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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Tgif2_Tgif2lx1_Tgif2lx2

Z-value: 1.12

Motif logo

Transcription factors associated with Tgif2_Tgif2lx1_Tgif2lx2

Gene Symbol	Gene ID	Gene Info
Tgif2 Ensembl NCBI MGI UniProt	ENSMUSG00000062175.7	Tgif2
Tgif2lx1 Ensembl NCBI MGI UniProt	ENSMUSG00000061283.4	Tgif2lx1
Tgif2lx2 Ensembl NCBI MGI UniProt	ENSMUSG00000063242.6	Tgif2lx2

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Tgif2	chr2_156841774_156841939	834	0.368473	-0.39	4.4e-01	Click!
Tgif2	chr2_156850520_156850838	157	0.852683	0.23	6.7e-01	Click!
Tgif2	chr2_156842028_156842195	1089	0.278758	0.11	8.3e-01	Click!

Activity of the Tgif2_Tgif2lx1_Tgif2lx2 motif across conditions

Conditions sorted by the z-value of the Tgif2_Tgif2lx1_Tgif2lx2 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr11_7200350_7200584	1.28	Igfbp1	insulin-like growth factor binding protein 1	2685	0.24
chr7_145087928_145088130	1.24	Gm45181	predicted gene 45181	74967	0.09
chr19_47222639_47222810	1.08	Gm50339	predicted gene, 50339	815	0.48
chr15_100112289_100112692	0.92	4930478M13Rik	RIKEN cDNA 4930478M13 gene	4329	0.17
chr2_69406819_69407032	0.81	Dhrs9	dehydrogenase/reductase (SDR family) member 9	26480	0.18
chr6_96536704_96536871	0.79	Gm26011	predicted gene, 26011	24077	0.25
chr1_106234376_106234538	0.70	Gm38235	predicted gene, 38235	15143	0.2
chr14_51102195_51102364	0.70	Rnase4	ribonuclease, RNase A family 4	5920	0.08
chr13_48916144_48916308	0.69	Phf2	PHD finger protein 2	45107	0.13
chr8_119399377_119399539	0.66	Mlycd	malonyl-CoA decarboxylase	4560	0.18
chr8_123736984_123737175	0.66	Gm45781	predicted gene 45781	1937	0.14
chr6_87428535_87428790	0.64	Bmp10	bone morphogenetic protein 10	332	0.85
chr3_104796399_104796698	0.63	Rhoc	ras homolog family member C	4565	0.1
chr9_112743581_112744166	0.61	Gm24957	predicted gene, 24957	221344	0.02
chr5_120103213_120103364	0.61	Rbm19	RNA binding motif protein 19	13177	0.19
chr8_119428895_119429065	0.60	Osgin1	oxidative stress induced growth inhibitor 1	5144	0.17
chr10_95408627_95408789	0.59	Socs2	suppressor of cytokine signaling 2	4026	0.16
chr1_9906956_9907361	0.55	Mcmdc2	minichromosome maintenance domain containing 2	1480	0.29
chr11_69379820_69379976	0.54	Chd3	chromodomain helicase DNA binding protein 3	10492	0.07
chr16_16225035_16225410	0.54	Pkp2	plakophilin 2	11904	0.19
chr3_129887879_129888048	0.54	Pla2g12a	phospholipase A2, group XIIA	4867	0.17
chr15_69164972_69165161	0.53	4930573C08Rik	RIKEN cDNA 4930573C08 gene	69933	0.12
chr2_28525746_28525944	0.51	Ralgds	ral guanine nucleotide dissociation stimulator	2005	0.19
chr2_38515308_38515472	0.50	Nek6	NIMA (never in mitosis gene a)-related expressed kinase 6	764	0.53
chr8_126806262_126806425	0.50	A630001O12Rik	RIKEN cDNA A630001O12 gene	32890	0.16
chr10_81557608_81557764	0.49	Tle5	TLE family member 5, transcriptional modulator	1802	0.15
chr5_129895959_129896119	0.49	Zbed5	zinc finger, BED type containing 5	261	0.82
chr2_167830912_167831104	0.48	1200007C13Rik	RIKEN cDNA 1200007C13 gene	2638	0.23
chr7_58746856_58747052	0.48	Gm44937	predicted gene 44937	26755	0.16
chr9_107667921_107668276	0.47	Slc38a3	solute carrier family 38, member 3	672	0.46
chr8_11221370_11221555	0.47	Col4a1	collagen, type IV, alpha 1	4193	0.21
chr2_164421410_164421570	0.47	Matn4	matrilin 4	16330	0.08
chr14_25487639_25487838	0.47	Gm47921	predicted gene, 47921	7684	0.14
chr3_101500478_101500642	0.46	Gm42538	predicted gene 42538	73624	0.07
chr16_22897044_22897510	0.46	Ahsg	alpha-2-HS-glycoprotein	2413	0.17
chr9_119478527_119478678	0.46	Exog	endo/exonuclease (5'-3'), endonuclease G-like	33615	0.12
chr1_128705220_128705376	0.46	Gm29599	predicted gene 29599	45628	0.15
chr8_46499145_46499431	0.45	Acsl1	acyl-CoA synthetase long-chain family member 1	6456	0.17
chr1_176874134_176874434	0.45	Gm25993	predicted gene, 25993	5550	0.12
chr11_31676998_31677176	0.45	Bod1	biorientation of chromosomes in cell division 1	5202	0.25
chr11_98772948_98773272	0.45	Nr1d1	nuclear receptor subfamily 1, group D, member 1	2223	0.16
chr7_35123689_35123850	0.44	Gm45091	predicted gene 45091	4164	0.11
chr12_112561481_112561648	0.44	Inf2	inverted formin, FH2 and WH2 domain containing	27220	0.12
chr9_118101918_118102083	0.43	Azi2	5-azacytidine induced gene 2	42944	0.13
chr6_88778293_88778444	0.43	Gm43937	predicted gene, 43937	9083	0.12
chr4_119882590_119882770	0.43	Hivep3	human immunodeficiency virus type I enhancer binding protein 3	68185	0.12
chr3_84015637_84015957	0.43	Tmem131l	transmembrane 131 like	24331	0.2
chr2_146577293_146577459	0.43	4933406D12Rik	RIKEN cDNA 4933406D12 gene	34445	0.2
chr16_56063021_56063172	0.43	Gm24047	predicted gene, 24047	7467	0.12
chr14_61045882_61046048	0.43	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	504	0.81
chr1_118479315_118479504	0.43	Gm28466	predicted gene 28466	182	0.92
chr9_75436041_75436202	0.42	Leo1	Leo1, Paf1/RNA polymerase II complex component	5403	0.13
chr2_163100058_163100224	0.42	Gm22174	predicted gene, 22174	7242	0.13
chr14_30919586_30919927	0.42	Itih3	inter-alpha trypsin inhibitor, heavy chain 3	3793	0.13
chr5_139358617_139359046	0.42	Cyp2w1	cytochrome P450, family 2, subfamily w, polypeptide 1	4255	0.13
chr9_25543888_25544039	0.42	Gm25861	predicted gene, 25861	4758	0.23
chr16_80273340_80273491	0.41	Gm23083	predicted gene, 23083	136063	0.05
chr8_68025403_68025869	0.41	Gm22018	predicted gene, 22018	15296	0.22
chr10_93520708_93521069	0.41	Amdhd1	amidohydrolase domain containing 1	19145	0.12
chr8_105748797_105748959	0.41	Gfod2	glucose-fructose oxidoreductase domain containing 2	9718	0.1
chr11_5526651_5526819	0.40	Xbp1	X-box binding protein 1	4812	0.14
chr17_73786615_73786813	0.39	Ehd3	EH-domain containing 3	17420	0.2
chr9_61421745_61421905	0.39	Tle3	transducin-like enhancer of split 3	11888	0.18
chr18_46993175_46993356	0.39	Gm22791	predicted gene, 22791	7784	0.15
chr11_3182131_3182388	0.38	Sfi1	Sfi1 homolog, spindle assembly associated (yeast)	4766	0.13
chr5_114982798_114982985	0.38	1810017P11Rik	RIKEN cDNA 1810017P11 gene	7435	0.09
chr18_81199680_81199982	0.38	4930594M17Rik	RIKEN cDNA 4930594M17 gene	36235	0.17
chr15_36902674_36902830	0.38	Gm10384	predicted gene 10384	22936	0.14
chr6_85918490_85918716	0.37	Tprkb	Tp53rk binding protein	2805	0.1
chr1_54840038_54840202	0.37	Ankrd44	ankyrin repeat domain 44	26677	0.18
chr10_127591032_127591346	0.37	Gm16217	predicted gene 16217	5359	0.11
chr9_78175590_78175749	0.37	C920006O11Rik	RIKEN cDNA C920006O11 gene	245	0.87
chr12_86817069_86817235	0.36	Gm10095	predicted gene 10095	29315	0.15
chr10_69288238_69288393	0.36	Rhobtb1	Rho-related BTB domain containing 1	8857	0.18
chr6_71235183_71235374	0.36	Smyd1	SET and MYND domain containing 1	18404	0.1
chr19_4441349_4441500	0.36	A930001C03Rik	RIKEN cDNA A930001C03 gene	1865	0.2
chr7_140771105_140771348	0.36	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	6745	0.09
chr17_71202252_71202409	0.36	Lpin2	lipin 2	2324	0.26
chr18_47329689_47330033	0.35	Sema6a	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A	3465	0.29
chr15_97377850_97378467	0.35	Pced1b	PC-esterase domain containing 1B	16941	0.24
chr11_118424849_118425071	0.35	C1qtnf1	C1q and tumor necrosis factor related protein 1	3243	0.17
chr9_58295819_58296113	0.35	Loxl1	lysyl oxidase-like 1	17220	0.13
chr2_160730308_160730465	0.35	Plcg1	phospholipase C, gamma 1	914	0.55
chr2_169790587_169791240	0.35	Tshz2	teashirt zinc finger family member 2	93980	0.08
chr6_125082928_125083092	0.34	2010008C14Rik	RIKEN cDNA 2010008C14 gene	427	0.62
chr11_34116764_34116915	0.34	4930469K13Rik	RIKEN cDNA 4930469K13 gene	18285	0.17
chr19_42690384_42690568	0.34	Gm25216	predicted gene, 25216	9426	0.19
chr4_81673472_81673626	0.34	Gm11411	predicted gene 11411	22892	0.24
chr8_126847749_126848310	0.34	A630001O12Rik	RIKEN cDNA A630001O12 gene	8796	0.2
chr4_58479203_58479397	0.33	Gm12577	predicted gene 12577	4525	0.22
chr18_80933373_80933681	0.33	Atp9b	ATPase, class II, type 9B	456	0.78
chr7_28931496_28931685	0.33	Gm44699	predicted gene 44699	11938	0.1
chr8_10859650_10859809	0.33	Gm32540	predicted gene, 32540	6457	0.13
chr11_82011146_82011303	0.32	Gm31522	predicted gene, 31522	8743	0.13
chr7_140763552_140763973	0.32	Cyp2e1	cytochrome P450, family 2, subfamily e, polypeptide 1	23	0.95
chr7_19864157_19864332	0.32	Ceacam16	carcinoembryonic antigen-related cell adhesion molecule 16	2945	0.1
chr4_62393542_62393745	0.32	Slc31a1	solute carrier family 31, member 1	8142	0.12
chr7_68696821_68697010	0.32	Gm44692	predicted gene 44692	29552	0.18
chr1_134520125_134520290	0.32	Gm29376	predicted gene 29376	229	0.86
chr10_84811999_84812153	0.32	Gm24226	predicted gene, 24226	893	0.64
chr13_104060391_104060569	0.32	Nln	neurolysin (metallopeptidase M3 family)	1374	0.46
chr8_13350961_13351112	0.32	Tfdp1	transcription factor Dp 1	11362	0.12
chr7_105615844_105616248	0.31	Trim3	tripartite motif-containing 3	1980	0.16
chr11_119219937_119220100	0.31	Gm11752	predicted gene 11752	142	0.92
chr1_165594960_165595125	0.31	Gm38210	predicted gene, 38210	9859	0.11
chr13_114923473_114923635	0.31	Itga2	integrin alpha 2	8546	0.22
chr11_59640294_59640451	0.31	Mprip	myosin phosphatase Rho interacting protein	20933	0.11
chr19_36731471_36731641	0.31	Ppp1r3c	protein phosphatase 1, regulatory subunit 3C	5097	0.23
chr7_145044142_145044344	0.31	Ccnd1	cyclin D1	104318	0.05
chr10_18401012_18401316	0.31	Nhsl1	NHS-like 1	6474	0.25
chr6_43853589_43853745	0.31	Gm7783	predicted gene 7783	3237	0.31
chr6_93758200_93758371	0.31	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	34254	0.18
chr1_72790444_72790955	0.31	Igfbp2	insulin-like growth factor binding protein 2	33804	0.15
chr3_41582728_41583000	0.30	Jade1	jade family PHD finger 1	2008	0.28
chr11_100322740_100322903	0.30	Eif1	eukaryotic translation initiation factor 1	1937	0.15
chr7_137411009_137411178	0.30	9430038I01Rik	RIKEN cDNA 9430038I01 gene	331	0.89
chr5_111336301_111336538	0.30	Pitpnb	phosphatidylinositol transfer protein, beta	5612	0.19
chr18_84376572_84376752	0.30	Gm37216	predicted gene, 37216	516	0.84
chr1_192392344_192392537	0.29	Kcnh1	potassium voltage-gated channel, subfamily H (eag-related), member 1	42300	0.19
chr2_33200439_33200604	0.29	Gm23546	predicted gene, 23546	11420	0.14
chr9_6891499_6891736	0.29	Dync2h1	dynein cytoplasmic 2 heavy chain 1	65072	0.13
chr2_113479270_113479457	0.29	Gm44465	predicted gene, 44465	2542	0.24
chr9_107612485_107612643	0.29	Sema3b	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B	3335	0.08
chr4_55750335_55750505	0.29	Gm12506	predicted gene 12506	145271	0.04
chr19_12004611_12004803	0.29	Olfr1421-ps1	olfactory receptor 1421, pseudogene 1	15468	0.08
chr7_24487486_24487637	0.29	Cadm4	cell adhesion molecule 4	5538	0.09
chr10_84872038_84872201	0.28	Rfx4	regulatory factor X, 4 (influences HLA class II expression)	33971	0.16
chr13_63243697_63243864	0.28	Gm47586	predicted gene, 47586	441	0.69
chr1_34388067_34388244	0.28	Gm5266	predicted gene 5266	20784	0.09
chr6_128481290_128481511	0.28	Pzp	PZP, alpha-2-macroglobulin like	6455	0.09
chr3_138240414_138240729	0.28	0610031O16Rik	RIKEN cDNA 0610031O16 gene	166	0.88
chr2_12429797_12430138	0.28	Gm13321	predicted gene 13321	7941	0.18
chr18_60660075_60660394	0.28	Synpo	synaptopodin	92	0.97
chr3_91483300_91483476	0.28	S100a7l2	S100 calcium binding protein A7 like 2	392585	0.01
chr10_80917355_80917522	0.27	Lmnb2	lamin B2	413	0.7
chr10_59916266_59916428	0.27	Ddit4	DNA-damage-inducible transcript 4	35487	0.11
chr5_53437072_53437250	0.27	Gm26486	predicted gene, 26486	18588	0.17
chr2_68873804_68874167	0.27	Cers6	ceramide synthase 6	12399	0.14
chr7_80194026_80194200	0.27	Sema4b	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B	4328	0.12
chr11_70404879_70405056	0.27	Pelp1	proline, glutamic acid and leucine rich protein 1	5061	0.09
chr8_105796118_105796294	0.27	Ranbp10	RAN binding protein 10	30999	0.07
chr12_112111213_112111675	0.27	Aspg	asparaginase	1496	0.24
chr13_63256313_63256480	0.27	Gm47603	predicted gene, 47603	832	0.41
chr15_64155705_64155901	0.27	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	31997	0.18
chrX_85793507_85793673	0.27	Gm6964	predicted gene 6964	530	0.68
chrX_13062821_13063132	0.27	Usp9x	ubiquitin specific peptidase 9, X chromosome	8522	0.19
chr8_83747944_83748146	0.26	Gm45778	predicted gene 45778	1459	0.29
chr15_83524040_83524213	0.26	Bik	BCL2-interacting killer	2736	0.16
chr17_42924837_42925015	0.26	Cd2ap	CD2-associated protein	48261	0.17
chr16_26695984_26696378	0.26	Il1rap	interleukin 1 receptor accessory protein	26253	0.23
chr17_56332362_56332517	0.26	Kdm4b	lysine (K)-specific demethylase 4B	6348	0.12
chr11_74869463_74869647	0.26	Sgsm2	small G protein signaling modulator 2	463	0.64
chr7_130248786_130248946	0.26	Fgfr2	fibroblast growth factor receptor 2	12991	0.27
chr13_74502209_74502494	0.26	Gm49763	predicted gene, 49763	8208	0.1
chr11_112810518_112810820	0.26	Gm11681	predicted gene 11681	11661	0.18
chr5_112134275_112134433	0.26	1700016B01Rik	RIKEN cDNA 1700016B01 gene	21883	0.18
chr19_3685828_3686010	0.26	Lrp5	low density lipoprotein receptor-related protein 5	637	0.59
chr8_122003719_122003880	0.26	Banp	BTG3 associated nuclear protein	2952	0.19
chr11_5741148_5741583	0.26	Urgcp	upregulator of cell proliferation	215	0.9
chr18_81199291_81199673	0.25	4930594M17Rik	RIKEN cDNA 4930594M17 gene	36584	0.17
chr5_125127560_125127724	0.25	Ncor2	nuclear receptor co-repressor 2	2742	0.29
chr7_107633306_107633481	0.25	5330417H12Rik	RIKEN cDNA 5330417H12 gene	8232	0.16
chr16_21549898_21550055	0.25	Vps8	VPS8 CORVET complex subunit	13091	0.25
chr19_16498717_16499020	0.25	Gm8222	predicted gene 8222	7804	0.21
chr8_46332765_46332934	0.25	Gm45255	predicted gene 45255	19048	0.11
chrX_102478577_102478728	0.24	Hdac8	histone deacetylase 8	26089	0.19
chr5_117166861_117167023	0.24	n-R5s174	nuclear encoded rRNA 5S 174	29613	0.12
chr11_62568400_62568605	0.24	Gm12280	predicted gene 12280	2119	0.14
chr12_71370184_71370345	0.24	1700083H02Rik	RIKEN cDNA 1700083H02 gene	13944	0.15
chr17_31930278_31930580	0.24	Gm30571	predicted gene, 30571	17763	0.12
chr7_99141254_99141466	0.24	Uvrag	UV radiation resistance associated gene	219	0.5
chr7_50868844_50869021	0.24	Gm9343	predicted gene 9343	74222	0.09
chr5_53957420_53957607	0.24	Gm43266	predicted gene 43266	39069	0.14
chr4_45499631_45499795	0.24	Gm22518	predicted gene, 22518	839	0.56
chr5_32735922_32736077	0.24	Gm43695	predicted gene 43695	3335	0.14
chr3_94310992_94311165	0.24	Them4	thioesterase superfamily member 4	942	0.35
chr5_130761960_130762123	0.24	Gm23761	predicted gene, 23761	20660	0.24
chr1_155886750_155887199	0.24	Cep350	centrosomal protein 350	960	0.44
chr14_65100574_65100746	0.24	Extl3	exostosin-like glycosyltransferase 3	2554	0.29
chr17_79904674_79904846	0.24	Atl2	atlastin GTPase 2	8637	0.18
chr5_92773632_92773840	0.24	Mir1961	microRNA 1961	14826	0.18
chr16_21642073_21642273	0.24	Vps8	VPS8 CORVET complex subunit	14542	0.21
chr4_134931334_134931504	0.23	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	409	0.81
chr11_45145769_45145947	0.23	Gm12160	predicted gene 12160	15085	0.2
chr13_33935183_33935334	0.23	1110046J04Rik	RIKEN cDNA 1110046J04 gene	309	0.67
chr16_28989883_28990229	0.23	Gm8253	predicted gene 8253	38701	0.19
chr2_59193239_59193408	0.23	Pkp4	plakophilin 4	7451	0.22
chr4_82621551_82621752	0.23	Gm11268	predicted gene 11268	20749	0.19
chr9_70672050_70672218	0.23	Adam10	a disintegrin and metallopeptidase domain 10	6863	0.18
chr5_114772969_114773120	0.23	Git2	GIT ArfGAP 2	390	0.68
chr3_18080789_18080940	0.23	Gm23726	predicted gene, 23726	11538	0.2
chr4_149887083_149887262	0.23	Gm13070	predicted gene 13070	16834	0.13
chr2_93823530_93823821	0.23	Ext2	exostosin glycosyltransferase 2	1107	0.46
chr8_115089778_115090403	0.23	Gm22556	predicted gene, 22556	37177	0.23
chr9_48592438_48592815	0.23	Nnmt	nicotinamide N-methyltransferase	4749	0.26
chr1_40221808_40222119	0.22	Il1r1	interleukin 1 receptor, type I	3117	0.26
chr15_27800508_27800681	0.22	Trio	triple functional domain (PTPRF interacting)	11956	0.22
chr3_57435613_57435790	0.22	Tm4sf4	transmembrane 4 superfamily member 4	10387	0.22
chr7_48883645_48884044	0.22	E2f8	E2F transcription factor 8	2248	0.2
chr4_149098057_149098222	0.22	Pex14	peroxisomal biogenesis factor 14	1670	0.22

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Tgif2_Tgif2lx1_Tgif2lx2

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:2000138	positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1	0.3	GO:0006868	glutamine transport(GO:0006868)
0.1	0.3	GO:1904393	regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1	0.2	GO:0034499	late endosome to Golgi transport(GO:0034499)
0.1	0.1	GO:0060847	endothelial cell fate specification(GO:0060847)
0.0	0.1	GO:1902809	regulation of skeletal muscle fiber differentiation(GO:1902809)
0.0	0.2	GO:1903626	positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.1	GO:0090038	negative regulation of protein kinase C signaling(GO:0090038)
0.0	0.1	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0034421	post-translational protein acetylation(GO:0034421)
0.0	0.2	GO:0038161	prolactin signaling pathway(GO:0038161)
0.0	0.1	GO:2000860	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0036066	protein O-linked fucosylation(GO:0036066)
0.0	0.1	GO:0036493	positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0	0.3	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0010728	regulation of hydrogen peroxide biosynthetic process(GO:0010728)
0.0	0.2	GO:0006104	succinyl-CoA metabolic process(GO:0006104)
0.0	0.1	GO:0060339	negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.0	0.2	GO:0052805	histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0	0.1	GO:1901509	regulation of endothelial tube morphogenesis(GO:1901509)
0.0	0.1	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.2	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0	0.1	GO:0035279	mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0	0.1	GO:2000659	regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0	0.1	GO:0021847	ventricular zone neuroblast division(GO:0021847)
0.0	0.0	GO:1903898	negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0	0.1	GO:0051126	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316) negative regulation of actin nucleation(GO:0051126)
0.0	0.1	GO:0002525	acute inflammatory response to non-antigenic stimulus(GO:0002525)
0.0	0.1	GO:0070669	response to interleukin-2(GO:0070669)
0.0	0.2	GO:0010890	positive regulation of sequestering of triglyceride(GO:0010890)
0.0	0.1	GO:0006114	glycerol biosynthetic process(GO:0006114)
0.0	0.1	GO:0061635	regulation of protein complex stability(GO:0061635)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.1	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.3	GO:0072600	establishment of protein localization to Golgi(GO:0072600)
0.0	0.1	GO:0097360	chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.0	0.1	GO:1902744	negative regulation of lamellipodium organization(GO:1902744)
0.0	0.2	GO:0072364	regulation of cellular ketone metabolic process by regulation of transcription from RNA polymerase II promoter(GO:0072364)
0.0	0.0	GO:1901740	negative regulation of myoblast fusion(GO:1901740)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.1	GO:0010694	positive regulation of alkaline phosphatase activity(GO:0010694)
0.0	0.1	GO:0051344	negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0	0.3	GO:0046599	regulation of centriole replication(GO:0046599)
0.0	0.2	GO:0042904	9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0	0.1	GO:0032911	negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0	0.2	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.1	GO:0070779	D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0	0.3	GO:0031998	regulation of fatty acid beta-oxidation(GO:0031998)
0.0	0.1	GO:0050923	regulation of negative chemotaxis(GO:0050923)
0.0	0.0	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0035434	copper ion transmembrane transport(GO:0035434)
0.0	0.3	GO:0007095	mitotic G2 DNA damage checkpoint(GO:0007095)
0.0	0.1	GO:0032020	ISG15-protein conjugation(GO:0032020)
0.0	0.1	GO:0032484	Ral protein signal transduction(GO:0032484)
0.0	0.0	GO:0035771	interleukin-4-mediated signaling pathway(GO:0035771)
0.0	0.1	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.1	GO:0006990	positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0	0.0	GO:2001016	positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0	0.1	GO:0071673	regulation of smooth muscle cell chemotaxis(GO:0071671) positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0	0.1	GO:0006681	galactosylceramide metabolic process(GO:0006681)
0.0	0.1	GO:0003032	detection of oxygen(GO:0003032)
0.0	0.1	GO:0090286	cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0	0.1	GO:2000468	regulation of peroxidase activity(GO:2000468)
0.0	0.1	GO:0042117	monocyte activation(GO:0042117)
0.0	0.1	GO:0051771	negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771)
0.0	0.1	GO:0034498	early endosome to Golgi transport(GO:0034498)
0.0	0.1	GO:0032049	cardiolipin biosynthetic process(GO:0032049)
0.0	0.1	GO:0021914	negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0	0.0	GO:0051342	regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)
0.0	0.2	GO:1901339	regulation of store-operated calcium channel activity(GO:1901339)
0.0	0.2	GO:0006183	GTP biosynthetic process(GO:0006183)
0.0	0.1	GO:0032792	negative regulation of CREB transcription factor activity(GO:0032792)
0.0	0.1	GO:0014744	positive regulation of muscle adaptation(GO:0014744)
0.0	0.1	GO:0001555	oocyte growth(GO:0001555)
0.0	0.0	GO:0006655	phosphatidylglycerol biosynthetic process(GO:0006655)
0.0	0.0	GO:0060486	Clara cell differentiation(GO:0060486)
0.0	0.1	GO:0009449	gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.0	0.1	GO:0016561	protein import into peroxisome matrix, translocation(GO:0016561)
0.0	0.1	GO:0033600	negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.0	0.0	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.0	0.1	GO:1902897	regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0	0.3	GO:0043567	regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0	0.0	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.0	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.1	GO:0038063	collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0	0.1	GO:0036484	trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491)
0.0	0.0	GO:0038171	cannabinoid signaling pathway(GO:0038171) endocannabinoid signaling pathway(GO:0071926)
0.0	0.0	GO:0021773	striatal medium spiny neuron differentiation(GO:0021773)
0.0	0.1	GO:0034638	phosphatidylcholine catabolic process(GO:0034638)
0.0	0.0	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.0	GO:0001560	regulation of cell growth by extracellular stimulus(GO:0001560)
0.0	0.0	GO:0019254	carnitine metabolic process, CoA-linked(GO:0019254)
0.0	0.0	GO:0002554	serotonin secretion by platelet(GO:0002554)
0.0	0.1	GO:0006651	diacylglycerol biosynthetic process(GO:0006651)
0.0	0.0	GO:0048549	positive regulation of pinocytosis(GO:0048549)
0.0	0.1	GO:0010991	negative regulation of SMAD protein complex assembly(GO:0010991)
0.0	0.0	GO:0018879	biphenyl metabolic process(GO:0018879)
0.0	0.2	GO:0071157	negative regulation of cell cycle arrest(GO:0071157)
0.0	0.1	GO:0071830	chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0	0.0	GO:0002434	immune complex clearance(GO:0002434)
0.0	0.1	GO:0042997	negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.0	0.0	GO:2000670	positive regulation of dendritic cell apoptotic process(GO:2000670)
0.0	0.0	GO:1903416	response to glycoside(GO:1903416)
0.0	0.1	GO:0045053	protein retention in Golgi apparatus(GO:0045053)
0.0	0.0	GO:0006842	tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0	0.0	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.0	GO:0048208	vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.0	0.0	GO:0032077	positive regulation of deoxyribonuclease activity(GO:0032077)
0.0	0.1	GO:0007296	vitellogenesis(GO:0007296)
0.0	0.1	GO:0034058	endosomal vesicle fusion(GO:0034058)
0.0	0.1	GO:1903551	regulation of extracellular exosome assembly(GO:1903551)
0.0	0.1	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.0	GO:1904526	regulation of microtubule binding(GO:1904526) positive regulation of microtubule binding(GO:1904528)
0.0	0.1	GO:0046618	drug export(GO:0046618)
0.0	0.0	GO:0071873	response to norepinephrine(GO:0071873)
0.0	0.0	GO:2000418	positive regulation of eosinophil migration(GO:2000418)
0.0	0.0	GO:0015886	heme transport(GO:0015886)
0.0	0.1	GO:0048170	positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0	0.1	GO:0034392	negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0	0.1	GO:0031936	negative regulation of chromatin silencing(GO:0031936)
0.0	0.0	GO:1990314	cellular response to insulin-like growth factor stimulus(GO:1990314)
0.0	0.0	GO:0022007	neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.0	0.1	GO:2001256	regulation of store-operated calcium entry(GO:2001256)
0.0	0.1	GO:0015825	L-serine transport(GO:0015825)
0.0	0.1	GO:0060718	chorionic trophoblast cell differentiation(GO:0060718)
0.0	0.0	GO:0006768	biotin metabolic process(GO:0006768)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:0021698	cerebellar cortex structural organization(GO:0021698)
0.0	0.1	GO:2001224	positive regulation of neuron migration(GO:2001224)
0.0	0.1	GO:0046543	development of secondary female sexual characteristics(GO:0046543)
0.0	0.0	GO:0048254	snoRNA localization(GO:0048254)
0.0	0.0	GO:1900748	positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0	0.1	GO:0000244	spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:0001302	replicative cell aging(GO:0001302)
0.0	0.1	GO:0061154	endothelial tube morphogenesis(GO:0061154)
0.0	0.0	GO:0023021	termination of signal transduction(GO:0023021)
0.0	0.0	GO:0002432	granuloma formation(GO:0002432)
0.0	0.0	GO:0032474	otolith morphogenesis(GO:0032474)
0.0	0.1	GO:0030948	negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0	0.0	GO:0060633	negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) negative regulation of DNA-templated transcription, initiation(GO:2000143)
0.0	0.0	GO:1901656	glycoside transport(GO:1901656)
0.0	0.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.0	GO:0060468	prevention of polyspermy(GO:0060468)
0.0	0.1	GO:0015884	folic acid transport(GO:0015884)
0.0	0.2	GO:0030212	hyaluronan metabolic process(GO:0030212)
0.0	0.1	GO:0000160	phosphorelay signal transduction system(GO:0000160)
0.0	0.0	GO:0045074	interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0	0.0	GO:0075136	response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0005638	lamin filament(GO:0005638)
0.0	0.2	GO:0016942	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0009331	glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0	0.2	GO:0071014	post-mRNA release spliceosomal complex(GO:0071014)
0.0	0.1	GO:0071001	U4/U6 snRNP(GO:0071001)
0.0	0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.1	GO:0020016	ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0	0.1	GO:0034666	integrin alpha2-beta1 complex(GO:0034666)
0.0	0.2	GO:0005767	secondary lysosome(GO:0005767)
0.0	0.1	GO:0036488	CHOP-C/EBP complex(GO:0036488)
0.0	0.1	GO:0071203	WASH complex(GO:0071203)
0.0	0.1	GO:0030121	AP-1 adaptor complex(GO:0030121)
0.0	0.1	GO:0098642	collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0	0.1	GO:0030981	cortical microtubule cytoskeleton(GO:0030981)
0.0	0.1	GO:0043259	laminin-10 complex(GO:0043259)
0.0	0.1	GO:0034992	microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0	0.1	GO:0031390	Ctf18 RFC-like complex(GO:0031390)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.1	GO:0042587	glycogen granule(GO:0042587)
0.0	0.1	GO:0033263	CORVET complex(GO:0033263)
0.0	0.0	GO:0030130	clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0	0.0	GO:0097443	sorting endosome(GO:0097443)
0.0	0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0	0.1	GO:0045252	oxoglutarate dehydrogenase complex(GO:0045252)
0.0	0.0	GO:0031523	Myb complex(GO:0031523)
0.0	0.0	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.0	GO:0071664	catenin-TCF7L2 complex(GO:0071664)
0.0	0.0	GO:0042825	TAP complex(GO:0042825)
0.0	0.1	GO:0008541	proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0	0.2	GO:0031907	peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0	0.2	GO:0031306	intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0	0.1	GO:0002116	semaphorin receptor complex(GO:0002116)
0.0	0.0	GO:1990597	AIP1-IRE1 complex(GO:1990597)
0.0	0.1	GO:0016589	NURF complex(GO:0016589)
0.0	0.1	GO:0030062	mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0	0.2	GO:0030673	axolemma(GO:0030673)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	GO:0031433	telethonin binding(GO:0031433)
0.1	0.3	GO:0015186	L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.1	0.7	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0004591	oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.2	GO:0005131	growth hormone receptor binding(GO:0005131)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.1	GO:0004367	glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.0	0.2	GO:0004673	protein histidine kinase activity(GO:0004673)
0.0	0.2	GO:0018655	3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) thalianol hydroxylase activity(GO:0080014)
0.0	0.1	GO:0015252	hydrogen ion channel activity(GO:0015252)
0.0	0.1	GO:0070698	type I activin receptor binding(GO:0070698)
0.0	0.1	GO:0005168	neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.1	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.1	GO:0004611	phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0	0.1	GO:0008390	testosterone 16-alpha-hydroxylase activity(GO:0008390)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.3	GO:0008432	JUN kinase binding(GO:0008432)
0.0	0.1	GO:0031727	CCR2 chemokine receptor binding(GO:0031727)
0.0	0.2	GO:0043008	ATP-dependent protein binding(GO:0043008)
0.0	0.0	GO:0030621	U4 snRNA binding(GO:0030621)
0.0	0.1	GO:0047035	testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0	0.1	GO:0016716	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.0	0.1	GO:0038064	collagen receptor activity(GO:0038064)
0.0	0.1	GO:0004427	inorganic diphosphatase activity(GO:0004427)
0.0	0.1	GO:0070097	delta-catenin binding(GO:0070097)
0.0	0.1	GO:0019966	interleukin-1 binding(GO:0019966)
0.0	0.1	GO:0005007	fibroblast growth factor-activated receptor activity(GO:0005007)
0.0	0.1	GO:0016841	ammonia-lyase activity(GO:0016841)
0.0	0.1	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.0	0.1	GO:0008526	phosphatidylinositol transporter activity(GO:0008526)
0.0	0.1	GO:0030151	molybdenum ion binding(GO:0030151)
0.0	0.0	GO:0045134	uridine-diphosphatase activity(GO:0045134)
0.0	0.0	GO:0046978	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.1	GO:0016892	endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0	0.0	GO:0060230	lipoprotein lipase activator activity(GO:0060230)
0.0	0.0	GO:1990460	leptin receptor binding(GO:1990460)
0.0	0.1	GO:0008294	calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0	0.0	GO:0019959	interleukin-8 binding(GO:0019959)
0.0	0.1	GO:0045294	alpha-catenin binding(GO:0045294)
0.0	0.1	GO:0035727	lysophosphatidic acid binding(GO:0035727)
0.0	0.1	GO:0004468	lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0	0.1	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.0	0.1	GO:0046912	transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0	0.2	GO:0004622	lysophospholipase activity(GO:0004622)
0.0	0.0	GO:0015137	citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0051022	Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.0	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0	0.1	GO:0004661	protein geranylgeranyltransferase activity(GO:0004661)
0.0	0.0	GO:0080084	RNA polymerase III type 1 promoter DNA binding(GO:0001030) RNA polymerase III type 2 promoter DNA binding(GO:0001031) RNA polymerase III type 3 promoter DNA binding(GO:0001032) 5S rDNA binding(GO:0080084)
0.0	0.1	GO:0004726	non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0	0.0	GO:0004731	purine-nucleoside phosphorylase activity(GO:0004731)
0.0	0.1	GO:0005315	inorganic phosphate transmembrane transporter activity(GO:0005315)
0.0	0.1	GO:0016176	superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0	0.0	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.2	GO:0035259	glucocorticoid receptor binding(GO:0035259)
0.0	0.2	GO:0030215	semaphorin receptor binding(GO:0030215)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0015016	[heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0	0.1	GO:0003689	DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0	0.1	GO:0008046	axon guidance receptor activity(GO:0008046)
0.0	0.0	GO:0004687	myosin light chain kinase activity(GO:0004687)
0.0	0.1	GO:0004301	epoxide hydrolase activity(GO:0004301)
0.0	0.1	GO:0043912	D-lysine oxidase activity(GO:0043912)
0.0	0.1	GO:0016615	malate dehydrogenase activity(GO:0016615)
0.0	0.0	GO:0070053	thrombospondin receptor activity(GO:0070053)
0.0	0.0	GO:0008427	calcium-dependent protein kinase inhibitor activity(GO:0008427)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.0	PID IL8 CXCR1 PATHWAY	IL8- and CXCR1-mediated signaling events
0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.0	PID TCPTP PATHWAY	Signaling events mediated by TCPTP
0.2	PID TCR JNK PATHWAY	JNK signaling in the CD4+ TCR pathway
0.5	PID NCADHERIN PATHWAY	N-cadherin signaling events
0.1	ST IL 13 PATHWAY	Interleukin 13 (IL-13) Pathway
0.0	SIG CD40PATHWAYMAP	Genes related to CD40 signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	REACTOME XENOBIOTICS	Genes involved in Xenobiotics
0.1	0.7	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING	Genes involved in Role of second messengers in netrin-1 signaling
0.0	0.1	REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK	Genes involved in Negative regulation of the PI3K/AKT network
0.0	0.1	REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION	Genes involved in Apoptosis induced DNA fragmentation
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME FGFR2C LIGAND BINDING AND ACTIVATION	Genes involved in FGFR2c ligand binding and activation
0.0	0.2	REACTOME GROWTH HORMONE RECEPTOR SIGNALING	Genes involved in Growth hormone receptor signaling
0.0	0.0	REACTOME SIGNALING BY ERBB2	Genes involved in Signaling by ERBB2
0.0	0.1	REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR	Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0	0.2	REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY	Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0	0.1	REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL	Genes involved in NF-kB is activated and signals survival
0.0	0.2	REACTOME REGULATION OF IFNG SIGNALING	Genes involved in Regulation of IFNG signaling
0.0	0.1	REACTOME ACTIVATION OF CHAPERONES BY ATF6 ALPHA	Genes involved in Activation of Chaperones by ATF6-alpha
0.0	0.2	REACTOME OTHER SEMAPHORIN INTERACTIONS	Genes involved in Other semaphorin interactions
0.0	0.0	REACTOME ARMS MEDIATED ACTIVATION	Genes involved in ARMS-mediated activation
0.0	0.0	REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS	Genes involved in Thrombin signalling through proteinase activated receptors (PARs)