 Mir3073b
 microRNA 3073b
 522
 0.45
chr2_29750814_29750965 0.53 Gm13420
 predicted gene 13420
 796
 0.47
chr13_54402403_54402557 0.43 Gm16248
 predicted gene 16248
 3146
 0.22
chr9_115456234_115456417 0.43 Gm5921
 predicted gene 5921
 17744
 0.16
chr11_94390636_94390799 0.43 Abcc3
 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
 2203
 0.26
chr17_56681920_56682093 0.39 Ranbp3
 RAN binding protein 3
 8622
 0.11
chr2_145813125_145813276 0.38 Rin2
 Ras and Rab interactor 2
 8950
 0.22
chr19_54071291_54071462 0.38 Gm50186
 predicted gene, 50186
 13183
 0.18
chr3_108782866_108783017 0.37 Stxbp3
 syntaxin binding protein 3
 14843
 0.14
chr5_117285355_117285646 0.33 Pebp1
 phosphatidylethanolamine binding protein 1
 2025
 0.19
chr12_102295217_102295408 0.33 Rin3
 Ras and Rab interactor 3
 11671
 0.22
chr13_32897014_32897418 0.30 Serpinb1c
 serine (or cysteine) peptidase inhibitor, clade B, member 1c
 941
 0.49
chr1_72833711_72833862 0.30 Igfbp2
 insulin-like growth factor binding protein 2
 8464
 0.22
chr19_25387114_25387309 0.30 Kank1
 KN motif and ankyrin repeat domains 1
 8092
 0.22
chr17_29045019_29045203 0.29 Srsf3
 serine and arginine-rich splicing factor 3
 5417
 0.09
chr10_80957966_80958144 0.28 Gm3828
 predicted gene 3828
 3345
 0.13
chr9_95580937_95581120 0.28 Paqr9
 progestin and adipoQ receptor family member IX
 21371
 0.11
chr11_64599304_64599471 0.27 Gm24275
 predicted gene, 24275
 8747
 0.3
chr12_110992829_110992984 0.26 6030440G07Rik
 RIKEN cDNA 6030440G07 gene
 1492
 0.27
chr19_34772591_34773080 0.26 Gm50173
 predicted gene, 50173
 1046
 0.4
chr19_30331979_30332136 0.26 Gm24108
 predicted gene, 24108
 70540
 0.11
chr2_39003650_39003831 0.26 Rpl35
 ribosomal protein L35
 1303
 0.23
chr6_73221980_73222151 0.26 Dnah6
 dynein, axonemal, heavy chain 6
 414
 0.72
chr11_53419604_53419795 0.26 Leap2
 liver-expressed antimicrobial peptide 2
 3471
 0.1
chr12_102437143_102437359 0.25 Lgmn
 legumain
 2562
 0.25
chr16_18877584_18877767 0.25 Hira
 histone cell cycle regulator
 263
 0.79
chr14_61037704_61037855 0.24 Tnfrsf19
 tumor necrosis factor receptor superfamily, member 19
 112
 0.6
chr2_153657078_153657257 0.24 Dnmt3bos
 DNA methyltransferase 3B, opposite strand
 6881
 0.16
chr16_23989631_23990067 0.23 Bcl6
 B cell leukemia/lymphoma 6
 997
 0.42
chr18_46716349_46716534 0.23 Cdo1
 cysteine dioxygenase 1, cytosolic
 11588
 0.13
chr9_67614466_67614621 0.22 Tln2
 talin 2
 54840
 0.12
chr5_114889052_114889221 0.22 Oasl2
 2'-5' oligoadenylate synthetase-like 2
 7800
 0.08
chr2_129489606_129489767 0.22 Gm14040
 predicted gene 14040
 26121
 0.15
chr4_59548512_59548664 0.21 Ptbp3
 polypyrimidine tract binding protein 3
 149
 0.84
chr7_84167720_84167916 0.20 Gm22177
 predicted gene, 22177
 2747
 0.21
chr1_39591675_39591839 0.20 Gm5100
 predicted gene 5100
 6248
 0.13
chr2_154609281_154609723 0.20 Zfp341
 zinc finger protein 341
 3795
 0.12
chr12_84206331_84206483 0.20 Gm47447
 predicted gene, 47447
 9730
 0.1
chr11_61564668_61564834 0.20 Epn2
 epsin 2
 14907
 0.14
chr5_9043706_9043857 0.20 Gm40264
 predicted gene, 40264
 8657
 0.15
chr16_95827519_95827681 0.20 1600002D24Rik
 RIKEN cDNA 1600002D24 gene
 18170
 0.16
chr13_92469480_92469792 0.19 Fam151b
 family with sequence similarity 151, member B
 14377
 0.17
chr1_165768492_165768643 0.19 Creg1
 cellular repressor of E1A-stimulated genes 1
 909
 0.37
chr17_63493519_63493696 0.19 Fbxl17
 F-box and leucine-rich repeat protein 17
 854
 0.7
chr9_70657719_70657882 0.19 Mindy2
 MINDY lysine 48 deubiquitinase 2
 626
 0.63
chr4_31426757_31426908 0.19 Gm11922
 predicted gene 11922
 46360
 0.2
chr8_71680518_71680684 0.19 Jak3
 Janus kinase 3
 2266
 0.14
chr3_145780988_145781495 0.18 Ddah1
 dimethylarginine dimethylaminohydrolase 1
 20493
 0.19
chr19_41911790_41911957 0.18 Pgam1
 phosphoglycerate mutase 1
 50
 0.95
chr5_138779730_138779904 0.18 Fam20c
 family with sequence similarity 20, member C
 6683
 0.2
chr10_94119877_94120030 0.18 Gm48372
 predicted gene, 48372
 11214
 0.13
chr1_190174350_190174513 0.17 Prox1
 prospero homeobox 1
 3717
 0.22
chr19_34804924_34805353 0.17 Gm50116
 predicted gene, 50116
 876
 0.48
chr19_12634142_12634556 0.17 Glyat
 glycine-N-acyltransferase
 816
 0.44
chr19_6952737_6952905 0.17 Plcb3
 phospholipase C, beta 3
 2026
 0.12
chr14_73382885_73383301 0.17 Itm2b
 integral membrane protein 2B
 2105
 0.33
chr13_60493839_60494263 0.17 A530001N23Rik
 RIKEN cDNA A530001N23 gene
 5243
 0.18
chr5_88929617_88929827 0.17 Slc4a4
 solute carrier family 4 (anion exchanger), member 4
 4810
 0.28
chr18_46698271_46698422 0.17 Cdo1
 cysteine dioxygenase 1, cytosolic
 29683
 0.11
chr5_32092059_32092277 0.17 Babam2
 BRISC and BRCA1 A complex member 2
 12471
 0.17
chr9_33068372_33068541 0.16 Gm27166
 predicted gene 27166
 36665
 0.17
chr19_4821405_4821565 0.16 Ccs
 copper chaperone for superoxide dismutase
 4524
 0.09
chr3_95625229_95625406 0.16 Ensa
 endosulfine alpha
 291
 0.8
chr18_31884190_31884397 0.16 Wdr33
 WD repeat domain 33
 2151
 0.25
chr10_84811233_84811541 0.16 Gm24226
 predicted gene, 24226
 204
 0.95
chr2_148872952_148873130 0.16 Cst3
 cystatin C
 2410
 0.19
chr5_122274917_122275081 0.16 Pptc7
 PTC7 protein phosphatase homolog
 9366
 0.11
chr18_12647726_12648094 0.15 Gm41668
 predicted gene, 41668
 509
 0.72
chr3_83994327_83994478 0.15 Tmem131l
 transmembrane 131 like
 26174
 0.21
chr12_71719042_71719430 0.15 Gm47555
 predicted gene, 47555
 35149
 0.17
chr2_119355713_119355881 0.15 Chac1
 ChaC, cation transport regulator 1
 4568
 0.16
chr9_51961247_51961723 0.15 Fdx1
 ferredoxin 1
 2061
 0.29
chr10_7212691_7212859 0.15 Cnksr3
 Cnksr family member 3
 538
 0.86
chr10_77693450_77693640 0.15 Gm19402
 predicted gene, 19402
 2788
 0.08
chr5_99994276_99994439 0.15 Gm17092
 predicted gene 17092
 15296
 0.13
chr12_78265748_78266376 0.15 Gm48225
 predicted gene, 48225
 4769
 0.18
chr10_75222636_75222997 0.15 Specc1l
 sperm antigen with calponin homology and coiled-coil domains 1-like
 7039
 0.21
chr13_46883271_46883538 0.15 Gm48250
 predicted gene, 48250
 2377
 0.23
chr9_43467006_43467175 0.15 Gm28215
 predicted gene 28215
 2332
 0.29
chr6_117612056_117612213 0.15 Gm45083
 predicted gene 45083
 436
 0.85
chr14_20298249_20298415 0.14 Nudt13
 nudix (nucleoside diphosphate linked moiety X)-type motif 13
 2170
 0.22
chr17_25221206_25221426 0.14 Unkl
 unkempt family like zinc finger
 1223
 0.25
chr4_57845057_57845232 0.14 Pakap
 paralemmin A kinase anchor protein
 103
 0.97
chr5_118596025_118596197 0.14 Gm43788
 predicted gene 43788
 6605
 0.16
chr2_104002844_104003003 0.14 Fbxo3
 F-box protein 3
 24798
 0.1
chr4_135989135_135989286 0.14 Pithd1
 PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
 1946
 0.16
chr8_11636365_11636526 0.14 Ankrd10
 ankyrin repeat domain 10
 688
 0.29
chr7_139364090_139364263 0.14 Inpp5a
 inositol polyphosphate-5-phosphatase A
 24933
 0.19
chr15_102721608_102721977 0.14 Calcoco1
 calcium binding and coiled coil domain 1
 339
 0.84
chr11_7196610_7196788 0.14 Igfbp1
 insulin-like growth factor binding protein 1
 1083
 0.48
chr11_95687340_95687492 0.14 Gm9796
 predicted gene 9796
 11727
 0.12
chr18_32136413_32136564 0.14 Proc
 protein C
 742
 0.51
chr1_164307490_164307653 0.14 Blzf1
 basic leucine zipper nuclear factor 1
 82
 0.52
chr1_69106645_69106814 0.14 Gm16076
 predicted gene 16076
 11
 0.96
chr10_128298417_128298592 0.14 Il23a
 interleukin 23, alpha subunit p19
 248
 0.74
chr7_27478150_27478347 0.14 Sertad3
 SERTA domain containing 3
 4480
 0.1
chr13_83064851_83065002 0.14 2310067P03Rik
 RIKEN cDNA 2310067P03 gene
 531
 0.88
chr6_73222805_73223119 0.14 Gm40377
 predicted gene, 40377
 88
 0.95
chr1_190847941_190848107 0.14 Rps6kc1
 ribosomal protein S6 kinase polypeptide 1
 3440
 0.28
chr11_121500753_121500917 0.14 Tbcd
 tubulin-specific chaperone d
 799
 0.61
chr2_160210649_160210800 0.13 Gm826
 predicted gene 826
 102892
 0.07
chr16_30255365_30255526 0.13 Gm49645
 predicted gene, 49645
 293
 0.87
chr17_32364458_32364626 0.13 Wiz
 widely-interspaced zinc finger motifs
 79
 0.95
chr19_6243342_6243519 0.13 Atg2a
 autophagy related 2A
 1762
 0.16
chr17_79715662_79715994 0.13 Cyp1b1
 cytochrome P450, family 1, subfamily b, polypeptide 1
 767
 0.62
chr14_31929383_31929549 0.13 D830044D21Rik
 RIKEN cDNA D830044D21 gene
 22938
 0.17
chr8_126685352_126685531 0.13 Gm45805
 predicted gene 45805
 72893
 0.1
chr9_80026313_80026485 0.13 Filip1
 filamin A interacting protein 1
 13548
 0.14
chr1_166032024_166032183 0.13 Gm7626
 predicted gene 7626
 11588
 0.15
chr9_64053601_64053804 0.13 Gm25606
 predicted gene, 25606
 5206
 0.14
chr10_115479053_115479225 0.13 Lgr5
 leucine rich repeat containing G protein coupled receptor 5
 16060
 0.19
chr15_85709424_85709582 0.13 Mirlet7b
 microRNA let7b
 2184
 0.21
chr9_46053003_46053558 0.13 Sik3
 SIK family kinase 3
 40280
 0.11
chr11_75689615_75689766 0.13 Crk
 v-crk avian sarcoma virus CT10 oncogene homolog
 10148
 0.13
chr4_44997094_44997250 0.13 1700055D18Rik
 RIKEN cDNA 1700055D18 gene
 14515
 0.1
chr4_145037079_145037530 0.13 Vps13d
 vacuolar protein sorting 13D
 13730
 0.24
chr4_139373277_139373435 0.13 Ubr4
 ubiquitin protein ligase E3 component n-recognin 4
 7303
 0.1
chr6_88292396_88292777 0.13 Gm44265
 predicted gene, 44265
 61020
 0.08
chr4_104973013_104973233 0.13 Gm12721
 predicted gene 12721
 2994
 0.33
chr8_71375544_71375702 0.13 Nr2f6
 nuclear receptor subfamily 2, group F, member 6
 167
 0.89
chr10_69288238_69288393 0.13 Rhobtb1
 Rho-related BTB domain containing 1
 8857
 0.18
chr4_136248818_136248972 0.12 Tcea3
 transcription elongation factor A (SII), 3
 922
 0.5
chr6_108254587_108254738 0.12 Itpr1
 inositol 1,4,5-trisphosphate receptor 1
 1704
 0.47
chrX_100447303_100447475 0.12 Awat2
 acyl-CoA wax alcohol acyltransferase 2
 4672
 0.17
chr1_72226394_72226550 0.12 Gm25360
 predicted gene, 25360
 232
 0.89
chr9_62421178_62421341 0.12 Coro2b
 coronin, actin binding protein, 2B
 6742
 0.24
chr11_86921243_86921467 0.12 Ypel2
 yippee like 2
 50669
 0.12
chr8_70221071_70221246 0.12 Armc6
 armadillo repeat containing 6
 1132
 0.32
chr18_38180760_38180944 0.12 Pcdh1
 protocadherin 1
 22311
 0.12
chr8_124750214_124750687 0.12 Fam89a
 family with sequence similarity 89, member A
 1382
 0.3
chr8_93043146_93043627 0.12 Ces1a
 carboxylesterase 1A
 2283
 0.25
chr7_25390104_25390268 0.12 Lipe
 lipase, hormone sensitive
 80
 0.94
chr4_141131590_141132080 0.12 Szrd1
 SUZ RNA binding domain containing 1
 7892
 0.11
chr1_161247888_161248058 0.12 Prdx6
 peroxiredoxin 6
 2581
 0.25
chr10_77118262_77118451 0.12 Col18a1
 collagen, type XVIII, alpha 1
 4410
 0.2
chr18_20188219_20188403 0.12 Dsg1c
 desmoglein 1 gamma
 59029
 0.12
chr5_139499620_139499800 0.12 Zfand2a
 zinc finger, AN1-type domain 2A
 15161
 0.13
chr9_40805180_40805541 0.12 Snord14e
 small nucleolar RNA, C/D box 14E
 612
 0.38
chr12_30943371_30943530 0.12 Sh3yl1
 Sh3 domain YSC-like 1
 31263
 0.14
chr5_34187720_34187884 0.12 Mxd4
 Max dimerization protein 4
 82
 0.94
chr14_29996362_29996748 0.12 Il17rb
 interleukin 17 receptor B
 1904
 0.2
chr8_84743526_84743857 0.12 G430095P16Rik
 RIKEN cDNA G430095P16 gene
 20684
 0.09
chr12_104841328_104841498 0.11 4930408O17Rik
 RIKEN cDNA 4930408O17 gene
 15958
 0.18
chr10_41575979_41576291 0.11 5730435O14Rik
 RIKEN cDNA 5730435O14 gene
 571
 0.67
chr11_119913012_119913281 0.11 Chmp6
 charged multivesicular body protein 6
 295
 0.86
chr10_67025749_67025925 0.11 Gm31763
 predicted gene, 31763
 2528
 0.28
chr3_104360355_104360770 0.11 Gm5546
 predicted gene 5546
 6051
 0.18
chr17_25239677_25239863 0.11 Gnptg
 N-acetylglucosamine-1-phosphotransferase, gamma subunit
 346
 0.47
chr11_50137654_50137855 0.11 Tbc1d9b
 TBC1 domain family, member 9B
 2327
 0.18
chr8_22124586_22124925 0.11 Nek5
 NIMA (never in mitosis gene a)-related expressed kinase 5
 283
 0.87
chr8_84346540_84346704 0.11 Cacna1a
 calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
 7983
 0.14
chr15_100637292_100637581 0.11 Smagp
 small cell adhesion glycoprotein
 496
 0.61
chr8_70775755_70775922 0.11 Pik3r2
 phosphoinositide-3-kinase regulatory subunit 2
 841
 0.26
chr10_84416787_84416966 0.11 Nuak1
 NUAK family, SNF1-like kinase, 1
 23721
 0.15
chr5_122263936_122264091 0.11 Tctn1
 tectonic family member 1
 402
 0.76
chr12_46635586_46635767 0.11 Gm48535
 predicted gene, 48535
 30033
 0.15
chr9_80777245_80777426 0.11 Gm27224
 predicted gene 27224
 25316
 0.22
chr8_126808574_126808734 0.11 A630001O12Rik
 RIKEN cDNA A630001O12 gene
 30579
 0.17
chr18_69502311_69502466 0.11 Tcf4
 transcription factor 4
 1430
 0.53
chr19_46975598_46975758 0.11 Nt5c2
 5'-nucleotidase, cytosolic II
 6110
 0.17
chr13_75598831_75599007 0.11 Gm4149
 predicted pseudogene 4149
 45977
 0.1
chr4_62508801_62509208 0.11 Hdhd3
 haloacid dehalogenase-like hydrolase domain containing 3
 5537
 0.12
chr18_38283827_38284012 0.11 Pcdh12
 protocadherin 12
 438
 0.52
chr12_40580026_40580177 0.11 Dock4
 dedicator of cytokinesis 4
 133765
 0.05
chr1_58112957_58113355 0.11 Aox3
 aldehyde oxidase 3
 18
 0.98
chr13_67780014_67780192 0.11 Zfp493
 zinc finger protein 493
 349
 0.76
chr3_121291310_121291524 0.11 Alg14
 asparagine-linked glycosylation 14
 356
 0.84
chr6_99490333_99490484 0.11 Gm22328
 predicted gene, 22328
 5706
 0.22
chr17_14173768_14173919 0.10 Gm34510
 predicted gene, 34510
 29885
 0.13
chr14_66654420_66654619 0.10 Adra1a
 adrenergic receptor, alpha 1a
 18963
 0.22
chr4_135286870_135287040 0.10 Gm12983
 predicted gene 12983
 3720
 0.15
chr5_103738632_103738798 0.10 Aff1
 AF4/FMR2 family, member 1
 15447
 0.19
chr12_102647960_102648119 0.10 Itpk1
 inositol 1,3,4-triphosphate 5/6 kinase
 7105
 0.14
chr15_77924420_77924584 0.10 Txn2
 thioredoxin 2
 3233
 0.19
chr9_74921528_74921682 0.10 Fam214a
 family with sequence similarity 214, member A
 31279
 0.14
chr17_31391456_31391613 0.10 Pde9a
 phosphodiesterase 9A
 5240
 0.16
chr5_114581660_114581827 0.10 Fam222a
 family with sequence similarity 222, member A
 13726
 0.15
chr14_20138027_20138204 0.10 Saysd1
 SAYSVFN motif domain containing 1
 419
 0.81
chr10_24097646_24097797 0.10 Taar8c
 trace amine-associated receptor 8C
 4191
 0.1
chr4_148214912_148215063 0.10 Disp3
 dispatched RND transporter family member 3
 45764
 0.08
chr3_119783480_119783653 0.10 Ptbp2
 polypyrimidine tract binding protein 2
 125
 0.96
chr5_114435733_114435884 0.10 Mmab
 methylmalonic aciduria (cobalamin deficiency) cblB type homolog (human)
 8184
 0.14
chr5_74316665_74316828 0.10 Gm15981
 predicted gene 15981
 288
 0.89
chr8_119445523_119446899 0.10 Necab2
 N-terminal EF-hand calcium binding protein 2
 508
 0.74
chr7_115565335_115565528 0.10 Sox6
 SRY (sex determining region Y)-box 6
 32465
 0.24
chr2_166952238_166952420 0.10 Stau1
 staufen double-stranded RNA binding protein 1
 1098
 0.41
chr1_10212196_10212367 0.10 Arfgef1
 ADP-ribosylation factor guanine nucleotide-exchange factor 1(brefeldin A-inhibited)
 1932
 0.35
chrX_20819269_20819429 0.10 Gm24824
 predicted gene, 24824
 4465
 0.13
chr6_94357642_94357793 0.10 Gm19908
 predicted gene, 19908
 8183
 0.21
chr15_96699087_96699266 0.10 Slc38a2
 solute carrier family 38, member 2
 485
 0.66
chr4_97772221_97772394 0.10 Nfia
 nuclear factor I/A
 427
 0.84
chr15_64152976_64153142 0.10 Asap1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain1
 29253
 0.18
chr8_124275783_124275948 0.10 Galnt2
 polypeptide N-acetylgalactosaminyltransferase 2
 19238
 0.16
chr8_120295587_120295753 0.10 Gse1
 genetic suppressor element 1, coiled-coil protein
 67214
 0.09
chr12_24627702_24627853 0.10 Gm6969
 predicted pseudogene 6969
 11233
 0.15
chr7_100658408_100658565 0.10 Plekhb1
 pleckstrin homology domain containing, family B (evectins) member 1
 30
 0.96
chr17_13699350_13699759 0.09 Gm16046
 predicted gene 16046
 16038
 0.13
chr17_56470625_56470795 0.09 Ptprs
 protein tyrosine phosphatase, receptor type, S
 3917
 0.18
chr11_46579639_46579790 0.09 BC053393
 cDNA sequence BC053393
 8178
 0.13

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2e

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.0 0.1 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.1 GO:0019448 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.1 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.1 GO:0002930 trabecular meshwork development(GO:0002930)
0.0 0.1 GO:0051599 response to hydrostatic pressure(GO:0051599)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.0 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 0.1 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.1 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.1 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.0 0.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.0 0.0 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:0051601 exocyst localization(GO:0051601)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.0 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.1 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.0 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.0 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.0 0.0 GO:0071895 odontoblast differentiation(GO:0071895)
0.0 0.0 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0034724 DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.0 GO:0021590 cerebellum maturation(GO:0021590)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.0 GO:1903660 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.0 GO:0002159 desmosome assembly(GO:0002159)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.0 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.1 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.1 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.1 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0016842 amidine-lyase activity(GO:0016842)
0.0 0.1 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 0.1 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.0 0.1 GO:0003865 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.0 0.0 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.0 0.0 GO:0035514 DNA demethylase activity(GO:0035514)
0.0 0.1 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.0 GO:0015119 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.0 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0 0.0 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.0 GO:1904288 BAT3 complex binding(GO:1904288)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.1 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.0 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants