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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Zkscan3

Z-value: 3.04

Motif logo

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Transcription factors associated with Zkscan3

Gene Symbol Gene ID Gene Info
Zkscan3
ENSMUSG00000021327.12 zinc finger with KRAB and SCAN domains 3

Correlations of motif activity and signal intensity at CREs associated with the motif's TFs:

This plot shows correlation between observed signal intensity of a CRE associated with the transcription factor across all samples and activity of the motif.

For each TF, only the top 5 correlated CREs are shown.

CRE Gene Distance Association probability Pearson corr. coef. P-value Plot
chr13_21402344_21402506Zkscan32450.8077950.758.8e-02Click!
chr13_21402673_21402832Zkscan330.9382890.602.1e-01Click!
chr13_21401689_21401902Zkscan38750.3368240.582.2e-01Click!
chr13_21402012_21402170Zkscan35790.5068730.522.9e-01Click!
chr13_21401499_21401673Zkscan310840.264744-0.355.0e-01Click!

Activity of the Zkscan3 motif across conditions

Conditions sorted by the z-value of the Zkscan3 motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr9_65334133_65334359 4.38 Gm39363
 predicted gene, 39363
 1726
 0.18
chr8_35387028_35387898 2.40 Ppp1r3b
 protein phosphatase 1, regulatory subunit 3B
 10803
 0.16
chr13_93628549_93628834 2.21 Gm15622
 predicted gene 15622
 3309
 0.2
chr16_97900645_97900797 1.94 C2cd2
 C2 calcium-dependent domain containing 2
 8440
 0.18
chr5_112299397_112299785 1.79 Tpst2
 protein-tyrosine sulfotransferase 2
 4305
 0.13
chr7_98352590_98353259 1.71 Tsku
 tsukushi, small leucine rich proteoglycan
 7155
 0.18
chr6_122819078_122819314 1.52 Foxj2
 forkhead box J2
 718
 0.44
chr9_61826654_61826867 1.52 Gm19208
 predicted gene, 19208
 24944
 0.2
chr11_4906060_4906238 1.50 Thoc5
 THO complex 5
 3937
 0.15
chr3_98226583_98226734 1.40 Reg4
 regenerating islet-derived family, member 4
 4502
 0.17
chr6_144781221_144781581 1.40 Sox5
 SRY (sex determining region Y)-box 5
 518
 0.79
chr14_21171384_21171535 1.30 Adk
 adenosine kinase
 95307
 0.07
chr19_3650199_3650464 1.28 Lrp5
 low density lipoprotein receptor-related protein 5
 34539
 0.1
chr14_76556939_76557219 1.27 Serp2
 stress-associated endoplasmic reticulum protein family member 2
 190
 0.95
chr17_28436590_28436749 1.26 Fkbp5
 FK506 binding protein 5
 4341
 0.12
chr19_61048296_61048486 1.24 Gm22520
 predicted gene, 22520
 34846
 0.14
chr7_125578941_125579144 1.21 Gm44876
 predicted gene 44876
 6925
 0.16
chr8_120369815_120369966 1.21 Gm22715
 predicted gene, 22715
 73659
 0.09
chr17_33932399_33932565 1.20 Rgl2
 ral guanine nucleotide dissociation stimulator-like 2
 351
 0.58
chr8_41026178_41026329 1.17 Mtus1
 mitochondrial tumor suppressor 1
 3351
 0.19
chr7_98849207_98849358 1.14 Wnt11
 wingless-type MMTV integration site family, member 11
 1476
 0.34
chr10_95317812_95318192 1.13 Gm48882
 predicted gene, 48882
 245
 0.88
chr2_153586432_153586583 1.13 Commd7
 COMM domain containing 7
 46224
 0.11
chr1_74061177_74061331 1.13 Tns1
 tensin 1
 24097
 0.17
chr6_145764862_145765013 1.09 Rassf8
 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
 14366
 0.19
chr14_100324093_100324244 1.07 Gm41231
 predicted gene, 41231
 38003
 0.15
chr15_36472644_36473037 1.06 Ankrd46
 ankyrin repeat domain 46
 23875
 0.13
chr10_80340392_80340718 1.02 Adamtsl5
 ADAMTS-like 5
 470
 0.56
chr8_124201642_124201985 1.00 Galnt2
 polypeptide N-acetylgalactosaminyltransferase 2
 29578
 0.15
chr4_140858134_140858561 1.00 Padi1
 peptidyl arginine deiminase, type I
 12569
 0.12
chr10_122986042_122986255 1.00 D630033A02Rik
 RIKEN cDNA D630033A02 gene
 317
 0.58
chr18_73844340_73844698 0.99 Mro
 maestro
 14866
 0.2
chr17_46110701_46110892 0.99 Mrps18a
 mitochondrial ribosomal protein S18A
 190
 0.91
chr5_126543958_126544274 0.99 Gm24839
 predicted gene, 24839
 30135
 0.19
chr9_115476457_115476622 0.99 Gm5921
 predicted gene 5921
 37958
 0.14
chr6_42352219_42352377 0.98 Zyx
 zyxin
 1180
 0.24
chr18_70568874_70569217 0.98 Mbd2
 methyl-CpG binding domain protein 2
 711
 0.68
chr2_167326193_167326424 0.98 B4galt5
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
 12408
 0.18
chr2_126570201_126570813 0.98 Slc27a2
 solute carrier family 27 (fatty acid transporter), member 2
 5747
 0.2
chr17_30619245_30619423 0.97 Dnah8
 dynein, axonemal, heavy chain 8
 5020
 0.12
chr7_127214965_127215278 0.97 Septin1
 septin 1
 4
 0.92
chr5_24586259_24586557 0.97 Chpf2
 chondroitin polymerizing factor 2
 333
 0.76
chr9_118925675_118926262 0.97 Gm2415
 predicted gene 2415
 290
 0.62
chr13_19395072_19395660 0.96 Gm42683
 predicted gene 42683
 87
 0.82
chr9_32004053_32004204 0.96 Gm47465
 predicted gene, 47465
 1332
 0.4
chr8_124897995_124898160 0.96 Sprtn
 SprT-like N-terminal domain
 191
 0.68
chr4_149978768_149979375 0.95 H6pd
 hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
 22194
 0.13
chr13_28421437_28421636 0.94 Gm40841
 predicted gene, 40841
 1470
 0.49
chr16_33947299_33947485 0.94 Itgb5
 integrin beta 5
 868
 0.56
chr4_133049992_133050178 0.92 Ahdc1
 AT hook, DNA binding motif, containing 1
 10592
 0.19
chr15_79141450_79141641 0.92 Polr2f
 polymerase (RNA) II (DNA directed) polypeptide F
 179
 0.62
chr4_118132718_118132924 0.91 St3gal3
 ST3 beta-galactoside alpha-2,3-sialyltransferase 3
 2061
 0.28
chr3_103789902_103790723 0.90 Hipk1
 homeodomain interacting protein kinase 1
 763
 0.4
chr3_101519636_101519818 0.90 Atp1a1
 ATPase, Na+/K+ transporting, alpha 1 polypeptide
 57833
 0.1
chr9_70940473_70940653 0.88 Lipc
 lipase, hepatic
 5755
 0.22
chr13_113864739_113864979 0.88 Arl15
 ADP-ribosylation factor-like 15
 70237
 0.09
chr8_12677440_12677591 0.88 4931415C17Rik
 RIKEN cDNA 4931415C17 gene
 5088
 0.15
chr13_60644455_60644612 0.87 Gm48583
 predicted gene, 48583
 2743
 0.25
chr15_34469803_34469957 0.86 Gm49188
 predicted gene, 49188
 11827
 0.1
chr12_100199636_100199926 0.86 Calm1
 calmodulin 1
 252
 0.89
chr2_75603496_75603684 0.84 Gm13655
 predicted gene 13655
 29792
 0.14
chr11_116104363_116104575 0.82 Trim47
 tripartite motif-containing 47
 2614
 0.14
chr2_30268240_30268600 0.82 Phyhd1
 phytanoyl-CoA dioxygenase domain containing 1
 1557
 0.21
chr10_81419362_81419546 0.81 Mir1191b
 microRNA 1191b
 3157
 0.08
chr19_7240751_7240928 0.80 Naa40
 N(alpha)-acetyltransferase 40, NatD catalytic subunit
 195
 0.89
chr5_124353375_124353533 0.80 Cdk2ap1
 CDK2 (cyclin-dependent kinase 2)-associated protein 1
 1217
 0.33
chr5_89462978_89463338 0.79 Gc
 vitamin D binding protein
 5260
 0.24
chr2_32682708_32682915 0.78 Fpgs
 folylpolyglutamyl synthetase
 2193
 0.12
chr8_11262573_11262724 0.77 Col4a1
 collagen, type IV, alpha 1
 17008
 0.16
chr19_5851015_5851290 0.77 Frmd8os
 FERM domain containing 8, opposite strand
 2644
 0.11
chr16_17235100_17235306 0.77 Hic2
 hypermethylated in cancer 2
 1539
 0.2
chr9_96727975_96728455 0.76 Zbtb38
 zinc finger and BTB domain containing 38
 821
 0.58
chr18_20670501_20671004 0.76 Ttr
 transthyretin
 5472
 0.18
chr3_137863947_137864380 0.76 Gm43403
 predicted gene 43403
 20
 0.81
chr19_44400900_44401269 0.76 Scd1
 stearoyl-Coenzyme A desaturase 1
 5606
 0.16
chr7_16597600_16597898 0.75 Gm29443
 predicted gene 29443
 16075
 0.09
chr9_90109465_90109757 0.74 Morf4l1
 mortality factor 4 like 1
 4678
 0.17
chr16_38433421_38433613 0.74 Pla1a
 phospholipase A1 member A
 372
 0.8
chr11_60786856_60787068 0.73 Shmt1
 serine hydroxymethyltransferase 1 (soluble)
 6211
 0.09
chr19_46908820_46909200 0.73 Nt5c2
 5'-nucleotidase, cytosolic II
 565
 0.74
chr13_54076591_54076742 0.71 Sfxn1
 sideroflexin 1
 4797
 0.21
chr2_30436208_30436447 0.70 Ptpa
 protein phosphatase 2 protein activator
 1902
 0.22
chr3_146403874_146404213 0.70 Ssx2ip
 synovial sarcoma, X 2 interacting protein
 599
 0.64
chr7_98177945_98178149 0.69 Capn5
 calpain 5
 227
 0.83
chr11_75422344_75422535 0.69 Serpinf1
 serine (or cysteine) peptidase inhibitor, clade F, member 1
 113
 0.88
chr2_25708935_25709097 0.68 A230005M16Rik
 RIKEN cDNA A230005M16 gene
 700
 0.42
chr17_47873312_47873495 0.68 Foxp4
 forkhead box P4
 5550
 0.14
chr6_42251736_42251903 0.68 Gstk1
 glutathione S-transferase kappa 1
 5796
 0.11
chr2_173156797_173157495 0.68 Pck1
 phosphoenolpyruvate carboxykinase 1, cytosolic
 4064
 0.2
chr9_48738331_48738489 0.67 Zbtb16
 zinc finger and BTB domain containing 16
 97535
 0.07
chr4_62779675_62780043 0.67 Gm24117
 predicted gene, 24117
 32569
 0.15
chr2_32421538_32422351 0.67 Slc25a25
 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
 36
 0.95
chr16_84805927_84806078 0.66 Jam2
 junction adhesion molecule 2
 3405
 0.17
chr14_66129671_66129842 0.66 Ephx2
 epoxide hydrolase 2, cytoplasmic
 5256
 0.17
chr4_95625117_95625268 0.65 Fggy
 FGGY carbohydrate kinase domain containing
 1636
 0.46
chr9_122049922_122050484 0.65 Gm39465
 predicted gene, 39465
 1155
 0.34
chr9_20740746_20740928 0.65 Olfm2
 olfactomedin 2
 5512
 0.16
chr2_118844371_118844522 0.65 Gm14091
 predicted gene 14091
 10324
 0.12
chr6_113644583_113645202 0.65 Gm43964
 predicted gene, 43964
 3371
 0.09
chr11_102267338_102267489 0.65 Asb16
 ankyrin repeat and SOCS box-containing 16
 1330
 0.26
chr2_94067079_94067259 0.64 Hsd17b12
 hydroxysteroid (17-beta) dehydrogenase 12
 405
 0.86
chr19_20450928_20451527 0.64 C730002L08Rik
 RIKEN cDNA C730002L08 gene
 26445
 0.16
chr10_81233301_81233523 0.64 Zfr2
 zinc finger RNA binding protein 2
 225
 0.8
chr4_116006006_116006178 0.64 Faah
 fatty acid amide hydrolase
 6024
 0.15
chr11_75211079_75211230 0.63 Rtn4rl1
 reticulon 4 receptor-like 1
 17371
 0.1
chr10_24831746_24832070 0.63 Enpp3
 ectonucleotide pyrophosphatase/phosphodiesterase 3
 102
 0.97
chr11_107025954_107026367 0.63 1810010H24Rik
 RIKEN cDNA 1810010H24 gene
 479
 0.74
chr2_167328678_167328847 0.62 B4galt5
 UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
 14862
 0.18
chr15_99032417_99032770 0.62 Tuba1c
 tubulin, alpha 1C
 2272
 0.15
chr15_76745135_76745286 0.62 Arhgap39
 Rho GTPase activating protein 39
 19607
 0.08
chr15_31264328_31264561 0.62 Dap
 death-associated protein
 3892
 0.19
chr16_93823192_93823406 0.61 Morc3
 microrchidia 3
 8822
 0.13
chr10_33950641_33951001 0.60 Zup1
 zinc finger containing ubiquitin peptidase 1
 374
 0.76
chr9_53301822_53302322 0.60 Exph5
 exophilin 5
 402
 0.86
chr9_70234355_70234506 0.60 Myo1e
 myosin IE
 27062
 0.19
chr19_61048615_61048813 0.59 Gm22520
 predicted gene, 22520
 35169
 0.14
chr17_45834393_45834544 0.59 Gm35692
 predicted gene, 35692
 12145
 0.16
chr18_75601004_75601199 0.59 Ctif
 CBP80/20-dependent translation initiation factor
 36172
 0.19
chr19_43510545_43510713 0.58 Got1
 glutamic-oxaloacetic transaminase 1, soluble
 5236
 0.13
chrX_75874057_75874225 0.58 Pls3
 plastin 3 (T-isoform)
 433
 0.81
chr6_21828351_21828787 0.58 Tspan12
 tetraspanin 12
 23259
 0.17
chr14_70198497_70198662 0.57 Sorbs3
 sorbin and SH3 domain containing 3
 6044
 0.12
chr16_37635141_37635534 0.57 Hgd
 homogentisate 1, 2-dioxygenase
 13488
 0.15
chr5_66148784_66148935 0.57 Rbm47
 RNA binding motif protein 47
 2097
 0.18
chr1_88286437_88286600 0.57 Trpm8
 transient receptor potential cation channel, subfamily M, member 8
 8857
 0.11
chr8_124567905_124568437 0.56 Agt
 angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
 1535
 0.36
chr5_52975314_52975474 0.56 Gm30301
 predicted gene, 30301
 6643
 0.16
chr15_65846454_65846635 0.56 Efr3a
 EFR3 homolog A
 4577
 0.22
chr14_45220729_45220892 0.55 Txndc16
 thioredoxin domain containing 16
 482
 0.52
chr10_70097931_70098284 0.55 Ccdc6
 coiled-coil domain containing 6
 986
 0.66
chr8_120366684_120367118 0.55 Gm22715
 predicted gene, 22715
 76648
 0.08
chr9_62342926_62343110 0.55 Anp32a
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 554
 0.78
chr2_31479577_31479870 0.54 Ass1
 argininosuccinate synthetase 1
 9516
 0.19
chr9_62367194_62367386 0.54 Anp32a
 acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
 346
 0.89
chr4_132628872_132629046 0.53 Eya3
 EYA transcriptional coactivator and phosphatase 3
 10028
 0.15
chr15_79733610_79733958 0.53 Sun2
 Sad1 and UNC84 domain containing 2
 2167
 0.15
chr16_13201906_13202058 0.53 Mrtfb
 myocardin related transcription factor B
 54499
 0.14
chr16_72830483_72830654 0.53 Robo1
 roundabout guidance receptor 1
 145781
 0.05
chr7_79831481_79831780 0.52 Gm44974
 predicted gene 44974
 241
 0.87
chr16_85901352_85901509 0.52 Adamts5
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
 398
 0.9
chr2_163301297_163301733 0.52 Tox2
 TOX high mobility group box family member 2
 18863
 0.19
chr10_61143381_61143586 0.52 Sgpl1
 sphingosine phosphate lyase 1
 3415
 0.19
chr16_45975826_45976145 0.52 Phldb2
 pleckstrin homology like domain, family B, member 2
 22387
 0.14
chr5_73337973_73338415 0.52 Ociad2
 OCIA domain containing 2
 364
 0.79
chr19_6855220_6855477 0.52 Ccdc88b
 coiled-coil domain containing 88B
 110
 0.93
chr1_86879397_86879607 0.51 Gm37541
 predicted gene, 37541
 5152
 0.12
chr16_91833643_91834213 0.50 Itsn1
 intersectin 1 (SH3 domain protein 1A)
 5771
 0.19
chr6_91655124_91655309 0.50 Gm45217
 predicted gene 45217
 24007
 0.11
chr8_33871610_33871761 0.50 Gm26978
 predicted gene, 26978
 14062
 0.16
chr1_158142001_158142160 0.50 Brinp2
 bone morphogenic protein/retinoic acid inducible neural-specific 2
 154384
 0.04
chr9_106756626_106756783 0.50 Rad54l2
 RAD54 like 2 (S. cerevisiae)
 32472
 0.12
chr8_119912901_119913087 0.49 Usp10
 ubiquitin specific peptidase 10
 2137
 0.24
chr7_79781946_79782169 0.49 Gm44705
 predicted gene 44705
 8568
 0.1
chr10_81422057_81422238 0.49 Nfic
 nuclear factor I/C
 4967
 0.07
chr13_99099705_99099869 0.49 Gm807
 predicted gene 807
 919
 0.55
chr4_43421375_43421673 0.49 Rusc2
 RUN and SH3 domain containing 2
 968
 0.4
chr9_44387040_44387229 0.49 Hyou1
 hypoxia up-regulated 1
 3527
 0.07
chr4_8754704_8754856 0.49 Chd7
 chromodomain helicase DNA binding protein 7
 3342
 0.36
chr2_180906861_180907031 0.48 Gm27032
 predicted gene, 27032
 12841
 0.09
chr17_71255942_71256093 0.48 Emilin2
 elastin microfibril interfacer 2
 329
 0.86
chr13_37874544_37874704 0.48 Rreb1
 ras responsive element binding protein 1
 13810
 0.2
chr19_6924075_6924226 0.48 Catsperz
 cation channel sperm associated auxiliary subunit zeta
 719
 0.37
chr8_83589428_83589579 0.48 Gm45823
 predicted gene 45823
 3978
 0.11
chrX_140525251_140525408 0.48 Tsc22d3
 TSC22 domain family, member 3
 17339
 0.19
chr8_35207158_35207309 0.47 Gm34474
 predicted gene, 34474
 11405
 0.14
chr10_111364892_111365156 0.47 Gm40761
 predicted gene, 40761
 27900
 0.17
chr9_14439768_14439948 0.47 Gm47318
 predicted gene, 47318
 4447
 0.13
chr10_75794436_75794892 0.47 Gstt1
 glutathione S-transferase, theta 1
 2905
 0.13
chr8_81378490_81378647 0.46 Inpp4b
 inositol polyphosphate-4-phosphatase, type II
 36006
 0.19
chr8_80856636_80856789 0.46 Gm31105
 predicted gene, 31105
 23228
 0.16
chr10_69102086_69102245 0.46 Gm47107
 predicted gene, 47107
 4299
 0.21
chr3_52605604_52605772 0.46 Gm10293
 predicted pseudogene 10293
 7147
 0.26
chr7_116443673_116444404 0.45 AV356131
 expressed sequence AV356131
 463
 0.52
chr7_30895336_30895491 0.45 D7Ertd128e
 DNA segment, Chr 7, ERATO Doi 128, expressed
 10382
 0.07
chr19_58021843_58021994 0.45 Mir5623
 microRNA 5623
 29249
 0.23
chr19_5831533_5832364 0.45 Neat1
 nuclear paraspeckle assembly transcript 1 (non-protein coding)
 3936
 0.09
chr7_123407139_123407415 0.45 Lcmt1
 leucine carboxyl methyltransferase 1
 903
 0.58
chr8_24457283_24457668 0.44 Gm44620
 predicted gene 44620
 10378
 0.15
chr7_3331834_3332020 0.44 Cacng7
 calcium channel, voltage-dependent, gamma subunit 7
 1028
 0.31
chr9_98986714_98987086 0.44 Faim
 Fas apoptotic inhibitory molecule
 493
 0.73
chr15_83452182_83452447 0.44 Pacsin2
 protein kinase C and casein kinase substrate in neurons 2
 12238
 0.15
chr1_60609032_60609279 0.44 Gm23762
 predicted gene, 23762
 4648
 0.15
chr9_21725120_21725502 0.43 Ldlr
 low density lipoprotein receptor
 1670
 0.23
chr6_28737275_28737426 0.43 Snd1
 staphylococcal nuclease and tudor domain containing 1
 27340
 0.19
chr9_102737824_102737975 0.42 Gm5627
 predicted gene 5627
 1749
 0.25
chr18_80254812_80254963 0.42 Slc66a2
 solute carrier family 66 member 2
 358
 0.79
chr10_68259248_68259399 0.41 Arid5b
 AT rich interactive domain 5B (MRF1-like)
 19398
 0.21
chr4_152027330_152027509 0.41 Zbtb48
 zinc finger and BTB domain containing 48
 218
 0.87
chr7_114769396_114769572 0.41 Insc
 INSC spindle orientation adaptor protein
 710
 0.68
chr13_43499439_43499647 0.41 Gm47683
 predicted gene, 47683
 624
 0.64
chr7_119941261_119941568 0.41 Lyrm1
 LYR motif containing 1
 4456
 0.17
chr17_12921475_12921639 0.40 Snora20
 small nucleolar RNA, H/ACA box 20
 1233
 0.19
chr7_19457920_19458071 0.40 Mark4
 MAP/microtubule affinity regulating kinase 4
 800
 0.36
chr2_158070723_158070992 0.40 2010009K17Rik
 RIKEN cDNA 2010009K17 gene
 20940
 0.14
chr9_80067924_80068106 0.40 Senp6
 SUMO/sentrin specific peptidase 6
 198
 0.93
chr18_54984622_54984821 0.39 Zfp608
 zinc finger protein 608
 5445
 0.22
chr2_27696621_27697049 0.39 Rxra
 retinoid X receptor alpha
 12457
 0.25
chr19_46627552_46627707 0.39 Wbp1l
 WW domain binding protein 1 like
 4228
 0.16
chr11_100921491_100921782 0.38 Stat3
 signal transducer and activator of transcription 3
 13412
 0.14
chr9_69290695_69290919 0.38 Rora
 RAR-related orphan receptor alpha
 1125
 0.59

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Zkscan3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.0 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.2 0.7 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.1 0.4 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.1 0.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.3 GO:0000087 mitotic M phase(GO:0000087)
0.1 0.3 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.3 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.5 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:0010046 response to mycotoxin(GO:0010046)
0.1 0.5 GO:0043102 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.1 0.4 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.2 GO:0046499 S-adenosylmethioninamine metabolic process(GO:0046499)
0.1 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.3 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.1 0.1 GO:1900019 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.1 0.3 GO:0001927 exocyst assembly(GO:0001927)
0.1 0.3 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.4 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.2 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.6 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.2 GO:0043435 response to corticotropin-releasing hormone(GO:0043435) cellular response to corticotropin-releasing hormone stimulus(GO:0071376)
0.1 0.2 GO:0021553 olfactory nerve development(GO:0021553)
0.1 0.3 GO:0018101 protein citrullination(GO:0018101)
0.1 0.2 GO:2001274 negative regulation of glucose import in response to insulin stimulus(GO:2001274)
0.1 0.2 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.2 GO:1904016 response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.2 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.5 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.2 GO:0009256 10-formyltetrahydrofolate metabolic process(GO:0009256)
0.0 0.2 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.4 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.1 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.5 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.6 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.1 GO:0045626 negative regulation of T-helper 1 cell differentiation(GO:0045626)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0001692 histamine metabolic process(GO:0001692)
0.0 0.3 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.0 0.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 0.1 GO:0045715 negative regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045715)
0.0 0.2 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0072310 glomerular visceral epithelial cell development(GO:0072015) glomerular epithelial cell development(GO:0072310)
0.0 0.1 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.0 0.1 GO:0060319 primitive erythrocyte differentiation(GO:0060319)
0.0 0.2 GO:1903689 regulation of wound healing, spreading of epidermal cells(GO:1903689)
0.0 0.3 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1903935 neurofilament bundle assembly(GO:0033693) peripheral nervous system neuron axonogenesis(GO:0048936) response to sodium arsenite(GO:1903935)
0.0 0.1 GO:0009130 pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130) deoxyribonucleoside monophosphate biosynthetic process(GO:0009157) pyrimidine deoxyribonucleoside monophosphate biosynthetic process(GO:0009177)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.2 GO:0071830 chylomicron remnant clearance(GO:0034382) triglyceride-rich lipoprotein particle clearance(GO:0071830)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.2 GO:0034625 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of exocyst localization(GO:0060178)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.1 GO:0006768 biotin metabolic process(GO:0006768)
0.0 0.2 GO:0021894 cerebral cortex GABAergic interneuron development(GO:0021894)
0.0 0.1 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0071335 hair follicle cell proliferation(GO:0071335)
0.0 0.1 GO:1903416 response to glycoside(GO:1903416)
0.0 0.1 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.0 0.1 GO:0070836 caveola assembly(GO:0070836)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.0 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.2 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.1 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0003273 cell migration involved in endocardial cushion formation(GO:0003273)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.0 0.1 GO:0060921 sinoatrial node cell differentiation(GO:0060921)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.3 GO:0000132 establishment of mitotic spindle orientation(GO:0000132)
0.0 0.3 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.1 GO:0019254 carnitine metabolic process, CoA-linked(GO:0019254)
0.0 0.1 GO:1900242 regulation of synaptic vesicle endocytosis(GO:1900242)
0.0 0.5 GO:0002021 response to dietary excess(GO:0002021)
0.0 0.0 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0071873 response to norepinephrine(GO:0071873)
0.0 0.5 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.0 GO:0046103 inosine biosynthetic process(GO:0046103)
0.0 0.1 GO:0002432 granuloma formation(GO:0002432)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0050955 thermoception(GO:0050955)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.1 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.1 GO:0043313 regulation of neutrophil degranulation(GO:0043313)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0090051 negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.2 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.1 GO:0061623 galactose catabolic process via UDP-galactose(GO:0033499) glycolytic process from galactose(GO:0061623)
0.0 0.8 GO:0043388 positive regulation of DNA binding(GO:0043388)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 0.1 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.2 GO:0001973 adenosine receptor signaling pathway(GO:0001973)
0.0 0.0 GO:0051795 positive regulation of catagen(GO:0051795)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.2 GO:0042559 pteridine-containing compound biosynthetic process(GO:0042559)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.2 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.2 GO:0032988 ribonucleoprotein complex disassembly(GO:0032988)
0.0 0.1 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.1 GO:0030497 fatty acid elongation(GO:0030497)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.5 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0070126 mitochondrial translational termination(GO:0070126)
0.0 0.1 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.0 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.1 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.1 GO:0086013 membrane repolarization during cardiac muscle cell action potential(GO:0086013)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.2 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.1 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.0 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.1 GO:0006551 leucine metabolic process(GO:0006551)
0.0 0.0 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.0 GO:0018197 peptidyl-aspartic acid modification(GO:0018197)
0.0 0.5 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0042518 negative regulation of tyrosine phosphorylation of Stat3 protein(GO:0042518)
0.0 0.0 GO:0046271 phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0008078 mesodermal cell migration(GO:0008078)
0.0 0.0 GO:0045297 mating plug formation(GO:0042628) post-mating behavior(GO:0045297)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.0 GO:0003072 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)
0.0 0.0 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.0 0.3 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.1 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.4 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.1 GO:0060391 positive regulation of SMAD protein import into nucleus(GO:0060391)
0.0 0.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.1 GO:0060050 positive regulation of protein glycosylation(GO:0060050)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.0 GO:0021843 substrate-independent telencephalic tangential migration(GO:0021826) interneuron migration from the subpallium to the cortex(GO:0021830) substrate-independent telencephalic tangential interneuron migration(GO:0021843)
0.0 0.1 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.1 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.0 GO:0061724 lipophagy(GO:0061724)
0.0 0.0 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.0 0.1 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.0 GO:0071316 cellular response to nicotine(GO:0071316)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.1 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.1 GO:0019482 beta-alanine metabolic process(GO:0019482)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.0 0.0 GO:0021827 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.0 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.0 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:2000643 positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.1 GO:1901978 positive regulation of cell cycle checkpoint(GO:1901978)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.2 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.0 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.0 0.0 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.0 0.0 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.1 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 0.0 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.0 GO:0031627 telomeric loop formation(GO:0031627)
0.0 0.0 GO:1902416 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.0 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.0 0.2 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.0 GO:0009448 gamma-aminobutyric acid metabolic process(GO:0009448)
0.0 0.1 GO:0070189 kynurenine metabolic process(GO:0070189)
0.0 0.0 GO:1901341 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.0 GO:1902023 L-arginine import(GO:0043091) arginine import(GO:0090467) L-arginine transport(GO:1902023)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0043203 axon hillock(GO:0043203)
0.1 0.2 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 0.6 GO:0001527 microfibril(GO:0001527)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.0 0.6 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0031429 box H/ACA snoRNP complex(GO:0031429) box H/ACA RNP complex(GO:0072588)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0005796 Golgi lumen(GO:0005796)
0.0 0.1 GO:0042827 platelet dense granule(GO:0042827)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.6 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0098827 endoplasmic reticulum subcompartment(GO:0098827)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.1 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.0 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.1 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.0 0.1 GO:0000938 GARP complex(GO:0000938)
0.0 0.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.2 GO:0001741 XY body(GO:0001741)
0.0 0.2 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.0 GO:0032444 activin responsive factor complex(GO:0032444)
0.0 1.0 GO:0034705 potassium channel complex(GO:0034705)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.5 GO:0032420 stereocilium(GO:0032420)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.2 GO:0016607 nuclear speck(GO:0016607)
0.0 0.1 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.1 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.2 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0045180 basal cortex(GO:0045180)
0.0 0.0 GO:0030891 VCB complex(GO:0030891)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.2 0.6 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.2 0.8 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 0.6 GO:0016509 long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0016509)
0.2 0.5 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.1 0.3 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.7 GO:0035197 siRNA binding(GO:0035197)
0.1 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0019797 procollagen-proline 3-dioxygenase activity(GO:0019797)
0.1 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886) DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates(GO:0051718)
0.1 0.3 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.3 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.1 0.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.1 0.3 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.2 GO:0004345 glucose-6-phosphate dehydrogenase activity(GO:0004345)
0.1 0.2 GO:0017153 sodium:dicarboxylate symporter activity(GO:0017153)
0.1 0.2 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471)
0.1 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0004611 phosphoenolpyruvate carboxykinase activity(GO:0004611)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.4 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.7 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.0 GO:1990715 mRNA CDS binding(GO:1990715)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.2 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.3 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.0 0.3 GO:0052811 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.3 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.0 0.1 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.0 GO:0030284 estrogen receptor activity(GO:0030284)
0.0 0.7 GO:0018711 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.2 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0019862 IgA binding(GO:0019862)
0.0 0.1 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.1 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.1 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.1 GO:0016406 carnitine O-acyltransferase activity(GO:0016406)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0048531 beta-1,3-galactosyltransferase activity(GO:0048531)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.4 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.1 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.0 0.0 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0008469 histone-arginine N-methyltransferase activity(GO:0008469) protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0004966 galanin receptor activity(GO:0004966)
0.0 0.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.0 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 1.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280)
0.0 0.0 GO:0015065 uridine nucleotide receptor activity(GO:0015065) G-protein coupled pyrimidinergic nucleotide receptor activity(GO:0071553)
0.0 0.1 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.0 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.0 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.0 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0016920 pyroglutamyl-peptidase activity(GO:0016920)
0.0 0.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 0.0 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.6 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.0 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.0 GO:0004505 phenylalanine 4-monooxygenase activity(GO:0004505)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.0 0.3 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.0 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 1.3 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.2 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.6 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.0 0.5 PID NFAT 3PATHWAY Role of Calcineurin-dependent NFAT signaling in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.1 0.7 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.1 0.8 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.1 1.1 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.7 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.7 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.0 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.5 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME NUCLEOTIDE BINDING DOMAIN LEUCINE RICH REPEAT CONTAINING RECEPTOR NLR SIGNALING PATHWAYS Genes involved in Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
0.0 0.0 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.1 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.1 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing