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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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Results for Tfcp2

Z-value: 0.88

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Transcription factors associated with Tfcp2

Gene Symbol	Gene ID	Gene Info
Tfcp2 Ensembl NCBI MGI UniProt	ENSMUSG00000009733.8	transcription factor CP2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE	Gene	Distance	Association probability	Pearson corr. coef.	P-value	Plot
chr15_100537987_100538140	Tfcp2	12330	0.108936	-0.79	5.9e-02	Click!
chr15_100551769_100552156	Tfcp2	19	0.959085	0.54	2.7e-01	Click!
chr15_100551472_100551651	Tfcp2	10	0.959615	-0.05	9.3e-01	Click!
chr15_100552258_100552413	Tfcp2	327	0.808787	-0.03	9.5e-01	Click!

Activity of the Tfcp2 motif across conditions

Conditions sorted by the z-value of the Tfcp2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr14_16530464_16530632	0.44	Rarb	retinoic acid receptor, beta	44497	0.15
chr19_43971247_43971535	0.42	Cpn1	carboxypeptidase N, polypeptide 1	2698	0.21
chr15_68255673_68255836	0.42	Zfat	zinc finger and AT hook domain containing	3033	0.26
chr6_128504140_128504367	0.41	Pzp	PZP, alpha-2-macroglobulin like	9030	0.09
chr6_51392183_51392564	0.40	0610033M10Rik	RIKEN cDNA 0610033M10 gene	9660	0.17
chr2_76639734_76639916	0.39	Prkra	protein kinase, interferon inducible double stranded RNA dependent activator	908	0.53
chr4_117342819_117343008	0.37	Rnf220	ring finger protein 220	32544	0.12
chr5_120514188_120514356	0.35	Slc8b1	solute carrier family 8 (sodium/lithium/calcium exchanger), member B1	1129	0.34
chr17_27557519_27557704	0.35	Hmga1	high mobility group AT-hook 1	916	0.28
chr10_95878338_95878489	0.34	Gm47724	predicted gene, 47724	7614	0.13
chr6_54759739_54759890	0.33	Znrf2	zinc and ring finger 2	57102	0.1
chr14_30890557_30890708	0.32	Itih4	inter alpha-trypsin inhibitor, heavy chain 4	4111	0.13
chr5_8977445_8977723	0.31	Crot	carnitine O-octanoyltransferase	4560	0.14
chr5_88918674_88918881	0.30	Slc4a4	solute carrier family 4 (anion exchanger), member 4	15755	0.23
chr7_141171399_141171582	0.30	Rnh1	ribonuclease/angiogenin inhibitor 1	1367	0.2
chr17_3989752_3989920	0.30	4930470H14Rik	RIKEN cDNA 4930470H14 gene	93159	0.09
chr1_64791801_64792159	0.29	Plekhm3	pleckstrin homology domain containing, family M, member 3	44784	0.11
chr4_60659551_60660018	0.29	Mup11	major urinary protein 11	46	0.97
chr8_94172420_94173095	0.28	Mt2	metallothionein 2	93	0.88
chr8_119425498_119425673	0.26	Osgin1	oxidative stress induced growth inhibitor 1	8539	0.15
chr4_15327477_15327645	0.26	Gm24317	predicted gene, 24317	55587	0.13
chr10_13869659_13869820	0.26	Aig1	androgen-induced 1	759	0.5
chr5_145873496_145873886	0.26	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	3000	0.22
chr12_21183631_21184095	0.26	AC156032.1		63460	0.08
chr2_72881753_72881905	0.25	Sp3	trans-acting transcription factor 3	59255	0.1
chr12_79140897_79141048	0.25	Arg2	arginase type II	10195	0.09
chr4_35134107_35134262	0.25	Ifnk	interferon kappa	17872	0.17
chr6_91111481_91112156	0.25	Nup210	nucleoporin 210	4978	0.17
chr1_165766009_165766175	0.25	Creg1	cellular repressor of E1A-stimulated genes 1	2346	0.15
chr7_27542323_27542474	0.24	Pld3	phospholipase D family, member 3	347	0.77
chr4_57312348_57312552	0.24	Ptpn3	protein tyrosine phosphatase, non-receptor type 3	10613	0.17
chr6_94357642_94357793	0.23	Gm19908	predicted gene, 19908	8183	0.21
chr9_70913787_70914085	0.23	Gm32017	predicted gene, 32017	16552	0.19
chr12_101766669_101766841	0.23	Tc2n	tandem C2 domains, nuclear	48232	0.12
chr1_67194458_67194637	0.23	Gm15668	predicted gene 15668	54653	0.12
chr11_101377034_101377689	0.23	G6pc	glucose-6-phosphatase, catalytic	9800	0.06
chr9_108785280_108785665	0.23	Ip6k2	inositol hexaphosphate kinase 2	1607	0.21
chr2_170287488_170287839	0.23	Gm14270	predicted gene 14270	2628	0.33
chr10_63160777_63160928	0.23	Mypn	myopalladin	38168	0.1
chr12_77216600_77216773	0.22	Fut8	fucosyltransferase 8	21439	0.19
chr1_16172552_16172725	0.22	Gm38249	predicted gene, 38249	37879	0.13
chr8_34434777_34434932	0.22	Gm45349	predicted gene 45349	38141	0.12
chr12_7987781_7988288	0.22	Apob	apolipoprotein B	10255	0.22
chr17_12415417_12415751	0.22	Plg	plasminogen	36925	0.12
chr10_93491843_93492023	0.22	Hal	histidine ammonia lyase	3130	0.19
chr1_105965333_105965503	0.22	Gm18801	predicted gene, 18801	9108	0.15
chr1_36573916_36574068	0.22	Fam178b	family with sequence similarity 178, member B	13695	0.09
chr4_60821413_60821822	0.21	Mup22	major urinary protein 22	154	0.96
chr10_7976561_7976927	0.21	Tab2	TGF-beta activated kinase 1/MAP3K7 binding protein 2	20514	0.19
chr15_99406396_99406547	0.21	Tmbim6	transmembrane BAX inhibitor motif containing 6	597	0.56
chr4_123576766_123577231	0.21	Macf1	microtubule-actin crosslinking factor 1	3938	0.22
chr14_41104159_41104453	0.21	Mat1a	methionine adenosyltransferase I, alpha	729	0.55
chr2_118534050_118534205	0.21	Bmf	BCL2 modifying factor	10460	0.16
chr7_68717199_68717404	0.21	Gm44692	predicted gene 44692	9166	0.23
chr15_86177362_86177531	0.21	Gm15569	predicted gene 15569	8282	0.17
chr18_53353090_53353276	0.20	Ppic	peptidylprolyl isomerase C	64932	0.12
chr5_90872752_90873224	0.20	Cxcl1	chemokine (C-X-C motif) ligand 1	18253	0.11
chr8_94186443_94186638	0.20	Gm39228	predicted gene, 39228	3251	0.13
chr13_37943133_37943379	0.20	Rreb1	ras responsive element binding protein 1	3760	0.25
chr16_22914452_22914638	0.20	Fetub	fetuin beta	3789	0.14
chr19_3958627_3958778	0.20	Aldh3b3	aldehyde dehydrogenase 3 family, member B3	57	0.92
chr13_30233563_30233739	0.20	Mboat1	membrane bound O-acyltransferase domain containing 1	1798	0.39
chr11_64844149_64844351	0.20	Gm12292	predicted gene 12292	497	0.87
chr5_117245335_117245486	0.20	Taok3	TAO kinase 3	4950	0.16
chr9_32718091_32718269	0.20	Gm27240	predicted gene 27240	7009	0.2
chr1_191225741_191225922	0.20	D730003I15Rik	RIKEN cDNA D730003I15 gene	1357	0.33
chr8_117718222_117718447	0.20	Hsd17b2	hydroxysteroid (17-beta) dehydrogenase 2	2602	0.2
chr14_100324093_100324244	0.20	Gm41231	predicted gene, 41231	38003	0.15
chr1_178330385_178330898	0.20	Hnrnpu	heterogeneous nuclear ribonucleoprotein U	20	0.96
chr10_93742676_93742904	0.20	Gm15963	predicted gene 15963	14583	0.15
chr7_44892625_44892974	0.20	Med25	mediator complex subunit 25	87	0.91
chr14_73445592_73445761	0.19	Gm4266	predicted gene 4266	47417	0.11
chr4_60741366_60741658	0.19	Mup12	major urinary protein 12	186	0.94
chr9_58085168_58085353	0.19	Ccdc33	coiled-coil domain containing 33	3191	0.18
chr9_78031227_78031411	0.19	Gm47829	predicted gene, 47829	3374	0.14
chr16_31493024_31493411	0.19	Gm46560	predicted gene, 46560	15170	0.14
chr10_24635350_24635521	0.19	Gm15270	predicted gene 15270	38327	0.13
chr8_33913458_33913624	0.19	Rbpms	RNA binding protein gene with multiple splicing	15735	0.16
chr4_145041587_145041938	0.19	Vps13d	vacuolar protein sorting 13D	9272	0.25
chr7_123193753_123193930	0.19	Tnrc6a	trinucleotide repeat containing 6a	13920	0.2
chr5_118246346_118246796	0.19	2410131K14Rik	RIKEN cDNA 2410131K14 gene	1344	0.32
chr11_107130421_107130628	0.19	Bptf	bromodomain PHD finger transcription factor	1398	0.36
chr11_115290095_115290276	0.19	Fads6	fatty acid desaturase domain family, member 6	7329	0.1
chr6_142752473_142752975	0.19	Cmas	cytidine monophospho-N-acetylneuraminic acid synthetase	3962	0.23
chr14_45457123_45457466	0.19	Gm34250	predicted gene, 34250	10221	0.12
chr13_52236242_52236425	0.19	Gm48199	predicted gene, 48199	55922	0.15
chr1_36527353_36527514	0.18	Gm38033	predicted gene, 38033	804	0.4
chr11_121082992_121083151	0.18	Sectm1a	secreted and transmembrane 1A	1851	0.17
chr1_184060517_184060686	0.18	Dusp10	dual specificity phosphatase 10	26220	0.19
chr5_102483486_102483664	0.18	1700013M08Rik	RIKEN cDNA 1700013M08 gene	286	0.9
chr3_98322281_98322464	0.18	Phgdh	3-phosphoglycerate dehydrogenase	6241	0.17
chr11_69110217_69110963	0.18	Hes7	hes family bHLH transcription factor 7	9814	0.07
chr15_89209095_89209277	0.18	Ppp6r2	protein phosphatase 6, regulatory subunit 2	2367	0.16
chr3_95668091_95668297	0.18	Adamtsl4	ADAMTS-like 4	8957	0.1
chr13_93648931_93649116	0.18	Bhmt	betaine-homocysteine methyltransferase	11062	0.14
chr5_32141078_32141248	0.18	Fosl2	fos-like antigen 2	4990	0.17
chr7_139247418_139247589	0.17	Pwwp2b	PWWP domain containing 2B	979	0.48
chr14_120318430_120318607	0.17	Mbnl2	muscleblind like splicing factor 2	12062	0.26
chr15_83704064_83704215	0.17	Scube1	signal peptide, CUB domain, EGF-like 1	20787	0.2
chr12_31295518_31295688	0.17	Lamb1	laminin B1	17428	0.13
chr10_77086952_77087277	0.17	Col18a1	collagen, type XVIII, alpha 1	2314	0.26
chr5_8940920_8941071	0.17	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	12269	0.13
chr11_94207284_94207435	0.17	Tob1	transducer of ErbB-2.1	4095	0.21
chr2_156451427_156451737	0.17	Gm14225	predicted gene 14225	3974	0.13
chr6_129434345_129434496	0.17	Gm43914	predicted gene, 43914	16241	0.09
chr2_158225371_158225751	0.17	D630003M21Rik	RIKEN cDNA D630003M21 gene	3661	0.17
chr17_83503490_83503653	0.17	Cox7a2l	cytochrome c oxidase subunit 7A2 like	935	0.66
chr6_128604604_128605019	0.17	Gm44009	predicted gene, 44009	16786	0.08
chr1_178230411_178230566	0.17	Desi2	desumoylating isopeptidase 2	25615	0.13
chr5_149247178_149247337	0.17	Gm29264	predicted gene 29264	425	0.57
chr1_132365008_132365179	0.17	Tmcc2	transmembrane and coiled-coil domains 2	145	0.93
chr9_57287321_57287487	0.17	1700017B05Rik	RIKEN cDNA 1700017B05 gene	24792	0.13
chr6_90621325_90621476	0.16	Slc41a3	solute carrier family 41, member 3	2253	0.23
chr6_72261113_72261288	0.16	Atoh8	atonal bHLH transcription factor 8	25623	0.12
chr18_34915325_34915481	0.16	Etf1	eukaryotic translation termination factor 1	16604	0.11
chr8_3252795_3252979	0.16	Gm16180	predicted gene 16180	6817	0.21
chr4_61883600_61883752	0.16	Mup-ps18	major urinary protein, pseudogene 18	380	0.82
chr9_109911713_109911882	0.16	Gm4644	predicted gene 4644	12953	0.11
chr13_40855241_40855443	0.16	Gcnt2	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme	4412	0.12
chr11_51640853_51641004	0.16	Rmnd5b	required for meiotic nuclear division 5 homolog B	5032	0.13
chr8_88118582_88118749	0.16	Cnep1r1	CTD nuclear envelope phosphatase 1 regulatory subunit 1	104	0.95
chr12_85451886_85452044	0.16	Gm40477	predicted gene, 40477	15716	0.14
chr11_81374622_81374773	0.16	4930527B05Rik	RIKEN cDNA 4930527B05 gene	10316	0.3
chr19_41326438_41326633	0.16	Pik3ap1	phosphoinositide-3-kinase adaptor protein 1	58561	0.12
chr9_119936578_119936796	0.16	Gorasp1	golgi reassembly stacking protein 1	863	0.34
chr6_95819185_95819380	0.16	Suclg2	succinate-Coenzyme A ligase, GDP-forming, beta subunit	100482	0.08
chr7_127804573_127804884	0.16	9430064I24Rik	RIKEN cDNA 9430064I24 gene	1966	0.13
chr3_27490084_27490238	0.16	Gm43344	predicted gene 43344	56480	0.14
chr4_123527493_123527861	0.16	Macf1	microtubule-actin crosslinking factor 1	29	0.98
chr2_33200439_33200604	0.16	Gm23546	predicted gene, 23546	11420	0.14
chr4_129641917_129642148	0.16	Txlna	taxilin alpha	967	0.34
chr14_34562012_34562194	0.16	Ldb3	LIM domain binding 3	14891	0.12
chr4_10926160_10926369	0.16	Rps11-ps3	ribosomal protein S11, pseudogene 3	20344	0.15
chr18_3010677_3010845	0.16	Gm50072	predicted gene, 50072	5147	0.22
chr1_39650381_39650532	0.16	D930019O06Rik	RIKEN cDNA D930019O06	280	0.82
chr10_122384642_122385270	0.16	Gm36041	predicted gene, 36041	1936	0.39
chr2_84386945_84387393	0.15	Calcrl	calcitonin receptor-like	11811	0.2
chr8_45626518_45626714	0.15	Sorbs2	sorbin and SH3 domain containing 2	1123	0.5
chr8_126869593_126869763	0.15	Gm31718	predicted gene, 31718	6760	0.2
chr17_31656771_31656922	0.15	U2af1	U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 1	356	0.77
chr8_126588770_126588952	0.15	Irf2bp2	interferon regulatory factor 2 binding protein 2	5125	0.24
chr16_91762844_91763094	0.15	Itsn1	intersectin 1 (SH3 domain protein 1A)	6870	0.17
chr1_133222741_133222940	0.15	Plekha6	pleckstrin homology domain containing, family A member 6	23257	0.15
chr9_43984454_43984635	0.15	Gm10688	predicted gene 10688	5067	0.11
chr5_123376677_123377005	0.15	5830487J09Rik	RIKEN cDNA 5830487J09 gene	9842	0.08
chr6_49166006_49166162	0.15	Gm18010	predicted gene, 18010	6675	0.17
chr19_20698070_20698334	0.15	Aldh1a7	aldehyde dehydrogenase family 1, subfamily A7	29360	0.21
chr5_89018649_89018800	0.15	Slc4a4	solute carrier family 4 (anion exchanger), member 4	9242	0.29
chr6_127254053_127254240	0.15	Gm43635	predicted gene 43635	498	0.71
chr4_61436878_61437320	0.15	Mup15	major urinary protein 15	2644	0.27
chr7_19956433_19956628	0.15	Rpl7a-ps8	ribosomal protein L7A, pseudogene 8	2747	0.12
chr8_123477065_123477339	0.15	Afg3l1	AFG3-like AAA ATPase 1	701	0.34
chr11_90252425_90252669	0.15	Mmd	monocyte to macrophage differentiation-associated	3071	0.29
chr11_108782497_108782676	0.15	Cep112	centrosomal protein 112	30381	0.16
chr4_61782137_61782580	0.15	Mup19	major urinary protein 19	89	0.91
chr19_38223407_38224029	0.15	Fra10ac1	FRA10AC1 homolog (human)	420	0.83
chr5_73544450_73544608	0.15	Dcun1d4	DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)	33661	0.14
chr5_89032794_89032952	0.15	Slc4a4	solute carrier family 4 (anion exchanger), member 4	4781	0.33
chr18_24652431_24652590	0.15	Mocos	molybdenum cofactor sulfurase	1181	0.43
chr16_28990306_28990479	0.15	Gm8253	predicted gene 8253	39037	0.19
chr13_101967419_101967852	0.15	Gm17832	predicted gene, 17832	47215	0.17
chr3_37747859_37748010	0.15	Gm42921	predicted gene 42921	13103	0.11
chr8_22505624_22505807	0.15	Slc20a2	solute carrier family 20, member 2	410	0.8
chr11_22276015_22276166	0.15	Ehbp1	EH domain binding protein 1	9748	0.28
chr6_59962335_59962486	0.15	Gm18012	predicted gene, 18012	20059	0.25
chr1_39869838_39870141	0.15	1700066B17Rik	RIKEN cDNA 1700066B17 gene	22655	0.18
chrX_134248838_134248996	0.15	Nox1	NADPH oxidase 1	26961	0.13
chr16_23135545_23135714	0.15	Gm49624	predicted gene, 49624	1309	0.19
chr11_7197846_7198073	0.14	Igfbp1	insulin-like growth factor binding protein 1	177	0.94
chr6_90336860_90337033	0.14	Uroc1	urocanase domain containing 1	3657	0.14
chr7_30640868_30641046	0.14	Rbm42	RNA binding motif protein 42	5030	0.07
chr3_83032786_83032957	0.14	Fga	fibrinogen alpha chain	6656	0.15
chr9_110702981_110703204	0.14	Ccdc12	coiled-coil domain containing 12	6802	0.12
chr5_114556398_114556701	0.14	Gm13790	predicted gene 13790	5260	0.18
chr6_31221431_31221835	0.14	Lncpint	long non-protein coding RNA, Trp53 induced transcript	1145	0.34
chr8_26982042_26982193	0.14	Gm45371	predicted gene 45371	2116	0.17
chr10_99384294_99384806	0.14	B530045E10Rik	RIKEN cDNA B530045E10 gene	18240	0.17
chr10_28648583_28648734	0.14	Themis	thymocyte selection associated	19702	0.24
chr10_117860469_117860663	0.14	Gm40773	predicted gene, 40773	4104	0.17
chr10_95548575_95548786	0.14	Ube2n	ubiquitin-conjugating enzyme E2N	7167	0.13
chr7_29231412_29231751	0.14	Kcnk6	potassium inwardly-rectifying channel, subfamily K, member 6	274	0.81
chr19_30092015_30092195	0.14	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	144	0.96
chr4_148728491_148728680	0.14	Gm13203	predicted gene 13203	14882	0.18
chr9_78030589_78030835	0.14	Gm47829	predicted gene, 47829	2767	0.16
chr17_73029242_73029393	0.14	Gm30420	predicted gene, 30420	239	0.94
chr13_92609818_92609992	0.14	Serinc5	serine incorporator 5	1186	0.52
chr1_183349812_183350128	0.14	Mia3	melanoma inhibitory activity 3	1138	0.4
chr11_100814569_100814933	0.14	Stat5b	signal transducer and activator of transcription 5B	7777	0.13
chr10_69154715_69154964	0.14	Rhobtb1	Rho-related BTB domain containing 1	3405	0.2
chr4_61593182_61593358	0.14	Mup17	major urinary protein 17	2601	0.25
chr2_179287187_179287374	0.14	Gm14293	predicted gene 14293	46790	0.16
chr9_46217190_46217346	0.14	Sik3	SIK family kinase 3	2303	0.16
chr15_83471603_83471756	0.14	Pacsin2	protein kinase C and casein kinase substrate in neurons 2	7073	0.15
chr12_80218314_80218489	0.14	Gm47767	predicted gene, 47767	9158	0.15
chr1_127014601_127014752	0.14	Gm5261	predicted gene 5261	36020	0.21
chr4_60419310_60419496	0.14	Mup9	major urinary protein 9	1181	0.4
chr9_110335063_110335244	0.14	Scap	SREBF chaperone	1517	0.26
chr2_167634687_167634863	0.14	Ube2v1	ubiquitin-conjugating enzyme E2 variant 1	2680	0.16
chr4_132655416_132655575	0.14	Eya3	EYA transcriptional coactivator and phosphatase 3	1205	0.44
chr8_41024281_41024448	0.14	Mtus1	mitochondrial tumor suppressor 1	1462	0.35

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:1990169	detoxification of copper ion(GO:0010273) stress response to copper ion(GO:1990169)
0.1	0.2	GO:1902730	regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.0	0.1	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.1	GO:0032074	negative regulation of nuclease activity(GO:0032074)
0.0	0.2	GO:0010940	positive regulation of necrotic cell death(GO:0010940)
0.0	0.1	GO:0006556	S-adenosylmethionine biosynthetic process(GO:0006556)
0.0	0.2	GO:0060397	JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0	0.1	GO:0015803	branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0	0.2	GO:0030422	production of siRNA involved in RNA interference(GO:0030422)
0.0	0.1	GO:0097296	activation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:0097296)
0.0	0.1	GO:0071879	positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.0	0.1	GO:0051791	medium-chain fatty acid metabolic process(GO:0051791)
0.0	0.2	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:0006435	threonyl-tRNA aminoacylation(GO:0006435)
0.0	0.1	GO:0019448	cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0	0.2	GO:0006620	posttranslational protein targeting to membrane(GO:0006620)
0.0	0.1	GO:0010735	positive regulation of transcription via serum response element binding(GO:0010735)
0.0	0.1	GO:1904220	regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0	0.1	GO:0010360	negative regulation of anion channel activity(GO:0010360)
0.0	0.1	GO:2001180	negative regulation of interleukin-10 secretion(GO:2001180)
0.0	0.1	GO:0060264	regulation of respiratory burst involved in inflammatory response(GO:0060264)
0.0	0.1	GO:0016479	negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.0	0.1	GO:0007171	activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0	0.1	GO:0006344	maintenance of chromatin silencing(GO:0006344)
0.0	0.1	GO:0018992	germ-line sex determination(GO:0018992)
0.0	0.2	GO:0006658	phosphatidylserine metabolic process(GO:0006658)
0.0	0.2	GO:1900028	negative regulation of ruffle assembly(GO:1900028)
0.0	0.1	GO:0018197	peptidyl-aspartic acid modification(GO:0018197)
0.0	0.2	GO:0010216	maintenance of DNA methylation(GO:0010216)
0.0	0.1	GO:0034093	positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.1	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.0	GO:0002430	complement receptor mediated signaling pathway(GO:0002430)
0.0	0.1	GO:0006546	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.0	0.1	GO:0003406	retinal pigment epithelium development(GO:0003406)
0.0	0.0	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.1	GO:0035790	platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.0	0.0	GO:0061687	detoxification of inorganic compound(GO:0061687)
0.0	0.1	GO:2000480	negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0	0.1	GO:0030242	pexophagy(GO:0030242)
0.0	0.1	GO:0051661	maintenance of centrosome location(GO:0051661)
0.0	0.1	GO:0051541	elastin metabolic process(GO:0051541)
0.0	0.1	GO:0035283	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.0	0.0	GO:1901382	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.1	GO:0042732	D-xylose metabolic process(GO:0042732)
0.0	0.0	GO:1990791	dorsal root ganglion development(GO:1990791)
0.0	0.1	GO:0098902	regulation of membrane depolarization during action potential(GO:0098902)
0.0	0.2	GO:0035563	positive regulation of chromatin binding(GO:0035563)
0.0	0.1	GO:0045041	protein import into mitochondrial intermembrane space(GO:0045041)
0.0	0.1	GO:0035973	aggrephagy(GO:0035973)
0.0	0.1	GO:0052422	modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0	0.1	GO:0001543	ovarian follicle rupture(GO:0001543)
0.0	0.1	GO:0060137	maternal process involved in parturition(GO:0060137)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.1	GO:2000535	entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0	0.0	GO:0009597	detection of virus(GO:0009597)
0.0	0.1	GO:0010499	proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.0	0.0	GO:0051572	negative regulation of histone H3-K4 methylation(GO:0051572)
0.0	0.1	GO:0060075	regulation of resting membrane potential(GO:0060075)
0.0	0.1	GO:0061302	smooth muscle cell-matrix adhesion(GO:0061302)
0.0	0.1	GO:0051919	positive regulation of fibrinolysis(GO:0051919)
0.0	0.1	GO:0006933	negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0	0.0	GO:0001306	age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.0	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0	0.1	GO:1902373	negative regulation of mRNA catabolic process(GO:1902373)
0.0	0.0	GO:0006547	histidine metabolic process(GO:0006547)
0.0	0.1	GO:0010757	negative regulation of plasminogen activation(GO:0010757)
0.0	0.0	GO:1903265	positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0	0.1	GO:1904996	positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0	0.1	GO:0032494	response to peptidoglycan(GO:0032494)
0.0	0.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.0	GO:1901859	negative regulation of mitochondrial DNA metabolic process(GO:1901859)
0.0	0.1	GO:0001842	neural fold formation(GO:0001842)
0.0	0.0	GO:0032763	regulation of mast cell cytokine production(GO:0032763)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0000056	ribosomal small subunit export from nucleus(GO:0000056)
0.0	0.1	GO:0030913	paranodal junction assembly(GO:0030913)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.0	GO:0003162	atrioventricular node development(GO:0003162)
0.0	0.0	GO:0051088	PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.0	0.1	GO:0016338	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.0	0.1	GO:0051533	positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0007039	protein catabolic process in the vacuole(GO:0007039)
0.0	0.1	GO:0006851	mitochondrial calcium ion transport(GO:0006851)
0.0	0.0	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:0015670	carbon dioxide transport(GO:0015670)
0.0	0.1	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0	0.0	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	0.0	GO:0030997	regulation of centriole-centriole cohesion(GO:0030997)
0.0	0.0	GO:2001032	regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0	0.0	GO:0006566	threonine metabolic process(GO:0006566)
0.0	0.0	GO:0051466	positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.0	0.0	GO:0006438	valyl-tRNA aminoacylation(GO:0006438)
0.0	0.0	GO:1903423	positive regulation of synaptic vesicle recycling(GO:1903423)
0.0	0.1	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.1	GO:0006348	chromatin silencing at telomere(GO:0006348)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.0	GO:0021586	pons maturation(GO:0021586)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:0048496	maintenance of organ identity(GO:0048496)
0.0	0.0	GO:2000143	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:0006203	dGTP catabolic process(GO:0006203)
0.0	0.0	GO:0018894	dibenzo-p-dioxin metabolic process(GO:0018894)
0.0	0.0	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.0	GO:0015755	fructose transport(GO:0015755)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:0061469	regulation of type B pancreatic cell proliferation(GO:0061469)
0.0	0.0	GO:0071288	cellular response to mercury ion(GO:0071288)
0.0	0.1	GO:0036297	interstrand cross-link repair(GO:0036297)
0.0	0.0	GO:0002414	immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0	0.0	GO:0007084	mitotic nuclear envelope reassembly(GO:0007084)
0.0	0.3	GO:0015701	bicarbonate transport(GO:0015701)
0.0	0.0	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0032876	negative regulation of DNA endoreduplication(GO:0032876)
0.0	0.2	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:0086017	Purkinje myocyte action potential(GO:0086017)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.0	GO:0044805	lysosomal microautophagy(GO:0016237) piecemeal microautophagy of nucleus(GO:0034727) late nucleophagy(GO:0044805)
0.0	0.0	GO:0019230	proprioception(GO:0019230)
0.0	0.0	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.0	GO:0019344	cysteine biosynthetic process(GO:0019344)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.0	GO:0032776	DNA methylation on cytosine within a CG sequence(GO:0010424) DNA methylation on cytosine(GO:0032776)
0.0	0.0	GO:0090361	platelet-derived growth factor production(GO:0090360) regulation of platelet-derived growth factor production(GO:0090361)
0.0	0.0	GO:0006787	porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015)
0.0	0.0	GO:2000152	regulation of ubiquitin-specific protease activity(GO:2000152)
0.0	0.1	GO:0006776	vitamin A metabolic process(GO:0006776)
0.0	0.0	GO:0001887	selenium compound metabolic process(GO:0001887)
0.0	0.0	GO:1902564	negative regulation of neutrophil activation(GO:1902564)
0.0	0.0	GO:0002025	vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure(GO:0002025)
0.0	0.1	GO:0051013	microtubule severing(GO:0051013)
0.0	0.1	GO:0070389	chaperone cofactor-dependent protein refolding(GO:0070389)
0.0	0.1	GO:0021523	somatic motor neuron differentiation(GO:0021523)
0.0	0.1	GO:0007207	adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.0	0.1	GO:0010961	cellular magnesium ion homeostasis(GO:0010961)
0.0	0.2	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.0	0.0	GO:1902837	amino acid import into cell(GO:1902837)
0.0	0.0	GO:0008228	opsonization(GO:0008228)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0005745	m-AAA complex(GO:0005745)
0.1	GO:0035985	senescence-associated heterochromatin focus(GO:0035985)
0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.2	GO:0005577	fibrinogen complex(GO:0005577)
0.1	GO:0089701	U2AF(GO:0089701)
0.1	GO:0005955	calcineurin complex(GO:0005955)
0.1	GO:0097057	TRAF2-GSTP1 complex(GO:0097057)
0.1	GO:0016281	eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.1	GO:0031467	Cul7-RING ubiquitin ligase complex(GO:0031467)
0.1	GO:0016589	NURF complex(GO:0016589)
0.0	GO:0005658	alpha DNA polymerase:primase complex(GO:0005658)
0.1	GO:0005869	dynactin complex(GO:0005869)
0.1	GO:0071141	SMAD protein complex(GO:0071141)
0.1	GO:0034363	intermediate-density lipoprotein particle(GO:0034363)
0.1	GO:0005642	annulate lamellae(GO:0005642)
0.1	GO:0031371	ubiquitin conjugating enzyme complex(GO:0031371)
0.0	GO:0097443	sorting endosome(GO:0097443)
0.1	GO:0042405	nuclear inclusion body(GO:0042405)
0.0	GO:0061574	ASAP complex(GO:0061574)
0.1	GO:0070531	BRCA1-A complex(GO:0070531)
0.2	GO:0090545	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	GO:0016533	cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0	GO:0031262	Ndc80 complex(GO:0031262)
0.0	GO:0035061	interchromatin granule(GO:0035061)
0.0	GO:0043259	laminin-10 complex(GO:0043259)
0.0	GO:0030313	cell outer membrane(GO:0009279) cell envelope(GO:0030313) external encapsulating structure part(GO:0044462)
0.0	GO:1990246	uniplex complex(GO:1990246)
0.0	GO:0044308	axonal spine(GO:0044308)
0.1	GO:0005885	Arp2/3 protein complex(GO:0005885)
0.1	GO:0033180	proton-transporting V-type ATPase, V1 domain(GO:0033180)

Gene overrepresentation in molecular function category:

Total log-likelihood	Term	Description
0.2	GO:0070290	N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1	GO:0015319	sodium:inorganic phosphate symporter activity(GO:0015319)
0.3	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.1	GO:0004829	threonine-tRNA ligase activity(GO:0004829)
0.1	GO:0019770	IgG receptor activity(GO:0019770)
0.1	GO:0052650	NADP-retinol dehydrogenase activity(GO:0052650)
0.1	GO:0051575	5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.1	GO:0005432	calcium:sodium antiporter activity(GO:0005432)
0.1	GO:0031800	type 3 metabotropic glutamate receptor binding(GO:0031800)
0.1	GO:0061665	SUMO ligase activity(GO:0061665)
0.1	GO:1990188	euchromatin binding(GO:1990188)
0.1	GO:0004630	phospholipase D activity(GO:0004630)
0.1	GO:0042296	ISG15 transferase activity(GO:0042296)
0.2	GO:0004028	3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1	GO:0050693	LBD domain binding(GO:0050693)
0.1	GO:0034046	poly(G) binding(GO:0034046)
0.1	GO:0070991	medium-chain-acyl-CoA dehydrogenase activity(GO:0070991)
0.1	GO:0050649	testosterone 6-beta-hydroxylase activity(GO:0050649)
0.1	GO:0008297	single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1	GO:0038085	vascular endothelial growth factor binding(GO:0038085)
0.1	GO:0008142	oxysterol binding(GO:0008142)
0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.1	GO:0004528	phosphodiesterase I activity(GO:0004528)
0.0	GO:0004345	glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.1	GO:0004862	cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.2	GO:0015106	bicarbonate transmembrane transporter activity(GO:0015106)
0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.1	GO:0047372	acylglycerol lipase activity(GO:0047372)
0.0	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	GO:0061513	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1	GO:0042910	xenobiotic transporter activity(GO:0042910)
0.1	GO:0018630	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.1	GO:0034902	alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	GO:0004948	calcitonin receptor activity(GO:0004948)
0.0	GO:0004832	valine-tRNA ligase activity(GO:0004832)
0.2	GO:0005186	pheromone activity(GO:0005186)
0.1	GO:0048406	nerve growth factor binding(GO:0048406)
0.1	GO:0017166	vinculin binding(GO:0017166)
0.1	GO:0005534	galactose binding(GO:0005534)
0.0	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	GO:0015065	uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0	GO:0008808	cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572)
0.0	GO:0046573	lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	GO:0004939	beta-adrenergic receptor activity(GO:0004939)
0.0	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.0	GO:0004487	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.1	GO:0016907	G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0	GO:0004703	G-protein coupled receptor kinase activity(GO:0004703)
0.1	GO:0008020	G-protein coupled photoreceptor activity(GO:0008020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	PID A6B1 A6B4 INTEGRIN PATHWAY	a6b1 and a6b4 Integrin signaling
0.0	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1	PID NECTIN PATHWAY	Nectin adhesion pathway
0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.1	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.1	ST STAT3 PATHWAY	STAT3 Pathway
0.0	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Total log-likelihood	Term	Description
0.1	REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION	Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.1	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.3	REACTOME SULFUR AMINO ACID METABOLISM	Genes involved in Sulfur amino acid metabolism
0.0	REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR	Genes involved in Thromboxane signalling through TP receptor
0.2	REACTOME PEROXISOMAL LIPID METABOLISM	Genes involved in Peroxisomal lipid metabolism
0.0	REACTOME PLATELET SENSITIZATION BY LDL	Genes involved in Platelet sensitization by LDL
0.1	REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS	Genes involved in Tandem pore domain potassium channels
0.1	REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS	Genes involved in Phosphorylation of CD3 and TCR zeta chains

Results for Tfcp2

Z-value: 0.88

Motif logo

Transcription factors associated with Tfcp2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Activity of the Tfcp2 motif across conditions

Conditions sorted by the z-value of the Tfcp2 motif activity

Top target CREs of the motif:

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfcp2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: