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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Thrb

Z-value: 1.82

Motif logo

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Transcription factors associated with Thrb

Gene Symbol Gene ID Gene Info
Thrb
ENSMUSG00000021779.10 thyroid hormone receptor beta

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr14_17695776_17695955Thrb349690.214039-0.988.9e-04Click!
chr14_17681136_17681362Thrb203530.265627-0.954.1e-03Click!
chr14_17681830_17681997Thrb210170.263428-0.954.2e-03Click!
chr14_17685511_17685778Thrb247480.2507110.944.6e-03Click!
chr14_17915471_17915812Thrb471800.161904-0.945.0e-03Click!

Activity of the Thrb motif across conditions

Conditions sorted by the z-value of the Thrb motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr7_126260333_126260533 1.81 Sbk1
 SH3-binding kinase 1
 11571
 0.11
chr14_25377112_25377271 1.48 Gm26660
 predicted gene, 26660
 1444
 0.44
chr19_4436418_4436609 1.40 A930001C03Rik
 RIKEN cDNA A930001C03 gene
 2490
 0.17
chr19_10901185_10901365 1.37 Prpf19
 pre-mRNA processing factor 19
 993
 0.37
chr4_142069494_142069660 1.31 Tmem51os1
 Tmem51 opposite strand 1
 14395
 0.13
chr3_98288408_98289120 1.31 Gm43189
 predicted gene 43189
 1776
 0.28
chr16_31994081_31994256 1.29 Hmgb1-ps6
 high mobility group box 1, pseudogene 6
 2300
 0.13
chr19_5763306_5763457 1.29 Scyl1
 SCY1-like 1 (S. cerevisiae)
 1605
 0.16
chr10_70099167_70099342 1.28 Ccdc6
 coiled-coil domain containing 6
 2133
 0.41
chr1_86600398_86600549 1.27 Cops7b
 COP9 signalosome subunit 7B
 3733
 0.15
chr12_111514450_111514666 1.26 Gm40578
 predicted gene, 40578
 13718
 0.1
chr4_148215189_148215340 1.25 Disp3
 dispatched RND transporter family member 3
 45487
 0.08
chr6_112939448_112939605 1.22 Srgap3
 SLIT-ROBO Rho GTPase activating protein 3
 7228
 0.15
chr2_36244831_36245001 1.17 Ptgs1
 prostaglandin-endoperoxide synthase 1
 2441
 0.18
chr8_114982881_114983044 1.15 Gm22556
 predicted gene, 22556
 69951
 0.14
chr11_82015046_82015230 1.13 Gm31522
 predicted gene, 31522
 4829
 0.14
chr12_98573684_98573967 1.06 Kcnk10
 potassium channel, subfamily K, member 10
 887
 0.51
chr2_151943059_151943241 1.04 Gm14154
 predicted gene 14154
 7491
 0.14
chr3_83850904_83851066 1.03 Tlr2
 toll-like receptor 2
 9218
 0.2
chr19_23110526_23110678 1.02 2410080I02Rik
 RIKEN cDNA 2410080I02 gene
 24298
 0.14
chr14_45315776_45315957 1.02 Ero1l
 ERO1-like (S. cerevisiae)
 2706
 0.19
chr1_191224850_191225043 1.01 D730003I15Rik
 RIKEN cDNA D730003I15 gene
 472
 0.74
chr17_13425168_13425333 0.99 Rnu6
 U6 small nuclear RNA
 6889
 0.12
chr11_82845122_82845302 0.99 Rffl
 ring finger and FYVE like domain containing protein
 880
 0.45
chr13_56648096_56648259 0.98 Tgfbi
 transforming growth factor, beta induced
 16964
 0.19
chr2_104130173_104130336 0.98 A930018P22Rik
 RIKEN cDNA A930018P22 gene
 7485
 0.14
chr18_24652431_24652590 0.97 Mocos
 molybdenum cofactor sulfurase
 1181
 0.43
chr17_7387699_7387859 0.97 Unc93a2
 unc-93 homolog A2
 2315
 0.22
chr6_121890040_121890777 0.95 Mug1
 murinoglobulin 1
 4831
 0.21
chr5_9056138_9056296 0.95 Gm40264
 predicted gene, 40264
 21093
 0.14
chr5_32141078_32141248 0.92 Fosl2
 fos-like antigen 2
 4990
 0.17
chr10_61929391_61929572 0.91 Gm5750
 predicted gene 5750
 30143
 0.16
chr15_102091806_102092001 0.89 Eif4b
 eukaryotic translation initiation factor 4B
 2661
 0.17
chr3_98245800_98245972 0.87 Gm42821
 predicted gene 42821
 2713
 0.21
chr5_121856848_121857131 0.86 Pheta1
 PH domain containing endocytic trafficking adaptor 1
 7984
 0.11
chr14_26450001_26450182 0.86 Slmap
 sarcolemma associated protein
 7201
 0.16
chr3_10294464_10294624 0.83 Fabp12
 fatty acid binding protein 12
 6630
 0.1
chr3_36475756_36475914 0.82 Anxa5
 annexin A5
 59
 0.49
chr9_22420603_22420765 0.81 9530077C05Rik
 RIKEN cDNA 9530077C05 gene
 9045
 0.11
chr1_24693656_24693810 0.81 Lmbrd1
 LMBR1 domain containing 1
 14807
 0.17
chr7_132578212_132578403 0.81 Oat
 ornithine aminotransferase
 1909
 0.28
chr1_60824712_60825126 0.81 Gm11581
 predicted gene 11581
 15803
 0.12
chr15_99837964_99838156 0.80 Lima1
 LIM domain and actin binding 1
 17917
 0.08
chr11_109347489_109347695 0.78 1700096J18Rik
 RIKEN cDNA 1700096J18 gene
 753
 0.57
chr1_161750733_161750915 0.78 Gm5049
 predicted gene 5049
 4768
 0.17
chr9_57652474_57652625 0.78 Csk
 c-src tyrosine kinase
 922
 0.44
chr11_119056313_119056482 0.77 Cbx8
 chromobox 8
 15428
 0.14
chr3_108046974_108047188 0.77 Gstm4
 glutathione S-transferase, mu 4
 2187
 0.13
chr3_146846305_146846456 0.76 Ttll7
 tubulin tyrosine ligase-like family, member 7
 5987
 0.18
chr8_106619727_106619898 0.75 Cdh1
 cadherin 1
 15669
 0.17
chr15_97029707_97029895 0.74 Slc38a4
 solute carrier family 38, member 4
 1410
 0.55
chr11_62934808_62934982 0.73 Tvp23bos
 trans-golgi network vesicle protein 23B, opposite strand
 13303
 0.13
chr6_70814000_70814168 0.73 Rpia
 ribose 5-phosphate isomerase A
 21852
 0.13
chr9_113738969_113739195 0.73 Clasp2
 CLIP associating protein 2
 2391
 0.3
chr18_61374503_61374706 0.72 Gm25301
 predicted gene, 25301
 23209
 0.12
chr12_24630346_24630510 0.70 Gm6969
 predicted pseudogene 6969
 8582
 0.16
chr14_17916764_17916922 0.70 Thrb
 thyroid hormone receptor beta
 45978
 0.16
chr6_134043668_134043819 0.70 Etv6
 ets variant 6
 7774
 0.2
chr15_99820031_99820226 0.70 Lima1
 LIM domain and actin binding 1
 15
 0.93
chr13_34739256_34739451 0.69 Fam50b
 family with sequence similarity 50, member B
 259
 0.88
chr8_36202101_36202262 0.69 Gm35520
 predicted gene, 35520
 13809
 0.15
chr6_128498166_128498338 0.68 Pzp
 PZP, alpha-2-macroglobulin like
 3029
 0.13
chr15_75314541_75314705 0.68 Gm3454
 predicted gene 3454
 341
 0.79
chr4_106988955_106989270 0.68 Ssbp3
 single-stranded DNA binding protein 3
 22686
 0.15
chr12_85473320_85473671 0.67 Fos
 FBJ osteosarcoma oncogene
 395
 0.83
chr9_70234563_70234714 0.67 Myo1e
 myosin IE
 27270
 0.19
chr8_70657841_70658013 0.67 Pgpep1
 pyroglutamyl-peptidase I
 489
 0.61
chr9_118958897_118959171 0.67 Ctdspl
 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
 29167
 0.13
chr11_60935743_60935912 0.66 Map2k3
 mitogen-activated protein kinase kinase 3
 3761
 0.16
chr14_63479379_63479556 0.66 Gm47074
 predicted gene, 47074
 4091
 0.16
chr11_71012867_71013036 0.66 Derl2
 Der1-like domain family, member 2
 6261
 0.09
chr14_18678485_18678659 0.66 Ube2e2
 ubiquitin-conjugating enzyme E2E 2
 13422
 0.25
chr4_133804499_133804683 0.65 Gm25270
 predicted gene, 25270
 6872
 0.14
chr7_81189147_81189298 0.65 Gm44968
 predicted gene 44968
 15788
 0.13
chr12_77216600_77216773 0.65 Fut8
 fucosyltransferase 8
 21439
 0.19
chr15_31545253_31545412 0.65 Marchf6
 membrane associated ring-CH-type finger 6
 14279
 0.12
chr9_107593234_107593397 0.64 Ifrd2
 interferon-related developmental regulator 2
 688
 0.28
chr1_131957507_131957689 0.64 Gm29103
 predicted gene 29103
 5356
 0.12
chr7_19744671_19744853 0.64 Nectin2
 nectin cell adhesion molecule 2
 4771
 0.08
chr7_38197786_38197937 0.63 D530033B14Rik
 RIKEN cDNA D530033B14 gene
 1404
 0.32
chr5_24956925_24957102 0.63 1500035N22Rik
 RIKEN cDNA 1500035N22 gene
 28829
 0.14
chr15_99911968_99912127 0.62 Gm20564
 predicted gene, 20564
 3853
 0.1
chr11_75596908_75597126 0.62 4931413K12Rik
 RIKEN cDNA 4931413K12 gene
 2246
 0.16
chr12_98860402_98860781 0.61 A930040O22Rik
 RIKEN cDNA A930040O22 gene
 28778
 0.12
chr6_122161223_122161580 0.61 Mug-ps1
 murinoglobulin, pseudogene 1
 14614
 0.16
chr1_186703631_186703811 0.61 Tgfb2
 transforming growth factor, beta 2
 612
 0.62
chr15_85808535_85808715 0.61 Cdpf1
 cysteine rich, DPF motif domain containing 1
 2465
 0.2
chr8_103180795_103180954 0.60 Gm45391
 predicted gene 45391
 35928
 0.21
chr19_58439431_58439649 0.60 Gfra1
 glial cell line derived neurotrophic factor family receptor alpha 1
 14926
 0.22
chr13_43232609_43232789 0.60 Tbc1d7
 TBC1 domain family, member 7
 61198
 0.1
chr12_108856815_108857551 0.60 Gm22079
 predicted gene, 22079
 5486
 0.1
chr4_150065927_150066095 0.59 Mir34a
 microRNA 34a
 2443
 0.16
chr16_47171920_47172088 0.59 Gm18169
 predicted gene, 18169
 40366
 0.21
chr13_41239510_41239683 0.59 Gm32063
 predicted gene, 32063
 3251
 0.15
chr2_34983172_34983323 0.59 Hc
 hemolytic complement
 10089
 0.12
chr6_128483626_128483790 0.58 Pzp
 PZP, alpha-2-macroglobulin like
 4147
 0.1
chr8_126636622_126636807 0.58 Irf2bp2
 interferon regulatory factor 2 binding protein 2
 42728
 0.16
chr10_80973010_80973161 0.57 Gm3828
 predicted gene 3828
 18375
 0.08
chr16_4886806_4886964 0.57 Mgrn1
 mahogunin, ring finger 1
 499
 0.69
chr12_12999123_12999274 0.57 Gm35208
 predicted gene, 35208
 11881
 0.16
chr18_36738903_36739066 0.57 Tmco6
 transmembrane and coiled-coil domains 6
 3817
 0.09
chr7_79358682_79358833 0.56 Rlbp1
 retinaldehyde binding protein 1
 18946
 0.13
chr19_38125391_38125548 0.56 Rbp4
 retinol binding protein 4, plasma
 188
 0.93
chr15_66932473_66932630 0.55 Ndrg1
 N-myc downstream regulated gene 1
 1918
 0.28
chr11_49996483_49996658 0.55 Rnf130
 ring finger protein 130
 28776
 0.14
chr10_120752084_120752244 0.55 Gm10743
 predicted gene 10743
 3831
 0.15
chr13_98684591_98684906 0.55 Tmem171
 transmembrane protein 171
 10020
 0.14
chr6_88913100_88913275 0.54 Tpra1
 transmembrane protein, adipocyte asscociated 1
 2588
 0.17
chr13_69582483_69582651 0.54 Srd5a1
 steroid 5 alpha-reductase 1
 12262
 0.12
chr15_90992378_90992671 0.54 Kif21a
 kinesin family member 21A
 26122
 0.16
chr2_6595830_6596024 0.53 Celf2
 CUGBP, Elav-like family member 2
 3127
 0.35
chr3_101835406_101835600 0.53 Mab21l3
 mab-21-like 3
 720
 0.72
chr19_36692056_36692224 0.52 Hectd2os
 Hectd2, opposite strand
 2661
 0.32
chr5_139612620_139612791 0.52 Uncx
 UNC homeobox
 68807
 0.08
chr13_52153674_52153844 0.52 Gm48199
 predicted gene, 48199
 26652
 0.19
chr7_99641322_99641487 0.52 Gm25409
 predicted gene, 25409
 12414
 0.09
chr8_103538740_103538926 0.52 Gm45277
 predicted gene 45277
 24790
 0.23
chr9_110781917_110782081 0.51 Myl3
 myosin, light polypeptide 3
 13564
 0.1
chr8_12719084_12719404 0.51 Gm15348
 predicted gene 15348
 117
 0.96
chr10_77118451_77118858 0.51 Col18a1
 collagen, type XVIII, alpha 1
 4708
 0.2
chr18_75307577_75307805 0.51 2010010A06Rik
 RIKEN cDNA 2010010A06 gene
 10362
 0.22
chr2_169694792_169694990 0.51 Tshz2
 teashirt zinc finger family member 2
 61215
 0.13
chr2_26600848_26601015 0.51 Agpat2
 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
 2785
 0.12
chr1_71705120_71705280 0.51 Gm5829
 predicted gene 5829
 4855
 0.2
chr11_24789291_24789442 0.50 Gm10466
 predicted gene 10466
 58644
 0.14
chr2_168005469_168005791 0.50 Gm14236
 predicted gene 14236
 4899
 0.17
chr2_162986609_162986768 0.50 Sgk2
 serum/glucocorticoid regulated kinase 2
 642
 0.6
chr10_115809219_115809409 0.50 Tspan8
 tetraspanin 8
 7518
 0.27
chr4_152177650_152177825 0.50 Acot7
 acyl-CoA thioesterase 7
 397
 0.77
chr9_54560284_54560443 0.50 Cib2
 calcium and integrin binding family member 2
 145
 0.95
chr1_191154426_191154595 0.50 Fam71a
 family with sequence similarity 71, member A
 10307
 0.13
chr17_28290145_28290326 0.50 Ppard
 peroxisome proliferator activator receptor delta
 3011
 0.15
chr10_80928616_80928783 0.50 Gadd45b
 growth arrest and DNA-damage-inducible 45 beta
 1374
 0.25
chr6_86395136_86395301 0.49 Pcyox1
 prenylcysteine oxidase 1
 1408
 0.24
chr13_73723026_73723388 0.48 Slc12a7
 solute carrier family 12, member 7
 9887
 0.15
chr4_34966679_34966979 0.48 Gm12364
 predicted gene 12364
 4609
 0.19
chr16_13240471_13240636 0.48 Mrtfb
 myocardin related transcription factor B
 15928
 0.25
chr2_118554450_118554815 0.48 Bmf
 BCL2 modifying factor
 4945
 0.18
chr11_58801906_58802080 0.47 Fam183b
 family with sequence similarity 183, member B
 33
 0.94
chr1_151496001_151496317 0.47 Gm36527
 predicted gene, 36527
 3426
 0.15
chr6_39286782_39286965 0.47 Gm26008
 predicted gene, 26008
 20931
 0.15
chr13_5832208_5832483 0.46 Gm26043
 predicted gene, 26043
 10487
 0.17
chr6_71204222_71204852 0.46 Fabp1
 fatty acid binding protein 1, liver
 4710
 0.14
chr16_95432244_95432403 0.46 Erg
 ETS transcription factor
 26922
 0.22
chr14_54476038_54476201 0.46 Rem2
 rad and gem related GTP binding protein 2
 19
 0.95
chr17_13662964_13663132 0.46 2700054A10Rik
 RIKEN cDNA 2700054A10 gene
 5843
 0.16
chr8_116184614_116184784 0.46 4930422C21Rik
 RIKEN cDNA 4930422C21 gene
 2670
 0.42
chr4_133028994_133029156 0.46 Ahdc1
 AT hook, DNA binding motif, containing 1
 10418
 0.18
chr1_71648273_71648424 0.46 Apol7d
 apolipoprotein L 7d
 4489
 0.21
chr10_117082015_117082177 0.46 Cct2
 chaperonin containing Tcp1, subunit 2 (beta)
 18282
 0.13
chr7_115825357_115825510 0.45 Sox6
 SRY (sex determining region Y)-box 6
 723
 0.79
chr10_115780280_115780436 0.45 Tspan8
 tetraspanin 8
 36474
 0.2
chr3_104670184_104670346 0.45 Gm29560
 predicted gene 29560
 255
 0.84
chr8_47991010_47991194 0.45 Wwc2
 WW, C2 and coiled-coil domain containing 2
 178
 0.95
chr10_98915744_98915895 0.45 Atp2b1
 ATPase, Ca++ transporting, plasma membrane 1
 347
 0.92
chr12_111956283_111956452 0.44 Gm36757
 predicted gene, 36757
 5850
 0.11
chr18_47219464_47219645 0.44 Sema6a
 sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
 61641
 0.09
chr2_164563319_164563487 0.44 Wfdc2
 WAP four-disulfide core domain 2
 384
 0.69
chr11_109485510_109486095 0.44 Arsg
 arylsulfatase G
 196
 0.91
chr12_28579239_28579390 0.44 Allc
 allantoicase
 3201
 0.2
chr6_122249737_122249965 0.44 Mug-ps1
 murinoglobulin, pseudogene 1
 20791
 0.13
chr8_89364350_89364531 0.44 Gm5356
 predicted pseudogene 5356
 176880
 0.03
chr18_61909022_61909179 0.43 Ablim3
 actin binding LIM protein family, member 3
 2723
 0.27
chr19_32476509_32476692 0.43 Minpp1
 multiple inositol polyphosphate histidine phosphatase 1
 9169
 0.14
chr1_57989000_57989391 0.43 Sgo2a
 shugoshin 2A
 6776
 0.19
chr2_77113165_77113335 0.42 Gm44360
 predicted gene, 44360
 38898
 0.16
chr15_11394606_11394765 0.42 Tars
 threonyl-tRNA synthetase
 2415
 0.37
chr16_76349002_76349359 0.42 Nrip1
 nuclear receptor interacting protein 1
 23857
 0.18
chr3_117905348_117905499 0.41 Gm4321
 predicted gene 4321
 16409
 0.2
chr2_21211497_21211673 0.41 Thnsl1
 threonine synthase-like 1 (bacterial)
 5798
 0.17
chr4_148651109_148651502 0.41 Gm572
 predicted gene 572
 7988
 0.14
chr6_99145207_99145385 0.41 Foxp1
 forkhead box P1
 17722
 0.26
chr7_126475278_126475550 0.41 Sh2b1
 SH2B adaptor protein 1
 10
 0.95
chr6_81944489_81944663 0.40 Gcfc2
 GC-rich sequence DNA binding factor 2
 1927
 0.23
chr1_127459100_127459460 0.40 Tmem163
 transmembrane protein 163
 41064
 0.15
chr11_63046542_63046708 0.40 Tekt3
 tektin 3
 15029
 0.18
chr18_60738849_60739016 0.40 Ndst1
 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
 5782
 0.16
chr15_25714163_25714331 0.40 Myo10
 myosin X
 376
 0.88
chr13_37857409_37857582 0.40 Rreb1
 ras responsive element binding protein 1
 439
 0.85
chr1_174959965_174960140 0.39 Grem2
 gremlin 2, DAN family BMP antagonist
 38233
 0.21
chr9_118101918_118102083 0.39 Azi2
 5-azacytidine induced gene 2
 42944
 0.13
chr3_104638838_104638989 0.38 Slc16a1
 solute carrier family 16 (monocarboxylic acid transporters), member 1
 245
 0.84
chr2_32248839_32249007 0.38 Pomt1
 protein-O-mannosyltransferase 1
 260
 0.81
chr6_72227116_72227283 0.38 Atoh8
 atonal bHLH transcription factor 8
 7338
 0.17
chr11_62487069_62487231 0.38 Gm12278
 predicted gene 12278
 4353
 0.13
chr8_116367840_116368103 0.38 1700018P08Rik
 RIKEN cDNA 1700018P08 gene
 10910
 0.29
chr8_70104635_70104800 0.38 Mir7066
 microRNA 7066
 2131
 0.15
chr15_34527692_34527846 0.37 Pop1
 processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
 1624
 0.25
chr5_74874877_74875112 0.37 Gm17906
 predicted gene, 17906
 8341
 0.22
chr1_165629214_165629365 0.37 Mpzl1
 myelin protein zero-like 1
 4797
 0.13
chr14_70330142_70330488 0.37 Slc39a14
 solute carrier family 39 (zinc transporter), member 14
 1203
 0.35
chr17_46016022_46016192 0.37 Vegfa
 vascular endothelial growth factor A
 5265
 0.19
chr1_73987938_73988111 0.37 Tns1
 tensin 1
 961
 0.63
chr1_52499794_52500020 0.37 Nab1
 Ngfi-A binding protein 1
 393
 0.8
chr6_116635450_116635635 0.37 Gm44154
 predicted gene, 44154
 5320
 0.11
chr5_115569868_115570025 0.37 Gcn1
 GCN1 activator of EIF2AK4
 4643
 0.11
chr9_83527787_83527959 0.37 Sh3bgrl2
 SH3 domain binding glutamic acid-rich protein like 2
 20454
 0.14
chr12_102297681_102297848 0.37 Rin3
 Ras and Rab interactor 3
 14123
 0.21
chr13_64362005_64362163 0.36 Gm49230
 predicted gene, 49230
 347
 0.71
chr10_75058843_75058998 0.36 Bcr
 BCR activator of RhoGEF and GTPase
 1672
 0.33

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Thrb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0034633 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.2 0.5 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.4 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 0.4 GO:0051891 positive regulation of cardioblast differentiation(GO:0051891)
0.1 0.5 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.1 0.4 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.1 0.3 GO:0075136 response to defenses of other organism involved in symbiotic interaction(GO:0052173) response to host defenses(GO:0052200) response to host(GO:0075136)
0.1 0.4 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.1 0.2 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.1 0.3 GO:0006057 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589)
0.1 0.2 GO:0009233 menaquinone metabolic process(GO:0009233)
0.1 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:0051189 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) molybdopterin cofactor biosynthetic process(GO:0032324) molybdopterin cofactor metabolic process(GO:0043545) prosthetic group metabolic process(GO:0051189)
0.1 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.1 0.5 GO:0071318 cellular response to ATP(GO:0071318)
0.1 0.3 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997)
0.1 0.1 GO:0002434 immune complex clearance(GO:0002434)
0.1 0.4 GO:1901317 regulation of sperm motility(GO:1901317)
0.1 0.2 GO:2000409 positive regulation of T cell extravasation(GO:2000409)
0.1 0.4 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.5 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.1 0.2 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.4 GO:1901660 calcium ion export(GO:1901660)
0.1 0.2 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0051541 elastin metabolic process(GO:0051541)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.2 GO:0052428 negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.1 GO:0015744 succinate transport(GO:0015744)
0.0 0.3 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.5 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.1 GO:1902564 negative regulation of neutrophil activation(GO:1902564)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0001757 somite specification(GO:0001757)
0.0 0.6 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.0 0.3 GO:0030948 negative regulation of vascular endothelial growth factor receptor signaling pathway(GO:0030948)
0.0 0.0 GO:0003330 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.1 GO:1990036 calcium ion import into sarcoplasmic reticulum(GO:1990036)
0.0 0.5 GO:1902895 positive regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902895)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.1 GO:0018916 nitrobenzene metabolic process(GO:0018916)
0.0 0.2 GO:0060059 embryonic retina morphogenesis in camera-type eye(GO:0060059)
0.0 0.2 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
0.0 0.1 GO:0060066 oviduct development(GO:0060066)
0.0 0.0 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.2 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.0 0.2 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:0072015 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.2 GO:1902894 negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0 0.1 GO:0033578 protein glycosylation in Golgi(GO:0033578)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.1 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.1 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0006548 histidine catabolic process(GO:0006548) imidazole-containing compound catabolic process(GO:0052805)
0.0 0.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868)
0.0 0.0 GO:0043634 polyadenylation-dependent ncRNA catabolic process(GO:0043634) nuclear ncRNA surveillance(GO:0071029) nuclear polyadenylation-dependent rRNA catabolic process(GO:0071035) nuclear polyadenylation-dependent ncRNA catabolic process(GO:0071046)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.1 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.0 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0048388 endosomal lumen acidification(GO:0048388)
0.0 0.0 GO:1904339 negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.0 0.2 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.0 GO:2001016 positive regulation of skeletal muscle cell differentiation(GO:2001016)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.8 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 0.1 GO:0060897 neural plate regionalization(GO:0060897)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0051791 medium-chain fatty acid metabolic process(GO:0051791)
0.0 0.1 GO:0009080 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080)
0.0 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.1 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838)
0.0 0.1 GO:2000980 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.0 0.1 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.0 0.1 GO:0003419 growth plate cartilage chondrocyte proliferation(GO:0003419)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.0 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.1 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0010388 cullin deneddylation(GO:0010388)
0.0 0.1 GO:0071673 positive regulation of smooth muscle cell chemotaxis(GO:0071673)
0.0 0.0 GO:0071727 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.3 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.0 GO:0048677 axon extension involved in regeneration(GO:0048677) sprouting of injured axon(GO:0048682)
0.0 0.2 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.0 0.1 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.0 0.1 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.1 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.0 0.1 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.0 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.0 GO:0019064 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.1 GO:1904587 glycoprotein ERAD pathway(GO:0097466) response to glycoprotein(GO:1904587)
0.0 0.0 GO:0065001 specification of axis polarity(GO:0065001)
0.0 0.1 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.0 GO:0001905 activation of membrane attack complex(GO:0001905) regulation of activation of membrane attack complex(GO:0001969)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.0 0.1 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.8 GO:0007566 embryo implantation(GO:0007566)
0.0 0.0 GO:0061038 uterus morphogenesis(GO:0061038)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.2 GO:0051132 NK T cell activation(GO:0051132)
0.0 0.0 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) regulation of serine C-palmitoyltransferase activity(GO:1904220) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.0 GO:0035747 natural killer cell chemotaxis(GO:0035747) regulation of natural killer cell chemotaxis(GO:2000501)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.0 GO:0090296 regulation of mitochondrial DNA replication(GO:0090296)
0.0 0.1 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.1 GO:0034626 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.0 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.0 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 0.0 GO:0006344 maintenance of chromatin silencing(GO:0006344)
0.0 0.1 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.0 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.0 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:0000492 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.0 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:1902668 negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668)
0.0 0.0 GO:0046439 cysteine catabolic process(GO:0009093) L-cysteine catabolic process(GO:0019448) L-cysteine metabolic process(GO:0046439)
0.0 0.0 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.0 GO:0001543 ovarian follicle rupture(GO:0001543)
0.0 0.2 GO:0006883 cellular sodium ion homeostasis(GO:0006883)
0.0 0.0 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.0 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.0 GO:0035907 dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0 0.0 GO:0019087 transformation of host cell by virus(GO:0019087)
0.0 0.0 GO:1901843 positive regulation of high voltage-gated calcium channel activity(GO:1901843)
0.0 0.0 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.2 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.0 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.1 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.2 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.0 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.0 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.0 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.0 GO:0070094 positive regulation of glucagon secretion(GO:0070094)
0.0 0.2 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.0 GO:0006222 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.0 GO:0015755 fructose transport(GO:0015755)
0.0 0.0 GO:0003164 His-Purkinje system development(GO:0003164)
0.0 0.1 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.0 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005927 muscle tendon junction(GO:0005927)
0.1 0.3 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.2 GO:0035355 Toll-like receptor 2-Toll-like receptor 6 protein complex(GO:0035355)
0.1 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.5 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.1 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0044299 C-fiber(GO:0044299)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.2 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.0 0.1 GO:0036195 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.5 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.0 GO:0034679 integrin alpha9-beta1 complex(GO:0034679)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.1 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.0 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.0 GO:0097443 sorting endosome(GO:0097443)
0.0 0.0 GO:0043511 inhibin complex(GO:0043511)
0.0 0.0 GO:0001739 sex chromatin(GO:0001739)
0.0 0.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.0 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.1 GO:0098642 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.4 GO:0030151 molybdenum ion binding(GO:0030151)
0.1 0.4 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.1 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.2 GO:0043888 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.7 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.1 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.0 0.0 GO:0043546 molybdopterin cofactor binding(GO:0043546)
0.0 0.4 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.3 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.6 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.2 GO:0003933 GTP cyclohydrolase activity(GO:0003933)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.1 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182) L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0048156 tau protein binding(GO:0048156)
0.0 0.0 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.3 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0008934 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.3 GO:0030351 inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase activity(GO:0030351) inositol-1,4,5,6-tetrakisphosphate 6-phosphatase activity(GO:0030352) inositol pentakisphosphate phosphatase activity(GO:0052827)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.3 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.0 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.0 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.0 0.1 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.1 GO:0000150 recombinase activity(GO:0000150)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.0 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.1 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.1 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.0 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 0.0 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.0 GO:0018595 mono-butyltin dioxygenase activity(GO:0018586) tri-n-butyltin dioxygenase activity(GO:0018588) di-n-butyltin dioxygenase activity(GO:0018589) methylsilanetriol hydroxylase activity(GO:0018590) methyl tertiary butyl ether 3-monooxygenase activity(GO:0018591) 4-nitrocatechol 4-monooxygenase activity(GO:0018592) 4-chlorophenoxyacetate monooxygenase activity(GO:0018593) tert-butanol 2-monooxygenase activity(GO:0018594) alpha-pinene monooxygenase activity(GO:0018595) dimethylsilanediol hydroxylase activity(GO:0018596) ammonia monooxygenase activity(GO:0018597) hydroxymethylsilanetriol oxidase activity(GO:0018598) 2-hydroxyisobutyrate 3-monooxygenase activity(GO:0018599) alpha-pinene dehydrogenase activity(GO:0018600) bisphenol A hydroxylase B activity(GO:0034559) 2,2-bis(4-hydroxyphenyl)-1-propanol hydroxylase activity(GO:0034562) 9-fluorenone-3,4-dioxygenase activity(GO:0034786) anthracene 9,10-dioxygenase activity(GO:0034816) 2-(methylthio)benzothiazole monooxygenase activity(GO:0034857) 2-hydroxybenzothiazole monooxygenase activity(GO:0034858) benzothiazole monooxygenase activity(GO:0034859) 2,6-dihydroxybenzothiazole monooxygenase activity(GO:0034862) pinacolone 5-monooxygenase activity(GO:0034870) thioacetamide S-oxygenase activity(GO:0034873) thioacetamide S-oxide S-oxygenase activity(GO:0034874) endosulfan monooxygenase I activity(GO:0034888) N-nitrodimethylamine hydroxylase activity(GO:0034893) 4-(1-ethyl-1,4-dimethyl-pentyl)phenol monoxygenase activity(GO:0034897) endosulfan ether monooxygenase activity(GO:0034903) pyrene 4,5-monooxygenase activity(GO:0034925) pyrene 1,2-monooxygenase activity(GO:0034927) 1-hydroxypyrene 6,7-monooxygenase activity(GO:0034928) 1-hydroxypyrene 7,8-monooxygenase activity(GO:0034929) phenylboronic acid monooxygenase activity(GO:0034950) spheroidene monooxygenase activity(GO:0043823)
0.0 0.1 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313) acidic amino acid transmembrane transporter activity(GO:0015172)
0.0 0.2 GO:0001848 complement binding(GO:0001848)
0.0 0.0 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.3 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID LYMPH ANGIOGENESIS PATHWAY VEGFR3 signaling in lymphatic endothelium
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.0 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.0 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.2 PID GMCSF PATHWAY GMCSF-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.6 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.3 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.3 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.3 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.3 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.2 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.1 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.1 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.2 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.0 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)