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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Zfp282

Z-value: 1.52

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Transcription factors associated with Zfp282

Gene Symbol	Gene ID	Gene Info
Zfp282 Ensembl NCBI MGI UniProt	ENSMUSG00000025821.9	Zfp282

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Zfp282	chr6_47877547_47877732	17	0.964150	-0.79	6.0e-02	Click!
Zfp282	chr6_47877737_47877913	169	0.923592	-0.62	1.9e-01	Click!
Zfp282	chr6_47879323_47879519	1765	0.249621	-0.33	5.2e-01	Click!
Zfp282	chr6_47878038_47878359	542	0.674152	0.29	5.7e-01	Click!
Zfp282	chr6_47878452_47878609	874	0.477761	0.01	9.8e-01	Click!

Activity of the Zfp282 motif across conditions

Conditions sorted by the z-value of the Zfp282 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr17_35866032_35866679	1.04	Ppp1r18	protein phosphatase 1, regulatory subunit 18	260	0.6
chr2_58792449_58792713	0.97	Upp2	uridine phosphorylase 2	27256	0.17
chr12_87443355_87443540	0.92	Alkbh1	alkB homolog 1, histone H2A dioxygenase	379	0.44
chr10_95144611_95144805	0.78	Gm29684	predicted gene, 29684	1117	0.44
chr12_16563277_16563428	0.77	Lpin1	lipin 1	908	0.68
chr11_120813788_120814608	0.76	Fasn	fatty acid synthase	1257	0.26
chr14_120498503_120498675	0.70	Rap2a	RAS related protein 2a	20145	0.24
chr8_93168995_93169226	0.69	Ces1d	carboxylesterase 1D	865	0.51
chr16_24877530_24877720	0.67	Gm22672	predicted gene, 22672	6548	0.24
chr14_68809096_68809247	0.67	Gm47256	predicted gene, 47256	65664	0.11
chrX_85827473_85827635	0.64	Gm14762	predicted gene 14762	893	0.5
chr11_69098275_69098686	0.62	Per1	period circadian clock 1	468	0.58
chr14_11358016_11358174	0.61	Gm3839	predicted pseudogene 3839	1369	0.42
chr1_75045469_75045620	0.60	Nhej1	non-homologous end joining factor 1	1095	0.44
chr1_133348155_133348321	0.59	Ren1	renin 1 structural	2272	0.2
chr11_105905841_105906025	0.58	Tanc2	tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2	3950	0.17
chr13_4270977_4271134	0.58	Akr1c12	aldo-keto reductase family 1, member C12	8378	0.15
chr12_16864896_16865104	0.57	Gm36495	predicted gene, 36495	14119	0.14
chr4_53262351_53262525	0.56	AI427809	expressed sequence AI427809	109	0.96
chr5_91259410_91259561	0.56	Gm19619	predicted gene, 19619	23936	0.19
chr4_53475197_53475646	0.54	Slc44a1	solute carrier family 44, member 1	34737	0.17
chr3_93469367_93469518	0.53	Tchhl1	trichohyalin-like 1	688	0.49
chr8_110000217_110000533	0.53	Tat	tyrosine aminotransferase	9869	0.12
chr4_137891903_137892213	0.52	Gm13012	predicted gene 13012	8121	0.21
chr11_90371132_90371283	0.51	Hlf	hepatic leukemia factor	10728	0.26
chr10_96649866_96650017	0.50	Btg1	BTG anti-proliferation factor 1	32387	0.16
chr7_30514994_30515293	0.50	Arhgap33os	Rho GTPase activating protein 33, opposite strand	21	0.92
chr10_81414192_81414360	0.49	Mir1191b	microRNA 1191b	2021	0.11
chr2_156392250_156392474	0.49	2900097C17Rik	RIKEN cDNA 2900097C17 gene	467	0.64
chr2_135035898_135036246	0.48	4930545L23Rik	RIKEN cDNA 4930545L23 gene	179544	0.03
chr2_64095519_64096038	0.48	Fign	fidgetin	2210	0.48
chr2_160364625_160364776	0.48	Mafb	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein B (avian)	2365	0.37
chr4_14810853_14811073	0.48	Lrrc69	leucine rich repeat containing 69	14903	0.18
chr6_120008206_120008357	0.48	Gm16199	predicted gene 16199	2283	0.27
chr2_109919434_109919722	0.48	Lgr4	leucine-rich repeat-containing G protein-coupled receptor 4	1931	0.32
chr5_112287930_112288081	0.47	Tpst2	protein-tyrosine sulfotransferase 2	757	0.52
chr2_92381925_92382198	0.47	1700029I15Rik	RIKEN cDNA 1700029I15 gene	477	0.66
chr3_97637473_97637939	0.47	Fmo5	flavin containing monooxygenase 5	8823	0.13
chr3_84813766_84813917	0.47	Fbxw7	F-box and WD-40 domain protein 7	1427	0.53
chr8_88203572_88203796	0.46	Tent4b	terminal nucleotidyltransferase 4B	4470	0.18
chr8_11021555_11021713	0.46	Irs2	insulin receptor substrate 2	13176	0.13
chr14_21295488_21295639	0.46	Adk	adenosine kinase	22562	0.24
chr6_138141951_138142295	0.45	Mgst1	microsomal glutathione S-transferase 1	537	0.85
chr16_28895542_28895693	0.45	Mb21d2	Mab-21 domain containing 2	34056	0.2
chr7_72209931_72210100	0.45	Mctp2	multiple C2 domains, transmembrane 2	19345	0.23
chr15_99032785_99032993	0.45	Tuba1c	tubulin, alpha 1C	2568	0.14
chr13_52736115_52736276	0.43	BB123696	expressed sequence BB123696	587	0.84
chr16_14152143_14152374	0.43	Marf1	meiosis regulator and mRNA stability 1	7009	0.14
chr5_28061144_28061343	0.43	Gm26608	predicted gene, 26608	5784	0.17
chr7_127800722_127801079	0.43	Hsd3b7	hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7	16	0.92
chr11_16837434_16837735	0.43	Egfros	epidermal growth factor receptor, opposite strand	6882	0.22
chr15_83202825_83203000	0.42	7530414M10Rik	RIKEN cDNA 7530414M10 gene	26467	0.1
chr9_102981639_102981813	0.42	Slco2a1	solute carrier organic anion transporter family, member 2a1	6986	0.18
chr18_36725667_36726187	0.42	Cd14	CD14 antigen	811	0.38
chr14_63326787_63326957	0.41	Gm5463	predicted gene 5463	2348	0.25
chr2_27735063_27735214	0.41	Rxra	retinoid X receptor alpha	5063	0.29
chr2_18031546_18031742	0.41	Gm13330	predicted gene 13330	889	0.42
chr12_81860812_81860999	0.41	Pcnx	pecanex homolog	564	0.78
chr9_23224794_23225147	0.40	Bmper	BMP-binding endothelial regulator	1684	0.55
chr5_51874876_51875093	0.40	Gm42616	predicted gene 42616	4618	0.19
chr14_88463159_88463310	0.40	Pcdh20	protocadherin 20	8112	0.23
chr7_99062840_99062991	0.40	Gm33882	predicted gene, 33882	27317	0.14
chr11_60782221_60782394	0.40	Smcr8	Smith-Magenis syndrome chromosome region, candidate 8 homolog (human)	4782	0.09
chr6_114866683_114866890	0.39	Vgll4	vestigial like family member 4	2029	0.33
chr3_138261022_138261219	0.39	Adh1	alcohol dehydrogenase 1 (class I)	129	0.94
chr1_150993778_150993941	0.39	Hmcn1	hemicentin 1	424	0.83
chr3_51226339_51227024	0.39	Noct	nocturnin	2211	0.23
chr5_34409004_34409235	0.39	Fam193a	family with sequence homology 193, member A	17218	0.13
chr18_84862488_84862777	0.39	Gm16146	predicted gene 16146	3046	0.21
chr6_119419039_119419208	0.38	Adipor2	adiponectin receptor 2	1419	0.44
chr8_122979971_122980234	0.38	Gm24445	predicted gene, 24445	2841	0.19
chr9_20869353_20869677	0.38	Shfl	shiftless antiviral inhibitor of ribosomal frameshifting	238	0.82
chr13_9493955_9494714	0.38	Gm48871	predicted gene, 48871	48434	0.12
chr15_74708640_74708963	0.38	4933427E11Rik	RIKEN cDNA 4933427E11 gene	360	0.59
chr6_129095497_129095663	0.38	Clec2e	C-type lectin domain family 2, member e	5333	0.12
chr6_54048644_54048819	0.38	Chn2	chimerin 2	8645	0.22
chr3_88144051_88144795	0.37	Mef2d	myocyte enhancer factor 2D	1849	0.2
chr11_43170710_43170884	0.37	Atp10b	ATPase, class V, type 10B	15126	0.2
chr10_87896571_87896873	0.37	Igf1os	insulin-like growth factor 1, opposite strand	33341	0.15
chr4_63084799_63084953	0.37	Zfp618	zinc finger protein 618	35524	0.16
chr4_62703120_62703271	0.37	Rgs3	regulator of G-protein signaling 3	2500	0.23
chr6_6149940_6150263	0.36	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	23850	0.23
chr14_60980883_60981065	0.36	Tnfrsf19	tumor necrosis factor receptor superfamily, member 19	5089	0.27
chr9_21227746_21227897	0.36	Gm16754	predicted gene, 16754	2418	0.14
chr5_124424178_124424509	0.36	Gm37415	predicted gene, 37415	354	0.67
chr10_67189121_67189327	0.36	Jmjd1c	jumonji domain containing 1C	3471	0.26
chr9_46067501_46067769	0.36	Sik3	SIK family kinase 3	54635	0.09
chr10_118455975_118456145	0.35	Gm49751	predicted gene, 49751	14641	0.16
chr16_11066434_11066585	0.35	Snn	stannin	179	0.68
chr5_32458502_32458674	0.35	Ppp1cb	protein phosphatase 1 catalytic subunit beta	255	0.83
chr4_133162666_133162838	0.35	Wasf2	WAS protein family, member 2	13249	0.14
chr11_101416742_101416924	0.35	Aarsd1	alanyl-tRNA synthetase domain containing 1	549	0.46
chr10_20148225_20148689	0.34	Map7	microtubule-associated protein 7	14	0.98
chr2_53190893_53191069	0.34	Prpf40a	pre-mRNA processing factor 40A	191	0.87
chr2_34774806_34775255	0.34	Hspa5	heat shock protein 5	183	0.92
chr2_155070325_155070499	0.34	Gm45609	predicted gene 45609	3769	0.16
chr8_46512530_46512928	0.34	Acsl1	acyl-CoA synthetase long-chain family member 1	14057	0.15
chr14_35144080_35144240	0.34	Gm49034	predicted gene, 49034	75278	0.12
chr16_46100408_46100565	0.34	Gm50487	predicted gene, 50487	14011	0.18
chr14_21090695_21090906	0.34	Adk	adenosine kinase	14648	0.21
chr15_103273039_103273393	0.33	Copz1	coatomer protein complex, subunit zeta 1	304	0.8
chr4_86897207_86897408	0.33	Acer2	alkaline ceramidase 2	22893	0.19
chr10_80684012_80684199	0.33	Mknk2	MAP kinase-interacting serine/threonine kinase 2	5993	0.09
chr9_57262499_57262900	0.33	1700017B05Rik	RIKEN cDNA 1700017B05 gene	87	0.96
chr14_52196558_52196748	0.33	Supt16	SPT16, facilitates chromatin remodeling subunit	763	0.35
chr8_20262284_20262575	0.33	6820431F20Rik	RIKEN cDNA 6820431F20 gene	20837	0.21
chr10_20153471_20153802	0.33	Map7	microtubule-associated protein 7	4638	0.2
chr17_32272780_32272931	0.33	Brd4	bromodomain containing 4	490	0.72
chr5_66034454_66034632	0.33	Rbm47	RNA binding motif protein 47	20009	0.11
chr4_45403274_45403659	0.32	Slc25a51	solute carrier family 25, member 51	1400	0.35
chr7_115674458_115674622	0.32	Sox6	SRY (sex determining region Y)-box 6	12175	0.3
chr7_90426036_90426299	0.32	Ccdc89	coiled-coil domain containing 89	410	0.78
chr6_115717866_115718504	0.32	Gm24008	predicted gene, 24008	5647	0.12
chr4_135789148_135789435	0.32	Myom3	myomesin family, member 3	8899	0.14
chr1_70928023_70928290	0.31	Gm16236	predicted gene 16236	111874	0.07
chr18_69346822_69346973	0.31	Tcf4	transcription factor 4	402	0.9
chr2_58775472_58775623	0.31	Upp2	uridine phosphorylase 2	10222	0.21
chr13_95828839_95829073	0.31	Iqgap2	IQ motif containing GTPase activating protein 2	62801	0.1
chr3_14853846_14854027	0.31	Car3	carbonic anhydrase 3	9576	0.18
chr4_14865092_14865411	0.31	Pip4p2	phosphatidylinositol-4,5-bisphosphate 4-phosphatase 2	1175	0.52
chr19_4587227_4587438	0.31	Pcx	pyruvate carboxylase	7014	0.13
chr2_69862179_69862453	0.31	Ssb	Sjogren syndrome antigen B	630	0.59
chr10_19552959_19553256	0.31	Gm48563	predicted gene, 48563	30457	0.15
chr10_75782918_75783155	0.31	Gstt3	glutathione S-transferase, theta 3	1622	0.19
chr7_114778861_114779234	0.30	Insc	INSC spindle orientation adaptor protein	7726	0.19
chr3_52267357_52267508	0.30	Foxo1	forkhead box O1	904	0.44
chr17_80676724_80676977	0.30	Map4k3	mitogen-activated protein kinase kinase kinase kinase 3	25700	0.2
chr4_122955991_122956232	0.30	Mfsd2a	major facilitator superfamily domain containing 2A	3879	0.16
chr13_59536214_59536381	0.30	Agtpbp1	ATP/GTP binding protein 1	2225	0.26
chr4_155234884_155235204	0.30	Ski	ski sarcoma viral oncogene homolog (avian)	12452	0.15
chr18_51125971_51126159	0.30	Prr16	proline rich 16	8327	0.31
chr6_116895920_116896071	0.29	Gm43926	predicted gene, 43926	57524	0.12
chr8_56564027_56564192	0.29	Gm25992	predicted gene, 25992	2808	0.19
chr6_29694571_29694929	0.29	Tspan33	tetraspanin 33	516	0.77
chr5_124421900_124422062	0.29	Sbno1	strawberry notch 1	2094	0.17
chr6_70843849_70844027	0.29	Eif2ak3	eukaryotic translation initiation factor 2 alpha kinase 3	577	0.7
chr12_104342354_104343298	0.29	Serpina3k	serine (or cysteine) peptidase inhibitor, clade A, member 3K	4340	0.13
chr6_87277564_87277945	0.29	Gm44418	predicted gene, 44418	9	0.96
chr17_24632818_24632990	0.29	Nthl1	nth (endonuclease III)-like 1 (E.coli)	185	0.57
chr13_43530666_43530856	0.28	Gm32939	predicted gene, 32939	541	0.71
chr2_134554640_134554803	0.28	Hao1	hydroxyacid oxidase 1, liver	353	0.93
chr8_114148783_114148961	0.28	Nudt7	nudix (nucleoside diphosphate linked moiety X)-type motif 7	15230	0.26
chr17_46680513_46680702	0.28	Mea1	male enhanced antigen 1	88	0.62
chr13_37434601_37434752	0.28	Gm4035	predicted gene 4035	473	0.7
chr15_39816605_39817118	0.28	Gm16291	predicted gene 16291	19816	0.18
chr5_99284196_99284371	0.28	Gm35394	predicted gene, 35394	10188	0.24
chr1_58734421_58734701	0.28	Cflar	CASP8 and FADD-like apoptosis regulator	4009	0.16
chr11_32224531_32225077	0.28	Mpg	N-methylpurine-DNA glycosylase	1701	0.21
chr4_53133117_53133354	0.28	Abca1	ATP-binding cassette, sub-family A (ABC1), member 1	26660	0.18
chr13_9765507_9765695	0.27	Zmynd11	zinc finger, MYND domain containing 11	271	0.89
chr10_54058863_54059129	0.27	Gm47917	predicted gene, 47917	4815	0.22
chr1_92667223_92667402	0.27	Otos	otospiralin	18471	0.1
chr17_32492940_32493118	0.27	Cyp4f39	cytochrome P450, family 4, subfamily f, polypeptide 39	871	0.5
chr4_120816433_120816604	0.27	Nfyc	nuclear transcription factor-Y gamma	806	0.51
chr12_3890925_3891725	0.27	Dnmt3a	DNA methyltransferase 3A	403	0.83
chr2_84996201_84996436	0.27	Prg3	proteoglycan 3	8103	0.12
chr3_130214224_130214407	0.27	Gm22682	predicted gene, 22682	8850	0.21
chrX_23710209_23710816	0.27	Wdr44	WD repeat domain 44	17353	0.28
chr9_78513509_78513701	0.27	Gm47430	predicted gene, 47430	6941	0.13
chr7_27329424_27329588	0.27	Ltbp4	latent transforming growth factor beta binding protein 4	4107	0.13
chr19_29978982_29979139	0.27	Gm26046	predicted gene, 26046	7039	0.18
chr7_34230685_34230836	0.27	Gpi1	glucose-6-phosphate isomerase 1	424	0.67
chr2_165791815_165791993	0.27	Eya2	EYA transcriptional coactivator and phosphatase 2	22718	0.17
chr1_31094512_31094669	0.26	4931428L18Rik	RIKEN cDNA 4931428L18 gene	1864	0.29
chr16_4321605_4321756	0.26	Gm6142	predicted pseudogene 6142	1000	0.59
chr1_88044569_88044899	0.26	AC087801.1	UDP glycosyltransferase 1 family (Ytg1) pseudogene	7134	0.08
chr2_90494801_90494975	0.26	4933423P22Rik	RIKEN cDNA 4933423P22 gene	15638	0.17
chr19_29668488_29668647	0.26	Ermp1	endoplasmic reticulum metallopeptidase 1	20152	0.17
chr5_123001764_123001915	0.26	Gm44574	predicted gene 44574	11035	0.09
chr3_67430526_67430935	0.26	Gfm1	G elongation factor, mitochondrial 1	614	0.7
chr2_64971609_64972024	0.26	Grb14	growth factor receptor bound protein 14	3930	0.34
chr2_63861256_63861458	0.26	Fign	fidgetin	236631	0.02
chrX_76137735_76137886	0.26	Gm14710	predicted gene 14710	24795	0.17
chr5_123076789_123076960	0.26	Tmem120b	transmembrane protein 120B	504	0.62
chr15_59657545_59657701	0.25	Trib1	tribbles pseudokinase 1	8970	0.2
chr13_82201076_82201227	0.25	Gm48155	predicted gene, 48155	111394	0.07
chr2_134549597_134549818	0.25	Hao1	hydroxyacid oxidase 1, liver	4600	0.33
chr4_9825489_9825685	0.25	Gdf6	growth differentiation factor 6	18785	0.21
chr5_145190659_145190910	0.25	Atp5j2	ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2	727	0.48
chr6_141944415_141944591	0.25	Slco1a1	solute carrier organic anion transporter family, member 1a1	2307	0.35
chr10_24951900_24952743	0.25	Gm36172	predicted gene, 36172	24702	0.12
chr7_130989257_130989408	0.25	Htra1	HtrA serine peptidase 1	6602	0.21
chr2_32612430_32612590	0.25	St6galnac6	ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6	3467	0.1
chr9_69623415_69623593	0.25	Gm47203	predicted gene, 47203	23750	0.21
chr4_74251698_74252250	0.25	Kdm4c	lysine (K)-specific demethylase 4C	38	0.78
chr14_105176440_105176633	0.25	Rbm26	RNA binding motif protein 26	324	0.87
chr5_135957340_135957526	0.25	Ssc4d	scavenger receptor cysteine rich family, 4 domains	4838	0.13
chr15_53166677_53166864	0.25	Ext1	exostosin glycosyltransferase 1	29485	0.26
chr10_8928866_8929030	0.25	Gm48728	predicted gene, 48728	23001	0.15
chr18_12655181_12655597	0.25	Gm41668	predicted gene, 41668	6970	0.15
chr18_12729849_12730702	0.25	Ttc39c	tetratricopeptide repeat domain 39C	4430	0.15
chr15_75314247_75314423	0.25	Gm3454	predicted gene 3454	629	0.56
chr13_53377028_53377241	0.24	Sptlc1	serine palmitoyltransferase, long chain base subunit 1	214	0.94
chr16_24448114_24448329	0.24	Lpp	LIM domain containing preferred translocation partner in lipoma	130	0.97
chr6_29772335_29772499	0.24	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	3889	0.2
chr12_72536046_72536412	0.24	Pcnx4	pecanex homolog 4	154	0.96
chr12_41851974_41852350	0.24	Gm47371	predicted gene, 47371	23639	0.25
chr12_54162747_54163149	0.24	Egln3	egl-9 family hypoxia-inducible factor 3	40912	0.13
chr9_47529383_47529534	0.24	Cadm1	cell adhesion molecule 1	715	0.67
chr17_12941947_12942098	0.24	Acat3	acetyl-Coenzyme A acetyltransferase 3	1422	0.21

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp282

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0006982	response to lipid hydroperoxide(GO:0006982)
0.1	0.4	GO:0097167	circadian regulation of translation(GO:0097167)
0.1	0.4	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.1	0.7	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.1	0.2	GO:0045472	response to ether(GO:0045472)
0.1	0.3	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.1	0.6	GO:0042118	endothelial cell activation(GO:0042118)
0.1	0.2	GO:0006667	sphinganine metabolic process(GO:0006667)
0.1	0.3	GO:0070814	hydrogen sulfide biosynthetic process(GO:0070814)
0.1	0.4	GO:0006642	triglyceride mobilization(GO:0006642)
0.1	0.4	GO:0006307	DNA dealkylation involved in DNA repair(GO:0006307)
0.1	0.3	GO:0046499	S-adenosylmethioninamine metabolic process(GO:0046499)
0.1	0.2	GO:0003330	regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.1	0.2	GO:0060468	prevention of polyspermy(GO:0060468)
0.1	0.2	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.1	0.2	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.1	0.2	GO:0035284	central nervous system segmentation(GO:0035283) brain segmentation(GO:0035284)
0.1	0.1	GO:0008065	establishment of blood-nerve barrier(GO:0008065)
0.1	0.2	GO:0071727	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1	0.2	GO:0006987	activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1	0.2	GO:0019859	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1	0.2	GO:0006285	base-excision repair, AP site formation(GO:0006285)
0.1	0.2	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.1	0.2	GO:0006562	proline catabolic process(GO:0006562)
0.1	0.2	GO:0070125	mitochondrial translational elongation(GO:0070125)
0.0	0.1	GO:0010911	regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912)
0.0	0.2	GO:0032055	negative regulation of translation in response to stress(GO:0032055)
0.0	0.4	GO:0006707	cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0	0.1	GO:0002254	kinin cascade(GO:0002254)
0.0	0.2	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.1	GO:1900222	negative regulation of beta-amyloid clearance(GO:1900222)
0.0	0.2	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:1900095	regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0	0.1	GO:0035964	COPI-coated vesicle budding(GO:0035964)
0.0	0.2	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.3	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.1	GO:0000379	tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0	0.2	GO:0006572	tyrosine catabolic process(GO:0006572)
0.0	0.1	GO:1904479	negative regulation of intestinal absorption(GO:1904479)
0.0	0.1	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.1	GO:0048162	preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0	0.1	GO:1901097	negative regulation of autophagosome maturation(GO:1901097)
0.0	0.2	GO:0051987	positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0	0.2	GO:0042271	susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0	0.4	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.1	GO:0090202	transcriptional activation by promoter-enhancer looping(GO:0071733) gene looping(GO:0090202) dsDNA loop formation(GO:0090579)
0.0	0.2	GO:0006102	isocitrate metabolic process(GO:0006102)
0.0	0.1	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.2	GO:0060687	regulation of branching involved in prostate gland morphogenesis(GO:0060687)
0.0	0.1	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0	0.2	GO:0009438	methylglyoxal metabolic process(GO:0009438)
0.0	0.1	GO:0032489	regulation of Cdc42 protein signal transduction(GO:0032489)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:0090296	regulation of mitochondrial DNA replication(GO:0090296)
0.0	0.1	GO:0016554	cytidine to uridine editing(GO:0016554)
0.0	0.1	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.1	GO:2000169	regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0	0.1	GO:0048625	myoblast fate commitment(GO:0048625)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.2	GO:0043983	histone H4-K12 acetylation(GO:0043983)
0.0	0.1	GO:0001561	fatty acid alpha-oxidation(GO:0001561)
0.0	0.2	GO:0070072	vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0	0.1	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.2	GO:0097062	dendritic spine maintenance(GO:0097062)
0.0	0.1	GO:0048320	axial mesoderm formation(GO:0048320)
0.0	0.1	GO:0090194	negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.0	0.1	GO:0016255	attachment of GPI anchor to protein(GO:0016255)
0.0	0.1	GO:0006646	phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0	0.1	GO:0072366	regulation of cellular ketone metabolic process by positive regulation of transcription from RNA polymerase II promoter(GO:0072366)
0.0	0.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.0	0.3	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0	0.2	GO:0006488	dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0	0.1	GO:2000870	regulation of progesterone secretion(GO:2000870)
0.0	0.1	GO:0043321	regulation of natural killer cell degranulation(GO:0043321)
0.0	0.1	GO:0015014	heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0	0.1	GO:0048861	leukemia inhibitory factor signaling pathway(GO:0048861)
0.0	0.2	GO:2000010	positive regulation of protein localization to cell surface(GO:2000010)
0.0	0.1	GO:0061086	negative regulation of histone H3-K27 methylation(GO:0061086)
0.0	0.0	GO:0072131	kidney mesenchyme morphogenesis(GO:0072131) metanephric mesenchyme morphogenesis(GO:0072133)
0.0	0.1	GO:2000271	positive regulation of fibroblast apoptotic process(GO:2000271)
0.0	0.1	GO:0048069	eye pigmentation(GO:0048069)
0.0	0.1	GO:0071276	cellular response to cadmium ion(GO:0071276)
0.0	0.1	GO:0015747	urate transport(GO:0015747)
0.0	0.1	GO:1903288	regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.0	0.1	GO:0090283	regulation of protein glycosylation in Golgi(GO:0090283)
0.0	0.2	GO:0075522	IRES-dependent viral translational initiation(GO:0075522)
0.0	0.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0002036	regulation of L-glutamate transport(GO:0002036)
0.0	0.2	GO:0048752	semicircular canal morphogenesis(GO:0048752)
0.0	0.1	GO:0071033	nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.2	GO:0032367	intracellular cholesterol transport(GO:0032367)
0.0	0.1	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0035912	dorsal aorta development(GO:0035907) dorsal aorta morphogenesis(GO:0035912)
0.0	0.1	GO:2000741	positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0	0.1	GO:0035609	C-terminal protein deglutamylation(GO:0035609)
0.0	0.0	GO:2000618	regulation of histone H4-K16 acetylation(GO:2000618)
0.0	0.1	GO:0039689	negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034)
0.0	0.1	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0	0.1	GO:0070544	histone H3-K36 demethylation(GO:0070544)
0.0	0.1	GO:0042590	antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0	0.1	GO:0006526	arginine biosynthetic process(GO:0006526)
0.0	0.0	GO:0035610	protein side chain deglutamylation(GO:0035610)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.1	GO:0061073	ciliary body morphogenesis(GO:0061073)
0.0	0.0	GO:0033686	positive regulation of luteinizing hormone secretion(GO:0033686)
0.0	0.1	GO:1903798	regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798)
0.0	0.1	GO:0022605	oogenesis stage(GO:0022605)
0.0	0.1	GO:2000857	positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0	0.1	GO:0051382	kinetochore assembly(GO:0051382)
0.0	0.1	GO:1903689	regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0	0.1	GO:0002370	natural killer cell cytokine production(GO:0002370) regulation of natural killer cell cytokine production(GO:0002727)
0.0	0.2	GO:0019985	translesion synthesis(GO:0019985)
0.0	0.1	GO:0006537	glutamate biosynthetic process(GO:0006537)
0.0	0.1	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0	0.1	GO:0061113	pancreas morphogenesis(GO:0061113)
0.0	0.0	GO:0031860	telomeric 3' overhang formation(GO:0031860)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.2	GO:0006895	Golgi to endosome transport(GO:0006895)
0.0	0.0	GO:0006559	L-phenylalanine catabolic process(GO:0006559) erythrose 4-phosphate/phosphoenolpyruvate family amino acid catabolic process(GO:1902222)
0.0	0.0	GO:0038095	Fc-epsilon receptor signaling pathway(GO:0038095)
0.0	0.0	GO:1902965	regulation of protein localization to early endosome(GO:1902965) positive regulation of protein localization to early endosome(GO:1902966)
0.0	0.1	GO:0097264	self proteolysis(GO:0097264)
0.0	0.1	GO:0033234	negative regulation of protein sumoylation(GO:0033234)
0.0	0.1	GO:0060836	lymphatic endothelial cell differentiation(GO:0060836)
0.0	0.2	GO:0035879	lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0	0.2	GO:0097284	hepatocyte apoptotic process(GO:0097284)
0.0	0.1	GO:0046628	positive regulation of insulin receptor signaling pathway(GO:0046628)
0.0	0.1	GO:0035336	long-chain fatty-acyl-CoA metabolic process(GO:0035336)
0.0	0.0	GO:0032278	positive regulation of gonadotropin secretion(GO:0032278)
0.0	0.1	GO:0015871	choline transport(GO:0015871)
0.0	0.3	GO:0006491	N-glycan processing(GO:0006491)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.0	GO:0001798	type IIa hypersensitivity(GO:0001794) regulation of type IIa hypersensitivity(GO:0001796) positive regulation of type IIa hypersensitivity(GO:0001798) type II hypersensitivity(GO:0002445) regulation of type II hypersensitivity(GO:0002892) positive regulation of type II hypersensitivity(GO:0002894)
0.0	0.0	GO:0045658	regulation of neutrophil differentiation(GO:0045658)
0.0	0.1	GO:0010994	regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0	0.1	GO:0034239	regulation of macrophage fusion(GO:0034239)
0.0	0.0	GO:0035672	oligopeptide transmembrane transport(GO:0035672)
0.0	0.1	GO:0030718	germ-line stem cell population maintenance(GO:0030718)
0.0	0.0	GO:2000346	negative regulation of hepatocyte proliferation(GO:2000346)
0.0	0.3	GO:0006303	double-strand break repair via nonhomologous end joining(GO:0006303)
0.0	0.0	GO:0071394	cellular response to testosterone stimulus(GO:0071394)
0.0	0.0	GO:0010958	regulation of amino acid import(GO:0010958) regulation of L-arginine import(GO:0010963)
0.0	0.1	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.0	GO:0006067	ethanol metabolic process(GO:0006067) ethanol oxidation(GO:0006069)
0.0	0.0	GO:0061502	early endosome to recycling endosome transport(GO:0061502)
0.0	0.1	GO:1901341	positive regulation of store-operated calcium channel activity(GO:1901341)
0.0	0.0	GO:0034756	regulation of iron ion transport(GO:0034756)
0.0	0.1	GO:0010815	bradykinin catabolic process(GO:0010815)
0.0	0.0	GO:0002826	negative regulation of T-helper 1 type immune response(GO:0002826)
0.0	0.3	GO:0071353	cellular response to interleukin-4(GO:0071353)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.0	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.0	GO:0001692	histamine metabolic process(GO:0001692)
0.0	0.0	GO:2000587	regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0	0.0	GO:0007182	common-partner SMAD protein phosphorylation(GO:0007182)
0.0	0.0	GO:0071335	hair follicle cell proliferation(GO:0071335)
0.0	0.0	GO:0034242	negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0	0.0	GO:1901674	histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.0	0.2	GO:0010569	regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.1	GO:0071578	zinc II ion transmembrane import(GO:0071578)
0.0	0.0	GO:0060431	primary lung bud formation(GO:0060431)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:1904729	regulation of intestinal absorption(GO:1904478) regulation of intestinal lipid absorption(GO:1904729)
0.0	0.0	GO:0097118	neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0	0.1	GO:0034154	toll-like receptor 7 signaling pathway(GO:0034154)
0.0	0.1	GO:0042921	glucocorticoid receptor signaling pathway(GO:0042921)
0.0	0.0	GO:0060478	acrosomal vesicle exocytosis(GO:0060478)
0.0	0.0	GO:0032488	Cdc42 protein signal transduction(GO:0032488)
0.0	0.0	GO:0009051	pentose-phosphate shunt, oxidative branch(GO:0009051)
0.0	0.2	GO:0031954	positive regulation of protein autophosphorylation(GO:0031954)
0.0	0.0	GO:0002215	defense response to nematode(GO:0002215)
0.0	0.2	GO:0034243	regulation of transcription elongation from RNA polymerase II promoter(GO:0034243)
0.0	0.1	GO:0060501	positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0	0.0	GO:0060502	epithelial cell proliferation involved in lung morphogenesis(GO:0060502)
0.0	0.0	GO:0046498	S-adenosylhomocysteine metabolic process(GO:0046498)
0.0	0.1	GO:1903671	negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) negative regulation of sprouting angiogenesis(GO:1903671)
0.0	0.1	GO:1900122	positive regulation of receptor binding(GO:1900122)
0.0	0.0	GO:0042138	meiotic DNA double-strand break formation(GO:0042138)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.5	GO:0042587	glycogen granule(GO:0042587)
0.1	0.2	GO:0035339	SPOTS complex(GO:0035339)
0.1	0.3	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.2	GO:0042406	extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0	0.3	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.0	0.3	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.2	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.1	GO:0000214	tRNA-intron endonuclease complex(GO:0000214)
0.0	0.1	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.0	0.1	GO:0033596	TSC1-TSC2 complex(GO:0033596)
0.0	0.1	GO:0042825	TAP complex(GO:0042825)
0.0	0.3	GO:0034663	endoplasmic reticulum chaperone complex(GO:0034663)
0.0	0.1	GO:0042765	GPI-anchor transamidase complex(GO:0042765)
0.0	0.1	GO:0071204	histone pre-mRNA 3'end processing complex(GO:0071204)
0.0	0.1	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0070937	CRD-mediated mRNA stability complex(GO:0070937)
0.0	0.3	GO:0070852	cell body fiber(GO:0070852)
0.0	0.3	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.1	GO:0030127	COPII vesicle coat(GO:0030127)
0.0	0.1	GO:0089701	U2AF(GO:0089701)
0.0	0.1	GO:0030008	TRAPP complex(GO:0030008)
0.0	0.1	GO:0030689	Noc complex(GO:0030689)
0.0	0.2	GO:1990023	mitotic spindle midzone(GO:1990023)
0.0	0.1	GO:0000276	mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0	0.6	GO:0000791	euchromatin(GO:0000791)
0.0	0.2	GO:0071004	U2-type prespliceosome(GO:0071004)
0.0	0.1	GO:0097651	phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0031265	CD95 death-inducing signaling complex(GO:0031265)
0.0	0.2	GO:0098533	ATPase dependent transmembrane transport complex(GO:0098533)
0.0	0.1	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0005964	phosphorylase kinase complex(GO:0005964)
0.0	0.1	GO:0097208	alveolar lamellar body(GO:0097208)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	0.1	GO:1990454	L-type voltage-gated calcium channel complex(GO:1990454)
0.0	0.1	GO:0044294	dendritic growth cone(GO:0044294)
0.0	0.1	GO:0000836	ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0	0.1	GO:0070876	SOSS complex(GO:0070876)
0.0	0.1	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.1	GO:0005832	chaperonin-containing T-complex(GO:0005832)
0.0	0.0	GO:0048179	activin receptor complex(GO:0048179)
0.0	0.2	GO:0043240	Fanconi anaemia nuclear complex(GO:0043240)
0.0	0.0	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0	0.1	GO:0031616	spindle pole centrosome(GO:0031616)
0.0	0.0	GO:0032541	cortical endoplasmic reticulum(GO:0032541)
0.0	0.0	GO:0070688	MLL5-L complex(GO:0070688)
0.0	0.1	GO:0070578	RISC-loading complex(GO:0070578)
0.0	0.1	GO:0030914	STAGA complex(GO:0030914)
0.0	0.1	GO:0033588	Elongator holoenzyme complex(GO:0033588)
0.0	0.0	GO:0005610	laminin-5 complex(GO:0005610)
0.0	0.0	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.0	0.0	GO:0042585	germinal vesicle(GO:0042585)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0004771	sterol esterase activity(GO:0004771)
0.1	0.4	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.4	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.4	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	0.3	GO:0051718	DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1	0.3	GO:0043891	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.1	0.2	GO:0050816	phosphothreonine binding(GO:0050816)
0.1	0.2	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1	0.2	GO:0055100	adiponectin binding(GO:0055100)
0.1	0.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.2	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.1	0.2	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1	0.2	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.4	GO:0003854	3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0	0.1	GO:0004886	9-cis retinoic acid receptor activity(GO:0004886)
0.0	0.5	GO:0008195	phosphatidate phosphatase activity(GO:0008195)
0.0	0.1	GO:0004103	choline kinase activity(GO:0004103)
0.0	0.4	GO:0001091	RNA polymerase II basal transcription factor binding(GO:0001091)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.2	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0046979	TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0	0.2	GO:0016812	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0	0.1	GO:0080130	L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0	0.1	GO:0005006	epidermal growth factor-activated receptor activity(GO:0005006)
0.0	0.1	GO:1901612	cardiolipin binding(GO:1901612)
0.0	0.2	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0043515	kinetochore binding(GO:0043515)
0.0	0.2	GO:0015093	ferrous iron transmembrane transporter activity(GO:0015093)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.3	GO:0035613	RNA stem-loop binding(GO:0035613)
0.0	0.1	GO:0000213	tRNA-intron endonuclease activity(GO:0000213)
0.0	0.1	GO:0098821	BMP receptor activity(GO:0098821)
0.0	0.1	GO:0035939	microsatellite binding(GO:0035939)
0.0	0.5	GO:0004602	glutathione peroxidase activity(GO:0004602)
0.0	0.2	GO:0004439	phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0	0.1	GO:0050508	glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.2	GO:0046624	sphingolipid transporter activity(GO:0046624)
0.0	0.1	GO:0015173	aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0	0.1	GO:0038132	neuregulin binding(GO:0038132)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.2	GO:0016861	intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0	0.1	GO:0015220	choline transmembrane transporter activity(GO:0015220)
0.0	0.2	GO:0102391	decanoate--CoA ligase activity(GO:0102391)
0.0	0.1	GO:0005146	leukemia inhibitory factor receptor binding(GO:0005146)
0.0	0.0	GO:0070546	L-phenylalanine aminotransferase activity(GO:0070546)
0.0	0.1	GO:0070878	primary miRNA binding(GO:0070878)
0.0	0.2	GO:0004571	mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0	0.1	GO:0050252	retinol O-fatty-acyltransferase activity(GO:0050252)
0.0	0.2	GO:0043733	alkylbase DNA N-glycosylase activity(GO:0003905) DNA-3-methylbase glycosylase activity(GO:0043733)
0.0	0.1	GO:0048403	brain-derived neurotrophic factor binding(GO:0048403)
0.0	0.1	GO:0030274	LIM domain binding(GO:0030274)
0.0	0.3	GO:0070064	proline-rich region binding(GO:0070064)
0.0	0.2	GO:0004312	fatty acid synthase activity(GO:0004312)
0.0	0.1	GO:0004449	isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0	0.1	GO:0097200	cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0	0.1	GO:0015562	efflux transmembrane transporter activity(GO:0015562)
0.0	0.1	GO:0036042	long-chain fatty acyl-CoA binding(GO:0036042)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.1	GO:0000293	ferric-chelate reductase activity(GO:0000293)
0.0	0.1	GO:0019961	interferon binding(GO:0019961)
0.0	0.5	GO:0070888	E-box binding(GO:0070888)
0.0	0.1	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0008240	tripeptidyl-peptidase activity(GO:0008240)
0.0	0.1	GO:0034046	poly(G) binding(GO:0034046)
0.0	0.3	GO:0008139	nuclear localization sequence binding(GO:0008139)
0.0	0.2	GO:0015129	lactate transmembrane transporter activity(GO:0015129)
0.0	0.0	GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0	0.1	GO:0004689	phosphorylase kinase activity(GO:0004689)
0.0	0.3	GO:0003746	translation elongation factor activity(GO:0003746)
0.0	0.2	GO:0001223	transcription coactivator binding(GO:0001223)
0.0	0.0	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0	0.3	GO:0071949	FAD binding(GO:0071949)
0.0	0.1	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.0	0.2	GO:0019789	SUMO transferase activity(GO:0019789)
0.0	0.3	GO:0004181	metallocarboxypeptidase activity(GO:0004181)
0.0	0.1	GO:0016453	acetyl-CoA C-acetyltransferase activity(GO:0003985) C-acetyltransferase activity(GO:0016453)
0.0	0.0	GO:0004359	glutaminase activity(GO:0004359)
0.0	0.1	GO:0036374	gamma-glutamyltransferase activity(GO:0003840) glutathione hydrolase activity(GO:0036374)
0.0	0.1	GO:0031782	melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.0	0.1	GO:0035671	enone reductase activity(GO:0035671)
0.0	0.1	GO:0001055	RNA polymerase II activity(GO:0001055)
0.0	0.2	GO:0016500	protein-hormone receptor activity(GO:0016500)
0.0	0.1	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.1	GO:0043995	histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0	0.1	GO:0004064	arylesterase activity(GO:0004064)
0.0	0.0	GO:0017002	activin-activated receptor activity(GO:0017002)
0.0	0.1	GO:0050897	cobalt ion binding(GO:0050897)
0.0	0.1	GO:0017150	tRNA dihydrouridine synthase activity(GO:0017150)
0.0	0.1	GO:0016662	oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662)
0.0	0.0	GO:0008321	Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0	0.0	GO:0004505	phenylalanine 4-monooxygenase activity(GO:0004505)
0.0	0.0	GO:0052622	4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623)
0.0	0.1	GO:0016151	nickel cation binding(GO:0016151)
0.0	0.1	GO:0017040	ceramidase activity(GO:0017040)
0.0	0.2	GO:0090599	alpha-glucosidase activity(GO:0090599)
0.0	0.1	GO:0051787	misfolded protein binding(GO:0051787)
0.0	0.0	GO:0019862	IgA binding(GO:0019862)
0.0	0.1	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0002094	polyprenyltransferase activity(GO:0002094)
0.0	0.2	GO:0005070	SH3/SH2 adaptor activity(GO:0005070)
0.0	0.0	GO:0098748	clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0	0.1	GO:0050811	GABA receptor binding(GO:0050811)
0.0	0.0	GO:0102345	3-hydroxy-behenoyl-CoA dehydratase activity(GO:0102344) 3-hydroxy-lignoceroyl-CoA dehydratase activity(GO:0102345)
0.0	0.0	GO:0031852	mu-type opioid receptor binding(GO:0031852)
0.0	0.1	GO:0045322	unmethylated CpG binding(GO:0045322)
0.0	0.1	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.0	GO:0003987	acetate-CoA ligase activity(GO:0003987)
0.0	0.1	GO:0002054	nucleobase binding(GO:0002054)
0.0	0.0	GO:0001226	RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.0	0.1	GO:0045295	gamma-catenin binding(GO:0045295)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.1	ST JAK STAT PATHWAY	Jak-STAT Pathway
0.3	PID DNA PK PATHWAY	DNA-PK pathway in nonhomologous end joining
0.2	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.3	PID HDAC CLASSIII PATHWAY	Signaling events mediated by HDAC Class III
0.2	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.5	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	PID IGF1 PATHWAY	IGF1 pathway
0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.
0.3	PID MYC PATHWAY	C-MYC pathway
0.2	PID P38 MK2 PATHWAY	p38 signaling mediated by MAPKAP kinases

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.6	REACTOME SYNTHESIS OF PE	Genes involved in Synthesis of PE
0.1	0.5	REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL	Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0	0.3	REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA	Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0	0.4	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.2	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.0	0.3	REACTOME COPI MEDIATED TRANSPORT	Genes involved in COPI Mediated Transport
0.0	0.6	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0	0.3	REACTOME FATTY ACYL COA BIOSYNTHESIS	Genes involved in Fatty Acyl-CoA Biosynthesis
0.0	0.1	REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0	0.1	REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK	Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0	0.1	REACTOME CALNEXIN CALRETICULIN CYCLE	Genes involved in Calnexin/calreticulin cycle
0.0	0.3	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.2	REACTOME PURINE SALVAGE	Genes involved in Purine salvage
0.0	0.2	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.1	REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON	Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0	0.1	REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING	Genes involved in Formation of ATP by chemiosmotic coupling
0.0	0.3	REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS	Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0	0.3	REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS	Genes involved in Sphingolipid de novo biosynthesis
0.0	0.1	REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS	Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0	0.0	REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE	Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0	0.1	REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING	Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.1	REACTOME SOS MEDIATED SIGNALLING	Genes involved in SOS-mediated signalling
0.0	0.2	REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS	Genes involved in Regulation of gene expression in beta cells
0.0	0.2	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane