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ENCSR904DTN: DNase-seq of mouse liver in constant darkness

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CREMA is a free online tool that recognizes most important transcription factors that change the chromatin state across different samples.

Results for Zscan4c

Z-value: 1.77

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Transcription factors associated with Zscan4c

Gene Symbol	Gene ID	Gene Info
Zscan4c Ensembl NCBI MGI UniProt	ENSMUSG00000054272.5	Zscan4c

Activity of the Zscan4c motif across conditions

Conditions sorted by the z-value of the Zscan4c motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE)	Target Score	Top associated gene	Gene Info	Distance of CRE to TSS	CRE/Gene association probability
chr18_12732086_12732318	2.30	Ttc39c	tetratricopeptide repeat domain 39C	2503	0.2
chr18_12731812_12732024	1.23	Ttc39c	tetratricopeptide repeat domain 39C	2787	0.19
chr5_38117047_38117323	1.04	Stx18	syntaxin 18	3724	0.2
chr9_122119702_122119865	1.02	Gm47122	predicted gene, 47122	638	0.56
chr1_162966082_162966252	0.99	Gm37273	predicted gene, 37273	16847	0.15
chr11_117831026_117831177	0.92	Afmid	arylformamidase	1003	0.31
chr9_44387040_44387229	0.86	Hyou1	hypoxia up-regulated 1	3527	0.07
chr3_138233542_138233745	0.84	Adh7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide	5592	0.13
chr5_27996032_27996183	0.82	Gm4865	predicted gene 4865	5199	0.19
chr16_90199102_90199289	0.77	Gm49704	predicted gene, 49704	1047	0.47
chr17_64644726_64644989	0.75	Man2a1	mannosidase 2, alpha 1	44121	0.17
chr18_49980030_49980460	0.75	Tnfaip8	tumor necrosis factor, alpha-induced protein 8	710	0.72
chr1_182763696_182764002	0.73	Susd4	sushi domain containing 4	11	0.98
chr11_110177974_110178125	0.70	Abca9	ATP-binding cassette, sub-family A (ABC1), member 9	9853	0.25
chr5_96161523_96161844	0.68	Cnot6l	CCR4-NOT transcription complex, subunit 6-like	59	0.98
chr3_136670359_136670659	0.68	Ppp3ca	protein phosphatase 3, catalytic subunit, alpha isoform	261	0.94
chr4_106763916_106764094	0.68	Acot11	acyl-CoA thioesterase 11	7551	0.15
chr3_97645418_97646002	0.67	Prkab2	protein kinase, AMP-activated, beta 2 non-catalytic subunit	12483	0.13
chr9_30820894_30821215	0.67	Gm31013	predicted gene, 31013	39575	0.16
chr1_127730419_127730668	0.63	Acmsd	amino carboxymuconate semialdehyde decarboxylase	1130	0.5
chr7_126273472_126273659	0.63	Sbk1	SH3-binding kinase 1	165	0.92
chr8_117316911_117317193	0.58	Cmip	c-Maf inducing protein	32118	0.2
chr13_34635371_34635522	0.57	Pxdc1	PX domain containing 1	13122	0.13
chr11_81371218_81371402	0.56	4930527B05Rik	RIKEN cDNA 4930527B05 gene	13703	0.29
chr19_38399310_38399568	0.56	Slc35g1	solute carrier family 35, member G1	3398	0.2
chr9_44083899_44084207	0.56	Usp2	ubiquitin specific peptidase 2	886	0.32
chr13_60664706_60665228	0.55	Gm48583	predicted gene, 48583	23177	0.15
chrX_94541280_94541431	0.55	Maged1	melanoma antigen, family D, 1	635	0.62
chr6_137797018_137797169	0.54	Dera	deoxyribose-phosphate aldolase (putative)	259	0.94
chr3_31970158_31970309	0.53	Gm37834	predicted gene, 37834	15469	0.27
chr1_155808676_155809110	0.53	Qsox1	quiescin Q6 sulfhydryl oxidase 1	3927	0.15
chr17_57056615_57056782	0.53	Slc25a23	solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23	1313	0.19
chrX_85734642_85734808	0.51	Gk	glycerol kinase	2885	0.21
chr16_24517847_24518116	0.51	Morf4l1-ps1	mortality factor 4 like 1, pseudogene 1	11413	0.25
chr1_154117784_154118141	0.50	A830008E24Rik	RIKEN cDNA A830008E24 gene	11	0.98
chr6_136449342_136449720	0.50	Gm25882	predicted gene, 25882	31719	0.1
chr11_110496442_110496593	0.49	Map2k6	mitogen-activated protein kinase kinase 6	17478	0.25
chr10_80674829_80675669	0.48	Mknk2	MAP kinase-interacting serine/threonine kinase 2	1044	0.31
chr3_130999761_130999912	0.48	A430072C10Rik	RIKEN cDNA A430072C10 gene	26534	0.14
chr5_25015695_25015994	0.47	Prkag2	protein kinase, AMP-activated, gamma 2 non-catalytic subunit	20091	0.17
chr8_25776385_25776540	0.47	Bag4	BCL2-associated athanogene 4	1120	0.32
chr1_86598416_86598568	0.47	Cops7b	COP9 signalosome subunit 7B	1752	0.25
chr13_9636658_9636821	0.47	Gm48888	predicted gene, 48888	350	0.86
chr13_46735806_46736396	0.46	Nup153	nucleoporin 153	8161	0.17
chr14_20956319_20956501	0.46	Vcl	vinculin	27012	0.18
chr14_122946058_122946219	0.46	4930594M22Rik	RIKEN cDNA 4930594M22 gene	5981	0.19
chr19_56533975_56534130	0.45	Dclre1a	DNA cross-link repair 1A	3330	0.24
chr7_80635666_80635850	0.45	Gm15880	predicted gene 15880	259	0.9
chr7_70798887_70799067	0.45	Gm24880	predicted gene, 24880	46561	0.15
chr11_95385743_95385947	0.45	Slc35b1	solute carrier family 35, member B1	939	0.38
chr7_128297307_128297458	0.45	BC017158	cDNA sequence BC017158	194	0.88
chr8_125012381_125013106	0.44	Tsnax	translin-associated factor X	254	0.9
chr16_13257357_13257584	0.44	Mrtfb	myocardin related transcription factor B	964	0.67
chr1_130734318_130734676	0.44	AA986860	expressed sequence AA986860	2387	0.14
chr9_31246201_31246667	0.43	Gm7244	predicted gene 7244	28387	0.13
chr1_162859614_162860000	0.43	Fmo1	flavin containing monooxygenase 1	13	0.98
chr9_106756626_106756783	0.43	Rad54l2	RAD54 like 2 (S. cerevisiae)	32472	0.12
chr13_94371154_94371305	0.42	Ap3b1	adaptor-related protein complex 3, beta 1 subunit	12269	0.17
chr18_3960517_3960692	0.42	Gm7378	predicted gene 7378	49652	0.15
chr5_92063540_92063702	0.42	G3bp2	GTPase activating protein (SH3 domain) binding protein 2	3902	0.15
chr13_112466453_112467116	0.41	Il6st	interleukin 6 signal transducer	809	0.59
chr6_28573424_28573621	0.41	Gm37978	predicted gene, 37978	5450	0.18
chr8_116732996_116733152	0.41	Cdyl2	chromodomain protein, Y chromosome-like 2	83	0.98
chr8_54518329_54518486	0.41	Gm45553	predicted gene 45553	4257	0.2
chr16_56551155_56551324	0.41	Abi3bp	ABI gene family, member 3 (NESH) binding protein	73339	0.11
chr6_114089717_114089882	0.40	Gm43932	predicted gene, 43932	27603	0.13
chr2_72222793_72223023	0.40	Rapgef4os2	Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 2	9394	0.17
chr1_93433209_93433360	0.40	Hdlbp	high density lipoprotein (HDL) binding protein	7508	0.12
chr14_27298945_27299301	0.40	Arhgef3	Rho guanine nucleotide exchange factor (GEF) 3	36943	0.16
chr17_12532229_12532396	0.40	Slc22a3	solute carrier family 22 (organic cation transporter), member 3	24608	0.17
chr7_114088442_114088593	0.40	Gm45615	predicted gene 45615	1619	0.45
chr8_109997497_109997880	0.40	Tat	tyrosine aminotransferase	7182	0.12
chr8_46522524_46522828	0.40	Acsl1	acyl-CoA synthetase long-chain family member 1	4110	0.19
chr4_135018164_135018325	0.39	Syf2	SYF2 homolog, RNA splicing factor (S. cerevisiae)	87234	0.06
chr9_121794943_121795277	0.39	Hhatl	hedgehog acyltransferase-like	2603	0.13
chr15_3512657_3512808	0.39	Ghr	growth hormone receptor	41088	0.19
chr9_108297063_108297481	0.38	Amt	aminomethyltransferase	350	0.72
chr8_22878603_22878765	0.38	Gm45555	predicted gene 45555	5095	0.18
chr8_70832381_70832563	0.38	Arrdc2	arrestin domain containing 2	4115	0.09
chr14_34251550_34251824	0.38	Gm18813	predicted gene, 18813	8645	0.09
chr4_108782032_108782195	0.38	Zfyve9	zinc finger, FYVE domain containing 9	1315	0.38
chr5_125323526_125323720	0.38	Gm42633	predicted gene 42633	2179	0.22
chr1_106013874_106014051	0.37	Zcchc2	zinc finger, CCHC domain containing 2	2218	0.27
chr18_54987200_54987598	0.37	Zfp608	zinc finger protein 608	2767	0.26
chr9_30856213_30856364	0.37	Adamts15	a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15	53369	0.12
chr7_19018198_19018349	0.37	Foxa3	forkhead box A3	5265	0.08
chr13_55211103_55211935	0.37	Nsd1	nuclear receptor-binding SET-domain protein 1	22	0.97
chr5_123661837_123661995	0.37	Clip1	CAP-GLY domain containing linker protein 1	4774	0.13
chr8_84147623_84147789	0.36	Cc2d1a	coiled-coil and C2 domain containing 1A	159	0.65
chr6_94163293_94163487	0.36	Magi1	membrane associated guanylate kinase, WW and PDZ domain containing 1	119635	0.06
chr10_122380580_122380731	0.36	Gm36041	predicted gene, 36041	6237	0.25
chr18_84054624_84054776	0.36	Tshz1	teashirt zinc finger family member 1	30375	0.14
chr9_73983069_73983229	0.36	Unc13c	unc-13 homolog C	14183	0.25
chr4_49534864_49535018	0.36	Aldob	aldolase B, fructose-bisphosphate	3925	0.16
chr15_80682694_80682863	0.36	Fam83f	family with sequence similarity 83, member F	10931	0.13
chr8_22934556_22934721	0.36	Kat6a	K(lysine) acetyltransferase 6A	20852	0.14
chr15_59058246_59058397	0.35	Mtss1	MTSS I-BAR domain containing 1	2857	0.31
chr1_78661192_78661343	0.35	Utp14b	UTP14B small subunit processome component	2827	0.23
chr14_16380093_16380270	0.35	Top2b	topoisomerase (DNA) II beta	9396	0.19
chr9_70069929_70070289	0.35	Gm47233	predicted gene, 47233	242	0.89
chr5_52945261_52945434	0.35	Gm23532	predicted gene, 23532	14115	0.15
chr13_29780744_29780904	0.35	Cdkal1	CDK5 regulatory subunit associated protein 1-like 1	74607	0.12
chr19_32798500_32798700	0.35	Pten	phosphatase and tensin homolog	12625	0.25
chr2_152733395_152733571	0.35	Id1	inhibitor of DNA binding 1, HLH protein	2768	0.15
chr3_79219143_79219307	0.35	4921511C10Rik	RIKEN cDNA 4921511C10 gene	6306	0.2
chr1_91444586_91444906	0.35	Per2	period circadian clock 2	5119	0.13
chr1_162860588_162860757	0.35	Fmo1	flavin containing monooxygenase 1	703	0.67
chr2_18415947_18416098	0.34	Dnajc1	DnaJ heat shock protein family (Hsp40) member C1	23192	0.21
chr7_44246179_44246345	0.34	1700028J19Rik	RIKEN cDNA 1700028J19 gene	433	0.26
chr16_91452124_91452326	0.34	Gm46562	predicted gene, 46562	6196	0.1
chr1_105176971_105177328	0.34	Gm29012	predicted gene 29012	60695	0.12
chr13_63231532_63231825	0.34	Aopep	aminopeptidase O	8351	0.11
chr3_51378174_51378338	0.34	Gm5103	predicted gene 5103	180	0.9
chr18_56413923_56414074	0.34	Gramd3	GRAM domain containing 3	5172	0.22
chr2_58789663_58789814	0.34	Upp2	uridine phosphorylase 2	24413	0.18
chr3_10022522_10022722	0.34	Gm38335	predicted gene, 38335	2917	0.22
chr3_28709033_28709184	0.34	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	11091	0.16
chr16_24438794_24438956	0.33	Lpp	LIM domain containing preferred translocation partner in lipoma	9216	0.2
chr2_35385496_35385654	0.33	4930402F06Rik	RIKEN cDNA 4930402F06 gene	11482	0.13
chr12_17376541_17376855	0.33	Mir3066	microRNA 3066	21306	0.14
chr4_108060521_108060686	0.33	Scp2	sterol carrier protein 2, liver	10760	0.13
chr12_54163231_54163399	0.33	Egln3	egl-9 family hypoxia-inducible factor 3	40545	0.13
chr10_28228240_28228413	0.33	Gm22370	predicted gene, 22370	14205	0.29
chr5_147320087_147320238	0.33	Urad	ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase	2278	0.17
chr11_60196823_60197490	0.33	Mir6921	microRNA 6921	3461	0.14
chr3_27127029_27127188	0.32	Ect2	ect2 oncogene	4416	0.19
chr5_43350873_43351056	0.32	Gm43020	predicted gene 43020	4295	0.22
chr16_93932873_93933033	0.32	Cldn14	claudin 14	3136	0.2
chr7_75619069_75619239	0.32	Akap13	A kinase (PRKA) anchor protein 13	4466	0.23
chr19_4148699_4149239	0.32	Coro1b	coronin, actin binding protein 1B	302	0.67
chr1_72871736_72871887	0.32	Igfbp5	insulin-like growth factor binding protein 5	2464	0.32
chr2_166155377_166155528	0.32	Sulf2	sulfatase 2	167	0.95
chr10_127737524_127737721	0.32	Zbtb39	zinc finger and BTB domain containing 39	1916	0.16
chr9_119154224_119154644	0.32	Acaa1b	acetyl-Coenzyme A acyltransferase 1B	2659	0.16
chr8_47673690_47674298	0.32	Ing2	inhibitor of growth family, member 2	305	0.8
chr9_57719905_57720075	0.32	Edc3	enhancer of mRNA decapping 3	11423	0.12
chr8_35630042_35630217	0.32	Mfhas1	malignant fibrous histiocytoma amplified sequence 1	22852	0.17
chr19_29046369_29046553	0.32	1700018L02Rik	RIKEN cDNA 1700018L02 gene	216	0.87
chr19_44393747_44393961	0.32	Scd1	stearoyl-Coenzyme A desaturase 1	12836	0.14
chr6_71160777_71161206	0.31	Gm44427	predicted gene, 44427	3808	0.16
chr9_11315591_11315762	0.31	Gm18934	predicted gene, 18934	37633	0.2
chr1_91437326_91437628	0.31	Per2	period circadian clock 2	12388	0.11
chr11_120236241_120236693	0.31	Bahcc1	BAH domain and coiled-coil containing 1	22	0.83
chr6_54231812_54232155	0.31	Gm15527	predicted gene 15527	22928	0.16
chr18_60747476_60747627	0.31	Rps14	ribosomal protein S14	120	0.91
chr11_69367509_69368033	0.30	Chd3	chromodomain helicase DNA binding protein 3	1620	0.17
chr3_131312138_131312323	0.30	Cyp2u1	cytochrome P450, family 2, subfamily u, polypeptide 1	9003	0.14
chr6_33306096_33306272	0.30	Exoc4	exocyst complex component 4	26171	0.2
chr4_150242219_150242406	0.30	Eno1	enolase 1, alpha non-neuron	1174	0.4
chr6_90334778_90334975	0.30	Uroc1	urocanase domain containing 1	1587	0.25
chr7_100077379_100077530	0.30	Pold3	polymerase (DNA-directed), delta 3, accessory subunit	12583	0.16
chr17_64720655_64720806	0.30	Man2a1	mannosidase 2, alpha 1	7111	0.22
chr2_85048155_85048335	0.30	Tnks1bp1	tankyrase 1 binding protein 1	190	0.9
chr4_141134526_141134677	0.30	Szrd1	SUZ RNA binding domain containing 1	5126	0.12
chr19_26744877_26745028	0.30	Smarca2	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2	257	0.94
chr18_53810810_53810966	0.30	Csnk1g3	casein kinase 1, gamma 3	51234	0.15
chr7_26315480_26315657	0.30	Gm42375	predicted gene, 42375	8282	0.14
chr3_28705261_28705416	0.29	Slc2a2	solute carrier family 2 (facilitated glucose transporter), member 2	7321	0.18
chr4_139386772_139386990	0.29	Ubr4	ubiquitin protein ligase E3 component n-recognin 4	6212	0.12
chr14_63183364_63183533	0.29	Fdft1	farnesyl diphosphate farnesyl transferase 1	3870	0.17
chr9_120009962_120010210	0.29	Gm49427	predicted gene, 49427	281	0.82
chr11_100610223_100610688	0.29	Dnajc7	DnaJ heat shock protein family (Hsp40) member C7	2902	0.14
chr1_65174300_65174494	0.29	Idh1	isocitrate dehydrogenase 1 (NADP+), soluble	1167	0.4
chr11_108308165_108308332	0.29	Apoh	apolipoprotein H	35106	0.15
chr4_43656130_43656321	0.29	Hint2	histidine triad nucleotide binding protein 2	218	0.81
chr3_79809306_79809467	0.29	Gm26420	predicted gene, 26420	25547	0.15
chr11_4229963_4230122	0.29	Gm11956	predicted gene 11956	1223	0.29
chr5_145139980_145140681	0.29	Bud31	BUD31 homolog	32	0.55
chr14_20174882_20175033	0.28	Kcnk5	potassium channel, subfamily K, member 5	6852	0.14
chr2_157130956_157131107	0.28	Samhd1	SAM domain and HD domain, 1	974	0.5
chr9_74848568_74848768	0.28	Gm16551	predicted gene 16551	142	0.58
chr5_8894734_8894942	0.28	Abcb4	ATP-binding cassette, sub-family B (MDR/TAP), member 4	889	0.53
chr1_190117320_190117686	0.28	Gm28172	predicted gene 28172	51167	0.13
chr7_79659672_79659823	0.28	Ticrr	TOPBP1-interacting checkpoint and replication regulator	449	0.73
chr4_131883686_131883871	0.28	Srsf4	serine and arginine-rich splicing factor 4	517	0.65
chr9_21250184_21250335	0.28	S1pr5	sphingosine-1-phosphate receptor 5	1816	0.16
chr13_119389151_119389302	0.28	Nnt	nicotinamide nucleotide transhydrogenase	19726	0.17
chrX_10719688_10719839	0.28	Gm14493	predicted gene 14493	1053	0.45
chr4_117830286_117830539	0.28	Slc6a9	solute carrier family 6 (neurotransmitter transporter, glycine), member 9	4094	0.14
chr18_32557156_32557525	0.28	Gypc	glycophorin C	2640	0.3
chr13_12457474_12457661	0.27	Lgals8	lectin, galactose binding, soluble 8	1044	0.46
chr3_121793319_121793679	0.27	4633401B06Rik	RIKEN cDNA 4633401B06 gene	4927	0.14
chr7_141919332_141919505	0.27	Tollip	toll interacting protein	911	0.5
chr2_118548783_118549158	0.27	Bmf	BCL2 modifying factor	692	0.66
chr5_139775420_139775673	0.27	Ints1	integrator complex subunit 1	92	0.95
chr10_37138598_37138749	0.27	Marcks	myristoylated alanine rich protein kinase C substrate	247	0.81
chr6_85810403_85810557	0.27	Nat8f6	N-acetyltransferase 8 (GCN5-related) family member 6	617	0.53
chr10_67058626_67058777	0.27	Reep3	receptor accessory protein 3	21379	0.17
chr1_88042666_88042990	0.27	AC087801.1	UDP glycosyltransferase 1 family (Ytg1) pseudogene	5228	0.08
chr1_138964147_138964506	0.27	Dennd1b	DENN/MADD domain containing 1B	457	0.64
chr11_95438968_95439128	0.27	Gm11522	predicted gene 11522	23673	0.12
chr15_81394865_81395034	0.27	St13	suppression of tumorigenicity 13	346	0.81
chr10_40300520_40300675	0.27	Amd1	S-adenosylmethionine decarboxylase 1	979	0.41
chr2_26902336_26902522	0.27	Surf6	surfeit gene 6	361	0.69
chr14_47512089_47512243	0.26	Gm35166	predicted gene, 35166	3979	0.14
chr1_162871486_162871643	0.26	Fmo1	flavin containing monooxygenase 1	4954	0.19
chr10_61138290_61138447	0.26	Sgpl1	sphingosine phosphate lyase 1	8530	0.15
chr13_98716100_98716291	0.26	Gm9465	predicted gene 9465	315	0.84
chr11_76997868_76998019	0.26	Slc6a4	solute carrier family 6 (neurotransmitter transporter, serotonin), member 4	660	0.62
chr4_103393218_103393514	0.26	Gm12718	predicted gene 12718	10845	0.2

Histogram of CRE-TSS distances for CREs targeted by :

Rank distribution of CRE target scores:

Distribution of target CREs across different genomic regions:

Network of associatons between targets according to the STRING database.

First level regulatory network of Zscan4c

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0002924	negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.1	0.5	GO:0046121	deoxyribonucleoside catabolic process(GO:0046121)
0.1	0.7	GO:0010606	positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1	0.9	GO:0070995	NADPH oxidation(GO:0070995)
0.1	0.6	GO:1903242	regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1	0.3	GO:0035860	glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1	0.3	GO:0070103	regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1	0.3	GO:0019464	glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1	0.3	GO:0000414	regulation of histone H3-K36 methylation(GO:0000414)
0.1	0.2	GO:1904193	cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1	0.2	GO:0090158	endoplasmic reticulum membrane organization(GO:0090158)
0.1	0.2	GO:0071672	negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1	0.2	GO:0061084	negative regulation of protein refolding(GO:0061084)
0.1	0.2	GO:0006068	ethanol catabolic process(GO:0006068)
0.1	0.3	GO:0042436	tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.1	0.1	GO:0046061	dATP catabolic process(GO:0046061)
0.1	0.2	GO:0061091	regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1	0.2	GO:0033122	negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1	0.2	GO:0072531	pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1	0.2	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.1	0.3	GO:0030174	regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1	0.2	GO:0032079	positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1	0.2	GO:0048696	regulation of collateral sprouting in absence of injury(GO:0048696)
0.1	0.3	GO:0098728	germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1	0.2	GO:0055118	negative regulation of cardiac muscle contraction(GO:0055118)
0.1	0.2	GO:0090365	regulation of mRNA modification(GO:0090365)
0.0	0.2	GO:0045901	positive regulation of translational elongation(GO:0045901)
0.0	0.2	GO:0046618	drug export(GO:0046618)
0.0	0.1	GO:1900106	hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0	0.1	GO:0061368	behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0	0.2	GO:0060696	regulation of phospholipid catabolic process(GO:0060696)
0.0	0.1	GO:1900245	positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0	0.1	GO:0071787	endoplasmic reticulum tubular network assembly(GO:0071787)
0.0	0.1	GO:0006015	5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0	0.2	GO:0042737	drug catabolic process(GO:0042737)
0.0	0.2	GO:0000255	allantoin metabolic process(GO:0000255)
0.0	0.3	GO:0032464	positive regulation of protein homooligomerization(GO:0032464)
0.0	0.1	GO:0070672	response to interleukin-15(GO:0070672)
0.0	0.1	GO:0014734	skeletal muscle hypertrophy(GO:0014734)
0.0	0.1	GO:0090069	regulation of ribosome biogenesis(GO:0090069)
0.0	0.1	GO:0006597	spermine biosynthetic process(GO:0006597)
0.0	0.1	GO:0046167	glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0	0.1	GO:0003062	regulation of heart rate by chemical signal(GO:0003062)
0.0	0.1	GO:0048936	peripheral nervous system neuron axonogenesis(GO:0048936)
0.0	0.1	GO:0019919	peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0	0.2	GO:0032227	negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0	0.1	GO:0030035	microspike assembly(GO:0030035)
0.0	0.1	GO:1990034	calcium ion export from cell(GO:1990034)
0.0	0.0	GO:0031086	nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0	0.1	GO:0072361	regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0	0.1	GO:2000909	regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0	0.1	GO:0003383	apical constriction(GO:0003383)
0.0	0.1	GO:0046104	thymidine metabolic process(GO:0046104)
0.0	0.1	GO:0048003	antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0	0.1	GO:0010046	response to mycotoxin(GO:0010046)
0.0	0.2	GO:0033211	adiponectin-activated signaling pathway(GO:0033211)
0.0	0.1	GO:0051315	attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0	0.1	GO:2001013	epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0	0.1	GO:0002317	plasma cell differentiation(GO:0002317)
0.0	0.1	GO:0097374	sensory neuron axon guidance(GO:0097374)
0.0	0.1	GO:0019478	D-amino acid catabolic process(GO:0019478)
0.0	0.1	GO:0097011	cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0	0.1	GO:0043987	histone H3-S10 phosphorylation(GO:0043987)
0.0	0.3	GO:0031507	heterochromatin assembly(GO:0031507)
0.0	0.3	GO:0034472	snRNA 3'-end processing(GO:0034472)
0.0	0.1	GO:0071883	activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0	0.2	GO:0001547	antral ovarian follicle growth(GO:0001547)
0.0	0.1	GO:0097428	protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0	0.1	GO:0070858	negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0	0.2	GO:1903715	regulation of aerobic respiration(GO:1903715)
0.0	0.1	GO:0035522	monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0	0.0	GO:0060331	negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0	0.1	GO:0010626	negative regulation of Schwann cell proliferation(GO:0010626)
0.0	0.2	GO:0000290	deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0	0.1	GO:1903964	monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0	0.2	GO:0002072	optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0	0.0	GO:0002071	glandular epithelial cell maturation(GO:0002071)
0.0	0.2	GO:0008090	retrograde axonal transport(GO:0008090)
0.0	0.0	GO:0071332	cellular response to fructose stimulus(GO:0071332)
0.0	0.1	GO:0006624	vacuolar protein processing(GO:0006624)
0.0	0.1	GO:0050427	3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0	0.0	GO:0014732	skeletal muscle atrophy(GO:0014732)
0.0	0.1	GO:0044860	protein localization to plasma membrane raft(GO:0044860)
0.0	0.1	GO:1903659	regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0	0.2	GO:0071243	cellular response to arsenic-containing substance(GO:0071243)
0.0	0.1	GO:1900086	positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0	0.1	GO:0036265	RNA (guanine-N7)-methylation(GO:0036265)
0.0	0.5	GO:0048240	sperm capacitation(GO:0048240)
0.0	0.4	GO:0000028	ribosomal small subunit assembly(GO:0000028)
0.0	0.1	GO:1901301	regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0	0.2	GO:0035745	T-helper 2 cell cytokine production(GO:0035745)
0.0	0.1	GO:0071447	cellular response to hydroperoxide(GO:0071447)
0.0	0.1	GO:0010944	negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0	0.1	GO:0071725	response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0	0.1	GO:0006741	NADP biosynthetic process(GO:0006741)
0.0	0.1	GO:1902237	positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0	0.1	GO:0051387	negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0	0.1	GO:0061625	fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0	0.3	GO:0017144	drug metabolic process(GO:0017144)
0.0	0.1	GO:0045040	protein import into mitochondrial outer membrane(GO:0045040)
0.0	0.1	GO:2000015	regulation of determination of dorsal identity(GO:2000015)
0.0	0.1	GO:0031999	negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0	0.0	GO:0043622	cortical microtubule organization(GO:0043622)
0.0	0.1	GO:2000483	negative regulation of interleukin-8 secretion(GO:2000483)
0.0	0.0	GO:0003289	atrial septum primum morphogenesis(GO:0003289)
0.0	0.1	GO:0042989	sequestering of actin monomers(GO:0042989)
0.0	0.1	GO:0048312	intracellular distribution of mitochondria(GO:0048312)
0.0	0.1	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0	0.1	GO:0090074	negative regulation of protein homodimerization activity(GO:0090074)
0.0	0.1	GO:0006477	protein sulfation(GO:0006477)
0.0	0.0	GO:0042505	tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0	0.1	GO:0002125	maternal aggressive behavior(GO:0002125)
0.0	0.1	GO:0006297	nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0	0.1	GO:0071073	positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0	0.0	GO:1902455	negative regulation of stem cell population maintenance(GO:1902455)
0.0	0.0	GO:0021553	olfactory nerve development(GO:0021553)
0.0	0.1	GO:0006013	mannose metabolic process(GO:0006013)
0.0	0.1	GO:0018095	protein polyglutamylation(GO:0018095)
0.0	0.0	GO:0006481	C-terminal protein methylation(GO:0006481)
0.0	0.1	GO:0060023	soft palate development(GO:0060023)
0.0	0.1	GO:1902534	single-organism membrane invagination(GO:1902534)
0.0	0.0	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0	0.0	GO:1900135	positive regulation of renin secretion into blood stream(GO:1900135)
0.0	0.1	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.0	0.0	GO:0072108	positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0	0.2	GO:0042219	cellular modified amino acid catabolic process(GO:0042219)
0.0	0.2	GO:0007216	G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0	0.0	GO:0032696	negative regulation of interleukin-13 production(GO:0032696)
0.0	0.1	GO:0052697	xenobiotic glucuronidation(GO:0052697)
0.0	0.0	GO:0007525	somatic muscle development(GO:0007525)
0.0	0.0	GO:0060300	regulation of cytokine activity(GO:0060300)
0.0	0.0	GO:0045963	negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0	0.3	GO:0090190	positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0	0.1	GO:0070989	oxidative demethylation(GO:0070989)
0.0	0.1	GO:0009404	toxin metabolic process(GO:0009404)
0.0	0.0	GO:1902445	regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0	0.0	GO:0046865	retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0	0.0	GO:1904263	positive regulation of TORC1 signaling(GO:1904263)
0.0	0.1	GO:0006166	purine ribonucleoside salvage(GO:0006166)
0.0	0.2	GO:0007183	SMAD protein complex assembly(GO:0007183)
0.0	0.0	GO:0010901	regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0	0.0	GO:0021564	vagus nerve development(GO:0021564)
0.0	0.0	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0	0.0	GO:0043490	malate-aspartate shuttle(GO:0043490)
0.0	0.1	GO:2000210	positive regulation of anoikis(GO:2000210)
0.0	0.1	GO:0090527	actin filament reorganization(GO:0090527)
0.0	0.0	GO:1900133	regulation of renin secretion into blood stream(GO:1900133)
0.0	0.0	GO:0019086	late viral transcription(GO:0019086)
0.0	0.1	GO:0072386	plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0	0.0	GO:1904154	positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0	0.1	GO:0006498	N-terminal protein lipidation(GO:0006498)
0.0	0.0	GO:1900109	regulation of histone H3-K9 dimethylation(GO:1900109)
0.0	0.1	GO:1904707	positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0	0.0	GO:0070427	nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0	0.2	GO:0001967	suckling behavior(GO:0001967)
0.0	0.1	GO:1900113	negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0	0.0	GO:0015015	heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0	0.1	GO:0032308	positive regulation of prostaglandin secretion(GO:0032308)
0.0	0.1	GO:0051790	short-chain fatty acid biosynthetic process(GO:0051790)
0.0	0.1	GO:1990144	regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0	0.1	GO:0042118	endothelial cell activation(GO:0042118)
0.0	0.0	GO:0098528	skeletal muscle fiber differentiation(GO:0098528)
0.0	0.1	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0	0.1	GO:1990001	inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0	0.2	GO:0048643	positive regulation of skeletal muscle tissue development(GO:0048643)
0.0	0.1	GO:0098908	regulation of neuronal action potential(GO:0098908)
0.0	0.0	GO:0072656	maintenance of protein location in mitochondrion(GO:0072656)
0.0	0.0	GO:0072257	metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0	0.0	GO:0006642	triglyceride mobilization(GO:0006642)
0.0	0.1	GO:0033327	Leydig cell differentiation(GO:0033327)
0.0	0.0	GO:0019626	short-chain fatty acid catabolic process(GO:0019626)
0.0	0.0	GO:0001992	regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0	0.1	GO:0036010	protein localization to endosome(GO:0036010)
0.0	0.5	GO:0032611	interleukin-1 beta production(GO:0032611)
0.0	0.0	GO:1901660	calcium ion export(GO:1901660)
0.0	0.0	GO:0033091	positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0	0.0	GO:0000960	mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0	0.0	GO:0021648	vestibulocochlear nerve morphogenesis(GO:0021648)
0.0	0.0	GO:1901299	negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0	0.2	GO:0007289	spermatid nucleus differentiation(GO:0007289)
0.0	0.1	GO:1902414	protein localization to cell junction(GO:1902414)
0.0	0.0	GO:0061589	calcium activated phosphatidylserine scrambling(GO:0061589)
0.0	0.1	GO:0048341	paraxial mesoderm formation(GO:0048341)
0.0	0.0	GO:0060178	regulation of exocyst localization(GO:0060178)
0.0	0.0	GO:0010248	establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0	0.1	GO:0009052	pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0	0.0	GO:0046292	formaldehyde metabolic process(GO:0046292)
0.0	0.0	GO:1903977	positive regulation of glial cell migration(GO:1903977)
0.0	0.0	GO:1903223	positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0	0.1	GO:0071265	amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0	0.1	GO:0044381	glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0	0.0	GO:0048617	embryonic foregut morphogenesis(GO:0048617)
0.0	0.0	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0007256	activation of JNKK activity(GO:0007256)
0.0	0.1	GO:0002082	regulation of oxidative phosphorylation(GO:0002082)
0.0	0.1	GO:0006089	lactate metabolic process(GO:0006089)
0.0	0.0	GO:1903774	positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0	0.0	GO:0031581	hemidesmosome assembly(GO:0031581)
0.0	0.0	GO:0010040	response to iron(II) ion(GO:0010040)
0.0	0.0	GO:0036481	intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0	0.1	GO:0035089	establishment of apical/basal cell polarity(GO:0035089)
0.0	0.0	GO:0089711	L-glutamate transmembrane transport(GO:0089711)
0.0	0.1	GO:0007016	cytoskeletal anchoring at plasma membrane(GO:0007016)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0005955	calcineurin complex(GO:0005955)
0.1	0.3	GO:0005896	interleukin-6 receptor complex(GO:0005896)
0.1	0.3	GO:0042567	insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1	0.2	GO:0042585	germinal vesicle(GO:0042585)
0.1	0.3	GO:0016602	CCAAT-binding factor complex(GO:0016602)
0.1	0.2	GO:0005642	annulate lamellae(GO:0005642)
0.1	0.9	GO:0030014	CCR4-NOT complex(GO:0030014)
0.0	0.2	GO:0033269	internode region of axon(GO:0033269)
0.0	0.1	GO:0060053	neurofilament cytoskeleton(GO:0060053)
0.0	0.5	GO:0035686	sperm fibrous sheath(GO:0035686)
0.0	0.2	GO:0031315	extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0	0.1	GO:0000942	condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0	0.1	GO:0031074	nucleocytoplasmic shuttling complex(GO:0031074)
0.0	0.2	GO:0005677	chromatin silencing complex(GO:0005677)
0.0	0.2	GO:0001652	granular component(GO:0001652)
0.0	0.1	GO:0002189	ribose phosphate diphosphokinase complex(GO:0002189)
0.0	0.1	GO:0070775	H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0	0.2	GO:0016342	catenin complex(GO:0016342)
0.0	0.2	GO:0032039	integrator complex(GO:0032039)
0.0	0.1	GO:0031618	nuclear pericentric heterochromatin(GO:0031618)
0.0	0.1	GO:0045098	type III intermediate filament(GO:0045098)
0.0	0.1	GO:0097025	MPP7-DLG1-LIN7 complex(GO:0097025)
0.0	0.1	GO:0044316	cone cell pedicle(GO:0044316)
0.0	0.1	GO:0090571	RNA polymerase II transcription repressor complex(GO:0090571)
0.0	0.1	GO:0044352	pinosome(GO:0044352) macropinosome(GO:0044354)
0.0	0.1	GO:0097433	dense body(GO:0097433)
0.0	0.2	GO:0019773	proteasome core complex, alpha-subunit complex(GO:0019773)
0.0	0.2	GO:0046581	intercellular canaliculus(GO:0046581)
0.0	0.1	GO:1990604	IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0	0.1	GO:0035749	myelin sheath adaxonal region(GO:0035749)
0.0	0.1	GO:0097149	centralspindlin complex(GO:0097149)
0.0	0.1	GO:0014701	junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0	0.2	GO:0032426	stereocilium tip(GO:0032426)
0.0	0.1	GO:0033256	I-kappaB/NF-kappaB complex(GO:0033256)
0.0	0.1	GO:0070545	PeBoW complex(GO:0070545)
0.0	0.1	GO:1904115	axon cytoplasm(GO:1904115)
0.0	0.1	GO:0001651	dense fibrillar component(GO:0001651)
0.0	0.1	GO:0097524	sperm plasma membrane(GO:0097524)
0.0	0.0	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	0.0	GO:0000811	GINS complex(GO:0000811)
0.0	0.1	GO:0005916	fascia adherens(GO:0005916)
0.0	0.2	GO:0030867	rough endoplasmic reticulum membrane(GO:0030867)
0.0	0.0	GO:0097441	basilar dendrite(GO:0097441)
0.0	0.1	GO:0035363	histone locus body(GO:0035363)
0.0	0.2	GO:0030123	AP-3 adaptor complex(GO:0030123)
0.0	0.2	GO:0035327	transcriptionally active chromatin(GO:0035327)
0.0	0.0	GO:0033186	CAF-1 complex(GO:0033186)
0.0	0.1	GO:0070852	cell body fiber(GO:0070852)
0.0	0.0	GO:0005958	DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0	0.5	GO:0022627	cytosolic small ribosomal subunit(GO:0022627)
0.0	0.2	GO:0005868	cytoplasmic dynein complex(GO:0005868)
0.0	0.1	GO:0032584	growth cone membrane(GO:0032584)
0.0	0.1	GO:0031083	BLOC-1 complex(GO:0031083)
0.0	0.1	GO:0030126	COPI vesicle coat(GO:0030126)
0.0	0.0	GO:0097513	myosin II filament(GO:0097513)
0.0	0.1	GO:0008024	cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0	0.1	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.0	0.1	GO:0014731	spectrin-associated cytoskeleton(GO:0014731)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	0.7	GO:0033192	calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2	1.4	GO:0004499	N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1	0.3	GO:0008449	N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1	0.4	GO:0046975	histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1	0.3	GO:0032564	dATP binding(GO:0032564)
0.1	0.1	GO:0032554	purine deoxyribonucleotide binding(GO:0032554)
0.1	0.2	GO:0008525	phosphatidylcholine transporter activity(GO:0008525)
0.1	0.4	GO:0031685	adenosine receptor binding(GO:0031685)
0.1	0.2	GO:0004024	alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1	0.8	GO:0004535	poly(A)-specific ribonuclease activity(GO:0004535)
0.1	0.2	GO:1990825	sequence-specific mRNA binding(GO:1990825)
0.1	0.2	GO:0030160	GKAP/Homer scaffold activity(GO:0030160)
0.1	0.2	GO:0004924	oncostatin-M receptor activity(GO:0004924)
0.1	0.6	GO:0016832	aldehyde-lyase activity(GO:0016832)
0.1	0.4	GO:0070181	small ribosomal subunit rRNA binding(GO:0070181)
0.0	0.1	GO:0018479	benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0	0.2	GO:0004083	bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0	0.1	GO:0015222	serotonin transmembrane transporter activity(GO:0015222)
0.0	0.2	GO:0015165	pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0	0.1	GO:0008184	glycogen phosphorylase activity(GO:0008184)
0.0	0.2	GO:0008559	xenobiotic-transporting ATPase activity(GO:0008559)
0.0	0.1	GO:0016971	flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0	0.1	GO:0032051	clathrin light chain binding(GO:0032051)
0.0	0.2	GO:0032795	heterotrimeric G-protein binding(GO:0032795)
0.0	0.1	GO:0055100	adiponectin binding(GO:0055100)
0.0	0.2	GO:0047760	butyrate-CoA ligase activity(GO:0047760)
0.0	0.2	GO:0004769	steroid delta-isomerase activity(GO:0004769)
0.0	0.1	GO:0050501	hyaluronan synthase activity(GO:0050501)
0.0	0.1	GO:0004096	catalase activity(GO:0004096)
0.0	0.1	GO:0005329	dopamine transmembrane transporter activity(GO:0005329)
0.0	0.2	GO:0004768	stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0	0.0	GO:0031893	vasopressin receptor binding(GO:0031893)
0.0	0.1	GO:0004075	biotin carboxylase activity(GO:0004075)
0.0	0.1	GO:0034056	estrogen response element binding(GO:0034056)
0.0	0.1	GO:0019808	polyamine binding(GO:0019808)
0.0	0.1	GO:0004370	glycerol kinase activity(GO:0004370)
0.0	0.1	GO:0004749	ribose phosphate diphosphokinase activity(GO:0004749)
0.0	0.1	GO:0004634	phosphopyruvate hydratase activity(GO:0004634)
0.0	0.6	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0	0.1	GO:0035033	histone deacetylase regulator activity(GO:0035033)
0.0	0.1	GO:0005001	transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0	0.1	GO:0017151	DEAD/H-box RNA helicase binding(GO:0017151)
0.0	0.1	GO:0034186	apolipoprotein A-I binding(GO:0034186)
0.0	0.1	GO:0097493	structural molecule activity conferring elasticity(GO:0097493)
0.0	0.1	GO:0001069	regulatory region RNA binding(GO:0001069)
0.0	0.2	GO:0017070	U6 snRNA binding(GO:0017070)
0.0	0.1	GO:0004833	tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0	0.1	GO:0035242	protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0	0.0	GO:0010484	H3 histone acetyltransferase activity(GO:0010484)
0.0	0.1	GO:0008898	S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0	0.1	GO:0010997	anaphase-promoting complex binding(GO:0010997)
0.0	0.1	GO:0004839	ubiquitin activating enzyme activity(GO:0004839)
0.0	0.1	GO:0016838	carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0	0.1	GO:0016679	oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0	0.1	GO:0005113	patched binding(GO:0005113)
0.0	0.1	GO:0070579	methylcytosine dioxygenase activity(GO:0070579)
0.0	0.1	GO:0047276	N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0	0.1	GO:0050693	LBD domain binding(GO:0050693)
0.0	0.1	GO:2001070	starch binding(GO:2001070)
0.0	0.3	GO:0046966	thyroid hormone receptor binding(GO:0046966)
0.0	0.1	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.0	0.1	GO:0035197	siRNA binding(GO:0035197)
0.0	0.2	GO:0070411	I-SMAD binding(GO:0070411)
0.0	0.1	GO:0019136	deoxynucleoside kinase activity(GO:0019136)
0.0	0.1	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0	0.2	GO:0005159	insulin-like growth factor receptor binding(GO:0005159)
0.0	0.0	GO:0035851	Krueppel-associated box domain binding(GO:0035851)
0.0	0.0	GO:0047961	glycine N-acyltransferase activity(GO:0047961)
0.0	0.0	GO:0015315	hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0	0.1	GO:0097371	MDM2/MDM4 family protein binding(GO:0097371)
0.0	0.1	GO:0005021	vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0	0.2	GO:0008607	phosphorylase kinase regulator activity(GO:0008607)
0.0	0.1	GO:0047105	aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0	0.1	GO:0042134	rRNA primary transcript binding(GO:0042134)
0.0	0.4	GO:0015485	cholesterol binding(GO:0015485)
0.0	0.1	GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0	0.1	GO:0016744	transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0	0.1	GO:0005332	gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0	0.1	GO:0019992	diacylglycerol binding(GO:0019992)
0.0	0.0	GO:0097016	L27 domain binding(GO:0097016)
0.0	0.2	GO:0030332	cyclin binding(GO:0030332)
0.0	0.1	GO:0035325	Toll-like receptor binding(GO:0035325)
0.0	0.0	GO:0030899	calcium-dependent ATPase activity(GO:0030899)
0.0	0.1	GO:0070891	lipoteichoic acid binding(GO:0070891)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.6	GO:0005080	protein kinase C binding(GO:0005080)
0.0	0.0	GO:0019961	interferon binding(GO:0019961)
0.0	0.2	GO:0003785	actin monomer binding(GO:0003785)
0.0	0.0	GO:0008384	IkappaB kinase activity(GO:0008384)
0.0	0.0	GO:0008970	phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0	0.4	GO:0051059	NF-kappaB binding(GO:0051059)
0.0	0.1	GO:0002162	dystroglycan binding(GO:0002162)
0.0	0.1	GO:0005381	iron ion transmembrane transporter activity(GO:0005381)
0.0	0.0	GO:0030350	iron-responsive element binding(GO:0030350)
0.0	0.1	GO:0004311	farnesyltranstransferase activity(GO:0004311)
0.0	0.0	GO:0004013	adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0	0.0	GO:0070573	metallodipeptidase activity(GO:0070573)
0.0	0.0	GO:0019166	trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0	0.0	GO:0015183	L-aspartate transmembrane transporter activity(GO:0015183)
0.0	0.0	GO:0019834	phospholipase A2 inhibitor activity(GO:0019834)
0.0	0.1	GO:0008093	cytoskeletal adaptor activity(GO:0008093)
0.0	0.3	GO:0052771	coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0	0.0	GO:0016421	CoA carboxylase activity(GO:0016421)
0.0	0.0	GO:0004719	protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0	0.0	GO:0015375	glycine:sodium symporter activity(GO:0015375)
0.0	0.0	GO:0003976	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0	0.1	GO:0005324	long-chain fatty acid transporter activity(GO:0005324)
0.0	0.0	GO:0004920	interleukin-10 receptor activity(GO:0004920)

Gene overrepresentation in curated gene sets: canonical pathways category:

Total log-likelihood	Term	Description
0.2	PID P38 GAMMA DELTA PATHWAY	Signaling mediated by p38-gamma and p38-delta
0.6	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.2	ST STAT3 PATHWAY	STAT3 Pathway
0.3	PID IL27 PATHWAY	IL27-mediated signaling events
0.1	SA CASPASE CASCADE	Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.6	PID ECADHERIN STABILIZATION PATHWAY	Stabilization and expansion of the E-cadherin adherens junction
0.1	PID BMP PATHWAY	BMP receptor signaling
0.1	PID FAK PATHWAY	Signaling events mediated by focal adhesion kinase
0.2	PID ARF6 DOWNSTREAM PATHWAY	Arf6 downstream pathway
0.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	PID THROMBIN PAR1 PATHWAY	PAR1-mediated thrombin signaling events
0.1	PID ANTHRAX PATHWAY	Cellular roles of Anthrax toxin
0.3	PID HIV NEF PATHWAY	HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.2	PID ALK1 PATHWAY	ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.1	REACTOME TRIGLYCERIDE BIOSYNTHESIS	Genes involved in Triglyceride Biosynthesis
0.1	0.4	REACTOME ETHANOL OXIDATION	Genes involved in Ethanol oxidation
0.1	0.5	REACTOME TRYPTOPHAN CATABOLISM	Genes involved in Tryptophan catabolism
0.0	0.3	REACTOME ABACAVIR TRANSPORT AND METABOLISM	Genes involved in Abacavir transport and metabolism
0.0	0.4	REACTOME ROLE OF DCC IN REGULATING APOPTOSIS	Genes involved in Role of DCC in regulating apoptosis
0.0	0.3	REACTOME IL 6 SIGNALING	Genes involved in Interleukin-6 signaling
0.0	1.2	REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS	Genes involved in Phase 1 - Functionalization of compounds
0.0	0.6	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.2	REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS	Genes involved in Ionotropic activity of Kainate Receptors
0.0	0.3	REACTOME ACTIVATION OF BH3 ONLY PROTEINS	Genes involved in Activation of BH3-only proteins
0.0	0.1	REACTOME RNA POL I PROMOTER OPENING	Genes involved in RNA Polymerase I Promoter Opening
0.0	0.3	REACTOME DEADENYLATION OF MRNA	Genes involved in Deadenylation of mRNA
0.0	0.3	REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS	Genes involved in ABCA transporters in lipid homeostasis
0.0	0.2	REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS	Genes involved in Glycogen breakdown (glycogenolysis)
0.0	0.3	REACTOME SIGNALING BY BMP	Genes involved in Signaling by BMP
0.0	0.1	REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION	Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0	0.2	REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP	Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0	0.2	REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE	Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0	0.1	REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS	Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0	0.1	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.0	0.5	REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX	Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0	0.2	REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS	Genes involved in Nucleotide-like (purinergic) receptors
0.0	0.1	REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR	Genes involved in Trafficking and processing of endosomal TLR