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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Zfp652

Z-value: 2.50

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Transcription factors associated with Zfp652

Gene Symbol	Gene ID	Gene Info
Zfp652 Ensembl NCBI MGI UniProt	ENSMUSG00000075595.3	Zfp652

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

Gene	Promoter	Distance	Association probability	Pearson corr. coef.	P-value	Plot
Zfp652	chr11_95709774_95709938	2817	0.168699	-0.99	5.4e-05	Click!
Zfp652	chr11_95724615_95724802	11697	0.122172	-0.98	8.2e-04	Click!
Zfp652	chr11_95719434_95719596	6504	0.132014	-0.97	1.7e-03	Click!
Zfp652	chr11_95709547_95709712	3044	0.162612	-0.90	1.3e-02	Click!
Zfp652	chr11_95750632_95750819	1658	0.272858	0.86	3.0e-02	Click!

Activity of the Zfp652 motif across conditions

Conditions sorted by the z-value of the Zfp652 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr1_51751367_51751637	4.22	Gm28055	predicted gene 28055	4559	0.23
chrX_11997001_11997158	3.42	Gm14512	predicted gene 14512	12611	0.24
chr1_21259122_21259550	2.62	Gsta3	glutathione S-transferase, alpha 3	5815	0.12
chr8_110644559_110644860	2.53	Vac14	Vac14 homolog (S. cerevisiae)	871	0.63
chr17_80022007_80022158	2.33	Gm22215	predicted gene, 22215	11432	0.14
chr9_44087724_44088170	2.21	Usp2	ubiquitin specific peptidase 2	757	0.37
chr1_188902459_188902627	2.02	Ush2a	usherin	51201	0.15
chr14_17823512_17823678	1.98	Gm48320	predicted gene, 48320	52473	0.16
chr1_21262098_21262745	1.93	Gsta3	glutathione S-transferase, alpha 3	8900	0.11
chr8_104787830_104787982	1.88	Gm45782	predicted gene 45782	2078	0.17
chr3_89338031_89338206	1.78	Efna4	ephrin A4	90	0.7
chr3_133726266_133726417	1.77	Gm40153	predicted gene, 40153	62950	0.1
chr4_121078016_121078199	1.76	Zmpste24	zinc metallopeptidase, STE24	369	0.74
chr11_77663952_77664103	1.74	Gm23132	predicted gene, 23132	5320	0.13
chr1_21299781_21300307	1.69	Gm4956	predicted gene 4956	1732	0.22
chr10_68126914_68127100	1.69	Arid5b	AT rich interactive domain 5B (MRF1-like)	9619	0.25
chr11_105353735_105353899	1.65	Gm11638	predicted gene 11638	9435	0.17
chr9_35175169_35175403	1.60	Dcps	decapping enzyme, scavenger	707	0.52
chr4_47366562_47366857	1.60	Tgfbr1	transforming growth factor, beta receptor I	13099	0.22
chr11_16826830_16827159	1.60	Egfros	epidermal growth factor receptor, opposite strand	3708	0.27
chr19_26823641_26823967	1.60	4931403E22Rik	RIKEN cDNA 4931403E22 gene	103	0.97
chr1_132476574_132476725	1.58	6030442K20Rik	RIKEN cDNA 6030442K20 gene	396	0.63
chr6_94653423_94653689	1.56	Lrig1	leucine-rich repeats and immunoglobulin-like domains 1	1969	0.38
chr9_68957886_68958054	1.54	Rora	RAR-related orphan receptor alpha	237571	0.02
chr15_88919761_88919917	1.54	Ttll8	tubulin tyrosine ligase-like family, member 8	29	0.97
chr19_40138748_40138899	1.46	Cyp2c70	cytochrome P450, family 2, subfamily c, polypeptide 70	48463	0.1
chr6_6149940_6150263	1.35	Slc25a13	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13	23850	0.23
chr2_58785851_58786309	1.31	Upp2	uridine phosphorylase 2	20755	0.19
chr8_68082402_68082553	1.30	Psd3	pleckstrin and Sec7 domain containing 3	20191	0.24
chr2_118532811_118533170	1.28	Bmf	BCL2 modifying factor	11597	0.16
chr5_92524378_92524560	1.24	Scarb2	scavenger receptor class B, member 2	17636	0.15
chr19_38399310_38399568	1.23	Slc35g1	solute carrier family 35, member G1	3398	0.2
chr8_36242947_36243098	1.20	Lonrf1	LON peptidase N-terminal domain and ring finger 1	6494	0.21
chr1_177711335_177711718	1.14	1700016C15Rik	RIKEN cDNA 1700016C15 gene	18288	0.18
chr3_83048403_83048757	1.12	Fgb	fibrinogen beta chain	1283	0.37
chr17_63195864_63196015	1.07	Gm24730	predicted gene, 24730	6799	0.29
chr2_134534653_134534804	1.06	Hao1	hydroxyacid oxidase 1, liver	19579	0.27
chr14_78536823_78537132	1.06	Akap11	A kinase (PRKA) anchor protein 11	169	0.96
chr4_82476051_82476238	1.05	Nfib	nuclear factor I/B	23172	0.18
chr6_95936843_95937045	1.05	Gm7838	predicted gene 7838	10015	0.29
chr9_105792087_105792238	1.05	Col6a6	collagen, type VI, alpha 6	17486	0.2
chr4_106939076_106939227	1.03	Ssbp3	single-stranded DNA binding protein 3	2547	0.3
chr6_137754656_137754862	1.02	Dera	deoxyribose-phosphate aldolase (putative)	144	0.97
chr10_69584810_69585026	1.00	Gm46231	predicted gene, 46231	18557	0.24
chr17_46026823_46026974	0.97	Vegfa	vascular endothelial growth factor A	2017	0.29
chr19_7477624_7477775	0.97	Rtn3	reticulon 3	5503	0.15
chr1_74695935_74696104	0.95	Ttll4	tubulin tyrosine ligase-like family, member 4	285	0.87
chr18_5141716_5141913	0.93	Gm26682	predicted gene, 26682	23917	0.21
chr4_116673334_116673488	0.93	Gm25137	predicted gene, 25137	742	0.5
chr9_64814123_64814281	0.91	Dennd4a	DENN/MADD domain containing 4A	2658	0.3
chr3_52648763_52649088	0.91	Gm10293	predicted pseudogene 10293	36090	0.17
chr8_94871189_94871343	0.90	Dok4	docking protein 4	62	0.95
chr3_118444081_118444268	0.90	Gm9916	predicted gene 9916	9404	0.15
chr12_80932956_80933128	0.88	1700052I22Rik	RIKEN cDNA 1700052I22 gene	8593	0.13
chr1_85105794_85106219	0.87	A530040E14Rik	RIKEN cDNA A530040E14 gene	60	0.94
chr5_31494357_31494508	0.87	Gpn1	GPN-loop GTPase 1	309	0.68
chr19_5460289_5460467	0.86	Fibp	fibroblast growth factor (acidic) intracellular binding protein	237	0.74
chr4_141870823_141871025	0.86	Efhd2	EF hand domain containing 2	3996	0.12
chr11_113140051_113140245	0.85	2610035D17Rik	RIKEN cDNA 2610035D17 gene	32929	0.22
chr8_90947382_90947547	0.85	Chd9	chromodomain helicase DNA binding protein 9	7494	0.17
chr9_45918008_45918198	0.84	Pcsk7	proprotein convertase subtilisin/kexin type 7	490	0.62
chr4_3373410_3373589	0.82	Gm11784	predicted gene 11784	13347	0.2
chr2_94177720_94177917	0.80	Mir670hg	MIR670 host gene (non-protein coding)	1097	0.45
chr19_40341299_40341486	0.78	Sorbs1	sorbin and SH3 domain containing 1	798	0.65
chr8_108767561_108767755	0.77	Gm38042	predicted gene, 38042	30065	0.2
chr1_67149336_67150363	0.77	Cps1	carbamoyl-phosphate synthetase 1	26823	0.2
chr1_67197806_67198015	0.77	Gm15668	predicted gene 15668	51290	0.13
chr18_38754897_38755064	0.76	Gm8302	predicted gene 8302	17367	0.16
chr13_109485029_109485208	0.75	Pde4d	phosphodiesterase 4D, cAMP specific	42935	0.21
chr13_94806502_94806690	0.74	Tbca	tubulin cofactor A	11138	0.19
chr1_36090124_36090556	0.74	Hs6st1	heparan sulfate 6-O-sulfotransferase 1	11350	0.13
chr10_7793023_7793376	0.74	Ppil4	peptidylprolyl isomerase (cyclophilin)-like 4	278	0.56
chr1_133103203_133103354	0.72	Ppp1r15b	protein phosphatase 1, regulatory subunit 15B	27865	0.11
chr4_148617730_148618042	0.71	Tardbp	TAR DNA binding protein	34	0.96
chr18_64009773_64009965	0.71	Gm6974	predicted gene 6974	71551	0.1
chr3_36533351_36533502	0.70	Gm11549	predicted gene 11549	1042	0.38
chr8_13140413_13140571	0.70	Cul4a	cullin 4A	185	0.89
chr11_98960264_98960733	0.69	Rara	retinoic acid receptor, alpha	86	0.94
chr11_112055735_112055912	0.68	Gm11679	predicted gene 11679	12245	0.27
chr13_119389612_119389948	0.67	Nnt	nicotinamide nucleotide transhydrogenase	19172	0.17
chr3_52270975_52271214	0.67	Gm20402	predicted gene 20402	1659	0.26
chr10_93094773_93094963	0.66	Gm32468	predicted gene, 32468	9617	0.2
chr7_45127479_45128111	0.66	Rpl13a	ribosomal protein L13A	28	0.71
chr15_85750165_85750444	0.66	Ppara	peroxisome proliferator activated receptor alpha	14173	0.14
chr19_55107598_55107749	0.66	Gpam	glycerol-3-phosphate acyltransferase, mitochondrial	4582	0.23
chr11_75049810_75049987	0.64	Gm12333	predicted gene 12333	10550	0.12
chr4_48272049_48272240	0.64	Erp44	endoplasmic reticulum protein 44	7308	0.2
chr1_190137352_190137664	0.64	Gm28172	predicted gene 28172	31162	0.16
chr14_21435070_21435221	0.62	Gm25864	predicted gene, 25864	15329	0.19
chr11_46697157_46697317	0.61	Timd2	T cell immunoglobulin and mucin domain containing 2	1725	0.3
chr1_146494374_146494981	0.61	Brinp3	bone morphogenetic protein/retinoic acid inducible neural specific 3	83	0.75
chr3_102409696_102409850	0.61	Gm43245	predicted gene 43245	19766	0.17
chr8_94966654_94966820	0.59	Gm10286	predicted gene 10286	3017	0.16
chr1_91458255_91458771	0.59	Per2	period circadian clock 2	811	0.48
chr7_140828126_140828283	0.58	Zfp941	zinc finger protein 941	6026	0.07
chr18_16774605_16774780	0.58	Cdh2	cadherin 2	33770	0.16
chr4_62699191_62699363	0.58	Rgs3	regulator of G-protein signaling 3	189	0.94
chr14_105730837_105730988	0.57	Gm10076	predicted gene 10076	49083	0.13
chr16_93823192_93823406	0.57	Morc3	microrchidia 3	8822	0.13
chrX_52163913_52164117	0.56	Gpc4	glypican 4	1237	0.61
chr2_5368187_5368380	0.56	Gm13197	predicted gene 13197	84633	0.09
chr15_59540480_59540643	0.55	Gm36677	predicted gene, 36677	78029	0.09
chr2_90504412_90504563	0.55	4933423P22Rik	RIKEN cDNA 4933423P22 gene	25237	0.16
chr19_55743466_55744137	0.55	Tcf7l2	transcription factor 7 like 2, T cell specific, HMG box	956	0.7
chr3_27863709_27863878	0.55	Gm26040	predicted gene, 26040	4320	0.27
chr15_64382862_64383209	0.54	Asap1	ArfGAP with SH3 domain, ankyrin repeat and PH domain1	116	0.97
chr17_84972486_84972668	0.54	Ppm1b	protein phosphatase 1B, magnesium dependent, beta isoform	7544	0.18
chr17_17827607_17827918	0.53	Spaca6	sperm acrosome associated 6	438	0.64
chr17_48001818_48001969	0.53	Gm14871	predicted gene 14871	1679	0.3
chrX_130754421_130754819	0.52	Gm26209	predicted gene, 26209	133158	0.05
chr1_165464701_165464879	0.52	Gm37860	predicted gene, 37860	2710	0.13
chr1_21267061_21267212	0.52	Gm28836	predicted gene 28836	4457	0.12
chr19_25622028_25622403	0.51	Dmrt3	doublesex and mab-3 related transcription factor 3	11678	0.21
chr2_27694949_27695100	0.51	Rxra	retinoid X receptor alpha	14268	0.25
chr3_138288275_138288480	0.50	Adh1	alcohol dehydrogenase 1 (class I)	10726	0.12
chr2_152733626_152733777	0.50	Id1	inhibitor of DNA binding 1, HLH protein	2550	0.16
chr11_85182930_85183081	0.50	1700125H20Rik	RIKEN cDNA 1700125H20 gene	11909	0.13
chr12_85304850_85305043	0.50	Zc2hc1c	zinc finger, C2HC-type containing 1C	16355	0.1
chr3_94365935_94366258	0.49	C2cd4d	C2 calcium-dependent domain containing 4D	3593	0.09
chr17_45594619_45594866	0.49	Slc29a1	solute carrier family 29 (nucleoside transporters), member 1	760	0.44
chr17_28523067_28523337	0.48	Gm20109	predicted gene, 20109	54	0.53
chr17_57211088_57211386	0.48	Mir6978	microRNA 6978	5991	0.11
chr6_29828721_29828890	0.47	Ahcyl2	S-adenosylhomocysteine hydrolase-like 2	24955	0.16
chr4_130721540_130721691	0.47	Snord85	small nucleolar RNA, C/D box 85	28019	0.12
chr16_56279382_56279563	0.47	Impg2	interphotoreceptor matrix proteoglycan 2	9288	0.23
chr8_33918433_33918601	0.46	Rbpms	RNA binding protein gene with multiple splicing	10759	0.17
chr4_137795539_137795761	0.45	Alpl	alkaline phosphatase, liver/bone/kidney	580	0.78
chr14_36973905_36974284	0.45	Ccser2	coiled-coil serine rich 2	5317	0.22
chr8_126969660_126969828	0.45	Rbm34	RNA binding motif protein 34	1305	0.37
chr15_79321473_79321634	0.45	Pla2g6	phospholipase A2, group VI	2013	0.19
chr4_133042632_133042816	0.45	Ahdc1	AT hook, DNA binding motif, containing 1	3231	0.25
chr11_75568775_75568947	0.45	Slc43a2	solute carrier family 43, member 2	2045	0.17
chr2_134845241_134845392	0.44	Gm14036	predicted gene 14036	41367	0.17
chr2_158038644_158038816	0.43	Rprd1b	regulation of nuclear pre-mRNA domain containing 1B	4693	0.19
chr12_54655761_54656415	0.43	Sptssa	serine palmitoyltransferase, small subunit A	110	0.91
chr4_70482987_70483163	0.42	Megf9	multiple EGF-like-domains 9	51853	0.17
chr8_111535997_111536473	0.42	Znrf1	zinc and ring finger 1	138	0.96
chr8_41019347_41019768	0.42	B430010I23Rik	RIKEN cDNA B430010I23 gene	1819	0.27
chr11_16905052_16905224	0.41	Egfr	epidermal growth factor receptor	47	0.98
chr11_75297718_75298001	0.41	Gm47300	predicted gene, 47300	20749	0.13
chr7_25280357_25280508	0.41	Cic	capicua transcriptional repressor	791	0.41
chr15_81343404_81343586	0.41	Slc25a17	solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17	662	0.64
chr4_35126863_35127042	0.41	Ifnk	interferon kappa	25104	0.16
chr5_124351456_124351859	0.40	Cdk2ap1	CDK2 (cyclin-dependent kinase 2)-associated protein 1	3	0.96
chr16_13354242_13354407	0.40	Mrtfb	myocardin related transcription factor B	4097	0.25
chr10_75516024_75516215	0.40	Gucd1	guanylyl cyclase domain containing 1	1051	0.33
chr17_26724491_26724642	0.39	Crebrf	CREB3 regulatory factor	8842	0.16
chr10_23851933_23852432	0.39	Vnn3	vanin 3	720	0.56
chr18_12075776_12075953	0.39	Tmem241	transmembrane protein 241	1233	0.51
chr3_148680566_148680729	0.39	Gm43575	predicted gene 43575	27587	0.24
chr13_48543479_48543831	0.39	Gm37238	predicted gene, 37238	1378	0.22
chr13_89551647_89551801	0.39	Hapln1	hyaluronan and proteoglycan link protein 1	11928	0.23
chr6_121138262_121138418	0.39	Mical3	microtubule associated monooxygenase, calponin and LIM domain containing 3	7341	0.15
chr2_6379003_6379169	0.39	Usp6nl	USP6 N-terminal like	26353	0.17
chr4_84068033_84068731	0.38	6030471H07Rik	RIKEN cDNA 6030471H07 gene	23503	0.2
chr11_98729103_98729272	0.38	Med24	mediator complex subunit 24	180	0.89
chr12_87444275_87444437	0.38	Alkbh1	alkB homolog 1, histone H2A dioxygenase	339	0.47
chr4_76435923_76436234	0.36	Ptprd	protein tyrosine phosphatase, receptor type, D	13902	0.21
chr5_108660752_108661377	0.36	Dgkq	diacylglycerol kinase, theta	253	0.76
chr4_104765968_104766173	0.36	C8b	complement component 8, beta polypeptide	247	0.95
chr13_95859199_95859350	0.35	Iqgap2	IQ motif containing GTPase activating protein 2	32483	0.16
chr15_57980598_57980801	0.35	Fam83a	family with sequence similarity 83, member A	4720	0.19
chr10_62924201_62924495	0.35	Gm25862	predicted gene, 25862	824	0.43
chr7_44384509_44384671	0.35	Syt3	synaptotagmin III	14	0.92
chr9_44479696_44479909	0.35	Gm47204	predicted gene, 47204	43	0.9
chr15_83202527_83202771	0.35	7530414M10Rik	RIKEN cDNA 7530414M10 gene	26204	0.1
chr19_40299087_40299297	0.35	Sorbs1	sorbin and SH3 domain containing 1	634	0.57
chr14_16573464_16573628	0.34	Rarb	retinoic acid receptor, beta	1499	0.4
chr10_20723259_20723681	0.34	Pde7b	phosphodiesterase 7B	1226	0.53
chr5_146239026_146239445	0.34	Cdk8	cyclin-dependent kinase 8	7850	0.12
chr17_26589554_26589705	0.34	Ergic1	endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1	5247	0.13
chr13_38527580_38527738	0.34	Txndc5	thioredoxin domain containing 5	255	0.47
chr19_18146304_18146531	0.34	Gm18610	predicted gene, 18610	59378	0.14
chr4_102811326_102811477	0.34	Sgip1	SH3-domain GRB2-like (endophilin) interacting protein 1	50876	0.15
chr18_74764829_74765043	0.33	Scarna17	small Cajal body-specific RNA 17	13533	0.14
chr12_101766870_101767053	0.33	Tc2n	tandem C2 domains, nuclear	48438	0.12
chr2_116983226_116983382	0.33	Gm29340	predicted gene 29340	6876	0.2
chr7_127614456_127614767	0.33	Zfp629	zinc finger protein 629	178	0.86
chr2_167348215_167348655	0.33	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5	748	0.67
chr16_36935496_36935647	0.32	Hcls1	hematopoietic cell specific Lyn substrate 1	588	0.62
chr9_119308875_119309095	0.32	Gm22729	predicted gene, 22729	2228	0.21
chr11_98796894_98797678	0.32	Msl1	male specific lethal 1	1368	0.26
chr11_77661061_77661234	0.32	Gm23132	predicted gene, 23132	2440	0.19
chr6_124541506_124541699	0.32	C1s1	complement component 1, s subcomponent 1	701	0.5
chr6_137738154_137738336	0.31	Strap	serine/threonine kinase receptor associated protein	3167	0.29
chr10_9009141_9009301	0.30	Gm48728	predicted gene, 48728	57272	0.12
chr11_34181831_34182010	0.30	Foxi1	forkhead box I1	26169	0.16
chr13_48540722_48541023	0.30	Mirlet7a-1	microRNA let7a-1	2600	0.12
chr8_117737291_117737442	0.30	Gm31774	predicted gene, 31774	10894	0.14
chr7_119847929_119848089	0.29	Rexo5	RNA exonuclease 5	3803	0.17
chr11_119577189_119577358	0.29	Rptor	regulatory associated protein of MTOR, complex 1	25632	0.13
chr18_80294645_80295296	0.29	Gm37015	predicted gene, 37015	8710	0.13
chr6_36175492_36175671	0.29	Gm43443	predicted gene 43443	13518	0.28
chr7_3073209_3073392	0.29	Gm3104	predicted gene 3104	12701	0.1
chr1_151132224_151132407	0.29	Gm8941	predicted gene 8941	4192	0.14
chr4_82447093_82447266	0.29	n-R5s188	nuclear encoded rRNA 5S 188	7769	0.24
chr1_64533839_64534218	0.28	Creb1	cAMP responsive element binding protein 1	1134	0.54
chr6_72117206_72117587	0.28	St3gal5	ST3 beta-galactoside alpha-2,3-sialyltransferase 5	2164	0.2
chr5_64506002_64506172	0.28	C030018K13Rik	RIKEN cDNA C030018K13 gene	29052	0.1
chr4_152229764_152230378	0.28	Gm13096	predicted gene 13096	26145	0.1

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfp652

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.5	1.5	GO:0018094	protein polyglycylation(GO:0018094)
0.4	1.3	GO:0030327	prenylated protein catabolic process(GO:0030327)
0.3	1.1	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.2	0.6	GO:1903800	positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.2	0.6	GO:0032474	otolith morphogenesis(GO:0032474)
0.2	0.5	GO:0043152	induction of bacterial agglutination(GO:0043152)
0.2	0.6	GO:0060591	chondroblast differentiation(GO:0060591)
0.1	0.5	GO:0048619	embryonic hindgut morphogenesis(GO:0048619)
0.1	0.7	GO:0071763	nuclear membrane organization(GO:0071763)
0.1	0.3	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.1	0.8	GO:0018095	protein polyglutamylation(GO:0018095)
0.1	0.3	GO:1901492	positive regulation of lymphangiogenesis(GO:1901492)
0.1	0.3	GO:0006768	biotin metabolic process(GO:0006768)
0.1	0.8	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1	0.2	GO:1990034	calcium ion export from cell(GO:1990034)
0.1	0.2	GO:0065001	specification of axis polarity(GO:0065001)
0.1	0.5	GO:0060605	tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.1	0.7	GO:0030853	negative regulation of granulocyte differentiation(GO:0030853)
0.1	0.3	GO:0090135	actin filament branching(GO:0090135)
0.1	0.2	GO:1901844	regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1	0.4	GO:0045602	negative regulation of endothelial cell differentiation(GO:0045602)
0.1	0.4	GO:0034310	primary alcohol catabolic process(GO:0034310)
0.1	0.4	GO:0060613	fat pad development(GO:0060613)
0.1	0.3	GO:0048496	maintenance of organ identity(GO:0048496)
0.1	0.2	GO:0097105	presynaptic membrane assembly(GO:0097105)
0.1	0.3	GO:0015867	ATP transport(GO:0015867)
0.1	0.2	GO:0032910	transforming growth factor beta3 production(GO:0032907) regulation of transforming growth factor beta3 production(GO:0032910)
0.1	0.6	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.1	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0	0.9	GO:0010738	regulation of protein kinase A signaling(GO:0010738)
0.0	0.7	GO:0045725	positive regulation of glycogen biosynthetic process(GO:0045725)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:0014722	regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.0	0.5	GO:0001731	formation of translation preinitiation complex(GO:0001731)
0.0	0.1	GO:1901631	positive regulation of presynaptic membrane organization(GO:1901631) positive regulation of synaptic vesicle clustering(GO:2000809)
0.0	0.2	GO:0042663	regulation of endodermal cell fate specification(GO:0042663)
0.0	0.3	GO:0021999	neural plate anterior/posterior regionalization(GO:0021999)
0.0	1.7	GO:0043550	regulation of lipid kinase activity(GO:0043550)
0.0	0.3	GO:0019856	'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0	0.1	GO:0060978	angiogenesis involved in coronary vascular morphogenesis(GO:0060978)
0.0	0.1	GO:0051182	coenzyme transport(GO:0051182)
0.0	0.7	GO:0045475	locomotor rhythm(GO:0045475)
0.0	0.4	GO:0070493	thrombin receptor signaling pathway(GO:0070493)
0.0	0.1	GO:0034137	positive regulation of toll-like receptor 2 signaling pathway(GO:0034137)
0.0	0.3	GO:0060710	chorio-allantoic fusion(GO:0060710)
0.0	0.5	GO:0061000	negative regulation of dendritic spine development(GO:0061000)
0.0	0.3	GO:0031340	positive regulation of vesicle fusion(GO:0031340)
0.0	0.2	GO:0070837	dehydroascorbic acid transport(GO:0070837)
0.0	0.2	GO:0070236	negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0	0.2	GO:0048133	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0	0.1	GO:0055005	ventricular cardiac myofibril assembly(GO:0055005)
0.0	0.2	GO:0070989	oxidative demethylation(GO:0070989)
0.0	0.1	GO:0060971	embryonic heart tube left/right pattern formation(GO:0060971)
0.0	0.1	GO:0006533	aspartate catabolic process(GO:0006533)
0.0	0.1	GO:0007023	post-chaperonin tubulin folding pathway(GO:0007023)
0.0	1.2	GO:0048013	ephrin receptor signaling pathway(GO:0048013)
0.0	0.1	GO:0000957	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.1	GO:0002051	osteoblast fate commitment(GO:0002051)
0.0	0.2	GO:0015858	nucleoside transport(GO:0015858)
0.0	0.1	GO:0051295	establishment of meiotic spindle localization(GO:0051295)
0.0	0.2	GO:0045651	positive regulation of macrophage differentiation(GO:0045651)
0.0	0.3	GO:0006957	complement activation, alternative pathway(GO:0006957)
0.0	0.3	GO:0007342	fusion of sperm to egg plasma membrane(GO:0007342)
0.0	0.1	GO:2000304	positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0	0.1	GO:0008050	female courtship behavior(GO:0008050)
0.0	0.1	GO:0036492	regulation of translation in response to endoplasmic reticulum stress(GO:0036490) regulation of translation initiation in response to endoplasmic reticulum stress(GO:0036491) eiF2alpha phosphorylation in response to endoplasmic reticulum stress(GO:0036492)
0.0	0.2	GO:0043651	linoleic acid metabolic process(GO:0043651)
0.0	0.1	GO:0071455	cellular response to increased oxygen levels(GO:0036295) cellular response to hyperoxia(GO:0071455)
0.0	0.1	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.0	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.1	GO:0036092	phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0	0.1	GO:0010796	regulation of multivesicular body size(GO:0010796)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:1900169	regulation of glucocorticoid mediated signaling pathway(GO:1900169)
0.0	0.1	GO:0035526	retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0	0.1	GO:0035696	monocyte extravasation(GO:0035696) regulation of monocyte extravasation(GO:2000437)
0.0	0.1	GO:0006499	N-terminal protein myristoylation(GO:0006499)
0.0	0.3	GO:0032012	ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:1904970	brush border assembly(GO:1904970)
0.0	0.1	GO:1900825	regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0	0.5	GO:0001958	endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.0	0.1	GO:0006167	AMP biosynthetic process(GO:0006167)
0.0	0.1	GO:0032202	telomere assembly(GO:0032202)
0.0	0.1	GO:0009177	deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0	0.1	GO:0033353	S-adenosylmethionine cycle(GO:0033353)
0.0	0.1	GO:0010572	positive regulation of platelet activation(GO:0010572)
0.0	0.0	GO:0075509	receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.0	0.7	GO:0070527	platelet aggregation(GO:0070527)
0.0	0.3	GO:0000413	protein peptidyl-prolyl isomerization(GO:0000413)
0.0	0.0	GO:0030576	Cajal body organization(GO:0030576)
0.0	0.1	GO:0051031	tRNA transport(GO:0051031)
0.0	0.0	GO:0006714	sesquiterpenoid metabolic process(GO:0006714)
0.0	0.1	GO:0070940	dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0	0.2	GO:0006613	cotranslational protein targeting to membrane(GO:0006613)
0.0	0.0	GO:1902109	negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.0	0.0	GO:0014042	positive regulation of neuron maturation(GO:0014042)
0.0	0.0	GO:0034476	U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476) nuclear polyadenylation-dependent mRNA catabolic process(GO:0071042) polyadenylation-dependent mRNA catabolic process(GO:0071047)
0.0	0.2	GO:0097286	iron ion import(GO:0097286)
0.0	0.1	GO:0055012	ventricular cardiac muscle cell differentiation(GO:0055012)
0.0	0.1	GO:0060294	cilium movement involved in cell motility(GO:0060294)
0.0	0.0	GO:0060847	endothelial cell fate specification(GO:0060847)
0.0	0.2	GO:0006622	protein targeting to lysosome(GO:0006622)
0.0	0.4	GO:0071300	cellular response to retinoic acid(GO:0071300)
0.0	0.2	GO:0097031	NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0	0.4	GO:0033120	positive regulation of RNA splicing(GO:0033120)
0.0	0.0	GO:0060681	branch elongation involved in ureteric bud branching(GO:0060681)
0.0	0.0	GO:0061470	T follicular helper cell differentiation(GO:0061470)
0.0	0.0	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0030277	maintenance of gastrointestinal epithelium(GO:0030277)
0.0	0.0	GO:0007227	signal transduction downstream of smoothened(GO:0007227)
0.0	0.3	GO:0030574	collagen catabolic process(GO:0030574)
0.0	0.0	GO:2000338	chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0	0.2	GO:0043276	anoikis(GO:0043276)
0.0	0.0	GO:1990168	protein K29-linked deubiquitination(GO:0035523) protein K33-linked deubiquitination(GO:1990168)
0.0	0.0	GO:0060167	regulation of adenosine receptor signaling pathway(GO:0060167)
0.0	0.5	GO:0046513	ceramide biosynthetic process(GO:0046513)
0.0	0.0	GO:2000467	positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0	0.3	GO:0060325	face morphogenesis(GO:0060325)
0.0	0.0	GO:0016584	nucleosome positioning(GO:0016584)
0.0	0.0	GO:0032439	endosome localization(GO:0032439)
0.0	0.1	GO:0014041	regulation of neuron maturation(GO:0014041)
0.0	0.0	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.0	GO:0072318	clathrin coat disassembly(GO:0072318)
0.0	0.0	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.0	0.6	GO:0045454	cell redox homeostasis(GO:0045454)
0.0	0.1	GO:0060391	positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0	0.0	GO:2000686	regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0	0.0	GO:0035864	response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.0	0.0	GO:0030046	parallel actin filament bundle assembly(GO:0030046)
0.0	0.0	GO:0051665	membrane raft localization(GO:0051665)
0.0	0.1	GO:0044273	sulfur compound catabolic process(GO:0044273)
0.0	0.0	GO:0006688	glycosphingolipid biosynthetic process(GO:0006688)
0.0	0.0	GO:0070345	negative regulation of fat cell proliferation(GO:0070345)
0.0	0.4	GO:0030521	androgen receptor signaling pathway(GO:0030521)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.3	1.6	GO:0035032	phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2	0.7	GO:0005899	insulin receptor complex(GO:0005899)
0.2	0.6	GO:0097487	multivesicular body, internal vesicle(GO:0097487)
0.1	0.4	GO:1990907	beta-catenin-TCF complex(GO:1990907)
0.1	0.5	GO:0097452	GAIT complex(GO:0097452)
0.1	0.6	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1	0.6	GO:0005577	fibrinogen complex(GO:0005577)
0.1	0.3	GO:0002142	stereocilia ankle link complex(GO:0002142)
0.1	0.3	GO:0005579	membrane attack complex(GO:0005579)
0.1	0.2	GO:0031523	Myb complex(GO:0031523)
0.0	0.4	GO:0031211	serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0	0.2	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.2	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.0	0.1	GO:0097513	myosin II filament(GO:0097513)
0.0	0.4	GO:0044666	MLL3/4 complex(GO:0044666)
0.0	0.1	GO:0097543	ciliary inversin compartment(GO:0097543)
0.0	0.8	GO:0032588	trans-Golgi network membrane(GO:0032588)
0.0	0.2	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.2	GO:0043202	lysosomal lumen(GO:0043202)
0.0	0.2	GO:0044300	cerebellar mossy fiber(GO:0044300)
0.0	0.4	GO:0065010	extracellular membrane-bounded organelle(GO:0065010)
0.0	0.2	GO:0042788	polysomal ribosome(GO:0042788)
0.0	0.1	GO:0005785	signal recognition particle receptor complex(GO:0005785)
0.0	0.1	GO:0097451	glial limiting end-foot(GO:0097451)
0.0	0.3	GO:0005779	integral component of peroxisomal membrane(GO:0005779)
0.0	0.3	GO:0034719	SMN-Sm protein complex(GO:0034719)
0.0	0.1	GO:0005594	collagen type IX trimer(GO:0005594)
0.0	1.5	GO:0097014	axoneme(GO:0005930) ciliary plasm(GO:0097014)
0.0	0.1	GO:0005786	signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0	0.1	GO:0071256	Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0	2.3	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.1	GO:0031931	TORC1 complex(GO:0031931)
0.0	0.3	GO:0005719	nuclear euchromatin(GO:0005719)
0.0	0.0	GO:0071953	elastic fiber(GO:0071953)
0.0	0.1	GO:0070187	telosome(GO:0070187)
0.0	0.0	GO:0043293	apoptosome(GO:0043293)
0.0	0.0	GO:0005712	chiasma(GO:0005712)
0.0	0.5	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.1	GO:0016342	catenin complex(GO:0016342)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)
0.0	0.2	GO:0043034	costamere(GO:0043034)
0.0	0.1	GO:0000974	Prp19 complex(GO:0000974)
0.0	0.4	GO:0016592	mediator complex(GO:0016592)
0.0	0.1	GO:0030122	AP-2 adaptor complex(GO:0030122)
0.0	0.1	GO:0044233	ER-mitochondrion membrane contact site(GO:0044233)
0.0	0.1	GO:0060293	P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0048408	epidermal growth factor binding(GO:0048408)
0.2	0.8	GO:0000340	RNA 7-methylguanosine cap binding(GO:0000340)
0.2	0.8	GO:0044323	retinoic acid-responsive element binding(GO:0044323)
0.1	0.4	GO:0005025	transforming growth factor beta receptor activity, type I(GO:0005025)
0.1	1.0	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.3	GO:0005347	ATP transmembrane transporter activity(GO:0005347)
0.1	0.4	GO:0004035	alkaline phosphatase activity(GO:0004035)
0.1	0.9	GO:0030898	actin-dependent ATPase activity(GO:0030898)
0.1	0.2	GO:0016743	carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1	0.3	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.1	0.4	GO:0004758	serine C-palmitoyltransferase activity(GO:0004758)
0.1	0.3	GO:0016899	oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899)
0.1	1.0	GO:0034236	protein kinase A catalytic subunit binding(GO:0034236)
0.1	0.3	GO:0071614	linoleic acid epoxygenase activity(GO:0071614)
0.1	0.5	GO:0070097	delta-catenin binding(GO:0070097)
0.1	0.2	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.1	0.2	GO:0017098	sulfonylurea receptor binding(GO:0017098)
0.1	0.2	GO:0033300	dehydroascorbic acid transporter activity(GO:0033300)
0.0	0.1	GO:0004366	glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0	0.2	GO:0004176	ATP-dependent peptidase activity(GO:0004176)
0.0	1.6	GO:0005158	insulin receptor binding(GO:0005158)
0.0	1.2	GO:0046875	ephrin receptor binding(GO:0046875)
0.0	0.3	GO:0043184	vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.0	0.5	GO:0045295	gamma-catenin binding(GO:0045295)
0.0	0.2	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.2	GO:0008131	primary amine oxidase activity(GO:0008131)
0.0	0.4	GO:0070182	DNA polymerase binding(GO:0070182)
0.0	0.1	GO:0004069	L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.0	0.8	GO:0030332	cyclin binding(GO:0030332)
0.0	0.2	GO:0005095	GTPase inhibitor activity(GO:0005095)
0.0	0.3	GO:0005337	nucleoside transmembrane transporter activity(GO:0005337)
0.0	0.1	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0	0.3	GO:0004143	diacylglycerol kinase activity(GO:0004143)
0.0	0.1	GO:0003708	retinoic acid receptor activity(GO:0003708)
0.0	0.1	GO:0050692	DBD domain binding(GO:0050692)
0.0	0.1	GO:0071208	histone pre-mRNA DCP binding(GO:0071208)
0.0	0.1	GO:0030942	endoplasmic reticulum signal peptide binding(GO:0030942)
0.0	0.1	GO:0030297	transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0	0.1	GO:0016802	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.1	GO:0035663	Toll-like receptor 2 binding(GO:0035663)
0.0	0.4	GO:0042800	histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0	0.1	GO:0005047	signal recognition particle binding(GO:0005047)
0.0	1.5	GO:0019209	kinase activator activity(GO:0019209)
0.0	0.1	GO:0016509	long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.0	0.1	GO:0008142	oxysterol binding(GO:0008142)
0.0	0.5	GO:0017134	fibroblast growth factor binding(GO:0017134)
0.0	0.1	GO:0071074	eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.6	GO:0001205	transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0	0.1	GO:0016286	small conductance calcium-activated potassium channel activity(GO:0016286)
0.0	0.1	GO:2001070	starch binding(GO:2001070)
0.0	0.1	GO:0004887	thyroid hormone receptor activity(GO:0004887)
0.0	0.6	GO:0004364	glutathione transferase activity(GO:0004364)
0.0	0.1	GO:0001727	lipid kinase activity(GO:0001727)
0.0	0.1	GO:0034235	GPI anchor binding(GO:0034235)
0.0	0.9	GO:0005546	phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0	0.1	GO:0016401	palmitoyl-CoA oxidase activity(GO:0016401)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0050733	RS domain binding(GO:0050733)
0.0	0.1	GO:0047499	calcium-independent phospholipase A2 activity(GO:0047499)
0.0	0.3	GO:0003756	protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0	0.0	GO:0005157	macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0	0.1	GO:0042015	interleukin-20 binding(GO:0042015)
0.0	0.3	GO:0005086	ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0	0.3	GO:0043395	heparan sulfate proteoglycan binding(GO:0043395)
0.0	0.3	GO:0004117	calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.0	0.0	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.0	0.2	GO:0015035	protein disulfide oxidoreductase activity(GO:0015035)
0.0	0.0	GO:0045503	dynein light chain binding(GO:0045503)
0.0	0.1	GO:0008508	bile acid:sodium symporter activity(GO:0008508)
0.0	0.1	GO:0019203	carbohydrate phosphatase activity(GO:0019203) sugar-phosphatase activity(GO:0050308)
0.0	0.1	GO:0004128	cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0	0.1	GO:0008494	translation activator activity(GO:0008494)
0.0	0.1	GO:0032552	deoxyribonucleotide binding(GO:0032552)
0.0	0.2	GO:0008266	poly(U) RNA binding(GO:0008266)
0.0	1.1	GO:0004222	metalloendopeptidase activity(GO:0004222)
0.0	0.0	GO:0030943	mitochondrion targeting sequence binding(GO:0030943)
0.0	0.0	GO:0047555	3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0	0.5	GO:0005518	collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.8	PID ERBB NETWORK PATHWAY	ErbB receptor signaling network
0.0	0.7	PID INTEGRIN5 PATHWAY	Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0	1.1	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	1.0	PID RET PATHWAY	Signaling events regulated by Ret tyrosine kinase
0.0	0.3	PID VEGF VEGFR PATHWAY	VEGF and VEGFR signaling network
0.0	0.9	PID RETINOIC ACID PATHWAY	Retinoic acid receptors-mediated signaling
0.0	0.5	PID ARF 3PATHWAY	Arf1 pathway
0.0	0.6	PID ERBB1 INTERNALIZATION PATHWAY	Internalization of ErbB1
0.0	0.9	SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES	Genes related to the insulin receptor pathway
0.0	0.1	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.3	PID CIRCADIAN PATHWAY	Circadian rhythm pathway
0.0	0.1	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	0.4	PID LIS1 PATHWAY	Lissencephaly gene (LIS1) in neuronal migration and development
0.0	0.2	PID FAS PATHWAY	FAS (CD95) signaling pathway
0.0	0.1	ST INTERFERON GAMMA PATHWAY	Interferon gamma pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	1.6	REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE	Genes involved in Synthesis of PIPs at the late endosome membrane
0.1	0.9	REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE	Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0	0.8	REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR	Genes involved in Signaling by constitutively active EGFR
0.0	0.6	REACTOME COMMON PATHWAY	Genes involved in Common Pathway
0.0	0.9	REACTOME SMOOTH MUSCLE CONTRACTION	Genes involved in Smooth Muscle Contraction
0.0	0.3	REACTOME VEGF LIGAND RECEPTOR INTERACTIONS	Genes involved in VEGF ligand-receptor interactions
0.0	0.6	REACTOME GLUTATHIONE CONJUGATION	Genes involved in Glutathione conjugation
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME PYRIMIDINE CATABOLISM	Genes involved in Pyrimidine catabolism
0.0	0.4	REACTOME HS GAG DEGRADATION	Genes involved in HS-GAG degradation
0.0	0.2	REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION	Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0	0.5	REACTOME GLUCONEOGENESIS	Genes involved in Gluconeogenesis
0.0	0.3	REACTOME LYSOSOME VESICLE BIOGENESIS	Genes involved in Lysosome Vesicle Biogenesis
0.0	0.2	REACTOME N GLYCAN ANTENNAE ELONGATION	Genes involved in N-Glycan antennae elongation
0.0	0.2	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME EFFECTS OF PIP2 HYDROLYSIS	Genes involved in Effects of PIP2 hydrolysis
0.0	0.1	REACTOME RETROGRADE NEUROTROPHIN SIGNALLING	Genes involved in Retrograde neurotrophin signalling
0.0	0.3	REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION	Genes involved in Nuclear Events (kinase and transcription factor activation)
0.0	0.3	REACTOME MYOGENESIS	Genes involved in Myogenesis
0.0	0.2	REACTOME RNA POL III TRANSCRIPTION TERMINATION	Genes involved in RNA Polymerase III Transcription Termination
0.0	0.8	REACTOME SIGNALING BY EGFR IN CANCER	Genes involved in Signaling by EGFR in Cancer
0.0	0.1	REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION	Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0	0.1	REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS	Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis