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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Tgif2_Tgif2lx1_Tgif2lx2

Z-value: 1.12

Motif logo

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Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2

Gene Symbol Gene ID Gene Info
Tgif2
ENSMUSG00000062175.7 TGFB-induced factor homeobox 2
Tgif2lx1
ENSMUSG00000061283.4 TGFB-induced factor homeobox 2-like, X-linked 1
Tgif2lx2
ENSMUSG00000063242.6 TGFB-induced factor homeobox 2-like, X-linked 2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr2_156841774_156841939Tgif28340.368473-0.394.4e-01Click!
chr2_156850520_156850838Tgif21570.8526830.236.7e-01Click!
chr2_156842028_156842195Tgif210890.2787580.118.3e-01Click!

Activity of the Tgif2_Tgif2lx1_Tgif2lx2 motif across conditions

Conditions sorted by the z-value of the Tgif2_Tgif2lx1_Tgif2lx2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr11_7200350_7200584 1.28 Igfbp1
 insulin-like growth factor binding protein 1
 2685
 0.24
chr7_145087928_145088130 1.24 Gm45181
 predicted gene 45181
 74967
 0.09
chr19_47222639_47222810 1.08 Gm50339
 predicted gene, 50339
 815
 0.48
chr15_100112289_100112692 0.92 4930478M13Rik
 RIKEN cDNA 4930478M13 gene
 4329
 0.17
chr2_69406819_69407032 0.81 Dhrs9
 dehydrogenase/reductase (SDR family) member 9
 26480
 0.18
chr6_96536704_96536871 0.79 Gm26011
 predicted gene, 26011
 24077
 0.25
chr1_106234376_106234538 0.70 Gm38235
 predicted gene, 38235
 15143
 0.2
chr14_51102195_51102364 0.70 Rnase4
 ribonuclease, RNase A family 4
 5920
 0.08
chr13_48916144_48916308 0.69 Phf2
 PHD finger protein 2
 45107
 0.13
chr8_119399377_119399539 0.66 Mlycd
 malonyl-CoA decarboxylase
 4560
 0.18
chr8_123736984_123737175 0.66 Gm45781
 predicted gene 45781
 1937
 0.14
chr6_87428535_87428790 0.64 Bmp10
 bone morphogenetic protein 10
 332
 0.85
chr3_104796399_104796698 0.63 Rhoc
 ras homolog family member C
 4565
 0.1
chr9_112743581_112744166 0.61 Gm24957
 predicted gene, 24957
 221344
 0.02
chr5_120103213_120103364 0.61 Rbm19
 RNA binding motif protein 19
 13177
 0.19
chr8_119428895_119429065 0.60 Osgin1
 oxidative stress induced growth inhibitor 1
 5144
 0.17
chr10_95408627_95408789 0.59 Socs2
 suppressor of cytokine signaling 2
 4026
 0.16
chr1_9906956_9907361 0.55 Mcmdc2
 minichromosome maintenance domain containing 2
 1480
 0.29
chr11_69379820_69379976 0.54 Chd3
 chromodomain helicase DNA binding protein 3
 10492
 0.07
chr16_16225035_16225410 0.54 Pkp2
 plakophilin 2
 11904
 0.19
chr3_129887879_129888048 0.54 Pla2g12a
 phospholipase A2, group XIIA
 4867
 0.17
chr15_69164972_69165161 0.53 4930573C08Rik
 RIKEN cDNA 4930573C08 gene
 69933
 0.12
chr2_28525746_28525944 0.51 Ralgds
 ral guanine nucleotide dissociation stimulator
 2005
 0.19
chr2_38515308_38515472 0.50 Nek6
 NIMA (never in mitosis gene a)-related expressed kinase 6
 764
 0.53
chr8_126806262_126806425 0.50 A630001O12Rik
 RIKEN cDNA A630001O12 gene
 32890
 0.16
chr10_81557608_81557764 0.49 Tle5
 TLE family member 5, transcriptional modulator
 1802
 0.15
chr5_129895959_129896119 0.49 Zbed5
 zinc finger, BED type containing 5
 261
 0.82
chr2_167830912_167831104 0.48 1200007C13Rik
 RIKEN cDNA 1200007C13 gene
 2638
 0.23
chr7_58746856_58747052 0.48 Gm44937
 predicted gene 44937
 26755
 0.16
chr9_107667921_107668276 0.47 Slc38a3
 solute carrier family 38, member 3
 672
 0.46
chr8_11221370_11221555 0.47 Col4a1
 collagen, type IV, alpha 1
 4193
 0.21
chr2_164421410_164421570 0.47 Matn4
 matrilin 4
 16330
 0.08
chr14_25487639_25487838 0.47 Gm47921
 predicted gene, 47921
 7684
 0.14
chr3_101500478_101500642 0.46 Gm42538
 predicted gene 42538
 73624
 0.07
chr16_22897044_22897510 0.46 Ahsg
 alpha-2-HS-glycoprotein
 2413
 0.17
chr9_119478527_119478678 0.46 Exog
 endo/exonuclease (5'-3'), endonuclease G-like
 33615
 0.12
chr1_128705220_128705376 0.46 Gm29599
 predicted gene 29599
 45628
 0.15
chr8_46499145_46499431 0.45 Acsl1
 acyl-CoA synthetase long-chain family member 1
 6456
 0.17
chr1_176874134_176874434 0.45 Gm25993
 predicted gene, 25993
 5550
 0.12
chr11_31676998_31677176 0.45 Bod1
 biorientation of chromosomes in cell division 1
 5202
 0.25
chr11_98772948_98773272 0.45 Nr1d1
 nuclear receptor subfamily 1, group D, member 1
 2223
 0.16
chr7_35123689_35123850 0.44 Gm45091
 predicted gene 45091
 4164
 0.11
chr12_112561481_112561648 0.44 Inf2
 inverted formin, FH2 and WH2 domain containing
 27220
 0.12
chr9_118101918_118102083 0.43 Azi2
 5-azacytidine induced gene 2
 42944
 0.13
chr6_88778293_88778444 0.43 Gm43937
 predicted gene, 43937
 9083
 0.12
chr4_119882590_119882770 0.43 Hivep3
 human immunodeficiency virus type I enhancer binding protein 3
 68185
 0.12
chr3_84015637_84015957 0.43 Tmem131l
 transmembrane 131 like
 24331
 0.2
chr2_146577293_146577459 0.43 4933406D12Rik
 RIKEN cDNA 4933406D12 gene
 34445
 0.2
chr16_56063021_56063172 0.43 Gm24047
 predicted gene, 24047
 7467
 0.12
chr14_61045882_61046048 0.43 Tnfrsf19
 tumor necrosis factor receptor superfamily, member 19
 504
 0.81
chr1_118479315_118479504 0.43 Gm28466
 predicted gene 28466
 182
 0.92
chr9_75436041_75436202 0.42 Leo1
 Leo1, Paf1/RNA polymerase II complex component
 5403
 0.13
chr2_163100058_163100224 0.42 Gm22174
 predicted gene, 22174
 7242
 0.13
chr14_30919586_30919927 0.42 Itih3
 inter-alpha trypsin inhibitor, heavy chain 3
 3793
 0.13
chr5_139358617_139359046 0.42 Cyp2w1
 cytochrome P450, family 2, subfamily w, polypeptide 1
 4255
 0.13
chr9_25543888_25544039 0.42 Gm25861
 predicted gene, 25861
 4758
 0.23
chr16_80273340_80273491 0.41 Gm23083
 predicted gene, 23083
 136063
 0.05
chr8_68025403_68025869 0.41 Gm22018
 predicted gene, 22018
 15296
 0.22
chr10_93520708_93521069 0.41 Amdhd1
 amidohydrolase domain containing 1
 19145
 0.12
chr8_105748797_105748959 0.41 Gfod2
 glucose-fructose oxidoreductase domain containing 2
 9718
 0.1
chr11_5526651_5526819 0.40 Xbp1
 X-box binding protein 1
 4812
 0.14
chr17_73786615_73786813 0.39 Ehd3
 EH-domain containing 3
 17420
 0.2
chr9_61421745_61421905 0.39 Tle3
 transducin-like enhancer of split 3
 11888
 0.18
chr18_46993175_46993356 0.39 Gm22791
 predicted gene, 22791
 7784
 0.15
chr11_3182131_3182388 0.38 Sfi1
 Sfi1 homolog, spindle assembly associated (yeast)
 4766
 0.13
chr5_114982798_114982985 0.38 1810017P11Rik
 RIKEN cDNA 1810017P11 gene
 7435
 0.09
chr18_81199680_81199982 0.38 4930594M17Rik
 RIKEN cDNA 4930594M17 gene
 36235
 0.17
chr15_36902674_36902830 0.38 Gm10384
 predicted gene 10384
 22936
 0.14
chr6_85918490_85918716 0.37 Tprkb
 Tp53rk binding protein
 2805
 0.1
chr1_54840038_54840202 0.37 Ankrd44
 ankyrin repeat domain 44
 26677
 0.18
chr10_127591032_127591346 0.37 Gm16217
 predicted gene 16217
 5359
 0.11
chr9_78175590_78175749 0.37 C920006O11Rik
 RIKEN cDNA C920006O11 gene
 245
 0.87
chr12_86817069_86817235 0.36 Gm10095
 predicted gene 10095
 29315
 0.15
chr10_69288238_69288393 0.36 Rhobtb1
 Rho-related BTB domain containing 1
 8857
 0.18
chr6_71235183_71235374 0.36 Smyd1
 SET and MYND domain containing 1
 18404
 0.1
chr19_4441349_4441500 0.36 A930001C03Rik
 RIKEN cDNA A930001C03 gene
 1865
 0.2
chr7_140771105_140771348 0.36 Cyp2e1
 cytochrome P450, family 2, subfamily e, polypeptide 1
 6745
 0.09
chr17_71202252_71202409 0.36 Lpin2
 lipin 2
 2324
 0.26
chr18_47329689_47330033 0.35 Sema6a
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
 3465
 0.29
chr15_97377850_97378467 0.35 Pced1b
 PC-esterase domain containing 1B
 16941
 0.24
chr11_118424849_118425071 0.35 C1qtnf1
 C1q and tumor necrosis factor related protein 1
 3243
 0.17
chr9_58295819_58296113 0.35 Loxl1
 lysyl oxidase-like 1
 17220
 0.13
chr2_160730308_160730465 0.35 Plcg1
 phospholipase C, gamma 1
 914
 0.55
chr2_169790587_169791240 0.35 Tshz2
 teashirt zinc finger family member 2
 93980
 0.08
chr6_125082928_125083092 0.34 2010008C14Rik
 RIKEN cDNA 2010008C14 gene
 427
 0.62
chr11_34116764_34116915 0.34 4930469K13Rik
 RIKEN cDNA 4930469K13 gene
 18285
 0.17
chr19_42690384_42690568 0.34 Gm25216
 predicted gene, 25216
 9426
 0.19
chr4_81673472_81673626 0.34 Gm11411
 predicted gene 11411
 22892
 0.24
chr8_126847749_126848310 0.34 A630001O12Rik
 RIKEN cDNA A630001O12 gene
 8796
 0.2
chr4_58479203_58479397 0.33 Gm12577
 predicted gene 12577
 4525
 0.22
chr18_80933373_80933681 0.33 Atp9b
 ATPase, class II, type 9B
 456
 0.78
chr7_28931496_28931685 0.33 Gm44699
 predicted gene 44699
 11938
 0.1
chr8_10859650_10859809 0.33 Gm32540
 predicted gene, 32540
 6457
 0.13
chr11_82011146_82011303 0.32 Gm31522
 predicted gene, 31522
 8743
 0.13
chr7_140763552_140763973 0.32 Cyp2e1
 cytochrome P450, family 2, subfamily e, polypeptide 1
 23
 0.95
chr7_19864157_19864332 0.32 Ceacam16
 carcinoembryonic antigen-related cell adhesion molecule 16
 2945
 0.1
chr4_62393542_62393745 0.32 Slc31a1
 solute carrier family 31, member 1
 8142
 0.12
chr7_68696821_68697010 0.32 Gm44692
 predicted gene 44692
 29552
 0.18
chr1_134520125_134520290 0.32 Gm29376
 predicted gene 29376
 229
 0.86
chr10_84811999_84812153 0.32 Gm24226
 predicted gene, 24226
 893
 0.64
chr13_104060391_104060569 0.32 Nln
 neurolysin (metallopeptidase M3 family)
 1374
 0.46
chr8_13350961_13351112 0.32 Tfdp1
 transcription factor Dp 1
 11362
 0.12
chr7_105615844_105616248 0.31 Trim3
 tripartite motif-containing 3
 1980
 0.16
chr11_119219937_119220100 0.31 Gm11752
 predicted gene 11752
 142
 0.92
chr1_165594960_165595125 0.31 Gm38210
 predicted gene, 38210
 9859
 0.11
chr13_114923473_114923635 0.31 Itga2
 integrin alpha 2
 8546
 0.22
chr11_59640294_59640451 0.31 Mprip
 myosin phosphatase Rho interacting protein
 20933
 0.11
chr19_36731471_36731641 0.31 Ppp1r3c
 protein phosphatase 1, regulatory subunit 3C
 5097
 0.23
chr7_145044142_145044344 0.31 Ccnd1
 cyclin D1
 104318
 0.05
chr10_18401012_18401316 0.31 Nhsl1
 NHS-like 1
 6474
 0.25
chr6_43853589_43853745 0.31 Gm7783
 predicted gene 7783
 3237
 0.31
chr6_93758200_93758371 0.31 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 34254
 0.18
chr1_72790444_72790955 0.31 Igfbp2
 insulin-like growth factor binding protein 2
 33804
 0.15
chr3_41582728_41583000 0.30 Jade1
 jade family PHD finger 1
 2008
 0.28
chr11_100322740_100322903 0.30 Eif1
 eukaryotic translation initiation factor 1
 1937
 0.15
chr7_137411009_137411178 0.30 9430038I01Rik
 RIKEN cDNA 9430038I01 gene
 331
 0.89
chr5_111336301_111336538 0.30 Pitpnb
 phosphatidylinositol transfer protein, beta
 5612
 0.19
chr18_84376572_84376752 0.30 Gm37216
 predicted gene, 37216
 516
 0.84
chr1_192392344_192392537 0.29 Kcnh1
 potassium voltage-gated channel, subfamily H (eag-related), member 1
 42300
 0.19
chr2_33200439_33200604 0.29 Gm23546
 predicted gene, 23546
 11420
 0.14
chr9_6891499_6891736 0.29 Dync2h1
 dynein cytoplasmic 2 heavy chain 1
 65072
 0.13
chr2_113479270_113479457 0.29 Gm44465
 predicted gene, 44465
 2542
 0.24
chr9_107612485_107612643 0.29 Sema3b
 sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
 3335
 0.08
chr4_55750335_55750505 0.29 Gm12506
 predicted gene 12506
 145271
 0.04
chr19_12004611_12004803 0.29 Olfr1421-ps1
 olfactory receptor 1421, pseudogene 1
 15468
 0.08
chr7_24487486_24487637 0.29 Cadm4
 cell adhesion molecule 4
 5538
 0.09
chr10_84872038_84872201 0.28 Rfx4
 regulatory factor X, 4 (influences HLA class II expression)
 33971
 0.16
chr13_63243697_63243864 0.28 Gm47586
 predicted gene, 47586
 441
 0.69
chr1_34388067_34388244 0.28 Gm5266
 predicted gene 5266
 20784
 0.09
chr6_128481290_128481511 0.28 Pzp
 PZP, alpha-2-macroglobulin like
 6455
 0.09
chr3_138240414_138240729 0.28 0610031O16Rik
 RIKEN cDNA 0610031O16 gene
 166
 0.88
chr2_12429797_12430138 0.28 Gm13321
 predicted gene 13321
 7941
 0.18
chr18_60660075_60660394 0.28 Synpo
 synaptopodin
 92
 0.97
chr3_91483300_91483476 0.28 S100a7l2
 S100 calcium binding protein A7 like 2
 392585
 0.01
chr10_80917355_80917522 0.27 Lmnb2
 lamin B2
 413
 0.7
chr10_59916266_59916428 0.27 Ddit4
 DNA-damage-inducible transcript 4
 35487
 0.11
chr5_53437072_53437250 0.27 Gm26486
 predicted gene, 26486
 18588
 0.17
chr2_68873804_68874167 0.27 Cers6
 ceramide synthase 6
 12399
 0.14
chr7_80194026_80194200 0.27 Sema4b
 sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
 4328
 0.12
chr11_70404879_70405056 0.27 Pelp1
 proline, glutamic acid and leucine rich protein 1
 5061
 0.09
chr8_105796118_105796294 0.27 Ranbp10
 RAN binding protein 10
 30999
 0.07
chr12_112111213_112111675 0.27 Aspg
 asparaginase
 1496
 0.24
chr13_63256313_63256480 0.27 Gm47603
 predicted gene, 47603
 832
 0.41
chr15_64155705_64155901 0.27 Asap1
 ArfGAP with SH3 domain, ankyrin repeat and PH domain1
 31997
 0.18
chrX_85793507_85793673 0.27 Gm6964
 predicted gene 6964
 530
 0.68
chrX_13062821_13063132 0.27 Usp9x
 ubiquitin specific peptidase 9, X chromosome
 8522
 0.19
chr8_83747944_83748146 0.26 Gm45778
 predicted gene 45778
 1459
 0.29
chr15_83524040_83524213 0.26 Bik
 BCL2-interacting killer
 2736
 0.16
chr17_42924837_42925015 0.26 Cd2ap
 CD2-associated protein
 48261
 0.17
chr16_26695984_26696378 0.26 Il1rap
 interleukin 1 receptor accessory protein
 26253
 0.23
chr17_56332362_56332517 0.26 Kdm4b
 lysine (K)-specific demethylase 4B
 6348
 0.12
chr11_74869463_74869647 0.26 Sgsm2
 small G protein signaling modulator 2
 463
 0.64
chr7_130248786_130248946 0.26 Fgfr2
 fibroblast growth factor receptor 2
 12991
 0.27
chr13_74502209_74502494 0.26 Gm49763
 predicted gene, 49763
 8208
 0.1
chr11_112810518_112810820 0.26 Gm11681
 predicted gene 11681
 11661
 0.18
chr5_112134275_112134433 0.26 1700016B01Rik
 RIKEN cDNA 1700016B01 gene
 21883
 0.18
chr19_3685828_3686010 0.26 Lrp5
 low density lipoprotein receptor-related protein 5
 637
 0.59
chr8_122003719_122003880 0.26 Banp
 BTG3 associated nuclear protein
 2952
 0.19
chr11_5741148_5741583 0.26 Urgcp
 upregulator of cell proliferation
 215
 0.9
chr18_81199291_81199673 0.25 4930594M17Rik
 RIKEN cDNA 4930594M17 gene
 36584
 0.17
chr5_125127560_125127724 0.25 Ncor2
 nuclear receptor co-repressor 2
 2742
 0.29
chr7_107633306_107633481 0.25 5330417H12Rik
 RIKEN cDNA 5330417H12 gene
 8232
 0.16
chr16_21549898_21550055 0.25 Vps8
 VPS8 CORVET complex subunit
 13091
 0.25
chr19_16498717_16499020 0.25 Gm8222
 predicted gene 8222
 7804
 0.21
chr8_46332765_46332934 0.25 Gm45255
 predicted gene 45255
 19048
 0.11
chrX_102478577_102478728 0.24 Hdac8
 histone deacetylase 8
 26089
 0.19
chr5_117166861_117167023 0.24 n-R5s174
 nuclear encoded rRNA 5S 174
 29613
 0.12
chr11_62568400_62568605 0.24 Gm12280
 predicted gene 12280
 2119
 0.14
chr12_71370184_71370345 0.24 1700083H02Rik
 RIKEN cDNA 1700083H02 gene
 13944
 0.15
chr17_31930278_31930580 0.24 Gm30571
 predicted gene, 30571
 17763
 0.12
chr7_99141254_99141466 0.24 Uvrag
 UV radiation resistance associated gene
 219
 0.5
chr7_50868844_50869021 0.24 Gm9343
 predicted gene 9343
 74222
 0.09
chr5_53957420_53957607 0.24 Gm43266
 predicted gene 43266
 39069
 0.14
chr4_45499631_45499795 0.24 Gm22518
 predicted gene, 22518
 839
 0.56
chr5_32735922_32736077 0.24 Gm43695
 predicted gene 43695
 3335
 0.14
chr3_94310992_94311165 0.24 Them4
 thioesterase superfamily member 4
 942
 0.35
chr5_130761960_130762123 0.24 Gm23761
 predicted gene, 23761
 20660
 0.24
chr1_155886750_155887199 0.24 Cep350
 centrosomal protein 350
 960
 0.44
chr14_65100574_65100746 0.24 Extl3
 exostosin-like glycosyltransferase 3
 2554
 0.29
chr17_79904674_79904846 0.24 Atl2
 atlastin GTPase 2
 8637
 0.18
chr5_92773632_92773840 0.24 Mir1961
 microRNA 1961
 14826
 0.18
chr16_21642073_21642273 0.24 Vps8
 VPS8 CORVET complex subunit
 14542
 0.21
chr4_134931334_134931504 0.23 Syf2
 SYF2 homolog, RNA splicing factor (S. cerevisiae)
 409
 0.81
chr11_45145769_45145947 0.23 Gm12160
 predicted gene 12160
 15085
 0.2
chr13_33935183_33935334 0.23 1110046J04Rik
 RIKEN cDNA 1110046J04 gene
 309
 0.67
chr16_28989883_28990229 0.23 Gm8253
 predicted gene 8253
 38701
 0.19
chr2_59193239_59193408 0.23 Pkp4
 plakophilin 4
 7451
 0.22
chr4_82621551_82621752 0.23 Gm11268
 predicted gene 11268
 20749
 0.19
chr9_70672050_70672218 0.23 Adam10
 a disintegrin and metallopeptidase domain 10
 6863
 0.18
chr5_114772969_114773120 0.23 Git2
 GIT ArfGAP 2
 390
 0.68
chr3_18080789_18080940 0.23 Gm23726
 predicted gene, 23726
 11538
 0.2
chr4_149887083_149887262 0.23 Gm13070
 predicted gene 13070
 16834
 0.13
chr2_93823530_93823821 0.23 Ext2
 exostosin glycosyltransferase 2
 1107
 0.46
chr8_115089778_115090403 0.23 Gm22556
 predicted gene, 22556
 37177
 0.23
chr9_48592438_48592815 0.23 Nnmt
 nicotinamide N-methyltransferase
 4749
 0.26
chr1_40221808_40222119 0.22 Il1r1
 interleukin 1 receptor, type I
 3117
 0.26
chr15_27800508_27800681 0.22 Trio
 triple functional domain (PTPRF interacting)
 11956
 0.22
chr3_57435613_57435790 0.22 Tm4sf4
 transmembrane 4 superfamily member 4
 10387
 0.22
chr7_48883645_48884044 0.22 E2f8
 E2F transcription factor 8
 2248
 0.2
chr4_149098057_149098222 0.22 Pex14
 peroxisomal biogenesis factor 14
 1670
 0.22

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Tgif2_Tgif2lx1_Tgif2lx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.3 GO:0006868 glutamine transport(GO:0006868)
0.1 0.3 GO:1904393 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.1 0.1 GO:0060847 endothelial cell fate specification(GO:0060847)
0.0 0.1 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0 0.2 GO:1903626 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.3 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0010728 regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0 0.2 GO:0052805 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.1 GO:0061502 early endosome to recycling endosome transport(GO:0061502)
0.0 0.2 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.0 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.1 GO:0051126 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0 0.1 GO:0002525 acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0 0.1 GO:0070669 response to interleukin-2(GO:0070669)
0.0 0.2 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.1 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.1 GO:0072367 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.3 GO:0072600 establishment of protein localization to Golgi(GO:0072600)
0.0 0.1 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0 0.1 GO:1902744 negative regulation of lamellipodium organization(GO:1902744)
0.0 0.2 GO:0072364 regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0 0.0 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.3 GO:0046599 regulation of centriole replication(GO:0046599)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.1 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.1 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.3 GO:0031998 regulation of fatty acid beta-oxidation(GO:0031998)
0.0 0.1 GO:0050923 regulation of negative chemotaxis(GO:0050923)
0.0 0.0 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484)
0.0 0.0 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.0 0.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.1 GO:0071673 regulation of smooth muscle cell chemotaxis(GO:0071671) positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.1 GO:0006681 galactosylceramide metabolic process(GO:0006681)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:2000468 regulation of peroxidase activity(GO:2000468)
0.0 0.1 GO:0042117 monocyte activation(GO:0042117)
0.0 0.1 GO:0051771 negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.1 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.0 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0 0.2 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.2 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 0.1 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.0 0.1 GO:0014744 positive regulation of muscle adaptation(GO:0014744)
0.0 0.1 GO:0001555 oocyte growth(GO:0001555)
0.0 0.0 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655)
0.0 0.0 GO:0060486 Clara cell differentiation(GO:0060486)
0.0 0.1 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0 0.0 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0 0.1 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.0 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.0 GO:0009972 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0 0.1 GO:0051031 tRNA transport(GO:0051031)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:0036484 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0 0.0 GO:0038171 cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.0 GO:0043321 regulation of natural killer cell degranulation(GO:0043321)
0.0 0.0 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.0 0.0 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.0 GO:0002554 serotonin secretion by platelet(GO:0002554)
0.0 0.1 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.0 0.0 GO:0048549 positive regulation of pinocytosis(GO:0048549)
0.0 0.1 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.0 GO:0018879 biphenyl metabolic process(GO:0018879)
0.0 0.2 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.1 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.0 GO:0002434 immune complex clearance(GO:0002434)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0 0.0 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0045053 protein retention in Golgi apparatus(GO:0045053)
0.0 0.0 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.0 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.0 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:1903551 regulation of extracellular exosome assembly(GO:1903551)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:1904526 regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0 0.1 GO:0046618 drug export(GO:0046618)
0.0 0.0 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.0 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.0 0.0 GO:0015886 heme transport(GO:0015886)
0.0 0.1 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.1 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.0 GO:1990314 cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0 0.0 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0015825 L-serine transport(GO:0015825)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.0 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.0 GO:0021698 cerebellar cortex structural organization(GO:0021698)
0.0 0.1 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.0 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.0 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.0 GO:0045658 regulation of neutrophil differentiation(GO:0045658)
0.0 0.1 GO:0001302 replicative cell aging(GO:0001302)
0.0 0.1 GO:0061154 endothelial tube morphogenesis(GO:0061154)
0.0 0.0 GO:0023021 termination of signal transduction(GO:0023021)
0.0 0.0 GO:0002432 granuloma formation(GO:0002432)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0060633 negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0 0.0 GO:1901656 glycoside transport(GO:1901656)
0.0 0.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.0 GO:0060468 prevention of polyspermy(GO:0060468)
0.0 0.1 GO:0015884 folic acid transport(GO:0015884)
0.0 0.2 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.0 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.0 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:0016942 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 0.1 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0020016 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.1 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 0.2 GO:0005767 secondary lysosome(GO:0005767)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.1 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0043259 laminin-10 complex(GO:0043259)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.0 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.0 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.0 GO:0031523 Myb complex(GO:0031523)
0.0 0.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.0 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.0 GO:0042825 TAP complex(GO:0042825)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.2 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.0 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0030673 axolemma(GO:0030673)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0031433 telethonin binding(GO:0031433)
0.1 0.3 GO:0015186 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0005131 growth hormone receptor binding(GO:0005131)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0 0.2 GO:0004673 protein histidine kinase activity(GO:0004673)
0.0 0.2 GO:0018655 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0 0.1 GO:0015252 hydrogen ion channel activity(GO:0015252)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.1 GO:0008390 testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.3 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.0 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.1 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0 0.1 GO:0038064 collagen receptor activity(GO:0038064)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.0 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.0 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.0 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.0 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.0 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.0 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.2 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.0 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0004661 protein geranylgeranyltransferase activity(GO:0004661)
0.0 0.0 GO:0080084 RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.1 GO:0005315 inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.0 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.0 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.1 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.0 0.1 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.0 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.0 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.0 PID TCPTP PATHWAY Signaling events mediated by TCPTP
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.2 REACTOME FGFR2C LIGAND BINDING AND ACTIVATION Genes involved in FGFR2c ligand binding and activation
0.0 0.2 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.0 REACTOME SIGNALING BY ERBB2 Genes involved in Signaling by ERBB2
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.1 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.1 REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA Genes involved in Activation of Chaperones by ATF6-alpha
0.0 0.2 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.0 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.0 0.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)