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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Zbtb49

Z-value: 1.03

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Transcription factors associated with Zbtb49

Gene Symbol	Gene ID	Gene Info
Zbtb49 Ensembl NCBI MGI UniProt	ENSMUSG00000029127.9	Zbtb49

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Zbtb49	chr5_38220383_38220542	5	0.494346	0.84	3.6e-02	Click!
Zbtb49	chr5_38197553_38197712	6165	0.161425	0.47	3.5e-01	Click!
Zbtb49	chr5_38220127_38220304	198	0.563145	0.36	4.8e-01	Click!
Zbtb49	chr5_38219865_38220058	452	0.487467	-0.23	6.6e-01	Click!
Zbtb49	chr5_38205585_38205760	511	0.743866	-0.17	7.5e-01	Click!

Activity of the Zbtb49 motif across conditions

Conditions sorted by the z-value of the Zbtb49 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr16_23964443_23964721	0.87	Bcl6	B cell leukemia/lymphoma 6	7798	0.17
chr1_162250839_162250990	0.71	Mir214	microRNA 214	27546	0.14
chr19_61049084_61049293	0.65	Gm22520	predicted gene, 22520	35643	0.14
chr4_44994303_44994454	0.58	Grhpr	glyoxylate reductase/hydroxypyruvate reductase	12878	0.1
chr3_116329378_116329892	0.56	Gm29151	predicted gene 29151	20468	0.17
chr4_49442637_49442810	0.54	Acnat1	acyl-coenzyme A amino acid N-acyltransferase 1	8411	0.13
chr19_39812543_39812702	0.54	Cyp2c40	cytochrome P450, family 2, subfamily c, polypeptide 40	122	0.97
chr8_105996387_105996711	0.48	Dpep2	dipeptidase 2	126	0.9
chr17_69417917_69418077	0.47	C030034I22Rik	RIKEN cDNA C030034I22 gene	536	0.71
chr11_23124778_23124929	0.45	1700061J23Rik	RIKEN cDNA 1700061J23 gene	27287	0.14
chr15_82442500_82442673	0.43	Gm49421	predicted gene, 49421	894	0.29
chr9_32004053_32004204	0.43	Gm47465	predicted gene, 47465	1332	0.4
chr4_148214912_148215063	0.43	Disp3	dispatched RND transporter family member 3	45764	0.08
chr12_28898892_28899474	0.41	Gm31508	predicted gene, 31508	11046	0.17
chr10_71234987_71235164	0.38	Tfam	transcription factor A, mitochondrial	246	0.89
chr11_46085325_46085478	0.38	Mir8100	microRNA 8100	16869	0.12
chr17_23790223_23790377	0.38	Srrm2	serine/arginine repetitive matrix 2	232	0.78
chr3_127124044_127124345	0.37	Ank2	ankyrin 2, brain	668	0.65
chr3_94954465_94954628	0.36	Rfx5	regulatory factor X, 5 (influences HLA class II expression)	19	0.95
chr1_52454776_52454937	0.36	Gm23460	predicted gene, 23460	10312	0.16
chr12_27357387_27357554	0.35	Sox11	SRY (sex determining region Y)-box 11	14896	0.28
chr12_83488027_83488404	0.34	Dpf3	D4, zinc and double PHD fingers, family 3	499	0.78
chr5_126566218_126566538	0.34	Gm24839	predicted gene, 24839	52397	0.14
chr14_62557877_62558073	0.33	Fam124a	family with sequence similarity 124, member A	2200	0.2
chr11_23855502_23855671	0.33	Papolg	poly(A) polymerase gamma	12884	0.18
chr19_47304311_47304615	0.33	Sh3pxd2a	SH3 and PX domains 2A	10288	0.16
chr12_111722792_111722948	0.30	Gm15995	predicted gene 15995	3522	0.12
chr6_38531788_38531983	0.30	Fmc1	formation of mitochondrial complex V assembly factor 1	1617	0.3
chr13_23506003_23506326	0.28	n-TStga1	nuclear encoded tRNA serine 1 (anticodon TGA)	11978	0.05
chr11_117313106_117313279	0.28	Septin9	septin 9	5038	0.22
chr11_115859676_115859840	0.28	Myo15b	myosin XVB	1352	0.26
chr4_129248394_129248565	0.26	C77080	expressed sequence C77080	36	0.96
chr1_72231055_72231231	0.26	Gm25360	predicted gene, 25360	4903	0.13
chr4_116008423_116008814	0.26	Faah	fatty acid amide hydrolase	8550	0.14
chr17_87974584_87974753	0.25	Msh6	mutS homolog 6	394	0.82
chr7_75861767_75861930	0.25	Klhl25	kelch-like 25	13407	0.22
chr5_115475861_115476388	0.24	Sirt4	sirtuin 4	3814	0.1
chr4_141708335_141708559	0.24	Ddi2	DNA-damage inducible protein 2	14972	0.12
chr17_56467485_56467636	0.24	Ptprs	protein tyrosine phosphatase, receptor type, S	5344	0.16
chr19_59588162_59588313	0.24	Gm18161	predicted gene, 18161	47786	0.13
chr9_50856575_50856749	0.24	Ppp2r1b	protein phosphatase 2, regulatory subunit A, beta	262	0.9
chr4_117605417_117605587	0.24	Eri3	exoribonuclease 3	16424	0.15
chr3_53017166_53017327	0.24	Cog6	component of oligomeric golgi complex 6	9	0.97
chr15_75830872_75831075	0.22	Zc3h3	zinc finger CCCH type containing 3	2764	0.16
chr12_21183631_21184095	0.22	AC156032.1		63460	0.08
chr1_168380081_168380258	0.22	Gm38381	predicted gene, 38381	29361	0.18
chr4_15145228_15145428	0.22	Necab1	N-terminal EF-hand calcium binding protein 1	3633	0.27
chr2_30207072_30207249	0.21	Kyat1	kynurenine aminotransferase 1	1313	0.26
chr4_135872055_135872460	0.21	Pnrc2	proline-rich nuclear receptor coactivator 2	804	0.46
chr1_182336926_182337087	0.21	Fbxo28	F-box protein 28	4565	0.19
chrX_129749825_129749976	0.21	Diaph2	diaphanous related formin 2	76	0.99
chr19_12652059_12652547	0.21	Glyat	glycine-N-acyltransferase	12811	0.09
chr10_43440139_43440316	0.21	Gm3699	predicted gene 3699	16274	0.13
chr15_88864782_88864944	0.20	Pim3	proviral integration site 3	57	0.96
chr3_135498924_135499245	0.20	Gm16100	predicted gene 16100	3431	0.15
chr10_127165534_127165685	0.20	B4galnt1	beta-1,4-N-acetyl-galactosaminyl transferase 1	222	0.84
chr18_64341527_64341710	0.19	Onecut2	one cut domain, family member 2	1598	0.35
chr13_9763714_9763892	0.18	Zmynd11	zinc finger, MYND domain containing 11	547	0.72
chr8_121575170_121575337	0.18	Fbxo31	F-box protein 31	3494	0.14
chr11_96861486_96861931	0.18	Copz2	coatomer protein complex, subunit zeta 2	7577	0.09
chr19_30095671_30095822	0.17	Uhrf2	ubiquitin-like, containing PHD and RING finger domains 2	3785	0.25
chr6_62934342_62934493	0.17	Gm5001	predicted gene 5001	5271	0.31
chr6_108511900_108512071	0.17	Itpr1	inositol 1,4,5-trisphosphate receptor 1	3672	0.19
chr19_33098550_33098701	0.17	Gm29946	predicted gene, 29946	24022	0.18
chr12_116202716_116202878	0.17	Wdr60	WD repeat domain 60	11073	0.12
chr15_36903404_36903565	0.17	Gm10384	predicted gene 10384	23668	0.13
chr8_120409781_120409965	0.16	Gm22715	predicted gene, 22715	33676	0.16
chr17_45592639_45593134	0.16	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	46	0.94
chr7_126346739_126346890	0.16	Gm30928	predicted gene, 30928	4783	0.11
chr17_24007509_24007674	0.16	Gm27700	predicted gene, 27700	2441	0.11
chr11_72411311_72411561	0.16	Smtnl2	smoothelin-like 2	275	0.86
chr14_68297827_68297985	0.16	Gm47212	predicted gene, 47212	79653	0.09
chr11_60074031_60074200	0.16	Pemt	phosphatidylethanolamine N-methyltransferase	27626	0.12
chr19_39648534_39649207	0.16	Cyp2c67	cytochrome P450, family 2, subfamily c, polypeptide 67	181	0.97
chr18_21216011_21216167	0.15	Garem1	GRB2 associated regulator of MAPK1 subtype 1	84034	0.08
chr2_137115323_137115523	0.15	Jag1	jagged 1	1221	0.6
chr4_130520077_130520248	0.15	Nkain1	Na+/K+ transporting ATPase interacting 1	37826	0.17
chr1_187767393_187767632	0.15	AC121143.1	NADH dehydrogenase 2, mitochondrial (mt-Nd2) pseudogene	54707	0.15
chr7_14308064_14308258	0.14	Phf20-ps	PHD finger protein 20, pseudogene	3381	0.19
chr5_145874134_145874475	0.14	Cyp3a11	cytochrome P450, family 3, subfamily a, polypeptide 11	2387	0.26
chr15_82148269_82148913	0.14	Srebf2	sterol regulatory element binding factor 2	566	0.6
chr8_120364518_120364684	0.14	Gm22715	predicted gene, 22715	78948	0.08
chr18_11860532_11860692	0.14	Cables1	CDK5 and Abl enzyme substrate 1	16312	0.16
chr12_83594536_83594711	0.14	Zfyve1	zinc finger, FYVE domain containing 1	1064	0.45
chr2_33452045_33452383	0.14	Gm13536	predicted gene 13536	5412	0.16
chr3_100163971_100164144	0.14	Gdap2	ganglioside-induced differentiation-associated-protein 2	1513	0.33
chr9_86707214_86707391	0.13	Gm22138	predicted gene, 22138	3483	0.13
chr1_59404225_59404406	0.13	Gm29016	predicted gene 29016	25385	0.15
chr7_114292013_114292196	0.13	Psma1	proteasome subunit alpha 1	15986	0.21
chr17_24881412_24881880	0.13	Igfals	insulin-like growth factor binding protein, acid labile subunit	2889	0.1
chr5_115569868_115570025	0.13	Gcn1	GCN1 activator of EIF2AK4	4643	0.11
chr15_78407261_78408064	0.13	Mpst	mercaptopyruvate sulfurtransferase	861	0.37
chr15_35884273_35884596	0.13	Vps13b	vacuolar protein sorting 13B	12712	0.16
chr2_120100029_120100210	0.13	Sptbn5	spectrin beta, non-erythrocytic 5	14441	0.14
chr8_110716150_110716322	0.13	Mtss2	MTSS I-BAR domain containing 2	5240	0.18
chr19_30233010_30233220	0.13	Mbl2	mannose-binding lectin (protein C) 2	173	0.96
chr8_128466385_128467031	0.13	Nrp1	neuropilin 1	107311	0.06
chr3_122984533_122984731	0.13	Usp53	ubiquitin specific peptidase 53	122	0.94
chr19_32242329_32242494	0.12	Sgms1	sphingomyelin synthase 1	3585	0.29
chr2_90504815_90505126	0.12	4933423P22Rik	RIKEN cDNA 4933423P22 gene	25720	0.16
chr6_129254642_129254819	0.12	2310001H17Rik	RIKEN cDNA 2310001H17 gene	16005	0.11
chr13_21945543_21945746	0.12	Zfp184	zinc finger protein 184 (Kruppel-like)	149	0.74
chr1_168475687_168476155	0.12	Mir6348	microRNA 6348	14722	0.24
chr9_83834067_83834712	0.12	Ttk	Ttk protein kinase	300	0.91
chr13_4033707_4033908	0.12	Gm18857	predicted gene, 18857	1438	0.31
chr5_107869751_107869976	0.12	Evi5	ecotropic viral integration site 5	695	0.46
chr11_49712994_49713225	0.12	Cnot6	CCR4-NOT transcription complex, subunit 6	386	0.8
chr5_134295659_134295849	0.12	Gtf2i	general transcription factor II I	146	0.93
chr11_23665861_23666058	0.12	Pex13	peroxisomal biogenesis factor 13	0	0.52
chr8_71603005_71603180	0.12	Fam129c	family with sequence similarity 129, member C	741	0.42
chr4_48253396_48253620	0.12	Erp44	endoplasmic reticulum protein 44	9034	0.2
chr10_95291254_95291431	0.12	Gm48880	predicted gene, 48880	23511	0.13
chr19_44984727_44984892	0.12	4930414N06Rik	RIKEN cDNA 4930414N06 gene	259	0.84
chr10_84060915_84061106	0.11	Gm37908	predicted gene, 37908	748	0.67
chr1_131957507_131957689	0.11	Gm29103	predicted gene 29103	5356	0.12
chrX_20848376_20848541	0.11	Araf	Araf proto-oncogene, serine/threonine kinase	85	0.94
chr11_82020261_82020449	0.11	Gm31522	predicted gene, 31522	388	0.79
chr19_20540260_20540664	0.11	C730002L08Rik	RIKEN cDNA C730002L08 gene	174	0.96
chr13_52223146_52223355	0.11	Gm48199	predicted gene, 48199	42839	0.19
chr11_80167102_80167278	0.10	Adap2os	ArfGAP with dual PH domains 2, opposite strand	10439	0.13
chr17_46646397_46646558	0.10	Mrpl2	mitochondrial ribosomal protein L2	207	0.69
chr13_45457438_45457599	0.10	Gm47455	predicted gene, 47455	26516	0.17
chr7_35342439_35342778	0.10	Rhpn2	rhophilin, Rho GTPase binding protein 2	8278	0.14
chr10_77609232_77609420	0.10	Sumo3	small ubiquitin-like modifier 3	512	0.6
chr1_105317078_105317239	0.10	Gm29014	predicted gene 29014	3963	0.24
chr13_14630649_14630826	0.10	AW209491	expressed sequence AW209491	460	0.73
chr5_125014623_125014796	0.10	Rflna	refilin A	4596	0.2
chr15_86256321_86256487	0.10	Tbc1d22a	TBC1 domain family, member 22a	20899	0.19
chr4_8693785_8693936	0.10	Chd7	chromodomain helicase DNA binding protein 7	2495	0.35
chr11_115832209_115832576	0.10	Llgl2	LLGL2 scribble cell polarity complex component	424	0.7
chr19_36534453_36534632	0.10	Hectd2	HECT domain E3 ubiquitin protein ligase 2	20097	0.2
chr2_118862147_118862313	0.10	Ivd	isovaleryl coenzyme A dehydrogenase	202	0.91
chr2_120464891_120465048	0.09	Capn3	calpain 3	1007	0.46
chr7_72247872_72248068	0.09	Mctp2	multiple C2 domains, transmembrane 2	18610	0.26
chr5_15549725_15549878	0.09	Gm21190	predicted gene, 21190	20579	0.13
chr5_142768854_142769324	0.09	Tnrc18	trinucleotide repeat containing 18	3067	0.26
chr7_131257681_131257832	0.09	Cdcp3	CUB domain containing protein 3	47503	0.09
chr11_85183469_85183675	0.09	1700125H20Rik	RIKEN cDNA 1700125H20 gene	12476	0.13
chr2_25126889_25127229	0.09	AL732309.1	exonuclease 3'-5' domain containing 3 (EXD3) pseudogene	10778	0.08
chr16_92428960_92429111	0.09	Gm46555	predicted gene, 46555	28442	0.11
chr16_93729531_93729931	0.09	Dop1b	DOP1 leucine zipper like protein B	368	0.85
chr7_110096322_110096530	0.09	Zfp143	zinc finger protein 143	4797	0.14
chr10_4334368_4334532	0.09	Akap12	A kinase (PRKA) anchor protein (gravin) 12	95	0.97
chr19_6291962_6292220	0.09	Ehd1	EH-domain containing 1	2090	0.13
chr7_39818171_39818337	0.09	4930558N11Rik	RIKEN cDNA 4930558N11 gene	20512	0.15
chr17_47926111_47926270	0.09	Foxp4	forkhead box P4	1545	0.29
chr14_73325714_73325873	0.09	Rb1	RB transcriptional corepressor 1	29	0.98
chr7_99230091_99230271	0.09	Mogat2	monoacylglycerol O-acyltransferase 2	8413	0.12
chr7_128461344_128461499	0.09	Tial1	Tia1 cytotoxic granule-associated RNA binding protein-like 1	66	0.9
chr15_55547224_55547377	0.08	Mrpl13	mitochondrial ribosomal protein L13	864	0.61
chr17_83935315_83935481	0.08	Gm23905	predicted gene, 23905	12190	0.11
chr8_111053951_111054114	0.08	Exosc6	exosome component 6	2307	0.15
chr14_16598201_16598430	0.08	Rarb	retinoic acid receptor, beta	22488	0.21
chr12_71768786_71769132	0.08	Gm47556	predicted gene, 47556	959	0.59
chr10_8133541_8133713	0.08	Gm30906	predicted gene, 30906	42504	0.18
chr7_102313337_102313504	0.08	Stim1	stromal interaction molecule 1	45093	0.09
chr9_48605290_48605498	0.08	Nnmt	nicotinamide N-methyltransferase	241	0.95
chr9_13297643_13297990	0.08	Maml2	mastermind like transcriptional coactivator 2	141	0.95
chr4_155356437_155356594	0.08	Prkcz	protein kinase C, zeta	4825	0.16
chr8_88199324_88199484	0.08	Tent4b	terminal nucleotidyltransferase 4B	190	0.93
chr13_41226373_41226543	0.08	Elovl2	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 2	6053	0.13
chr19_21031007_21031192	0.08	4930554I06Rik	RIKEN cDNA 4930554I06 gene	73403	0.1
chr6_121865645_121865799	0.08	Mug1	murinoglobulin 1	19855	0.18
chr8_84980308_84980512	0.08	Junb	jun B proto-oncogene	1692	0.13
chr18_76241500_76241662	0.08	Smad2	SMAD family member 2	1	0.98
chr11_96788704_96788867	0.08	Cbx1	chromobox 1	342	0.79
chr11_5402470_5402635	0.07	Znrf3	zinc and ring finger 3	20812	0.18
chr5_70735708_70735881	0.07	Gabrg1	gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1	106410	0.07
chr5_53469821_53470044	0.07	Rbpj	recombination signal binding protein for immunoglobulin kappa J region	3780	0.25
chr11_96035249_96035421	0.07	Snf8	SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae)	370	0.72
chr4_119233398_119233632	0.07	P3h1	prolyl 3-hydroxylase 1	285	0.7
chr14_21522234_21522697	0.07	Kat6b	K(lysine) acetyltransferase 6B	5590	0.25
chr8_87093816_87094174	0.07	Gm5118	predicted gene 5118	688	0.66
chr14_34298539_34299045	0.07	Shld2	shieldin complex subunit 2	1537	0.24
chr5_38561684_38561885	0.07	Wdr1	WD repeat domain 1	22	0.97
chr19_30241056_30241233	0.07	Mbl2	mannose-binding lectin (protein C) 2	8202	0.21
chr3_108911697_108911858	0.07	Prpf38b	PRP38 pre-mRNA processing factor 38 (yeast) domain containing B	50	0.96
chr8_45794944_45795095	0.07	Sorbs2	sorbin and SH3 domain containing 2	8189	0.16
chr6_108773223_108773381	0.07	Arl8b	ADP-ribosylation factor-like 8B	9797	0.23
chr9_65607205_65607476	0.07	Pif1	PIF1 5'-to-3' DNA helicase	20114	0.13
chr17_83525682_83525983	0.07	Cox7a2l	cytochrome c oxidase subunit 7A2 like	8502	0.26
chr7_53604334_53604505	0.07	Mir6238	microRNA 6238	287470	0.01
chr2_28840575_28840979	0.07	Ddx31	DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 31	318	0.56
chr13_93442726_93443017	0.06	Gm6109	predicted gene 6109	5617	0.16
chr11_120831406_120831995	0.06	Gm11773	predicted gene 11773	671	0.52
chr1_75010536_75010846	0.06	Nhej1	non-homologous end joining factor 1	35948	0.1
chr13_58756508_58756704	0.06	Rpl13-ps2	ribosomal protein L13, pseudogene 2	55	0.96
chr2_131881708_131882048	0.06	Erv3	endogenous retroviral sequence 3	22131	0.1
chr10_42277646_42277818	0.06	Foxo3	forkhead box O3	977	0.64
chr10_62651277_62651445	0.06	Ddx50	DEAD (Asp-Glu-Ala-Asp) box polypeptide 50	143	0.93
chr16_29944225_29944722	0.06	Gm26569	predicted gene, 26569	2043	0.31
chr16_77501096_77501279	0.06	Mir99ahg	Mir99a and Mirlet7c-1 host gene (non-protein coding)	803	0.51
chr5_130266836_130266987	0.06	Tyw1	tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)	7981	0.13
chr15_10719115_10719326	0.06	4930556M19Rik	RIKEN cDNA 4930556M19 gene	1369	0.44
chr5_136171356_136171939	0.06	Orai2	ORAI calcium release-activated calcium modulator 2	934	0.4
chr1_40169151_40169486	0.06	Il1r1	interleukin 1 receptor, type I	55762	0.1
chr9_48339748_48339930	0.06	Nxpe2	neurexophilin and PC-esterase domain family, member 2	995	0.58
chr4_126262494_126262652	0.06	Trappc3	trafficking protein particle complex 3	173	0.92
chr5_32311758_32312085	0.06	Gm15615	predicted gene 15615	198	0.94
chr8_111538280_111538723	0.06	Znrf1	zinc and ring finger 1	36	0.98

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb49

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View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.3	GO:0006391	transcription initiation from mitochondrial promoter(GO:0006391)
0.1	0.2	GO:0000710	meiotic mismatch repair(GO:0000710)
0.1	0.2	GO:0098904	regulation of AV node cell action potential(GO:0098904)
0.0	0.1	GO:0048294	negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.0	0.2	GO:0030259	lipid glycosylation(GO:0030259)
0.0	0.1	GO:2000325	regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.0	0.1	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.0	0.2	GO:0061179	negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0	0.7	GO:0019373	epoxygenase P450 pathway(GO:0019373)
0.0	0.1	GO:0006551	leucine metabolic process(GO:0006551)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:0072015	glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0	0.1	GO:0007221	positive regulation of transcription of Notch receptor target(GO:0007221)
0.0	0.2	GO:0046322	negative regulation of fatty acid oxidation(GO:0046322)
0.0	0.1	GO:0010739	positive regulation of protein kinase A signaling(GO:0010739)
0.0	0.0	GO:0042360	vitamin E metabolic process(GO:0042360)
0.0	0.1	GO:1901873	regulation of post-translational protein modification(GO:1901873) negative regulation of post-translational protein modification(GO:1901874)
0.0	0.1	GO:0016560	protein import into peroxisome matrix, docking(GO:0016560)
0.0	0.1	GO:0072367	regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367)
0.0	0.0	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.1	GO:0001867	complement activation, lectin pathway(GO:0001867)
0.0	0.1	GO:2000382	positive regulation of mesoderm development(GO:2000382)
0.0	0.0	GO:0014717	regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014717) satellite cell activation involved in skeletal muscle regeneration(GO:0014901)
0.0	0.0	GO:0036215	response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0	0.1	GO:0032463	negative regulation of protein homooligomerization(GO:0032463)
0.0	0.0	GO:0070375	ERK5 cascade(GO:0070375)
0.0	0.1	GO:1901300	positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0	0.0	GO:0009092	homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0	0.0	GO:0000715	nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0	0.2	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.2	GO:2001241	positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0	0.0	GO:0035093	spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0	0.1	GO:0072675	osteoclast fusion(GO:0072675)
0.0	0.0	GO:0001880	Mullerian duct regression(GO:0001880)
0.0	0.0	GO:1900451	positive regulation of glutamate receptor signaling pathway(GO:1900451) positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000969)
0.0	0.1	GO:0061002	negative regulation of dendritic spine morphogenesis(GO:0061002)

Gene overrepresentation in cellular component category:

Total log-likelihood	Term	Description
0.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.2	GO:0032300	mismatch repair complex(GO:0032300)
0.1	GO:0032444	activin responsive factor complex(GO:0032444)
0.2	GO:0017119	Golgi transport complex(GO:0017119)
0.1	GO:0035189	Rb-E2F complex(GO:0035189)
0.3	GO:0071565	nBAF complex(GO:0071565)
0.1	GO:0000814	ESCRT II complex(GO:0000814)
0.2	GO:0031430	M band(GO:0031430)
0.0	GO:0000110	nucleotide-excision repair factor 1 complex(GO:0000110)
0.0	GO:0010009	cytoplasmic side of endosome membrane(GO:0010009)
0.1	GO:0001940	male pronucleus(GO:0001940)
0.0	GO:0031088	platelet dense granule membrane(GO:0031088)
0.0	GO:0002193	MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0032137	guanine/thymine mispair binding(GO:0032137)
0.0	0.4	GO:0008239	dipeptidyl-peptidase activity(GO:0008239)
0.0	0.2	GO:0005534	galactose binding(GO:0005534)
0.0	0.1	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.2	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0008301	DNA binding, bending(GO:0008301)
0.0	0.1	GO:0031802	type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0	0.1	GO:0031849	olfactory receptor binding(GO:0031849)
0.0	0.1	GO:0070548	L-glutamine aminotransferase activity(GO:0070548)
0.0	0.6	GO:0070330	aromatase activity(GO:0070330)
0.0	0.0	GO:0019797	procollagen-proline 3-dioxygenase activity(GO:0019797)
0.0	0.2	GO:0008601	protein phosphatase type 2A regulator activity(GO:0008601)
0.0	0.1	GO:0004792	thiosulfate sulfurtransferase activity(GO:0004792)
0.0	0.1	GO:0005072	transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0	0.1	GO:0031386	protein tag(GO:0031386)
0.0	0.1	GO:1990226	histone methyltransferase binding(GO:1990226)
0.0	0.1	GO:0001161	intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0	0.2	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0004652	polynucleotide adenylyltransferase activity(GO:0004652)
0.0	0.0	GO:0005220	inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators
0.0	0.2	REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1	Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1