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ENCSR904DTN: DNase-seq of mouse liver in constant darkness
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Results for Zscan4c

Z-value: 1.77

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Transcription factors associated with Zscan4c

Gene Symbol Gene ID Gene Info
Zscan4c
ENSMUSG00000054272.5 zinc finger and SCAN domain containing 4C

Activity of the Zscan4c motif across conditions

Conditions sorted by the z-value of the Zscan4c motif activity

Move your cursor over a bar to see sample name and corresponding Z-value.

Top target CREs of the motif:

Cis Regulatory Element (CRE) Target Score Top associated gene Gene Info Distance of CRE to TSS CRE/Gene association probability
chr18_12732086_12732318 2.30 Ttc39c
 tetratricopeptide repeat domain 39C
 2503
 0.2
chr18_12731812_12732024 1.23 Ttc39c
 tetratricopeptide repeat domain 39C
 2787
 0.19
chr5_38117047_38117323 1.04 Stx18
 syntaxin 18
 3724
 0.2
chr9_122119702_122119865 1.02 Gm47122
 predicted gene, 47122
 638
 0.56
chr1_162966082_162966252 0.99 Gm37273
 predicted gene, 37273
 16847
 0.15
chr11_117831026_117831177 0.92 Afmid
 arylformamidase
 1003
 0.31
chr9_44387040_44387229 0.86 Hyou1
 hypoxia up-regulated 1
 3527
 0.07
chr3_138233542_138233745 0.84 Adh7
 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
 5592
 0.13
chr5_27996032_27996183 0.82 Gm4865
 predicted gene 4865
 5199
 0.19
chr16_90199102_90199289 0.77 Gm49704
 predicted gene, 49704
 1047
 0.47
chr17_64644726_64644989 0.75 Man2a1
 mannosidase 2, alpha 1
 44121
 0.17
chr18_49980030_49980460 0.75 Tnfaip8
 tumor necrosis factor, alpha-induced protein 8
 710
 0.72
chr1_182763696_182764002 0.73 Susd4
 sushi domain containing 4
 11
 0.98
chr11_110177974_110178125 0.70 Abca9
 ATP-binding cassette, sub-family A (ABC1), member 9
 9853
 0.25
chr5_96161523_96161844 0.68 Cnot6l
 CCR4-NOT transcription complex, subunit 6-like
 59
 0.98
chr3_136670359_136670659 0.68 Ppp3ca
 protein phosphatase 3, catalytic subunit, alpha isoform
 261
 0.94
chr4_106763916_106764094 0.68 Acot11
 acyl-CoA thioesterase 11
 7551
 0.15
chr3_97645418_97646002 0.67 Prkab2
 protein kinase, AMP-activated, beta 2 non-catalytic subunit
 12483
 0.13
chr9_30820894_30821215 0.67 Gm31013
 predicted gene, 31013
 39575
 0.16
chr1_127730419_127730668 0.63 Acmsd
 amino carboxymuconate semialdehyde decarboxylase
 1130
 0.5
chr7_126273472_126273659 0.63 Sbk1
 SH3-binding kinase 1
 165
 0.92
chr8_117316911_117317193 0.58 Cmip
 c-Maf inducing protein
 32118
 0.2
chr13_34635371_34635522 0.57 Pxdc1
 PX domain containing 1
 13122
 0.13
chr11_81371218_81371402 0.56 4930527B05Rik
 RIKEN cDNA 4930527B05 gene
 13703
 0.29
chr19_38399310_38399568 0.56 Slc35g1
 solute carrier family 35, member G1
 3398
 0.2
chr9_44083899_44084207 0.56 Usp2
 ubiquitin specific peptidase 2
 886
 0.32
chr13_60664706_60665228 0.55 Gm48583
 predicted gene, 48583
 23177
 0.15
chrX_94541280_94541431 0.55 Maged1
 melanoma antigen, family D, 1
 635
 0.62
chr6_137797018_137797169 0.54 Dera
 deoxyribose-phosphate aldolase (putative)
 259
 0.94
chr3_31970158_31970309 0.53 Gm37834
 predicted gene, 37834
 15469
 0.27
chr1_155808676_155809110 0.53 Qsox1
 quiescin Q6 sulfhydryl oxidase 1
 3927
 0.15
chr17_57056615_57056782 0.53 Slc25a23
 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
 1313
 0.19
chrX_85734642_85734808 0.51 Gk
 glycerol kinase
 2885
 0.21
chr16_24517847_24518116 0.51 Morf4l1-ps1
 mortality factor 4 like 1, pseudogene 1
 11413
 0.25
chr1_154117784_154118141 0.50 A830008E24Rik
 RIKEN cDNA A830008E24 gene
 11
 0.98
chr6_136449342_136449720 0.50 Gm25882
 predicted gene, 25882
 31719
 0.1
chr11_110496442_110496593 0.49 Map2k6
 mitogen-activated protein kinase kinase 6
 17478
 0.25
chr10_80674829_80675669 0.48 Mknk2
 MAP kinase-interacting serine/threonine kinase 2
 1044
 0.31
chr3_130999761_130999912 0.48 A430072C10Rik
 RIKEN cDNA A430072C10 gene
 26534
 0.14
chr5_25015695_25015994 0.47 Prkag2
 protein kinase, AMP-activated, gamma 2 non-catalytic subunit
 20091
 0.17
chr8_25776385_25776540 0.47 Bag4
 BCL2-associated athanogene 4
 1120
 0.32
chr1_86598416_86598568 0.47 Cops7b
 COP9 signalosome subunit 7B
 1752
 0.25
chr13_9636658_9636821 0.47 Gm48888
 predicted gene, 48888
 350
 0.86
chr13_46735806_46736396 0.46 Nup153
 nucleoporin 153
 8161
 0.17
chr14_20956319_20956501 0.46 Vcl
 vinculin
 27012
 0.18
chr14_122946058_122946219 0.46 4930594M22Rik
 RIKEN cDNA 4930594M22 gene
 5981
 0.19
chr19_56533975_56534130 0.45 Dclre1a
 DNA cross-link repair 1A
 3330
 0.24
chr7_80635666_80635850 0.45 Gm15880
 predicted gene 15880
 259
 0.9
chr7_70798887_70799067 0.45 Gm24880
 predicted gene, 24880
 46561
 0.15
chr11_95385743_95385947 0.45 Slc35b1
 solute carrier family 35, member B1
 939
 0.38
chr7_128297307_128297458 0.45 BC017158
 cDNA sequence BC017158
 194
 0.88
chr8_125012381_125013106 0.44 Tsnax
 translin-associated factor X
 254
 0.9
chr16_13257357_13257584 0.44 Mrtfb
 myocardin related transcription factor B
 964
 0.67
chr1_130734318_130734676 0.44 AA986860
 expressed sequence AA986860
 2387
 0.14
chr9_31246201_31246667 0.43 Gm7244
 predicted gene 7244
 28387
 0.13
chr1_162859614_162860000 0.43 Fmo1
 flavin containing monooxygenase 1
 13
 0.98
chr9_106756626_106756783 0.43 Rad54l2
 RAD54 like 2 (S. cerevisiae)
 32472
 0.12
chr13_94371154_94371305 0.42 Ap3b1
 adaptor-related protein complex 3, beta 1 subunit
 12269
 0.17
chr18_3960517_3960692 0.42 Gm7378
 predicted gene 7378
 49652
 0.15
chr5_92063540_92063702 0.42 G3bp2
 GTPase activating protein (SH3 domain) binding protein 2
 3902
 0.15
chr13_112466453_112467116 0.41 Il6st
 interleukin 6 signal transducer
 809
 0.59
chr6_28573424_28573621 0.41 Gm37978
 predicted gene, 37978
 5450
 0.18
chr8_116732996_116733152 0.41 Cdyl2
 chromodomain protein, Y chromosome-like 2
 83
 0.98
chr8_54518329_54518486 0.41 Gm45553
 predicted gene 45553
 4257
 0.2
chr16_56551155_56551324 0.41 Abi3bp
 ABI gene family, member 3 (NESH) binding protein
 73339
 0.11
chr6_114089717_114089882 0.40 Gm43932
 predicted gene, 43932
 27603
 0.13
chr2_72222793_72223023 0.40 Rapgef4os2
 Rap guanine nucleotide exchange factor (GEF) 4, opposite strand 2
 9394
 0.17
chr1_93433209_93433360 0.40 Hdlbp
 high density lipoprotein (HDL) binding protein
 7508
 0.12
chr14_27298945_27299301 0.40 Arhgef3
 Rho guanine nucleotide exchange factor (GEF) 3
 36943
 0.16
chr17_12532229_12532396 0.40 Slc22a3
 solute carrier family 22 (organic cation transporter), member 3
 24608
 0.17
chr7_114088442_114088593 0.40 Gm45615
 predicted gene 45615
 1619
 0.45
chr8_109997497_109997880 0.40 Tat
 tyrosine aminotransferase
 7182
 0.12
chr8_46522524_46522828 0.40 Acsl1
 acyl-CoA synthetase long-chain family member 1
 4110
 0.19
chr4_135018164_135018325 0.39 Syf2
 SYF2 homolog, RNA splicing factor (S. cerevisiae)
 87234
 0.06
chr9_121794943_121795277 0.39 Hhatl
 hedgehog acyltransferase-like
 2603
 0.13
chr15_3512657_3512808 0.39 Ghr
 growth hormone receptor
 41088
 0.19
chr9_108297063_108297481 0.38 Amt
 aminomethyltransferase
 350
 0.72
chr8_22878603_22878765 0.38 Gm45555
 predicted gene 45555
 5095
 0.18
chr8_70832381_70832563 0.38 Arrdc2
 arrestin domain containing 2
 4115
 0.09
chr14_34251550_34251824 0.38 Gm18813
 predicted gene, 18813
 8645
 0.09
chr4_108782032_108782195 0.38 Zfyve9
 zinc finger, FYVE domain containing 9
 1315
 0.38
chr5_125323526_125323720 0.38 Gm42633
 predicted gene 42633
 2179
 0.22
chr1_106013874_106014051 0.37 Zcchc2
 zinc finger, CCHC domain containing 2
 2218
 0.27
chr18_54987200_54987598 0.37 Zfp608
 zinc finger protein 608
 2767
 0.26
chr9_30856213_30856364 0.37 Adamts15
 a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 15
 53369
 0.12
chr7_19018198_19018349 0.37 Foxa3
 forkhead box A3
 5265
 0.08
chr13_55211103_55211935 0.37 Nsd1
 nuclear receptor-binding SET-domain protein 1
 22
 0.97
chr5_123661837_123661995 0.37 Clip1
 CAP-GLY domain containing linker protein 1
 4774
 0.13
chr8_84147623_84147789 0.36 Cc2d1a
 coiled-coil and C2 domain containing 1A
 159
 0.65
chr6_94163293_94163487 0.36 Magi1
 membrane associated guanylate kinase, WW and PDZ domain containing 1
 119635
 0.06
chr10_122380580_122380731 0.36 Gm36041
 predicted gene, 36041
 6237
 0.25
chr18_84054624_84054776 0.36 Tshz1
 teashirt zinc finger family member 1
 30375
 0.14
chr9_73983069_73983229 0.36 Unc13c
 unc-13 homolog C
 14183
 0.25
chr4_49534864_49535018 0.36 Aldob
 aldolase B, fructose-bisphosphate
 3925
 0.16
chr15_80682694_80682863 0.36 Fam83f
 family with sequence similarity 83, member F
 10931
 0.13
chr8_22934556_22934721 0.36 Kat6a
 K(lysine) acetyltransferase 6A
 20852
 0.14
chr15_59058246_59058397 0.35 Mtss1
 MTSS I-BAR domain containing 1
 2857
 0.31
chr1_78661192_78661343 0.35 Utp14b
 UTP14B small subunit processome component
 2827
 0.23
chr14_16380093_16380270 0.35 Top2b
 topoisomerase (DNA) II beta
 9396
 0.19
chr9_70069929_70070289 0.35 Gm47233
 predicted gene, 47233
 242
 0.89
chr5_52945261_52945434 0.35 Gm23532
 predicted gene, 23532
 14115
 0.15
chr13_29780744_29780904 0.35 Cdkal1
 CDK5 regulatory subunit associated protein 1-like 1
 74607
 0.12
chr19_32798500_32798700 0.35 Pten
 phosphatase and tensin homolog
 12625
 0.25
chr2_152733395_152733571 0.35 Id1
 inhibitor of DNA binding 1, HLH protein
 2768
 0.15
chr3_79219143_79219307 0.35 4921511C10Rik
 RIKEN cDNA 4921511C10 gene
 6306
 0.2
chr1_91444586_91444906 0.35 Per2
 period circadian clock 2
 5119
 0.13
chr1_162860588_162860757 0.35 Fmo1
 flavin containing monooxygenase 1
 703
 0.67
chr2_18415947_18416098 0.34 Dnajc1
 DnaJ heat shock protein family (Hsp40) member C1
 23192
 0.21
chr7_44246179_44246345 0.34 1700028J19Rik
 RIKEN cDNA 1700028J19 gene
 433
 0.26
chr16_91452124_91452326 0.34 Gm46562
 predicted gene, 46562
 6196
 0.1
chr1_105176971_105177328 0.34 Gm29012
 predicted gene 29012
 60695
 0.12
chr13_63231532_63231825 0.34 Aopep
 aminopeptidase O
 8351
 0.11
chr3_51378174_51378338 0.34 Gm5103
 predicted gene 5103
 180
 0.9
chr18_56413923_56414074 0.34 Gramd3
 GRAM domain containing 3
 5172
 0.22
chr2_58789663_58789814 0.34 Upp2
 uridine phosphorylase 2
 24413
 0.18
chr3_10022522_10022722 0.34 Gm38335
 predicted gene, 38335
 2917
 0.22
chr3_28709033_28709184 0.34 Slc2a2
 solute carrier family 2 (facilitated glucose transporter), member 2
 11091
 0.16
chr16_24438794_24438956 0.33 Lpp
 LIM domain containing preferred translocation partner in lipoma
 9216
 0.2
chr2_35385496_35385654 0.33 4930402F06Rik
 RIKEN cDNA 4930402F06 gene
 11482
 0.13
chr12_17376541_17376855 0.33 Mir3066
 microRNA 3066
 21306
 0.14
chr4_108060521_108060686 0.33 Scp2
 sterol carrier protein 2, liver
 10760
 0.13
chr12_54163231_54163399 0.33 Egln3
 egl-9 family hypoxia-inducible factor 3
 40545
 0.13
chr10_28228240_28228413 0.33 Gm22370
 predicted gene, 22370
 14205
 0.29
chr5_147320087_147320238 0.33 Urad
 ureidoimidazoline (2-oxo-4-hydroxy-4-carboxy-5) decarboxylase
 2278
 0.17
chr11_60196823_60197490 0.33 Mir6921
 microRNA 6921
 3461
 0.14
chr3_27127029_27127188 0.32 Ect2
 ect2 oncogene
 4416
 0.19
chr5_43350873_43351056 0.32 Gm43020
 predicted gene 43020
 4295
 0.22
chr16_93932873_93933033 0.32 Cldn14
 claudin 14
 3136
 0.2
chr7_75619069_75619239 0.32 Akap13
 A kinase (PRKA) anchor protein 13
 4466
 0.23
chr19_4148699_4149239 0.32 Coro1b
 coronin, actin binding protein 1B
 302
 0.67
chr1_72871736_72871887 0.32 Igfbp5
 insulin-like growth factor binding protein 5
 2464
 0.32
chr2_166155377_166155528 0.32 Sulf2
 sulfatase 2
 167
 0.95
chr10_127737524_127737721 0.32 Zbtb39
 zinc finger and BTB domain containing 39
 1916
 0.16
chr9_119154224_119154644 0.32 Acaa1b
 acetyl-Coenzyme A acyltransferase 1B
 2659
 0.16
chr8_47673690_47674298 0.32 Ing2
 inhibitor of growth family, member 2
 305
 0.8
chr9_57719905_57720075 0.32 Edc3
 enhancer of mRNA decapping 3
 11423
 0.12
chr8_35630042_35630217 0.32 Mfhas1
 malignant fibrous histiocytoma amplified sequence 1
 22852
 0.17
chr19_29046369_29046553 0.32 1700018L02Rik
 RIKEN cDNA 1700018L02 gene
 216
 0.87
chr19_44393747_44393961 0.32 Scd1
 stearoyl-Coenzyme A desaturase 1
 12836
 0.14
chr6_71160777_71161206 0.31 Gm44427
 predicted gene, 44427
 3808
 0.16
chr9_11315591_11315762 0.31 Gm18934
 predicted gene, 18934
 37633
 0.2
chr1_91437326_91437628 0.31 Per2
 period circadian clock 2
 12388
 0.11
chr11_120236241_120236693 0.31 Bahcc1
 BAH domain and coiled-coil containing 1
 22
 0.83
chr6_54231812_54232155 0.31 Gm15527
 predicted gene 15527
 22928
 0.16
chr18_60747476_60747627 0.31 Rps14
 ribosomal protein S14
 120
 0.91
chr11_69367509_69368033 0.30 Chd3
 chromodomain helicase DNA binding protein 3
 1620
 0.17
chr3_131312138_131312323 0.30 Cyp2u1
 cytochrome P450, family 2, subfamily u, polypeptide 1
 9003
 0.14
chr6_33306096_33306272 0.30 Exoc4
 exocyst complex component 4
 26171
 0.2
chr4_150242219_150242406 0.30 Eno1
 enolase 1, alpha non-neuron
 1174
 0.4
chr6_90334778_90334975 0.30 Uroc1
 urocanase domain containing 1
 1587
 0.25
chr7_100077379_100077530 0.30 Pold3
 polymerase (DNA-directed), delta 3, accessory subunit
 12583
 0.16
chr17_64720655_64720806 0.30 Man2a1
 mannosidase 2, alpha 1
 7111
 0.22
chr2_85048155_85048335 0.30 Tnks1bp1
 tankyrase 1 binding protein 1
 190
 0.9
chr4_141134526_141134677 0.30 Szrd1
 SUZ RNA binding domain containing 1
 5126
 0.12
chr19_26744877_26745028 0.30 Smarca2
 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
 257
 0.94
chr18_53810810_53810966 0.30 Csnk1g3
 casein kinase 1, gamma 3
 51234
 0.15
chr7_26315480_26315657 0.30 Gm42375
 predicted gene, 42375
 8282
 0.14
chr3_28705261_28705416 0.29 Slc2a2
 solute carrier family 2 (facilitated glucose transporter), member 2
 7321
 0.18
chr4_139386772_139386990 0.29 Ubr4
 ubiquitin protein ligase E3 component n-recognin 4
 6212
 0.12
chr14_63183364_63183533 0.29 Fdft1
 farnesyl diphosphate farnesyl transferase 1
 3870
 0.17
chr9_120009962_120010210 0.29 Gm49427
 predicted gene, 49427
 281
 0.82
chr11_100610223_100610688 0.29 Dnajc7
 DnaJ heat shock protein family (Hsp40) member C7
 2902
 0.14
chr1_65174300_65174494 0.29 Idh1
 isocitrate dehydrogenase 1 (NADP+), soluble
 1167
 0.4
chr11_108308165_108308332 0.29 Apoh
 apolipoprotein H
 35106
 0.15
chr4_43656130_43656321 0.29 Hint2
 histidine triad nucleotide binding protein 2
 218
 0.81
chr3_79809306_79809467 0.29 Gm26420
 predicted gene, 26420
 25547
 0.15
chr11_4229963_4230122 0.29 Gm11956
 predicted gene 11956
 1223
 0.29
chr5_145139980_145140681 0.29 Bud31
 BUD31 homolog
 32
 0.55
chr14_20174882_20175033 0.28 Kcnk5
 potassium channel, subfamily K, member 5
 6852
 0.14
chr2_157130956_157131107 0.28 Samhd1
 SAM domain and HD domain, 1
 974
 0.5
chr9_74848568_74848768 0.28 Gm16551
 predicted gene 16551
 142
 0.58
chr5_8894734_8894942 0.28 Abcb4
 ATP-binding cassette, sub-family B (MDR/TAP), member 4
 889
 0.53
chr1_190117320_190117686 0.28 Gm28172
 predicted gene 28172
 51167
 0.13
chr7_79659672_79659823 0.28 Ticrr
 TOPBP1-interacting checkpoint and replication regulator
 449
 0.73
chr4_131883686_131883871 0.28 Srsf4
 serine and arginine-rich splicing factor 4
 517
 0.65
chr9_21250184_21250335 0.28 S1pr5
 sphingosine-1-phosphate receptor 5
 1816
 0.16
chr13_119389151_119389302 0.28 Nnt
 nicotinamide nucleotide transhydrogenase
 19726
 0.17
chrX_10719688_10719839 0.28 Gm14493
 predicted gene 14493
 1053
 0.45
chr4_117830286_117830539 0.28 Slc6a9
 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
 4094
 0.14
chr18_32557156_32557525 0.28 Gypc
 glycophorin C
 2640
 0.3
chr13_12457474_12457661 0.27 Lgals8
 lectin, galactose binding, soluble 8
 1044
 0.46
chr3_121793319_121793679 0.27 4633401B06Rik
 RIKEN cDNA 4633401B06 gene
 4927
 0.14
chr7_141919332_141919505 0.27 Tollip
 toll interacting protein
 911
 0.5
chr2_118548783_118549158 0.27 Bmf
 BCL2 modifying factor
 692
 0.66
chr5_139775420_139775673 0.27 Ints1
 integrator complex subunit 1
 92
 0.95
chr10_37138598_37138749 0.27 Marcks
 myristoylated alanine rich protein kinase C substrate
 247
 0.81
chr6_85810403_85810557 0.27 Nat8f6
 N-acetyltransferase 8 (GCN5-related) family member 6
 617
 0.53
chr10_67058626_67058777 0.27 Reep3
 receptor accessory protein 3
 21379
 0.17
chr1_88042666_88042990 0.27 AC087801.1
 UDP glycosyltransferase 1 family (Ytg1) pseudogene
 5228
 0.08
chr1_138964147_138964506 0.27 Dennd1b
 DENN/MADD domain containing 1B
 457
 0.64
chr11_95438968_95439128 0.27 Gm11522
 predicted gene 11522
 23673
 0.12
chr15_81394865_81395034 0.27 St13
 suppression of tumorigenicity 13
 346
 0.81
chr10_40300520_40300675 0.27 Amd1
 S-adenosylmethionine decarboxylase 1
 979
 0.41
chr2_26902336_26902522 0.27 Surf6
 surfeit gene 6
 361
 0.69
chr14_47512089_47512243 0.26 Gm35166
 predicted gene, 35166
 3979
 0.14
chr1_162871486_162871643 0.26 Fmo1
 flavin containing monooxygenase 1
 4954
 0.19
chr10_61138290_61138447 0.26 Sgpl1
 sphingosine phosphate lyase 1
 8530
 0.15
chr13_98716100_98716291 0.26 Gm9465
 predicted gene 9465
 315
 0.84
chr11_76997868_76998019 0.26 Slc6a4
 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4
 660
 0.62
chr4_103393218_103393514 0.26 Gm12718
 predicted gene 12718
 10845
 0.2

Histogram of CRE-TSS distances for CREs targeted by :

Histogram of

Rank distribution of CRE target scores:

Histogram of target CRE score.

Distribution of target CREs across different genomic regions:

Weighted Piechart of Weighted Piechart of Weighted Piechart of

Network of associatons between targets according to the STRING database.

First level regulatory network of Zscan4c

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.1 0.5 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.7 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.1 0.9 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:1903242 regulation of cardiac muscle adaptation(GO:0010612) regulation of cardiac muscle hypertrophy in response to stress(GO:1903242)
0.1 0.3 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
0.1 0.3 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1 0.3 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.2 GO:1904193 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.1 0.2 GO:0090158 endoplasmic reticulum membrane organization(GO:0090158)
0.1 0.2 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1 0.2 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.1 0.2 GO:0006068 ethanol catabolic process(GO:0006068)
0.1 0.3 GO:0042436 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218)
0.1 0.1 GO:0046061 dATP catabolic process(GO:0046061)
0.1 0.2 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.2 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.1 0.2 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.1 0.3 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.2 GO:0032079 positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.1 0.2 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.3 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.2 GO:0055118 negative regulation of cardiac muscle contraction(GO:0055118)
0.1 0.2 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.2 GO:0045901 positive regulation of translational elongation(GO:0045901)
0.0 0.2 GO:0046618 drug export(GO:0046618)
0.0 0.1 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0060696 regulation of phospholipid catabolic process(GO:0060696)
0.0 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.1 GO:0006015 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.0 0.2 GO:0042737 drug catabolic process(GO:0042737)
0.0 0.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.1 GO:0090069 regulation of ribosome biogenesis(GO:0090069)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.1 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.0 0.1 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.1 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.0 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.1 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0031086 nuclear-transcribed mRNA catabolic process, deadenylation-independent decay(GO:0031086) deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361)
0.0 0.1 GO:2000909 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:0046104 thymidine metabolic process(GO:0046104)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0010046 response to mycotoxin(GO:0010046)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.1 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.0 0.1 GO:2001013 epithelial cell proliferation involved in renal tubule morphogenesis(GO:2001013)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.1 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.0 0.1 GO:0019478 D-amino acid catabolic process(GO:0019478)
0.0 0.1 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011)
0.0 0.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0001547 antral ovarian follicle growth(GO:0001547)
0.0 0.1 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.2 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.0 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.1 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.1 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0002072 optic cup morphogenesis involved in camera-type eye development(GO:0002072)
0.0 0.0 GO:0002071 glandular epithelial cell maturation(GO:0002071)
0.0 0.2 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.0 GO:0071332 cellular response to fructose stimulus(GO:0071332)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 0.1 GO:0050427 3'-phosphoadenosine 5'-phosphosulfate metabolic process(GO:0050427)
0.0 0.0 GO:0014732 skeletal muscle atrophy(GO:0014732)
0.0 0.1 GO:0044860 protein localization to plasma membrane raft(GO:0044860)
0.0 0.1 GO:1903659 regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.2 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.1 GO:1900086 positive regulation of peptidyl-tyrosine autophosphorylation(GO:1900086)
0.0 0.1 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.1 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0061625 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624) glycolytic process through fructose-1-phosphate(GO:0061625)
0.0 0.3 GO:0017144 drug metabolic process(GO:0017144)
0.0 0.1 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.1 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.0 0.1 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.0 0.0 GO:0043622 cortical microtubule organization(GO:0043622)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.0 GO:0003289 atrial septum primum morphogenesis(GO:0003289)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.0 GO:0042505 tyrosine phosphorylation of Stat6 protein(GO:0042505) regulation of tyrosine phosphorylation of Stat6 protein(GO:0042525)
0.0 0.1 GO:0002125 maternal aggressive behavior(GO:0002125)
0.0 0.1 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.0 0.1 GO:0071073 positive regulation of phospholipid biosynthetic process(GO:0071073)
0.0 0.0 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.0 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.1 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.0 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1902534 single-organism membrane invagination(GO:1902534)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.0 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.0 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.2 GO:0042219 cellular modified amino acid catabolic process(GO:0042219)
0.0 0.2 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.0 0.0 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.1 GO:0052697 xenobiotic glucuronidation(GO:0052697)
0.0 0.0 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.0 GO:0060300 regulation of cytokine activity(GO:0060300)
0.0 0.0 GO:0045963 negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963)
0.0 0.3 GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis(GO:0090190)
0.0 0.1 GO:0070989 oxidative demethylation(GO:0070989)
0.0 0.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.0 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.0 0.0 GO:0046865 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865)
0.0 0.0 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0006166 purine ribonucleoside salvage(GO:0006166)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.0 GO:0010901 regulation of very-low-density lipoprotein particle remodeling(GO:0010901)
0.0 0.0 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.0 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.0 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.0 GO:1900133 regulation of renin secretion into blood stream(GO:1900133)
0.0 0.0 GO:0019086 late viral transcription(GO:0019086)
0.0 0.1 GO:0072386 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.0 0.0 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.1 GO:1904707 positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.0 0.0 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.0 0.2 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.0 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.1 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.1 GO:0051790 short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.1 GO:1990144 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.0 0.1 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.0 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.1 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:1990001 inhibition of cysteine-type endopeptidase activity(GO:0097340) zymogen inhibition(GO:0097341) inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0048643 positive regulation of skeletal muscle tissue development(GO:0048643)
0.0 0.1 GO:0098908 regulation of neuronal action potential(GO:0098908)
0.0 0.0 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.0 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.0 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.0 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.0 0.0 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.1 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.5 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.0 GO:1901660 calcium ion export(GO:1901660)
0.0 0.0 GO:0033091 positive regulation of immature T cell proliferation(GO:0033091) positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.0 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.0 GO:0021648 vestibulocochlear nerve morphogenesis(GO:0021648)
0.0 0.0 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.2 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:1902414 protein localization to cell junction(GO:1902414)
0.0 0.0 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.0 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.0 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.0 0.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.0 0.0 GO:0046292 formaldehyde metabolic process(GO:0046292)
0.0 0.0 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.0 0.0 GO:1903223 positive regulation of oxidative stress-induced neuron death(GO:1903223)
0.0 0.1 GO:0071265 amino acid salvage(GO:0043102) L-methionine biosynthetic process(GO:0071265) L-methionine salvage(GO:0071267)
0.0 0.1 GO:0044381 glucose import in response to insulin stimulus(GO:0044381) regulation of glucose import in response to insulin stimulus(GO:2001273)
0.0 0.0 GO:0048617 embryonic foregut morphogenesis(GO:0048617)
0.0 0.0 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0002082 regulation of oxidative phosphorylation(GO:0002082)
0.0 0.1 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.0 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.0 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.0 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.1 GO:0035089 establishment of apical/basal cell polarity(GO:0035089)
0.0 0.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.3 GO:0042567 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.3 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.2 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.1 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.1 GO:0070775 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.0 0.2 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0032039 integrator complex(GO:0032039)
0.0 0.1 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.1 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0097149 centralspindlin complex(GO:0097149)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.1 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.0 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.0 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0035363 histone locus body(GO:0035363)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.1 GO:0070852 cell body fiber(GO:0070852)
0.0 0.0 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958)
0.0 0.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.1 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.0 GO:0097513 myosin II filament(GO:0097513)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 1.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.4 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.1 0.3 GO:0032564 dATP binding(GO:0032564)
0.1 0.1 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.1 0.2 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.8 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.1 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.2 GO:0004083 bisphosphoglycerate 2-phosphatase activity(GO:0004083)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.1 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.2 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0005329 dopamine transmembrane transporter activity(GO:0005329)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.0 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 0.1 GO:0004075 biotin carboxylase activity(GO:0004075)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.1 GO:0019808 polyamine binding(GO:0019808)
0.0 0.1 GO:0004370 glycerol kinase activity(GO:0004370)
0.0 0.1 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.0 0.1 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001)
0.0 0.1 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.0 0.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.1 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0004833 tryptophan 2,3-dioxygenase activity(GO:0004833)
0.0 0.1 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.0 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.0 0.1 GO:0008898 S-adenosylmethionine-homocysteine S-methyltransferase activity(GO:0008898)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.1 GO:0016679 oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.1 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:2001070 starch binding(GO:2001070)
0.0 0.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.0 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.0 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.0 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0047105 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.1 GO:0016744 transferase activity, transferring aldehyde or ketonic groups(GO:0016744)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.1 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.0 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.2 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0035325 Toll-like receptor binding(GO:0035325)
0.0 0.0 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.6 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.0 GO:0019961 interferon binding(GO:0019961)
0.0 0.2 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.0 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.1 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0005381 iron ion transmembrane transporter activity(GO:0005381)
0.0 0.0 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.0 GO:0070573 metallodipeptidase activity(GO:0070573)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.0 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0052771 coenzyme F390-A hydrolase activity(GO:0052770) coenzyme F390-G hydrolase activity(GO:0052771)
0.0 0.0 GO:0016421 CoA carboxylase activity(GO:0016421)
0.0 0.0 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.0 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.0 GO:0004920 interleukin-10 receptor activity(GO:0004920)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.1 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.6 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.0 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.0 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.3 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.2 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.5 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.4 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.2 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.6 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.2 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR