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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Tfap4

Z-value: 3.05

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Transcription factors associated with Tfap4

Gene Symbol	Gene ID	Gene Info
Tfap4 Ensembl NCBI MGI UniProt	ENSMUSG00000005718.7	transcription factor AP4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr16_4558253_4558537	Tfap4	388	0.798264	-0.89	1.9e-02	Click!
chr16_4568017_4568179	Tfap4	8244	0.129985	-0.85	3.0e-02	Click!
chr16_4558831_4559019	Tfap4	142	0.939695	-0.82	4.3e-02	Click!
chr16_4551146_4551303	Tfap4	1738	0.268735	-0.80	5.8e-02	Click!
chr16_4556948_4557262	Tfap4	1678	0.275527	0.77	7.3e-02	Click!

Activity of the Tfap4 motif across conditions

Conditions sorted by the z-value of the Tfap4 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr2_22587937_22588311	2.39	Gm13341	predicted gene 13341	162	0.91
chr8_11771715_11771875	1.80	Arhgef7	Rho guanine nucleotide exchange factor (GEF7)	10732	0.13
chr6_54760026_54760215	1.78	Znrf2	zinc and ring finger 2	56796	0.1
chr1_24615703_24615868	1.77	Gm28661	predicted gene 28661	220	0.62
chr1_88316276_88316427	1.76	Trpm8	transient receptor potential cation channel, subfamily M, member 8	2562	0.2
chr5_119295643_119295794	1.70	n-R5s175	nuclear encoded rRNA 5S 175	1527	0.52
chr16_94544597_94544776	1.53	Vps26c	VPS26 endosomal protein sorting factor C	17856	0.16
chr6_94547990_94548164	1.51	Slc25a26	solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 26	13937	0.2
chr13_52941058_52941231	1.50	Auh	AU RNA binding protein/enoyl-coenzyme A hydratase	11463	0.19
chr5_134170212_134170373	1.46	Rcc1l	reculator of chromosome condensation 1 like	917	0.46
chr8_40896761_40897111	1.39	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	1502	0.36
chr1_92683263_92683419	1.38	Gm29483	predicted gene 29483	33861	0.09
chr8_119399377_119399539	1.35	Mlycd	malonyl-CoA decarboxylase	4560	0.18
chr13_52236242_52236425	1.35	Gm48199	predicted gene, 48199	55922	0.15
chr7_138867340_138867520	1.35	Ppp2r2d	protein phosphatase 2, regulatory subunit B, delta	980	0.43
chr17_43270317_43270505	1.32	Adgrf1	adhesion G protein-coupled receptor F1	82	0.98
chr8_84351080_84351276	1.32	Cacna1a	calcium channel, voltage-dependent, P/Q type, alpha 1A subunit	12539	0.13
chr8_104681480_104681635	1.32	Gm7208	predicted gene 7208	654	0.5
chr4_149282086_149282263	1.32	Kif1b	kinesin family member 1B	25332	0.13
chr1_138967552_138967703	1.31	Dennd1b	DENN/MADD domain containing 1B	93	0.91
chr13_58478534_58478702	1.31	Gm47918	predicted gene, 47918	35597	0.12
chr1_184083178_184083366	1.30	Dusp10	dual specificity phosphatase 10	48891	0.15
chr17_84237228_84237457	1.29	Thada	thyroid adenoma associated	7482	0.19
chr8_3211565_3211796	1.29	Insr	insulin receptor	18963	0.18
chr3_30934508_30934659	1.29	Phc3	polyhomeotic 3	1472	0.36
chr15_39116967_39117141	1.25	Dcaf13	DDB1 and CUL4 associated factor 13	4189	0.15
chr15_8636103_8636280	1.24	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3	7056	0.21
chr5_75063247_75063407	1.23	Gsx2	GS homeobox 2	12274	0.11
chr9_31610718_31610869	1.23	Gm18820	predicted gene, 18820	32977	0.14
chr3_68508770_68508933	1.20	Schip1	schwannomin interacting protein 1	14643	0.22
chr16_57336835_57337010	1.20	Gm49579	predicted gene, 49579	1388	0.35
chr9_63662886_63663067	1.15	Smad3	SMAD family member 3	3571	0.25
chrX_102478577_102478728	1.14	Hdac8	histone deacetylase 8	26089	0.19
chr19_47357458_47357635	1.13	Sh3pxd2a	SH3 and PX domains 2A	42795	0.13
chr18_60619666_60619817	1.13	Synpo	synaptopodin	3584	0.21
chr15_59319862_59320035	1.13	Sqle	squalene epoxidase	4841	0.18
chr16_23026654_23026981	1.12	Kng2	kininogen 2	2192	0.15
chr2_163345083_163345234	1.10	Tox2	TOX high mobility group box family member 2	24780	0.15
chr13_80890166_80890317	1.10	Arrdc3	arrestin domain containing 3	137	0.95
chr3_117905348_117905499	1.09	Gm4321	predicted gene 4321	16409	0.2
chr10_19443791_19444052	1.08	Gm33104	predicted gene, 33104	42794	0.15
chr8_66386144_66386295	1.06	Marchf1	membrane associated ring-CH-type finger 1	75	0.96
chr7_65803535_65803728	1.06	1810008I18Rik	RIKEN cDNA 1810008I18 gene	400	0.85
chr6_72802247_72802403	1.06	Tcf7l1	transcription factor 7 like 1 (T cell specific, HMG box)	13071	0.17
chr8_104734602_104734788	1.04	Ces2a	carboxylesterase 2A	667	0.49
chr19_12488282_12488454	1.03	Dtx4	deltex 4, E3 ubiquitin ligase	13086	0.1
chr11_115803396_115803584	1.02	Caskin2	CASK-interacting protein 2	2609	0.14
chr4_95212952_95213103	1.01	Gm12708	predicted gene 12708	19665	0.2
chr13_73775744_73776073	1.01	Slc12a7	solute carrier family 12, member 7	12169	0.17
chr6_142668190_142668361	1.00	Abcc9	ATP-binding cassette, sub-family C (CFTR/MRP), member 9	33943	0.16
chr2_158783086_158783239	1.00	Fam83d	family with sequence similarity 83, member D	1754	0.34
chr1_170903440_170903816	0.99	Fcrlb	Fc receptor-like B	9313	0.09
chr11_61590567_61590914	0.99	Epn2	epsin 2	11053	0.16
chr13_52572559_52572762	0.99	Syk	spleen tyrosine kinase	10513	0.26
chr15_76552804_76552973	0.99	Slc52a2	solute carrier protein 52, member 2	13924	0.06
chr1_184060517_184060686	0.98	Dusp10	dual specificity phosphatase 10	26220	0.19
chr8_88792749_88792924	0.98	Rps6-ps2	ribosomal protein S6, pseudogene 2	13555	0.19
chr9_34258652_34258813	0.97	Gm27161	predicted gene 27161	58504	0.15
chr13_28502262_28502416	0.96	Gm6081	predicted gene 6081	8893	0.22
chr1_34388067_34388244	0.96	Gm5266	predicted gene 5266	20784	0.09
chr5_103591965_103592170	0.96	Gm15844	predicted gene 15844	32404	0.12
chr15_89478682_89478874	0.96	C230037L18Rik	RIKEN cDNA C230037L18 gene	1039	0.28
chr8_122574662_122574838	0.95	Aprt	adenine phosphoribosyl transferase	739	0.44
chr10_75098542_75098730	0.94	Bcr	BCR activator of RhoGEF and GTPase	38044	0.14
chr12_76527656_76527811	0.94	Plekhg3	pleckstrin homology domain containing, family G (with RhoGef domain) member 3	3158	0.17
chr9_12511948_12512243	0.93	Gm25365	predicted gene, 25365	268070	0.02
chr13_93940938_93941096	0.93	Gm24737	predicted gene, 24737	15293	0.17
chr8_46385009_46385281	0.93	Gm45253	predicted gene 45253	743	0.6
chr17_30010480_30010631	0.92	Zfand3	zinc finger, AN1-type domain 3	2758	0.19
chr17_47521688_47521855	0.92	Ccnd3	cyclin D3	16530	0.13
chr5_99233257_99233431	0.91	Rasgef1b	RasGEF domain family, member 1B	722	0.73
chr10_37231934_37232493	0.90	4930543K20Rik	RIKEN cDNA 4930543K20 gene	31535	0.2
chr2_6412718_6413019	0.90	Usp6nl	USP6 N-terminal like	8054	0.19
chr6_83636514_83636690	0.90	Clec4f	C-type lectin domain family 4, member f	19519	0.11
chr6_72058409_72058766	0.90	Gm8952	predicted gene 8952	15566	0.12
chr4_109204438_109204615	0.90	Osbpl9	oxysterol binding protein-like 9	2254	0.32
chr13_100837951_100838114	0.89	Slc30a5	solute carrier family 30 (zinc transporter), member 5	4605	0.15
chr18_68039394_68039559	0.89	Gm41764	predicted gene, 41764	78898	0.09
chr7_99848918_99849257	0.88	Spcs2	signal peptidase complex subunit 2 homolog (S. cerevisiae)	9772	0.11
chr1_13266872_13267045	0.87	Gm27881	predicted gene, 27881	4760	0.15
chr9_70940271_70940435	0.87	Lipc	lipase, hepatic	5545	0.22
chr9_43622435_43622586	0.87	Gm29909	predicted gene, 29909	14326	0.17
chr9_67584952_67585167	0.87	Tln2	talin 2	25356	0.21
chr5_54108584_54108907	0.87	Stim2	stromal interaction molecule 2	3377	0.3
chr6_83634127_83634281	0.86	Clec4f	C-type lectin domain family 4, member f	21917	0.1
chr14_31596523_31596674	0.86	Colq	collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase	5255	0.16
chr6_95684732_95684897	0.86	Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	8068	0.32
chr14_27178259_27178514	0.86	Gm7591	predicted gene 7591	32011	0.17
chr17_46162734_46163102	0.85	Gtpbp2	GTP binding protein 2	115	0.93
chr4_141955631_141955810	0.85	Fhad1	forkhead-associated (FHA) phosphopeptide binding domain 1	1526	0.3
chr4_150512381_150512639	0.85	Rere	arginine glutamic acid dipeptide (RE) repeats	24117	0.2
chr6_37633621_37633893	0.84	Ybx1-ps2	Y box protein 1, pseudogene 2	53438	0.14
chr3_83004838_83005211	0.84	Fgg	fibrinogen gamma chain	2700	0.2
chr7_68692846_68692997	0.84	Gm44692	predicted gene 44692	33546	0.17
chr7_123322507_123322658	0.84	Arhgap17	Rho GTPase activating protein 17	25992	0.17
chr8_80289362_80289553	0.84	Gm45430	predicted gene 45430	94258	0.08
chr11_101682592_101683066	0.83	Arl4d	ADP-ribosylation factor-like 4D	17288	0.09
chr11_69379820_69379976	0.83	Chd3	chromodomain helicase DNA binding protein 3	10492	0.07
chr15_66814050_66814231	0.83	Sla	src-like adaptor	1547	0.4
chr16_30664084_30664254	0.83	Fam43a	family with sequence similarity 43, member A	64446	0.1
chr8_40887865_40888040	0.81	Slc7a2	solute carrier family 7 (cationic amino acid transporter, y+ system), member 2	10486	0.16
chr12_112109668_112109994	0.81	Mir3073b	microRNA 3073b	522	0.45
chr1_151686797_151686981	0.81	Fam129a	family with sequence similarity 129, member A	9722	0.22
chr8_48755634_48755797	0.81	Tenm3	teneurin transmembrane protein 3	81025	0.1
chr13_42604431_42604611	0.81	Gm23086	predicted gene, 23086	20473	0.2
chr17_29487122_29487273	0.80	Pim1	proviral integration site 1	3556	0.13
chr17_13661332_13661537	0.80	2700054A10Rik	RIKEN cDNA 2700054A10 gene	7457	0.16
chr16_56063021_56063172	0.80	Gm24047	predicted gene, 24047	7467	0.12
chr7_130948986_130949137	0.80	Htra1	HtrA serine peptidase 1	5572	0.2
chr14_22759784_22759956	0.80	Gm7473	predicted gene 7473	15374	0.28
chr15_90343847_90344035	0.79	Gm36480	predicted gene, 36480	9765	0.28
chr1_151096269_151096457	0.79	Gm19087	predicted gene, 19087	11552	0.13
chr9_41447644_41447837	0.78	Mir100hg	Mir100 Mirlet7a-2 Mir125b-1 cluster host gene	27089	0.12
chr9_70318787_70318981	0.78	Mir5626	microRNA 5626	86869	0.07
chr17_34900013_34900177	0.78	Ehmt2	euchromatic histone lysine N-methyltransferase 2	401	0.55
chr1_194393815_194393986	0.78	4930503O07Rik	RIKEN cDNA 4930503O07 gene	171141	0.03
chr18_84376797_84376986	0.77	Gm37216	predicted gene, 37216	745	0.73
chr2_167292312_167292496	0.77	Gm11473	predicted gene 11473	10627	0.16
chr11_101714086_101714403	0.77	Dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8	18675	0.11
chr2_43692310_43692594	0.76	Kynu	kynureninase	21522	0.25
chr5_27251468_27251639	0.76	Dpp6	dipeptidylpeptidase 6	10422	0.23
chr18_60439116_60439291	0.76	BC023105	cDNA sequence BC023105	2562	0.23
chr12_54710776_54711011	0.76	Gm22634	predicted gene, 22634	585	0.45
chr11_84062884_84063069	0.76	Dusp14	dual specificity phosphatase 14	4104	0.2
chr5_30523230_30523387	0.75	Gm42765	predicted gene 42765	6149	0.14
chr11_115188803_115189002	0.75	Nat9	N-acetyltransferase 9 (GCN5-related, putative)	1043	0.32
chr14_16478758_16478933	0.75	Top2b	topoisomerase (DNA) II beta	53417	0.13
chr6_94729445_94729667	0.75	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	29398	0.17
chr11_84198102_84198302	0.75	Acaca	acetyl-Coenzyme A carboxylase alpha	2764	0.25
chr13_62883769_62883931	0.75	Fbp1	fructose bisphosphatase 1	4277	0.16
chr10_83323662_83323813	0.74	Slc41a2	solute carrier family 41, member 2	854	0.58
chr3_60845432_60845598	0.74	Gm36985	predicted gene, 36985	15192	0.19
chr2_147944279_147944645	0.74	9030622O22Rik	RIKEN cDNA 9030622O22 gene	31723	0.18
chrX_103994856_103995029	0.74	Gm14892	predicted gene 14892	6395	0.15
chr6_30300460_30300657	0.74	Ube2h	ubiquitin-conjugating enzyme E2H	3964	0.18
chr4_132494671_132494822	0.73	Gm12981	predicted gene 12981	14903	0.09
chr19_40499284_40499488	0.72	Sorbs1	sorbin and SH3 domain containing 1	11640	0.19
chr5_45482717_45482893	0.72	Lap3	leucine aminopeptidase 3	10569	0.12
chr1_190796699_190797018	0.72	Rps6kc1	ribosomal protein S6 kinase polypeptide 1	13605	0.24
chr12_112125883_112126333	0.72	Mir203	microRNA 203	4772	0.13
chr14_74792904_74793055	0.72	Lrch1	leucine-rich repeats and calponin homology (CH) domain containing 1	2012	0.38
chr12_110757292_110757448	0.72	Wdr20	WD repeat domain 20	19161	0.13
chr11_24789291_24789442	0.71	Gm10466	predicted gene 10466	58644	0.14
chr6_146887251_146887428	0.71	Ppfibp1	PTPRF interacting protein, binding protein 1 (liprin beta 1)	1148	0.43
chr8_126703674_126703836	0.71	Gm45805	predicted gene 45805	54579	0.14
chr7_34407626_34407781	0.71	Lsm14a	LSM14A mRNA processing body assembly factor	14388	0.11
chr1_179982265_179982426	0.71	Cdc42bpa	CDC42 binding protein kinase alpha	6446	0.22
chr13_39376380_39376556	0.71	Gm47348	predicted gene, 47348	64097	0.12
chr4_63221606_63221778	0.70	Col27a1	collagen, type XXVII, alpha 1	6257	0.18
chr6_128481052_128481238	0.70	Pzp	PZP, alpha-2-macroglobulin like	6710	0.09
chr5_143492763_143492920	0.70	Daglb	diacylglycerol lipase, beta	6163	0.13
chr6_71999990_72000187	0.70	Gm26628	predicted gene, 26628	36313	0.1
chr4_145187751_145187931	0.69	Vps13d	vacuolar protein sorting 13D	2825	0.32
chr1_131091558_131091726	0.69	Gm37084	predicted gene, 37084	507	0.72
chr3_95028684_95028835	0.69	Psmd4	proteasome (prosome, macropain) 26S subunit, non-ATPase, 4	5157	0.08
chr8_119436291_119436442	0.69	Osgin1	oxidative stress induced growth inhibitor 1	752	0.59
chr1_60735115_60735286	0.68	Cd28	CD28 antigen	11158	0.12
chr15_27596869_27597043	0.68	Otulin	OTU deubiquitinase with linear linkage specificity	11905	0.15
chr2_143940607_143940763	0.67	Rrbp1	ribosome binding protein 1	9051	0.17
chr2_122158376_122158599	0.67	Trim69	tripartite motif-containing 69	2213	0.19
chr3_49944802_49944974	0.67	Gm37854	predicted gene, 37854	57084	0.14
chr4_133561732_133562055	0.67	Gm23158	predicted gene, 23158	2944	0.13
chr17_69397260_69397453	0.67	Gm49894	predicted gene, 49894	13148	0.14
chr6_34874588_34874759	0.67	Tmem140	transmembrane protein 140	1959	0.2
chr5_122513930_122514081	0.67	Gm22965	predicted gene, 22965	7216	0.1
chr2_168005469_168005791	0.67	Gm14236	predicted gene 14236	4899	0.17
chr1_155794977_155795143	0.67	Qsox1	quiescin Q6 sulfhydryl oxidase 1	357	0.81
chr7_14416688_14417151	0.66	Sult2a8	sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 8	19528	0.14
chr1_164151464_164151642	0.66	F5	coagulation factor V	285	0.71
chr15_99846748_99846936	0.66	Lima1	LIM domain and actin binding 1	26699	0.07
chr2_132102821_132103020	0.66	Gm14052	predicted gene 14052	3051	0.22
chr12_28623362_28623536	0.66	Colec11	collectin sub-family member 11	72	0.96
chr5_151413141_151413328	0.65	1700028E10Rik	RIKEN cDNA 1700028E10 gene	6708	0.17
chr2_166622279_166622430	0.65	Prex1	phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1	16614	0.2
chr10_116208839_116209045	0.65	Ptprr	protein tyrosine phosphatase, receptor type, R	12546	0.22
chr9_69110052_69110233	0.65	Rora	RAR-related orphan receptor alpha	85399	0.1
chr13_56462943_56463109	0.65	Il9	interleukin 9	19220	0.14
chr11_20340873_20341031	0.64	Gm12033	predicted gene 12033	4939	0.2
chr3_9821630_9821800	0.64	Gm24786	predicted gene, 24786	8013	0.19
chr8_119434896_119435083	0.64	Osgin1	oxidative stress induced growth inhibitor 1	865	0.54
chr18_84037791_84037957	0.64	Tshz1	teashirt zinc finger family member 1	47201	0.11
chr12_54738012_54738197	0.64	Gm22317	predicted gene, 22317	518	0.54
chr15_87043510_87043661	0.64	Gm23416	predicted gene, 23416	25408	0.17
chr5_115508938_115509110	0.64	Pxn	paxillin	2168	0.14
chr16_4285409_4285565	0.63	Gm6142	predicted pseudogene 6142	35193	0.14
chr4_109433685_109433864	0.63	Ttc39a	tetratricopeptide repeat domain 39A	12832	0.16
chr1_175530120_175530271	0.63	Rgs7	regulator of G protein signaling 7	37695	0.15
chrX_70792837_70793020	0.63	Gm8410	predicted gene 8410	22061	0.21
chr8_126615919_126616193	0.63	Irf2bp2	interferon regulatory factor 2 binding protein 2	22070	0.21
chr6_38121187_38121348	0.63	Gm23231	predicted gene, 23231	2884	0.2
chr18_61357667_61357827	0.63	Gm25301	predicted gene, 25301	40066	0.1
chr10_21916464_21916630	0.63	Sgk1	serum/glucocorticoid regulated kinase 1	11923	0.19
chr8_119429067_119429280	0.62	Osgin1	oxidative stress induced growth inhibitor 1	4951	0.17
chr2_29627943_29628094	0.62	Rapgef1	Rap guanine nucleotide exchange factor (GEF) 1	8108	0.21
chr8_68025403_68025869	0.62	Gm22018	predicted gene, 22018	15296	0.22
chr5_139791972_139792146	0.62	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)	525	0.68
chr4_55938450_55938625	0.62	Gm12519	predicted gene 12519	55202	0.17
chr17_46809548_46809737	0.61	Bicral	BRD4 interacting chromatin remodeling complex associated protein like	2543	0.19
chr12_80080203_80080512	0.61	Gm36660	predicted gene, 36660	1077	0.43
chr11_3199558_3199729	0.61	Eif4enif1	eukaryotic translation initiation factor 4E nuclear import factor 1	2749	0.15

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	1.2	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.2	1.1	GO:1902837	amino acid import into cell(GO:1902837)
0.2	0.7	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.2	0.7	GO:0070966	nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2	0.5	GO:2001269	positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2	0.5	GO:1903336	negative regulation of vacuolar transport(GO:1903336)
0.2	0.5	GO:0036166	phenotypic switching(GO:0036166)
0.1	0.4	GO:0043096	purine nucleobase salvage(GO:0043096)
0.1	0.5	GO:0021590	cerebellum maturation(GO:0021590)
0.1	0.4	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.1	0.3	GO:0060266	negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1	0.3	GO:0035887	aortic smooth muscle cell differentiation(GO:0035887)
0.1	0.4	GO:0050955	thermoception(GO:0050955)
0.1	0.4	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1	0.3	GO:0051182	coenzyme transport(GO:0051182)
0.1	0.3	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.1	0.3	GO:0046544	development of secondary male sexual characteristics(GO:0046544)
0.1	0.3	GO:0089700	protein kinase D signaling(GO:0089700)
0.1	0.4	GO:0019249	lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.1	0.3	GO:0043366	beta selection(GO:0043366)
0.1	0.3	GO:0006868	glutamine transport(GO:0006868)
0.1	0.3	GO:0070777	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.1	0.2	GO:0061341	non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1	0.3	GO:0003273	cell migration involved in endocardial cushion formation(GO:0003273)
0.1	0.3	GO:1900127	positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.1	0.7	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.1	0.2	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.1	0.4	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.1	0.2	GO:0071502	cellular response to temperature stimulus(GO:0071502)
0.1	0.3	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	0.2	GO:0071286	cellular response to magnesium ion(GO:0071286)
0.1	0.2	GO:0021827	cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.1	0.2	GO:0008626	granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1	0.1	GO:0003162	atrioventricular node development(GO:0003162)
0.1	0.2	GO:0045897	regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1	0.4	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.1	0.1	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.1	0.4	GO:0006689	ganglioside catabolic process(GO:0006689)
0.1	0.3	GO:0051639	actin filament network formation(GO:0051639)
0.1	0.3	GO:0061156	pulmonary artery morphogenesis(GO:0061156)
0.1	0.2	GO:0006564	L-serine biosynthetic process(GO:0006564)
0.1	0.2	GO:0035054	embryonic heart tube anterior/posterior pattern specification(GO:0035054)
0.1	0.3	GO:0019087	transformation of host cell by virus(GO:0019087)
0.0	0.2	GO:0015886	heme transport(GO:0015886)
0.0	0.2	GO:0043380	regulation of memory T cell differentiation(GO:0043380)
0.0	0.2	GO:0043402	glucocorticoid mediated signaling pathway(GO:0043402)
0.0	0.1	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0097503	sialylation(GO:0097503)
0.0	0.9	GO:0051642	centrosome localization(GO:0051642)
0.0	0.1	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.7	GO:0032011	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0034163	regulation of toll-like receptor 9 signaling pathway(GO:0034163)
0.0	0.4	GO:0042090	interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0	0.1	GO:0060061	Spemann organizer formation(GO:0060061)
0.0	0.1	GO:0070889	platelet alpha granule organization(GO:0070889)
0.0	0.1	GO:0003431	growth plate cartilage chondrocyte development(GO:0003431)
0.0	0.4	GO:0046337	phosphatidylethanolamine metabolic process(GO:0046337)
0.0	0.2	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.3	GO:0043615	astrocyte cell migration(GO:0043615)
0.0	0.1	GO:0033058	directional locomotion(GO:0033058)
0.0	0.1	GO:2000645	negative regulation of receptor catabolic process(GO:2000645)
0.0	0.3	GO:0051549	regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
0.0	0.2	GO:0000492	small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0	0.0	GO:0051081	membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0	0.1	GO:1903416	response to glycoside(GO:1903416)
0.0	0.0	GO:0045590	negative regulation of regulatory T cell differentiation(GO:0045590)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.1	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.2	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.2	GO:0060623	regulation of chromosome condensation(GO:0060623)
0.0	0.3	GO:0000059	protein import into nucleus, docking(GO:0000059)
0.0	0.2	GO:1990414	replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0	0.2	GO:0000966	RNA 5'-end processing(GO:0000966)
0.0	0.1	GO:0045404	positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.0	0.2	GO:0050847	progesterone receptor signaling pathway(GO:0050847)
0.0	0.3	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:1904430	negative regulation of t-circle formation(GO:1904430)
0.0	0.2	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0	0.1	GO:0034134	toll-like receptor 2 signaling pathway(GO:0034134)
0.0	0.2	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0	0.2	GO:0071557	histone H3-K27 demethylation(GO:0071557)
0.0	0.2	GO:0008582	regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0	0.4	GO:0046130	purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0	0.2	GO:0034116	positive regulation of heterotypic cell-cell adhesion(GO:0034116)
0.0	0.1	GO:0030538	embryonic genitalia morphogenesis(GO:0030538)
0.0	0.1	GO:0006222	UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0	0.0	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0071922	establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0	0.1	GO:0032430	positive regulation of phospholipase A2 activity(GO:0032430)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.2	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.1	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.1	GO:2000173	negative regulation of branching morphogenesis of a nerve(GO:2000173)
0.0	0.1	GO:1903279	regulation of calcium:sodium antiporter activity(GO:1903279)
0.0	0.1	GO:0034628	nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0	0.4	GO:0001553	luteinization(GO:0001553)
0.0	0.1	GO:0090526	regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0	0.0	GO:0097167	circadian regulation of translation(GO:0097167)
0.0	0.1	GO:0006059	hexitol metabolic process(GO:0006059)
0.0	0.2	GO:0033572	transferrin transport(GO:0033572)
0.0	0.3	GO:0006012	galactose metabolic process(GO:0006012)
0.0	0.1	GO:0015860	purine nucleoside transmembrane transport(GO:0015860) purine-containing compound transmembrane transport(GO:0072530) nucleoside transmembrane transport(GO:1901642)
0.0	0.1	GO:0010534	regulation of activation of JAK2 kinase activity(GO:0010534)
0.0	0.2	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.0	GO:0070350	white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350)
0.0	0.0	GO:2001137	positive regulation of endocytic recycling(GO:2001137)
0.0	0.1	GO:0048207	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.1	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0	0.0	GO:0060268	negative regulation of respiratory burst(GO:0060268)
0.0	0.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.0	0.3	GO:0000103	sulfate assimilation(GO:0000103)
0.0	0.2	GO:0070561	vitamin D receptor signaling pathway(GO:0070561)
0.0	0.4	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.0	0.3	GO:0051132	NK T cell activation(GO:0051132)
0.0	0.1	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.0	0.1	GO:0035405	histone-threonine phosphorylation(GO:0035405)
0.0	0.1	GO:1904694	negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0	0.1	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.2	GO:0006824	cobalt ion transport(GO:0006824)
0.0	0.2	GO:0031666	positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0	0.1	GO:0015684	ferrous iron transport(GO:0015684)
0.0	0.0	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0034080	CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0	0.1	GO:0039663	fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0	0.1	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.1	GO:1904016	response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.0	0.1	GO:0003096	renal sodium ion transport(GO:0003096)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.1	GO:0003166	bundle of His development(GO:0003166)
0.0	0.6	GO:0001829	trophectodermal cell differentiation(GO:0001829)
0.0	0.1	GO:0030167	proteoglycan catabolic process(GO:0030167)
0.0	0.2	GO:0003376	sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0	0.1	GO:0016344	meiotic chromosome movement towards spindle pole(GO:0016344) chromosome movement towards spindle pole(GO:0051305)
0.0	0.3	GO:0009083	branched-chain amino acid catabolic process(GO:0009083)
0.0	0.1	GO:0014057	positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0	0.2	GO:1990126	retrograde transport, endosome to plasma membrane(GO:1990126)
0.0	0.1	GO:0015770	disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0	0.3	GO:0090231	regulation of spindle checkpoint(GO:0090231)
0.0	0.1	GO:0032929	negative regulation of superoxide anion generation(GO:0032929)
0.0	0.3	GO:0051901	positive regulation of mitochondrial depolarization(GO:0051901)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.1	GO:0060926	cardiac pacemaker cell development(GO:0060926)
0.0	0.2	GO:0043102	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.2	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.1	GO:0070842	aggresome assembly(GO:0070842)
0.0	0.1	GO:0001827	inner cell mass cell fate commitment(GO:0001827)
0.0	0.2	GO:0035520	monoubiquitinated protein deubiquitination(GO:0035520)
0.0	0.6	GO:0035458	cellular response to interferon-beta(GO:0035458)
0.0	0.1	GO:0052490	negative regulation by symbiont of host apoptotic process(GO:0033668) negative regulation by symbiont of host programmed cell death(GO:0052041) negative regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052490)
0.0	0.0	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.0	GO:0046122	purine deoxyribonucleoside metabolic process(GO:0046122)
0.0	0.2	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.1	GO:0034184	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0097070	ductus arteriosus closure(GO:0097070)
0.0	0.1	GO:0002023	reduction of food intake in response to dietary excess(GO:0002023)
0.0	0.1	GO:0046600	negative regulation of centriole replication(GO:0046600)
0.0	0.3	GO:0006544	glycine metabolic process(GO:0006544)
0.0	0.1	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:0051697	protein delipidation(GO:0051697)
0.0	0.1	GO:0016078	tRNA catabolic process(GO:0016078)
0.0	0.1	GO:1900454	positive regulation of long term synaptic depression(GO:1900454)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.1	GO:0061304	retinal blood vessel morphogenesis(GO:0061304)
0.0	0.0	GO:0090259	regulation of retinal ganglion cell axon guidance(GO:0090259)
0.0	0.1	GO:0030213	hyaluronan biosynthetic process(GO:0030213)
0.0	0.1	GO:0006621	protein retention in ER lumen(GO:0006621)
0.0	0.1	GO:0036394	amylase secretion(GO:0036394)
0.0	0.1	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0	0.1	GO:0048739	cardiac muscle fiber development(GO:0048739)
0.0	0.1	GO:0046487	glyoxylate metabolic process(GO:0046487)
0.0	0.2	GO:0010839	negative regulation of keratinocyte proliferation(GO:0010839)
0.0	0.1	GO:0019287	isopentenyl diphosphate biosynthetic process(GO:0009240) isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0	0.0	GO:0002314	germinal center B cell differentiation(GO:0002314)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:0051964	negative regulation of synapse assembly(GO:0051964)
0.0	0.1	GO:0035360	positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0	0.1	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.4	GO:0010107	potassium ion import(GO:0010107)
0.0	0.1	GO:0090043	regulation of tubulin deacetylation(GO:0090043)
0.0	0.1	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0019262	N-acetylneuraminate catabolic process(GO:0019262)
0.0	0.0	GO:0002874	chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0072179	nephric duct formation(GO:0072179)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0090240	positive regulation of histone H4 acetylation(GO:0090240)
0.0	0.0	GO:0060594	mammary gland specification(GO:0060594)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0070094	positive regulation of glucagon secretion(GO:0070094)
0.0	0.1	GO:0006172	ADP biosynthetic process(GO:0006172)
0.0	0.0	GO:0002018	renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0	0.1	GO:1900452	regulation of long term synaptic depression(GO:1900452)
0.0	0.1	GO:1903966	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.1	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.0	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.1	GO:0051534	negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0	0.1	GO:0019364	pyridine nucleotide catabolic process(GO:0019364)
0.0	0.1	GO:0035435	phosphate ion transmembrane transport(GO:0035435)
0.0	0.1	GO:0017182	peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0	0.1	GO:0070831	basement membrane assembly(GO:0070831)
0.0	0.0	GO:2001170	negative regulation of ATP biosynthetic process(GO:2001170)
0.0	0.1	GO:0022028	tangential migration from the subventricular zone to the olfactory bulb(GO:0022028)
0.0	0.1	GO:1902510	regulation of apoptotic DNA fragmentation(GO:1902510)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.1	GO:0015705	iodide transport(GO:0015705)
0.0	0.1	GO:0018199	peptidyl-glutamine modification(GO:0018199)
0.0	0.1	GO:0030950	establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0	0.2	GO:0045324	late endosome to vacuole transport(GO:0045324)
0.0	0.0	GO:0036016	response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0	0.2	GO:0006072	glycerol-3-phosphate metabolic process(GO:0006072)
0.0	0.3	GO:0048268	clathrin coat assembly(GO:0048268)
0.0	0.1	GO:0061366	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.1	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.0	GO:0061205	paramesonephric duct development(GO:0061205)
0.0	0.1	GO:0045585	regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0	0.1	GO:0060316	positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0	0.1	GO:1903301	positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0	0.0	GO:0034136	negative regulation of toll-like receptor 2 signaling pathway(GO:0034136)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:1902459	positive regulation of stem cell population maintenance(GO:1902459)
0.0	0.1	GO:0051151	negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0	0.2	GO:0051386	regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0	0.1	GO:0097039	protein linear polyubiquitination(GO:0097039)
0.0	0.1	GO:1901026	ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.1	GO:0070535	histone H2A K63-linked ubiquitination(GO:0070535)
0.0	0.2	GO:0035518	histone H2A monoubiquitination(GO:0035518)
0.0	0.1	GO:0018211	protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0	0.2	GO:0071380	cellular response to prostaglandin E stimulus(GO:0071380)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0070340	detection of bacterial lipopeptide(GO:0070340)
0.0	0.4	GO:0016242	negative regulation of macroautophagy(GO:0016242)
0.0	0.2	GO:0034643	establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.0	0.1	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.5	GO:0015991	energy coupled proton transmembrane transport, against electrochemical gradient(GO:0015988) ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0	0.1	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719)
0.0	0.1	GO:0045136	development of secondary sexual characteristics(GO:0045136)
0.0	0.1	GO:0000183	chromatin silencing at rDNA(GO:0000183)
0.0	0.1	GO:1903587	regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0	0.1	GO:0006106	fumarate metabolic process(GO:0006106)
0.0	0.2	GO:0001921	positive regulation of receptor recycling(GO:0001921)
0.0	0.1	GO:0044821	telomere tethering at nuclear periphery(GO:0034398) meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0	0.0	GO:2000402	negative regulation of lymphocyte migration(GO:2000402)
0.0	0.1	GO:0021798	forebrain dorsal/ventral pattern formation(GO:0021798)
0.0	0.0	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0	0.1	GO:1901836	regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901836)
0.0	0.1	GO:1901387	positive regulation of voltage-gated calcium channel activity(GO:1901387)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:0048387	negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0	0.1	GO:0046641	positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0	0.2	GO:0007250	activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0	0.1	GO:1904869	protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0	0.0	GO:0034627	'de novo' NAD biosynthetic process(GO:0034627)
0.0	0.1	GO:0014835	myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.0	0.1	GO:0009235	cobalamin metabolic process(GO:0009235)
0.0	0.1	GO:0018101	protein citrullination(GO:0018101)
0.0	0.0	GO:1902075	cellular response to salt(GO:1902075)
0.0	0.2	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043518)
0.0	0.1	GO:0036233	glycine import(GO:0036233)
0.0	0.0	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.1	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.0	0.0	GO:0050713	negative regulation of interleukin-1 beta secretion(GO:0050713)
0.0	0.0	GO:0034443	regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0	0.1	GO:0033634	positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0	0.0	GO:0035973	aggrephagy(GO:0035973)
0.0	0.0	GO:0036112	medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.0	0.0	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.0	0.1	GO:0043137	DNA replication, removal of RNA primer(GO:0043137)
0.0	0.1	GO:0061158	3'-UTR-mediated mRNA destabilization(GO:0061158)
0.0	0.2	GO:1900119	positive regulation of execution phase of apoptosis(GO:1900119)
0.0	0.1	GO:0048842	positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669)
0.0	0.3	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.1	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.1	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.1	GO:0070050	neuron cellular homeostasis(GO:0070050)
0.0	0.1	GO:0051418	interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0	0.0	GO:0002424	T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840)
0.0	0.1	GO:0060155	platelet dense granule organization(GO:0060155)
0.0	0.1	GO:0034983	peptidyl-lysine deacetylation(GO:0034983)
0.0	0.0	GO:0045472	response to ether(GO:0045472)
0.0	0.2	GO:0032288	myelin assembly(GO:0032288)
0.0	0.1	GO:2000384	regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.0	0.0	GO:0003331	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0	0.1	GO:0003056	regulation of vascular smooth muscle contraction(GO:0003056)
0.0	0.0	GO:0070314	G1 to G0 transition(GO:0070314)
0.0	0.0	GO:0061074	regulation of neural retina development(GO:0061074)
0.0	0.0	GO:0002726	positive regulation of T cell cytokine production(GO:0002726)
0.0	0.2	GO:0001833	inner cell mass cell proliferation(GO:0001833)
0.0	0.0	GO:0044337	canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0	0.1	GO:0000707	meiotic DNA recombinase assembly(GO:0000707)
0.0	0.2	GO:0031643	positive regulation of myelination(GO:0031643)
0.0	0.0	GO:2000969	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.0	GO:0044778	meiotic DNA integrity checkpoint(GO:0044778)
0.0	0.0	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0	0.0	GO:0061052	negative regulation of cell growth involved in cardiac muscle cell development(GO:0061052)
0.0	0.2	GO:0035994	response to muscle stretch(GO:0035994)
0.0	0.1	GO:0006369	termination of RNA polymerase II transcription(GO:0006369)
0.0	0.1	GO:0060059	embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0	0.2	GO:0031100	organ regeneration(GO:0031100)
0.0	0.1	GO:0048227	plasma membrane to endosome transport(GO:0048227)
0.0	0.0	GO:0034035	purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.0	0.0	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.0	GO:1903377	negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.0	0.1	GO:0060539	diaphragm development(GO:0060539)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:2001286	regulation of caveolin-mediated endocytosis(GO:2001286)
0.0	0.2	GO:0071260	cellular response to mechanical stimulus(GO:0071260)
0.0	0.0	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0051005	negative regulation of lipoprotein lipase activity(GO:0051005)
0.0	0.0	GO:0032831	regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831)
0.0	0.1	GO:0031274	positive regulation of pseudopodium assembly(GO:0031274)
0.0	0.0	GO:0032025	response to cobalt ion(GO:0032025)
0.0	0.0	GO:0048850	hypophysis morphogenesis(GO:0048850)
0.0	0.0	GO:1904058	positive regulation of sensory perception of pain(GO:1904058)
0.0	0.0	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627) regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902218) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0	0.1	GO:0044034	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:2000427	positive regulation of apoptotic cell clearance(GO:2000427)
0.0	0.0	GO:0051581	negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0	0.0	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.0	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0	0.0	GO:0007208	phospholipase C-activating serotonin receptor signaling pathway(GO:0007208)
0.0	0.1	GO:0070244	negative regulation of thymocyte apoptotic process(GO:0070244)
0.0	0.0	GO:2000828	regulation of parathyroid hormone secretion(GO:2000828)
0.0	0.0	GO:0002884	negative regulation of hypersensitivity(GO:0002884)
0.0	0.1	GO:0031119	tRNA pseudouridine synthesis(GO:0031119)
0.0	0.0	GO:0007403	glial cell fate determination(GO:0007403)
0.0	0.1	GO:0006561	proline biosynthetic process(GO:0006561)
0.0	0.1	GO:0036507	protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.0	0.1	GO:0007638	mechanosensory behavior(GO:0007638)
0.0	0.1	GO:0015868	purine ribonucleotide transport(GO:0015868)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0030836	positive regulation of actin filament depolymerization(GO:0030836)
0.0	0.0	GO:0042117	monocyte activation(GO:0042117)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:2001260	regulation of semaphorin-plexin signaling pathway(GO:2001260)
0.0	0.0	GO:0090271	positive regulation of fibroblast growth factor production(GO:0090271)
0.0	0.1	GO:2000676	positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0	0.0	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0	0.1	GO:0060124	positive regulation of growth hormone secretion(GO:0060124)
0.0	0.0	GO:0030202	heparin metabolic process(GO:0030202)
0.0	0.1	GO:0006309	apoptotic DNA fragmentation(GO:0006309)
0.0	0.1	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0	0.0	GO:0035880	embryonic nail plate morphogenesis(GO:0035880)
0.0	0.0	GO:0003340	negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0003340)
0.0	0.0	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.0	0.1	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0	0.0	GO:1901727	positive regulation of histone deacetylase activity(GO:1901727)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:1901201	regulation of extracellular matrix assembly(GO:1901201)
0.0	0.0	GO:2000275	regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.0	0.1	GO:1901029	negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0	0.1	GO:0051882	mitochondrial depolarization(GO:0051882)
0.0	0.0	GO:0097475	motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476)
0.0	0.1	GO:0048935	peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0	0.0	GO:0071313	cellular response to caffeine(GO:0071313) cellular response to purine-containing compound(GO:0071415)
0.0	0.1	GO:0035729	response to hepatocyte growth factor(GO:0035728) cellular response to hepatocyte growth factor stimulus(GO:0035729)
0.0	0.1	GO:0090335	regulation of brown fat cell differentiation(GO:0090335)
0.0	0.0	GO:0046504	ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) cellular lipid biosynthetic process(GO:0097384) ether biosynthetic process(GO:1901503)
0.0	0.0	GO:0090272	negative regulation of fibroblast growth factor production(GO:0090272)
0.0	0.1	GO:0019852	L-ascorbic acid metabolic process(GO:0019852)
0.0	0.2	GO:0032008	positive regulation of TOR signaling(GO:0032008)
0.0	0.2	GO:0014733	regulation of skeletal muscle adaptation(GO:0014733)
0.0	0.0	GO:1900108	negative regulation of nodal signaling pathway(GO:1900108)
0.0	0.0	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.1	GO:0034141	positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0	0.0	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0	0.0	GO:0060166	olfactory pit development(GO:0060166)
0.0	0.1	GO:0071763	nuclear membrane organization(GO:0071763)
0.0	0.0	GO:0034454	microtubule anchoring at centrosome(GO:0034454)
0.0	0.0	GO:0032287	peripheral nervous system myelin maintenance(GO:0032287)
0.0	0.1	GO:0042637	catagen(GO:0042637)
0.0	0.2	GO:0035335	peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0	0.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.0	GO:1901896	positive regulation of calcium-transporting ATPase activity(GO:1901896)
0.0	0.0	GO:0002034	regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0	0.0	GO:0000733	DNA strand renaturation(GO:0000733)
0.0	0.0	GO:1900020	regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0	0.0	GO:2000009	negative regulation of protein localization to cell surface(GO:2000009)
0.0	0.0	GO:0070475	rRNA base methylation(GO:0070475)
0.0	0.0	GO:1900620	acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.0	0.1	GO:0010603	regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0	0.5	GO:0007040	lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.1	GO:1900029	positive regulation of ruffle assembly(GO:1900029)
0.0	0.0	GO:2000319	regulation of T-helper 17 cell differentiation(GO:2000319)
0.0	0.0	GO:0007258	JUN phosphorylation(GO:0007258)
0.0	0.0	GO:1903598	positive regulation of gap junction assembly(GO:1903598)
0.0	0.0	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.1	GO:0044829	positive regulation by host of viral genome replication(GO:0044829)
0.0	0.1	GO:0000083	regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0	0.1	GO:0006265	DNA topological change(GO:0006265)
0.0	0.1	GO:0030644	cellular chloride ion homeostasis(GO:0030644)
0.0	0.1	GO:0006528	asparagine metabolic process(GO:0006528)
0.0	0.1	GO:0042023	negative regulation of DNA endoreduplication(GO:0032876) DNA endoreduplication(GO:0042023)
0.0	0.0	GO:0045743	positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0	0.1	GO:0009133	nucleoside diphosphate biosynthetic process(GO:0009133)
0.0	0.1	GO:0007603	phototransduction, visible light(GO:0007603)
0.0	0.2	GO:0060337	type I interferon signaling pathway(GO:0060337) cellular response to type I interferon(GO:0071357)
0.0	0.0	GO:0015889	cobalamin transport(GO:0015889)
0.0	0.3	GO:0003333	amino acid transmembrane transport(GO:0003333)
0.0	0.4	GO:0030490	maturation of SSU-rRNA(GO:0030490)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:0018230	peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0	0.0	GO:0000965	mitochondrial RNA 3'-end processing(GO:0000965)
0.0	0.1	GO:0030575	nuclear body organization(GO:0030575)
0.0	0.1	GO:0006590	thyroid hormone generation(GO:0006590)
0.0	0.1	GO:0018298	protein-chromophore linkage(GO:0018298)
0.0	0.1	GO:0035855	megakaryocyte development(GO:0035855)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531) nucleotide transmembrane transport(GO:1901679)
0.0	0.0	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.0	GO:0048733	sebaceous gland development(GO:0048733)
0.0	0.0	GO:0061197	fungiform papilla morphogenesis(GO:0061197)
0.0	0.0	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.0	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.0	GO:0061643	chemorepulsion of axon(GO:0061643)
0.0	0.0	GO:0035021	negative regulation of Rac protein signal transduction(GO:0035021)
0.0	0.1	GO:0006264	mitochondrial DNA replication(GO:0006264)
0.0	0.0	GO:0061355	Wnt protein secretion(GO:0061355) regulation of Wnt protein secretion(GO:0061356)
0.0	0.0	GO:0019482	beta-alanine metabolic process(GO:0019482)
0.0	0.1	GO:0070935	3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0	0.1	GO:0042535	positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0	0.0	GO:0048014	Tie signaling pathway(GO:0048014)
0.0	0.2	GO:0030865	cortical cytoskeleton organization(GO:0030865)
0.0	0.0	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0	0.0	GO:0045586	regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.6	GO:0071141	SMAD protein complex(GO:0071141)
0.1	0.4	GO:0097629	extrinsic component of omegasome membrane(GO:0097629)
0.1	0.4	GO:0032127	dense core granule membrane(GO:0032127)
0.1	0.4	GO:0005899	insulin receptor complex(GO:0005899)
0.1	0.8	GO:0032009	early phagosome(GO:0032009)
0.1	0.6	GO:0020005	symbiont-containing vacuole membrane(GO:0020005)
0.1	0.4	GO:1990712	HFE-transferrin receptor complex(GO:1990712)
0.1	0.4	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1	0.3	GO:1990851	Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.1	0.6	GO:0033179	proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.1	1.1	GO:0031091	platelet alpha granule(GO:0031091)
0.1	0.3	GO:0000322	storage vacuole(GO:0000322)
0.1	0.2	GO:0000172	ribonuclease MRP complex(GO:0000172)
0.1	0.1	GO:0034679	integrin alpha9-beta1 complex(GO:0034679)
0.1	0.2	GO:0008282	ATP-sensitive potassium channel complex(GO:0008282)
0.1	0.2	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.1	GO:0031523	Myb complex(GO:0031523)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.2	GO:0000125	PCAF complex(GO:0000125)
0.0	0.1	GO:0032010	phagolysosome(GO:0032010)
0.0	0.2	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.2	GO:0071986	Ragulator complex(GO:0071986)
0.0	0.5	GO:0097431	mitotic spindle pole(GO:0097431)
0.0	0.3	GO:0043203	axon hillock(GO:0043203)
0.0	0.2	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.2	GO:0098651	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.3	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0020018	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.4	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.7	GO:0005782	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.1	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0008091	spectrin(GO:0008091)
0.0	0.4	GO:0012510	trans-Golgi network transport vesicle membrane(GO:0012510)
0.0	0.6	GO:0016327	apicolateral plasma membrane(GO:0016327)
0.0	0.2	GO:0070761	pre-snoRNP complex(GO:0070761)
0.0	0.1	GO:0071797	LUBAC complex(GO:0071797)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.4	GO:0016514	SWI/SNF complex(GO:0016514)
0.0	0.1	GO:0031262	Ndc80 complex(GO:0031262)
0.0	0.1	GO:0042585	germinal vesicle(GO:0042585)
0.0	0.1	GO:0044308	axonal spine(GO:0044308)
0.0	0.1	GO:1990635	proximal dendrite(GO:1990635)
0.0	0.3	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.1	GO:0000138	Golgi trans cisterna(GO:0000138)
0.0	0.1	GO:0000931	gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0	0.1	GO:0071547	piP-body(GO:0071547)
0.0	0.1	GO:0031417	NatC complex(GO:0031417)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.2	GO:0030314	junctional membrane complex(GO:0030314)
0.0	0.1	GO:0043219	lateral loop(GO:0043219)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.2	GO:0031254	uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.2	GO:0031932	TORC2 complex(GO:0031932)
0.0	0.1	GO:0097422	tubular endosome(GO:0097422)
0.0	0.3	GO:0000159	protein phosphatase type 2A complex(GO:0000159)
0.0	0.1	GO:0016471	vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0	0.1	GO:0030688	preribosome, small subunit precursor(GO:0030688)
0.0	0.1	GO:0016461	unconventional myosin complex(GO:0016461)
0.0	0.1	GO:0030128	clathrin coat of endocytic vesicle(GO:0030128)
0.0	0.1	GO:0097443	sorting endosome(GO:0097443)
0.0	0.2	GO:0000815	ESCRT III complex(GO:0000815)
0.0	0.1	GO:0031466	Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0	0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.0	0.2	GO:0042582	primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.1	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	0.1	GO:0061574	ASAP complex(GO:0061574)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0005688	U6 snRNP(GO:0005688)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0005833	hemoglobin complex(GO:0005833)
0.0	0.0	GO:0044194	cytolytic granule(GO:0044194)
0.0	0.0	GO:0097648	G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:0031209	SCAR complex(GO:0031209)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.3	GO:0080008	Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0	0.2	GO:0044292	dendrite terminus(GO:0044292)
0.0	0.2	GO:0030131	clathrin adaptor complex(GO:0030131)
0.0	0.1	GO:0042382	paraspeckles(GO:0042382)
0.0	1.0	GO:0005581	collagen trimer(GO:0005581)
0.0	0.0	GO:0005850	eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0	0.0	GO:0005879	axonemal microtubule(GO:0005879)
0.0	0.0	GO:0097512	cardiac myofibril(GO:0097512)
0.0	0.1	GO:0048237	rough endoplasmic reticulum lumen(GO:0048237)
0.0	0.0	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.0	GO:0032299	ribonuclease H2 complex(GO:0032299)
0.0	0.0	GO:0005967	mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0	0.1	GO:0031235	intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0	0.1	GO:0045239	tricarboxylic acid cycle enzyme complex(GO:0045239)
0.0	0.1	GO:0042105	alpha-beta T cell receptor complex(GO:0042105)
0.0	0.0	GO:0034457	Mpp10 complex(GO:0034457)
0.0	0.1	GO:0036157	outer dynein arm(GO:0036157)
0.0	0.0	GO:0048787	presynaptic active zone membrane(GO:0048787)
0.0	0.2	GO:0000777	condensed chromosome kinetochore(GO:0000777)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0071006	U2-type catalytic step 1 spliceosome(GO:0071006)
0.0	0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.0	0.0	GO:0036194	muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0	0.1	GO:1990111	spermatoproteasome complex(GO:1990111)
0.0	0.1	GO:0000800	lateral element(GO:0000800)
0.0	0.1	GO:0070652	HAUS complex(GO:0070652)
0.0	0.0	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.2	GO:0005666	DNA-directed RNA polymerase III complex(GO:0005666)
0.0	0.1	GO:0017146	NMDA selective glutamate receptor complex(GO:0017146)
0.0	0.0	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.0	GO:0033185	dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0005638	lamin filament(GO:0005638)
0.0	0.0	GO:0000814	ESCRT II complex(GO:0000814)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.5	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2	0.5	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.2	0.5	GO:0046976	histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2	0.5	GO:0071535	RING-like zinc finger domain binding(GO:0071535)
0.1	0.8	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.1	0.6	GO:0000064	L-ornithine transmembrane transporter activity(GO:0000064)
0.1	0.4	GO:0002060	purine nucleobase binding(GO:0002060)
0.1	0.3	GO:0043423	3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1	0.3	GO:0001069	regulatory region RNA binding(GO:0001069)
0.1	0.2	GO:0004065	arylsulfatase activity(GO:0004065)
0.1	0.3	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1	0.3	GO:0015182	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.4	GO:0004459	L-lactate dehydrogenase activity(GO:0004459)
0.1	0.2	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1	0.2	GO:0004103	choline kinase activity(GO:0004103)
0.1	0.8	GO:0010314	phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1	0.3	GO:0009374	biotin binding(GO:0009374)
0.1	0.3	GO:0022833	mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1	0.2	GO:0000171	ribonuclease MRP activity(GO:0000171)
0.1	0.2	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1	0.2	GO:0052795	exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1	0.2	GO:0004062	aryl sulfotransferase activity(GO:0004062)
0.1	0.3	GO:0051185	coenzyme transporter activity(GO:0051185)
0.1	0.1	GO:0030523	dihydrolipoamide S-acyltransferase activity(GO:0030523)
0.1	0.4	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.1	0.9	GO:0031690	adrenergic receptor binding(GO:0031690)
0.1	0.7	GO:0017166	vinculin binding(GO:0017166)
0.1	0.2	GO:0005128	erythropoietin receptor binding(GO:0005128)
0.1	0.1	GO:0043849	Ras palmitoyltransferase activity(GO:0043849)
0.1	0.2	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1	0.2	GO:0015563	uptake transmembrane transporter activity(GO:0015563)
0.0	0.1	GO:0090482	vitamin transmembrane transporter activity(GO:0090482)
0.0	0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.0	0.2	GO:0034889	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0	0.2	GO:0001515	opioid peptide activity(GO:0001515)
0.0	0.4	GO:0031702	type 1 angiotensin receptor binding(GO:0031702)
0.0	0.2	GO:0015232	heme transporter activity(GO:0015232)
0.0	0.9	GO:0005537	mannose binding(GO:0005537)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0035373	chondroitin sulfate proteoglycan binding(GO:0035373)
0.0	0.4	GO:0034841	3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.0	0.2	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.3	GO:0030346	protein phosphatase 2B binding(GO:0030346)
0.0	0.1	GO:0032050	clathrin heavy chain binding(GO:0032050)
0.0	0.4	GO:0051400	BH domain binding(GO:0051400)
0.0	0.1	GO:0000309	nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0	0.2	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0045504	dynein heavy chain binding(GO:0045504)
0.0	0.2	GO:0009378	four-way junction helicase activity(GO:0009378)
0.0	0.1	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.7	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.1	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.0	0.6	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.3	GO:0005041	low-density lipoprotein receptor activity(GO:0005041)
0.0	0.1	GO:0030984	kininogen binding(GO:0030984)
0.0	0.9	GO:0017112	Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0	0.3	GO:0050308	sugar-phosphatase activity(GO:0050308)
0.0	0.2	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0051864	histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0	0.1	GO:0097642	calcitonin family receptor activity(GO:0097642)
0.0	0.1	GO:0015154	sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0	0.1	GO:1990715	mRNA CDS binding(GO:1990715)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.3	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0	0.1	GO:0016312	inositol bisphosphate phosphatase activity(GO:0016312)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0005345	purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0	0.4	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0003847	1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0	1.0	GO:0001105	RNA polymerase II transcription coactivator activity(GO:0001105)
0.0	0.1	GO:0004563	beta-N-acetylhexosaminidase activity(GO:0004563)
0.0	0.2	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.1	GO:0071558	histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0	0.1	GO:0035184	histone threonine kinase activity(GO:0035184)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	2.0	GO:0005088	Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0	0.1	GO:0004523	RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.1	GO:0016822	hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0	0.1	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.3	GO:0005545	1-phosphatidylinositol binding(GO:0005545)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0004517	nitric-oxide synthase activity(GO:0004517)
0.0	0.1	GO:0005094	Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.2	GO:0015197	peptide transporter activity(GO:0015197)
0.0	0.5	GO:0019200	carbohydrate kinase activity(GO:0019200)
0.0	0.1	GO:0032896	palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0	0.2	GO:0001094	TFIID-class transcription factor binding(GO:0001094)
0.0	0.1	GO:0034452	dynactin binding(GO:0034452)
0.0	0.1	GO:0004995	tachykinin receptor activity(GO:0004995)
0.0	0.0	GO:0016415	octanoyltransferase activity(GO:0016415)
0.0	0.1	GO:0050816	phosphothreonine binding(GO:0050816)
0.0	0.1	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.1	GO:0016508	long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.1	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004957	prostaglandin E receptor activity(GO:0004957)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.8	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	0.1	GO:0008484	sulfuric ester hydrolase activity(GO:0008484)
0.0	0.2	GO:0016857	racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0	0.1	GO:0042609	CD4 receptor binding(GO:0042609)
0.0	0.1	GO:0016774	phosphotransferase activity, carboxyl group as acceptor(GO:0016774)
0.0	0.1	GO:0032767	copper-dependent protein binding(GO:0032767)
0.0	0.2	GO:0008331	high voltage-gated calcium channel activity(GO:0008331)
0.0	0.0	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.0	0.1	GO:0004985	opioid receptor activity(GO:0004985)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.2	GO:0004185	serine-type carboxypeptidase activity(GO:0004185)
0.0	0.1	GO:1990380	Lys48-specific deubiquitinase activity(GO:1990380)
0.0	0.0	GO:0004969	histamine receptor activity(GO:0004969)
0.0	0.2	GO:0038036	sphingosine-1-phosphate receptor activity(GO:0038036)
0.0	0.2	GO:0008599	protein phosphatase type 1 regulator activity(GO:0008599)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.2	GO:0032041	histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.1	GO:0031720	haptoglobin binding(GO:0031720)
0.0	0.2	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0004668	protein-arginine deiminase activity(GO:0004668)
0.0	0.1	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.2	GO:0031681	G-protein beta-subunit binding(GO:0031681)
0.0	0.1	GO:0016842	amidine-lyase activity(GO:0016842)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.0	GO:0052827	inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.2	GO:0008568	microtubule-severing ATPase activity(GO:0008568)
0.0	0.1	GO:0003958	NADPH-hemoprotein reductase activity(GO:0003958)
0.0	0.2	GO:0015026	coreceptor activity(GO:0015026)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.1	GO:0022858	L-alanine transmembrane transporter activity(GO:0015180) alanine transmembrane transporter activity(GO:0022858)
0.0	0.2	GO:0004806	triglyceride lipase activity(GO:0004806)
0.0	0.2	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.0	0.0	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.2	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0003918	DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0	0.0	GO:0004802	transketolase activity(GO:0004802)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:0019770	IgG receptor activity(GO:0019770)
0.0	0.1	GO:0004972	NMDA glutamate receptor activity(GO:0004972)
0.0	0.1	GO:0046790	virion binding(GO:0046790)
0.0	0.0	GO:0004705	JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0	0.2	GO:0036312	phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0	0.1	GO:0016174	NAD(P)H oxidase activity(GO:0016174)
0.0	0.0	GO:0046923	ER retention sequence binding(GO:0046923)
0.0	0.2	GO:0008553	hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0	0.3	GO:0005540	hyaluronic acid binding(GO:0005540)
0.0	0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0	0.2	GO:0004707	MAP kinase activity(GO:0004707)
0.0	0.1	GO:0015379	potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0	0.1	GO:0004566	beta-glucuronidase activity(GO:0004566)
0.0	0.1	GO:0004045	aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0	0.0	GO:0002046	opsin binding(GO:0002046)
0.0	0.2	GO:0043024	ribosomal small subunit binding(GO:0043024)
0.0	0.0	GO:0070653	high-density lipoprotein particle receptor binding(GO:0070653)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.0	GO:0003986	acetyl-CoA hydrolase activity(GO:0003986)
0.0	0.1	GO:0050656	3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.0	0.1	GO:0034584	piRNA binding(GO:0034584)
0.0	0.0	GO:0044213	intronic transcription regulatory region DNA binding(GO:0044213)
0.0	0.1	GO:0016443	bidentate ribonuclease III activity(GO:0016443)
0.0	0.1	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	0.2	GO:0016780	phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0	0.2	GO:0005048	signal sequence binding(GO:0005048)
0.0	0.1	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.5	GO:0033549	MAP kinase phosphatase activity(GO:0033549)
0.0	0.5	GO:0016406	carnitine O-acyltransferase activity(GO:0016406)
0.0	0.0	GO:0035514	DNA demethylase activity(GO:0035514)
0.0	0.1	GO:0036033	mediator complex binding(GO:0036033)
0.0	0.1	GO:0036122	BMP binding(GO:0036122)
0.0	0.0	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.0	0.0	GO:0019198	transmembrane receptor protein phosphatase activity(GO:0019198)
0.0	0.1	GO:0034916	4-methyloctanoyl-CoA dehydrogenase activity(GO:0034580) naphthyl-2-methyl-succinyl-CoA dehydrogenase activity(GO:0034845) 2-methylhexanoyl-CoA dehydrogenase activity(GO:0034916) propionyl-CoA dehydrogenase activity(GO:0043820) thiol-driven fumarate reductase activity(GO:0043830) coenzyme F420-dependent 2,4,6-trinitrophenol reductase activity(GO:0052758) coenzyme F420-dependent 2,4,6-trinitrophenol hydride reductase activity(GO:0052759) coenzyme F420-dependent 2,4-dinitrophenol reductase activity(GO:0052760)
0.0	0.1	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.2	GO:0001972	retinoic acid binding(GO:0001972)
0.0	0.0	GO:1901702	urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0	0.0	GO:0004965	G-protein coupled GABA receptor activity(GO:0004965)
0.0	0.0	GO:0004774	succinate-CoA ligase activity(GO:0004774)
0.0	0.0	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.2	GO:0004709	MAP kinase kinase kinase activity(GO:0004709)
0.0	0.2	GO:0005242	inward rectifier potassium channel activity(GO:0005242)
0.0	0.0	GO:0019788	NEDD8 transferase activity(GO:0019788)
0.0	0.0	GO:0042030	ATPase inhibitor activity(GO:0042030)
0.0	0.4	GO:0016831	carboxy-lyase activity(GO:0016831)
0.0	0.1	GO:0070410	co-SMAD binding(GO:0070410)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)
0.0	0.3	GO:0004864	protein phosphatase inhibitor activity(GO:0004864)
0.0	0.1	GO:0005313	L-glutamate transmembrane transporter activity(GO:0005313)
0.0	0.1	GO:0019957	C-C chemokine binding(GO:0019957)
0.0	0.0	GO:0070815	peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0	0.0	GO:0031711	bradykinin receptor binding(GO:0031711)
0.0	0.3	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0	0.1	GO:1990405	protein antigen binding(GO:1990405)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:1990239	steroid hormone binding(GO:1990239)
0.0	0.3	GO:0017147	Wnt-protein binding(GO:0017147)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.0	GO:0015526	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.0	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.0	GO:0030911	TPR domain binding(GO:0030911)
0.0	0.1	GO:0031545	peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.0	0.2	GO:0004521	endoribonuclease activity(GO:0004521)
0.0	0.1	GO:0035497	cAMP response element binding(GO:0035497)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	ST INTEGRIN SIGNALING PATHWAY	Integrin Signaling Pathway
1.2	PID CDC42 REG PATHWAY	Regulation of CDC42 activity
0.8	PID RAC1 REG PATHWAY	Regulation of RAC1 activity
0.5	PID SMAD2 3PATHWAY	Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.6	PID INTEGRIN2 PATHWAY	Beta2 integrin cell surface interactions
0.2	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.1	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.7	ST T CELL SIGNAL TRANSDUCTION	T Cell Signal Transduction
0.1	PID IL5 PATHWAY	IL5-mediated signaling events
0.5	PID INTEGRIN A9B1 PATHWAY	Alpha9 beta1 integrin signaling events
0.0	PID NFKAPPAB CANONICAL PATHWAY	Canonical NF-kappaB pathway
0.2	PID IL2 PI3K PATHWAY	IL2 signaling events mediated by PI3K
0.2	PID KIT PATHWAY	Signaling events mediated by Stem cell factor receptor (c-Kit)
0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.6	PID AR TF PATHWAY	Regulation of Androgen receptor activity
0.2	PID S1P S1P1 PATHWAY	S1P1 pathway
0.2	PID THROMBIN PAR4 PATHWAY	PAR4-mediated thrombin signaling events
0.9	PID HIF1 TFPATHWAY	HIF-1-alpha transcription factor network
0.4	PID SYNDECAN 4 PATHWAY	Syndecan-4-mediated signaling events
0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway
0.0	PID CD40 PATHWAY	CD40/CD40L signaling
0.2	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.4	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.4	PID P38 ALPHA BETA PATHWAY	Regulation of p38-alpha and p38-beta
0.2	PID AVB3 OPN PATHWAY	Osteopontin-mediated events
0.4	PID ATM PATHWAY	ATM pathway
0.1	PID TRAIL PATHWAY	TRAIL signaling pathway
0.1	PID ANGIOPOIETIN RECEPTOR PATHWAY	Angiopoietin receptor Tie2-mediated signaling
0.1	ST INTERLEUKIN 4 PATHWAY	Interleukin 4 (IL-4) Pathway
0.0	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.2	PID ARF 3PATHWAY	Arf1 pathway
0.4	PID INSULIN PATHWAY	Insulin Pathway
0.2	PID INTEGRIN CS PATHWAY	Integrin family cell surface interactions
0.3	PID IL2 STAT5 PATHWAY	IL2 signaling events mediated by STAT5
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.3	PID FRA PATHWAY	Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0	SIG IL4RECEPTOR IN B LYPHOCYTES	Genes related to IL4 rceptor signaling in B lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.5	REACTOME KERATAN SULFATE DEGRADATION	Genes involved in Keratan sulfate degradation
0.0	REACTOME SPRY REGULATION OF FGF SIGNALING	Genes involved in Spry regulation of FGF signaling
1.0	REACTOME INSULIN RECEPTOR RECYCLING	Genes involved in Insulin receptor recycling
0.3	REACTOME INTEGRATION OF ENERGY METABOLISM	Genes involved in Integration of energy metabolism
0.6	REACTOME DCC MEDIATED ATTRACTIVE SIGNALING	Genes involved in DCC mediated attractive signaling
0.0	REACTOME DESTABILIZATION OF MRNA BY BRF1	Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0	REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS	Genes involved in Interactions of Vpr with host cellular proteins
0.4	REACTOME GAP JUNCTION DEGRADATION	Genes involved in Gap junction degradation
0.0	REACTOME CTLA4 INHIBITORY SIGNALING	Genes involved in CTLA4 inhibitory signaling
0.3	REACTOME THE ACTIVATION OF ARYLSULFATASES	Genes involved in The activation of arylsulfatases
0.1	REACTOME OLFACTORY SIGNALING PATHWAY	Genes involved in Olfactory Signaling Pathway
0.5	REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS	Genes involved in Cell-extracellular matrix interactions
0.3	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.6	REACTOME SIGNALING BY NODAL	Genes involved in Signaling by NODAL
0.4	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.4	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.4	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.9	REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE	Genes involved in Amino acid transport across the plasma membrane
0.2	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.6	REACTOME METAL ION SLC TRANSPORTERS	Genes involved in Metal ion SLC transporters
0.6	REACTOME RNA POL I TRANSCRIPTION INITIATION	Genes involved in RNA Polymerase I Transcription Initiation
0.2	REACTOME HYALURONAN UPTAKE AND DEGRADATION	Genes involved in Hyaluronan uptake and degradation
0.3	REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE	Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.4	REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM	Genes involved in Branched-chain amino acid catabolism
0.3	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.2	REACTOME NOTCH HLH TRANSCRIPTION PATHWAY	Genes involved in Notch-HLH transcription pathway
0.4	REACTOME CITRIC ACID CYCLE TCA CYCLE	Genes involved in Citric acid cycle (TCA cycle)
0.1	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.1	REACTOME PECAM1 INTERACTIONS	Genes involved in PECAM1 interactions
0.2	REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES	Genes involved in Recruitment of NuMA to mitotic centrosomes
0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.2	REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS	Genes involved in Trafficking of GluR2-containing AMPA receptors
0.2	REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION	Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1	REACTOME HYALURONAN METABOLISM	Genes involved in Hyaluronan metabolism
0.1	REACTOME REGULATION OF IFNA SIGNALING	Genes involved in Regulation of IFNA signaling
0.4	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.5	REACTOME INWARDLY RECTIFYING K CHANNELS	Genes involved in Inwardly rectifying K+ channels
0.2	REACTOME PRE NOTCH PROCESSING IN GOLGI	Genes involved in Pre-NOTCH Processing in Golgi
0.2	REACTOME ACTIVATION OF RAC	Genes involved in Activation of Rac
0.0	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.1	REACTOME DOWNSTREAM SIGNALING EVENTS OF B CELL RECEPTOR BCR	Genes involved in Downstream Signaling Events Of B Cell Receptor (BCR)
0.0	REACTOME FGFR4 LIGAND BINDING AND ACTIVATION	Genes involved in FGFR4 ligand binding and activation
0.0	REACTOME DAG AND IP3 SIGNALING	Genes involved in DAG and IP3 signaling
0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.2	REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION	Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.3	REACTOME G0 AND EARLY G1	Genes involved in G0 and Early G1
0.2	REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS	Genes involved in Facilitative Na+-independent glucose transporters
0.2	REACTOME PYRUVATE METABOLISM	Genes involved in Pyruvate metabolism
0.2	REACTOME IL 7 SIGNALING	Genes involved in Interleukin-7 signaling
0.1	REACTOME SIGNALING BY SCF KIT	Genes involved in Signaling by SCF-KIT
0.1	REACTOME NEPHRIN INTERACTIONS	Genes involved in Nephrin interactions
0.1	REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1	REACTOME RAF MAP KINASE CASCADE	Genes involved in RAF/MAP kinase cascade
0.5	REACTOME NRAGE SIGNALS DEATH THROUGH JNK	Genes involved in NRAGE signals death through JNK
0.0	REACTOME PYRUVATE METABOLISM AND CITRIC ACID TCA CYCLE	Genes involved in Pyruvate metabolism and Citric Acid (TCA) cycle
0.1	REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE	Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1	REACTOME REGULATION OF COMPLEMENT CASCADE	Genes involved in Regulation of Complement cascade
0.2	REACTOME GPVI MEDIATED ACTIVATION CASCADE	Genes involved in GPVI-mediated activation cascade
0.0	REACTOME REGULATED PROTEOLYSIS OF P75NTR	Genes involved in Regulated proteolysis of p75NTR
0.2	REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION	Genes involved in Amino acid synthesis and interconversion (transamination)
0.1	REACTOME SIGNALING BY FGFR1 FUSION MUTANTS	Genes involved in Signaling by FGFR1 fusion mutants
0.0	REACTOME PD1 SIGNALING	Genes involved in PD-1 signaling
0.1	REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX	Genes involved in Association of licensing factors with the pre-replicative complex
0.1	REACTOME GLUCURONIDATION	Genes involved in Glucuronidation
0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.2	REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE	Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.3	REACTOME INTERFERON GAMMA SIGNALING	Genes involved in Interferon gamma signaling
0.1	REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS	Genes involved in Na+/Cl- dependent neurotransmitter transporters

Results for Tfap4

Z-value: 3.05

Motif logo

Transcription factors associated with Tfap4

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tfap4 motif across conditions

Conditions sorted by the z-value of the Tfap4 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap4

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: